Relevant bibliographies by topics / Optogenetic mapping

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Optogenetic mapping'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Optogenetic mapping"

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Li, Gongxin, Jia Yang, Yuechao Wang, Wenxue Wang, and Lianqing Liu. "Development of a novel optogenetic indicator based on cellular deformations for mapping optogenetic activities." Nanoscale 10, no. 45 (2018): 21046–51. http://dx.doi.org/10.1039/c8nr05014g.

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Matsuzaki, Masanori. "Transcranial optogenetic mapping of the mouse motor cortex." Neuroscience Research 65 (January 2009): S19. http://dx.doi.org/10.1016/j.neures.2009.09.1594.

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Chen, Yi, Filip Sobczak, Patricia Pais-Roldán, Cornelius Schwarz, Alan P. Koretsky, and Xin Yu. "Mapping the Brain-Wide Network Effects by Optogenetic Activation of the Corpus Callosum." Cerebral Cortex 30, no. 11 (2020): 5885–98. http://dx.doi.org/10.1093/cercor/bhaa164.

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Abstract Optogenetically driven manipulation of circuit-specific activity enables causality studies, but its global brain-wide effect is rarely reported. Here, we applied simultaneous functional magnetic resonance imaging (fMRI) and calcium recording with optogenetic activation of the corpus callosum (CC) connecting barrel cortices (BC). Robust positive BOLD was detected in the ipsilateral BC due to antidromic activity, spreading to the ipsilateral motor cortex (MC), and posterior thalamus (PO). In the orthodromic target, positive BOLD was reliably evoked by 2 Hz light pulses, whereas 40 Hz li
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Lin, Gang, Wenyi Shi, Ningxia Zhang, Yi-Tsang Lee, Youjun Wang, and Ji Jing. "Proteomic mapping and optogenetic manipulation of membrane contact sites." Biochemical Journal 479, no. 17 (2022): 1857–75. http://dx.doi.org/10.1042/bcj20220382.

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Membrane contact sites (MCSs) mediate crucial physiological processes in eukaryotic cells, including ion signaling, lipid metabolism, and autophagy. Dysregulation of MCSs is closely related to various diseases, such as type 2 diabetes mellitus (T2DM), neurodegenerative diseases, and cancers. Visualization, proteomic mapping and manipulation of MCSs may help the dissection of the physiology and pathology MCSs. Recent technical advances have enabled better understanding of the dynamics and functions of MCSs. Here we present a summary of currently known functions of MCSs, with a focus on optical
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Niemeyer, James E. "Mapping whole brain seizure network recruitment with optogenetic kindling." Journal of Neurophysiology 127, no. 2 (2022): 393–96. http://dx.doi.org/10.1152/jn.00525.2021.

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Epilepsy is often labeled as a network disorder, though a common view of seizures holds that they initiate in a singular onset zone before expanding contiguously outward. A recent report by Choy et al. (Choy M, Dadgar-Kiani E, Cron GO, Duffy BA, Schmid F, Edelman BJ, Asaad M, Chan RW, Vahdat S, Lee JH. Neuron 2021 Oct 23: S0896-6273(21)00778-9.) leverages new tools to study whole brain dynamics during epileptic seizures originating in the hippocampus. Cell-type-specific kindling and functional imaging revealed how various brain regions were recruited to seizures and uncovered a novel form of m
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Hira, Riichiro, Fuki Okubo, Naoki Honkura, et al. "Transcranial optogenetic stimulation for mapping of the motor cortex." Neuroscience Research 65 (January 2009): S201. http://dx.doi.org/10.1016/j.neures.2009.09.1099.

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Wu, Ling, Ao Dong, Liting Dong, Shi-Qiang Wang, and Yulong Li. "PARIS, an optogenetic method for functionally mapping gap junctions." IBRO Reports 6 (September 2019): S392. http://dx.doi.org/10.1016/j.ibror.2019.07.1245.

