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Journal articles on the topic 'Onycholysis'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Kim, Ji-Yeon, Oh-Nam Ok, Jeong Ju Seo, Soo-Hyeon Lee, Jin Seok Ahn, and Yeon Hee Park. "A prospective randomized controlled trial of hydrating nail solution for prevention or treatment of onycholysis in breast cancer patients who received neoadjuvant/adjuvant docetaxel chemotherapy." Journal of Clinical Oncology 35, no. 15_suppl (2017): 10108. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.10108.

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10108 Background: Onycholysis and other nail toxicities occur in approximately 20-30% of breast cancer(BC) patients receiving docetaxel(D) chemotherapy. Onycholysis, the separation of the nail plate from nail bed, is also often associated with painful paronychia decreasing patients’ the efficacy of a hydrating nail solution (EVONAIL solution, Evaux Laboratories, France) for the prevention and treatment of D-induced onycholysis and nail toxicities. Methods: This study is a prospective randomized controlled study of hydrating nail solution for prevention or treatment of onycholysis in patients w

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2

Nakatsui, Thomas, and Andrew N. Lin. "Onycholysis and Thyroid Disease: Report of Three Cases." Journal of Cutaneous Medicine and Surgery 3, no. 1 (1998): 40–42. http://dx.doi.org/10.1177/120347549800300111.

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Background: Onycholysis is a common disorder with many causes. It is known to be associated with thyroid disease (especially hyperthyroidism), but physicians probably do not routinely screen for underlying thyroid disease. Objective: To study the association of onycholysis and thyroid disease. Methods: We report three patients with onycholysis who were investigated for thyroid disease. Results: In two patients, onycholysis was the presenting sign of previously undiagnosed hypothyroidism, whereas the third developed onycholysis while undergoing therapy for hypothyroidism. Conclusions: These thr

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3

Dominguez-Cherit, Judith, and Ralph C. Daniel. "Simple Onycholysis." Dermatologic Surgery 36, no. 11 (2010): 1791–93. http://dx.doi.org/10.1111/j.1524-4725.2010.01752.x.

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4

Neznakhina, M. S., G. A. Petrova, O. YE Garanina, I. L. Shlivko, D. O. Ellinsky, and K. S. Petrova. "Optimization of diagnostics and treatment of posttraumatic onycholysis." Vestnik dermatologii i venerologii 90, no. 1 (2014): 53–58. http://dx.doi.org/10.25208/0042-4609-2014-90-1-53-58.

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Onycholysis is a peculiar and prevalent nail affection conditioned by the detachment of the distal part of the nail from the nail bed. The absence of any reliable diagnostics criteria often results in diagnostics errors, inadequate treatment and reduced patient’s life quality. Goal of the research. To find out whether it is possible to use OCT for diagnosing onycholysis and Merz Spezial Dragees for the treatment of posttraumatic onycholysis, and to reasonably confirm the drug efficacy using OCT. Materials and methods. The study involved 15 volunteers with posttraumatic onycholysis aged 20-35 (

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5

Rault, Raymond. "Mycophenolate-Associated Onycholysis." Annals of Internal Medicine 133, no. 11 (2000): 921. http://dx.doi.org/10.7326/0003-4819-133-11-200012050-00023.

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6

BORDERS, JOHN V. "Captopril and Onycholysis." Annals of Internal Medicine 105, no. 2 (1986): 305. http://dx.doi.org/10.7326/0003-4819-105-2-305_2.

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7

Horio, Takeshi. "Spontaneous Photo-onycholysis." Journal of Dermatology 15, no. 6 (1988): 540–42. http://dx.doi.org/10.1111/j.1346-8138.1988.tb01206.x.

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8

Baran, Robert. "Onycholysis from hydroxylamine." Contact Dermatitis 24, no. 2 (1991): 158. http://dx.doi.org/10.1111/j.1600-0536.1991.tb01688.x.

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9

SPEECHLYDICK, M. "MITOZANTRONE-INDUCED ONYCHOLYSIS." Lancet 331, no. 8577 (1988): 113. http://dx.doi.org/10.1016/s0140-6736(88)90306-6.

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10

LOGAN, R. A., and J. L. M. HAWK. "Spontaneous photo-onycholysis." British Journal of Dermatology 113, no. 5 (1985): 605–10. http://dx.doi.org/10.1111/j.1365-2133.1985.tb02386.x.

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11

Mitchell, Paul L. R., and Vernon J. Harvey. "Mitozantrone-induced onycholysis." European Journal of Cancer 28, no. 1 (1992): 243–44. http://dx.doi.org/10.1016/0959-8049(92)90419-3.

