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Relevant bibliographies by topics / Oncogenes / Dissertations / Theses

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Dissertations / Theses on the topic 'Oncogenes'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

SCHAFFHAUSER, CHRISTOPHE. "Les oncogenes viraux." Strasbourg 1, 1987. http://www.theses.fr/1987STR10692.

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2

Pandey, Vijay. "Secreted oncogenes in endometrial carcinoma." Thesis, University of Auckland, 2010. http://hdl.handle.net/2292/8195.

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Endometrial carcinoma is the most common malignancy of the female reproductive tract and the incidence in developed countries is rising. Poor survival of late stage and recurrent endometrial carcinoma patients, particularly with an aggressive histologic subtype, necessitate the development of new therapeutic modalities for advanced stage and recurrent endometrial carcinoma. Recent published data have demonstrated elevated levels of human growth hormone (hGH) in endometriosis and endometrial adenocarcinoma. Herein, I demonstrate that autocrine production of hGH can enhance the in vitro a

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3

Scully, Jaqueline Susan. "Insertion of oncogenes into mouse mammary epithelium." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315287.

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4

Williams, Alistair Robert William. "Expression of oncogenes in human colorectal neoplasms." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/19415.

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5

Imler, Jean-Luc. "Identification d'une cible transcriptionnelle pour les oncogenes." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13193.

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6

Gerlinger, Emmanuel. "Proto-oncogenes et developpement embryonnaire : etude bibliographique." Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR1M202.

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7

Jaggi, Rolf. "Interaction of oncogenes with the glucocorticoid receptor /." Bern, 1989. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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8

Kemble, David J. "A biochemical study on the regulation of the SRC and FGFR family of protein tyrosine kinases /." View online ; access limited to URI, 2009. http://0-digitalcommons.uri.edu.helin.uri.edu/dissertations/AAI3367994.

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9

Jenkins, Brendan John. "Activating point mutations in the common ?gb?s[beta]-subunit of the human GM-CSF, IL-3 and IL-5 receptors : implications for receptor function and role in disease / by Brendan John Jenkins." Title page, contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phj518.pdf.

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10

Bartel, Courtney A. "Novel Roles for FAM83 Oncogenes in Breast Cancer." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1512682785418426.

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11

Collins-De, Peyer Laurence. "Screening of a rat thymus and a human hippocampus cDNA library for a novel fyn-related oncogene." Thesis, Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21253870.

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12

Chen, Leilei. "Identification and characterization of CHD1L in hepatocellular carcinoma." Click to view the E-thesis via HKUTO, 2010. http://sunzi.lib.hku.hk/hkuto/record/B44139810.

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13

McCarthy, E. C. "Analysis of the subcellular and tissue-specific expression of the tumoursuppressor protein PTEN in Drosophila : regulation and function." Thesis, University of Kent, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270708.

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14

Foster, Keith. "Molecular genetic analysis of non-familial renal cell carcinoma." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289811.

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15

Morland, Sarah J. "A molecular genetic analysis of endometriosis and the association with ovarian cancer." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323802.

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16

McKibbon, Valerie Lynn. "Dopaminergic and glutamatergic mechanisms influence immediate-early gene expression in rodent brain." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283934.

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17

Xu, Zhi. "Yes associated protein (YAP) in hepatocellular carcinoma oncogenic functions and molecular targeting /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43278589.

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18

Scheijen, Gemma Petronella Helena. "Characterization of the Myc collaborating oncogenes Bmi1 and Gfi1." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/84673.

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19

Sinha, S. "The role of oncogenes in experimental rat liver cancer." Thesis, Open University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234898.

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20

Abram, Clare L. "Expression of oncogenes in mouse mammary epithelium by transplantation." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307957.

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21

Riedinger, Christiane. "Tumour suppressors and oncogenes : Structure, function and drug design." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.533846.

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22

Lucas, John Mark. "Regulation of the C-MYC and FGF-4 Oncogenes /." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487859879939229.

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23

Zhang, Juan. "ONCOGENES INVOLVED IN CANCER CELL PROGRESSION AND CELL SURVIVAL." OpenSIUC, 2012. https://opensiuc.lib.siu.edu/theses/830.

