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Dissertations / Theses on the topic 'Oocyte'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kazem, Rahnuma. "Oocyte cryopreservation." Thesis, University of Aberdeen, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282706.

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A questionnaire based survey was done to assess the views of fertile individuals, infertile individuals, egg donors and recipients towards gamete donation. The survey showed that fertile individuals were significantly less inclined towards the use of donated eggs in research and treatment, compared to infertile individuals. Acceptability of gamete donation was found to be very high in all groups regardless of their fertility, but the majority of individuals, whether fertile or infertile, were opposed to the use of fetal and cadaveric sources of obtaining eggs. The effect of modifications of th

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2

Marsh, Adam. "Oocyte-follicle interactions." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12684/.

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The ovarian follicle is an individual functional unit that provides the optimal environment for the oocyte within to develop. This thesis outlines the research in the field of ovarian follicular dynamics that has already been established, and further develops these findings to explore in greater detail the relationship between the oocyte and its environment, both in an in vitro and in vivo setting, using a variety of species. The first major research area involved studying the role of oocyte-secreted factors, which was examined using a series of dose response experiments. These were performed

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3

Wang, Ling. "Mouse oocyte maturation: How similar is it to frog oocyte maturation?" Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/27075.

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In this study, I have attempted to address the similarities/differences between amphibian and mouse oocytes by focusing on two aspects of mouse oocyte maturation. In the first project, I investigated the ability of several antagonists of serotonin receptors to initiate follicle-enclosed mouse oocytes to undergo maturation. I demonstrated that ritanserin, but not any others, was capable of inducing oocyte maturation in the intact mouse follicles. Significantly, ritanserin is also capable of inducing frog oocyte maturation, as demonstrated by others in our lab. These results therefore suggested

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4

Pfender, Sybille Helen. "Studies of asymmetric oocyte division and new genes controlling oocyte maturation." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648232.

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5

Yang, Min. "Evaluation of Oocyte Developmental Competence and Potential Strategies to Improve Oocyte Quality." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/6914.

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Assisted reproductive technologies (ARTs) have now been extensively used to promote reproductive efficiency as a fertility treatment not only in human medicine but also animal reproduction. ARTs serve as an important tool to advance the fundamental knowledge of reproductive processes. The quality of female’s eggs defines its ability to undergo maturation, fertilization, and development. This quality is determined by various factors and is crucial for the success of ARTs. Any alternations happening during the egg growth and maturation process can result in the decreased quality, which could hav

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6

Abdelsalam, Selima Mohamed. "Impact of oocyte vitrification." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/impact-of-oocyte-vitrification(d112e86b-faac-4b95-abff-06934e923ebd).html.

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Safe and effective oocyte cryopreservation will have a considerable impact on clinical practice in assisted reproduction. Great improvements have been made in recent years to oocyte vitrification procedures, although further controlled trials are necessary to ensure safety, and it is necessary to know more about pregnancy and live birth outcomes. This study aims to validate various methods of oocyte vitrification as assessed by comparative target gene analysis, hence contributing to information available to clinicians advising women about fertility preservation options before cancer treatment.

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7

Davies, S. "Oocyte maturation in mice." Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377928.

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8

Cox, Lindsay. "Oocyte Quality: Molecular Constituents Altered in the Oocyte Due to Various Environmental Factors." DigitalCommons@USU, 2016. https://digitalcommons.usu.edu/etd/5042.

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An estimated 1.6 million American couples struggle with infertility. Some causes for poor fertility can be clearly defined but in many instances, subfertility is unexplained. Poor oocyte quality is now considered to be a main contributing factor for many causes of infertility. Good oocyte quality is crucial for many processes including embryo development and maintaining pregnancy. There is a possibility that any alterations to the oocyte can have long lasting effects on embryo development and the health of the offspring. The oocyte is very sensitive to any perturbations to its surrounding envi

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9

Weingarten, Lisa Suzanne. "The oocyte-to-embryo transition : regulation of oocyte maturation and egg activation in Drosophila." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/79191.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Biology, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 33-39).<br>In oogenesis, meiosis must be highly regulated to ensure that growth of the oocyte and chromosomal segregation are coordinated properly. To do this, meiosis arrests at two points to permit oocyte differentiation and coordination with fertilization. In Drosophila, the first arrest in prophase I is released by oocyte maturation, and the second arrest in metaphase I is released by egg activation. This thesis explores mechanism

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10

Duffié, Rachel. "Epigenetic inheritance from the oocyte." Paris 6, 2013. http://www.theses.fr/2013PA066077.

