Relevant bibliographies by topics / Operational matrix of differentiation

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  2. Dissertations / Theses
  3. Books
  4. Book chapters
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Academic literature on the topic 'Operational matrix of differentiation'

Author: Grafiati
Published: 3 June 2025
Last updated: 19 July 2025

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Journal articles on the topic "Operational matrix of differentiation"

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Sharma, Bhuvnesh, Sunil Kumar, M. K. Paswan, and Dindayal Mahato. "Chebyshev Operational Matrix Method for Lane-Emden Problem." Nonlinear Engineering 8, no. 1 (2019): 1–9. http://dx.doi.org/10.1515/nleng-2017-0157.

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AbstractIn the this paper, a new modified method is proposed for solving linear and nonlinear Lane-Emden type equations using first kind Chebyshev operational matrix of differentiation. The properties of first kind Chebyshev polynomial and their shifted polynomial are first presented. These properties together with the operation matrix of differentiation of first kind Chebyshev polynomial are utilized to obtain numerical solutions of a class of linear and nonlinear LaneEmden type singular initial value problems (IVPs). The absolute error of this method is graphically presented. The proposed framework is different from other numerical methods and can be used in differential equations of the same type. Several examples are illuminated to reveal the accuracy and validity of the proposed method.
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SPARIS, PANAGIOTIS D., and SPYRIDON G. MOUROUTSOS. "The operational matrix of differentiation for orthogonal polynomial series." International Journal of Control 44, no. 1 (1986): 1–15. http://dx.doi.org/10.1080/00207178608933579.

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Li, Yuanlu, Chang Pan, Xiao Meng, Yaqing Ding, and Haixiu Chen. "Haar Wavelet Based Implementation Method of the Non–integer Order Differentiation and its Application to Signal Enhancement." Measurement Science Review 15, no. 3 (2015): 101–6. http://dx.doi.org/10.1515/msr-2015-0015.

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Abstract Non–integer order differentiation is changing application of traditional differentiation because it can achieve a continuous interpolation of the integer order differentiation. However, implementation of the non–integer order differentiation is much more complex than that of integer order differentiation. For this purpose, a Haar wavelet-based implementation method of non–integer order differentiation is proposed. The basic idea of the proposed method is to use the operational matrix to compute the non–integer order differentiation of a signal through expanding the signal by the Haar wavelets and constructing Haar wavelet operational matrix of the non–integer order differentiation. The effectiveness of the proposed method was verified by comparison of theoretical results and those obtained by another non–integer order differential filtering method. Finally, non–integer order differentiation was applied to enhance signal.
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Jabbar A. Eleiwy. "Indirect Algorithm for Solving Variation Problems." Journal of the College of Basic Education 18, no. 73 (2023): 77–84. http://dx.doi.org/10.35950/cbej.v18i73.9624.

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In this paper, an approximate indirect method to solve some variational problems is proposed in terms of shifted Legendre polynomials. The operational matrix of differentiation for shifted Legendre polynomials is first derived. Using the operational matrix of differentiation, the variational problems are reduced to the solution of system of algebric equations with unknown shifted Legendre coefficients. Numerical example illustrates the efficiency, simplicity and accuracy of the proposed method.
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Guimarães, Osvaldo, José Roberto C. Piqueira, and Marcio Lobo Netto. "Direct Computation of Operational Matrices for Polynomial Bases." Mathematical Problems in Engineering 2010 (2010): 1–12. http://dx.doi.org/10.1155/2010/139198.

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Several numerical methods for boundary value problems use integral and differential operational matrices, expressed in polynomial bases in a Hilbert space of functions. This work presents a sequence of matrix operations allowing a direct computation of operational matrices for polynomial bases, orthogonal or not, starting with any previously known reference matrix. Furthermore, it shows how to obtain the reference matrix for a chosen polynomial base. The results presented here can be applied not only for integration and differentiation, but also for any linear operation.
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Bataineh, A. Sami, A. K. Alomari, and I. Hashim. "Approximate Solutions of Singular Two-Point BVPs Using Legendre Operational Matrix of Differentiation." Journal of Applied Mathematics 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/547502.

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Exact and approximate analytical solutions of linear and nonlinear singular two-point boundary value problems (BVPs) are obtained for the first time by the Legendre operational matrix of differentiation. Different from other numerical techniques, shifted Legendre polynomials and their properties are employed for deriving a general procedure for forming this matrix. The accuracy of the technique is demonstrated through several linear and nonlinear test examples.
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Pandey, Rajesh K., and Narayan Kumar. "Solution of Lane–Emden type equations using Bernstein operational matrix of differentiation." New Astronomy 17, no. 3 (2012): 303–8. http://dx.doi.org/10.1016/j.newast.2011.09.005.

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Pandey, Rajesh K., Narayan Kumar, Abhinav Bhardwaj, and Goutam Dutta. "Solution of Lane–Emden type equations using Legendre operational matrix of differentiation." Applied Mathematics and Computation 218, no. 14 (2012): 7629–37. http://dx.doi.org/10.1016/j.amc.2012.01.032.

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Tohidi, Emran, and Mohammad Shirazian. "Numerical Solution of Linear HPDEs Via Bernoulli Operational Matrix of Differentiation and Comparison with Taylor Matrix Method." Mathematical Sciences Letters 1, no. 1 (2012): 61–70. http://dx.doi.org/10.12785/msl/010108.

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Ezz–Eldien, Samer S., Ali H. Bhrawy, and Ahmed A. El–Kalaawy. "Direct numerical method for isoperimetric fractional variational problems based on operational matrix." Journal of Vibration and Control 24, no. 14 (2017): 3063–76. http://dx.doi.org/10.1177/1077546317700344.

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In this paper, we applied a direct method for a solution of isoperimetric fractional variational problems. We use shifted Legendre orthonormal polynomials as basis function of operational matrices of fractional differentiation and fractional integration in combination with the Lagrange multipliers technique for converting such isoperimetric fractional variational problems into solving a system of algebraic equations. Also, we show the convergence analysis of the presented technique and introduce some test problems with comparisons between our numerical results with those introduced using different methods.
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Dissertations / Theses on the topic "Operational matrix of differentiation"

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Price, R. C. "Sparse matrix optimisation using automatic differentiation." Thesis, University of Hertfordshire, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379908.

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Nyqvist, Jennifer. "Operational technology definition and differentiation : In the context of operational systems in Sweden." Thesis, Högskolan i Skövde, Institutionen för informationsteknologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-18752.

