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Dissertations / Theses on the topic 'Optical mouse'

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1

Tona, Yosuke. "In Vivo Imaging of Mouse Cochlea by Optical Coherence Tomography." Kyoto University, 2016. http://hdl.handle.net/2433/215400.

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Final publication is available at http://journals.lww.com/otology-neurotology/Pages/default.aspx<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(医学)<br>甲第19574号<br>医博第4081号<br>新制||医||1013(附属図書館)<br>32610<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 渡邉 大, 教授 伊佐 正, 教授 一山 智<br>学位規則第4条第1項該当
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Tumlinson, Alexandre Rex. "Ultrahigh-Resolution Endoscopic Optical Coherence Tomography for In Vivo Mouse Colonoscopy." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/194990.

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In vivo monitoring of mouse models of colon cancer promises to reduce the cost of research by improving sacrifice timing and allowing serial studies that observe the progression of disease and drug efficacy in a relatively small set of animals. Optical coherence tomography (OCT) is an optical analog of ultrasound imaging, capable of minimally-invasive mapping of light scatter intensity up to 2 mm deep in tissue. In this work, factors limiting resolution in OCT were examined and devices were created and applied to mouse colon imaging that extended the state-of-the-art in endoscopic ultrahigh-re
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3

Marques-Smith, Andre. "Using optical stimulation to study the developing thalamocortical circuit in mouse somatosensory cortex." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:43004cd7-a391-4e55-aa66-dced1212574d.

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4

Kocaoglu, Omer Pars. "Development of an In Vivo Fundus Imaging and Retinal Optical Coherence Tomography System for the Mouse." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/482.

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The purpose of this project is to develop a retinal imaging system suitable for routine examination or screening of mouse models that acquires fundus and Optical Coherence Tomography (OCT) images. The imaging system is composed of a digital camera with an objective for biomicroscopic examination of the fundus, an OCT interferometer, an OCT beam delivery system designed for the mouse eye, and a mouse positioning stage. The image acquisition is controlled with software that displays the fundus and OCT images in real-time, and allows the user to control the position of the OCT beam spot on the fu
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Schnabel, Christian, Anett Jannasch, Saskia Faak, Thomas Waldow, and Edmund Koch. "4D optical coherence tomography of aortic valve dynamics in a murine mouse model ex vivo." SPIE, 2015. https://tud.qucosa.de/id/qucosa%3A35044.

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The heart and its mechanical components, especially the heart valves and leaflets, are under enormous strain during lifetime. Like all highly stressed materials, also these biological components undergo fatigue and signs of wear, which impinge upon cardiac output and in the end on health and living comfort of affected patients. Thereby pathophysiological changes of the aortic valve leading to calcific aortic valve stenosis (AVS) as most frequent heart valve disease in humans are of particular interest. The knowledge about changes of the dynamic behavior during the course of this disease and th
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Giardini, Francesco. "Morpho-functional investigation of cardiac remodeling in an arrhythmogenic mouse model by advanced optical methods." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1211015.

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Severe remodeling processes may occur in the heart due to both genetic and non-genetic diseases. Structural remodeling, such as collagen deposition (fibrosis) and cellular misalignment, can affect electrical conduction at different orders of magnitude and, eventually, lead to arrhythmias. In this scenario, arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease that involves ventricular dysfunction, arrhythmias, and localized replacement of contractile fibers with fibrofatty scar tissue. Unfortunately, nowadays, redicting the impact of fine structural alterations on the electrical d
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7

Hariri, Lida Pamela. "Evaluation of Mouse Models of Colorectal Cancer Using Optical Coherence Tomography and Laser Induced Fluorescence Spectroscopy." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/195984.

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Colorectal cancer (CRC) is the third leading cause of cancer related deaths. Rodent models of CRC are useful for evaluating diagnostic tools, therapeutics, and disease progression; however, an appropriate imaging tool is needed. Optical coherence tomography (OCT) is a non-destructive imaging modality readily packaged into small diameter endoscopes. Using a near- infrared light source, structural images are generated from index of refraction mismatches with resolutions of 2-15 mm at imaging depths of up to 1.3 mm. In contrast, laser-induced fluorescence (LIF) spectroscopy provides informati
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LeGendre-McGhee, Susan. "Evaluating Chemopreventive and Chemotherapeutic Agent Effectiveness in a Mouse Model of Sporadic Colorectal Cancer Using Optical Coherence Tomography." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/228440.

