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Dissertations / Theses on the topic 'Optical Tweezers'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Simpson, Neil B. "Optical spanners and improved optical tweezers." Thesis, University of St Andrews, 1998. http://hdl.handle.net/10023/14884.

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This thesis describes the experimental and theoretical work that investigated the transfer of orbital angular momentum from light to matter. This was achieved by combining two established areas of laser physics which were "optical tweezers" and Laguerre-Gaussian laser modes. The optical tweezers are essentially a tightly focussed laser beam from a high numerical aperture microscope objective lens, which traps particles in three dimensions just below the beam focus. By incorporating a Laguerre- Gaussian laser mode into the tweezers system, the trapping efficiency was doubled. These improved opt

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2

Sinclair, Gavin. "Experiments using holographic optical tweezers." Thesis, University of Glasgow, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428751.

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3

Wan, Chenchen. "Optical Tweezers Using Cylindrical Vector Beams." University of Dayton / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1353515022.

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4

Stevenson, Olivia. "Investigating myosin kinetics using optical tweezers." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416433.

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5

Stuart, Dustin L. "Manipulating single atoms with optical tweezers." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:ab99e851-3c66-4688-8725-b7d1588c5db0.

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Single atoms are promising candidates for physically implementing quantum bits, the fundamental unit of quantum information. We have built an apparatus for cooling, trapping and imaging single rubidium atoms in microscopic optical tweezers. The traps are formed from a tightly focused off-resonant laser beam, which traps atoms using the optical dipole force. The traps have a diameter of ~1 μm and a depth of ~1 mK. The novelty of our approach is the use a digital mirror device (DMD) to generate multiple independently movable tweezers from a single laser beam. The DMD consists of an array of m

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6

Mahamdeh, Mohammed. "High Resolution Optical Tweezers for Biological Studies." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-81918.

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In the past decades, numerous single-molecule techniques have been developed to investigate individual bio-molecules and cellular machines. While a lot is known about the structure, localization, and interaction partners of such molecules, much less is known about their mechanical properties. To investigate the weak, non-covalent interactions that give rise to the mechanics of and between proteins, an instrument capable of resolving sub-nanometer displacements and piconewton forces is necessary. One of the most prominent biophysical tool with such capabilities is an optical tweezers. Optical t

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7

Cheng, Jen-Hao. "Construction and characterization of an optical tweezers." FIU Digital Commons, 2003. http://digitalcommons.fiu.edu/etd/2156.

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Optical tweezers is a new technique for research in biological and physical sciences by using the radiation pressure. In this thesis, a diode laser, A = 785nm, maximum power=50mW, was used as the light source and a microscope was used for trapping and imaging. The laser pass through an anamorphic prism and provide an ideal Gaussian laser profile. Before reflecting the laser beam into the microscope, a beam expander and a convex lens expand and change the divergent angle of the laser beam for maximum power delivery and matching the imaging plane of the microscope. The trapped object was illumin

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8

Keen, Stephen Alexander Juhani. "High-speed video microscopy in optical tweezers." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1436/.

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Optical tweezers have become an invaluable tool for measuring and exerting forces in the pico-Newton regime. Force measurements have in the past concentrated on using only one trapped particle as a probe, partly due to the diﬃculties in tracking more than one par- ticle at high enough frame rate. Recent advances in video camera technology allow the collection of images at several kHz. However, there has been little use of high-speed cameras in optical tweezers, partly due to data management problems and aﬀordability. This the- sis presents seven experiments carried out during my PhD involving

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9

Jordan, Pamela Ann. "Optical tweezers for signal detection and micromanipulation." Thesis, University of Glasgow, 2005. http://theses.gla.ac.uk/1728/.

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The work presented in this thesis explores new multi-disciplinary applications of optical tweezers in the physical and biological sciences. Firstly, the three dimensional trapping of partially silvered sphere in a standard TEM00 optical trap was characterised. These spheres were then coated with an azo dye such that surface-enhanced resonance Raman (SERRS) measurements could be made on a single bead whilst it was simultaneously trapped in 532 nm optical tweezers. The length of time over which the SERRS signal could be recorded was increased, from milli-seconds to minutes, by using 1064 nm opti

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10

Brandt, Lukas. "Trapping of rubidium atoms using optical tweezers." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558210.