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ICS, short for Industrial Control Systems, can be a part of the electrical and water supplies among others, which are important instances for society. This all resides in the realm of Operational technology, abbreviation OT. Due to technological development, Information Technology i.e. IT is introduced and merged into the realm of industrial systems, because of society’s increasing dependencies on digital infrastructures and services.ICS and Supervisory Control and Data Acquisition (SCADA) systems are rather well known and reputable. In the realm of OT, there’s a range of different systems, and ICS itself encompasses a range of process automation technologies, such as SCADA systems and Distributed Control Systems (DCS) among others.This paper aims to try to define and differentiate a distinct boundary of systems without any connection to IT and can be considered purely OT, if they exist at all. This by conducting an interview with people working for governmental agencies with an eminent amount of experience in the realm of OT. What kind of systems are currently in operation today that don’t fit into the realm of ICS, do they exist at all and how do they work?The definition and differentiation of OT may indicate a subset of systems and components, and terminologies of systems in the OT-realm are misused, indicating a lack of insight in this realm of industrial systems.
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Lochter, André. "Control of neuronal differentiation by extracellular matrix constituents /." [S.l.] : [s.n.], 1993. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10325.

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Richardson, Lucy Elizabeth. "Extracellular matrix cues for mesenchymal stem cell differentiation." Thesis, Royal Veterinary College (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444369.

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Kurth, Ina. "Hematopoietic Stem Cell Differentiation inside Extracellular Matrix functionalized Microcavities." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-68614.

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The bone marrow (BM) niche provides hematopoietic stem (HSC) and progenitor cells with many exogenous cues that tightly regulate homeostasis. These cues orchestrate cellular decisions, which are difficult to dissect and analyze in vivo. This thesis introduces a novel in vitro platform that permits systematic studies of BM-relevant factors that regulate homeostasis. Specifically, the role of 3D patterned adhesion ligands and soluble cytokines were studied in a combinatorial fashion. Analysis of human HSC differentiation and proliferation at both population and single cell level showed synergistic and antagonistic effects of adhesion- and cytokine-related signals. Those effects were dependent on the cytokine concentration and the distribution and number of adhesion ligands. The aim of this thesis was to model the in vivo bone marrow with its porous 3D structure and different sized niche compartments using a microcavity culture carrier. The developed culture system presented extracellular matrix (ECM) adhesion ligands to the HSCs in various defined dimensions ranging from single- to multi-cell capacity. The 3D open well geometry of the microcavity carriers also allowed HSCs to freely explore different scenarios including homing, migration, adhesion, or suspension. Furthermore, the developed setup offered straightforward accessibility to analytical methods like cytometry and quantitative microscopy. Single cell analysis of adherent HSCs showed decreased DNA synthesis and higher levels of stem cell marker expression within single cell microcavities under low cytokine conditions . This effect was reflected in a decline of proliferation and differentiation with decreasing microcavity size. When the cytokine concentration was increased2 beyond physiological levels the inhibitory effect on proliferation and differentiation due to single-cell-microcavity adherence was diminished. This result highlighted the fine balance between adhesion related and soluble cues regulating HSC fate. Within small microcavities more adhesion related receptors were engaged due to the 3D character of the culture carrier compared to multi-cell wells or conventional 2D cell culture plates. This study demonstrated that adhesion-related signal activation leads to reduced proliferation and differentiation. This geometry-based effect could be reversed by increased cytokine supplementation in the culture media. For plane substrates, HSCs attachment to fibronectin or heparin initiated early cell cycle entry compared to non-adherent cells during the initial 24h. Cytokine supplemented media favored integrin activation that induced fast adhesion, ultimately leading to early cell cycle activation. However, after prolonged cell culture the system balanced itself with a lower cycling rate of adherent versus non-adherent HSCs. Furthermore, HSCs within the 3-dimensionality of the microcavities cycled less than 2D adherent cells. These findings additionally supported the above stated idea of limited HSC proliferation as a consequence of more adhesion-related signals overwriting cytokine driven expansion. To complement the various in vitro studies, an in vivo repopulation study was performed. Cultured HSCs derived from single cell microcavities outperformed freshly isolated HSCs in a competitive repopulation assay, indicating that carefully engineered substrates are capable of preserving stem cell potential. Overall the reported findings provide a promising in vitro culture strategy that allows the stem cell field to gain a better understanding of the impact of distinct exogenous signals on human HSCs, which discloses new concepts for the wide scientific community working towards tissue engineering and regenerative medicine<br>Die Homöostase der Hämatopoietischen Stamm- und Vorläuferzellen (HSC) in der Knochenmark Nische wird von einer Vielzahl exogener Faktoren gezielt reguliert. Diese Faktoren orchestrieren intrazelluläre Vorgänge, deren in vivo Analyse kompliziert ist. Die vorliegende These widmet sich einem neuen biotechnologischen Ansatz, der systematische Studien von Knochenmark-relevanten Faktoren ermöglicht. Im Speziellen wurde die Rolle 3D-präsentierter Zell Adhäsionsliganden in Kombination mit verschiedenen Konzentrationen löslicher Zytokine untersucht. Die Auswertung der Proliferation und Differenzierung von humanen HSC auf Einzelzell- und Populationsebene offenbarte die synergistischen und antagonistischen Effekte von Adhäsions- und Zytokinsignalen in ihrer Abhängigkeit von der Verteilung und der Anzahl von Adhäsionsliganden sowie der Zytokinkonzentration. Um die poröse Struktur des Knochenmarks in vivo-ähnlich darzustellen, wurde eine Zellkultur Plattform mit Mikrokavitäten verschiedenster Dimensionen von Multi- bis Einzelzellgröße entwickelt und mit Molekülen der extrazellulären Matrix beschichtet. Die Vorteile dieser Plattform liegen in der offenen 3D-Geometrie dieses mikrokavitäten Kultursystems, die den Zellen ermöglichte verschiedene Wachstumsbedingungen bezüglich Homing, Migration, Adhäsion oder Suspension frei zu erkunden. Das leicht zugängliche Setup eignete sich zudem hervorragend für die zytometrische Analyse der Zellen oder die quantitative Mikroskopie. Die Einzelzellanalyse adhärenter HSC ergab eine Reduktion von DNA Synthese und eine höhere Expression von Stammzelloberflächenfaktoren innerhalb der Einzelzell-Mikrokavitäten bei niedrigen Zytokinkonzentrationen . Dieser Effekt spiegelte sich auch auf Populationsebene in verminderter Proliferation und Differenzierung mit abnehmender Größe der Mikrokavitäten wider. Wurde die Zytokinkonzentration jedoch weit über physiologische Bedingungen erhöht, verminderte sich der Effekt (reduzierte DNA Synthese und höhere Stammzellfaktorexpression) beschrieben für die Einzelzellmikrokavitäten. Dieses Ergebnis verdeutlicht die empfindliche intrazelluläre Balance, vermittelt durch Adhäsionsignale und löslichen Faktoren, die das Verhalten von HSCs regulieren. Aufgrund des 3D-Charakters des Zellkulturträgers wurden innerhalb kleiner Mikrokavitäten mehr Adhäsionsrezeptoren ringsum die Zelle aktiviert. Dieser Vorteil gegenüber den Multizellkavitäten oder der herkömmlichen 2D–Zellkultur ermöglichte eine hohe Anzahl adhäsionsvermittelter Signale mit entsprechend höherer Proliferations-inhibitorischer Wirkung. Je höher die Konzentration der Zytokine war, desto stärker erfolgte die Stimulation der Proliferation und Differenzierung. Auf 2D Substraten, initiierte Adhäsion zu Fibronektin und Heparin innerhalb der ersten 24h einen frühen Zell-Zyklus-Start im Gegensatz zu nicht adhärenten Zellen. Die Zytokine im Zellmedium förderten die Integrin Aktivierung, was zu einer schnellen Zelladhäsion führte. Die Adhäsionsrezeptoren wiederum kooperieren mit Zytokinrezeptoren im Zellinneren und begünstigten damit einen zeitigeren Zell-Zyklus- Start. Allerdings stellte sich danach ein Gleichgewicht im Kultursystem ein, wobei weniger adhärente Zellen als nicht-adhärente Zellen den Zellzyklus durchliefen. Des Weiteren war die Zellzyklusrate innerhalb von 3D Mikrokavitäten niedriger verglichen mit herkömmlichen 2D Substraten. Diese Ergebnisse bestätigen ferner obenstehende These, dass Zytokin-induzierte Zellexpansion durch erhöhte Zelladhäsions-vermittelte Signale überschrieben wird. Um die in vitro Studien zu komplettieren wurde ein in vivo Repopulationsversuch durchgeführt. HSC kultiviert auf Einzel-Zell-Mikrokavitäten übertrafen frisch isolierte Konkurrenz-Zellen in einem kompetitiven Repopulationsversuch. Dieses erste Ergebnis zeigt, dass sich der Zellgröße entsprechende Biomaterialien für die erfolgreiche Stammzell-Kultur eignen. Die Ergebnisse dieser Arbeit bieten eine vielversprechende in vitro Zellkulturstrategie, die ein besseres Verständnis der Einflüsse von exogenen Signalen auf HSC erlaubt und damit eine Grundlage für neue Erkenntnisse in Richtung erfolgreicheres Tissue Engineering und klinische Anwendungen im Bereich der regenerativen Medizin bildet
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Al-Jallad, Hadil. "Role of transglutaminase enzymes in osteoblast differentiation and matrix deposition." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106326.

