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Journal articles on the topic 'Opioid prescription and Workplace productivity'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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1

Praveen, Kumar Mishra* Swati Khare Dr. Jitendra Banweer. "Impact of Opioid Toxicity on Workplace Productivity." International Journal of Scientific Research and Technology 2, no. 5 (2025): 401–7. https://doi.org/10.5281/zenodo.15426428.

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Opioids are derived from opiates they include also synthetic and semi-synthetic drugs. Opioids have both recreational and medical uses. Opioid abuse is a worldwide problem with numerous and increasing mortality due to overdose. Opioids act on the opiate receptors as a potent mu receptor agonist resulting in a complex intracellular signals leading to dopamine release causing euphoria, and pain signal blocking. In cases of overdose, there is an excessive effect on respiratory center, resulting in respiratory depression and eventually death. Opioids can lower the perception of pain and in some ca
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2

Beswick, Adam, and Caroline Piccininni. "The cost of pain." University of Western Ontario Medical Journal 87, no. 1 (2018): 71–72. http://dx.doi.org/10.5206/uwomj.v87i1.1925.

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Prescription opioid use has historically been a regular component of the management of chronic nonmalignant pain in Canada. However, the economic implications of high rates of addiction and abuse have motivated consideration of more cost-effective management strategies for chronic pain. The economic burden imposed by prescription opioid use relates in part to lost workplace productivity, increased addiction treatment program costs, and increased overall healthcare expenditure for these patients. In this article, we present research on the economic implications of the current rates of opioid pr
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Fuhrmann-Berger, Jennifer. "The economic impact of opioid addiction." Strategic HR Review 17, no. 4 (2018): 198–203. http://dx.doi.org/10.1108/shr-05-2018-0040.

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Purpose The purpose of this paper is to aid employers and HR professionals in addressing the opioid epidemic, by examining the economic burden of addiction and its impact on the workplace, and it presents solutions based on a clinical approach to treatment and prevention of substance abuse. Design/methodology/approach The paper undertakes a review of current opioid addiction statistics provided by various professional organizations and the US government to assess the scope of opioid addiction and its effects on the US economy. Solutions to the growing issue of addiction are based on the author
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Higgins, Sheila A., and Jill Simons. "The Opioid Epidemic and the Role of the Occupational Health Nurse." Workplace Health & Safety 67, no. 1 (2018): 36–45. http://dx.doi.org/10.1177/2165079918796242.

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The opioid epidemic is a national public health crisis. It began with the misuse of commonly used prescription opioid pain relievers and has led to the increased use of heroin and illicit fentanyl. Large-scale initiatives have begun on the federal and state level and place an emphasis on improved opioid prescribing, which have important implications for the workplace. Treatment of work injury may initiate the use of prescription opioids and result in misuse and possible overdose. Prescription drug abuse affects all aspects of society so potentially any workplace could be affected. A multifacet
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K, El Safty, and Fouad M. "Impact of Opioid Toxicity on Workplace Productivity." Egyptian Journal of Occupational Medicine 44, no. 2 (2020): 577–88. http://dx.doi.org/10.21608/ejom.2020.109572.

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Paris, Julia, Caitlin Rowley, and Richerd Frank. "THE ECONOMIC IMPACT OF THE OPIOID EPIDEMIC." International Journal of Advanced Research in Accounting, Economics and Business Perspectives 7, no. 2 (2023): 42–48. http://dx.doi.org/10.48028/iiprds/ijaraebp.v7.i2.04.

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There is strong evidence that the opioid epidemic has reduced labor force participation in the United States. While use of prescription opioids aimed at pain management for some individuals may enhance their ability to work, the widespread misuse of opioids has resulted in an epidemic of opioid use disorders (OUD), labor supply disruptions, and unprecedented deaths. Opioid misuse can compromise labor supply in a variety of ways, including absenteeism, increased workplace accidents, and withdrawal from the labor force due to disability, incarceration, or death.
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Fang, Shenshen, Yinhang Wu, Zhiyu Liao, et al. "Application of Exercise Prescription in Corporate Health Management." Journal of Medicine and Physical Education 1, no. 4 (2024): 41–54. https://doi.org/10.62517/jmpe.202418407.

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Corporate health management has emerged as a pivotal strategic element in today's competitive business landscape, emphasizing the indispensable role of employee health in enhancing productivity and driving business success. Exercise prescription, tailored fitness programs designed specifically for individual employees, stands as a cornerstone of this holistic approach. By promoting regular physical activity, these programs not only improve the overall health and wellbeing of the workforce but also contribute to a more vibrant and engaged workplace culture. As a result, companies can expect to
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Dmytriiev, D. V., O. A. Zaletska, and D. I. Bortnik. "Opioids in the treatment of non-specific acute and chronic pain." Pain medicine 4, no. 1 (2019): 22–36. http://dx.doi.org/10.31636/pmjua.v4i1.3.

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After reading this article, the reader will be familiar with the general classes of opioid agonists and partial agonists, the basics of the pharmacokinetics and pharmacodynamics of opioids, the risks of opioid therapy and the requirements for the safe and effective use of opioids in acute and chronic pain. The use of opioids during surgical procedures or anesthesia is not discussed. Also, there is no discussion about various available opioid antagonists that are used to treat overdose and the various disorders associated with their use (including naloxone and naltrexone). Opioids are available
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Kowalski-McGraw, Michele, Judith Green-McKenzie, Sudha P. Pandalai, and Paul A. Schulte. "Characterizing the Interrelationships of Prescription Opioid and Benzodiazepine Drugs With Worker Health and Workplace Hazards." Journal of Occupational and Environmental Medicine 59, no. 11 (2017): 1114–26. http://dx.doi.org/10.1097/jom.0000000000001154.

