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Journal articles on the topic 'Ond tro'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Riess, H., S. Drechsler, C. Evers, and L. Faerber. "Tropisetron (TRO) VS. ondansetron (OND) in prophylaxis of chemotherapy-induced emesis (CIE)." European Journal of Cancer 29 (January 1993): S211. http://dx.doi.org/10.1016/0959-8049(93)91800-z.

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2

Swartz, Richard, and Klaus Carsten Pedersen. "Serbernes sammenstød med virkeligheden." Udenrigs, no. 1 (March 1, 2008): 24–37. http://dx.doi.org/10.7146/udenrigs.v0i1.119459.

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Mange serbere er tilbøjelige til at tro, at deres vanskeligheder skyldes en ond omverden og ikke deres egne valg. De mener, at de har retten til Kosovo, skønt de ikke aner, hvad de i givet fald skulle stille op med to millioner albanere

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3

Bradley, Natalie. "Too old to sedate: How old is too old?" Dental Update 48, no. 2 (February 2, 2021): 106–13. http://dx.doi.org/10.12968/denu.2021.48.2.106.

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The UK population is ageing with over a quarter of people predicted to be over 65 by 2040. People are retaining their teeth into old age, often having experienced complex restorative dental work over the years. The increasing complexity of dental treatment that older people require will create challenges for those who provide care for this population, including dental treatment under sedation or general anaesthesia. This article discusses the medical, dental and social considerations that need to be taken into account when planning dental care for older patients under sedation or general anaesthesia. CPD/Clinical Relevance: Dentists who provide sedation must be able to appropriately assess and manage their older patients safely if considering this method of pain and anxiety control for dental treatment.

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4

Cohen, Gene D. "How Old Is Too Old?" American Journal of Geriatric Psychiatry 1, no. 2 (March 1993): 91–93. http://dx.doi.org/10.1097/00019442-199300120-00001.

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5

MUÑOZ, RODRIGO A. "‘Too Soon Old, Too Late Smart’." Clinical Psychiatry News 33, no. 6 (June 2005): 78. http://dx.doi.org/10.1016/s0270-6644(05)70479-3.

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6

Ball, S. G. "Thrombolysis: too old and too young." Heart 87, no. 4 (April 1, 2002): 312–13. http://dx.doi.org/10.1136/heart.87.4.312.

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7

Rademacher, Tom. "Never Too Old." Journal of Christian Nursing 4, no. 1 (1987): 15–17. http://dx.doi.org/10.1097/00005217-198704010-00005.

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8

de Souza, Ricardo Krause Martinez, Rodrigo Tomazini Martins, Samanta Fabrício Blattes da Rocha, Henry Koiti Sato, and Pedro André Kowacs. "Never too old." Lancet 378, no. 9803 (November 2011): 1676. http://dx.doi.org/10.1016/s0140-6736(11)61225-7.

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9

Walker, Anne. "Not Too Old." Physiotherapy 79, no. 4 (April 1993): 263. http://dx.doi.org/10.1016/s0031-9406(10)60716-x.

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10

Faulde, Debi. "Not Too Old." Physiotherapy 79, no. 4 (April 1993): 263. http://dx.doi.org/10.1016/s0031-9406(10)60717-1.

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11

Leslie, M. "Never Too Old?" Science of Aging Knowledge Environment 2004, no. 13 (March 31, 2004): nf35. http://dx.doi.org/10.1126/sageke.2004.13.nf35.

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12

Castledine, George. "How old is too old (or too young) to resuscitate?" British Journal of Nursing 15, no. 5 (March 2006): 245. http://dx.doi.org/10.12968/bjon.2006.15.5.20647.

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13

Rhee, Chin Kook. "Old Friends, Old Wine, and Old COPD Classification Are Best." Tuberculosis and Respiratory Diseases 81, no. 4 (2018): 347. http://dx.doi.org/10.4046/trd.2018.0071.

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14

Patel, J., M. A. Kawano, K. K. Kiyosaki, A. Ankrom, M. Kittleson, J. Moriguchi, A. Ardehali, and J. Kobashigawa. "390: When Is Too Old, Too Old for Redo Heart Transplantation?" Journal of Heart and Lung Transplantation 28, no. 2 (February 2009): S200—S201. http://dx.doi.org/10.1016/j.healun.2008.11.397.

