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Journal articles on the topic 'OPD'

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Published: 4 June 2021
Last updated: 10 March 2023

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1

Cierpka, M. "OPD-2." Psychotherapeut 51, no. 2 (March 2006): 171–74. http://dx.doi.org/10.1007/s00278-006-0474-1.

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2

Ehrenthal, Johannes C., Ulrike Dinger, Henning Schauenburg, Lena Horsch, Reiner W. Dahlbender, and Benjamin Gierk. "Entwicklung einer Zwölf-Item-Version des OPD-Strukturfragebogens (OPD-SFK)/ Development of a 12-item version of the OPD-Structure Questionnaire (OPD-SQS)." Zeitschrift für Psychosomatische Medizin und Psychotherapie 61, no. 3 (September 2015): 262–74. http://dx.doi.org/10.13109/zptm.2015.61.3.262.

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3

Benecke, Cord, Miriam Henkel, Stephan Doering, Thorsten Jakobsen, Michael Stasch, Reiner Dahlbender, Sarah Alhabbo, and Johannes Zimmermann. "Der OPD-Konfliktfragebogen." Zeitschrift für Psychosomatische Medizin und Psychotherapie 64, no. 4 (December 5, 2018): 380–93. http://dx.doi.org/10.13109/zptm.2018.64.4.380.

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4

Cierpka, Manfred. "OPD und DKPM." PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie 56, no. 02 (February 2, 2006): 41. http://dx.doi.org/10.1055/s-2005-915437.

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5

Fliedl, Rainer, and Petra Katzenschläger. "Reliabilität und Konstruktvalidität der OPD-KJ Achsen: Struktur und Behandlungsvoraussetzungen – Vergleich OPD-KJ mit OPD-KJ-2." neuropsychiatrie 30, no. 3 (September 2016): 151–57. http://dx.doi.org/10.1007/s40211-016-0201-2.

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6

Ehrenthal, Johannes, Ulrike Dinger, Lena Horsch, Miriam Komo-Lang, Mathias Klinkerfuß, Tilman Grande, and Henning Schauenburg. "Der OPD-Strukturfragebogen (OPD-SF): Erste Ergebnisse zu Reliabilität und Validität." PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie 62, no. 01 (January 2012): 25–32. http://dx.doi.org/10.1055/s-0031-1295481.

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7

Shah, A. V. "ECT on OPD basis." Psychiatric Bulletin 10, no. 9 (September 1, 1986): 248. http://dx.doi.org/10.1192/pb.10.9.248-a.

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8

Zador, Imre. "ECT on OPD basis." Bulletin of the Royal College of Psychiatrists 11, no. 4 (April 1987): 131. http://dx.doi.org/10.1192/pb.11.4.131.

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9

Reid, Steve. "The Path to OPD." South African Family Practice 52, no. 6 (November 2010): 535. http://dx.doi.org/10.1080/20786204.2010.10874043.

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10

Shah, Anvil V. "ECT on OPD basis." Bulletin of the Royal College of Psychiatrists 10, no. 9 (September 1986): 248. http://dx.doi.org/10.1192/s0140078900028467.

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11

Elfianis, Rita, Joko Warino, Rosmaina Rosmaina, Suherman Suherman, and Zulfahmi Zulfahmi. "ANALISIS KEKERABATAN GENETIK TANAMAN PADI (Oryza sativa L.) DI KABUPATEN KAMPAR DENGAN MENGGUNAKAN PENANDA Random Amplified Polymorphic DNA (RAPD)." Jurnal Agroteknologi 11, no. 2 (February 21, 2021): 75. http://dx.doi.org/10.24014/ja.v11i2.10013.

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Rice is a cereal crop that belongs to the graminae family of high economic value, and is the main food for more than a portion of the world's population. This study aims to determine the relationship genetic of rice in Kampar by RAPD marker. Eight genotypes of rice from district in Kampar were amplified using eight primers (OPA 5, OPB 7, OPC 19, OPD 2, OPD 3, OPD 8, OPD 11, and OPD 13). The analysis of molecular data was performed by using NTSys pc -2.02 and GenAlex 6.1 . The results of the amplification of rice produced 48 loci with DNA band sizes obtained ranging from 350-1700 bp. The average percentage of polymorphic loci of the eight primers was 49.80%, where the highest percentage of polymorphic loci produced by OPA-7 primer was 75%, while the lowest polymorphic locus percentage was observed in OPD-13 primer which was 14.28%. The value of genetic distance between rice from Kampar in this study is in the range of 0.06 - 0.37. At a genetic distance of 0.79, rice plants can be grouped into two groups, namely the first group consisting of sokan and coku. The second group consisted of suntiong, korean , cupak putio, kuniong, jangguik, and cupak tenggi. The results of this study are expected to be taken into consideration in developing rice breeding strategies in the future.
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12

Mutawwab, Noer Panca, Mohamad Djasuli, and Muhammad Syam Kusufi. "Determinants The Quality of OPD Financial Statements (Empirical Study on OPD in Madura)." AFEBI Accounting Review 2, no. 02 (January 11, 2018): 121. http://dx.doi.org/10.47312/aar.v2i02.89.

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<p><em>There are still problems in the implementation of financial management, BPK finds as many as 10,154 and 15,434 issues containing the problems. In the acquisition of local government; The Local Government Financial Statements (LKPD) opinion Madura at year 2011-2015, only Pamekasan government increased, while Sampang and Sumenep consistently obtain Fair With Exceptions (WDP), and Bangkalan occurred a fall of LKPD opinion from Fair unqualified (WTP) to WDP. The objects of research are both the general chief and employees / financial section staff / accounting, treasurer and the author of financial statement in the Organization of Local Government (OPD) of Local Government in Madura. The used research method is quantitative method, while the sampling technique in this study is purposive sampling technique. The results of this research are the government </em><em>a</em><em>pparatus competence has a positive effect on the quality of OPD financial statement, the internal control system of government has a positive effect on the quality of OPD financial statement, the implementation of regional financial accounting system has a positive effect on the quality of OPD financial statement, the implementation of government accounting standards has a positive effect on the quality of OPD financial statement, ethic has a positive effect on the quality of OPD financial statement, experience has a positive effect on the quality of OPD financial statement.</em><em> </em><em></em></p><strong><em>Keywords: </em></strong><em>quality of financial statement, the Organization of Local Government (OPD)</em>
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13

Zhang, Ya-Xin, Shan-Shan Qu, Li-Hua Zhang, Yu-Yan Gu, Yi-Hao Chen, Zhi-Yong Huang, Meng-Hua Liu, et al. "The Role of Ophiopogonin D in Atherosclerosis: Impact on Lipid Metabolism and Gut Microbiota." American Journal of Chinese Medicine 49, no. 06 (January 2021): 1449–71. http://dx.doi.org/10.1142/s0192415x21500683.

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Gut microbiota has been proven to play an important role in many metabolic diseases and cardiovascular disease, particularly atherosclerosis. Ophiopogonin D (OPD), one of the effective compounds in Ophiopogon japonicus, is considered beneficial to metabolic syndrome and cardiovascular diseases. In this study, we have illuminated the effect of OPD in ApoE knockout (ApoE[Formula: see text] mice on the development of atherosclerosis and gut microbiota. To investigate the potential ability of OPD to alleviate atherosclerosis, 24 eight-week-old male ApoE[Formula: see text] mice (C57BL/6 background) were fed a high-fat diet (HFD) for 12 weeks, and 8 male C57BL/6 mice were fed a normal diet, serving as the control group. ApoE[Formula: see text] mice were randomly divided into the model group, OPD group, and simvastatin group ([Formula: see text]= 8). After treatment for 12 consecutive weeks, the results showed that OPD treatment significantly decreased the plaque formation and levels of serum lipid compared with those in the model group. In addition, OPD improved oral glucose tolerance and insulin resistance as well as reducing hepatocyte steatosis. Further analysis revealed that OPD might attenuate atherosclerosis through inhibiting mTOR phosphorylation and the consequent lipid metabolism signaling pathways mediated by SREBP1 and SCD1 in vivo and in vitro. Furthermore, OPD treatment led to significant structural changes in gut microbiota and fecal metabolites in HFD-fed mice and reduced the relative abundance of Erysipelotrichaceae genera associated with cholesterol metabolism. Collectively, these findings illustrate that OPD could significantly protect against atherosclerosis, which might be associated with the moderation of lipid metabolism and alterations in gut microbiota composition and fecal metabolites.
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14

P, Jayashree. "Sedation for OPD Procedures- Recommendations." Journal of Medical and Scientific Research 1, no. 1 (March 1, 2013): 37–39. http://dx.doi.org/10.17727/jmsr.2013/1-008.