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10

Stanos, S., C. Argoff, G. Irving, et al. "Workplace and nonworkplace productivity in chronic noncancer pain patients: the Opioid Utilization Study (OPUS)." Journal of Pain 10, no. 4 (2009): S49. http://dx.doi.org/10.1016/j.jpain.2009.01.205.

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Ho, Edward, Matthew Doherty, Robert Thomas, John Attia, Christopher Oldmeadow, and Matthew Clapham. "Prescription of opioids to post-operative orthopaedic patients at time of discharge from hospital: a prospective observational study." Scandinavian Journal of Pain 18, no. 2 (2018): 253–59. http://dx.doi.org/10.1515/sjpain-2017-0149.

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Abstract Background and aims: Excessive opioid prescribing can lead to adverse consequences including stockpiling, misuse, dependency, diversion and mortality. Increased prescriptions to post-operative inpatients as part of their discharge planning may be a significant contributor. Primary aims included comparing the amount of opioids prescribed, consumed, left unused and their relationship with pain and functionality. Methods: A total of 132 consecutive patients who underwent elective orthopaedic surgery were prospectively audited. Daily oral morphine equivalent (DME) of opioids prescribed wa
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Rogers, Andrew H., Jafar Bakhshaie, Michael F. Orr, Joseph W. Ditre, and Michael J. Zvolensky. "Health Literacy, Opioid Misuse, and Pain Experience Among Adults with Chronic Pain." Pain Medicine 21, no. 4 (2019): 670–76. http://dx.doi.org/10.1093/pm/pnz062.

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Abstract Background Chronic pain is a significant public health problem that is associated with several negative health outcomes, including increased health care cost, decreased productivity, and prescription opioid misuse. Although efforts have been made to curb the growing opioid epidemic in the United States, further research is needed to better understand individual difference factors that may be associated with greater pain and opioid misuse. Lower levels of health literacy, defined as the ability to obtain, understand, and use health information to make important decisions regarding heal
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13

Sjøgaard, Gisela, Karen Søgaard, Anne Faber Hansen, Anne Skov Østergaard, Sanel Teljigovic, and Tina Dalager. "Exercise Prescription for the Work–Life Population and Beyond." Journal of Functional Morphology and Kinesiology 8, no. 2 (2023): 73. http://dx.doi.org/10.3390/jfmk8020073.

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The background for this paper concerns a high frequency of work-related disorders that may result from physical exposure at work being highly sedentary, repetitive–monotonous, or physically demanding. This may result in levels of physical inactivity or strenuous activity impairing health. The aim is to present an evidence-based exercise prescription for the work–life population and beyond. The exercise program is designed to be feasible for use at the workplace and/or during leisure time and to improve health, workability, productivity, sickness absence, etc. The specific concept of Intelligen
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Mustard, Cameron, Victoria Nadalin, Nancy Carnide, Emile Tompa, and Peter Smith. "Cohort profile: the Ontario Life After Workplace Injury Study (OLAWIS)." BMJ Open 11, no. 9 (2021): e048143. http://dx.doi.org/10.1136/bmjopen-2020-048143.

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PurposeThe substantial economic burden of work-related injury and illness, borne by workers, employers and social security programmes, is primarily attributed to the durations of work disability among workers whose recovery requires a period of absence from work, with the majority of costs arising from the minority of workers with the longest duration absences. The objective of the Ontario Life After Workplace Injury Study is to describe the long-term health and labour market outcomes of workers disabled by work injury or illness after they are no longer receiving benefits or services from the
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Verma, Vikash, Sabita Jyoti, Mohan Belbase, et al. "Assessment of Prescribing Pattern of Antidepressants in Patient Suffering from Depressive Disorder Visiting the OPD at a Tertiary Care Teaching Hospital." Journal of Nepalgunj Medical College 22, no. 2 (2024): 18–21. https://doi.org/10.3126/jngmc.v22i2.74350.

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Introduction: Depression is a prevalent condition that strongly affects the quality of life, academic performance, social behavior, family life, and workplace productivity. Treatment of depression, is of paramount importance and it can be achieved by proper and judicious use of antidepressant drugs. Aims: To assess drug utilization patterns of antidepressant drug & their relevant classes to understand the drug practicing behavior of antidepressant drugs. Methods: A descriptive cross sectional study was conducted on 159 patients visiting outpatient Department of Psychiatry at Nepalgunj Medi
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Kaskie, Brian. "Comparing Cannabis Use Across Diagnosed Conditions: Apples and Oranges?" Innovation in Aging 5, Supplement_1 (2021): 509. http://dx.doi.org/10.1093/geroni/igab046.1965.

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Abstract Although researchers have identified medications that relieve symptoms of Multiple Sclerosis (MS), none are entirely effective and some persons with multiple sclerosis (PwMS) use alternatives. Our study compared cannabis use among PwMS (N=135) and persons diagnosed with arthritis (N=582) or cancer (N=622) who participated in the Illinois medical cannabis program. We tested for significant differences across psychological well-being, quality of life and three behavioral outcomes, and also considered effects of co-occurring prescription opioid use. A majority of all individuals used can
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Cernasev, Alina, Michael P. Veve, Taylor Talbott, Elizabeth A. Hall, and Kenneth C. Hohmeier. "Pharmacy Students’ Perceptions and Stigma Surrounding Naloxone Use in Patients with Opioid Use Disorder: A Mixed Methods Evaluation." Pharmacy 8, no. 4 (2020): 205. http://dx.doi.org/10.3390/pharmacy8040205.

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Pharmacists represent a key group of healthcare professionals that can increase awareness and destigmatize naloxone use. The objective of this study was to investigate pharmacy student perceptions of the use, dispensing, and stigma surrounding naloxone. An electronic survey was administered to pharmacy students that included questions about demographics, work history, naloxone use, and naloxone stigma. Separate qualitative interviews were performed to identify themes surrounding naloxone use. Two-hundred sixty-two participants completed the survey. The majority of participants were “highly wil
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Morrison, Umor Iwele. "The workplace and evolving ethics for worthwhile productivity in the education sector." GPH-International Journal of Educational Research 8, no. 01 (2025): 302–13. https://doi.org/10.5281/zenodo.14674704.