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Optical coherence tomography (OCT) is a minimally-invasive imaging modality that generates high resolution cross-sectional images of tissue. The present study employed a 2 mm diameter endoscopic spectral domain OCT system in the in vivo evaluation of the drugs α-Difluoromethylornithine and Sulindac as chemopreventive and chemotherapeutic agents in a mouse model of sporadic colorectal cancer. 30 mm lateral images of each colon at eight different rotations were obtained at five different time points. Visual analysis of the images was performed to determine the number and size of discrete adenoma
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9

Wall, Richard Andrew. "Multi-Modality Endoscopic Imaging for the Detection of Colorectal Cancer." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/301761.

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Optical coherence tomography (OCT) is an imaging method that is considered the optical analog to ultrasound, using the technique of optical interferometry to construct two-dimensional depth-resolved images of tissue microstructure. With a resolution on the order of 10 μm and a penetration depth of 1-2 mm in highly scattering tissue, fiber optics-coupled OCT is an ideal modality for the inspection of the mouse colon with its miniaturization capabilities. In the present study, the complementary modalities laser-induced fluorescence (LIF), which offers information on the biochemical makeup of the
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10

RITELLI, Rossana. "Generating a pancreatic cancer mouse model: from Cancer Stem Cells to in vivo imaging strategies." Doctoral thesis, Università degli Studi di Verona, 2010. http://hdl.handle.net/11562/344615.

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Presupposti: nonostante gli enormi sforzi della ricerca per lo studio del carcinoma del pancreas, a tutt’oggi questo tumore aggressivo rimane incurabile e necessita di terapie mirate che garantiscano un miglioramento concreto della qualità della vita dei pazienti. Pertanto, è forte il bisogno di creare un sistema efficace e mirato all’identificazione di nuovi composti per la cura del cancro del pancreas. Scopo: lo scopo di questo lavoro è quello di contribuire alla generazione di un sistema che porti selezione di nuovi composti per il trattamento del carcinoma pancreatico. Questo sistema
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Watson, Jennifer Marie. "Examination of Diagnostic Features in Multiphoton Microscopy and Optical Coherence Tomography Images of Ovarian Tumorigenesis in a Mouse Model." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/293473.

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Ovarian cancer is a deadly disease owing to the non-specific symptoms and suspected rapid progression, leading to frequent late stage detection and poor prognosis. Medical imaging methods such as CT, MRI and ultrasound as well as serum testing for cancer markers have had extremely poor performance for early disease detection. Due to the poor performance of available screening methods, and the impracticality and ineffectiveness of taking tissue biopsies from the ovary, women at high risk for developing ovarian cancer are often advised to undergo prophylactic salpingo-oophorectomy. This surgery
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Chou, Tsung-Han. "Age-Related Structural and Functional Changes of the Mouse Eye: Role of Intraocular Pressure and Genotype." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/532.

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The murine eye naturally undergoes post-natal changes in eye size. This dissertation quantifies longitudinal structural and functional changes in control mice (C57BL/6J (B6), D2-Gpnmb+/SjJ) and in DBA/2J (D2) mice, which spontaneously develop elevated intraocular pressure (IOP). IOP elevation results in abnormal eye elongation, retinal nerve fiber layer (RNFL) thickness thinning and retinal ganglion cell (RGC) dysfunction and demise resembling human glaucoma. I measured structural changes with Optical Coherence Tomography (OCT), and RGC function with Pattern Electroretinogram (PERG). I also de
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Soleimanzad, Haleh. "Development and application of quantitative imaging to study cerebral blood flow in a mouse model of obesity." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS604.

