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Journal articles on the topic 'Ophthalmic system'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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1

Stanković - Babić, Gordana, Rade R. Babić, and Zoran Milošević. "THE OPHTHALMIC INFORMATION SYSTEM." Acta Medica Medianae 57, no. 1 (March 15, 2018): 116–21. http://dx.doi.org/10.5633/amm.2018.0117.

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2

Eguchi, Shuichiro. "Stereoscopic Ophthalmic Microendoscope System." Archives of Ophthalmology 115, no. 10 (October 1, 1997): 1336. http://dx.doi.org/10.1001/archopht.1997.01100160506028.

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3

Anjali, Sharma, Dass Rameshwar, Dhiman Shivani, and Singh Ranjit. "Hydrogels in ophthalmic drug delivery system - A mini review." Asian Pacific Journal of Health Sciences 5, no. 2 (June 2018): 96–104. http://dx.doi.org/10.21276/apjhs.2018.5.2.19.

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4

Alani, Safwat David. "The ophthalmic rod: A new ophthalmic drug delivery system I." Graefe's Archive for Clinical and Experimental Ophthalmology 228, no. 4 (1990): 297–301. http://dx.doi.org/10.1007/bf00920050.

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5

Sahu, Ekta Singh, Pavan Humesh Shroff, Animesh Sahu, Arun Bhargava, and Balkishan Sharma. "Ophthalmic manifestations of proboscis lateralis." BMJ Open Ophthalmology 6, no. 1 (July 2021): e000558. http://dx.doi.org/10.1136/bmjophth-2020-000558.

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Proboscis lateralis (PL) is a rare congenital malformation of the craniofacial structure with varied clinical associations. None of the studies documented a discrete review of ophthalmic presentations in PL. The principal aim of the present study is to explore the ophthalmic manifestations of PL. The ancillary goal is to derive a relationship between congenital deformity in PL and various ophthalmic anomalies. Databases were searched in order to obtain articles related to PL. A qualitative systematic analysis of 100 subjects was performed. In PL, eyelid coloboma (32.6%) is the most common ocular feature, followed by hypertelorism (25.3%), iris coloboma (22.4%), lacrimal system abnormality (20.7%), malpositioned eyebrow (14.4%) and retinochoroidal coloboma (12.9%). Sinonasal deformity is the most common systemic abnormality, detected in 87.9% of cases of PL, as compared with central nervous system involvement (56.2%) and other anomalies. The analysis showed a strong significant association between brain abnormalities and hypertelorism (p=0.000) and between brain abnormalities and micro-ophthalmia/anophthalmia (p=0.000). Statistically significant association was noted between cumulative ocular abnormalities and cumulative systemic abnormalities (p=0.001). The present study on PL reviewed the salient features of this rare congenital disorder. The study outcome provides a new aspect to concomitant ocular abnormalities. This study supports the view that other congenital anomalies in cases of PL had significant influence on certain ophthalmic anomalies.

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6

Fortune, Brad. "Neuro-Ophthalmic System: Clinical Procedures." Optometry and Vision Science 76, no. 11 (November 1999): 738. http://dx.doi.org/10.1097/00006324-199911000-00020.

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7

Fisher, Yale L. "A Disposable Ophthalmic Endoscopic System." Archives of Ophthalmology 112, no. 7 (July 1, 1994): 984. http://dx.doi.org/10.1001/archopht.1994.01090190132034.

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8

Dufynets, V. A., and T. S. Hruzeva. "Optimized modern regional system of provision of ophthalmic care to the population in the conditions of multiform health system." One Health and Nutrition Problems of Ukraine 50, no. 1 (May 7, 2019): 40–49. http://dx.doi.org/10.33273/2663-9726-2019-50-1-40-49.