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15

DeRoo, Scott, and Hiroo Takayama. "Commentary: How Old Is Too old?" Seminars in Thoracic and Cardiovascular Surgery 32, no. 4 (2020): 653–54. http://dx.doi.org/10.1053/j.semtcvs.2020.03.009.

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16

Campbell, Andrew, Osamu Tanabe, Rebekah Urbonya, Andrea Mathias, Lihong Shi, Kwaku Osei Bonsu, Rhonda Douglas, et al. "Analysis of Fetal Hemoglobin Expression within Humanized Sickle Cell Disease Mice Overexpressing the TR2/4 Transgene." Blood 116, no. 21 (November 19, 2010): 1619. http://dx.doi.org/10.1182/blood.v116.21.1619.1619.

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Abstract Abstract 1619 Background: Sickle Cell Disease (SCD) is a chronic debilitating hematologic condition caused by a missense mutation within the adult beta globin gene leading to significant morbidity and mortality. Increased Fetal Hemoglobin production has been shown to significantly ameliorate SCD symptoms and improve survival. A novel specific DNA-binding factor DRED (direct repeat erythroid definitive) was recently identified that regulated epsilon and gamma globin gene expression (Tanimoto et al Genes Dev 2000). Purification of DRED revealed that it harbored the nuclear orphan hormone receptors, TR2/TR4, as its DNA binding core (Tanabe et al EMBO 2002). Overexpression of TR2/TR4 Transgene within Human Beta Globin Yeast Artificial Chromosome Transgenic Mice resulted in 4-fold induction of the gamma globin mRNA levels (Tanabe et al EMBO 2007). Therefore, we wanted to determine if the overexpression of TR2/TR4 within a humanized sickle cell disease model would result in fetal hemoglobin induction. Methods: Humanized Homozygous Knock-In UAB-Sickle Cell (UAB-Hbahα/hα Hbbhβs/hβs) Mice (Wu et al Blood 2006) was mated to TR2/TR4 Overexpressing Mice (TgTR2/TR4) to generate homozygous SS-TR2/TR4 compound heterozygotes (UAB-Hba hα/hα Hbb hβs/hβs TgTR2/TR4). We generated four 2–3 month old homozygous SS-TR2/TR4 transgenic mice and compared hemoglobin F levels, complete blood cell counts and % body weight (liver, spleen, kidney) to six 2–3 month old homozygous SS mice (Hbahα/hα Hbb hβs/hβs)without the overexpressing TgTR2/TR4. Tail PCR genotyping of all sickle cell mice (with and without TgTR2/TR4) and Hemoglobin F(Hgb F) and Sickle (HgbS) levels were confirmed by HPLC Hemoglobin electrophoresis. Results: The mean Hgb F: 7.8% (n=6, sd 1.63+/−) in the homozygous SS control mice vs. 16.5% (n=4, sd 2.64+/−)in the homozygous SS-TR2/4 Mice (2 Fold higher). Hematologic profile revealed a mean Hct: 25.2 (n=6, sd 5.50 +/−) mean MCV: 75.4 (n=6, sd 10+/−) and a mean WBC: 22.6 (n= 6, sd 13.9 +/−) in the homozygous SS control mice vs. a mean Hct: 31.25(n=4, sd 6.89+/−), mean MCV: 61(n=4, sd 3.5+/−) mean WBC: 16.3(n= 4, sd 5.99+/−) in the homozygous SS-TR2/TR4 mice. Lastly, initial organ (spleen, liver, kidney) pathology evaluation revealed decreased % body weight (bw) in homozygous SS TR2/TR4 Mice vs. homozygous SS controls: 1) Spleen %bw: 4.3% vs. 3.5% TgTR2/TR4), 2) Liver % bw: 8.8% vs. 7.7% TgTR2/TR4), and 3) Kidney %bw: 1.14% vs. 1.02% TgTR2/TR4). Conclusions: Our preliminary analysis revealed that TR2/TR4 overexpression within a humanized sickle cell disease mouse model resulted in a 2-fold induction of fetal hemoglobin based on HPLC hemoglobin electrophoresis. Further, increased TR2/TR4 overexpression improved anemia and organomegaly within sickle cell disease mice. TR2/TR4 may be an attractive target for fetal hemoglobin induction for the treatment of sickle cell disease. Ongoing studies will determine if TR2/TR4 decreases organ specific disease pathology. We will also determine the cellular distribution of fetal hemoglobin in future studies. Disclosures: No relevant conflicts of interest to declare.