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Zaglia, Tania, Nicola Pianca, Giulia Borile, et al. "Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2." Proceedings of the National Academy of Sciences 112, no. 32 (2015): E4495—E4504. http://dx.doi.org/10.1073/pnas.1509380112.

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Extrasystoles lead to several consequences, ranging from uneventful palpitations to lethal ventricular arrhythmias, in the presence of pathologies, such as myocardial ischemia. The role of working versus conducting cardiomyocytes, as well as the tissue requirements (minimal cell number) for the generation of extrasystoles, and the properties leading ectopies to become arrhythmia triggers (topology), in the normal and diseased heart, have not been determined directly in vivo. Here, we used optogenetics in transgenic mice expressing ChannelRhodopsin-2 selectively in either cardiomyocytes or the
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Schmid, Florian, Lydia Wachsmuth, Miriam Schwalm, et al. "Assessing sensory versus optogenetic network activation by combining (o)fMRI with optical Ca2+ recordings." Journal of Cerebral Blood Flow & Metabolism 36, no. 11 (2016): 1885–900. http://dx.doi.org/10.1177/0271678x15619428.

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Encoding of sensory inputs in the cortex is characterized by sparse neuronal network activation. Optogenetic stimulation has previously been combined with fMRI (ofMRI) to probe functional networks. However, for a quantitative optogenetic probing of sensory-driven sparse network activation, the level of similarity between sensory and optogenetic network activation needs to be explored. Here, we complement ofMRI with optic fiber-based population Ca2+ recordings for a region-specific readout of neuronal spiking activity in rat brain. Comparing Ca2+ responses to the blood oxygenation level-depende
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Stucynski, J., A. Schott, J. Baik, J. Hong, F. Weber, and S. Chung. "0074 Inhibitory Neurons in the Dorsomedial Medulla Promote REM Sleep." Sleep 43, Supplement_1 (2020): A30. http://dx.doi.org/10.1093/sleep/zsaa056.072.

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Abstract Introduction The neural circuits controlling rapid eye movement (REM) sleep, and in particular the role of the medulla in regulating this brain state, remains an active area of study. Previous electrophysiological recordings in the dorsomedial medulla (DM) and electrical stimulation experiments suggested an important role of this area in the control of REM sleep. However the identity of the involved neurons and their precise role in REM sleep regulation are still unclear. Methods The properties of DM GAD2 neurons in mice were investigated through stereotaxic injection of CRE-dependent
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Dissertations / Theses on the topic "Optogenetic mapping"

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Lim, Diana Heather. "Development and application of large-scale optogenetic mapping in the mouse cortex." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/52355.

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One of the major goals in neuroscience is to understand and map the connectivity of the brain. While this is no small undertaking, recent technological advances have allowed brain mapping to reach unprecedented levels. Optogenetic tools have been developed that permit selective manipulation and investigation of neural systems. Here, we have mapped in vivo intracortical activity in the mouse by combining arbitrary point optogenetic stimulation and regional voltage-sensitive dye (VSD) imaging. We first show that optogenetic photostimulation using channelrhodopsin-2 (ChR2) led to cortical maps t
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Chen, Yi [Verfasser]. "Mapping the local and brain-wide network effects by optogenetic activation with an MRI-guided robotic arm / Yi Chen." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1214640044/34.

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Zhang, Sarah. "Assessing Motor Impairments in a Mouse Model of Perinatal Stroke Through Brain Mapping and Behaviour." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40854.

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Perinatal stroke, which occurs before or shortly after birth, may result in both beneficial and maladaptive plasticity in surviving tissue. However, current preclinical and clinical work have an unclear understanding on the relationship between functional outcome and neurophysiology. This thesis aims to dually characterize and correlate behaviour with cortical motor representations in a mouse model of perinatal stroke. On postnatal day 7, a unilateral photothrombotic stroke was produced in the primary motor cortex of Thy1-ChR2 mice. Sensorimotor function was evaluated in adulthood with a batte
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Conti, Emilia. "In vivo optical imaging of cortical plasticity induced by rehabilitation after stroke." Doctoral thesis, 2019. http://hdl.handle.net/2158/1152568.