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Introduction. In today's conditions of the epidemic of non-infectious diseases, the significant increase in the incidence of diseases of the eye and its adnexa, disability due to eye diseases, including blindness, providing the population with affordable and quality medical care is a priority of any country. This requires the introduction of modern organizational models for providing ophthalmic care in terms of multiform health system. The Aim of the Study. the rationale for a modern regional system of provision of ophthalmic care to the population in conditions of multiform health system. Material and Methods. In the course of the study bibliographic, epidemiological, medical-statistical, sociological methods were used. Results. The study identified shortcomings in the organization and provision of ophthalmic services to the population of the region, lack of resources to ensure the real needs of the population in ophthalmic care, low level of cooperation between communal and private health care institutions. A high need for ophthalmic services was identified in view of the increase in incidence (by 41.7 %) and prevalence (47.1 %) of eye diseases among the population of the region during 2000–2015 and overload in the work of the ophthalmic service, as evidenced by the significant occupancy of profile beds throughout the year (360.7 days), short treatment terms (6.8 days) and high rates of bed turnover (53.1), with lower than the average in the country of provision population by specialists of the ophthalmologic profile (by 19.6 %). This, along with other factors, negatively affected the availability and quality of medical services, which is confirmed by the results of a sociological survey. In contrast, from 69.7 to 92.2 per 100 respondents highly estimated the quality of service in private institutions, with their full availability for 54.3 per 100 respondents. Based on the results of the research and taking into account the strategic directions of the development of the domestic health care system, recommendations of international organizations, the author justified the modern regional system of providing ophthalmic care to the population in the conditions of multiform health care and its administrative, normative-legal, information-analytical, educational-methodological, research, communicative functions. Conclusions. The modern regional system of provision of ophthalmic care to the population in the conditions of multiform health system will increase the accessibility and quality of ophthalmic services to the population of the region, optimize the formation and distribution of resources for health care, create a competitive environment, increase the level of cooperation between health care institutions of various forms of ownership with positions of the patient-oriented approach, to introduce modern medical-organizational and medical-preventive technologies into the work of medical institutions.

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9

Rohlf, Jeffrey, and Mark A. Bullimore. "System For Ophthalmic Dispensing, Third Edition." Optometry and Vision Science 84, no. 11 (November 2007): 1006. http://dx.doi.org/10.1097/opx.0b013e31815a01dd.

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10

Fowler, Colin. "System for Ophthalmic Dispensing, 2nd ed." Optometry and Vision Science 74, no. 11 (November 1997): 878. http://dx.doi.org/10.1097/00006324-199711000-00018.

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11

Gurram, Murali Mohan. "Ophthalmic cell-phone imaging system: a costless imaging system." Canadian Journal of Ophthalmology 48, no. 5 (October 2013): e135-e139. http://dx.doi.org/10.1016/j.jcjo.2013.06.007.

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12

Shastri, DH, PK Shelat, AK Shukla, and PB Patel. "Ophthalmic drug delivery system: Challenges and approaches." Systematic Reviews in Pharmacy 1, no. 2 (2010): 113. http://dx.doi.org/10.4103/0975-8453.75042.

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13

Mujat, Mircea, R. Daniel Ferguson, Ankit H. Patel, Nicusor Iftimia, Niyom Lue, and Daniel X. Hammer. "High resolution multimodal clinical ophthalmic imaging system." Optics Express 18, no. 11 (May 18, 2010): 11607. http://dx.doi.org/10.1364/oe.18.011607.

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14

Miller, Joseph M. "The Computer-Based Ophthalmic Recordkeeping (COR) System." Journal of Pediatric Ophthalmology & Strabismus 33, no. 1 (January 1996): 55–58. http://dx.doi.org/10.3928/0191-3913-19960101-14.

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15

Papakostopoulos, D., M. Everingham, Y. Gogolitsyn, K. Dodson, S. Papakostopoulos, and J. C. Dean-Hart. "Comprehensive standardized ophthalmic telemedicine." Journal of Telemedicine and Telecare 3, no. 1_suppl (June 1997): 49–52. http://dx.doi.org/10.1258/1357633971930355.

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The Electrodiagnostic Neurophysiological Automated Analysis (ENAA) telematic system was developed in the EU EUREKA project. To validate the system 2500 electrodiagnostic tests were administered in a standardized manner during a three-year period. The tests were performed on 70 normal subjects and 500 patients in five laboratories in three European countries. The data were transmitted to the Bristol Telematic Electrodiagnostic Centre in the Bristol Eye Hospital. Data from normal subjects were not significantly different between laboratories. Data from patients were reported upon and the conclusions transmitted to the place of origin. The system provided the remote consultant with multimedia data, including medical images such as colour fundus photography and angiography, video and sound.