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This thesis describes the realisation of a novel dipole force trapping method for cold neutral atoms, the optical tweezers. They are formed by imaging a spatial light modulator onto a mirror surface, by an aspherical lens. The spatial light modulator, a digital mirror device, consists of an array 1024 by 768 of micro-mirrors, which can individually be switched between the on and off position with a full frame refresh rate of 4 kHz and hence can create arbitrary light patterns in real time. Atoms are trapped through the dipole force in them. The optical tweezers have a potential depth on the or

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11

Mitchell, Steven James. "Measurement of colloidal dynamics using optical tweezers." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393924.

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12

Lee, Michael Peter. "Techniques for optical tweezers and SLM microscopy." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5552/.

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With the development of pixelated liquid crystal displays, a new paradigm has emerged in the field of optics. Essentially, these displays enable interfacing a computer program with light, and therefore allow a wide range of light beams to be created. In this thesis, I shall be using liquid crystal displays to create phase diffraction patterns and, in this case, the displays are more commonly referred to as Spatial Light Modulators (SLMs). One area where SLMs have shown particular promise is that of optical microscopy. Here, they have been used in two different applications, namely holographic

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13

Yu, Ling Yao. "Optical and mechanical analysis on a biological cell in optical tweezers." Doctoral thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/26747.

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La réponse mécanique d'une cellule à une force externe permet d'inférer sa structure et fonction. Les pinces optiques s'avèrent une approche particulièrement attrayante pour la manipulation et caractérisation biophysique sophistiquée des cellules de façon non invasive. Cette thèse explore l’utilisation de trois types de pinces optiques couramment utilisées : 1) statiques (static), 2) à exposition partagée (time-sharing) et 3) oscillantes (oscillating). L’utilisation d’un code basé sur la méthode des éléments finis en trois dimensions (3DFEM) nous permet de modéliser ces trois types de piégeage

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14

Cui, Liyong. "An investigation into some novel areas of optical manipulation." HKBU Institutional Repository, 2017. http://repository.hkbu.edu.hk/etd_oa/436.

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Since its inception in 1970, optical manipulation has evolved into a versatile tool across many fields of science. Notably, the now widely employed optical tweezers invented in 1986 is a good example, which is in essence a strongly focused fundamental Gaussian beam. Although the optical tweezers remained as an important tool in optical manipulation, the shaped structured light such as an optical vortex beam also provides unusual light patterns and promotes exciting discoveries. This thesis is devoted to some unsolved theoretical aspects of optical manipulation. Since optical force acting on a

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15

Guo, Yabin. "Mechanical unfolding and folding studies by optical tweezers." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61185.

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As a single molecule technique, optical tweezers technique proves to be a powerful tool to investigate the physical and chemical properties of DNA/RNA and protein molecules. In this thesis, optical tweezers are applied to two studies. In the first study, we directly investigated the unfolding and folding pathways and kinetics of the wild-type Top7 with optical tweezers. The existence of a folding intermediate state is confirmed. The unfolding process also occasionally shows non-cooperative behavior which has not been observed before. To identify if the mechanical stability of an isolated fragm

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16

Carberry, David Michael, and dave_carberry@yahoo com au. "Optical Tweezers: Experimental Demonstrations of the Fluctuation Theorem." The Australian National University. Research School of Chemistry, 2006. http://thesis.anu.edu.au./public/adt-ANU20060410.122727.

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In the late 19th and early 20th centuries famous scientists like Boltzmann, Loschmidt, Maxwell and Einstein tried, unsuccessfully, to find the link between the time-reversible equations of motion of individual molecules and irreversible thermodynamics. The solution to this puzzle was found in 1993, and the link is now known as the Fluctuation Theorem (FT). In the decade that followed theory and computer simulation tested the FT and, in 2002, an experiment indirectly demonstrated the FT.¶ This thesis describes original experiments that demonstrate the FT directly using Optical Tweezers. A rela

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17

Zhou, Zhaokun. "Magneto-optical tweezers with super-resolution fluorescence microscopy." Thesis, University of York, 2017. http://etheses.whiterose.ac.uk/18771/.

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This thesis describes the design, construction and application of a novel magneto-optical tweezers with super-resolution fluorescence microscopy for manipulation, force/torque measurement and imaging of single biomolecules. The optical tweezers component offers force or position clamping in three dimensions. The 3D-printed magnetic tweezers is designated for rotation in the vertical plane. The separation of rotation from force transduction results in the capability of precise torque measurement. The filamentous biomolecules to be used in the device will lie in a transverse direction in the ima

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18

Theofanidou, Eirini. "Design, construction and biophysical applications of optical tweezers." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/11461.