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12

Makris, A., P. Mortimer, and T. J. Powles. "Chemotherapy-induced onycholysis." European Journal of Cancer 32, no. 2 (1996): 374–75. http://dx.doi.org/10.1016/0959-8049(95)00570-6.

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13

Baran, R. "Spontaneous photo-onycholysis." Journal of the European Academy of Dermatology and Venereology 5, no. 1 (1995): S20. http://dx.doi.org/10.1016/0926-9959(95)95819-m.

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14

Hanneken, S., U. Wessendorf, and N. J. Neumann. "Photodynamic onycholysis: first report of photo-onycholysis after photodynamic therapy." Clinical and Experimental Dermatology 33, no. 5 (2008): 659–60. http://dx.doi.org/10.1111/j.1365-2230.2008.02941.x.

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15

Issoual, K., A. Alaoui, K. Achehboune, et al. "Photo-Onycholysis : A Particular Chemotherapy-Induced Complication." Dermatology and Dermatitis 5, no. 1 (2020): 01–03. http://dx.doi.org/10.31579/2578-8949/062.

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Onycholysis or photo-onycholysis is a partial or total separation of the nail from the nail-bed secondary to chemotherapy, either alone or associated to ultraviolet phototherapy. It’is not a common side effect of anticancer therapy, even rarer with Paclitaxel. We report here one case.

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16

Jadhav, VikrantM, PradeepM Mahajan, and ChandrakantB Mhaske. "Nail pitting and onycholysis." Indian Journal of Dermatology, Venereology and Leprology 75, no. 6 (2009): 631. http://dx.doi.org/10.4103/0378-6323.57740.

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17

Al-Kathiri, Lutfi, and Abla Al-Asmaili. "Diclofenac-Induced Photo-Onycholysis." Oman Medical Journal 31, no. 1 (2016): 65–68. http://dx.doi.org/10.5001/omj.2016.12.

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18

Chang, Patricia, and Mónica Vanesa Vásquez Acajabón. "Onycholysis due to trauma." Our Dermatology Online 5, no. 2 (2014): 201–4. http://dx.doi.org/10.7241/ourd.20142.51.

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19

Baran, Robert, and Lennart Juhlin. "Drug-induced photo-onycholysis." Journal of the American Academy of Dermatology 17, no. 6 (1987): 1012–16. http://dx.doi.org/10.1016/s0190-9622(87)70291-6.

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20

Bentabet Dorbani, Imene, Talel Badri, Rym Benmously, Samy Fenniche, and Inçaf Mokhtar. "Griseofulvin-induced photo-onycholysis." La Presse Médicale 41, no. 9 (2012): 879–81. http://dx.doi.org/10.1016/j.lpm.2011.11.014.

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21

Im, Myung, Kyung-Chae Kye, Young-Joon Seo, Jeung-Hoon Lee, and Jang-Kyu Park. "Central trichoptilosis with onycholysis." International Journal of Dermatology 45, no. 10 (2006): 1187–88. http://dx.doi.org/10.1111/j.1365-4632.2006.02586.x.

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22

Schneider, Adina E., and Yaron Tomer. "Onycholysis Associated with Hypothyroidism." Thyroid 11, no. 7 (2001): 707. http://dx.doi.org/10.1089/105072501750362790.

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23

Rabar, Didier, Patrick Combemale, and François Peyron. "Doxycycline-Induced Photo-onycholysis." Journal of Travel Medicine 11, no. 6 (2006): 386–87. http://dx.doi.org/10.2310/7060.2004.19210.

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24

Zaias, N., S. X. Escovar, and M. N. Zaiac. "Finger and toenail onycholysis." Journal of the European Academy of Dermatology and Venereology 29, no. 5 (2014): 848–53. http://dx.doi.org/10.1111/jdv.12862.

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25

Fešar, Jaroslav. "Onycholysis in podology practice." Dermatologie pro praxi 17, no. 3 (2023): 138–41. http://dx.doi.org/10.36290/der.2023.026.

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26

Merad, Yassine, Hichem Derrar, Sarah Tabouri, and Faiza Berexi-Reguig. "<b><i>Candida guilliermondii</i></b> Onychomycosis Involving Fingernails in a Breast Cancer Patient under Docetaxel Chemotherapy." Case Reports in Oncology 14, no. 3 (2021): 1530–35. http://dx.doi.org/10.1159/000519695.

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Onychomycosis has been shown to have a higher incidence in cancer patients. Nail toxicity is a quite common side effect of anticancer agents. Taxotere<sup>©</sup> is a chemotherapeutic known to cause great incidence of nail change and has a role in subungual suppuration. We report on a 52-year-old woman with breast cancer admitted in our institution for onycholysis. Because of the stage and histology of breast cancer, neoadjuvant chemotherapy was initiated. The patient received 8 cycles of Taxotere and Adriamycin (AT), and she underwent a modified radical mastectomy. Three months l

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27

Chiheb, Soumiya, Zineb Tazi Saoud, Yasmine Mahdar, and Fouzia Hali. "DERMOSCOPIC FEATURES OF NAIL PSORIASIS AND CORRELATION WITH DISEASE SEVERITY." International Journal of Advanced Research 10, no. 05 (2022): 807–13. http://dx.doi.org/10.21474/ijar01/14775.