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16

Al Dousary, Surayie H., and Fatma H. Al Anazy. "Ophthalmic Manifestations of PNS Disease: A Grading System." Otolaryngology–Head and Neck Surgery 145, no. 2_suppl (August 2011): P125—P126. http://dx.doi.org/10.1177/0194599811416318a270.

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17

Jiang, Peng-Fei, Jun Peng, Ya-Sha Zhou, Yi-Chen Li, Qing-Hua Peng, and Xiang-Dong Chen. "Ophthalmic Syndrome Differentiation System and Digital Chinese Medicine." Digital Chinese Medicine 1, no. 1 (March 2018): 9–13. http://dx.doi.org/10.1016/s2589-3777(19)30003-5.

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18

Doijad, RC, FV Manvi, V. S. N. Malleswara Rao, and Prajakta Alase. "Sustained ophthalmic delivery of gatifloxacin fromIn situgelling system." Indian Journal of Pharmaceutical Sciences 68, no. 6 (2006): 814. http://dx.doi.org/10.4103/0250-474x.31025.

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19

张, 闯. "Research Progress of Nanoparticle Ophthalmic Drug Delivery System." Pharmacy Information 08, no. 03 (2019): 73–78. http://dx.doi.org/10.12677/pi.2019.83009.

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20

Vasantha, V., P. K. Sehgal, and K. Panduranga Rao. "Collagen ophthalmic inserts for pilocarpine drug delivery system." International Journal of Pharmaceutics 47, no. 1-3 (November 1988): 95–102. http://dx.doi.org/10.1016/0378-5173(88)90219-0.

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21

Song, Jing-Yao, Xue-Guang Wang, Zi-Yuan Zhang, Lin Che, Bin Fan, and Guang-Yu Li. "Endoplasmic reticulum stress and the protein degradation system in ophthalmic diseases." PeerJ 8 (February 20, 2020): e8638. http://dx.doi.org/10.7717/peerj.8638.

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Objective Endoplasmic reticulum (ER) stress is involved in the pathogenesis of various ophthalmic diseases, and ER stress-mediated degradation systems play an important role in maintaining ER homeostasis during ER stress. The purpose of this review is to explore the potential relationship between them and to find their equilibrium sites. Design This review illustrates the important role of reasonable regulation of the protein degradation system in ER stress-mediated ophthalmic diseases. There were 128 articles chosen for review in this study, and the keywords used for article research are ER stress, autophagy, UPS, ophthalmic disease, and ocular. Data sources The data are from Web of Science, PubMed, with no language restrictions from inception until 2019 Jul. Results The ubiquitin proteasome system (UPS) and autophagy are important degradation systems in ER stress. They can restore ER homeostasis, but if ER stress cannot be relieved in time, cell death may occur. However, they are not independent of each other, and the relationship between them is complementary. Therefore, we propose that ER stability can be achieved by adjusting the balance between them. Conclusion The degradation system of ER stress, UPS and autophagy are interrelated. Because an imbalance between the UPS and autophagy can cause cell death, regulating that balance may suppress ER stress and protect cells against pathological stress damage.

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22

Huang, Jing, Yong Cui, Chunting Sun, and Xinyan Liu. "Development of Moxifloxacin Hydrochloride Thermoreversible Ocular Delivery System for the Treatment of Conjunctivitis." Journal of Biomaterials and Tissue Engineering 10, no. 7 (July 1, 2020): 1010–14. http://dx.doi.org/10.1166/jbt.2020.2365.

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The present investigation deals with formulation and development of novel ophthalmic in situ gel formulation of Moxifloxacin in order to treat common disorder of conjunctivitis. The formulation contains combination of two polymers like Poloxamer 4–7 and chitosan both help in sustaining and increasing the drug release as well as retention time of drug at contact site. Thus developed formulation was evaluated for various parameters. The moxifloxacin in situ gel was found to be clear with ph in range of 6.8–7.0. The gelling time was also found to be quick with prolong retention up to 8 hrs. The optimized batch showed maximum release of 99.98% and was found to have sustained action when compared to marketed ophthalmic eye drop formulation. The formulation of Ophthalmic Thermosensitive in situ gel for Moxifloxacin was successfully prepared using Polymer combination of Poloxamer 407 and chitosan and found effective in the treatment of Conjunctivitis.