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Bone formation is an osteoblast-mediated process that is controlled by systemic factors such as hormones, growth factors and local cues that arise from the extracellular matrix (ECM). Bone ECM is elaborated by osteoblasts and therefore they can control their own activity. The ultimate goal of bone matrix formation is to elaborate an extracellular network, consisting mainly of fibronectin and collagen type I, that is capable of mineralizing and forming a strong tissue with appropriate tensile and elastic properties. This thesis describes studies that link transglutaminases (TGs), the protein cross-linking enzymes to type I collagen matrix deposition, osteoblast differentiation and bone formation. Findings here show that MC3T3-E1 osteoblasts require TG-activity for differentiation and proper production of collagenous matrices. We also show that osteoblasts produce two transglutaminase enzymes, transglutaminase 2 (TG2) and Factor XIIIA (FXIIIA), which are both expressed during osteoblast differentiation. The work further defines the roles of the two TGs in osteoblasts and shows that FXIIIA is the main TG-enzyme with transamidating activity in osteoblasts' ECM. Production of FXIIIA is induced during osteoblast differentiation and is externalized to the cell surface, then secreted to the ECM. TG2 was mainly found on the cell surface of osteoblasts with no transamidating activity; however, it is co-localized with FXIIIA on the cell surface. Studies conducted with chemical inhibitors, TG-substrates and activity probes suggest that TG-activity is required for osteoblast differentiation at three different levels. First, by positively affecting microtubule dynamics, delivery and fusion of secretory vesicles carrying cellular collagen type I to the plasma membrane. Second, by promoting fibronectin matrix deposition and collagen type I secretion. And third, by stabilizing the interaction between fibronectin and collagen type I in the ECM. Furthermore, we demonstrated that tubulin and fibronectin are candidate substrates for FXIIIA in osteoblasts. In summary, our studies are the first to describe FXIIIA transglutaminase expression in osteoblasts in vitro and in vivo, and first to link it to collagen secretion and osteoblast differentiation. Furthermore, these studies were the first to suggest a role for cellular FXIIIA in microtubule dynamics. We conclude that transglutaminase activity arising from FXIIIA can regulate osteoblast differentiation affecting extracellular matrix deposition.<br>La formation et le développement de l'os est un processus complexe dirigé par les ostéoblastes. Contrôlés par des hormones systémiques, des cytokines et d'autres facteurs locaux, les ostéoblastes sécrètent et assemblent la matrice extracellulaire (MEC) des tissus osseux. L'aboutissement de ce processus sera la génération d'un réseau extracellulaire constitué notamment de la fibronectine et du collagene de type I qui va se minéraliser en formant le tissu dur de l'os avec d'excellent propriétés mécaniques. Cette thèse présente des études liées aux transglutaminases (TGs) – une classe des enzymes responsables de la polymérisation (cross-linking) des protéines et d'autres composée biomacromoléculaires - en relation avec le collagène de type I secrété pendant l'élaboration de la MEC, la différentiation des ostéoblastes et l'élaboration du tissu osseux. Les principaux résultats de ces études portent sur l'observation que l'activité polymérisante de la TG est un facteur crucial pour la différentiation des cellules ostéoblastiques MC3T3-E1 et pour la production normale de la matrice collagénique. Un résultat essentiel de la présente recherche porte sur la découverte que les ostéoblastes synthétisent deux types d'enzymes TG, i.e. la transglutaminase 2 (TG2) et le facteur XIIIA (FXIIIA), qui sont tous les deux secrétés pendant la différentiation des ostéoblastes. Les résultats suivants éclaircirent les rôles des deux enzymes TG (TG2 et FXIIIA) dans l'activité des ostéoblastes en montrant que c'est le FXIIIA qui est l'enzyme TG dominante avec une activité de transamidation importante dans la MEC des ostéoblastes. FXIIIA est produit pendant la différentiation des ostéoblastes en s'externalisant vers la surface des cellules pour être par la suite sécrété dans la MEC. L'enzyme TG2 a été localisé seulement à la surface des cellules osteoblastiques. Même si le TG2 a été trouvé colocalisé avec le FXIIIA à la surface des cellules, aucune activité de transamidation n'est identifiée pour le TG2. Des études comportant des inhibiteurs chimiques, de substrats TG et de sondes d'activité TG suggèrent que l'activité TG est nécessaire pour la différentiation des ostéoblastes sur trois plans distincts, à savoir : (i) par une action bénéfique sur la dynamique des microtubules, l'acheminement et la fusion des vésicules sécrétoires qui transportent le collagène I cellulaire vers la membrane plasmatique; (ii) par l'accélération du dépôt de la matrice de fibronectine et la sécrétion du collagène de type I; (iii) par la stabilisation de l'interaction de la fibronectine avec le collagène I dans la MEC. De plus, nous avons démontré que la tubuline and la fibronectine ce sont de candidats substrat pour le facteur FXIIIA dans les ostéoblastes. En résumé, notre recherche décrit pour la première fois l'expression de l'enzyme transglutaminase FXIIIA dans les ostéoblastes, tant in vitro qu'in vivo, en corrélant l'expression du FXIIIA à la sécrétion et la différentiation des ostéoblastes. De plus, notre étude est la première en attribuant un rôle au facteur FXIIIA relative à la dynamique des microtubules. On conclut de notre étude que l'activité transglutaminase du facteur FXIIIA exerce une influence décisive dans les processus de différentiation des ostéoblastes avec un effet régulateur crucial à la sécrétion et au dépôt de la matrice extracellulaire.
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Amin, H. D. "Effects of enamel matrix derivative components on PDL cell differentiation." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1322447/.