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Background / Objectives:Dermoscopy is a non-invasive technique that has been recognized recently as an effective tool in the diagnosis of nail diseases, including nail psoriasis. The aim of this study was to clarify specific dermoscopic features of nail psoriasis and identify those that are correlated with disease severity. Methods: We conducted a prospective study over 18 months. Fifty patients followed for psoriasis and nail involvement were enrolled. Following a clinical examination, the patients were classified according to the Nail Psoriasis Severity Index (NAPSI) and the Psoriasis Area a

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28

TSUTSUMI, Midori, Takamichi ITO, Yumi YASUKOCHI, Hiroshi UCHI, and Masutaka FURUE. "Terry's Nail Complicated with Onycholysis." Nishi Nihon Hifuka 79, no. 2 (2017): 119–20. http://dx.doi.org/10.2336/nishinihonhifu.79.119.

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29

Busso MD Msc., Corina, and Rashid Benitez MD. "Onycholysis Associated with Enalapril Therapy." International Journal of Research Studies in Medical and Health Sciences 5, no. 4 (2020): 1–2. http://dx.doi.org/10.22259/ijrsmhs.0504001.

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30

Rao, SD, S. Wavare, and S. Patil. "ONYCHOLYSIS CAUSED BY CANDIDA KRUSEI." Indian Journal of Medical Microbiology 22, no. 4 (2004): 258–59. http://dx.doi.org/10.1016/s0255-0857(21)02775-4.

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31

Urbano, Baldari, Antonio Ascari Raccagni, and Giuseppe Montini. "Onycholysis caused by chryseomonas luteola." Journal of the European Academy of Dermatology and Venereology 4, no. 1 (2006): 112–13. http://dx.doi.org/10.1111/j.1468-3083.1995.tb00301.x.

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32

Mahajan, Vikram K., and Nand Lal Sharma. "Photo-onycholysis due to sparfloxacin." Australasian Journal of Dermatology 46, no. 2 (2005): 104–5. http://dx.doi.org/10.1111/j.1440-0960.2005.00153.x.

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33

Rutherford, Tim, and Rodney Sinclair. "Photo-onycholysis due to indapamide." Australasian Journal of Dermatology 48, no. 1 (2007): 35–36. http://dx.doi.org/10.1111/j.1440-0960.2007.00324.x.

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34

Tinio, Patricia, Susan Bershad, and Jacob Oren Levitt. "Medical Pearl: Docetaxel-induced onycholysis." Journal of the American Academy of Dermatology 52, no. 2 (2005): 350–51. http://dx.doi.org/10.1016/j.jaad.2004.07.057.

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35

Cunningham, D., N. L. Gilchrist, G. J. Forrest, and M. Soukop. "Onycholysis associated with cytotoxic drugs." BMJ 290, no. 6469 (1985): 675–76. http://dx.doi.org/10.1136/bmj.290.6469.675-a.

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36

Helsing, Per, Joar Austad, and Hans Jørgen Talberg. "Onycholysis induced by nail hardener." Contact Dermatitis 57, no. 4 (2007): 280–81. http://dx.doi.org/10.1111/j.1600-0536.2007.01121.x.

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37

Curran, C. F. "Onycholysis in doxorubicin-treated patients." Archives of Dermatology 126, no. 9 (1990): 1244. http://dx.doi.org/10.1001/archderm.126.9.1244.

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38

Curran, Charles F. "Onycholysis in Doxorubicin-Treated Patients." Archives of Dermatology 126, no. 9 (1990): 1244. http://dx.doi.org/10.1001/archderm.1990.01670330124031.

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39

URBANO, B. "Onycholysis caused by chryseomonas luteola." Journal of the European Academy of Dermatology and Venereology 4, no. 1 (1995): 112–13. http://dx.doi.org/10.1016/0926-9959(94)00092-e.

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40

Hogeling, Marcia, Jessica Howard, Nordau Kanigsberg, and Harvey Finkelstein. "Onycholysis Associated with Capecitabine in Patients with Breast Cancer." Journal of Cutaneous Medicine and Surgery 12, no. 2 (2008): 93–95. http://dx.doi.org/10.2310/7750.2008.07028.