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23

George, Eby, and Chinju M. Sivaraman. "FORMULATION AND EVALUATION OF IN-SITU GEL FORMING OPHTHALMIC DRUG DELIVERY SYSTEM CONTAINING ATROPINE SULPHATE." INDIAN RESEARCH JOURNAL OF PHARMACY AND SCIENCE 7, no. 2 (June 2020): 2324–36. http://dx.doi.org/10.21276/irjps.2020.7.2.23.

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24

Todoran, Nicoleta, Adriana Ciurba, Emőke Rédai, V. Ion, Luminița Lazăr, and Emese Sipos. "Limitations when use chloramphenicol-bcyclodextrins complexes in ophtalmic solutions buffered with boric acid/borax system." Acta Medica Marisiensis 60, no. 6 (December 1, 2014): 269–74. http://dx.doi.org/10.1515/amma-2015-0007.

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Abstract Chloramphenicol eye drops are commonly prescribed in concentrations of 0.5-1% in the treatment of infectious conjunctivitis. In terms of ophthalmic solution preparation, the major disadvantage of chloramphenicol consists in its low solubility in water. The solubility is increased by substances that form chloramphenicol-complexes, for example: boric acid/borax or cyclodextrins. Objective: Experimental studies aimed to evaluate the potential advantages of enhancing the solubility and stability of chloramphenicol (API) by molecular encapsulation in b-cyclodextrin (CD), in formulation of ophthalmic solutions buffered with boric acid/borax system. Methods and Results: We prepared four APIb- CD complexes, using two methods (kneading and co-precipitation) and two molar ratio of API/b-cyclodextrin (1:1 and 1:2). The formation of complexes was proved by differential scanning calorimetry (DSC) and the in vitro dissolution tests. Using these compounds, we prepared eight ophthalmic solutions, formulated in two variants of chloramphenicol concentrations (0.4% and 0.5%). Each solution was analyzed, by the official methods, at preparation and periodically during three months of storing in different temperature conditions (4°C, 20°C and 30°C). Conclusions: Inclusion of chloramphenicol in b-cyclodextrin only partially solves the difficulties due to the low solubility of chloramphenicol. The protection of chloramphenicol molecules is not completely ensured when the ophthalmic solutions are buffered with the boric acid/borax system.

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Bocic, Ronny, Cristobal Vallejos, Alejandro Alvarez-Lueje, and Fernando LÓpez. "Liquid Chromatographic Assay for Naphazoline and Antazoline in Ophthalmic Preparations." Journal of AOAC INTERNATIONAL 75, no. 5 (September 1, 1992): 902–4. http://dx.doi.org/10.1093/jaoac/75.5.902.

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Abstract A liquid chromatographic (LC) analysis has been developed for determining naphazoline and antazoline in ophthalmic preparations. The LC system is designed so that a variety of ophthalmic solutions containing naphazoline and antazoline can be analyzed with precision.

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26

McMaster, David, and Mahfouth Abdallah Bamashmus. "Ophthalmic services during ongoing conflict: the eye health system in Yemen." BMJ Global Health 4, no. 5 (October 2019): e001743. http://dx.doi.org/10.1136/bmjgh-2019-001743.

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There is little information on the provision of ophthalmic services and the eye health system in Yemen. Using the WHO framework for analysing health systems, we aim to assess what is known about the current eye health system in Yemen with ongoing conflict. Financial constraints, transportation difficulties and security instability are barriers for many of Yemen’s people in need of healthcare. The most recent cataract surgical rate reported in 2012 is 2473 operations per million population, with an increase in operations performed in charity eye camps and the private sector. We identify many governorates of Yemen have inadequate ophthalmic resources. We describe the need for short-term solutions to reduce the backlog prevalence of blindness while local infrastructure is rebuilt, and the importance of long-term reconstruction and transition to local ownership with a sustainable workforce and health service as peace is restored.