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Previous studies have reported that the adult periodontal ligament (PDL) may contain progenitor/stem cells that function as precursors for periodontal tissue regeneration, although the ability of this population to differentiate into the multiple lineages present in the PDL is not yet certain. In addition, although Enamel Matrix Derivative (EMD; Emdogain®), derived from the enamel matrix of developing teeth) has been used extensively to help re-build new periodontal tissue, its effect on bone regeneration remains inconclusive and its effect on PDL blood vessels and nerve cell development not yet known, because it comprises a heterogeneous mixture of proteins. EMD has recently been separated into two main fractions: Fraction C, containing proteins < 6 kDa (mainly the tyrosine-rich amelogenin peptide TRAP); and Fraction A, containing proteins > 6 KDa (including the full-length amelogenin, sheathlins and a leucine-rich amelogenin peptide LRAP). The present study examined the effects of EMD Fractions on multi-lineage differentiation pathays of PDL cells in vitro. The results of the present study have shown that that Fraction C and Fraction A differentially regulate multilineage specification of PDL cells. Thus, Fraction C was found to up-regulate chondrogenic, vasculogenic, angiogenic, neurogenic and gliogenic genes and ‘terminal’ differentiation, whereas Fraction A was found to stimulate osteogenic genes and terminal osteogenic differentiation in vitro; both fractions suppressed adipogenesis. Moreover, the TRAP and LRAP peptides of Fraction C and Fraction A, respectively, were found to be at least partly responsible for the differential activities of these two fractions. In addition, at least some components in these EMD Fractions bound to and were internalized into PDL cells, most probably by receptor-mediated endocytosis. These findings thus demonstrate that the PDL contains cells with multi-lineage differentiation potential and that the components of EMD have differential effects on the diverse activities on the heterogeneous cells present in the PDL.
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Delaine-Smith, Robin M. "Mechanical and physical guidance of osteogenic differentiation and matrix production." Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/3691/.

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Summary Tissue engineering and regenerative medicine strategies until now have mostly relied on static culture using chemical stimulation to induce cell differentiation. However, these strategies neglect the dynamic environment in which cells reside in the body where they are surrounded by a chemically and physically well-defined threedimensional (3D) topography. Not only does this environment control cellular differentiation, but its structure also determines the mechanical function of that tissue. Alongside physical cues, external mechanical forces play an essential role in the homeostasis of many tissues, particularly bone. In order to develop tissue engineered constructs that are suitable for implantation, it may be important to incorporate these essential cues into pre-culture methods and in order to do this, a better understanding of the cellular responses is required. The main aim of this research was to understand how physical and mechanical cues affect cell behaviour, differentiation and matrix production, with particular emphasis on osteogenesis and collagen organisation. In order to achieve this, electrospun scaffolds were fabricated with controllable fibre orientation for studies involving fibroblast matrix organisation, and the affect on the differentiation of osteoprogenitor cells. Short bouts of tensile loading were conducted using a previously established bioreactor model for conditioning collagen-producing cells. A simple rocking platform method for subjecting cells to fluid-flow was also investigated for its potential to enhance osteogenesis and collagen organisation. This system was further used to study the role of the primary cilium for the mechanotransduction of bone cells. The overall goal was to understand how to manipulate cell differentiation and matrix production in order to develop a more suitable construct with correct tissue structure in a rapid manner. Monitoring of the major structural matrix protein collagen was achieved using the minimally-invasive technique of second harmonic generation, which was optimised. Electrospun scaffolds with a random architecture caused cells to deposit matrix in a similar random manner, however highly aligned scaffolds caused deposited collagen to orientate in the fibre direction giving superior tensile properties. Further to this, random fibres appeared to be more favourable for the differentiation of osteoprogenitor cells than highly aligned substrates. 9 Short bouts of tensile stimulation of collagen producing cells on 3D substrates caused an increase in collagen deposition. Another stimulation method, a simple rocking platform, created oscillatory fluid shear stress (FSS) suitable for stimulation of osteogenic cells and enhanced collagen organisation. Further to this, human dermal fibroblasts could be induced to form a mineralised matrix when cultured in osteogenic media, which was further enhanced with FSS. It was also demonstrated that this simple rocking system could be used to test a wide variety of loading parameters. Finally, rocking was used to examine the role of the primary cilium in the load-induced mineral deposition response of bone cells. When mature bone cells were subjected to FSS, primary cilia shortened in length and removal of primary cilia resulted in loss of the load-induced matrix response suggesting that primary cilia are mechanosensors in bone cells.
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Helwig, Bryan Glen. "Neuronal differentiation of stem cells derived from human umbilical cord matrix /." Search for this dissertation online, 2003. http://wwwlib.umi.com/cr/ksu/main.