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Selon l’organisation mondiale de la santé, dans les pays en développement, la proportion de personnes obèses a presque triplé depuis 1980 et presque doublé dans les pays à revenu élevé. Parmi ces statistiques, en France, 16,8% des hommes et 17,4% des femmes sont obèses. Les taux mondiaux d'obésité devraient monter au cours de la prochaine décennie pour atteindre un cinquième des adultes en 2025. L'obésité est due à de multiples facteurs, dont la consommation excessive d’aliments riches en gras et en sucres, ainsi que des facteurs génétiques, psychosociaux et environnementaux. L'incidence de ma
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SEGALA, AGNESE. "Multidimensional approach to Frailty Syndrome of the elderly: preclinical study in a mouse model and set up of a novel optical diagnostic technique in humans." Doctoral thesis, Università degli studi di Brescia, 2021. http://hdl.handle.net/11379/550296.

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Multidimensional approach to Frailty Syndrome of the elderly: preclinical study in a mouse model and set up of a novel optical diagnostic technique in humans<br>Multidimensional approach to Frailty Syndrome of the elderly: preclinical study in a mouse model and set up of a novel optical diagnostic technique in humans
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15

Mehta, Alok Ajay. "Micro-Optic-Spectral-Spatial-Elements (MOSSE)." Doctoral diss., University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3481.

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Over a wide range of applications, optical systems have utilized conventional optics in order to provide the ability to engineer the properties of incident infra-red fields in terms of the transmitted field spectral, spatial, amplitude, phase, and polarization characteristics. These micro/nano-optical elements that provide specific optical functionality can be categorized into subcategories of refractive, diffractive, multi-layer thin film dichroics, 3-D photonic crystals, and polarization gratings. The feasibility of fabrication, functionality, and level of integration which these elements ca
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16

Hübner, Doreen, Christiane Rieger, Ralf Bergmann, et al. "An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-231536.

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Background Novel theranostic options for high-risk non-muscle invasive bladder cancer are urgently needed. This requires a thorough evaluation of experimental approaches in animal models best possibly reflecting human disease before entering clinical studies. Although several bladder cancer xenograft models were used in the literature, the establishment of an orthotopic bladder cancer model in mice remains challenging. Methods Luciferase-transduced UM-UC-3LUCK1 bladder cancer cells were instilled transurethrally via 24G permanent venous catheters into athymic NMRI and BALB/c nude mice as well
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Jorge, Ana Elisa Serafim. "Terapia fotodinâmica em pele fotoenvelhecida de camundongo hairless: avaliação por técnicas óptica e histopatológica." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-07072014-142307/.

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A exposição crônica à radiação ultravioleta (UV) resulta no fotoenvelhecimento da pele humana. A fim de tratá-lo, a terapia fotodinâmica (TFD) - técnica que utiliza luz, um fotossensibilizador (FS) e oxigênio molecular - tem sido utilizada em ambientes clínicos, no entanto são escassas as investigações que revelam os achados histopatológicos desse tratamento na pele fotoenvelhecida. Com isso, o objetivo deste trabalho foi analisar experimentalmente os efeitos da TFD na pele fotoenvelhecida de camundongos por meio de técnicas ópticas e histológicas. Portanto, foram utilizados camundongos hairle
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18

Hübner, Doreen, Christiane Rieger, Ralf Bergmann, et al. "An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment." BioMed Central, 2017. https://tud.qucosa.de/id/qucosa%3A30688.

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Background Novel theranostic options for high-risk non-muscle invasive bladder cancer are urgently needed. This requires a thorough evaluation of experimental approaches in animal models best possibly reflecting human disease before entering clinical studies. Although several bladder cancer xenograft models were used in the literature, the establishment of an orthotopic bladder cancer model in mice remains challenging. Methods Luciferase-transduced UM-UC-3LUCK1 bladder cancer cells were instilled transurethrally via 24G permanent venous catheters into athymic NMRI and BALB/c nude mice as well
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19

Zhang, Xu. "Stimulated Raman Scattering Imaging of Biomolecules and Single Cell Transcriptome Analysis of Mouse Retina." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467491.