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La méthylation de l’ADN est essentielle pour le développement des mammifères. Cette marque épigénétique peut être héritée des gamètes parentaux et influencer les phénotypes dans la descendance, un phénomène reconnu sous le nom d’empreinte parentale lorsque la transmission se fait de manière asymétrique depuis l’ovocyte et le spermatozoïde. Mon travail de thèse a concerné la méthylation spécifiquement héritée de l’ovocyte chez le modèle murin. J’ai tout d’abord montré que la méthylation ovocytaire est globalement dépendante du cofacteur d’ADN méthyltransférase DNMT3L. De manière importante, j’a

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11

Zhu, Jie. "Pig oocyte activation and developmental competence of parthenogenetically activated oocytes : in vitro and in vivo studies." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/27741.

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In somatic cell nuclear transfer in mammals, to clone a piglet is still a big challenge. Although many factors could contribute to the low success rate, such as quality of donor and recipient cells, types of donor cell including sources of animal breeds and tissues, number of passages and culture conditions, timing of cell cycle, procedures of nuclear transfer, techniques and embryos transfer, one of the factors is believed to be poor oocyte activation, especially in pig nuclear transfer. Therefore studies presented in this thesis aimed at the establishment of an in vitro culture system for pi

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12

Fineschi, Benedetta. "Selection of competent oocytes by morphological features. Can an artificial intelligence - based model predict oocyte quality?" Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1211555.

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Infertility is a significant problem of humanity. Despite the many advances in the field of assisted reproductive techniques (ART), accurately predicting the outcome of an in vitro fertilization cycle (IVF) has yet to be achieved. The focus of a great deal of research Is to improve on the current 30% success rate of IVF. Assessment of oocyte quality is probably the most important and difficult task in the ART. Oocyte quality has a direct impact on the fertilization and oocyte competence; the identification of oocyte quality markers is particularly important to select embryos with higher

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13

Hurtubise, Patricia. "Intracellular signalling during murine oocyte growth." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31239.

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During the growth phase of oogenesis, mammalian oocytes increase several hundred-fold in volume. Although it is known that ovarian granulosa cells send growth promoting signals, neither these external signals nor the transduction pathways that become activated in the oocyte are known. Therefore, the presence and the activity of candidate signaling pathways in growing murine oocytes were investigated. By immunoblotting, the MAP kinases, ERK1 and ERK2, as well as their activating kinase MEK, were detected in oocytes at all stages of growth. However, using a phospho-specific anti-ERK antibody, no

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14

Dalton, C. M. "Mitochondrial dynamics during mouse oocyte maturation." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1335718/.

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Mitochondria provide the primary source of ATP for the oocyte and pre-implantation embryo and undergo a number of redistributions during oocyte maturation which may be related to developmental competence. The experiments presented in this thesis aim to examine the changes in distribution and function of mitochondria during the transition from the germinal vesicle stage to the mature metaphase II arrested egg. Mitochondrial distribution was monitored throughout oocyte maturation and accumulation of mitochondria around the first meiotic spindle was observed. This was dependent on the activities

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15

Januschke, Jens. "MRNA localization in the Drosophila oocyte." Paris 7, 2005. http://www.theses.fr/2005PA077101.

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16

Plachynta, Maksym. "Studies on cryopreservation of zebrafish (Danio rerio) oocytes using controlled slow cooling." Thesis, University of Bedfordshire, 2007. http://hdl.handle.net/10547/622016.

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Cryopreservation of fish germ cells has important applications in aquaculture, conservation of endangered species and human genomic studies. Although investigations on cryopreservation of fish sperm and embryos have been carried out extensively, cryopreservation of fish oocytes has not been studied systematically. The objective of the present study was to develop successful cryopreservation protocol for zebrafish oocytes at temperature of liquid nitrogen (-196°C), or if unachieved, to investigate the limiting factors associated with fish oocytes cryopreservation. In this study, the effects of

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17

Amdani, Siti Nornadhirah. "The oocyte-activation factor, phospholipase C zeta (PLCζ) : clinical prognosis, diagnosis, and treatment of oocyte activation deficiency". Thesis, University of Oxford, 2018. https://ora.ox.ac.uk/objects/uuid:af4c4f98-497a-4666-9eec-a46bb579dd59.

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Oocyte activation deficiency (OAD) is an infertile condition observed in patients who have experienced recurrent total fertilisation failure (TFF) following intracytoplasmic sperm injection treatment. This condition was considered to be an idiopathic factor for a long time but strong clinical evidence now suggests that dysfunctional forms of phospholipase C zeta (PLCζ) may be predominant causative factors for OAD. Genetic contribution has played a role in patients suspected of having OAD, as four PLCζ exonic mutations have been discovered and characterised as being the cause of infer

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18

GARCIA, BARROS RODRIGO. "DEVELOPMENT OF NEW OOCYTE IN VITRO CULTURE STRATEGIES TO ENHANCE THE OUTCOME OF ASSISTED REPRODUCTIVE TECHNOLOGIES." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/809746.