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Abstract This paper focused on the workplace and evolving ethics for worthwhile productivity with a focus on education. This becomes necessary because the education sector is bedevilled with several breaches ranging from insubordination, neglect of duty, physical confrontation, litigation, contempt of duty, examination fraud, misappropriation of funds, witch-hunting, the illegality of different magnitude and other forms of breaches. The paper explained basic concepts such as ethics, workplace ethics, leadership ethics, employees’ ethics, and morality. The project is that ethics are unive
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Hostland, C., R. Sadiq, G. Lovegrove, and D. Roberts. "HEALTH2: A Holistic Environmental Assessment Lay Tool for Home Health." Canadian Journal of Civil Engineering 42, no. 4 (2015): 241–49. http://dx.doi.org/10.1139/cjce-2014-0228.

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Although the adverse health effects of poor indoor air quality on occupants from mold and dampness in indoor environments are well described, there is no reliable empirical tool to evaluate indoor mold and dampness levels in the home for use by the medical profession and health safety regulatory bodies. The economic impact to society approaches $40 billion a year in North America alone from the cost of health care and workplace lost productivity. Mobilizing corrective action necessitates an acceptable home environment evaluation method. This paper proposes a reliable empirical model and tool,
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20

Ojo, Andrew, Steven Zhang, Nataly Bleibdrey, Dan Zimskind, Nasir Keshvani, and Rob Chalmers. "Persistence and switching patterns of migraine prophylactic medications in Canada: A retrospective claims analysis comparing adherence and evaluating the economic burden of illness." Journal of Pharmacy & Pharmaceutical Sciences 25 (January 7, 2023): 402–17. http://dx.doi.org/10.18433/jpps33158.

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Purpose: To describe patient characteristics, treatment patterns, and the burden of illness among adult migraine patients in Canada prescribed migraine prophylactics. Little is known about the relative persistence of treatments in the real-world setting and the impact of migraine prophylactic therapy on patients. As a result, migraine care in Canada continues to inadequately serve patients suffering from frequent headache days, reflecting a large unmet need. Methods: This retrospective study used Reformulary Group’s longitudinal prescription claims database. Private payer data were analyzed to
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Willer, Fiona, David Chua, and Lauren Ball. "Patient aggression towards receptionists in general practice: a systematic review." Family Medicine and Community Health 11, no. 3 (2023): e002171. http://dx.doi.org/10.1136/fmch-2023-002171.

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ObjectiveGeneral practice receptionists provide an essential function in the healthcare system but routinely encounter acts of incivility and aggression from patients, including hostility, abuse and violence. This study was conducted to summarise what is known about patient-initiated aggression towards general practice receptionists, including impacts on reception staff and existing mitigation strategies.DesignSystematic review with convergent integrated synthesis.Eligibility criteriaStudies published at any time in English that examine patient aggression experiences of reception staff in prim
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22

Wang, Carol Chunfeng, Lisa Whitehead, Travis Cruickshank, Johnny Lo, Jianhong (Cecilia) Xia, and Jun Wen. "Feasibility and therapeutic efficacy of a two-week low-level laser acupuncture therapy for shoulder and neck pain in office workers: Protocol for a pilot, single-blind, double-armed, randomised controlled trial." PLOS ONE 17, no. 1 (2022): e0260846. http://dx.doi.org/10.1371/journal.pone.0260846.

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Background Shoulder and neck pain (SNP) is common in office workers and represents a serious public health problem given its detrimental impact on quality of life, physical functioning, personal finances, employers, and the health care system. Management with painkillers has adverse implications such as tolerance, addiction, and opioid abuse. Safe, sustainable, cost-effective, and evidence-based solutions are urgently needed. The non-invasive, painless, non-infectious, and safe modality of low-level laser acupuncture (LLLA) has shown promise for SNP management. Objective The overarching aim of
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23

Novoderezhkina, Evgeniya A., and Sergey K. Zyryanov. "Estimating the indirect costs associated with psoriasis." Kazan medical journal 103, no. 5 (2022): 824–31. http://dx.doi.org/10.17816/kmj2022-824.