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Background: Onycholysis, which is separation of the nail plate from the nail bed at its distal and lateral attachments, can cause pain and impair function and is a well-known side effect of traditional chemotherapeutic agents. Objectives: We present two cases of onycholysis associated with capecitabine in women with advanced breast cancer, who were initially referred for evaluation of onychomycosis and review the literature on capecitabine. Conclusion: Owing to the increased frequency of use of capecitabine for different cancers, physicians should be aware of this side effect.

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41

Scotté, Florian, Jean-Marc Tourani, Eugeniu Banu, et al. "Multicenter Study of a Frozen Glove to Prevent Docetaxel-Induced Onycholysis and Cutaneous Toxicity of the Hand." Journal of Clinical Oncology 23, no. 19 (2005): 4424–29. http://dx.doi.org/10.1200/jco.2005.15.651.

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PurposeOnycholysis and skin toxicity occur in approximately 30% of patients treated with docetaxel. We investigated the efficacy and safety of an Elasto-Gel (84400 APT Cedex, Akromed, France) frozen glove (FG) for the prevention of docetaxel-induced onycholysis and skin toxicity.Patients and MethodsPatients receiving docetaxel 75 mg/m2alone or in combination chemotherapy were eligible for this case-control study. Each patient wore an FG for a total of 90 minutes on the right hand. The left hand was not protected and acted as the control. Onycholysis and skin toxicity were assessed at each cycl

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42

DALBETH, NICOLA, KAREN PUI, MARIA LOBO, et al. "Nail Disease in Psoriatic Arthritis: Distal Phalangeal Bone Edema Detected by Magnetic Resonance Imaging Predicts Development of Onycholysis and Hyperkeratosis." Journal of Rheumatology 39, no. 4 (2012): 841–43. http://dx.doi.org/10.3899/jrheum.111118.

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Objective.To examine the association between magnetic resonance imaging (MRI) features of distal phalanx (DP) disease and the progression of nail pathology in psoriatic arthritis (PsA).Methods.Clinical nail assessment and hand MRI scans were done on 34 patients with PsA. Twenty patients had repeat nail assessments after 1 year.Results.Nails with onycholysis and hyperkeratosis at baseline were more likely to have corresponding DP bone erosion and proliferation on MRI. DP bone edema on baseline MRI was associated with development of onycholysis and hyperkeratosis in corresponding nails.Conclusio

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43

Muth, Agnieszka, Sara Królik, Honorata Kubisiak-Rzepczyk, Zygmunt Adamski, and Dorota Jenerowicz. "Onycholysis associated with green nail dyschromia." Dermatology Review 107, no. 6 (2020): 546–50. http://dx.doi.org/10.5114/dr.2020.103890.

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44

Narayanan, Arunachalam, and Sruthy Mathew. "Onycholysis semilunaris – A factitious nail disorder." Cosmoderma 1 (September 10, 2021): 42. http://dx.doi.org/10.25259/csdm_51_2021.

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45

BAZEX, J., R. BARAN, F. MONBRUN, N. GRIGORIEFF-LARRUE, and M. C. MARGUERY. "Hereditary distal onycholysis-a case report." Clinical and Experimental Dermatology 15, no. 2 (1990): 146–48. http://dx.doi.org/10.1111/j.1365-2230.1990.tb02054.x.

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46

Chen, G.-Y., Y.-H. Chen, M. M. L. Hsu, C.-J. Tsao, and W.-C. Chen. "Onychomadesis and onycholysis associated with capecitabine." British Journal of Dermatology 145, no. 3 (2008): 521–22. http://dx.doi.org/10.1111/j.1365-2133.2001.04391.x.

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47

Obermair, A., M. Binder, M. Barrada, D. Bancher-Todesca, E. Asseryanis, and E. Kubista. "Onycholysis in patients treated with docetaxel." Annals of Oncology 9, no. 2 (1998): 230–31. http://dx.doi.org/10.1023/a:1008218824342.

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48

Torras, Helena, José Manuel Mascaró, and José M. Mascaró. "Photo-onycholysis caused by clorazepate dipotassium." Journal of the American Academy of Dermatology 21, no. 6 (1989): 1304–5. http://dx.doi.org/10.1016/s0190-9622(89)80312-3.

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49

Daniel, C. Ralph, Matilde Iorizzo, Bianca Maria Piraccini, and Antonella Tosti. "Grading simple chronic paronychia and onycholysis." International Journal of Dermatology 45, no. 12 (2006): 1447–48. http://dx.doi.org/10.1111/j.1365-4632.2006.03128.x.

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50

Chen, G.-Y., Y.-H. Chen, M. M. L. Hsu, C.-J. Tsao, and W.-C. Chen. "Onychomadesis and onycholysis associated with capecitabine." British Journal of Dermatology 145, no. 3 (2001): 521–22. http://dx.doi.org/10.1046/j.1365-2133.2001.04391.x.

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