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15

Born, Michael. "LISA Pathfinder: OPD loop characterisation." Journal of Physics: Conference Series 840 (May 2017): 012036. http://dx.doi.org/10.1088/1742-6596/840/1/012036.

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16

Lyles, Vincent. "Unwanted Romance in the OPD." Physiotherapy 83, no. 9 (September 1997): 504. http://dx.doi.org/10.1016/s0031-9406(05)65659-3.

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17

Jakobsen, Th, V. Albertini, A. Dieckmann, L. Forschner, D. Nitzgen, J. H. Obendiek, H. Sporn, D. Tabatabai, and K. von Ploetz. "Das OPD-Modul für Abhängigkeitserkrankungen." Suchttherapie 11, no. 04 (October 8, 2010): 183–88. http://dx.doi.org/10.1055/s-0030-1261873.

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18

Obbarius, Alexander, Nina Obbarius, Felix Fischer, Gregor Liegl, and Matthias Rose. "Evaluation der Faktorenstruktur und Konstruktvalidität der 12-Item Kurzversion des OPD-Strukturfragebogens (OPD-SFK) an psychosomatischen Patienten." PPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie 69, no. 01 (February 15, 2018): 38–48. http://dx.doi.org/10.1055/s-0043-125394.

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Zusammenfassung Einleitung Das Screening struktureller Einschränkungen der Persönlichkeit gilt zunehmend als wichtig für die Planung der stationären Behandlung, da hierdurch frühzeitig spezifische Behandlungspfade festgelegt werden können. Kürzlich wurde zu diesem Zweck der 12-Item Screening-Fragebogen zur OPD-Strukturachse (OPD-SFK) entwickelt und erste Ergebnisse zur Faktorenstruktur und Validität veröffentlicht. Das Ziel der aktuellen Studie bestand darin, den OPD-SFK außerhalb des Entwicklerteams an weiteren Stichproben zu validieren und Referenzwerte zur Verfügung zu stellen. Material und Methoden Die Datenerhebung erfolgte zwischen 2012 und 2016 in der psychosomatischen Ambulanz (N=565) und auf der psychosomatischen Station (N=670) der Charité – Universitätsmedizin Berlin. Um die Faktorenstruktur des OPD-SFK zu überprüfen wurden für beide Stichproben konfirmatorische Faktorenanalysen (CFA) durchgeführt. Zur Überprüfung der Konstruktvalidität wurde bei N=105 Patienten ein SKID-II-Interview durchgeführt und N=160 Patienten füllten die 90-Item Version des Narzissmusinventars (NI-90) aus. Zusätzlich wurde die psychische, soziale und körperliche Gesundheit anhand weiterer Instrumente erhoben. Bivariate Korrelationen wurden berechnet, um die Zusammenhänge zwischen diesen Instrumenten und dem OPD-SFK zu untersuchen. Ergebnisse Die CFAs ergaben eine gute bis zufriedenstellende Modellgüte für das vorgeschlagene Dreifaktorenmodell und sehr gute Werte für ein Bi-Faktor-Modell. Die Analysen zur Konstruktvalidität ergaben hohe positive Korrelationen zwischen dem OPD-SFK und dem dimensionalen Score des SKID-II-Interviews, den SKID-II-Interviews und dem NI-90 und bestätigten somit die konvergente Validität. Für die diskriminante Validität zeigten sich heterogene Ergebnisse: Mit einer Reihe von Instrumenten zeigten sich mittlere bis hohe Zusammenhänge, bspw. mit dem D-CAT (Depression), A-CAT (Angst), S-CAT (Stress) und PHQ-15 (somatische Symptome). Folgeanalysen zeigten, dass der OPD-SF Faktor Selbstwirksamkeit möglicherweise besonders von aktueller Depressivität und Angst beeinflusst wird. Die Unterschiede der einzelnen Korrelationen der Subskalen des OPD-SFK mit den anderen Instrumenten waren gering. Schlussfolgerung Der OPD-SFK scheint zum Screening struktureller Defizite geeignet. Allerdings werden auch andere Aspekte der Psychopathologie miterfasst, sodass während der klinischen Behandlung eine weitere Diagnostik der Persönlichkeitsstruktur, z. B. durch ein OPD-Interview zusätzlich sinnvoll scheint.
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19

Ślęzak, Andrzej, Sławomir Grzegorczyn, Kornelia M. Batko, Wiesław Pilis, and Robert Biczak. "Membrane Transport in Concentration Polarization Conditions: Evaluation of S-Entropy Production for Ternary Non-Electrolyte Solutions." Journal of Non-Equilibrium Thermodynamics 45, no. 4 (October 25, 2020): 385–99. http://dx.doi.org/10.1515/jnet-2020-0012.

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AbstractA model of the S-entropy production in a system with a membrane which separates non-electrolyte aqueous solutions was presented. The differences between fluxes in non-homogeneous and homogeneous conditions for volume and solute fluxes, respectively, are non-linear functions of the glucose osmotic pressure difference (OPD) in ranges dependent on the initial ethanol OPD. A decrease of ethanol OPD causes a shift of this range into the lower values of glucose OPD; this shift is also observed for negative values of glucose and ethanol OPDs. The coefficient of concentration polarization of the membrane as a function of glucose OPD has a sigmoidal shape. For suitably great negative values of glucose OPD this coefficient is very small, while for suitably high positive glucose OPD this coefficient is equal to 0.5. An increase of ethanol OPD at the initial moment causes a shift of this curve towards the direction of positive values of glucose OPD. In turn the S-entropy production in non-homogeneous conditions has low values for negative values of glucose OPD (convective range) while for suitably high positive glucose OPD it has greater values (diffusive and convective range). A change of ethanol OPD at the initial moment causes a shift of this curve along the horizontal axis.
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20

Ng, Terry L., Rustain Morgan, Tejas Patil, Anna E. Barón, and D. Ross Camidge. "The role of positron emission tomography fused with computed tomography (PET/CT) versus CT alone in detecting oligoprogressive disease (OPD) in oncogene-addicted non-small cell lung cancer (NSCLC) receiving tyrosine kinase inhibitor (TKI) therapy." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): e20683-e20683. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e20683.