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17

FRANK, PATRICK. "Too old at 30." Nature 325, no. 6102 (January 1987): 294. http://dx.doi.org/10.1038/325294d0.

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18

Van Epps, Heather L. "Too old to help." Journal of Experimental Medicine 201, no. 6 (March 21, 2005): 831. http://dx.doi.org/10.1084/jem2016iti3.

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19

Patterson, J. "You're never too old." BMJ 308, no. 6934 (April 9, 1994): 986. http://dx.doi.org/10.1136/bmj.308.6934.986.

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20

Penson, Richard T., Kristy J. Daniels, and Thomas J. Lynch. "Too Old to Care?" Oncologist 9, no. 3 (June 2004): 343–52. http://dx.doi.org/10.1634/theoncologist.9-3-343.

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21

King, Patricia. "Too old to treat?" BMJ 336, Suppl S1 (January 1, 2008): 0801007. http://dx.doi.org/10.1136/sbmj.0801007.

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22

Gosby, Janice. "Too old to learn?" Nursing Management 9, no. 1 (January 1, 1989): 18. http://dx.doi.org/10.7748/nm.9.1.18.s12.

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23

Thibault, George E. "Too Old for What?" New England Journal of Medicine 328, no. 13 (April 1993): 946–50. http://dx.doi.org/10.1056/nejm199304013281309.

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24

Wong, John B., Deeb N. Salem, and Stephen G. Pauker. "You're Never Too Old." New England Journal of Medicine 328, no. 13 (April 1993): 971–75. http://dx.doi.org/10.1056/nejm199304013281319.

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25

Merrell, Ronald C., and Charles R. Doarn. "Too Old for Telemedicine?" Telemedicine and e-Health 19, no. 6 (June 2013): 431–32. http://dx.doi.org/10.1089/tmj.2013.9992.

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26

Anthony, Maureen. "Youʼre Never Too Old." Home Healthcare Now 36, no. 3 (2018): 145–46. http://dx.doi.org/10.1097/nhh.0000000000000688.

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27

Vroomen, P. C. A. J. "Too old to thrombolyse?" Journal of Neurology, Neurosurgery & Psychiatry 77, no. 7 (March 20, 2006): 812. http://dx.doi.org/10.1136/jnnp.2006.091520.

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28

Strik, Marc, Kevin Vernooy, and Frits W. Prinzen. "Too old to shock?" International Journal of Cardiology 263 (July 2018): 65–66. http://dx.doi.org/10.1016/j.ijcard.2018.04.036.

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29

Spilker, Hendrik Storstein. "Too Old to Rock'n'Roll?" Nordic Journal of Digital Literacy 5, no. 02 (December 6, 2010): 134–52. http://dx.doi.org/10.18261/issn1891-943x-2010-02-05.

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30

Blok, Joris J., Johan W. de Fijter, Andries E. Braat, Merel J. Verhagen, and Jan Ringers. "Old-to-old pancreas transplantation, what is old in the USA may be young in Europe." Transplant International 27, no. 4 (December 27, 2013): e31-e32. http://dx.doi.org/10.1111/tri.12236.

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31

Kayler, Liise K., Xuerong Wen, Mareena Zacharai, Michael Casey, Jesse Schold, and Joseph Magliocca. "Response: old-to-old pancreas transplantation, what's old in the USA may be young in Europe." Transplant International 27, no. 4 (January 17, 2014): e33-e33. http://dx.doi.org/10.1111/tri.12260.

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32

He, Xiaoning, Joanna M. Bridger, and Ian R. Kill. "Too old, too soon: Hutchinson–Gilford progeria syndrome." Biochemist 30, no. 5 (October 1, 2008): 18–22. http://dx.doi.org/10.1042/bio03005018.

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Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disease that is characterized by precocious aging in infants and always leads to early death from heart attacks or strokes at a mean age of around 13–14 years. The premature aging is manifest through cutaneous changes resembling normal aged skin, alopecia (hair loss), lipodystrophy, skeletal changes (coxa valga and low bone mineral density, although this may not be due to osteoporosis as in normal aging, but rather a failure to properly develop bone throughout infancy) and intense atherosclerosis. Other changes commonly associated with aging are absent, such as cataracts and diabetes mellitus, and there are no reported problems with cognition or CNS neurology1. Thus HGPS belongs to the small group of genetic disorders called the segmental progeroid syndromes (Figure 1).