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Serum is an essential component of cell cultural medium. Besides nutrients, it supplies various growth factors which are indispensable for growth, proliferation, and survival. Prolonged serum starvation treatment usually will induce cell to enter a quiescent state (G0) or go to apoptosis. In the present study, we hypothesized that some microRNAs (miRNAs) may promote cancer cell survival under prolonged serum starvation treatment. We used cell culture medium without any serum to culture HCT-116 wild type cells infected with the miRNA library consisting of over 600 miRNA precursors in a lentivi

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24

Murcia, Rosero Lada. "Selective killing of Ras-malignant tisues by exploiting oncogene-induced DNA damage = Eliminación selectiva de tejidos malignos dependientes de RAS mediante la explotación del daño en el ADN inducido por oncogenes." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668212.

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Most human solid tumors present signs of genomic instability. Activated oncogenes have been proposed to induce genomic instability through the generation of replicative stress. In this thesis, we have sown that the expression of a constitutively active form of RAS oncogene promotes accelerated G1/S transition which leads to replicative stress and genomic instability. The resulting DNA damage present in these cells should activate the DDR response, however, RasV12 cells impair DNA damage signaling. Furthermore, RasV12 expression inhibits apoptosis through ERK. RAS is one of the most commonly m

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25

Bennett, Julie Denise. "Cell cycle regulation of B-myb transcription." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362337.

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26

溫錫剛 and Shek-kong Thomas Wan. "Establishment and characterization of human ovarian surface epithelialcells immortalized by human papilloma viral oncogenes." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31236236.

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27

Littlewood, Trevor David. "An investigation of the functions of the c-Myc oncoprotein." Thesis, Anglia Ruskin University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357338.

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28

Feng, Liang. "Molecular analysis of the ewings sarcoma oncogene transcriptional activation domain /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202002%20FENG.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2002.<br>Includes bibliographical references (leaves 74-85). Also available in electronic version. Access restricted to campus users.

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29

Wan, Shek-kong Thomas. "Establishment and characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes /." Hong Kong : University of Hong Kong, 1997. http://sunzi.lib.hku.hk/hkuto/record.jsp?B18656456.

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30

Dutenhefner, Simone Elisa. "Pesquisa da mutação T1799A do gene BRAF e a presença de metástases linfáticas no carcinoma papilífero da tireoide." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-24012012-163817/.

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Muitos pacientes submetidos à tireoidectomia por Carcinoma Papilífero da Tireoide (CPT) têm doença linfonodal subclínica no momento da cirurgia. A mutação BRAF T17799A (V600E) é um evento comum no CPT e alguns estudos demonstram correlação entre a mutação e características de maior agressividade tumoral, incluindo a presença de metástases linfonodais. O esvaziamento eletivo do compartimento central ganha aceitação, uma vez que alguns estudos evidenciam que a presença de metástases linfonodais aumenta o risco de recidiva e mortalidade. Devido ao grande potencial de complicações do esvaziamento

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31

Velasco, Sánchez Ana. "Oncogenes y genes supresores de tumores en carcinoma de endometrio." Doctoral thesis, Universitat de Lleida, 2012. http://hdl.handle.net/10803/110545.

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El objetivo principal de este trabajo ha sido la identificación de alteraciones moleculares que participen de manera significativa en el desarrollo y la progresión del cáncer de endometrio, con el propósito de añadir mas claves para el descubrimiento de nuevas dianas de diagnosis y terapias individuales contra esta patología. El trabajo ha sido centrado en el estudio de modificaciones en el ADN de las células que forman el tejido tumoral en una serie de pacientes con carcinoma endometrial, en concreto, en el análisis mutacional de los genes PIK3CA y FGFR2 y el análisis de hipermetilación del p

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32

Ewels, Philip Andrew. "Spatial organisation of proto-oncogenes in human haematopoietic progenitor cells." Thesis, University of Cambridge, 2013. https://www.repository.cam.ac.uk/handle/1810/245861.