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e20683 Background: OPD represents limited extra-central nervous system (eCNS) progression. In oncogene-addicted NSCLC, OPD can be treated with local ablative therapy to prolong TKI control. The impact of PET/CT vs CT to detect OPD at first eCNS progression has not been assessed previously. Methods: Patients with metastatic EGFR-mutant (EGFR-MT), ALK or ROS-1 rearranged (ALK+, ROS-1+) NSCLC with eCNS progression on a relevant TKI (2010-2016) were identified. Scan methodology at first eCNS progression was noted and progression was categorized as OPD using 2 definitions (≤ 2 or ≤ 4 progressing lesions) or non-OPD. Median time-to-progression (MTTP) was calculated from start of TKI to first eCNS progression. Data was analyzed using Chi squared and log rank tests as appropriate using p < 0.05 as significant. Results: Sixty-seven patients (EGFR-MT = 37, ALK+ = 28, ROS-1 = 2) were analyzable. OPD (≤ 2 lesions) occurred in 62.5% (20/32) noted by PET/CT vs. 54.3 % (19/35) by CT (p = 0.496). OPD (≤ 4 lesions) occurred in 84.4 % (27/32) noted by PET/CT vs. 65.7 % (23/35) by CT (p = 0.080). MTTP in PET/CT-detected OPD (≤ 2) (N = 20) was 332.5 days vs. 143 days in CT-detected OPD (N = 19) (p = 0.0092). MTTP in PET/CT-detected non-OPD ( > 2) (N = 12) was 185 days vs. 109 days in CT-detected non-OPD (N = 17) (p = 0.0503). MTTP in PET/CT-detected OPD (≤ 4) (N = 27) was 298 days vs. 143 days in CT-detected OPD (N = 23) (p = 0.0128). MTTP in PET/CT-detected non-OPD ( > 4) (N = 5) was 167 days vs. 104.5 days in CT-detected non-OPD (N = 12) (p = 0.1090). Conclusions: In this non-randomized retrospective study the proportion of OPD (≤ 2 or ≤ 4 progressing lesions) at first eCNS progression did not differ significantly for PET/CT vs. CT. MTTP was significantly longer for PET/CT vs CT detected OPD, but not for non-OPD progression. Potentially longer MTTP in the PET/CT OPD subgroup may reflect preselecting patients with disease difficult to detect by CT (e.g., bone/lymph node) which is more indolent. A prospective randomized study is required to assess the true impact of PET/CT vs CT on detecting OPD in oncogene-addicted NSCLC on TKI therapy.
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21

Nita, Ni Komang Norma, and Ni Luh Supadmi. "Pengaruh Pengendalian Internal, Integritas, Asimetri Informasi dan Kapabilitas Pada Kecurangan Akuntansi." E-Jurnal Akuntansi 28, no. 3 (September 12, 2019): 1819. http://dx.doi.org/10.24843/eja.2019.v28.i03.p12.

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This study aims to determine the effect of internal control, integrity, information asymmetry and capability on accounting fraud in OPD District X. The population used is 37 OPD. The sample in this study was the Head of the OPD, Secretary of the OPD, Financial Staff and Managers of each Service in District X with a total of 148 respondents. The method of determining the sample uses a purposive sampling method and data collection using a questionnaire. Data were analyzed using Linear Regression Analysis. Based on the results of the analysis show that internal control and integrity have a negative effect on accounting fraud. While the information asymmetry and capability variables have a positive effect on accounting fraud. For ODP District X in making decisions related to the existence of internal control, integrity, information asymmetry and capabilities in an organization so that this can affect the level of accounting fraud. Keywords : Internal control, integrity, information asymmetry, capability, accounting fraud.
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22

Patel, Priyanka, Nina Tunariu, and Alison Tree. "Prevalence of oligoprogression in metastatic hormone-resistant prostate cancer patients on androgen targeted therapies: Could targeted radiotherapy improve patient outcomes?" Journal of Clinical Oncology 39, no. 6_suppl (February 20, 2021): 110. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.110.

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110 Background: Androgen receptor-targeted therapies (ART) such as Abiraterone and Enzalutamide have shifted the management paradigm of metastatic castrate-resistant prostate cancer (mCRPC). These treatments are well-tolerated with less toxicities compared to chemotherapy, therefore methods to delay chemotherapy are beneficial to patients. Patients eventually become resistant to ARTs, and some patients will progress in a limited number of sites. This study investigated the prevalence of oligoprogressive disease (OPD) amenable to Stereotactic-body radiotherapy (SBRT). OPD is defined as ≤3 metastatic lesions which are progressing or new whilst all other sites of disease are well-controlled by ART. Methods: Retrospective analysis of electronic patient records and imaging studies of 95 patients treated with ART for mCRPC between April 2015 – 2017 from a single centre was undertaken. Data was analysed at the time of first tumour progression on ART. Results: The median (IQR) age of patients was 78.8 (74.4-83.6) years. OPD was found in 27 (28%) patients, 18 (19%) had lesions suitable for SBRT (Table). Seventeen (63%) patients were treated with abiraterone, 10 (27%) patients with enzalutamide. Median (IQR) time from starting ART to OPD was 16.4 (8.6-19.9) months. Five (19%) patients had 3 sites of OPD, 8 (29%) patients had 2 sites of OPD and 14 (52%) patients had 1 site of OPD. Nineteen patients continued ART beyond OPD for ≥3months. OPD was diagnosed using CT scan (56%), whole body diffusion-weighted MRI (22%), choline PET/CT (19%) and bone scan (3%). Six (22%) patients were treated with radiotherapy for OPD, 3 as participants of the TRAP trial (NCT03644303). Median time to subsequent progression after OPD for the 3 patients treated off trial with radiotherapy was 20.5 months. The OPD lesions treated with radiotherapy included the prostate (2 patients, 30 Gy in 5 and 24 Gy in 4 fractions) and para-aortic lymph node (1 patient, 30 Gy in 5 fractions). Median time to subsequent progression after OPD for those who did not receive radiotherapy was 6.4 months. There was no significant difference between median overall survival between patients with OPD and those who progressed with > 3 lesions (7 vs 9.2 years, P= 0.54). Ten (66%) patients who progressed after initial OPD on continuation of ART progressed with further OPD (≤3 lesions including original OPD lesion). Conclusions: OPD is prevalent in patients on ART for mCRPC. The most frequent site of OPD was in bone and majority of patients had only 1 site of OPD at presentation. These results identify a cohort of patients who may benefit from SBRT to maximise ART treatment. Fourteen (14%) patients met entry criteria for TRAP trial which is currently testing the role of SBRT to sites of OPD in mCRPC. [Table: see text]
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23

Dong, Wei, Zhen-Gen Liao, Guo-Wei Zhao, Xue-Jing Guan, Jing Zhang, Xin-Li Liang, and Ming Yang. "Reversal Effect of Oxypeucedanin on P-glycoprotein-mediated Drug Transport." Molecules 23, no. 8 (July 24, 2018): 1841. http://dx.doi.org/10.3390/molecules23081841.

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P-glycoprotein affects the transport of numerous drugs including chemotherapeutic drugs vincristine sulfate (VCR) and docetaxel (DTX), and is one of the main causes for multidrug resistance. Our previous studies have shown that oxypeucedanin (OPD) can enhance the intestinal transit of puerarin and VCR. However, the underlying mechanism is unclear. This study investigated the potential mechanism by which OPD improves P-gp-mediated drug transport. Molecular docking was performed to predict the binding force between OPD and P-gp and the contribution of OPD on P-gp activity. We observed the effect of OPD on the transport of VCR in MDCK-MDR1 cell monolayer and also measured the plasma pharmacokinetic parameters of DTX in the presence and absence of OPD by LC-MS/MS. Moreover, we further investigated the reversal mechanism of OPD on P-gp-mediated drug transport by determining the intracellular accumulation of Rhodamine-123 (Rh123) and P-gp ATPase activity as well as protein expression and mRNA level of P-gp. Our molecular docking results revealed that the binding force between OPD and P-gp was much lower than that between P-gp and verapamil (a P-gp substrate). The transport study in vitro indicated that OPD increased the flux of VCR across MDCK-MDR1 cell monolayer. The in vivo pharmacokinetic parameters data showed OPD increased the absorption of DTX. OPD activated P-gp ATPase activity and enhanced intracellular accumulation of Rh123 in MDCK-MDR1 cells. Western blotting and qRT-PCR outcomes indicated that OPD suppressed P-gp protein expression as well as downregulated P-gp mRNA level. Thus, OPD reverse P-gp-mediated drug transport via inhibition of P-gp activity and P-gp protein expression as well as downregulation of P-gp mRNA level. Our results suggest that OPD could reverse P-gp-mediated drug resistance in tumor cells.
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Xu, Huan-Hua, Zhen-Hong Jiang, Yu-Ting Sun, Li-Zhen Qiu, Long-Long Xu, Xiang-Lin Tang, Zeng-Chun Ma, and Yue Gao. "Differences in the Hemolytic Behavior of Two Isomers in Ophiopogon japonicus In Vitro and In Vivo and Their Risk Warnings." Oxidative Medicine and Cellular Longevity 2020 (December 14, 2020): 1–16. http://dx.doi.org/10.1155/2020/8870656.