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Complex information within biological systems is being uncovered at an unprecedented speed thanks to the rapid technical development of a wide variety of research tools, among which imaging and sequencing technologies are attracting big attention in recent years. Optical imaging enables the visualization of the spatial distribution of biomolecules at cellular level, allowing deeper understanding of the structure and dynamics of biological systems. Fluorescence microscopy has contributed greatly to our understanding of these processes, but it relies on the use of fluorescent labels or dyes. The
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20

Zhao, Menghua. "Mouillage sur gels mous." Electronic Thesis or Diss., Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLET024.

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Dans cette thèse, nous nous sommes intéressés à la statique et la dynamique du mouillage de gouttes d’eau sur des substrats mous tels que des gels, encore connu sous le nom d’élastomouillage. Pour ce faire, nous avons d'abord développé une méthode quantitative de visualisation par strioscopie permettant de mesurer la déformation de la surface d'un film de gel transparent avec une précision élevée. Nous montrons que la déformation superficielle de films mous de silicone (PDMS) dépend de la taille des gouttelettes déposées ainsi que de l'épaisseur et de l’élasticité de ces films. Nous avons cons
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Zhao, Menghua. "Mouillage sur gels mous." Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLET024/document.

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Dans cette thèse, nous nous sommes intéressés à la statique et la dynamique du mouillage de gouttes d’eau sur des substrats mous tels que des gels, encore connu sous le nom d’élastomouillage. Pour ce faire, nous avons d'abord développé une méthode quantitative de visualisation par strioscopie permettant de mesurer la déformation de la surface d'un film de gel transparent avec une précision élevée. Nous montrons que la déformation superficielle de films mous de silicone (PDMS) dépend de la taille des gouttelettes déposées ainsi que de l'épaisseur et de l’élasticité de ces films. Nous avons cons
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Robert, Benjamin. "Etude des Propriétés Viscoélastiques des Tissus Mous par Elastographie IRM. Une Approche Multi-Echelle." Phd thesis, Université Paris-Diderot - Paris VII, 2009. http://pastel.archives-ouvertes.fr/pastel-00556732.

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Ces dernières années, l'élastographie ultrasonore et IRM s'est développée afin de caractériser les propriétés viscoélastiques des tissus mous. Ces nouvelles méthodes d'imagerie sont particulièrement prometteuses pour caractériser des pathologies comme les carcinomes dans le sein qui présentent une élasticité plus importante que les tissus environnants. Dans la première partie du manuscrit, une présentation des milieux viscoélastiques permet de décrire les comportements mécaniques observés lorsqu'un tel milieu est sollicité par une onde élastique. Différents modèles de propagation d'ondes de ci
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Capito, Ruiz Linda J. "Optical Flow-based Artificial Potential Field Generation for Gradient Tracking Sliding Mode Control for Autonomous Vehicle Navigation." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555599397128602.

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Daoudi, Khalid. "Caractérisation des milieux mous par optoélastographie transitoire." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2009. http://pastel.archives-ouvertes.fr/pastel-00548741.

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Au cours de ce travail, nous avons étudié une méthode de caractérisation des milieux mous combinant ondes optiques et mécaniques. Cette méthode s'appuie sur une détection optique d'un mouvement transitoire causé par la force de radiation acoustique, induit en profondeur de milieux mous optiquement diffusants. Le mouvement consiste en un déplacement initialement au foyer acoustique qui se propage par la suite dans le milieu sous forme d'ondes de cisaillement. Le principe de la détection est basé sur l'illumination du milieu avec une lumière cohérente. La lumière traverse le milieu en étant fort
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Zerrari, Naoual. "Caractérisation des tissus biologiques mous par diffusion multiple de la lumière." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10052/document.

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La diffusion multiple de la lumière(DWS) est une technique qui permet de sonder la dynamique interne de milieux opaques et concentrés à des fréquences élevées. Elle a été utilisée pour déterminer les propriétés viscoélastiques de ces milieux. Elle a l'avantage d'être non destructive, rapide et sensible. Ce travail a pour objectif l'étude des tissus biologiques mous par DWS. La première étape est la mise en place du dispositif expérimental. Afin d'évaluer les limites de la technique, des études successives ont été réalisées sur des matériaux de complexité croissante (une suspension, le lait et
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Cellier, Laura. "Rôle de la dynamique mitochondriale à la phase aiguͭe de l'infarctus du myocarde Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model Remote ischemic conditioning influences mitochondrial dynamics." Thesis, Angers, 2017. http://www.theses.fr/2017ANGE0085.