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Xu, Yanyi. "Matrix Property-Controlled Stem Cell Differentiation for Cardiac and Skeletal Tissue Regeneration." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1440161684.

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Books on the topic "Operational matrix of differentiation"

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Jameson, Leland. On the spline-based wavelet differentiation matrix. Institute for Computer Applications in Science and Engineering, 1993.

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Jameson, Leland. On the Daubechies-based wavelet differentiation matrix. Institute for Computer Applications in Science and Engineering, 1993.

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Center, Langley Research, ed. On the Daubechies-based wavelet differentiation matrix. National Aeronautics and Space Administration, Langley Research Center, 1994.

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Jameson, Leland. On the spline-based wavelet differentiation matrix [microform]. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Jameson, Leland. On the spline-based wavelet differentiation matrix [microform]. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Jameson, Leland. On the spline-based wavelet differentiation matrix [microform]. National Aeronautics and Space Administration, Langley Research Center, 1993.

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Jameson, Leland. On the wavelet optimized finite difference method. Institute for Computer Applications in Science and Engineering, 1994.

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Kesoretskikh, Ivan, and Sergey Zotov. Landscape vulnerability: concept and assessment. INFRA-M Academic Publishing LLC., 2019. http://dx.doi.org/10.12737/1045820.

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The monograph presents a methodology for assessing the vulnerability of landscapes to external influences. A comparative analysis of the concepts of "stability", "sensitivity", "vulnerability" in relation to natural complexes. An overview of existing methods for assessing the vulnerability of natural complexes is presented. The author's method of assessing the vulnerability of landscapes to anthropogenic impacts is described. The methodology is based on: selection and justification of criteria for assessing the vulnerability of landscapes; preparation of a parametric matrix and gradation of assessment criteria in accordance with the developed vulnerability classes; calculation of weighting factors of vulnerability assessment parameters; selection of optimal territorial operational unit for landscape vulnerability assessment. The method is implemented in the GIS environment "Assessment of vulnerability of landscapes of the Kaliningrad region to anthropogenic impacts", created by the authors using modern geoinformation products. The specificity of spatial differentiation of different landscapes in terms of vulnerability to anthropogenic impacts at the regional and local levels is revealed. It is stated that the use of the methodology for assessing the vulnerability of landscapes to anthropogenic impacts and its integration into the system of nature management will ensure a balanced account of geoecological features and environmental priorities in territorial planning.&#x0D; It is of interest to specialists in the field of rational nature management, environmental protection, spatial planning.
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Patrick, Beck, and Füger Erik, eds. The Supply Chain Differentiation Guide: A Roadmap to Operational Excellence. Springer Berlin Heidelberg, 2013.

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service), SpringerLink (Online, ed. Fractional Differentiation Inequalities. Springer-Verlag New York, 2009.

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Book chapters on the topic "Operational matrix of differentiation"

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Harville, David A. "Matrix Differentiation." In Matrix Algebra From a Statistician’s Perspective. Springer New York, 1997. http://dx.doi.org/10.1007/0-387-22677-x_15.

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Harville, David A. "Matrix Differentiation." In Matrix Algebra: Exercises and Solutions. Springer New York, 2001. http://dx.doi.org/10.1007/978-1-4613-0181-3_15.

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Nichelatti, Michele. "Matrix Differentiation." In TELe-Health. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-81709-0_22.

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Engel, Andreas. "Differentiation". У Taylorentwicklung, Jacobi-Matrix, ∇, δ(x) und Co. Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/978-3-662-59752-1_1.

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Wakefield, Jon. "Differentiation of Matrix Expressions." In Springer Series in Statistics. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0925-1_13.

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Dhrymes, Phoebus J. "Vector and Matrix Differentiation." In Mathematics for Econometrics. Springer New York, 2000. http://dx.doi.org/10.1007/978-1-4757-3238-2_5.

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Trendafilov, Nickolay, and Michele Gallo. "Matrix analysis and differentiation." In Multivariate Data Analysis on Matrix Manifolds. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76974-1_2.

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Dhrymes, Phoebus J. "Vector and Matrix Differentiation." In Mathematics for Econometrics. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8145-4_5.

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Engel, Andreas. "Mehrdimensionale Differentiation". У Taylorentwicklung, Jacobi-Matrix, ∇, δ(x) und Co. Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/978-3-662-59752-1_7.

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Karpfinger, Christian. "Partial Differentiation: Gradient, Hessian Matrix, Jacobian Matrix." In Calculus and Linear Algebra in Recipes. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65458-3_47.

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Conference papers on the topic "Operational matrix of differentiation"

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Eddine, Khiloun Imad, Belmabrouk Karima, and Dekhici Latifa. "Matrix-Probabilistic Particle Swarm Optimization for Supply Chain Optimization." In 2024 International Conference of the African Federation of Operational Research Societies (AFROS). IEEE, 2024. https://doi.org/10.1109/afros62115.2024.11036965.

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Madhulika, Ankit Kumar, Ankit Kumar, and Lucky Singh. "A Comprehensive Derivative Operational Matrix Scheme with Modified Lucas Wavelets for Transcendental Differential Equations." In 2024 13th International Conference on System Modeling & Advancement in Research Trends (SMART). IEEE, 2024. https://doi.org/10.1109/smart63812.2024.10882472.

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MacLellan, Benjamin, Piotr Roztocki, Julie Belleville, et al. "Inverse Design of Photonic Systems." In Novel Optical Materials and Applications. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/noma.2024.now2d.4.