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Ophiopogonin D (OPD) and Ophiopogonin D ′ (OPD ′ ) are two bioactive ingredients in Ophiopogon japonicus. Previously published studies have often focused on the therapeutic effects related to OPD’s antioxidant capacity but underestimated the cytotoxicity-related side effects of OPD ′ , which may result in unpredictable risks. In this study, we reported another side effect of OPD ′ , hemolysis, and what was unexpected was that this side effect also appeared with OPD. Although hemolysis effects for saponins are familiar to researchers, the hemolytic behavior of OPD or OPD ′ and the interactions between these two isomers are unique. Therefore, we investigated the effects of OPD and OPD ′ alone or in combination on the hemolytic behavior in vitro and in vivo and adopted chemical compatibility and proteomics methods to explain the potential mechanism. Meanwhile, to explain the drug-drug interactions (DDIs), molecular modeling was applied to explore the possible common targets. In this study, we reported that OPD ′ caused hemolysis both in vitro and in vivo, while OPD only caused hemolysis in vivo. We clarified the differences and DDIs in the hemolytic behavior of the two isomers. An analysis of the underlying mechanism governing this phenomenon showed that hemolysis caused by OPD or OPD ′ was related to the destruction of the redox balance of erythrocytes. In vivo, in addition to the redox imbalance, the proteomics data demonstrated that lipid metabolic disorders and mitochondrial energy metabolism are extensively involved by hemolysis. We provided a comprehensive description of the hemolysis of two isomers in Ophiopogon japonicus, and risk warnings related to hemolysis were presented. Our research also provided a positive reference for the development and further research of such bioactive components.
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25

Park, So Hyun, Ji-Young Hong, Hyen Joo Park, and Sang Kook Lee. "The Antiproliferative Activity of Oxypeucedanin via Induction of G2/M Phase Cell Cycle Arrest and p53-Dependent MDM2/p21 Expression in Human Hepatoma Cells." Molecules 25, no. 3 (January 23, 2020): 501. http://dx.doi.org/10.3390/molecules25030501.

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Oxypeucedanin (OPD), a furocoumarin compound from Angelica dahurica (Umbelliferae), exhibits potential antiproliferative activities in human cancer cells. However, the underlying molecular mechanisms of OPD as an anticancer agent in human hepatocellular cancer cells have not been fully elucidated. Therefore, the present study investigated the antiproliferative effect of OPD in SK-Hep-1 human hepatoma cells. OPD effectively inhibited the growth of SK-Hep-1 cells. Flow cytometric analysis revealed that OPD was able to induce G2/M phase cell cycle arrest in cells. The G2/M phase cell cycle arrest by OPD was associated with the downregulation of the checkpoint proteins cyclin B1, cyclin E, cdc2, and cdc25c, and the up-regulation of p-chk1 (Ser345) expression. The growth-inhibitory activity of OPD against hepatoma cells was found to be p53-dependent. The p53-expressing cells (SK-Hep-1 and HepG2) were sensitive, but p53-null cells (Hep3B) were insensitive to the antiproliferative activity of OPD. OPD also activated the expression of p53, and thus leading to the induction of MDM2 and p21, which indicates that the antiproliferative activity of OPD is in part correlated with the modulation of p53 in cancer cells. In addition, the combination of OPD with gemcitabine showed synergistic growth-inhibitory activity in SK-Hep-1 cells. These findings suggest that the anti-proliferative activity of OPD may be highly associated with the induction of G2/M phase cell cycle arrest and upregulation of the p53/MDM2/p21 axis in SK-HEP-1 hepatoma cells.
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Tertiyandini, Kamelia, Sucahyo Heriningsih, and Sriyono Sriyono. "PENGARUH SISTEM INFORMASI AKUNTANSI, KOMITMEN ORGANISASI, DAN SISTEM PENGENDALIAN INTERNAL TERHADAP KINERJA ORGANISASI PERANGKAT DAERAH (OPD) DI LINGKUNGAN PEMERINTAH DAERAH DAERAH ISTIMEWA YOGYAKARTA." Modus 34, no. 2 (September 19, 2022): 184–201. http://dx.doi.org/10.24002/modus.v34i2.5790.

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ABSTRACT This study aims to determine the effect of accounting information systems, organizational commitment and internal control systems on the performance of regional organizations (OPD) in the Yogyakarta Special Region Government. The population of this research is employees who are in 36 OPD within the Yogyakarta Special Region Government. The sampling technique used in this study is purposive sampling. This study uses primary data by conducting a survey through the distribution of questionnaires addressed to OPD in the Yogyakarta Special Region Government. Hypothesis testing in this study uses multiple linear regression analysis method. The results showed that the accounting information system and internal control system had an effect on the performance of OPD within the Yogyakarta Special Region Government, while organizational commitment had no effect on the performance of the OPD within the Yogyakarta Special Region Government. Keywords: accounting information system; organizational commitment; internal control system; OPD performance. ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh sistem informasi akuntansi, komitmen organisasi dan sistem pengendalian internal terhadap kinerja organisasi perangkat daerah (OPD) di lingkungan Pemerintah Daerah (Pemda) Daerah Istimewa Yogyakarta (DIY). Populasi dari penelitian ini adalah pegawai yang berada pada 36 OPD di lingkungan Pemda DIY. Teknik pengambilan sampel dalam penelitian ini menggunakan purposive sampling. Penelitian ini menggunakan data primer dengan cara melakukan survei melalui penyebaran kuesioner yang ditujukan kepada OPD di Pemda DIY. Pengujian hipotesis dalam penelitian ini menggunakan metode analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa sistem informasi akuntansi dan sistem pengendalian internal berpengaruh terhadap kinerja OPD di lingkungan Pemda DIY, sedangkan komitmen organisasi tidak berpengaruh terhadap kinerja OPD di lingkungan Pemda DIY. Kata kunci: sistem informasi akuntansi; komitmen organisasi; sistem pengendalian internal; kinerja OPD.
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Loske, Gunnar, Tobias Schorsch, Frank Rucktaeschel, Wolfgang Schulze, Burkhard Riefel, Vera van Ackeren, and Christian Mueller. "Open-pore film drainage (OFD): a new multipurpose tool for endoscopic negative pressure therapy (ENPT)." Endoscopy International Open 06, no. 07 (July 2018): E865—E871. http://dx.doi.org/10.1055/a-0599-5886.