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L’infarctus du myocarde (IDM) est une pathologie décrite comme étant "la mort des cellules myocardiques après une ischémie prolongée". Actuellement, la reperfusion est la stratégie la plus efficace pour limiter l’étendue de cette nécrose myocardique et améliorer le pronostic des patients. Cependant, cette reperfusion entraine des lésions secondaires irréversibles que l’on appelle lésions de reperfusion. Pour protéger le coeur de ces lésions de reperfusion, des stratégies sont à l’étude avec notamment la cardioprotection par le conditionnement ischémique à distance. Ce conditionnement consiste
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Waris, Marc. "Mise en œuvre, instrumentation, validation et modélisation d’un système d’injection RTM pour la fabrication de structures composites de hautes performances." Thesis, Saint-Etienne, EMSE, 2012. http://www.theses.fr/2012EMSE0661/document.

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Les matériaux composites ont connu ces dernières années une forte croissance, croissance aujourd'hui renforcée par les nouvelles normes européenne visant à diminuer les émissions CO2 d'ici 2020. La réalisation de pièces complexes peut poser de nombreuses problématiques de fabrication comme la formation de zones sèches, ou la création de distorsions géométriques. Les origines de ces problématiques sont souvent liées à un manque de connaissance et de maîtrise des phases d'imprégnation des renforts et de cuisson du matériau. L'amélioration de la robustesse des procédés nécessite d'avoir une conna
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Bonezzi, Paul J. "The development of outer retinal photoresponsivity and the effects of sensory deprivation." University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1602525875711526.

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Tsai, Chien-Wen, and 蔡建文. "optical mouse lens design." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/88920213033929924074.

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Tseng, Jin-Shing, and 曾進興. "Design of Pen-Type Optical Mouse." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/60729185754851776118.

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碩士<br>國立交通大學<br>光電工程學系<br>100<br>The pen-type optical mouse is an innovative mouse design which based on the principle of original optical imaging theory but it reduces the volume of mechanism much smaller to be pen-shape. In the thesis, it presents the design of “co-axial” illumination device to improve the size problem and to arise the MTF performance of imaging lens in the meantime. Besides, taking the problems of economizing power and cost into consideration, this thesis uses the SMD LED (Surface-mount device Light-emitting diode) for its smaller size, lower power loss, and besides, the co
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Lin, Yu-Chen, and 林祐震. "Integrated Package on Optical Device of Laser Mouse." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/18815877371433511329.

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碩士<br>中原大學<br>電子工程研究所<br>104<br>In this paper, we have successfully demonstrated a simple process flow and a high performance laser mouse by using integrated package of sensors, laser and lenses. The properties of interface functions, power consumption and the light stripe image were investigated on three types of typical optical, three-piece and integrated package. The test of interface function used sliding test on manual and mechanical mode to compare ability, positioning and accuracy under different operating speeds on different desktop. The results show that the characteristics of integra
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Tien, C. M., and 田昌明. "Vessel Segmentation of Mouse Skin Image Using Optical Coherence Tomography." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/46663667703966636913.

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Chang, Kai-Yao, and 張凱堯. "Laser Scanning Optical Resolution Photoacoustic Transcranial Microscopy of Mouse Brains." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/z5p3r8.

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Chang, Yen-Chan, and 張晏展. "Direct Observation of Mouse RAD51 Assembly Unit Using Optical Tweezers." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/8tz9dj.

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碩士<br>國立臺灣大學<br>化學研究所<br>107<br>Recombinases are shown to form closed-ring (hexameric to octameric) structure in electron microscopic studies, but direct structural evidence in solution is missing. We used the passive force-clamp optical tweezers to directly observe the existence of oligomeric recombinase nucleoprotein filament assembly in real-time. To achieve sufficient resolution to resolve individual steps during filament assembly, several instrumental improvements and programming developments have been achieved: (1) improved our home-built optical tweezers stability by using a circuit-bas
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Yang, Kuo-Chung, and 楊國忠. "THE ANALYSIS AND DESIGN OF CMOS RETINAL CHIPS FOR OPTICAL MOUSE APPLICATION." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/83445548928476074547.