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We present a framework for identifying the optimal topologies and operational parameters of photonic systems. Leveraging automatic differentiation and topology search, it facilitates the discovery of physically-feasible designs for applications like waveform generation and sensing.
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Syam, Sondos M., Z. Siri, and R. Md Kasmani. "Operational Matrix Method for Solving Fractional System of Riccati Equations." In 2023 International Conference on Fractional Differentiation and Its Applications (ICFDA). IEEE, 2023. http://dx.doi.org/10.1109/icfda58234.2023.10153350.

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Hashim, I., Muhammed I. Syam, and Mwaffag Sharadga. "An Analytical Solution of Fractional Diffusion Equations using the operational matrix method." In 2023 International Conference on Fractional Differentiation and Its Applications (ICFDA). IEEE, 2023. http://dx.doi.org/10.1109/icfda58234.2023.10153266.

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Jafari, Hossein, Haleh Tajadodi, and Dumitru Baleanu. "On a numerical solution for fractional differential equation within B-spline operational matrix." In 2014 International Conference on Fractional Differentiation and its Applications (ICFDA). IEEE, 2014. http://dx.doi.org/10.1109/icfda.2014.6967392.

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Minaker, Bruce, and Francisco González. "Automatic Differentiation in Automatic Generation of the Linearized Equations of Motion." In ASME 2021 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/detc2021-69118.

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Abstract In the ongoing search for mathematically efficient methods of predicting the motion of vehicle and other multibody systems, and presenting the associated results, one of the avenues of continued interest is the linearization of the equations of motion. While linearization can potentially result in reduced fidelity in the model, the benefits in computational speed often make it the pragmatic choice. Linearization techniques are also useful in modal and stability analysis, model order reduction, and state and input estimation. This paper explores the application of automatic differentiation to the generation of the linearized equations of motion. Automatic differentiation allows one to numerically evaluate the derivative of any function, with no prior knowledge of the differential relationship to other functions. It exploits the fact that every computer program must evaluate every function using only elementary arithmetic operations. Using automatic differentiation, derivatives of arbitrary order can be computed, accurately to working precision, with minimal additional computational cost over the evaluation of the base function. There are several freely available software libraries that implement automatic differentiation in modern computing languages. In the paper, several example multibody systems are analyzed, and the computation times of the stiffness matrix are compared using direct evaluation and automatic differentiation. The results show that automatic differentiation can be surprisingly competitive in terms of computational efficiency.
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Lin, Tsung-Chieh, and K. Harold Yae. "Recursive Linearization of Multibody Dynamics and Application to Control Design." In ASME 1990 Design Technical Conferences. American Society of Mechanical Engineers, 1990. http://dx.doi.org/10.1115/detc1990-0087.

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Abstract The non-linear equations of motion in multi-body dynamics pose a difficult problem in linear control design. It is therefore desirable to have linearization capability in conjunction with a general-purpose multibody dynamics modeling technique. A new computational method for linearization is obtained by applying a series of first-order analytical approximations to the recursive kinematic relationships. The method has proved to be computationally more efficient. It has also turned out to be more accurate because the analytical perturbation requires matrix and vector operations by circumventing numerical differentiation and other associated numerical operations that may accumulate computational error.
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De Souza, E. A., L. Carraresi, G. D. Boyd, and D. A. B. Miller. "Analog Differential Self-linearized Quantum Well Self-Electrooptic Effect Modulator." In Quantum Optoelectronics. Optica Publishing Group, 1993. http://dx.doi.org/10.1364/qo.1993.qthb.1.

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We demonstrate a new mode of operation for quantum well self-electrooptic-effect devices (SEEDs) using their analog features, and our results shows that this device is potentially useful for analog systems. This device was recently proposed as a new analog SEED circuit operating with differential pairs of light beams[1]. It uses the difference in two light beam powers to represent an analog value. Normally, processing such bipolar values is difficult with optics. This new circuit allows many different analog functions to be performed, including addition, subtraction, and differentiation of images, correlation, and optically controlled bipolar matrix-vector multiplication[2]. In general, such operations operate on and generate both positive and negative values; this circuit allows full use of such values in analog systems, and, since it was fabricated using the symmetric SEED array process[4], it is compatible with being fabricated in large two-dimensional arrays. We demonstrate the linear performance of this circuit from 50 nW to 3 mW optical powers.
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Hjorungnes, Are, David Gesbert, and Daniel P. Palomar. "Unified Theory of Complex-Valued Matrix Differentiation." In 2007 IEEE International Conference on Acoustics, Speech, and Signal Processing. IEEE, 2007. http://dx.doi.org/10.1109/icassp.2007.366543.

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Reports on the topic "Operational matrix of differentiation"

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Elder, B. L., Linda A. Hansen, and Donald L. Harville. Examining Operational Measures of Performance: Performance Measures Matrix. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada251896.

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Brossia and Sridhar. L52103 Differentiation of Corrosion Mechanism by Morphological Feature Characterization - Experimental. Pipeline Research Council International, Inc. (PRCI), 2004. http://dx.doi.org/10.55274/r0010952.

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Natural gas pipeline systems often contain liquid water and other corrosive agents such as salts, CO2, H2S, O2, and bacteria. The ability to differentiate between corrosion mechanisms is crucial, if corrosion control and mitigation schemes are to be effective. The present project was undertaken to determine whether pipeline steels develop characteristic morphological features that are diagnostic to distinguish between abiotic and biotic pitting corrosion. The present report describes the experimental approach taken to conduct the tests. A separate report (by Exponent Failure Analysis Associates, Menlo Park, CA) will describe the findings and implications of the research. The work conducted has led to the development of a unique test system that enables introduction of bacterial consortia under conditions simulating operational pipelines. The test system also promotes the growth of sessile over planktonic bacteria. A significant difficulty encountered in conducting the tests is ensuring truly abiotic conditions. Several different steps and procedures were attempted to sterilze the testing system, however, due to its complexity this still proved highly difficult. It is suggested that future abiotic tests either be conducted in a completely separate system or biocides introduced to kill any opportunistic bacteria that may be present or introduced into the system.
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Osathanon, Thanaphum. Gene expression profile of continuous and intermittent compressive stress treated human periodontal ligament cells. Faculty of Dentistry Chulalongkorn University, 2019. https://doi.org/10.58837/chula.res.2019.7.