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Abstract Background and study aims Endoscopic negative pressure therapy (ENPT) has been developed to treat gastrointestinal leakages. Up to now, ENPT has usually been performed with open-pore polyurethane foam drains (OPD). A big disadvantage of the OPDs is their large diameter. We have developed a new, small-bore open-pore film drainage (OFD). Herein we report our first experience in a case series of 16 patients. Patients and methods OFD is constructed with a drainage tube and a very thin double-layered open-pore drainage film (Suprasorb CNP, Drainage Film, Lohmann & Rauscher International, Germany). The distal end of the tube is wrapped with only one layer of film. OFD is placed into the gastrointestinal leakage site with common endoscopic techniques. The tube is connected to an electronic vacuum device and continuous negative pressure of –125 mmHg applied. Results From 2013 to 2016, 16 patients were treated with the new OFD device. In 10 patients, transmural intestinal defects (4 esophageal, 4 rectum/colon, 1 duodenal, 1 pancreatic cyst) were closed with ENPT in median time of 12 days (range 3 – 34 days). Five of the 10 patients were treated solely with OFD devices. In five patients ENPT started with ODP and changed to OFD when the cavity was shrunken to a channel with a small opening. In four patients postoperative gastric reflux was eliminated for 5 to 16 days. Conclusions Small-bore OFD opens up promising new treatment options within ENPT. OFD can be used in endoscopic closure management of intestinal leakages in the upper and lower gastrointestinal tract. Gastric reflux can be eliminated in an active manner. OFD can be inserted nasally. OFD may be an adequate substitute for OPD, especially when placement of the larger OPD is difficult.Meeting presentations: The authorsʼ experience was first reported in an oral presentation at the 46th Kongress der Deutschen Gesellschaft für Endoskopie und Bildgebende Verfahren in Mannheim (DGE-BV), 17. – 19.03.2016.
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Gokhale, Vijayashree, and Neha Chaudhary. "Concept of specialty - OPD for diabetes." Medical Journal of Dr. D.Y. Patil University 6, no. 1 (2013): 111. http://dx.doi.org/10.4103/0975-2870.108669.

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Holzer, Mike P., Susanne Goebels, and Gerd U. Auffarth. "Precision of NIDEK OPD-Scan Measurements." Journal of Refractive Surgery 22, no. 1 (November 1, 2006): S1021—S1023. http://dx.doi.org/10.3928/1081-597x-20061102-02.

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Dettmer, Barbara, and Hanns-Günter Wolf. "Was ist operationalisierte psychodynamische Diagnostik (OPD)?" Musiktherapeutische Umschau 29, no. 4 (December 2008): 380–83. http://dx.doi.org/10.13109/muum.2008.29.4.380.

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Bilke, Oliver, Veronika Diederichs-Paeschke, Christine Forkel, Ulrike Held, Cordula Jaletzke, and Bruno Stafski. "Psychoanalytisches Erstgespräch und OPD-KJ-Interview." Praxis der Kinderpsychologie und Kinderpsychiatrie 60, no. 1 (January 2011): 4–26. http://dx.doi.org/10.13109/prkk.2011.60.1.4.

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Sammet, Isa, Holger Himmighoffen, Johanna Brücker, Caroline Dreher, Cordula Olshausen Küchenhof, Fabian Wilmers, Andreas Wolf, Petra Zell, and Joachim Küchenhoff. "OPD in der Klinik: Ein Algorithmus für die Therapieplanung mit der Operationalisierten Psychodynamischen Diagnostik (OPD-2)." Zeitschrift für Psychosomatische Medizin und Psychotherapie 58, no. 3 (August 2012): 282–98. http://dx.doi.org/10.13109/zptm.2012.58.3.282.

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Huang, Jingwen, Jan D. Reinhardt, Ranran Dai, Pu Wang, and Min Zhou. "Validation of the brief international classification of functioning, disability, and health core set for obstructive pulmonary disease in the Chinese context." Chronic Respiratory Disease 16 (January 1, 2019): 147997311984364. http://dx.doi.org/10.1177/1479973119843648.

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In order to determine the validity of the International Classification of Functioning, Disability, and Health brief Core Set for Obstructive Pulmonary Disease (ICF-OPD) for the assessment of functioning and environmental factors in Chinese chronic OPD (COPD) patients, we conducted a cross-sectional study with a convenience sample of 100 COPD patients. Data were collected using common questionnaires for COPD patients (Modified British Medical Research Council Questionnaire, COPD Assessment Test, St George’s Respiratory Questionnaire (SGRQ)), the Brief ICF Core Set for OPD, and the comprehensive ICF checklist. All except one category of the Brief ICF-OPD Core Set were confirmed in our evaluation of its content validity, but there is a high prevalence of problems in 8 categories that were not considered in the Brief ICF-OPD Core Set. The functioning-related components of the Brief ICF-OPD Core Set largely performed similarly to SGRQ in terms of differentiating between patients with different disease severity. Moreover, high correlations between the Brief ICF-OPD Core Set overall score and component scores with the respective SGRQ scales and moderate correlations between ICF-OPD Core Set overall score and component scores and lung function parameters. This study largely confirmed content, known group, and convergent validity of the ICF-OPD.
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Stasch, Michael, Harald Forkel, Yeşim Reichert, Niels Schwindt, Johannes C. Ehrenthal, and Stephan Gingelmaier. "Eine Operationalisierte Psychodynamische Diagnostik (OPD) für Beziehungssysteme." Psychoanalytische Familientherapie 23, no. 2 (December 2022): 93–105. http://dx.doi.org/10.30820/1616-8836-2022-2-93.

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Die psychodynamischen Diagnoseinstrumente OPD (für Erwachsene) und OPD-KJ (für Kinder und Jugendliche) sind in der aktuell vorliegenden, zweiten Version mittlerweile im Rahmen der Richtlinien-Psychotherapie gut etabliert. Insbesondere in der psychiatrischen und psychotherapeutischen Behandlung von Kindern und Jugendlichen stellt der Einbezug des familiären Bezugssystems aber eine besondere Herausforderung dar, und oft fehlt es den psychodynamisch ausgebildeten Fachkräften an einem entsprechenden diagnostischen Modell. Diese Lücke soll durch die »OPD für Beziehungssysteme« geschlossen werden. Aktuell befindet sich dieses neue Instrument in Entwicklung. Die Achsen »Konflikt« und »Struktur« sind bereits ausgearbeitet und werden an dieser Stelle vorgestellt.
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Shrestha, Sirjana, and Pramod Bhatta. "Effect of Ayurvedic classical medicines in Kaphaja Kasa: A case report." Journal of Ayurveda Campus 1, no. 1 (September 12, 2020): 64–67. http://dx.doi.org/10.51648/jac.21.

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Kasa (Cough) is a common problem among patients visiting outdoor patient department (OPD) of Kayachikitsa at Ayurveda Campus and Teaching Hospital (ACTH). In the OPD, the treatment outcome of Kaphaja Kasa (chronic cough) is often less satisfactory. Chronic cough significantly hampers the overall quality of life of patient since it mainly affects the Pranavaha Shrotas (respiratory system). This is a case report of a 42 years old lady presented with Kaphaja Kasa at ACTH and was treated successfully with Classical Ayurvedic medicines.
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Saxena, Stuti. "Open public data (OPD) and the Gulf Cooperation Council (GCC): challenges and prospects." Contemporary Arab Affairs 10, no. 2 (April 1, 2017): 228–40. http://dx.doi.org/10.1080/17550912.2017.1297565.

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This paper seeks to assess the nature and scope of open data in government (OPD/open public data) in the Gulf Cooperation Council (GCC) countries of Bahrain, Kuwait, Qatar, Oman, Saudi Arabia and the United Arab Emirates (UAE). Following a qualitative approach, OPD portals of GCC countries are being studied besides seeking inputs from secondary data sources which are relevant in providing theoretical understanding of OPD. The paper shows that OPD in the GCC countries is in its nascent stage and little academic interest has been shown in this area. Future research should highlight the prospects of OPD implementation in the GCC countries given their strategic importance for many reasons. To ascertain that the OPD implementation gathers pace in the GCC countries, governments need to make more robust strategies in terms of physical and research infrastructure for better data analytics and utility. Hitherto, there has been no study covering the significance and implications of OPD in a GCC context; this is the first study to undertake this as its research theme. Furthermore, academic research on OPD in the GCC countries is lacking; the present study seeks to fill this gap.
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Schrobildgen, Christian, Kirstin Goth, Ruth Weissensteiner, Olga Lazari, and Klaus Schmeck. "Der OPD-KJ2-SF – Ein Instrument zur Erfassung der Achse Struktur der OPD-KJ-2 bei Jugendlichen im Selbsturteil." Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie 47, no. 5 (September 1, 2019): 428–40. http://dx.doi.org/10.1024/1422-4917/a000667.