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Background. The assessment of indirect economic costs associated with psoriasis is relevant due to the poor knowledge of the impact of the disease on key performance indicators, as well as the question of how the expansion of the pool of patients receiving genetically engineered biological drugs affects the indirect costs associated with the disease.
 Aim. Evaluation of the indirect economic burden of psoriasis associated with missed work time and reduced performance in the actual presence at the workplace, as well as an assessment of the impact of changing the structure of therapy on ind
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Johnson, G., K. Hickey, A. Azin, et al. "2021 Canadian Surgery Forum01. Design and validation of a unique endoscopy simulator using a commercial video game03. Is ethnicity an appropriate measure of health care marginalization?: A systematic review and meta-analysis of the outcomes of diabetic foot ulceration in the Aboriginal population04. Racial disparities in surgery — a cross-specialty matched comparison between black and white patients05. Starting late does not increase the risk of postoperative complications in patients undergoing common general surgical procedures06. Ethical decision-making during a health care crisis: a resource allocation framework and tool07. Ensuring stability in surgical training program leadership: a survey of program directors08. Introducing oncoplastic breast surgery in a community hospital09. Leadership development programs for surgical residents: a review of the literature10. Superiority of non-opioid postoperative pain management after thyroid and parathyroid operations: a systematic review and meta-analysis11. Timing of ERCP relative to cholecystectomy in patients with ductal gallstone disease12. A systematic review and meta-analysis of randomized controlled trials comparing intraoperative red blood cell transfusion strategies13. Postoperative outcomes after frail elderly preoperative assessment clinic: a single-institution Canadian perspective14. Selective opioid antagonists following bowel resection for prevention of postoperative ileus: a systematic review and meta-analysis15. Peer-to-peer coaching after bile duct injury16. Laparoscopic median arcuate ligament release: a video abstract17. Retroperitoneoscopic approach to adrenalectomy19. Endoscopic Zenker diverticulotomy: a video abstract20. Variability in surgeons’ perioperative management of pheochromocytomas in Canada21. The contribution of surgeon and hospital variation in transfusion practice to outcomes for patients undergoing elective gastrointestinal cancer surgery: a population-based analysis22. Perioperative transfusions for gastroesophageal cancers: risk factors and short- and long-term outcomes23. The association between frailty and time alive and at home after cancer surgery among older adults: a population-based analysis24. Psychological and workplace-related effects of providing surgical care during the COVID-19 pandemic in British Columbia, Canada25. Safety of venous thromboembolism prophylaxis in endoscopic retrograde cholangiopancreatography: a systematic review26. Complications and reintervention following laparoscopic subtotal cholecystectomy: a systematic review and meta-analysis27. Synchronization of pupil dilations correlates with team performance in a simulated laparoscopic team coordination task28. Receptivity to and desired design features of a surgical peer coaching program: an international survey9. Impact of the COVID-19 pandemic on rates of emergency department utilization due to general surgery conditions30. The impact of the current COVID-19 pandemic on the exposure of general surgery trainees to operative procedures31. Association between academic degrees and research productivity: an assessment of academic general surgeons in Canada32. Laparoscopic endoscopic cooperative surgery (LECS) for subepithelial gastric lesion: a video presentation33. Effect of the COVID-19 pandemic on acute care general surgery at an academic Canadian centre34. Opioid-free analgesia after outpatient general surgery: a pilot randomized controlled trial35. Impact of neoadjuvant immunotherapy or targeted therapies on surgical resection in patients with solid tumours: a systematic review and meta-analysis37. Surgical data recording in the operating room: a systematic review of modalities and metrics38. Association between nonaccidental trauma and neighbourhood socioeconomic status during the COVID-19 pandemic: a retrospective analysis39. Laparoscopic repair of a transdiaphragmatic gastropleural fistula40. Video-based interviewing in medicine: a scoping review41. Indocyanine green fluorescence angiography for prevention of anastomotic leakage in colorectal surgery: a cost analysis from the hospital payer’s perspective43. Perception or reality: surgical resident and faculty assessments of resident workload compared with objective data45. When illness and loss hit close to home: Do health care providers learn how to cope?46. Remote video-based suturing education with smartphones (REVISE): a randomized controlled trial47. The evolving use of robotic surgery: a population-based analysis48. Prophylactic retromuscular mesh placement for parastomal hernia prevention: a retrospective cohort study of permanent colostomies and ileostomies49. Intracorporeal versus extracorporeal anastomosis in laparoscopic right hemicolectomy: a retrospective cohort study on anastomotic complications50. A lay of the land — a description of Canadian academic acute care surgery models51. Emergency general surgery in Ontario: interhospital variability in structures, processes and models of care52. Trauma 101: a virtual case-based trauma conference as an adjunct to medical education53. Assessment of the National Surgical Quality Improvement Program Surgical Risk Calculator for predicting patient-centred outcomes of emergency general surgery patients in a Canadian health care system54. Sustainability of a narcotic reduction initiative: 1 year following the Standardization of Outpatient Procedure (STOP) Narcotics Study55. Barriers to transanal endoscopic microsurgery referral56. Geospatial analysis of severely injured rural patients in a geographically complex landscape57. Implementation of an incentive spirometry protocol in a trauma ward: a single-centre pilot study58. Impostor phenomenon is a significant risk factor for burnout and anxiety in Canadian resident physicians: a cross-sectional survey59. Understanding the influence of perioperative education on performance among surgical trainees: a single-centre experience60. The effect of COVID-19 pandemic on current and future endoscopic personal protective equipment practices: a national survey of 77 endoscopists61. Case report: delayed presentation of perforated sigmoid diverticulitis as necrotizing infection of the lower limb62. Investigating disparities in surgical outcomes in Canadian Indigenous populations63. Fundoplication is superior to medical therapy for Barrett esophagus disease regression and progression: a systematic review and meta-analysis64. Development of a novel online general surgery learning platform and a qualitative preimplementation analysis65. Hagfish slime exudate as a potential novel hemostatic agent: developing a standardized assessment protocol66. The effect of the first wave of the COVID-19 pandemic on surgical oncology case volumes and wait times67. Safety of same-day discharge in high-risk patients undergoing ambulatory general surgery68. External validation of the Codman score in colorectal surgery: a pragmatic tool to drive quality improvement69. Improved morbidity and gastrointestinal restoration rates without compromising survival rates for diverting loop ileostomy with colonic lavage versus total abdominal colectomy for fulminant Clostridioides difficile colitis: a multicentre retrospective cohort study70. Potential access to emergency general surgical care in Ontario71. Immersive virtual reality (iVR) improves procedural duration, task completion and accuracy in surgical trainees: a systematic review01. Clinical validation of the Canada Lymph Node Score for endobronchial ultrasound02. Venous thromboembolism in surgically treated esophageal cancer patients: a provincial population-based study03. Venous thromboembolism in surgically treated lung cancer patients: a population-based study04. Is frailty associated with failure to rescue after esophagectomy? A multi-institutional comparative analysis of outcomes05. Routine systematic sampling versus targeted