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In my PhD thesis I have studied the changes in functional and structural plasticity induced by a photothrombotic stroke in mouse primary motor cortex. In order to dissect the multiple aspects consequent to the damage we exploit fluorescent imaging techniques that allow to investigate the functional and structural rearrangement of the cortex at different scale, from the entire hemisphere, with wide-field calcium imaging, up to the single synapse with two-photon microscopy. To promote a functional recovery of the mouse forelimb we applied different rehabilitative strategies in order to both fos
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Adams, Cameron Darcy. "Channelrhodopsin-assisted circuit mapping of medial amygdaloid connectivity to the paraventricular nucleus of the hypothalamus." Thesis, 2018. http://hdl.handle.net/1959.13/1387401.

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Research Doctorate - Doctor of Philosophy (PhD)<br>Understanding how the brain is connected is an important first step if we are to successfully treat its conditions. Currently, much of what we know about the brain connectome has been discovered through neuroanatomical tracing studies. This approach however, lacks functionality in that we cannot determine the physiological consequences of manipulating a given pathway or its overall necessity to a specific behavioural outcome. Dysregulated social and emotional functioning, including hypothalamic-pituitary-adrenal (HPA) axis responses, are cardi
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Montagni, Elena, Francesco Resta, Giuseppe de Vito, Alessandro Scaglione, Anna Letizia Allegra Mascaro, and Francesco Saverio Pavone. "ALL-OPTICAL FUNCTIONAL MAPPING OF THE FORELIMB MOTOR CORTEX REVEALS TWO DISTINCT GRASPING CORTICAL REPRESENTATIONS." Doctoral thesis, 2021. http://hdl.handle.net/2158/1236473.

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The anatomical and functional organization of the motor cortex and its role in forelimb movement control were deeply investigated over the past years. Extensive research showed two spatially segregated functional areas related to forelimb control: the caudal forelimb area (CFA) and the rostral forelimb area (RFA). Many studies suggest that these two areas are a part of a highly integrated computational unit with distinct motor functions. Recently, optogenetic motor mapping revealed that distinct complex movements are related to segregated cortical functional modules. Although studying optogene
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(6803957), Qiuyu Wu. "MAPPING BRAIN CIRCUITS IN HEALTH AND DISEASE." Thesis, 2019.

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<p>Intricate neural circuits underlie all brain functions. However, these neural circuits are highly dynamic. The ability to change, or the plasticity, of the brain has long been demonstrated at the level of isolated single synapses under artificial conditions. Circuit organization and brain function has been extensively studied by correlating neuronal activity with information input. The primary visual cortex has become an important model brain region for the study of sensory processing, in large part due to the ease of manipulating visual stimuli. Much has been learned from studies of visual
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Books on the topic "Optogenetic mapping"

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Appasani, Krishnarao. Optogenetics: From Neuronal Function to Mapping and Disease Biology. Cambridge University Press, 2017.

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Appasani, Krishnarao. Optogenetics: From Neuronal Function to Mapping and Disease Biology. Cambridge University Press, 2017.

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Handbook of Neurophotonics. Taylor & Francis Group, 2020.

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Pavone, Francesco S., and Shy Shoham. Handbook of Neurophotonics. Taylor & Francis Group, 2020.

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Pavone, Francesco S., and Shy Shoham. Handbook of Neurophotonics. Taylor & Francis Group, 2020.

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Pavone, Francesco S., and Shy Shoham. Handbook of Neurophotonics. Taylor & Francis Group, 2020.

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Pavone, Francesco S., and Shy Shoham. Handbook of Neurophotonics. Taylor & Francis Group, 2020.

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Book chapters on the topic "Optogenetic mapping"

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Kyweriga, Michael, and Majid H. Mohajerani. "Optogenetic Approaches for Mesoscopic Brain Mapping." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3512-3_17.