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The eukaryotic cell nucleus is a highly organised organelle, with distinct specialised sub- compartments responsible for specific nuclear functions. Within the context of this functional framework, the genome is organised, allowing contact between specific genomic regions and sub-compartments. Previous work has shown that genes in both cis and trans can make specific contacts with each other. I hypothesise that such a preferred juxtaposition may impact the propensity for specific cancerinitiating chromosomal translocations to occur. In this thesis, I describe how I have extended and developed

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33

Kiberu, Samuel. "Apoptosis, cell proliferation and role of oncogenes in lymphoreticular malignancies." Thesis, University of Leicester, 1998. http://hdl.handle.net/2381/29571.

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This study was conducted using paraffin embedded material of randomly selected lymphoma cases from the archives of Leicester Royal Infirmary. The cases had been confirmed by immunophenotyping and immunocytogenetic analysis of B and T cell gene rearrangements using PCR (Polymerase chain reaction). These included 20 each of low grade and high grade non Hodgkin's lymphomas of both sexes and age groups 4-84 yrs. Prognostic information was obtained from the case notes. An in situ End labelling technique was used to study apoptotic indices. Cell proliferation rates were studied by in situ hybridisat

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34

Gottardo, Nicholas G. "Oncogenes and prognosis in childhood T-cell acute lymphoblastic leukaemia." University of Western Australia. School of Paediatrics and Child Health, 2008. http://theses.library.uwa.edu.au/adt-WU2009.0039.

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[Truncated abstract] The treatment of childhood acute lymphoblastic leukaemia (ALL) is one of the great success stories of paediatric oncology, transforming a universally fatal disease into one where 75 to 90% of children are now cured. Although in the past survival for children with T-cell ALL (T-ALL) lagged behind that of children with pre-B ALL, the use of contemporary intensified treatment strategies has significantly diminished this difference, with many investigators reporting similar cure rates for both groups of patients. Despite these marked improvements, numerous challenges still fac

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35

Persson, Fredrik. "Studies of fusion oncogenes and genomic imbalances in human tumors /." Göteborg : Göteborg University, Lundberg Laboratory for Cancer Research, Dept. of Pathology, Sahlgrenska Academy at Göteborg University, 2007. http://hdl.handle.net/2077/7368.

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36

Maxwell, Marius. "Expression of proto-oncogenes and growth factors in glioblastoma multiforme." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259967.

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37

Mellon, Killian. "C-ERBB oncogenes and cell cycling in human bladder cancer." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333949.

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38

Arends, Mark J. "Regulation of tumour growth and apoptosis by oncogenes and papillomaviruses." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/19771.

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The role of HPV genomes in human cervical neoplasia was re-examined using a new, sensitive PCR-based assay. This demonstrated increasing HPV prevalence with increasing grade of histological abnormality in cervical neoplasia. In contrast, HPV was not observed in histologically normal epithelium from a control group of women defined without reference to attendance at gynaecological or sexually transmitted disease clinics. HPV 16 was associated more with squamous cell carcinomas, and HPV 18 with cancers showing glandular differentiation - the histological type with a poorer prognosis. HPV 18 had

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39

Wallingford, John Beckett. "Tumor suppressors and oncogenes in the development of Xenopus laevis /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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40

PANDINI, CECILIA. "MYC and MINCR characterization in ALS: oncogenes role in neurodegeneration." Doctoral thesis, Università degli studi di Pavia, 2020. http://hdl.handle.net/11571/1370056.

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41

Santiago, Marília Bueno 1986. "Avaliação dos polimorfismos SLC23A2-05 e KRAS-LCS6 entre portadores de carcinoma de células escamosas de cabeça e pescoço." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308579.

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Orientador: Carmen Silvia Bertuzzo<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-18T22:32:33Z (GMT). No. of bitstreams: 1 Santiago_MariliaBueno_M.pdf: 1534598 bytes, checksum: 1b88c82597c2b286ee6cd5c4c13cec4b (MD5) Previous issue date: 2011<br>Resumo: O câncer é um dos problemas mais comuns da medicina atual, com cerca de 481.100 novos casos por ano, atingindo mais de um terço da população mundial. O câncer de cabeça e pescoço em sua maioria é representado por neoplasias epiteliais do tipo carcinoma de célu

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42

Bellmunt, i. Tarragó Anna. "Role of MAF in bone metastasis." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/482079.

