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Dissertations / Theses on the topic 'Optical coherence tomography'

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1

Huang, David. "Optical coherence tomography." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/12675.

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2

Muscat, Sarah. "Optical coherence tomography." Thesis, Connect to e-thesis, 2003. http://theses.gla.ac.uk/630/.

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Thesis (Ph.D.) - University of Glasgow, 2003.<br>Ph.D. thesis submitted to the Department of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, 2003. Includes bibliographical references. Print version also available.
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3

Xu, Weiming. "Offset Optical Coherence Tomography." Miami University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=miami1626870603439104.

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4

Akcay, Avni Ceyhun. "System design and optimization of optical coherence tomography." Doctoral diss., University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3586.

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Optical coherence imaging, including tomography (OCT) and microscopy (OCM), has been a growing research field in biomedical optical imaging in the last decade. In this imaging modality, a broadband light source, thus of short temporal coherence length, is used to perform imaging via interferometry. A challenge in optical coherence imaging, as in any imaging system towards biomedical diagnosis, is the quantification of image quality and optimization of the system components, both a primary focus of this research. We concentrated our efforts on the optimization of the imaging system from two mai
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5

Malmström, Mikael. "Multi-angle Oblique Optical Coherence Tomography." Thesis, KTH, Laserfysik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-72978.

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Optical Coherence Tomography (OCT) is a non-invasive high-resolutionmethod for measuring the reectance of scattering media in 1/2/3D, e.g.skin. The method has been used in a number of dierent medical elds andfor measurement of tissue optical properties.The software developed in this thesis is able to display features hidden ina shadowed volume by adding multiple OCT measurements taken at obliqueangles, a technique here called Multiple-Angle Oblique Optical CoherenceTomography (MAO-OCT).Three dierent objects with were measured at 5 to 9 angles. The measurementswere automatically and manually al
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6

Alex, Aneesh. "Multispectral three-dimensional optical coherence tomography." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/54164/.

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A spectral-domain OCT system operating at 1300 nm wavelength region, capable of acquiring 47,000 A-lines/s, was designed and developed. Its axial and transverse resolutions were &sim; 6 &micro;m and &sim;15 &micro;m respectively. OCT images of human skin were obtained in vivo using three OCT systems, in order to find the optimal wavelength region for dermal imaging. 800 nm OCT system provided better image contrast over other two wavelength regions. Meanwhile, 1300 nm wavelength region was needed to obtain information from deeper dermal layers. To determine the effect of melanin pigmentation on
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7

Hee, Michael Richard. "Optical coherence tomography of the eye." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/10263.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.<br>Includes bibliographical references (p. 221-230).<br>by Michael Richard Hee.<br>Ph.D.
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8

Valdez, Ashley. "Snapshot Spectral Domain Optical Coherence Tomography." Thesis, The University of Arizona, 2016. http://hdl.handle.net/10150/613413.

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Optical coherence tomography systems are used to image the retina in 3D to allow ophthalmologists diagnose ocular disease. These systems yield large data sets that are often labor-intensive to analyze and require significant expertise in order to draw conclusions, especially when used over time to monitor disease progression. Spectral Domain Optical Coherence Tomography (SD-OCT) instantly acquires depth profiles at a single location with a broadband source. These systems require mechanical scanning to generate two- or three-dimensional images. Instead of mechanically scanning, a beamlet array
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9

Wang, Zhao. "Intravascular Optical Coherence Tomography Image Analysis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1364673682.

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10

Beitel, David. "Development of optical sources for optical coherence tomography." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112557.

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The development of two different classes of optical sources for TD-OCT and FD-OCT are presented in this thesis. The design of several low-cost, high-performance BBSs, based on the ASE of two SOAs and EDF, are presented. Two different configuration types that were designed in this thesis are found to be effective BBSs. These sources are implemented in a TD-OCT system and therefore imaging performance is discussed as well. Secondly, two different WSSs based on mode-locked SFRLs with applications in SS-OCT are presented.<br>From our experimental results with BBSs, we conclude that: (1) S/C-band o
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11

Silva, K. K. M. Buddhika Dilusha. "Optical coherence tomography : technology enhancements and novel applications." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2004. http://theses.library.uwa.edu.au/adt-WU2005.0087.