sampling of lymph nodes during endobronchial ultrasound: a feasibility randomized controlled trial06. Gastric ischemic conditioning reduces anastomotic complications in patients undergoing esophagectomy: a systematic review and meta-analysis07. Move For Surgery, a novel preconditioning program to optimize health before thoracic surgery: a randomized controlled trial08. In case of emergency, go to your nearest emergency department — Or maybe not?09. Does preoperative SABR increase the risk of complications from lung cancer resection? A secondary analysis of the MISSILE trial10. Segmental resection for lung cancer: the added value of near-infrared fluorescence mapping diminishes with surgeon experience11. Toward competency-based continuing professional development for practising surgeons12. Stereotactic body radiotherapy versus surgery in older adults with NSCLC — a population-based, matched analysis of long-term dependency outcomes13. Role of adjuvant therapy in esophageal cancer patients after neoadjuvant therapy and curative esophagectomy: a systematic review and meta-analysis14. Evaluation of population characteristics on the incidence of thoracic empyema: an ecological study15. Determining the optimal stiffness colour threshold and stiffness area ratio cut-off for mediastinal lymph node staging using EBUS elastography and AI: a pilot study16. Quality assurance on the use of sequential compression stockings in thoracic surgery (QUESTs)17. The relationship between fissureless technique and prolonged air leak for patients undergoing video-assisted thoracoscopic lobectomy18. CXCR2 inhibition as a candidate for immunomodulation in the treatment of K-RAS-driven lung adenocarcinoma19. Assessment tools for evaluating competency in video-assisted thoracoscopic lobectomy: a systematic review20. Understanding the current practice on chest tube management following lung resection among thoracic surgeons across Canada21. Effect of routine jejunostomy tube insertion in esophagectomy: a systematic review and meta-analysis22. Recurrence of primary spontaneous pneumothorax following bullectomy with pleurodesis or pleurectomy: a retrospective analysis23. Surgical outcomes following chest wall resection and reconstruction24. Outcomes following surgical management of primary mediastinal nonseminomatous germ cell tumours25. Does robotic approach offer better nodal staging than thoracoscopic approach in anatomical resection for non–small cell lung cancer? A single-centre propensity matching analysis26. Competency assessment for mediastinal mass resection and thymectomy: design and Delphi process27. The contemporary significance of venous thromboembolism (deep venous thrombosis [DVT] and pulmonary embolus [PE]) in patients undergoing esophagectomy: a prospective, multicentre cohort study to evaluate the incidence and clinical outcomes of VTE after major esophageal resections28. Esophageal cancer: symptom severity at the end of life29. The impact of pulmonary artery reconstruction on postoperative and oncologic outcomes: a systematic review30. Association with surgical technique and recurrence after laparoscopic repair of paraesophageal hernia: a single-centre experience31. Enhanced recovery after surgery (ERAS) in esophagectomy32. Surgical treatment of esophageal cancer: trends in surgical approach and early mortality at a single institution over the past 18 years34. Adverse events and length of stay following minimally invasive surgery in paraesophageal hernia repair35. Long-term symptom control comparison of Dor and Nissen fundoplication following laparoscopic para-esophageal hernia repair: a retrospective analysis36. Willingness to pay: a survey of Canadian patients’ willingness to contribute to the cost of robotic thoracic surgery37. Radiomics in early-stage lung adenocarcinoma: a prediction tool for tumour immune microenvironments38. Effectiveness of intraoperative pyloric botox injection during esophagectomy: how often is endoscopic intervention required?39. An artificial intelligence algorithm for predicting lymph node malignancy during endobronchial ultrasound40. The effect of major and minor complications after lung surgery on length of stay and readmission41. Measuring cost of adverse events following thoracic surgery: a scoping review42. Laparoscopic paraesophageal hernia repair: characterization by hospital and surgeon volume and impact on outcomes43. NSQIP 5-Factor Modified Frailty Index predicts morbidity but not mortality after esophagectomy44. Trajectory of perioperative HRQOL and association with postoperative complications in thoracic surgery patients45. Variation in treatment patterns and outcomes for resected esophageal cancer at designated thoracic surgery centres46. Patient-reported pretreatment health-related quality of life (HRQOL) predicts short-term survival in esophageal cancer patients47. Analgesic efficacy of surgeon-placed paravertebral catheters compared with thoracic epidural analgesia after Ivor Lewis esophagectomy: a retrospective noninferiority study48. Rapid return to normal oxygenation after lung surgery49. Examination of local and systemic inflammatory changes during lung surgery01. Implications of near-infrared imaging and indocyanine green on anastomotic leaks following colorectal surgery: a systematic review and meta-analysis02. Repeat preoperative endoscopy after regional implementation of electronic synoptic endoscopy reporting: a retrospective comparative study03. Consensus-derived quality indicators for operative reporting in transanal endoscopic surgery (TES)04. Colorectal lesion localization practices at endoscopy to facilitate surgical and endoscopic planning: recommendations from a national consensus Delphi process05. Black race is associated with increased mortality in colon cancer — a population-based and propensity-score matched analysis06. Improved survival in a cohort of patients 75 years and over with FIT-detected colorectal neoplasms07. Laparoscopic versus open loop ileostomy reversal: a systematic review and meta-analysis08. Posterior mesorectal thickness as a predictor of increased operative time in rectal cancer surgery: a retrospective cohort study09. Improvement of colonic anastomotic healing in mice with oral supplementation of oligosaccharides10. How can we better identify patients with rectal bleeding who are at high risk of colorectal cancer?11. Assessment of long-term bowel dysfunction in rectal cancer survivors: a population-based cohort study12. Observational versus antibiotic therapy for acute uncomplicated diverticulitis: a noninferiority meta-analysis based on a Delphi consensus13. Radiotherapy alone versus chemoradiotherapy for stage I anal squamous cell carcinoma: a systematic review and meta-analysis14. Is the Hartmann procedure for diverticulitis obsolete? National trends in colectomy for diverticulitis in the emergency setting from 1993 to 201515. Sugammadex in colorectal surgery: a systematic review and meta-analysis16. Sexuality and rectal cancer treatment: a qualitative study exploring patients’ information needs and expectations on sexual dysfunction after rectal cancer treatment17. Video-based interviews in selection process18. Impact of delaying colonoscopies during the COVID-19 pandemic on colorectal cancer detection and prevention19. Opioid use disorder associated with increased anastomotic leak and major complications after colorectal surgery20. Effectiveness of a rectal cancer education video on patient expectations21. Robotic-assisted rectosigmoid and rectal cancer resection: implementation and early experience at a Canadian tertiary centre22. An online educational app for rectal cancer survivors with low anterior resection syndrome: a pilot study23. The effects of surgeon specialization on the outcome of emergency colorectal surgery24. Outcomes after colorectal cancer resections in octogenarians and older in a regional New Zealand setting — What are the predictors of mortality?25. Long-term outcomes after seton placement for perianal fistulae with and without Crohn disease26. A survey of patient and surgeon preference for early ileostomy closure following restorative proctectomy for rectal cancer — Why aren’t we doing it?27. Crohn disease independently associated with longer hospital admission after surgery28. Short-stay (≤ 1 d) diverting loop ileostomy closure can be selectively implemented without an increase in readmission and complication rates: an ACS-NSQIP analysis29. A comparison of perineal stapled rectal prolapse resection and the Altemeier procedure at 2 Canadian academic hospitals30. Mental health and substance use