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Zusammenfassung. Die Erfassung der Strukturdimensionen nach OPD-KJ-2 ist neben ihrer therapeutischen Relevanz vor dem Hintergrund ihrer inhaltlichen Nähe zu gegenwärtig diskutierten dimensionalen Herangehensweisen in der Diagnostik von Persönlichkeitsstörungen im DSM-5 und in der ICD-11 von hoher Aktualität. Im Rahmen dieser Studie erfolgte eine Evaluation der psychometrischen Gütekriterien des neu entwickelten Fragenbogens OPD-KJ-2-SF zur Erfassung der Strukturdimensionen im Jugendalter. Die Untersuchung wurde anhand einer gemischten klinischen und nichtklinischen Stichprobe (N = 589) durchgeführt. Der OPD-KJ2-SF zeigte sehr gute psychometrische Kennwerte mit guten Skalenreliabilitäten von .87 bis .98 Cronbachs Alpha auf Gesamt- und Hauptskalenebene. Alle Hauptskalen diskriminierten hoch signifikant mit Effektstärken (d) von 1.4 bis 1.6 zwischen den Schüler_innen und Patient_innen mit Persönlichkeitsstörungen. Der OPD-KJ2-SF erscheint als ein reliables und valides Instrument zur Erfassung von strukturellen Beeinträchtigungen im Jugendalter.
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Deichmann, Steffen, Louisa Bolm, Kim Honselmann, Ulrich Wellner, Hryhoriy Lapshyn, Tobias Keck, and Dirk Bausch. "Perioperative and Long-term Oncological Results of Minimally Invasive Pancreatoduodenectomy as Hybrid Technique – A Matched Pair Analysis of 120 Cases." Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie 143, no. 02 (April 2018): 155–61. http://dx.doi.org/10.1055/s-0043-124374.

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Abstract Background Laparoscopic pancreatoduodenectomy is a highly challenging procedure. The aim of this study was to analyse post-operative morbidity and mortality as well as long term overall survival in patients undergoing hybrid LPD, as compared to open pancreaticoduodenecomy (OPD) in a single surgeon series. Methods Patients undergoing pancreatoduodenectomy (PD) in the period from 2000 to 2015 were identified from a prospectively maintained database. All LPD procedures were performed by one specialised pancreatic surgeon (TK). Patients were matched 1 : 1 for age, sex, BMI, ASA, histological diagnosis, pancreatic texture and portal venous resection (PVR). All LPD procedures were performed as hybrid LPD – combining laparoscopic resection and open reconstruction via mini laparotomy. Results A total of 549 patients were identified, including 489 patients in the OPD group and 60 patients in the LPD group. 60 patients were identified who underwent LPD between 2010 and 2015 versus 60 OPD patients operated in the same period. Median overall operation time was shorter in the LPD group than with OPD patients (LPD 352 vs. OPD 397 min; p = 0.002). Overall transfusion units were lower in the LPD group (LPD range 0 – 4 vs. OPD range 0 – 11; p = 0.032). Intensive care unit stay (LPD 1 vs. OPD 6 d; p = 0.008) and overall hospital stay (OHS: LPD 14 vs. OPD 18 d; p = 0.012) were shorter in the LPD groups than in the OPD group. As regards postoperative complications, LPD was associated with reduced rates of clinically relevant grade B/C postoperative pancreatic fistula (LPD 15 vs. OPD 36%; p = 0.036) and grade B/C delayed gastric emptying (LPD 8 vs. OPD 20%; p = 0.049). A total of 56 patients were diagnosed with malignant disease. The number of harvested lymph nodes and R0-resection rates were equal for LPD and OPD patients. LPD patients showed a trend to improved median overall survival (LPD mean 56 months vs. OPD mean 48 months; p = 0.056). Conclusion Hybrid LPD is a safe procedure associated with a reduction in clinically relevant postoperative complications and allows faster recovery. Long term oncological outcome of hybrid LPD for malignant disease is equal to that with the standard open approach.
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Payong, Yohanes. "Layanan Informasi Publik Dan Pengaduan Masyarakat Pemerintah Kota Kupang." Jurnal Inovasi Kebijakan 5, no. 1 (May 25, 2020): 13–33. http://dx.doi.org/10.37182/jik.v5i1.46.

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Informasi semakin dibutuhkan oleh banyak orang untuk mengembangkan kepribadian pada lingkungan sosialnya. Layanan terhadap infpormasi publik dan pengaduan masyarakt menjadi hak pokok bagi warga negara. Amanat UU No 14 Tahun 2008 Tentang Keterbukaan Informasi Publik, terdapat beberapa jenis informasi sebagai berikut: informasi yang wajib disediakan dan diumumkan secara berkala, informasi yang wajib diumumkan secara serta merta, informsi yang tersedia setiap saat. Organisasi Perangkat Daerah (OPD) pada Pemerintah Kota Kupang belum sepenuhnya melaksanakan amanat UU tersebut diatas. Berdasarkan unit atau bagian yang menangani informasi publik, OPD pada Pemerintah Kota Kupang terdapat 35% (OPD) menyatakan sudah ada namun masih berada di salah satu bagian tertentu, dan belum secara spesifik pada salah satu unit. Sedangkan unit yang ditugaskan untuk menagani pengaduan masyarakat terdapat 32% (OPD) yang sudah ada unit/bagian namun berada pada bidang/bagian tertentu. Terkait dengan layanan informasi kepada masyarakat mayoritas OPD 48% menggunakan melalui sosial mediauntuk menyampaikan layanan informasi kepada masyarakat. Sedangkan menggunakan website hanya 2 OPD, hal ini disebabkan minimnya OPD yang memiliki website atau portal. Sementara media yang digunakan untuk memantau progress atau perkembangan layanan pengaduan masyarakat terdapat penggunaan media 38% OPD menggunakan email/telpon. Rata-rata layanan informasi publik dengan nilai 54,7% dengan kategori kriteria “Tidak Baik”. Untuk itu diperlukan adanya peningkatan kinerja OPD terkait hal tersebut. Berdasarkan hasil analisis gap terdapat nilai harapan lebih besar dari persepsi, terdapat kriteria kesenjangan adalah Tidak Puas dengan nilai antara 29 sampai 40. Hal ini menunjukan bahawa semua kondisi OPD terkait layanan informasi publik maupun pengaduan masyarakat tidak sesuai dengan yang diharapkan. Demikian halnya dengan media untuk akses informasi publik dan layanan pengaduan masih jauh dari harapan.
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Chhabra, Shibba Takkar, Gurleen Kaur, Riya Aggarwal, Namita Bansal, Harsh Kishore, Mamta Goyal, Anshuman Gupta, et al. "Outpatient Attendance in COVID Pandemic Lockdown: An Observational Study." Indian Journal of Cardiovascular Disease in Women 8 (March 1, 2023): 18–24. http://dx.doi.org/10.25259/ijcdw_17_2023.