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Backhaus, Hendrik, Nicolas Ruffini, Anna Wierczeiko, and Albrecht Stroh. "An All-Optical Physiology Pipeline Toward Highly Specific and Artifact-Free Circuit Mapping." In Neuromethods. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2764-8_5.

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AbstractAll-optical physiology of neuronal microcircuits requires the integration of optogenetic perturbation and optical imaging, efficient opsin and indicator co-expression, and tailored illumination schemes. It furthermore demands concepts for system integration and a dedicated analysis pipeline for calcium transients in an event-related manner. Here, firstly, we put forward a framework for the specific requirements for technical system integration particularly focusing on temporal precision. Secondly, we devise a step-by-step guide for the image analysis in the context of an all-optical ph
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Conference papers on the topic "Optogenetic mapping"

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Khanal, Nischal, Jonah Padawer-Curry, Trevor Voss, Kevin Schulte, Annie Bice, and Adam Q. Bauer. "Multi-limbed optogenetic motor mapping in awake mice reveals cortical organization of coordinated movements." In Optogenetics and Optical Manipulation 2025, edited by Anna W. Roe and Shy Shoham. SPIE, 2025. https://doi.org/10.1117/12.3042322.

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Augustine, George J., Ken Berglund, Harin Gill, et al. "Optogenetic mapping of brain circuitry." In SPIE Nanosystems in Engineering + Medicine, edited by Sang H. Choi, Jin-Ho Choy, Uhn Lee, and Vijay K. Varadan. SPIE, 2012. http://dx.doi.org/10.1117/12.2008665.

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Augustine, George J., Susu Chen, Harin Gill, et al. "High-speed optogenetic circuit mapping." In SPIE BiOS, edited by Samarendra K. Mohanty and Nitish V. Thakor. SPIE, 2013. http://dx.doi.org/10.1117/12.2012404.

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Lee, Jin-Hyung. "Brain Activity Mapping with Optogenetic Functional Magnetic Resonance Imaging." In CLEO: Applications and Technology. OSA, 2013. http://dx.doi.org/10.1364/cleo_at.2013.jf2l.2.

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Padawer-Curry, Jonah A., Nischal Khanal, Evan W. Morris, Annie R. Bice, and Adam Q. Bauer. "Cortical Organization of Ethological-like, Multi-Limb Movements." In Optics and the Brain. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/brain.2024.bm5c.4.

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We performed optogenetic motor mapping in combination with a markerless pose estimation algorithm, DeeplabCut (DLC) to characterize unrestricted motor responses. Assessment of multi-limb movements revealed ethological-like behaviors, topographically organized on the cortex.
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Narcisse, Darryl, Sourajit M. Mustafi, Michael Carlson, Subrata Batabyal, Weldon W. Wright, and Samarendra K. Mohanty. "Optical modulation and functional mapping of cortical activities using molecular actuator-sensor." In Optogenetics and Optical Manipulation 2020, edited by Samarendra K. Mohanty, Anna W. Roe, and E. Duco Jansen. SPIE, 2020. http://dx.doi.org/10.1117/12.2546950.

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Khanal, Nischal, Kevin Schulte, Trevor Voss, et al. "Automated light-based motor mapping of multiple limb movements in mice using deep neural networks." In Optogenetics and Optical Manipulation 2021, edited by Samarendra K. Mohanty, Anna W. Roe, and Shy Shoham. SPIE, 2021. http://dx.doi.org/10.1117/12.2578860.

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Padawer-Curry, Jonah A., Adam Q. Bauer, and Nischal Khanal. "Integrated light-based motor mapping with deep neural networks for tracking multiple limb movements in mice." In Optogenetics and Optical Manipulation 2022, edited by Samarendra K. Mohanty, Anna W. Roe, and Shy Shoham. SPIE, 2022. http://dx.doi.org/10.1117/12.2610258.

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