disorders predict 90-day readmission and postoperative complications following rectal cancer surgery31. Early discharge after colorectal cancer resection: trends and impact on patient outcomes32. Oral antibiotics without mechanical bowel preparation prior to emergency colectomy reduces the risk of organ space surgical site infections: a NSQIP propensity score matched study33. The impact of robotic surgery on a tertiary care colorectal surgery program, an assessment of costs and short-term outcomes — a Canadian perspective34. Should we scope beyond the age limit of guidelines? Adenoma detection rates and outcomes of screening and surveillance colonoscopies in patients aged 75–79 years35. Emergency department admissions for uncomplicated diverticulitis: a nationwide study36. Obesity is associated with a complicated episode of acute diverticulitis: a nationwide study37. Green indocyanine angiography for low anterior resection in patients with rectal cancer: a prospective before-and-after study38. The impact of age on surgical recurrence of fibrostenotic ileocolic Crohn disease39. A qualitative study to explore the optimal timing and approach for the LARS discussion01. Racial, ethnic and socioeconomic disparities in diagnosis, treatment and survival of patients with breast cancer: a SEER-based population analysis02. First-line palliative chemotherapy for esophageal and gastric cancer: practice patterns and outcomes in the general population03. Frailty as a predictor for postoperative outcomes following pancreaticoduodenectomy04. Synoptic electronic operative reports identify practice variation in cancer surgery allowing for directed interventions to decrease variation05. The role of Hedgehog signalling in basal-like breast cancer07. Clinical and patient-reported outcomes in oncoplastic breast conservation surgery from a single surgeon’s practice in a busy community hospital in Canada08. Upgrade rate of atypical ductal hyperplasia: 10 years of experience and predictive factors09. Time to first adjuvant treatment after oncoplastic breast reduction10. Preparing to survive: improving outcomes for young women with breast cancer11. Opioid prescription and consumption in patients undergoing outpatient breast surgery — baseline data for a quality improvement initiative12. Rectal anastomosis and hyperthermic intraperitoneal chemotherapy: Should we avoid diverting loop ileostomy?13. Delays in operative management of early-stage, estrogen-receptor positive breast cancer during the COVID-19 pandemic — a multi-institutional matched historical cohort study14. Opioid prescribing practices in breast oncologic surgery15. Oncoplastic breast reduction (OBR) complications and patient-reported outcomes16. De-escalating breast cancer surgery: Should we apply quality indicators from other jurisdictions in Canada?17. The breast cancer patient experience of telemedicine during COVID-1918. A novel ex vivo human peritoneal model to investigate mechanisms of peritoneal metastasis in gastric adenocarcinoma (GCa)19. Preliminary uptake and outcomes utilizing the BREAST-Q patient-reported outcomes questionnaire in patients following breast cancer surgery20. Routine elastin staining improves detection of venous invasion and enhances prognostication in resected colorectal cancer21. Analysis of exhaled volatile organic compounds: a new frontier in colon cancer screening and surveillance22. A clinical pathway for radical cystectomy leads to a shorter hospital stay and decreases 30-day postoperative complications: a NSQIP analysis23. Fertility preservation in young breast cancer patients: a population-based study24. Investigating factors associated with postmastectomy unplanned emergency department visits: a population-based analysis25. Impact of patient, tumour and treatment factors on psychosocial outcomes after treatment in women with invasive breast cancer26. The relationship between breast and axillary pathologic complete response in women receiving neoadjuvant chemotherapy for breast cancer01. The association between bacterobilia and the risk of postoperative complications following pancreaticoduodenectomy02. Surgical outcome and quality of life following exercise-based prehabilitation for hepatobiliary surgery: a systematic review and meta-analysis03. Does intraoperative frozen section and revision of margins lead to improved survival in patients undergoing resection of perihilar cholangiocarcinoma? A systematic review and meta-analysis04. Prolonged kidney procurement time is associated with worse graft survival after transplantation05. Venous thromboembolism following hepatectomy for colorectal metastases: a population-based retrospective cohort study06. Association between resection approach and transfusion exposure in liver resection for gastrointestinal cancer07. The association between surgeon volume and use of laparoscopic liver resection for gastrointestinal cancer08. Immune suppression through TIGIT in colorectal cancer liver metastases09. “The whole is greater than the sum of its parts” — a combined strategy to reduce postoperative pancreatic fistula after pancreaticoduodenectomy10. Laparoscopic versus open synchronous colorectal and hepatic resection for metastatic colorectal cancer11. Identifying prognostic factors for overall survival in patients with recurrent disease following liver resection for colorectal cancer metastasis12. Modified Blumgart pancreatojejunostomy with external stenting in laparoscopic Whipple reconstruction13. Laparoscopic versus open pancreaticoduodenectomy: a single centre’s initial experience with introduction of a novel surgical approach14. Neoadjuvant chemotherapy versus upfront surgery for borderline resectable pancreatic cancer: a single-centre cohort analysis15. Thermal ablation and telemedicine to reduce resource utilization during the COVID-19 pandemic16. Cost-utility analysis of normothermic machine perfusion compared with static cold storage in liver transplantation in the Canadian setting17. Impact of adjuvant therapy on overall survival in early-stage ampullary cancers: a single-centre retrospective review18. Presence of biliary anaerobes enhances response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma19. How does tumour viability influence the predictive capability of the Metroticket model? Comparing predicted-to-observed 5-year survival after liver transplant for hepatocellular carcinoma20. Does caudate resection improve outcomes in patients undergoing curative resection for perihilar cholangiocarcinoma? A systematic review and meta-analysis21. Appraisal of multivariable prognostic models for postoperative liver decompensation following partial hepatectomy: a systematic review22. Predictors of postoperative liver decompensation events following resection in patients with cirrhosis and hepatocellular carcinoma: a population-based study23. Characteristics of bacteriobilia and impact on outcomes after Whipple procedure01. Inverting the y-axis: the future of MIS abdominal wall reconstruction is upside down02. Progressive preoperative pneumoperitoneum: a single-centre retrospective study03. The role of radiologic classification of parastomal hernia as a predictor of the need for surgical hernia repair: a retrospective cohort study04. Comparison of 2 fascial defect closure methods for laparoscopic incisional hernia repair01. Hypoalbuminemia predicts serious complications following elective bariatric surgery02. Laparoscopic adjustable gastric band migration inducing jejunal obstruction associated with acute pancreatitis: aurgical approach of band removal03. Can visceral adipose tissue gene expression determine metabolic outcomes after bariatric surgery?04. Improvement of kidney function in patients with chronic kidney disease and severe obesity after bariatric surgery: a systematic review and meta-analysis05. A prediction model for delayed discharge following gastric bypass surgery06. Experiences and outcomes of Indigenous patients undergoing bariatric surgery: a mixed-methods scoping review07. What is the optimal common channel length in revisional bariatric surgery?08. Laparoscopic management of internal hernia in a 34-week pregnant woman09. Characterizing timing of postoperative complications following elective Roux-en-Y gastric bypass and sleeve gastrectomy10. Canadian trends in bariatric surgery11. Common surgical stapler problems and how to correct them12. Management of choledocholithiasis following Roux-en-Y gastric bypass: a systematic review and meta-analysis." Canadian Journal of Surgery 64, no. 6 Suppl 2 (2021): S80—S159. http://dx.doi.org/10.1503/cjs.021321.