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The first part of this work is dedicated to technical issues and system developments; the design and construction of an open microscope which forms the base for an optical tweezers set-up, is described. Subsequently the creation of a generic optical tweezers set-up is presented. This set-up was used in combination with two photon fluorescence to investigate the deteriorating of the quality of the trap due to optical aberrations. It is shown that using adaptive optics (i.e. a deformable membrane), the aberrations are partially corrected. Furthermore, it was demonstrated that using the deformabl

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19

Carberry, David Michael. "Optical tweezers : experimental demonstrations of the fluctuation theorem /." View thesis entry in Australian Digital Theses Program, 2005. http://thesis.anu.edu.au/public/adt-ANU20060410.122727/index.html.

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20

Yin, Munan. "Haptic optical tweezers with 3D high-speed tracking." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066003/document.

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La micromanipulation a un grand potentiel pour révolutionner la recherche biologique et les soins médicaux. À petite échelle, microrobots peuvent effectuer des tâches médicales avec peu invasive, et d'explorer la vie à un niveau fondamental. Pinces optiques sont l'une des techniques les plus populaires pour la manipulation biologique. La production de petits lots qui exige une grande flexibilité repose principalement sur le processus de téléopération. Cependant, le niveau limité d'intuitivité rend de plus en plus difficile de conduire efficacement les tâches de manipulation et d'exploration da

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21

Hay, Rebecca. "Optimising optical tweezers for tracking and force measurement experiments." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8624/.

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Optical Tweezers are a useful tool in many aspects of biology, including cell manipulation and microrheology. They are often used as piconewton force transducers, and are an effective tool for measuring forces acting upon optically trapped particle. To measure such forces, knowledge of the displacement of the particle from the trap centre is always needed. However, due to Brownian motion, a trapped particle is constantly moving and never at rest. In this case, one must track a bead over a set time, so as to gain an average displacement. In this thesis, we have improved and optimised this track

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22

Nascimento, Jaclyn Marie. "Analysis of sperm motility and physiology using optical tweezers." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3291333.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed February 14. 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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23

Preece, Daryl. "Novel uses of spatial light modulators in optical tweezers." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2619/.

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In recent years spatial light modulators (SLMs) have become an integral part of many optical trapping experiments. Yet their usefulness, which stems from their flexibility, is often under exploited. In this thesis I seek to demonstrate how it is possible to expand the range of optical trapping applications that may benefit from the use of spatial light modulators. From exploring the benefits of increased resolution to demonstrating novel applications like position clamping and polarization control, I show how SLMs are a resource which can benefit optical trapping in new and unconventional ways

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24

Abdosamadi, Mohammad K., Anita Jannasch, and Erik Schäffer. "Resonant optical tweezers with anti-reflection coated titania microspheres." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-183282.

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25

Shepherd, Jack William. "Manipulating DNA with magneto-optical tweezers and multiscale simulation." Thesis, University of York, 2018. http://etheses.whiterose.ac.uk/22040/.

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26

González, Rubio Ricardo S. M. Massachusetts Institute of Technology. "Tools to study the kinesin mechanome using optical tweezers." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/61241.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Biological Engineering, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 108-111).<br>Molecular motors play an important role in driving some of the most complex and important tasks in biological systems, ranging from transcribing RNA from a DNA template (Polymerases) to muscle contraction (Myosin) and propelling bacteria (Flagellum). Key to the understanding of the fundamental principles and designs by which molecular motor function has been the kinesin family. Missing, however, is a clear

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27

Muldoon, Cecilia. "Control and manipulation of cold atoms in optical tweezers." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:920933c8-441c-4d59-a4f4-87f8c799a820.

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The ability to address and manipulate individual information carriers in a deterministic, coherent, and scalable manner is a central theme in quantum information processing. Neutral atoms trapped by laser light are amongst the most promising candidates for storing and processing information in a quantum computer or simulator, so a scalable and flexible scheme for their control and manipulation is paramount. This thesis demonstrates a fast and versatile method to address and dynamically control the position (the motional degrees of freedom) of neutral atoms trapped in optical tweezers. The twee

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28

Abdosamadi, Mohammad K., Anita Jannasch, and Erik Schäffer. "Resonant optical tweezers with anti-reflection coated titania microspheres." Diffusion fundamentals 20 (2013) 61, S. 1, 2013. https://ul.qucosa.de/id/qucosa%3A13638.

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29

Brady, Kyle T. "ENHANCED NANOPORE DETECTION VIA DIFFUSION GRADIENTS AND OPTICAL TWEEZERS." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3798.