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27

Burgess, S., J. Foulds, P. White, B. Foot, and C. MacEwen. "A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery." Journal of Laryngology & Otology 134, no. 3 (March 2020): 228–32. http://dx.doi.org/10.1017/s0022215120000468.

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AbstractObjectivesThis prospective, epidemiological British Ophthalmological Surveillance Unit study into ophthalmic complications of functional endoscopic sinus surgery aimed to determine the minimum incidence, presenting features and management throughout the UK.MethodsCases of ophthalmic complications of functional endoscopic sinus surgery, between February 2016 and February 2018, were identified through the British Ophthalmological Surveillance Unit reporting card system. Reporting ophthalmic consultants were sent an initial questionnaire, followed by a second questionnaire at six months.ResultsTwenty-six cases of ophthalmic complications of functional endoscopic sinus surgery were reported. The majority (16 cases (62 per cent)) had limitations of ocular motility at presentation. The most common final diagnosis was rectus muscle (33 per cent) and nasolacrimal duct trauma (27 per cent). Using national data, this study reports a minimum incidence of ophthalmic complications of functional endoscopic sinus surgery in the UK of 0.2 per cent over two years.ConclusionIn terms of ophthalmic complications, functional endoscopic sinus surgery is shown to be safe. Ophthalmic complications are rare, but when they do occur, they commonly result in rectus muscle trauma, often requiring surgical intervention.

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28

Astrahan, Melvin A., Gary Luxton, Gabor Jozsef, Thomas D. Kampp, Peter E. Liggett, Michael D. Sapozink, and Zbigniew Petrovich. "An interactive treatment planning system for ophthalmic plaque radiotherapy." International Journal of Radiation Oncology*Biology*Physics 18, no. 3 (March 1990): 679–87. http://dx.doi.org/10.1016/0360-3016(90)90077-w.

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29

Kozaki, Masaru, and Hisako Tanaka. "SCREENING SYSTEM: School Physical Examination and Mass Ophthalmic Screening." Pediatrics International 27, no. 3 (September 1985): 385–91. http://dx.doi.org/10.1111/j.1442-200x.1985.tb00658.x.

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30

Eguchi, Shuichiro. "A New Ophthalmic Electronic Videoendoscope System for Intraocular Surgery." Archives of Ophthalmology 108, no. 12 (December 1, 1990): 1778. http://dx.doi.org/10.1001/archopht.1990.01070140132046.

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31

Mittal, Neeraj, and Gurpreet Kaur. "In situgelling ophthalmic drug delivery system: Formulation and evaluation." Journal of Applied Polymer Science 131, no. 2 (August 9, 2013): n/a. http://dx.doi.org/10.1002/app.39788.

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32

Sathyan, K., A. B. Wedding, H. Y. Hsu, and K. Gopinath. "Creating Micro-Orifice Using a Modified Ophthalmic Laser System." Materials and Manufacturing Processes 26, no. 9 (September 2011): 1188–95. http://dx.doi.org/10.1080/10426914.2011.577871.

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33

Singh, Vinod, SS Bushetti, Raju Appala, Adil Shareef, SyedS Imam, and Mamta Singh. "Stimuli-sensitive hydrogels: A novel ophthalmic drug delivery system." Indian Journal of Ophthalmology 58, no. 6 (2010): 477. http://dx.doi.org/10.4103/0301-4738.71677.

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34

Alani, Safwat David, and Wolfgang Hammerstein. "The ophthalmic rod ? a new drug-delivery system II." Graefe's Archive for Clinical and Experimental Ophthalmology 228, no. 4 (1990): 302–4. http://dx.doi.org/10.1007/bf00920051.

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35

Astrahan, Melvin A., Gary Luxton, Gabor Jozsef, Thomas D. Kampp, Peter E. Liggett, Michael D. Sapozink, and Zbigniew Petrovich. "An interactive treatment planning system for ophthalmic plaque radiotherapy." Medical Dosimetry 15, no. 4 (1990): 240. http://dx.doi.org/10.1016/0958-3947(90)90019-e.

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36

Odufuwa, T. O. Bola, Lola Solebo, and Sancy Low. "Diagnostic decision support in ophthalmology." Journal of Telemedicine and Telecare 13, no. 1_suppl (July 2007): 44–46. http://dx.doi.org/10.1258/135763307781645121.