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25

Paulsen, Ryan B., Michael I. Schaffer, and G. Neil Stowe. "Opioid Hair Concentrations Using Retrospective Prescription Data From a United States Workplace Testing Population." Journal of Analytical Toxicology, January 2, 2025. https://doi.org/10.1093/jat/bkae101.

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Abstract Opioids are widely prescribed pain medications that have the potential for misuse and abuse. As part of a routine procedure, our laboratory frequently encounters questions from clients/Medical Review Officers (MROs) regarding opioid hair concentrations in relation to the amount of opioid taken as part of a prescription. In this manuscript, we have analyzed a large number of real-world examples of opioid hair concentrations following self-reported consumption of an opioid prescription regimen. This dataset provides a reference point of opioid hair concentrations after an extensive aque
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26

Le, Aurora B., and Jonathan D. Rosen. "It Is Time to Implement Primary Prevention in the Workplace to Ameliorate the Ongoing U.S. Opioid Epidemic." NEW SOLUTIONS: A Journal of Environmental and Occupational Health Policy, August 25, 2021, 104829112110398. http://dx.doi.org/10.1177/10482911211039880.

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The United States’ opioid public health crisis continues having disastrous consequences on communities, including workers and employers. From May 2019 to May 2020, the largest number of drug overdose deaths was recorded over a twelve-month period. The “twindemics” of COVID-19 and opioids underscore the urgent need to address workers’ physical and mental health. Although much has been written about the negative impacts of the opioid epidemic on the workplace, few initiatives have focused on primary prevention, addressing work-related root causes of opioid use disorders (e.g., injury, stress) th
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Weaver, GracieLee, William B. Hansen, Scarlett Ruppert, et al. "Effects of Workplace Variables on Workers Intentions to Misuse Prescription Opioids." Journal of Occupational & Environmental Medicine, August 28, 2023. http://dx.doi.org/10.1097/jom.0000000000002956.

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Abstract Objective Workers in industries with high rates of opioid dispensing as well as those with high rates of non-fatal work-related injuries are at greater risk for opioid misuse, which can lead to addiction, overdose, or death. Methods Using secondary cross-sectional data collected from 856 healthcare workers, this pilot study examines a conceptual model for workers’ intentions to seek out prescription opioids and intentions to use opioids at higher doses over longer periods of time. Results Results showed significant protective effects of Beliefs, Injunctive and Subjective Norms, and Be
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28

Thornton, J. Douglas, Tyler Varisco, Prachet Bhatt, Olajumoke Olateju, Mina Shrestha, and Chan Shen. "Productivity Loss Among Opioid and Benzodiazepine Users in the United States: A Medical Expenditure Panel Survey from 2010-2019." Journal of Occupational & Environmental Medicine, December 14, 2023. http://dx.doi.org/10.1097/jom.0000000000003029.