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Objectives: The objectives of this study were to analyze the profile of outpatient department (OPD) attendance of a tertiary care hospital during pre- and post-pandemic lockdown period. Materials and Methods: All consecutive patients presenting to OPD from August 1, 2019 to November 23, 2020 were included in the study. The sample was divided into Zone R (Regular domain) and Zone L (Lockdown domain). Zone L was divided into three groups A, B, and C; representing attendance to be <30%, 30–60%, and >60% of previous (i.e., Zone R), respectively. The patient gender, intradepartmental, and inter departmental OPD attendance data were collected and analyzed. Results: n = 428,322 patients attended the OPD in the study period. 301,586 patients presented in Zone R and 126,736 presented in Zone L (P = 0.000). Zone L recorded an OPD attendance drop to 42% of Zone R. The least attended an OPD (Group A) was ophthalmology, ENT, dermatology, surgery, and orthopedics versus highest attendance (Group C) was noticed in emergency OPD and oncology with a moderate decline in the rest (P = −0.00, 0.00, and 0.00, respectively). Both male and female attendance in the OPD showed a decline; however, the gender divide was apparent with significantly low women attendance in all the departments (P = 0.00). Conclusion: OPD attendance showed a significant reduction in COVID lockdown era hitting the non-emergent medical branches the most. The gender divide significantly widened with less female attendance recorded in most OPDs in pandemic lockdown. Apt administrative measures could prove fruitful by an improved OPD attendance and its psychosocial implications to a society with less disease burden.
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Siddavattam, Dayananda, Syed Khajamohiddin, Bramanandam Manavathi, Suresh B. Pakala, and Mike Merrick. "Transposon-Like Organization of the Plasmid-Borne Organophosphate Degradation (opd) Gene Cluster Found in Flavobacterium sp." Applied and Environmental Microbiology 69, no. 5 (May 2003): 2533–39. http://dx.doi.org/10.1128/aem.69.5.2533-2539.2003.

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ABSTRACT Several bacterial strains that can use organophosphate pesticides as a source of carbon have been isolated from soil samples collected from diverse geographical regions. All these organisms synthesize an enzyme called parathion hydrolase, and in each case the enzyme is encoded by a gene (opd) located on a large indigenous plasmid. These plasmids show considerable genetic diversity, but the region containing the opd gene is highly conserved. Two opd plasmids, pPDL2 from Flavobacterium sp. and pCMS1 from Pseudomonas diminuta, are well characterized, and in each of them a region of about 5.1 kb containing the opd gene shows an identical restriction pattern. We now report the complete sequence of the conserved region of plasmid pPDL2. The opd gene is flanked upstream by an insertion sequence, ISFlsp1, that is a member of the IS21 family, and downstream by a Tn3-like element encoding a transposase and a resolvase. Adjacent to opd but transcribed in the opposite direction is an open reading frame (orf243) with the potential to encode an aromatic hydrolase somewhat similar to Pseudomonas putida TodF. We have shown that orf243 encodes a polypeptide of 27 kDa, which plays a role in the degradation of p-nitrophenol and is likely to act in concert with opd in the degradation of parathion. The linkage of opd and orf243, the organization of the genes flanking opd, and the wide geographical distribution of these genes suggest that this DNA sequence may constitute a complex catabolic transposon.
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Juliantara, I. Wayan Ady, Sariyasa Sariyasa, and I. Made Gede Sunarya. "Factors Affecting the Implementation of e-Surat Applications at Regional Apparatus Organizations in Tabanan Regency." Journal of Computer Networks, Architecture and High Performance Computing 5, no. 1 (February 4, 2023): 198–209. http://dx.doi.org/10.47709/cnahpc.v5i1.2070.

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The development of information technology has given birth to many new innovations, such as the e-Surat application which can help the administrative process of electronic service manuscripts at the OPD (Regional Apparatus Organization) in Tabanan Regency. The implementation of the e-Surat application on OPD in Tabanan Regency is still not optimal, there are factors that affect the implementation of the e-Surat application on OPD in Tabanan Regency. The model or method that is considered appropriate for analyzing and understanding the factors that can affect the implementation of the e-Surat application on OPD in Tabanan Regency is the TOE framework that will analyze the implementation of the e-Surat application on OPD in Tabanan Regency in terms of technology, organization and environment aspects. Data analysis techniques use multiple linear regression analysis. The results of the data analysis show that: (1) technological variables have a positive and significant effect on the implementation of e-Surat applications in OPD in Tabanan Regency, (2) organizational variables have a positive and significant effect on the implementation of e-Surat applications in OPD in Tabanan Regency and (3) environmental variables have a positive and significant effect on the implementation of e-Surat applications in OPD in Tabanan Regency.
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Ziai, Kasra, Ronald Sahyouni, Omid Moshtaghi, Kimberly Vu, Khodayar Goshtasbi, Yaser Ghavami, Lauren Lee, Harrison W. Lin, and Hamid R. Djalilian. "An Analysis of the Open Payment Database in Neurotology." Otolaryngology–Head and Neck Surgery 158, no. 2 (February 2018): 319–22. http://dx.doi.org/10.1177/0194599817742357.

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Since the introduction of the Sunshine Act in 2010 and Open Payments Database (OPD) in 2013, a significant amount of data has been collected on physicians and the payments received through ties with pharmaceutical and medical device companies. To date, a study within the field of otology and neurotology using data from the 2015 OPD has not been conducted. As such, we assessed the validity and accuracy of OPD information for otologists and neurotologists (O&Ns). Of the 126 physicians listed as O&Ns in the OPD, 25 were actually general otolaryngologists, and 1 was a cardiologist. In addition, 88 O&Ns were misclassified by the OPD as general otolaryngologists. A total of 1156 payments, summing $1,966,204, were made to O&Ns as a whole, with 646, 507, and 3 payments classified as general, research, and ownership/investment interests, respectively. Analysis of OPD data for O&Ns demonstrates a significant financial relationship between O&N physicians and industry, as well as noteworthy inaccuracies in the OPD that likely affect other subspecialties.
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Gomez, Maria Faye Anne S., Leonid D. Zamora, Paul John Ablaza, Melvin Remulla Marcial, and Leilani B. Mercado-Asis. "Target-Oriented Clinical Skill Enhancement (TOCSE) Builds Up Confi dence of Fourth-Year Medical Students During First-Time Patient Encounter: An Effective Bridging Tool After Online Didactic Undergraduate Classes During the COVID-19 Pandemic." Journal of Medicine, University of Santo Tomas 6, S1 (December 7, 2022): S114—S125. http://dx.doi.org/10.35460/2546-1621.2022-sp15.