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In the last fifteen years, a great deal of effort has been put forth, worldwide, for investigating and enhancing various aspects of optical coherence tomography (OCT). This thesis begins with a description of the technique of OCT, and an analysis of its underlying theory. The design and construction of an OCT system is described, with particular emphasis on a novel delay scanning method, and novel signal processing. Application of OCT to non-destructive characterisation of seeds, examination of skin lesions, measurement of fluid flow, and refractive index determination, are then demonstrate
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Armstrong, Julian. "Anatomical optical coherence tomography in the human upper airway." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0022.

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[Truncated abstract] This thesis describes the development, clinical validation and initial application of a technique for taking measurements of the shape and dimensions of the human upper airway, called anatomical optical coherence tomography (aOCT). The technique uses a transparent catheter containing a rotating optical probe which is introduced transnasally and positioned in the airway and oesophagus. Optical coherence tomography is used to take calibrated cross-sectional images of the airway lumen as the probe rotates. The probe can also be advanced or withdrawn within the catheter during
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13

Zuluaga, Andrés Felipe. "Contrast agents for tumor detection with optical coherence tomography /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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14

Alarousu, E. (Erkki). "Low coherence interferometry and optical coherence tomography in paper measurements." Doctoral thesis, University of Oulu, 2006. http://urn.fi/urn:isbn:9514282140.

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Abstract This thesis describes the application of Low Coherence Interferometry (LCI) and Optical Coherence Tomography (OCT) in paper measurements. The developed measurement system is a combination of a profilometer and a tomographic imaging device, which makes the construction versatile and applicable in several paper measurement applications. The developed system was first used to measure the surface structure of paper. Different grades of paper were selected to provide maximum variation in surface structure. The results show that the developed system is capable of measuring grades of paper
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15

Trifanov, Irina. "Fibre optical sources and systems for optical coherence tomography." Thesis, University of Kent, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593914.

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Optical Coherence Tomography (OCT) is a powerful imaging technology in biomedical research and medicine. It enables in situ. 3D visualization of tissue structure and pathology, without the need. to excise the tissue and resolution approaching that of histology. OCT has had the most clinical impact in ophthalmology, where it provides structural and quantit ative informat ion that cannot be obtained by any other modality. The objective of the work presented in this thesis was the development of new imaging methods and optical devices to progress the OCT technology in t erms of its versatility, a
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16

Meemon, Panomsak. "Development of optical coherence tomography for tissue diagnostics." Doctoral diss., University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4558.

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Endoscopic OCT utilizes a special miniature probe in the sample arm to access tubular organs inside the human body, such as the cardiovascular system, the lung, the gastrointestinal tract, the urinary tract, and the breast duct. We present an optical design of a dynamic focus endoscopic probe that is capable of about 4 to 6 micrometers] lateral resolution over a large working distance (i.e. up to 5 mm from the distal end of the probe). The dynamic focus capability allows integration of the endoscopic probe to GD-OCM imaging to achieve high resolution endoscopic tomograms. We envision the futur
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17

Bachmann, Adrian H. "Phase-locked Fourier domain optical coherence tomography /." Lausanne : EPFL, 2007. http://library.epfl.ch/theses/?nr=3847.

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Thèse Ecole polytechnique fédérale de Lausanne EPFL, no 3847 (2007), Faculté des sciences et techniques de l'ingénieur STI, Programme doctoral Photonique, Institut d'imagerie et optique appliquée IOA (Laboratoire d'optique biomédicale LOB). Dir.: Theo Lasser, Rainer Leitgeb.
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18

Jiao, Shuliang. "Polarization-sensitive Mueller-matrix optical coherence tomography." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/398.