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Isabel is a Web-based, diagnostic decision support tool designed to provide a differential diagnosis of a patient's condition for interpretation by a qualified health-care professional. We investigated the accuracy of the Isabel system in ophthalmic primary care. A total of 100 case histories were prospectively collected from ophthalmic primary care clinic records. The patient demographics and clinical features of each case were then entered into the Isabel system, and the results generated by the decision support tool for each case were compared with the diagnosis reached by the ophthalmic team. Of the 100 cases in the dataset, there was no matching diagnosis in the first 2 pages of Isabel results in 40 cases. Of the 60 cases in which there was a matching diagnosis on the first 2 pages of results, 31 had a >50% match between the terms of the query and the Isabel diagnosis reminder system's database. It remains to be established whether this is high enough to be clinically useful in a practice setting. Inclusion of specific ophthalmic knowledge would probably improve the accuracy of the Isabel clinical diagnostic decision support system.

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Esteban-Pérez, Sergio, Irene Bravo-Osuna, Vanessa Andrés-Guerrero, Irene T. Molina-Martínez, and Rocío Herrero-Vanrell. "Trojan Microparticles Potential for Ophthalmic Drug Delivery." Current Medicinal Chemistry 27, no. 4 (March 9, 2020): 570–82. http://dx.doi.org/10.2174/0929867326666190905150331.

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The administration of drugs to treat ocular disorders still remains a technological challenge in this XXI century. Although there is an important arsenal of active molecules useful to treat ocular diseases, ranging from classical compounds to biotechnological products, currenty, no ideal delivery system is able to profit all their therapeutic potential. Among the Intraocular Drug Delivery Systems (IODDS) proposed to overcome some of the most important limitations, microsystems and nanosystems have raised high attention. While microsystems are able to offer long-term release after intravitreal injection, nanosystems can protect the active compound from external environment (reducing their clearance) and direct it to its target tissues. In recent years, some researchers have explored the possibility of combining micro and nanosystems in “Nanoparticle-in-Microparticle (NiMs)” systems or “trojan systems”. This excellent idea is not exempt of technological problems, remains partially unsolved, especially in the case of IODDS. The objective of the present review is to show the state of art concerning the design, preparation and characterization of trojan microparticles for drug delivery and to remark their potential and limitations as IODDS, one of the most important challenges faced by pharmaceutical technology at the moment.

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Achiron, Asaf, Yotam Hamiel, Elisha Bartov, and Zvia Burgansky-Eliash. "Computerized patient record system: Free software for the ophthalmic clinic." African Journal of Medical and Health Sciences 14, no. 2 (2015): 155. http://dx.doi.org/10.4103/2384-5589.170201.

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Naveed, Safila, Sidra Farooq, Syeda Sarah Abbas, Syed Hameez Jawed, Fatima Qamar, Mirza Yasir Hussain, and Iqra Ali. "Contemporary Trends in Novel Ophthalmic Drug Delivery System: An Overview." OALib 02, no. 05 (2015): 1–10. http://dx.doi.org/10.4236/oalib.1101497.

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Perdomo-Charry, Oscar Julián, Andrés Daniel Pérez-Pérez, Melissa De-la-Pava-Rodríguez, Hernán Andrés Ríos-Calixto, Víctor Alfonso Arias-Vanegas, Juan Sebastián Lara-Ramírez, Santiago Toledo-Cortés, Jorge Eliecer Camargo-Mendoza, Francisco José Rodríguez-Alvira, and Fabio Augusto González-Osorio. "SOPHIA: System for Ophthalmic Image Acquisition, Transmission, and Intelligent Analysis." Revista Facultad de Ingeniería 29, no. 54 (September 29, 2020): e11769. http://dx.doi.org/10.19053/01211129.v29.n54.2020.11769.