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Nanopore-based resistive pulse sensing represents an important class of single-molecule measurements. It provides information about many molecules of interest (i.e. DNA, proteins, peptides, clusters, polymers, etc.) without the need for labeling. Two experiments that are especially well suited for studying with nanopore sensors are DNA sequencing and DNA-protein force measurements. This thesis will describe progress that has been made in both areas. DNA sequencing has become an active area of research for stochastic single-molecule sensing, with many researchers striving for the ultimate goal

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30

Català, i. Castro Frederic. "Implementation of the direct force measurement method in optical tweezers." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/665757.

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Mechanics is the branch of physics that studies movement and force, and plays an evident role in life. The swimming dynamics of bacteria in search of nutrients, organelle transport by molecular motors or sensing different kinds of stimuli by neurons, are some of the processes that need to be explained in terms of mechanics. At a human scale, distance and force can be measured with a ruler and a calibrated spring. However, assessing these magnitudes may become an important challenge at a micron scale. Among several techniques, optical tweezers stand out as a non-invasive tool that is capable

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31

Phillips, David Benjamin. "Applications of closed-loop feedback control with holographic optical tweezers." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.570860.

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SINCE their invention, optical tweezers have found a host of applications, primarily as micro- manipulation tools and sensitive force transducers. The development of techniques such as holographic optical tweezers has enabled the manipulation of multiple particles in three dimensions. Recent advances in computation power and display technologies have afforded the opportunity to explore applications of real-time manipulation and particle tracking, utilising closed-loop feedback control, the principle aim of this work. We begin by investigating the use of holographic optical tweezers as an auton

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32

Bugiel, Michael, Elisa Böhl, and Erik Schäffer. "Diffusive protofilament switching of kinesin-8 investigated with optical tweezers." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-182342.

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33

Hui, Jeremy R. (Jeremy Ryan) 1977. "Optical tweezers using the Texas Instruments' Digital Micromirror Device(tm)." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/86699.

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Thesis (M.Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2001.<br>Includes bibliographical references.<br>by Jeremy R. Hui.<br>M.Eng.and S.B.

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34

Ta, Jenny 1982. "Antibody-Antigen assay design for combined optical tweezers and fluorescence." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/32789.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2004.<br>Includes bibliographical references (p. 37).<br>The recent development in combined optical trapping and fluorescence technology promises to enable unbindinig force studies of receptor-ligand interactions, whose specificity play a crucial role in the function of many biological systems. This thesis focuses on the development of assay designs for the study of antibody-antigen binding interactions using combined optical trapping and single molecule fluorescence. The assays create the necessary linkage

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35

Rebane, Aleksander. "Exploring Free Energy Landscapes of SNARE Assembly Using Optical Tweezers." Thesis, Yale University, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10957335.

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<p> Scientists have long sought to understand the working principles of protein machinery. A decisive step towards this goal has been the development of the Gibbs free energy landscape of protein folding. However, measurement of energy landscapes has remained challenging, particularly when folding occurs over one or more intermediates. An important example is soluble <i>N</i>-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex assembly, in which the energetics and kinetics of multiple assembly steps are coupled to distinct stages of vesicle maturation and membrane fusio

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36

Bugiel, Michael, Elisa Böhl, and Erik Schäffer. "Diffusive protofilament switching of kinesin-8 investigated with optical tweezers." Diffusion fundamentals 20 (2013) 26, S. 1, 2013. https://ul.qucosa.de/id/qucosa%3A13593.

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37

Guo, Qing. "Single Molecule Optical Magnetic Tweezers Microscopy Studies of Protein Dynamics." Bowling Green State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1435334948.

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38

Selvam, Sangeetha. "Molecular Population Dynamics of DNA Tetraplexes using Magneto-Optical Tweezers." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1516742116760289.

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39

Sudhakar, Swathi [Verfasser]. "Germanium nanospheres as high precision optical tweezers probes / Swathi Sudhakar." Tübingen : Universitätsbibliothek Tübingen, 2021. http://d-nb.info/1236994094/34.

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40

Seol, Yeonne. "Study of stochastic processes and RNA elasticity using optical tweezers." Diss., The University of Arizona, 2004. http://hdl.handle.net/10150/280567.