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33

Pridmore, Saxby. "Book Review: Too Soon Old, Too Late Smart." Australasian Psychiatry 14, no. 4 (December 2006): 422. http://dx.doi.org/10.1080/j.1440-1665.2006.02319.x.

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34

Ichino, Andrea, Guido Schwerdt, Rudolf Winter-Ebmer, and Josef Zweimüller. "Too old to work, too young to retire?" Journal of the Economics of Ageing 9 (June 2017): 14–29. http://dx.doi.org/10.1016/j.jeoa.2016.07.001.

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35

Maor-Sagie, Esther, Henry H. Chill, Shmiuel Herzberg, David Shweiky, Asher Shushan, and Avi Benshushan. "How old is “too old” for hysterectomy?" Maturitas 81, no. 1 (May 2015): 186. http://dx.doi.org/10.1016/j.maturitas.2015.02.248.

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36

Lee, Janet S., and Daniel B. Kim-Shapiro. "Stored blood: how old is too old?" Journal of Clinical Investigation 127, no. 1 (December 12, 2016): 100–102. http://dx.doi.org/10.1172/jci91309.

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37

Silver, GeorgeA. "THE OLD, THE VERY OLD, AND THE TOO OLD." Lancet 330, no. 8573 (December 1987): 1453. http://dx.doi.org/10.1016/s0140-6736(87)91142-1.

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38

Te Rijdt, Robert-Jan, Alice Tod, and Jane Turner. "Acquisitions: Old Master Drawings." Rijksmuseum Bulletin 66, no. 4 (December 15, 2018): 386–405. http://dx.doi.org/10.52476/trb.9765.

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39

Süsal, Caner, Gizem Kumru, Bernd Döhler, Christian Morath, Marije Baas, Jens Lutz, Christian Unterrainer, et al. "Should kidney allografts from old donors be allocated only to old recipients?" Transplant International 33, no. 8 (May 22, 2020): 849–57. http://dx.doi.org/10.1111/tri.13628.

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40

Pachana, Nancy A. "Too Old for Freedom? Not Too Late to Try." Clinical Gerontologist 42, no. 3 (March 5, 2019): 216–20. http://dx.doi.org/10.1080/07317115.2019.1590490.

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41

Barata, P. C., S. Oliveira, L. Mascarenhas, F. Gomes, C. Ribeiro, M. P. Custódio, L. B. Costa, A. Araújo, and L. Batarda. "Breast Cancer in Women: Too Young or Too Old?" Annals of Oncology 24 (May 2013): iii48. http://dx.doi.org/10.1093/annonc/mdt089.2.

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42

Chawluk, Antoni. "Is Soviet Capital Too Old?" Economica 54, no. 215 (August 1987): 335. http://dx.doi.org/10.2307/2554448.

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43

Deb, Saswata, and Stephen E. Fremes. "Are you ever too old?" Journal of Thoracic and Cardiovascular Surgery 149, no. 2 (February 2015): 485–86. http://dx.doi.org/10.1016/j.jtcvs.2014.10.063.

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44

Shah, Vinay A., Sandeep Randhawa, Thomas Mizen, Andrew G. Lee, and Rod Foroozan. "You're Too Old for That." Survey of Ophthalmology 53, no. 4 (July 2008): 403–10. http://dx.doi.org/10.1016/j.survophthal.2008.04.003.

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45

Glenny, Laura. "Too old to stop smoking?" British Journal of Community Nursing 23, no. 10 (October 2, 2018): 477. http://dx.doi.org/10.12968/bjcn.2018.23.10.477.

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46

Wallis, Claudia. "Never Too Old for Chemo." Scientific American 311, no. 6 (November 18, 2014): 34–35. http://dx.doi.org/10.1038/scientificamerican1214-34.

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47

French, Sally. "How Old is Too Otd?" Physiotherapy 79, no. 3 (March 1993): 195. http://dx.doi.org/10.1016/s0031-9406(10)60676-1.

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48

&NA;. "You???re Never Too Old." Journal of Occupational and Environmental Medicine 43, no. 4 (April 2001): 417. http://dx.doi.org/10.1097/00043764-200104000-00022.

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49

Hamilton, William. "Harold ? too old for treatment." Practical Diabetes International 19, no. 4 (2002): 123. http://dx.doi.org/10.1002/pdi.344.

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50

Garrison, Charlena. "You Are Never Too Old." Journal of Gerontological Nursing 34, no. 2 (February 1, 2008): 53–56. http://dx.doi.org/10.3928/00989134-20080201-07.

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