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Abstract Objective To estimate the association between productivity losses and the use of prescription opioids and benzodiazepines among employed US adults with painful conditions. Methods Using Medical Expenditures Panel Survey (2010-2019), we employed two-part (logistic regression and generalized linear model with zero-truncated negative binomial link) model to compare missed workdays due to illness or injury among employed adults with a painful condition. Results Of the eligible sample of 57,413 working US individuals, 14.65% were prescription opioid users, 2.95% were benzodiazepine users,
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"A Public Health Approach to Protecting Workers from Opioid Use Disorder and Overdose Related to Occupational Exposure, Injury, and Stress." NEW SOLUTIONS: A Journal of Environmental and Occupational Health Policy, July 6, 2021, 104829112110310. http://dx.doi.org/10.1177/10482911211031012.

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Opioid overdose mortality, in combination with increased deaths from alcohol and suicide, is having a profound impact on American workplaces, compromising occupational health and safety and increasing workers’ compensation and health insurance costs, absenteeism, and lost productivity. The President’s Council of Economic Advisers estimates that more than 1 million workers are out of the workforce due to the opioid crisis. The impact on workers is equally profound, including job loss, divorce and family disruption, and potentially imprisonment, injury, illness, and death. Pain from occupational
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Sloan, MD, Paul A., and Mellar P. Davis, MD, FCCP. "Extended-Release and Long-Acting Opioids for Chronic Pain Management." Journal of Opioid Management 10, no. 7 (2023). http://dx.doi.org/10.5055/jom.2014.0228.

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Chronic pain from both cancer and noncancer sources affects approximately one quarter of the adult population in the United States. In addition to the considerable health burden, there is the burden of the patient suffering, loss of work productivity, and loss of social effectiveness for many patients. Untreated chronic pain has been documented to interfere with sleep patterns, increase anxiety and depression, decrease quality of life, and interfere with social relationships and the ability of a patient to cope with life. Long-term opioid therapy for the management of chronic-nonmalignant pain
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31

Shabet, Christina Lynn, Dominic Alessio, Brooke Kenney, Mark C. Bicket, Chad M. Brummett, and Jennifer F. Waljee. "Impact of preoperative opioid exposure on cost of care and workplace productivity loss after elective surgery." Regional Anesthesia & Pain Medicine, January 31, 2025, rapm—2024–106199. https://doi.org/10.1136/rapm-2024-106199.

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IntroductionA high proportion of surgical patients has previous opioid exposure, which is associated with poorer recovery and increased morbidity. However, much less is known regarding the direct and indirect costs that are associated with healthcare utilization among individuals on preoperative opioid therapy.MethodsWe analyzed The Merative MarketScan Commercial Database linked with the Merative MarketScan Health and Productivity Management Database to include all adult patients admitted and discharged from common elective surgeries between January 1, 2018 and June 30, 2021. Patients were clu
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Park, Joohyun, Elizabeth Bigman, and Ping Zhang. "Productivity Loss and Medical Costs Associated With Type 2 Diabetes Among Employees Aged 18–64 Years With Large Employer-Sponsored Insurance." Diabetes Care, September 1, 2022. http://dx.doi.org/10.2337/dc22-0445.

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OBJECTIVE To estimate productivity losses and costs and medical costs due to type 2 diabetes (T2D) among employees aged 18–64 years. RESEARCH DESIGN AND METHODS Using 2018–2019 MarketScan databases, we identified employees with T2D or no diabetes among those with records on workplace absences, short-term disability (STD), and long-term disability (LTD). We estimated per capita mean annual time loss attributable to T2D and its associated costs, calculated by multiplying time loss by average hourly wage. We estimated direct medical costs of T2D in total and by service type (inpatient, outpatient
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"Urine Drug Testing in Pain Medicine." Toxicology and Applied Pharmacology Insights 6, no. 1 (2023). http://dx.doi.org/10.33140/tapi.06.01.05.

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The recent Institute of Medicine report declared that greater than 100 million Americans have chronic pain with an associated cost of up to $635 billion each year due to medical treatment and lost productivity.[1,2] The explosion in opioid prescribing since the 1990s has resulted in opioids being the most frequently prescribed medication in the United States.[3–5] Manchikanti et al.'s study revealed a 149% increase in retail opioid sales and a 402% increase in average sales of opioids per person in the United States from 1997 to 2007 [6]. Looking at 1999–2012, the National Center for Health St
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Kiriazopoulos, Stefanie, Jason Perepelkin, and Heather Alford. "Prescription for change: Unveiling burnout perspectives among pharmacy leaders." Canadian Pharmacists Journal / Revue des Pharmaciens du Canada, November 29, 2024. https://doi.org/10.1177/17151635241293785.

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Background: Burnout among pharmacists is increasingly pertinent, with growing demand for effective interventions. Burnout can lead to reduced productivity, increased job turnover, medical errors, poor patient satisfaction, and other negative outcomes for patients and providers. Growing attention to burnout in the pharmacy profession highlights the need for personal, organizational, and systemic solutions. However, the uptake and relative efficacy of different approaches remain unclear, particularly within community pharmacy practice. This study sought the viewpoint of community pharmacy leader
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de Villiers, Elsje, and Nicholas Shenker. "OA07 What is effective pain management: an illustrative case report?" Rheumatology Advances in Practice 6, Supplement_1 (2022). http://dx.doi.org/10.1093/rap/rkac066.007.

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Abstract Introduction/Background Pain is a sensory and emotional experience perceived in terms of tissue damage and expressed in terms of altered behaviour. Chronic, medically unexplained pain is complex, disabling and common. It is important to rule out medical or modifiable causes, but most tests will not result in significant changes in management nor prognosis. Attempting rehabilitation before the patient narrative has been fully explained usually leads to a lack of progress. Sleep deprivation is important to acknowledge and restorative sleep has analgesic and fatigue-improving properties.
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