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碩士<br>國立交通大學<br>電子工程系所<br>97<br>In this thesis, CMOS retinal chips for optical mouse application are proposed. The CMOS retinal chips are designed to replace the conventional image sensor integrated with an analog-to-digital converter (ADC) for optical mouse application, the ADC can be eliminated from the conventional optical mouse, which greatly reduces the complexity of the design. The retinal chips III with smoothing networks are adopted to achieve simple architecture, low power dissipation, and low cost. The retinal chips contains focal plane sensory arrays of 32x32 pixels, address decoder
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Walls, Johnathon R. "Improving optical projection tomography for three-dimensional imaging of the embryonic mouse." 2008. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=742599&T=F.

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Yu, Tzung-Shiun, and 郁宗勳. "Optical clearing of mouse gastric tissues for microtome-free, 3D confocal microscopy." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/62460386152285402121.

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Martins, Ana Francisca Madeira. "Mouse versus Human skin: comparing human and mouse skin when applying MicronJet® 600 injections." Master's thesis, 2017. http://hdl.handle.net/10451/35942.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017<br>Microneedles are an emerging technology in clinical practice, being used as an alternative for the administration of drug and other bioactive substances, such as pDNA, through the human skin, aiming to achieve both the topical and the systemic effects. Once it is very difficult to obtain human skin, animal models have been widely used to mimic the physiological and pathological skin conditions in Humans. However, structural and physiological differences between these tissues com
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Chu, Chi-Chun, and 朱濟群. "A Study of Measurement of Tracking Performance Characteristics of Optical Mouse Motion Sensor." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/52314268970555606967.

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碩士<br>國立交通大學<br>電機資訊學院碩士在職專班<br>92<br><Mouse>:Mouse is one of the most important input devices in personal computer peripheral now. Mouse’s ability also determines the performance for the computer operation. However; Resolution and Accuracy are major factors to impact the cursor working smooth of the mouse. Thus the Motion Sensor’s characteristic decides the Resolution and Accuracy of the tracking performance. this thesis is focused on the motion sensor of the optical mouse and study in different light source (wavelength;λ); height; angle and velocity to test tracking performance. In order to
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Nattar, Ranganath Gayathri. "Signal propagation in recurrent networks of mouse barrel cortex." Thesis, 2011. http://hdl.handle.net/2152/ETD-UT-2011-12-4577.

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Sensory signals are represented and propagated as spiking activity in multiple neuronal populations to lead to cognitive or motor behavior in organisms. Neural processing underlying sensory-motor behavior is understood by uncovering the governing computational principles and the biophysical mechanisms that implement the principles. While these mechanisms have been studied extensively at the single-neuron and system levels, activity within neuronal networks significantly impact neural processing. For example, there are spatiotemporal interactions (neural correlations) between responses of neuro
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Lin, Yu-Hsuan, and 林宇軒. "Investigating How Mouse RAD51 Filament Dynamics Regulated by SWI5-SFR1 Complex Using Optical Tweezers." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/8s9wx8.

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碩士<br>國立臺灣大學<br>化學研究所<br>105<br>Homologous recombination catalyzed by RAD51 recombinases is a crucial DNA repair pathway in eukaryotes. In the presence of ATP, RAD51 assembles on single-stranded DNA to form nucleoprotein filaments, and initiates homologous recombinational repair of DNA double-stranded breaks. The SWI5-SFR1 complex has been found to regulate RAD51 filament assembly and enhance strand exchange activity, but the detailed mechanism is not clear. Here we improved our home-built optical tweezers platform to 1 nm resolution, and utilized it to study the assembly and disassembly dynam
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Jiang, Ming-Long, and 江明龍. "APPLICATION OF AHP TO EVALUATE NEW PRODUCT DEVELOPMENT PROJECTS - A CASE STUDY OF OPTICAL MOUSE." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/6a3zj6.