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Fertility preservation has received unprecedented attention nowadays. In addition to cryopreservation and re-implantation of embryos, oocytes, and ovarian tissue pieces, in vitro culture system for follicles/oocytes has been considered an alternative strategy for fertility preservation. Reproduction strategies based on the recovery of oocytes' population from antral follicles are unsatisfactory, and the success of this approach has not exceeded 35% of embryos produced in vitro for over 30 years. The possibility of accessing the reserve of smaller follicles (primordial, secondary, and up to the

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19

Martínez, Marchal Ana. "Regulation of the oocyte pool in mammals." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/667797.

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Durant la oogènesi dels mamífers, les oogònies proliferen forman els anomenats cists. Les oogònies entren en meiosis progressant en la profase I i els cists es trenquen al mateix temps que es produeix una mort massiva perinatal dels oòcits. En la profase I, s’indueixen trencaments de doble cadena (DSBs) per tot el genoma, que son reparats per recombinació homòloga per a promoure la sinapsi dels cromosomes homòlegs. Existeixen diferents mecanismes que s’activen en resposta a errors en aquests processos i que aturen el cicle cel·lular i produeixen l’apoptosi de les cèl·lules danyades. La respost

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20

Carroll, John. "Cryopreservation and development of the mammalian oocyte /." Title page, contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phc319.pdf.

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21

McClellan, Kelly Anne. "Murine oocyte loss occurs during fetal development." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79047.

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Recently, the timing of oocyte loss during murine development has been brought into question as authors using mouse vasa homologue (MVH) as a germ cell marker did not observe a loss of oocytes during fetal life. Instead the major loss was observed in the days following birth, after chromosome pairing has occurred.<br>In this study the controversy was addressed by establishing a new and reliable method to quantify murine oocytes in meiotic prophase, as well as to determine the gestation age and meiotic prophase stage of oocyte loss. Earlier limitations were overcome through the use of Ge

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22

Davidson, Bryony Kathryn. "Raman spectroscopic investigation of the murine oocyte." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4641.

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Over recent years, the application of assisted reproductive techniques in the treatment of infertility has increased exponentially, yet these methodologies still remain inherently inefficient. It has long been established that the single greatest obstacle to improving the success of these treatments is determining the quality of the oocytes used. However, currently the methods available for oocyte assessment are mainly qualitative, and suffer due to a lack of standardisation. As such, the efficiency of fertility treatments could benefit from the introduction of a rigorous quantitative measure

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23

Huynh, J. R. "Oocyte determination and polarisation during Drosophila oogenesis." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604905.

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The antero-posterior and dorso-ventral axes of the <i>Drosophila</i> embryo are set up during oogenesis. These axes of polarity are the results of several symmetry-breaking steps that characterise the development of the <i>Drosophila</i> oocyte. During my PhD, I have studied two of these steps. Oocyte determination. During early oogenesis, one cell is selected to become the oocyte within a cyst of 16 germ cells. These 16 germ cells are all siblings and share the same cytoplasm. By using several oocyte-specific markers, I have found that there at least three different pathways to restrict the o

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24

McKenzie, Andy. "Modelling spiral waves in Xenopus laevis oocyte." Thesis, University of Canterbury. Mathematics and Statistics, 1997. http://hdl.handle.net/10092/6954.

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An investigation was made into the spiral waves solutions for the Atri et al model, a partial differential equation model for Ca²⁺ dynamics in the Xenopus laevis oocyte. Spiral wave solutions, both stable and unstable, were found to exist in the oscillatory regime for this model. The spiral wave solutions were found to have a period that decreased as the initial IP₃ bolus increased. Increasing the initial IP₃ bolus also lead to destabilisation of the spiral waves solutions. After the break up of spiral wave solutions complex spatio-temporal patterns occurred. In some cases spirals reformed aft

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25

Assidi, Mourad. "Oocyte competence and cumulus cells gene expression." Thesis, Université Laval, 2010. http://www.theses.ulaval.ca/2010/27679/27679.pdf.

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26

Hemmings, Karen Emily. "Cellular and molecular markers of oocyte quality." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445945.

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27

Sleep, Darrell. "Molecular analysis of Xenopus oocyte maternal RNA." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/11917.

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28

Mola, Choulia. "Identification of oocyte reprogramming factors and mechanisms." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/42492/.