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Ocular diseases are one of the main causes of irreversible disability in people in productive age. In 2020, approximately 18% of the worldwide population was estimated to suffer of diabetic retinopathy and diabetic macular edema, but, unfortunately, only half of these people were correctly diagnosed. On the other hand, in Colombia, the diabetic population (8% of the country’s total population) presents or has presented some ocular complication that has led to other associated costs and, in some cases, has caused vision limitation or blindness. Eye fundus images are the fastest and most economical source of ocular information that can provide a full clinical assessment of the retinal condition of patients. However, the number of ophthalmologists is insufficient and the clinical settings, as well as the attention of these experts, are limited to urban areas. Also, the analysis of said images by professionals requires extensive training, and even for experienced ones, it is a cumbersome and error-prone process. Deep learning methods have marked important breakthroughs in medical imaging due to outstanding performance in segmentation, detection, and disease classification tasks. This article presents SOPHIA, a deep learning-based system for ophthalmic image acquisition, transmission, intelligent analysis, and clinical decision support for the diagnosis of ocular diseases. The system is under active development in a project that brings together healthcare provider institutions, ophthalmology specialists, and computer scientists. Finally, the preliminary results in the automatic analysis of ocular images using deep learning are presented, as well as future work necessary for the implementation and validation of the system in Colombia.

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41

Sarkies, Nicholas. "Neuro-ophthalmic aspects of systemic and central nervous system disease." Current Opinion in Ophthalmology 2, no. 5 (October 1991): 524–30. http://dx.doi.org/10.1097/00055735-199110000-00002.

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42

Dutra-Medeiros, Marco, João Nascimento, José Henriques, Sandra Barrão, Ana Fernandes-Fonseca, Nuno Aguiar-Silva, Nuno Moura-Coelho, and Victor Ágoas. "Three-Dimensional Head-Mounted Display System for Ophthalmic Surgical Procedures." Retina 37, no. 7 (July 2017): 1411–14. http://dx.doi.org/10.1097/iae.0000000000001514.

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Bucolo, Claudio, Adriana Maltese, Francesco Maugeri, Barbara Busà, Giovanni Puglisi, and Rosario Pignatello. "Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene." Journal of Pharmacy and Pharmacology 56, no. 7 (July 2004): 841–46. http://dx.doi.org/10.1211/0022357023835.

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Wu, Yumei, Yuanyuan Liu, Xinyue Li, Dereje Kebebe, Bing Zhang, Jing Ren, Jun Lu, Jiawei Li, Shouying Du, and Zhidong Liu. "Research progress of in-situ gelling ophthalmic drug delivery system." Asian Journal of Pharmaceutical Sciences 14, no. 1 (January 2019): 1–15. http://dx.doi.org/10.1016/j.ajps.2018.04.008.

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KASSEM, M., A. ABDELRAHMAN, M. GHORAB, M. AHMED, and R. KHALIL. "Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs." International Journal of Pharmaceutics 340, no. 1-2 (August 1, 2007): 126–33. http://dx.doi.org/10.1016/j.ijpharm.2007.03.011.

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Durrani, A. M., N. M. Davies, M. Thomas, and I. W. Kellaway. "Pilocarpine bioavailability from a mucoadhesive liposomal ophthalmic drug delivery system." International Journal of Pharmaceutics 88, no. 1-3 (December 1992): 409–15. http://dx.doi.org/10.1016/0378-5173(92)90340-8.

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Al Anazy, Fatma H., and Surayie H. Al Dousary. "Ophthalmic manifestations of paranasal sinus disease: a clinical grading system." International Forum of Allergy & Rhinology 2, no. 4 (March 12, 2012): 331–35. http://dx.doi.org/10.1002/alr.21029.

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Bulboaca, Adriana, Corina Ursu, and A. Bulboaca. "EVALUATION OF VASOMOTOR RESPONSE IN OPHTHALMIC MIGRAINE PATIENTS." Romanian Journal of Neurology 15, no. 2 (June 30, 2016): 75–79. http://dx.doi.org/10.37897/rjn.2016.2.4.