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Measuring the Mueller matrix with optical coherence tomography (OCT) makes it possible to acquire the complete polarization properties of scattering media with three-dimensional spatial resolution. We first proved that the measured degree-of-polarization (DOP) of the backscattered light by OCT remains unity-a conclusion that validated the use of Jones calculus in OCT. A multi-channel Mueller-matrix OCT system was then built to measure the Jones-matrix, which can be transformed into a Mueller matrix, images of scattering biological tissues accurately with single depth scan. We showed that when
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19

Kirillin, M. (Mikhail). "Optical coherence tomography of strongly scattering media." Doctoral thesis, University of Oulu, 2008. http://urn.fi/urn:isbn:9789514287572.

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Abstract Optical coherence tomography (OCT) is a modern rapidly developing technique for non-invasive imaging of the internal structure of optically non-uniform objects based on the principles of low-coherent interferometry. However, multiple scattering of light in the objects under study brings distortions to the images obtained by OCT. The analysis of formation of the OCT signals is required for understanding the role of multiple scattering in this formation and providing recommendations for optimal configuration of a measuring setup. In the present thesis formation of the OCT signals and im
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20

Meer, Freek Jeroen van der. "Vascular applications of quantitative optical coherence tomography." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2005. http://dare.uva.nl/document/89109.

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21

Fergusson, James. "Full field swept source optical coherence tomography." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/49959/.

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Optical Coherence Tomography (OCT) is a non-invasive volumetric imaging technique that offers micron scale resolution over several millimetres of depth penetration in tissue. The aim of the project was to develop Full Field Swept Source OCT (FFSSOCT), charting the specifications of the system throughout and drawing comparisons with available Fourier domain OCT (FDOCT) systems. A super luminescent diode (SLD) light source was tuned to different optical frequencies using an acousto-optical tunable filter. The successive optical frequencies were distributed across the sample in parallel and the s
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22

Byers, Robert. "Clinical applications of angiographic optical coherence tomography." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/21904/.

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Angiographic optical coherence tomography (OCTA) has rapidly found utility within many facets of medical research. Here OCTA algorithms are enabled on a commercial OCT system and verified through correlation with intra-vital light microscopy (IVM). While the vast majority of vessels were accurately measured, smaller vessels (< 30μm) have a tendency to appear dilated in comparison to IVM. The technique was also expanded upon to facilitate the imaging of subcutaneous murine fibrosarcoma tumours, negating the requirement for an intra-vital window. It was found that vessel measurement sensitivity
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23

Tung, Kai-Pin. "Coronary segmentation in intravascular optical coherence tomography." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/24126.

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Cardiovascular disease (CVD) is a fatal disease of the heart or blood vessels. The greatest number of deaths from CVD is coronary heart disease (CHD). It is characterised by thickening of the arterial vessel wall due to atheromatous plaque which may result in narrowing or even occlusion of arterial lumen. Currently, intravascular optical coherence tomography (IVOCT) has been increasingly used in the clinic for the diagnosis of CHD because it permits high-resolution direct tomographic visualisation of cross-sectional images. With IVOCT techniques, stenosis and restenosis caused by plaques and n
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24

Arthur, Donna Louise. "Doppler optical coherence tomography for microcirculation studies." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/doppler-optical-coherence-tomography-for-microcirculation-studies(a18d59c3-6cfb-4266-98b1-188040bc120f).html.

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This thesis forms part of an ongoing long-term project to investigate the suitability of Doppler optical coherence tomography (OCT) as a measurement tool to investigate skin thickness and blood flow in patients with systemic sclerosis. There is a discussion of the characterisation of an electro-optic phase modulator for use in a Doppler OCT imaging system which is being built for the purpose of clinical studies. In addition to this the development of software for the same system is described. The work includes a comparison of two methods of obtaining Doppler information that were tested with t
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25

Chang, Whan Wook. "Functional optical coherence tomography for clinical otolaryngology." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12730.

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Thesis (Ph.D.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Cross-sectional imaging of rapidly vibrating tissues or biomaterials under rapid periodic motion is useful for medical diagnosis and tissue engineering. Optical coheret:tce tomography (OCT) is a powerful techni
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26

Fleming, Christine P. "Characterization of Cardiac Tissue Using Optical Coherence Tomography." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1270718628.

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27

Faber, Dirk Johannes. "Functional optical coherence tomography spatially resolved measurements of optical properties /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2005. http://dare.uva.nl/document/88794.