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The ability of the oocyte to reprogram paternal chromatin is widely accepted. The oocyte cytoplasm has been reported to contain activities that alter the histone composition, demethylate and unwind highly methylated paternal DNA upon fertilization and lead to zygote formation. The same events are mimicked during the course of cell reprogramming, where somatic cells exposed to the oocyte environment acquire a pluripotent character. Amphibian oocytes have been widely used to study the reprogramming attributes of the female germ cells for over half a century. The size of amphibian oocytes renders

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29

Lee, Young Shin. "MATERNAL DETERMINANTS OF OOCYTE AND EMBRYO QUALITY." Diss., Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/111983.

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Molecular Biology and Genetics<br>Ph.D.<br>Oocyte quality plays a critical role in establishment of pregnancies, embryo development, implantation and the health of offspring. The oocyte provides maternal factors necessary for the initial development of its embryo during the period of transcriptional silence. Despite the consistent increase in number of couples seeking assisted reproductive treatments, oocyte quality still remains as an obstacle in successful fertility treatments and the mechanisms governing the quality of oocyte are poorly understood. Among various factors that may potentially

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30

Siordia, Jimena Carolina. "Analysis of Toxic Chemicals Affecting the Oocyte." Thesis, The University of Arizona, 2009. http://hdl.handle.net/10150/192989.

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31

Connolly, Amy. "Oocyte Meiotic Spindle Assembly in Caenorhabditis Elegans." Thesis, University of Oregon, 2014. http://hdl.handle.net/1794/18492.

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As in many organisms, Caenorhabditis elegans oocytes assemble bipolar meiotic spindles in the absence of centrosomes. While the assembly of the mitotic spindle in C. elegans has been studied in some detail, how the poles assemble in the absence of centrosomes remains poorly understood. In an ongoing screen for temperature-sensitive (TS), embryonic-lethal mutants, we have identified TS mutations in multiple genes required for oocyte meiotic spindle pole assembly. We have so far identified mutations in four genes: or1178ts in mei-1, which encodes the catalytic domain of the microtubule severing

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32

Zapater, Cardona Cinta. "Molecular physiology of a teleost oocyte aquaporin: evolution, regulation and role during oocyte hydration / Fisiología molecular de una acuaporina ovocitaria de teleósteos: Evolución, regulación y papel durante la hidratación del oocito." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/117374.

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In marine teleosts that spawn pelagic eggs (pelagophils), the process of oocyte hydration that occurs during meiosis resumption is a key physiological process for the survival of the eggs in the ocean. Previous studies have discovered the role of a teleost-specific aquaporin water channel (Aqp1b) during fish oocyte hydration, but direct experimental evidence for the function of Aqp1b in oocytes is still lacking. In addition, the molecular regulation of the Aqp1b-mediated mechanism remains poorly understood. In this context, the main objectives of the present thesis were to investigate the evol

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33

Yokoi, Hayato, and Kenjiro Ozato. "Injection of DNA into the medaka oocyte nucleus." Laboratory of Freshwater Fish Stocks Bioscience Center Nagoya University, 1995. http://hdl.handle.net/2237/13805.

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34

Alton, Michelle. "Control of the oocyte population in mouse ovaries." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81585.

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Oocyte loss and meiotic prophase progression was studied in XY sex-reversed and XO female mice, two mouse models that lack pairing between their sex chromosomes. An arrest at the pachytene stage of meiosis was not observed, nor was a significant loss of oocytes at this stage compared to normal XX control mice. Thus, it was concluded that a pairing checkpoint either does not exist in oocytes or is not as stringent as the one observed in males.<br>The effect of mutating the pro-apoptotic Bax molecule was studied at three distinct ages corresponding to the time when female germ cells are p

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35

Allsopp, Janet. "'Oocyte maturation in the Manila clam, Tapes philippinarum'." Thesis, Bangor University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357212.

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36

Ghafari, Fataneh. "Oocyte progression and death during first meiotic prophase." Thesis, University of Warwick, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409952.

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37

Ralph, John Hunter. "Factors affecting follicle and oocyte development in cattle." Thesis, University of Edinburgh, 1997. http://hdl.handle.net/1842/11889.

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The mechanisms governing development of mammalian oocytes are not well understood. Isolation and in vitro growth of immature cattle follicles will enable determination of the factors affecting bovine follicular development, have potential applications in assisted reproduction and provide a suitable model for studying human infertility. Intercommunication of the oocyte and somatic cells is necessary for normal oocyte and follicle development. Studies using systems where oocyte-somatic cell communication is preserved allows an accurate assessment of the factors affecting follicular development.