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Background and Objective: Teaching clinical skills to undergraduate medical students has brought significant challenges during the COVID-19 pandemic. Patient discussion utilized hypothetical cases from history taking to diagnosis and management. Further, everything was delivered online. Target-Oriented Clinical Skill Enhancement (TOCSE) is a teaching and learning tool that integrates the basic medical sciences, such as anatomy, physiology, pathology, microbiology, and pharmacology, at the clinical level. TOCSE has been proven to improve the clinical performance of fourth-year medical students. However, clinical confidence remains an issue, especially for medical students on pure online mode of learning during the pandemic. Therefore, this study was undertaken to determine if TOCSE also facilitates the development of confidence in the clinical performance of 4th-year medical students during the first-time patient encounter after online undergraduate classes. Methods: Eight-item Clinical Performance Confidence Scale survey was performed at three (3) time points of fourth-year medical student’s rotation in the Department of Medicine: (1) prior to the deployment to the outpatient department (Pre-OPD), (2) after the first-time patient encounter without TOCSE workshop (Post-OPD no TOCSE), and (3) after the patient encounter with TOCSE workshop (Post-OPD with TOCSE). Mean and standard deviations were used to summarize the confidence level of the 4th-year medical students, based on the 10-point differential scale being 0 as not confident at all and 10 as very confident. Wilcoxon Signed Rank assessed improvements of confidence level from Pre-OPD to Post-OPD. Effect sizes were also calculated to compare the improvement in the items. All statistical tests were performed in SPSS version 26.0. P-values less than 0.05 indicate a significant increase in the confidence level of 4th-year medical students. Results: There is a significant increase in the clinical confidence of 4th-year medical students from Pre-OPD to Post-OPD no TOCSE (mean ± SD: 6.32 ± 1.02 to 7.06 ± 0.95, p<0.001). Comparing the eight items between Pre-OPD and Post-OPD with no TOCSE, performing a complete physical examination has the most remarkable improvement. Further, there is a significant increase in the clinical confidence of 4th-year medical students from Post-OPD no TOCSE to Post-OPD with TOCSE (mean ± SD: 7.06 ± 0.95 to 7.51 ± 0.89, p<0.001). The performance of a complete history-taking has the most considerable improvement (7.29 + 1.03 to 7.89 + 1.01, p<0.001). Correspondingly, the most significant increase in the clinical confidence of 4th-year medical students was seen among the Post-OPD with TOCSE compared to their Pre- OPD confidence scores (mean ± SD: 6.32 ± 1.02 to 7.51 ± 0.89, p<0.001). Among the eight items between Pre-OPD and Post-OPD with TOCSE confidence scores, the item on performing a complete physical examination has the most remarkable improvement (5.67 ± 1.37 to 7.20 ± 1.22, p<0.001), closely followed by performing a complete history-taking (6.53 ± 1.19 to 7.89 ± 1.01, p<0.001). The most significant improvements in clinical confidence were seen in all the items in the Post-OPD with TOCSE than in the Post-OPD with no TOCSE versus Pre-OPD confidence scores. In addition, with TOCSE, the number of medical students who scored 7.50 and above was amplified more than 3 times (17.4% to 58.7%, p<0.001, Pre-OPD vs. Post-OPD with TOCSE, respectively). Conclusion: Target-Oriented Clinical Skill Enhancement (TOCSE) effectively builds up confidence during first-time patient encounters among fourth-year medical students taught online with hypothetical cases during their undergraduate classes. Key words: Target-Oriented Clinical Skill Enhancement, clinical confidence, clinical skill, fourth-year medical students, medical undergraduate challenge, online teaching in COVID-19 pandemic
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45

Schneider, Gudrun, Till Mendler, Gereon Heuft, and Markus Burgmer. "Validität der Konfliktachse der Operationalisierten Psychodynamischen Diagnostik (OPD-1) - empirische Ergebnisse und Folgerungen für die OPD-2." Zeitschrift für Psychosomatische Medizin und Psychotherapie 54, no. 1 (February 2008): 46–62. http://dx.doi.org/10.13109/zptm.2008.54.1.46.

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Heuft, Gereon, Thorsten Jakobsen, Reinholde Kriebel, Wolfgang Schneider, and Gerd Rudolf. "Potenzial der Operationalisierten Psychodynamische Diagnostik (OPD) für die Qualitätssicherung/ Operationalized Psychodynamic Diagnostic (OPD) – Potential for Quality Assurance." Zeitschrift für Psychosomatische Medizin und Psychotherapie 51, no. 3 (July 2005): 261–76. http://dx.doi.org/10.13109/zptm.2005.51.3.261.

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47

Schüßler, Gerhard, Markus Burgmer, Elmar Mans, Gundrun Schneider, Reiner Dahlbender, and Gereon Heuft. "Neurotische Konfliktsystematik - Grundlagen der Konfliktdiagnostik (OPD-2)/ Neurotic conflict systematics – the fundamentals of conflict diagnostics (OPD-2)." Zeitschrift für Psychosomatische Medizin und Psychotherapie 52, no. 1 (July 2006): 23–38. http://dx.doi.org/10.13109/zptm.2006.52.1.23.

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48

Sasegbon, Ayodele, Laura O’Shea, and Shaheen Hamdy. "Examining the relationship between sepsis and oropharyngeal dysphagia in hospitalised elderly patients: a retrospective cohort study." Frontline Gastroenterology 9, no. 4 (June 2, 2018): 256–61. http://dx.doi.org/10.1136/flgastro-2018-100994.

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IntroductionElderly people are recognised to be at increased risk of oropharyngeal dysphagia (OPD), the causes of which are multifactorial. Our aim was to identify if sepsis is associated with OPD in the elderly during hospitalisation in the absence of known other risk factors for OPD.MethodsA hospital electronic database was searched for elderly patients (≥65 years) referred for assessment for suspected dysphagia between March 2013 and 2014. Exclusion criteria were age <65 years, pre-existing OPD or acute OPD secondary to acute intracranial event, space-occupying lesion or trauma. Data were collected on factors including age, sex, comorbidities, existing OPD, sepsis, microbiology, recovery of OPD and medication. Sepsis was defined as evidence of a systemic inflammatory response syndrome with a clinical suspicion of infection.ResultsA total of 301 of 1761 screened patients referred for dysphagia assessment met the inclusion criteria. The prevalence of sepsis and subsequent OPD was 16% (51/301). The mean age was 83 years (median 81 years). The most common comorbidity was dementia (31%). The majority (84%) failed to recover swallowing during their hospital stay, 12% had complications of aspiration and 35% died. The most common source of sepsis was from the chest (55%). Other factors contributing to the risk for dysphagia included delirium (22%) and neuroactive medication (41%). However, 10% of patients had sepsis and subsequent OPD without other identified risk factors.ConclusionThe prevalence of sepsis and subsequent dysphagia is significant and should be taken into account in any elderly person in hospital with new-onset OPD without other predisposing risk factors.
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Septiani, Reni, and Rani Eka Diansari. "Apakah ketaatan aturan akuntansi akan mengurangi kecenderungan kecurangan akuntansi?" Journal of Business and Information Systems (e-ISSN: 2685-2543) 1, no. 1 (June 28, 2019): 1–8. http://dx.doi.org/10.36067/jbis.v1i1.7.

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The purpose of this research is to determine the effect of internal control, information asymmetry, and compliance with accounting rules on the tendency of accounting fraud in OPD of Yogyakarta City. This is a quantitative research with purposive sampling technique. The sample was all of OPD in Yogyakarta City. The data were collected by using questionnaires in OPD of Yogyakarta City. The data was analized by the multiple regression method. The results of the study show that internal control and information asymmetry have no significant effects on the tendency of accounting fraud in OPD of Yogyakarta City. The compliance with accounting rules have significant effects on the tendency of accounting fraud in OPD of Yogyakarta City.
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50

Yoo, Daegwang, Ki Byung Song, Jong Woo Lee, Kyungyeon Hwang, Sarang Hong, Dakyum Shin, Dae Wook Hwang, et al. "A Comparative Study of Laparoscopic versus Open Pancreaticoduodenectomy for Ampulla of Vater Carcinoma." Journal of Clinical Medicine 9, no. 7 (July 13, 2020): 2214. http://dx.doi.org/10.3390/jcm9072214.

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Several studies have compared laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD) in patients with periampullary carcinoma; however, only a few studies have made such a comparison on patients with ampulla of Vater cancer (AVC). We compared the perioperative and oncologic outcomes between LPD and OPD in patients with AVC using propensity-score-matched analysis. A total of 359 patients underwent PD due to AVC during the study period (76 LPD, 283 OPD). After propensity score matching, the LPD group showed significantly longer operation time than did the OPD group (400.2 vs. 344.6 min, p < 0.001). Nevertheless, the LPD group had fewer painkiller administrations (8.3 vs. 11.1, p < 0.049), fewer Grade II or more severe postoperative complications (15.9% vs. 34.8%, p = 0.012), and shorter postoperative hospital stays (13.7 vs. 17.3 days, p = 0.048), compared with the OPD group. There was no significant difference in recurrence-free outcomes and overall survival between the two groups (p = 0.754 and 0.768, respectively). Compared with OPD, LPD for AVC had comparative oncologic outcomes with less pain, less postoperative morbidity, and shorter hospital stays. LPD may serve as a promising alternative to OPD in patients with AVC.
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