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28

Toadere, Florin. "Dispersion in optical configurations and sources for Optical Coherence Tomography." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/64278/.

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Optical coherence tomography is a biomedical imaging technique employed to visualize tissue structure, ocular vasculature and blood flow. An OCT system is a non-invasive biomedical imaging system that provides bi-dimensional and three-dimensional images of biological tissue with micrometer scale resolution and millimeter scale depth range. In clinical application, OCT is employed in vivo imaging of the human eye. Swept source optical coherence tomography (SS-OCT) is the latest and fastest method of scanning. However, there are several disadvantages of the SS-OCT such as: the decrease of the ro
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29

Siddiqui, Meena. "Optical domain subsampling for data-efficient optical coherence tomography (OCT)." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/82390.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 97-100).<br>Recent advances in optical coherence tomography (OCT) have led to higher-speed sources that support imaging over longer depth ranges. Limitations in the bandwidth of state-of-the-art acquisition electronics, however, prevent adoption of these advances into clinical applications. This thesis introduces optical-domain subsampling as a method for increasing the imaging range while reducing
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30

Tearney, Guillermo J. "Optical biopsy of in vivo tissue using optical coherence tomography." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/10139.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.<br>Includes bibliographical references (leaves 213-220).<br>by Guillermo James Tearney.<br>Ph.D.
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31

Armstrong, Julian. "Anatomical optical coherence tomography in the human upper airway /." Connect to this title, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0022.

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32

Tuten, William Scott. "Anterior Segment Optical Coherence Tomography-Based Phakometry Measurements in Children." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243629782.

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33

Zhang, Yaokun [Verfasser]. "Optical Coherence Tomography guided Laser-Cochleostomy / Yaokun Zhang." Karlsruhe : KIT Scientific Publishing, 2015. http://www.ksp.kit.edu.

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34

Casaubieilh, P. "Fibre optic fizeau intererometer for optical coherence tomography." Thesis, Cranfield University, 2006. http://dspace.lib.cranfield.ac.uk/handle/1826/5664.

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The aim of the project was to develop the Fizeau interferometer configuration to take advantage of the benefits derived from its “downlead insensitivity” to temperature and polarisation fading. This sensing interferometer was investigated and implemented in conjunction with various processing interferometers with the view to achieve optimised performances for Optical Coherence Tomography (OCT) application. A comprehensive theoretical analysis has been carried for Signal-to-Noise ratio of these OCT systems. Balanced detection indenting two detectors with anti-phase signals was also investigated
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35

Song, Shaozhen. "Shear wave elastography based on optical coherence tomography." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/9cbb776c-35c1-4b5c-9fca-f00a8b603bd6.

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Mechanical properties of biological tissue are involved in a wide range of modern advances of medical science and technology. The mechanical property of biological tissue is directly related to the functionalities of tissue or organ, hence the in-depth knowledge of tissue mechanical property could lead to many benefits in medical research and health care. In clinical practice, accurate estimation of tissue mechanical property may facilitate to predict any possible pathological alterations, or to propose artificial intervention approaches. With the purpose of a quantitative, directly visualized
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36

Chau, Alexandra H. (Alexandra Hung) 1980. "Elastography of coronary vessels using optical coherence tomography." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/29943.

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37

Jenkins, Michael W. "Imaging the Embryonic Heart with Optical Coherence Tomography." Case Western Reserve University School of Graduate Studies / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1207340565.

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38

Ducros, Mathieu Gilles. "Polarization sensitive optical coherence tomography of the eye /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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39

Fujimoto, Masahiro. "Lacrimal Canaliculus Imaging Using Optical Coherence Tomography Dacryography." Kyoto University, 2019. http://hdl.handle.net/2433/242892.

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Wang, Hui. "ULTRA HIGH RESOLUTION AND CONTRAST SENSITIVE OPTICAL COHERENCE TOMOGRAPHY." Case Western Reserve University School of Graduate Studies / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1207178563.

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41

Peric, Borislava. "Optical coherence tomography applied to investigations of optical properties of paintings." Thesis, Nottingham Trent University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510265.