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38

Xie, Sancai. "Oocyte maturation and early embryo development in swine /." The Ohio State University, 1989. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487676261011605.

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39

Sartini, Becky Lynn. "Characterization of boar sperm plasma membrane candidate oocyte membrane fusion proteins and investigation of oocyte membrane binding sites in boar sperm populations /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2002. http://uclibs.org/PID/11984.

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40

Roura, Llerda Montserrat. "Fatty acids goat follicular fluid: effect on oocyte competence." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399336.

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Els àcids grassos (AAGG) són una important font d’energia pels oòcits en fase de creixement. Per tant, l’estudi del fluid fol·licular (FF) on aquests oòcits maduren és d’especial interès. En estudis previs, Romaguera i col. (2011) va concloure que els oòcits de fol·licles grans (≥ 3mm) eren més competents que els de fol·licles petits. A més, Catalá i col. (2015) van demostrar que hi havia una producció diferencial d’embrions entre les estacions de l’any, sent significativament més baixes a la tardor que a l’hivern. La nostra hipòtesi va ser que el perfil d’AAGG de cabres adultes i prepúbers

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41

Cornet, Bartolomé David. "Molecular determinants of human oocyte quality in assisted reproduction." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/667566.

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Infertility, defined by the World Health Organization (WHO) as the inability to conceive after a year of unprotected sex, is a disease that affects 1 in 9 couples of reproductive age worldwide. Most of these couples will only achieve pregnancy through assisted reproduction techniques. In recent decades, many improvements have been made in this field, but no method has been able to achieve 100% success. There are many variables that could affect the outcome of assisted reproduction cycles, one of the most important is the quality of the woman's oocytes. Maternal age is the most important factor

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42

Booth, Ronald A. "Signalling pathways controlling the initiation of Xenopus oocyte maturation." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6440.

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Xenopus laevis oocytes are physiologically arrested at the first meiotic prophase. Re-initiation of meiosis, or oocyte maturation, is triggered in vivo by progesterone, but can also be triggered by insulin and insulin-like growth factor-1 (IGF-1) in vitro. The mechanism by which these two very different hormones regulate the same physiological process is poorly understood. Chapter 2 describes my research that contributed to the characterization of the progesterone receptor responsible for inducing oocyte maturation. We demonstrated that the Xenopus progesterone receptor (xPR) is a dual functio

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43

Wang, Jing. "Function of protein kinase A in Xenopus oocyte maturation." Thesis, University of Ottawa (Canada), 2006. http://hdl.handle.net/10393/29377.

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Like most other vertebrate oocytes, oocytes from Xenopus laevis are physiologically arrested at the first meiotic prophase. Re-initiation of meiosis, or oocyte maturation, is triggered by progesterone. Progesterone-induced oocyte maturation is thought to involve inhibition of cAMP-dependent protein kinase (protein kinase A or PKA). However, changes in PKA activity in live oocytes have never been demonstrated. I have developed a novel approach to monitor endogenous PKA activity in live oocytes, by expressing a PKA-specific substrate in oocytes followed by monitoring its PKA phosphorylation sta

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44

Iatropoulou, Aikaterini. "Genesis of chromosomal abnormalities during oocyte growth and maturation." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408762.

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45

Davies, Mark Richard. "Nuclear receptors in Xenopus oocyte maturation and early development." Thesis, University of Warwick, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396851.

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46

Dingwall, C. "The accumulation of proteins in the Xenopus oocyte nucleus." Thesis, Open University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354967.

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The ability of proteins to accumulate in the nucleus has been studied by injecting nucleoplasmin and calf thymus histone H1 into the cytoplasm of Xenopus oocytes. Nucleoplasmin, the most abundant protein in the Xenopus oocyte nucleus is pentameric and proteolysis of the nuceloplasmin pentamer produces a relatively protease resistant 'core' molecule that cannot enter the nucleus after microinjection into the cytoplasm. The polypeptide domain ('lq tail') of each subunit removed by proteolysis was obtained as a discrete fragment and has the ability to accumulate in the nucleus. Partially cleaved

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47

Ilozue, Tagbo. "Cytoplasmic dynamics in the mouse oocyte and preimplantation embryo." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708499.

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48

Zhao, Tongtong. "Mechanisms of oocyte polarisation and axis formation in Drosophila." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610207.

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49

Ford, Nicola. "Interactions between translation initiation factors in the Xenopus oocyte." Thesis, University of Sussex, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413319.

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50

BUCHHOLZ, JANDA LEIGH. "DONOR FERTILITY AFTER PARTICIPATION IN AN OOCYTE DONATION PROGRAM." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1025724050.

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