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Introduction. Hemodynamic changes of the cerebral arteries in ophthalmic migraine may be an important pathophysiological mechanism of the disease. The nitric oxide (NO) synthesis plays a significant role in hemodynamic changes due to vasodilatation effect. The purpose of this study is to evaluate the possible hemodynamic changes by Doppler measurements and their correlation with NO synthesis in ophthalmic migraine. Method. 37 ophthalmic migraine patients were compared with 35 healthy volunteers. Other cerebral and ophthalmic diseases were excluded by ophthalmological, neurological, and cranial MRI examinations. The migraine assessment scale (MIDAS) was used for clinical evaluation. Transcranial Doppler ultrasonography (TCD) was performed using 2 and 4 MHz frequencies transducers. The flow velocities of the internal carotid artery, middle cerebral artery, posterior cerebral artery, and NO plasma concentration were assessed 2 hours after migraine attacks. Results. The NO synthesis was significantly increased compared to the control group. The flow velocities decreased in internal carotid artery, middle cerebral artery, and posterior cerebral artery. The correlation between decreased flow velocities and NO plasma concentration was significant. Conclusions. Autonomic nervous system dysfunction in ophthalmic migraine is an important pathophysiological mechanism. The flow velocity status may reflect the vasomotor response and endothelial reactivity induced by NO synthesis. Further studies on the vasomotor response are necessary for the evaluation of this pathophysiological mechanism implication in ophthalmic migraine.

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Raizada, Seemant, Jamal Al Kandari, and Khalid Al Sabti. "Ophthalmic endoscope: A novel diagnostic imaging tool." International Journal of Diagnostic Imaging 4, no. 2 (March 16, 2017): 9. http://dx.doi.org/10.5430/ijdi.v4n2p9.

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The purpose of the study was to evaluate the feasibility of ophthalmic endoscope as a diagnostic tool. This was a prospective, non-comparative, interventional clinical study of 11 consecutive patients who underwent endoscopy-assisted management for ocular pathologies. We used a fused fiber-optic type of endoscope to visualize areas of the eye which were not seen clearly, due to media opacity, through conventional viewing systems like indirect ophthalmoscopy or wide angle viewing system. Eleven cases were enrolled in the study. Five patients underwent endoscopic examination of the fundus prior to penetrating keratoplasty (PKP) or keratoprosthesis. In one out of these 5 cases, PKP was differed due to pale optic nerve. Patient number 6, 7 & 8 were cases of recurrent vitreous hemorrhage. In these patients, endoscope was used to inspect the sclerotomy from inside and to remove incarcerated vitreous and fibro-vascular membrane. Patient number 9 was a case of poorly dilating pupil undergoing cataract surgery. Endoscope was used in this patient to locate the exact position of haptics of PCIOL. In cases 10 and 11, endoscope was used to localize ciliary sulcus and to document the position of haptics of sclera fixated IOL. Conclusion: The ophthalmic endoscope provides valuable information by illuminating, video recording, and by providing clear view of areas not visible by conventional viewing systems. It can help in management strategies in selected cases.

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AlHarkan, Dora Hamad, Rawan Mohammed A. Altowayan, Amjad Mohammed Alharbi, Sahar Mohammed Aljumaiah, Lamia Ibrahim Alhijji, and Buthaina Suliaman B. Alkhezzy. "Pattern of ophthalmic referral from primary healthcare centres to secondary and tertiary hospitals in Qassim Province, Saudi Arabia." International Surgery Journal 7, no. 6 (May 26, 2020): 1763. http://dx.doi.org/10.18203/2349-2902.isj20202379.

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Background: References of patients with ocular diseases are an indirect indicator that reflects integration of primary eye care into primary health care system. The study reviewed the ophthalmic references from four randomly selected primary health care centres to ophthalmic unit of secondary and tertiary hospitals in Qassim Province of Saudi Arabia.Methods: This was a retrospective health record review study was undertaken at four PHC centres in Qassim region during the year 2017. All cases referred for eye care from January 2015 until December 2016 were included. Prevalence of ophthalmic reference, profile of ophthalmic patients and ophthalmic diagnosis were analysed.Results: From primary health care centres, 423 eye cases from 1,387,996 population of catchment area were referred. The annual prevalence of eye reference was 1.5 per 10,000. Vision screening and diabetic retinopathy evaluation comprised of 55.5% of total reference.Conclusions: Poor reference pattern from primary health care centers to secondary and tertiary eye centre suggest urgent and strong need of implementing primary eye care in the primary health care centres of Saudi Arabia. Referral of simple eye cases are increasing the workload of ophthalmologists and can delay urgent referrals like cases of diabetic retinopathy screening.

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