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Mechanical force regulates periodontal ligament cell (PDL) behavior. However, different force types lead to distinct PDL responses. Here, we report that pretreatment with an intermittent compressive force (ICF), but not a continuous compressive force (CCF), promoted human PDL (hPDL) osteogenic differentiation as determined by osteogenic marker gene expression and mineral deposition in vitro. ICF-induced osterix (OSX) expression was inhibited by cycloheximide and monensin. Although CCF and ICF significantly increased extracellular adenosine triphosphate (ATP) levels, pretreatment with exogenous ATP did not affect hPDL osteogenic differentiation. Gene expression profiling of hPDLs subjected to CCF or ICF revealed that extracellular matrix (ECM)-receptor interaction, focal adhesion, and transforming growth factor beta (TGF- β) signaling pathway genes were commonly upregulated, while calcium signaling pathway genes were downregulated in both CCF- and ICF-treated hPDLs. The TGFB1 mRNA level was significantly increased, while those of TGFB2 and TGFB3 were decreased by ICF treatment. In contrast, CCF did not modify TGFB1 expression. Inhibiting TGF- β receptor type I or adding a TGF- β1 neutralizing antibody attenuated the ICF-induced OSX expression. Exogenous TGF- β1 pretreatment promoted hPDL osteogenic marker gene expression and mineral deposition. Additionally, pretreatment with ICF in the presence of TGF- β receptor type I inhibitor attenuated the ICF-induced mineralization. In conclusion, this study reveals the effects of ICF on osteogenic differentiation in hPDLs and implicates TGF- β signaling as one of its regulatory mechanism.
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Arnett, Clint, and Rebekah Wilson. Evaluation of a visible light responsive photocatalytic coating to resist microbial contamination and increase indoor air quality. Engineer Research and Development Center (U.S.), 2023. http://dx.doi.org/10.21079/11681/47644.

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To meet new Department of Defense (DoD) energy standards, buildings are being constructed, and existing buildings are being retrofitted with tighter envelops. These new standards can reduce operational costs significantly but also limit fresh outdoor air coming into the built environments. This can result in the accumulation of harmful substances within buildings, which can have adverse effects on its occupants. New photocatalytic coatings may be a solution to this ever-increasing problem as they have the ability to destroy both chemical and biological toxins when activated with light. This work evaluated a novel indoor-light-reactive photocatalytic coating for its ability to eliminate or reduce microbial contamination un-der in situ test conditions. However, air and surface sampling revealed no reduction in either viable fungi and bacteria or total airborne mold spores. Additionally, no significant differentiation could be made in the composition of volatile organics between the treated and untreated areas. How-ever, testing the photocatalytic activity of the coating with standardized test methods and increased illumination, revealed the coating did exhibit antimicrobial activity against mold, bacteria, and viruses. This suggested that there may be limited benefit to using the indoor-light-reactive photocatalytic coating to inhibit microbial contamination unless specific lighting conditions can be met.
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Soldano, Miguel, Michelle Fryer, Euric Allan Bobb, et al. Evaluation of the Results of the Realignment. Inter-American Development Bank, 2014. http://dx.doi.org/10.18235/0010579.

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The Realignment defined four key goals to respond to a perceived loss of Bank relevance and presence in LAC: sharpening sector focus and expertise, sharpening country focus, strengthening risk- and results-based management, and enhancing institutional efficiency. To achieve these goals, it proposed adjustments to the Bank's structure, processes, and human resources and incentives which included, among other things, the introduction of a new matrix organization, the delegation of additional responsibilities to country offices and project team leaders, the updating of operational and corporate processes, and changes in staffing and HR policies. This evaluation concludes that the Realignment's underlying direction toward a matrix structure and greater decentralization were appropriate, but it has not yet achieved all of its objectives. There are several noteworthy trends on the positive side. The technical skills of Bank staff have improved, the capacity to generate and disseminate knowledge has increased, and more authority has been delegated to country representatives and team leaders, bringing IDB closer to the client. The collaboration between staff in the same sector in country offices and headquarters has increased, as has the continuity of project team membership over the project cycle. However, the matrix is not yet functioning well. VPC has limited authority and few mechanisms to coordinate Bank inputs at the country level to ensure delivery of a coherent and efficient program. VPS and VPP have limited opportunity or incentive to bring their knowledge and influence to bear in country strategy and programming. Sector silos are tall and the pressures to lend and disburse greater than ever. As a result, the Bank and its borrowing countries are not reaping the full potential gains from cross-matrix coordination and collaboration in country strategy and program formulation, project design and implementation, and knowledge sharing. Moreover, the evaluation did not find conclusive evidence of improved efficiency. Some processes (such as quality control at the project level) appear unnecessarily time-consuming and uncertain, and the lack of full cost accounting or binding budget constraints for task teams weakens incentives for the efficient use of resources. The report offers five broad recommendations: (i) to enhance country focus, further strengthen the country program management function in country offices; (ii) to enhance inter-VP coordination and country program coherence, strengthen the role of VPS and VPP in country strategy-setting and programming; (iii) To enhance development effectiveness, strengthen mechanisms for quality control of Bank operational products; (iv) to enhance efficiency, continue to strengthen budget processes and information systems to ensure full and accurate cost accounting; and, (v) to promote effectiveness and efficiency, fill a significantly higher share of management positions through transparent competitive processes. Under each recommendation the evaluation proposes specific measures Bank management should consider (among other options) to move in the directions recommended.
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Perk, Shimon, Maricarmen Garcia, Alexander Panshin, et al. Avian Influenza Virus H9N2: Characterization and Control Strategies. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7709882.bard.

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Control of Avian Influenza (AI) infection is a highly topical subject of major economicimportance for the worldwide poultry industry at the national level and for international trade.H9N2 viruses are endemic in poultry throughout Asia and the Middle East, causing major losses inproduction. Moreover, these viruses pose wider threats since they have been isolated from bothswine and humans. At the same time, study of the AI viruses affords an opportunity to explore anumber of problems of intriguing scientific interest. The overall goal of this project was to developa sound control strategy for avian influenza subtype H9N2 viruses (AI H9N2) in commercialpoultry in Israel. The one-year feasibility study focused on two main goals, namely: to study themolecular characteristics of AI H9N2 circulating during the last seven years in Israel and todevelop tools enabling differentiation between the immune response to vaccination and infectionwith H9N2.Genetic and phylogenetic characterization of 29 selected AI H9N2 isolates (2000-2006)was performed by complete sequencing of hemagglutinin (HA), neuraminidase (NA), and all sixinternal genes [nucleoprotein (NP), polymerase basic 1 (PB1), polymerase basic 2 (PB2),polymerase acid (PA), matrix (M), and nonstructural (NS) genes]; comparative phylogenetic andgenetic analyses of these sequences; and comparative genetic analyses of deduced amino acidsequences of the HA, NA, NS1, and NS2 proteins. The major conclusions of the molecularanalyses were: (1) Israeli isolates, together with other H9N2 viruses isolated in Middle Eastcountries, comprise a single regional sublineage related to the G1-lineage. In addition, Israeliisolates subdivided into three different subgroups. Genetic analysis of these viruses suggests thatthey underwent divergent evolution paths.
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Azuara Herrera, Oliver. IDB-9 Survey: Overview of the Results. Inter-American Development Bank, 2013. http://dx.doi.org/10.18235/0010528.