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碩士<br>大同大學<br>工程管理碩士在職專班<br>102<br>The computer optical mouse is combination of electronic, optical, and mechanical technologies that has been widely used as an input device for over two decades. Taiwanese manufacturers have gained leading positions in the supply of key components and the OEM production of these devices. Accurate assessments of the demand for new products could help optical mouse manufacturers to adjust their use of resources and thereby enhance their competitiveness in the industry. This study employed the analytic hierarchy process (AHP) in conjunction with expert questionna
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Hadrabová, Jana. "Vývoj experimentálního modelu pro testování žloutkových protilátek jako prostředku profylaxe bakteriálních infekcí." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-342930.

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Respiratory system of the cystic fibrosis patients is affected by the defect in gene coding for protein transporter for chloride ions - CFTR ("Cystic fibrosis transmembrane conductance regulator"). The main complication of this disease is airways chronic inflammation, in particular caused by bacterium Pseudomonas aeruginosa. Due to asialylation of the lung surfaces the bacterial adhesion is facilitated, for example via lectin PAIIL. The ability of the chicken yolk antibodies to protect lung epithelial cells against Pseudomonas aeruginosa adhesion has been already proven. Therefore this thesis
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Creutzfeldt, Claire [Verfasser]. "The role of ephrinA for retinotopic map formation in mouse visual cortex : an optical imaging study / vorgelegt von Claire Creutzfeldt." 2003. http://d-nb.info/970271832/34.

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Guy, Julien. "Order under the guise of chaos: functional neuroanatomy of the somatosensory "barrel" cortex of the reeler mutant mouse." Doctoral thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-0028-8752-9.

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Pocock, Ginger Madeleine. "High resolution retinal imaging to evaluate laser and light safety in the retina for near and long term health effects." Thesis, 2012. http://hdl.handle.net/2152/ETD-UT-2012-12-6830.

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The purpose of this research was to investigate detect and monitor laser-tissue interactions at threshold and potentially sub-threshold levels of injury. High resolution imaging modalities can provide a deeper understanding of candidate biomarkers disease and injury at the molecular, cellular, and tissue-levels which can be used to identify and diagnose early stages disease and damage. In addition, multi-scale and multi-modal imaging have also been used to identify inherent biomarkers of retinal disease and injury. Monitoring tissue changes can be mapped back to biological changes at the cellu
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Lai, Pei-Yu, and 賴沛妤. "Multi-functional optical coherence tomography for the in vivo longitudinal tracking of lymphangiography and angiography in a cutaneous melanoma mouse model." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/hy7df7.

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Stodieck, Sophia Katharina. "The role of postsynaptic density (PSD) proteins PSD-95 and PSD-93 for mouse visual cortical plasticity and vision." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0023-3F15-A.

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Brais-Brunet, Simon. "Instrumentation et méthodes d’analyse appliquées à l’évaluation du développement rétinien chez le souriceau par tomographie par cohérence optique." Thesis, 2019. http://hdl.handle.net/1866/24516.

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Ce mémoire par article décrit le développement d’instrumentation optique et d’algorithmes qui ont servi à l’étude du développement rétinien du modèle murin par tomographie par cohérence optique (OCT de l’anglais, Optical Coherence Tomography). Le document est divisé en deux parties importantes. Le Chapitre 1 introduit les bases théoriques nécessaires à la compréhension de la problématique, alors que le Chapitre 2 décrit les outils qui ont été développés ou adaptés durant le projet pour mener à bien les expériences. Spécifiquement, les particularités du système optique développé pour permettre
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Hámor, Peter. "Vliv dávkování genu Nkx2.5 na vývoj a elektrofyziologii srdce u myši." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-343837.

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Role of Nkx2.5 on development and electrophysiology of the mouse heart Prague 2015 Bc. Peter Hámor ABSTRACT The objective of this thesis is to investigate the role of Nkx2.5 gene dosage on electrophysiology of the mouse heart in prenatal stage of its development, in which the physiological functions of the heart fail to function properly. The main goal of this work is to search for differences in conduction of electric impulses through the embryonic mouse heart according to their genotype. Special method of capturing the conduction of electric impulse through myocardium was used for this purpo
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