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Our main research project is to develop an experimental system to understand the ribosomes as molecular motors. For this purpose, we designed and developed the single molecule ribosome motility assay. In this thesis, we discuss the related steps which we have taken to develop this assay: the instrumentation and four experiments. In the introduction, we illustrate the current experimental scheme and show the preliminary data of the single molecule ribosome translation. In the first two chapters, we discuss two interesting experiments dealing with stochastic problems. In the first chapter, we in

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Brau, Ricardo R. (Ricardo Rafael) 1979. "Exploring the mechanome with optical tweezers and single molecule fluorescence." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/43795.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, February 2008.<br>Includes bibliographical references (p. 213-231).<br>The combination of optical tweezers and single molecule fluorescence into an instrument capable of making combined, coincident measurements adds an observable dimension that allows for the examination of the localized effects of applied forces on biological systems. This technological advance had remained elusive due to the accelerated photobleaching of fluorophores in the presence of the high photon flux of the optical trap. This probl

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Garbin, Valeria. "Optical tweezers for the study of microbubble dynamics in ultrasound." Doctoral thesis, Università degli studi di Trieste, 2007. http://hdl.handle.net/10077/3220.

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2005/2006<br>Optical tweezers enable for non-destructive, contact-free manipulation of ultrasound contrast agent (UCA) microbubbles, which are used in medical imaging for enhancing the echogenicity of the blood pool and to quantify organ perfusion. Understanding the dynamics of ultrasound-driven contrast agent microbubbles from a fundamental physical standpoint is a first step for exploiting their acoustical properties and to develop new diagnostic and therapeutic applications. However, experiments on bubble dynamics presently suffer from a lack of control on bubble position, because of

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YOUSAFZAI, MUHAMMAD SULAIMAN. "Cancer cell mechanics and cell microenvironment: An optical tweezers study." Doctoral thesis, Università degli Studi di Trieste, 2016. http://hdl.handle.net/11368/2908097.

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Since cancer metastasis is a complex process, lot of research has been carried out to identify different hallmarks for its diagnosis and cure. Mechanical alterations in cancer cells during cell spreading to adjacent tissues and other organs of the body emerged as a prominent hallmark in the last decade. In this thesis we employed a mechanistic approach and used stiffness (elasticity) as a marker to study cell’s mechanical response in varying microenvironmental conditions. Cell– microenvironment mechanical interaction is a blend of cell-matrix and cell-cell interactions. Therefore we adopted

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Wray, John. "INVESTIGATING THE POTENTIAL APPLICATIONS OF A RAMAN TWEEZER SYSTEM." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/3135.

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This thesis describes the construction of an Optical Tweezer apparatus to be used in conjunction with a confocal Raman spectrometer. The tweezer utilizes an infrared (λ=1064 nm) laser directed into an inverted microscope with NA=1.4 oil immersion 100x objective lens that strongly focuses the laser light into a sample to function as a single-beam gradient force trap. The long term goal of this research program is to develop a single molecule Raman tweezers apparatus that allows one to control the position of a Raman nanoplasmonic amplifier. This thesis describes the construction of the Raman tw

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Latinovic, Olga S. "Structural and micromechanical properties of soft materials : An optical tweezers study /." Diss., [Free access to full dissertation available to Lehigh users only.], 2005. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3203821.

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46

Shirdel, Mariam. "Probing protein - Pili interactions by optical tweezers and 3D molecular modelling." Thesis, Umeå universitet, Institutionen för fysik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-68747.

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47

Wang, Na 1982. "System of measuring mechanical properties of colloidal gels with optical tweezers." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101662.

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Due to the unique rheological properties of colloidal gels, gelation of colloidal suspensions has become increasingly important to fundamental investigations, as well as to technological applications. Recent experimental approaches are mainly focused on the bulk properties of colloidal gels, using methods of static and dynamic light scattering and shear rheometry. This thesis describes the development of a system for measuring the mechanical properties of colloidal gels with optical tweezers.<br>We make colloidal gels out of polystyrene beads of two different sizes, diameters of 3.5mum or 62nm

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48

Orta, Alberto. "Development and automation of optical tweezers for single biomolecule force measurements." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493322.

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Zhang, Hanqing. "Construction of an Optical Tweezers Instrumentation and Validation of Brownian motion." Thesis, Umeå universitet, Institutionen för fysik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-94771.

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We constructed a standalone optical trapping system that was steerable in three dimensions and allowed for sufficient imaging of one цm particles with a CCD camera. The motion of the trapped particles was monitored by both a position sensitive detector as well with the CCD camera. The trap stiffness was evaluated by the power spectrum method and the equipartition theorem. For calibration of the stiffness of the trap, we found that the power spectrum method with data assessed by the PSD was most straightforward and accurate. The equipartition method was compromised by noise, low resolution and

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Buajarern, Jariya. "Fundamental studies of inorganic and organic aqueous aerosols using optical tweezers." Thesis, University of Bristol, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439956.

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