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The identification of genes that mediate metastasis is pivotal to better understand the mechanism, to develop novel drugs and to stratify patients with highest risk and consecutively administrate them preventive treatments. Despite significant advances on knowledge, diagnosis and treatment of cancer, metastasis remains the major cause of cancer-associated deaths. Bone is one of the most common organs affected by metastatic lesions for its permeability and favorable conditions for cellular growth. Constant remodeling in bone homeostasis implies an incessant degradation of the bone that relea

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43

Dix, Flora Lucy. "Ceramide synthase 4 : a novel metabolic regulator of oncogene-induced senescence." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29624.

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Senescence is a cell stress program characterized by a stable cell cycle arrest and thus aims to protect against replication of potentially harmful cells. In oncogene-induced senescence (OIS) the cell cycle arrest is brought about by activation of an oncogene. This in turn initiates a DNA damage response and subsequently, the DDR induces p53-p21 and RB tumour suppressor pathways. The metabolism of senescent cells is highly altered, notably there is increased secretion of proteins and increased functional activity of certain metabolic enzymes. There have been many recent studies investigating t

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44

Barbieri, Raquel Bueno 1985. "Perfil genético de suscetibilidade ao desenvolvimento de carcinoma medular de tireoide." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310291.

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Orientadores: Laura Sterian Ward, Janete Cerutti<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-20T07:05:33Z (GMT). No. of bitstreams: 1 Barbieri_RaquelBueno_M.pdf: 1118684 bytes, checksum: aea72fb3df76b68d6756c422b46ffc56 (MD5) Previous issue date: 2012<br>Resumo: Polimorfismos de genes baixa penetrância têm sido consistentemente associados com a suscetibilidade a uma série de tumores humanos, incluindo o câncer de tireóide. A fim de determinar seu papel no carcinoma medular de tireóide (CMT), foi utilizado

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45

Mahmoudi, Massoud. "Induction of Interferon Messenger RNA and Expression of Cellular Oncogenes in Human Lymphoblastoid Cells." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc798199/.

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The purposes of this study was to demonstrate the induction of alpha interferon mRNA in Sendai virus-induced Namalava cells, to follow the level of alpha interferon mRNA synthesis at the transcriptional level, and to determine whether the Namalava cell line expresses the c-myc oncogene and to what degree. The amount of c-myc message deteted in Namalva cell RNA was about one-tenth that of Daudi cell RNA, whereas no difference in the amount of the c-Ha-ras message was observed between the two cell lines.

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46

Sandros, Jens. "Salivary gland tumorigenesis a cytogenetic and molecular study /." Göteborg : Faculty of Odontology, University of Göteborg, University of Göteborg, 1989. http://catalog.hathitrust.org/api/volumes/oclc/20361247.html.

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47

Kwek, Chin Kiat Women's &amp Children's Health Faculty of Medicine UNSW. "Isolation and characterisation of inhibitors of leukaemia with translocatins involving the mixed lineage leukaemia oncogene." Awarded by:University of New South Wales, 2007. http://handle.unsw.edu.au/1959.4/38520.

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Acute lymphoblastic leukaemia is the most common childhood cancer with cure rates of approximately 80%. This success can be attributed to the introduction of risk stratification for patients and employment of intensified treatment regimes for patients with high risk disease. However, the identification of prognostically important leukaemia subtypes, unfortunately, is an labour-intensive process. In addition, despite the success in treating childhood ALL, specific subgroups of patients nevertheless still have poor survival rates. This is particularly true for leukaemias characterised by chromo

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48

Tang, Dongjiang. "Functional studies of SEI-1 and eIF5A2 : candidate oncogenes isolated from frequently amplified regions of ovarian carcinomas /." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36889775.

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49

Lee, Wing-sang, and 李榮生. "The prognostic significance of DJ-1 in patients with renal cell carcinoma of clear cell type." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42925095.

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50

Fallows, Sarah Aileen Sharon. "A study of p53 in epithelial ovarian cancer." Thesis, Queen's University Belfast, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263321.

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