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42

Adie, Steven G. "Enhancement of contrast in optical coherence tomography : new modes, methods and technology." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0127.

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This thesis is concerned with exploiting the native optical coherence tomography (OCT) contrast mechanism in new ways and with a new contrast mechanism, in both cases to enhance the information content of the tomographic image. Through experiments in microsphere solutions, we show that static speckle contains information about local particle density when the effective number of scatterers in the OCT resolution volume is less than about five. This potentially provides contrast enhancement in OCT images based on local scatterer density, and we discuss the experimental conditions suited to utilis
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43

Chan, Chun-wang Aaron, and 陳俊弘. "Statistical estimation of haemodynamic parameters in optical coherence tomography." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206460.

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Optical coherence tomography (OCT) is an imaging modality analogous to ultrasound. By using the interference properties of light, one may image to micrometer resolutions using interferometric methods. Most modern systems can acquire A-scans at kHz to MHz speeds, and are capable of real-time 3D imaging. OCT has been used extensively in ophthalmology and has been used in angiography to quantify blood flow. The aim of this research has been to develop statistically optimal estimators for blood flow estimation to take advantage of these hardware advances. This is achieved through a deeper understa
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Xu, Jianbing, and 徐鉴冰. "Optical coherence tomography : from system design to spectroscopic applications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206473.

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Optical coherence tomography (OCT), as a newly developed imaging modality, has attracted significant attention due to its capability to obtain the cross-sectional information of biological tissues in a non-invasive way, with resolution in the range of several micrometers. The third-generation swept source OCT (SS-OCT), is superior in the speed, imaging range and signal-to-noise ratio (SNR) compared with the previous time-domain OCT (TD-OCT) and spectral domain OCT (SD-OCT), and therefore forms our research focus. In this thesis, for the first time, I investigate the deployment of Fourier do
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Dubosson, Fabrice. "Optical coherence tomography : 3-D dental scanning imaging probe /." Sion, 2007. http://doc.rero.ch/search.py?recid=8351&ln=fr.

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Lauri, J. (Janne). "Doppler optical coherence tomography in determination of suspension viscosity." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526202068.

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Abstract Doppler optical coherence tomography (DOCT) provides a non-disruptive, high resolution and real-time method for imaging flow velocity profiles inside small channels and capillaries. DOCT has been mostly used in the biomedical field to image blood flow. However, applications in the field of rheology have been rare. In this thesis, the time domain DOCT (TD-DOCT) was utilized to measure flow velocity profiles inside capillaries with high resolution. Time domain configuration was chosen due to the ability to implement dynamic focusing and, in addition, to have sufficient velocity range, e
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Zhou, Xin. "Polarization-sensitive optical coherence tomography imaging of articular cartilage." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62761.

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Articular cartilage is the connective tissue protecting the joints, which can be divided into four structural zones from shallow to deep: superficial zone, transitional zone, deep zone and calcified zone. Osteoarthritis, a common joint disease, is associated with the progressive degeneration of the cartilage structure. The destruction progressively develops from the superficial zone towards the deep zone as the disease progresses. Thus, visualization of articular cartilage structural zones would significantly facilitate cartilage disease diagnosis, repair, regeneration, and transplantation. P
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Woods, Daniel. "Selection in depth in Fourier domain optical coherence tomography." Thesis, University of Kent, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498894.

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Greenwood, Purnima. "Advanced quatum dot superluminescent diodes for optical coherence tomography." Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548378.

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Wang, Jingyu. "Optical coherence tomography methods using 2-D detector arrays." Thesis, University of Kent, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.650808.

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Optical coherence tomography (OCT) is a non-invasive, non-contact optical technique that allows cross-section imaging of biological tissues with high spatial resolution, high sensitivity and high dynamic range. Standard OCT uses a focused beam to illuminate a point on the target and detects the signal using a single photodetector. To acquire transverse information, transversal scanning of the illumination point is required. Alternatively, multiple OCT channels can be operated in parallel simultaneously; parallel OCT signals are recorded by a two-dimensional (2D) detector array. This approach i
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