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This document describes the results of the Ninth General Capital Increase Survey (IDB-9 Survey). This was an electronic survey sent by the Office of Evaluation and Oversight (OVE) to all operational staff of the Bank between September 20 and October 4, 2012. The goal of the survey was to measure the extent of implementation of the reforms mandated in the IDB-9 Agreement. All survey responses were anonymous, and the results were aggregated at the unit level. The IDB-9 survey included up to 31 closed questions organized in the following eight modules: sector strategies (4 to 6 questions); Bank programming (4 questions), lending instruments and knowledge products (2 questions); private sector development and coordination (4 questions); Development Effectiveness Matrix (4 questions); Progress Monitoring Report (4 questions); the Independent Consultation and Investigation Mechanism (3 questions); the new Access to Information Policy (4 questions), and an open-ended question. Each staff member reported their unit and department affiliation and was asked the corresponding set of questions.
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Rodrigo, Maria Fernanda, Claudia Figueroa, Oliver Peña-Habib, Xiomara Rojas-Asqui, and Melanie Putic. OVE's Review of Project Completion Reports (PCRs) and Expanded Supervision Reports (XSRs): The 2020 Validation Cycle. Inter-American Development Bank, 2020. http://dx.doi.org/10.18235/0002944.

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This report summarizes the results of the Office of Evaluation and Oversight's (OVE) annual validation of the self-assessments of project performance and results completed by the Inter-American Development Bank (IDB) and IDB Invest in 2019-2020. The IDB and IDB Invest have systems in place to measure the development effectiveness of their operations. These systems use a number of instruments to assess projects at the design, implementation, and completion phases. The design-phase assessment uses a “Development Effectiveness Matrix” (DEM) for sovereign guaranteed (SG) operations. The effectiveness of non-sovereign guaranteed (NSG) operations is measured with a “Development Effectiveness Learning, Tracking, and Assessment tool” (DELTA). Implementation-phase assessments measure SG operations with “Project Monitoring Reports,” while NSG operations are assessed with “Project Supervision Reports.” Upon completion, SG projects are self-evaluated with “Project Completion Reports,” or PCRs. NSG operations, use “Expanded Supervision Reports,” or XSRs when they reach early operation maturity (EOM). OVE validates Managements self-evaluations (PCRs and XSRs) and assigns a final project performance rating to each operation. As part of the 2020 validation cycle, OVE reviewed PCRs for 63 operations, 62 with operational closure (CO fully justified) in 2018 and one in 2013. XSRs were reviewed for 36 IDB Invest operations that had reached early operating maturity (EOM) in 2018.
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Littles, Chanda, David Trachtenbarg, Hans Moritz, et al. Site selection and conceptual designs for beneficial use of dredged material sites for habitat creation in the lower Columbia River. Engineer Research and Development Center (U.S.), 2024. http://dx.doi.org/10.21079/11681/48550.

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Channel maintenance in most major rivers throughout the United States requires ongoing dredging to maintain navigability. The US Army Corps of Engineers explores several options for placement based on sediment characteristics, material quantity, cost, operational constraints, and minimization of potential adverse effects to existing resources and habitat. It is a priority to beneficially reuse dredged sediments to create habitat and retain sediments within the river system whenever possible. Nonetheless, there can be discrepancies among state and federal resource agencies, landowners, tribes, and various other stakeholders about what constitutes a benefit and how those benefits are ultimately weighed against short- and long-term tradeoffs. This work leveraged prior Regional Sediment Management efforts building consensus among stakeholders on a suite of viable strategies for in-water placement in the lower Columbia River. The goal was to identify suitable locations for applying the various strategies to maximize habitat benefits and minimize potential adverse effects. A multistep site-selection matrix was developed with criteria accounting for existing site conditions, overall placement capacity, tradeoffs, long-term maintenance, cost, stakeholder concerns, and landscape principles in the context of other habitat restoration projects implemented in the lower river. Three highly ranked sites were selected for conceptual design and exemplify results of collaborative beneficial use implementation.
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Mohammadian, Abolfazl, Mohammad Miralinaghi, Alireza Talebpour, Sajad Askari, and Sanaz Kazemzadehazad. State Department of Transportation Support for Operationalizing Transit Signal Priority. Illinois Center for Transportation, 2025. https://doi.org/10.36501/0197-9191/25-005.

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Transit signal priority (TSP) systems have become an integral part of regional intelligent transportation systems integration. They modify signal operations to facilitate faster transit through intersections, improve transit service reliability, reduce delays, and enhance overall transit operational efficiency. Agencies are planning and implementing next-generation TSP systems. However, multifaceted challenges complicate TSP implementation, particularly in urban regions with high traffic density and multiple stakeholders. Exploring these challenges can help develop more efficient deployment strategies and improve system performance. This study’s researchers, therefore, examined TSP implementation challenges in the metropolitan Chicago area and interviewed stakeholders and experts from Illinois and other states to identify successes and obstacles in TSP deployment. They applied a thematic analysis and a non-negative matrix factorization method to identify key barriers. To prioritize these challenges, they developed a survey using the fuzzy analytic hierarchy process framework and had experts directly involved in TSP operations in the Chicago region participate in this survey. Study findings indicated that organizational factors—such as interagency coordination issues and labor shortages—are significant challenges. Regulatory and policy constraints, including the absence of standardized regional guidelines and concerns over equipment compatibility, further hinder TSP deployment. Financial constraints, particularly the reliance on fragmented funding sources, create uncertainty in project execution. Technological limitations, such as integration difficulties with legacy traffic control systems and the high costs of infrastructure upgrades, also impede implementation.
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