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Journal articles on the topic 'Oral Antidiabetic'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Nana, Nurhasanah Rumanda, Khairunnisa, and Urip Harahap. "Potential Drug Interactions Of Oral Antidiabetic In Prescriptions Of Type 2 Diabetes Mellitus Patients At Kumpulan Pane Hospital." International Journal of Science, Technology & Management 2, no. 4 (2021): 1378–82. http://dx.doi.org/10.46729/ijstm.v2i4.278.

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    Diabetes Mellitus is a disease that can cause complications of other diseases so that the treatment to be given becomes more and this has the potential for interactions between drugs that can affect the physiological condition of the patient. The aim of this study is to analyze the potential of oral antidiabetic interactions on prescription at Kumpulan Pane Hospital. Analysis of potential oral antidiabetic interactions on a prescription using quantitative research methods is retrospective descriptive. Prescriptions used are inpatient and outpatient prescriptions for

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2

Lukito, Johan Indra. "Antidiabetik Oral Kombinasi Penghambat DPP-4 dan Penghambat SGLT-2." Cermin Dunia Kedokteran 48, no. 12 (2021): 692–95. http://dx.doi.org/10.55175/cdk.v48i12.157.

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Dalam tatalaksana diabetes melitus tipe 2, terapi kombinasi dua obat antidiabetik disarankan jika dengan monoterapi gagal mencapai target kontrol glikemik. Pemilihan jenis obat antidiabetik tergantung kondisi pasien dan profil obat. Kombinasi obat antidiabetik oral golongan penghambat DPP-4 (dipeptidyl peptidase-4) dan penghambat SGLT-2 (sodium-glucose cotransporter type 2) dapat menjadi salah satu pilihan. Combination of two antidiabetic drugs is recommended in the management of type 2 diabetes mellitus if monotherapy fails to achieve glycemic control targets. Choice of antidiabetic dru

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3

Lukito, Johan Indra. "Antidiabetik Oral Kombinasi Penghambat DPP-4 dan Penghambat SGLT-2." Cermin Dunia Kedokteran 48, no. 12 (2021): 692. http://dx.doi.org/10.55175/cdk.v48i12.1572.

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<p>Dalam tatalaksana diabetes melitus tipe 2, terapi kombinasi dua obat antidiabetik disarankan jika dengan monoterapi gagal mencapai target kontrol glikemik. Pemilihan jenis obat antidiabetik tergantung kondisi pasien dan profil obat. Kombinasi obat antidiabetik oral golongan penghambat DPP-4 (dipeptidyl peptidase-4) dan penghambat SGLT-2 (sodium-glucose cotransporter type 2) dapat menjadi salah satu pilihan.</p><p>Combination of two antidiabetic drugs is recommended in the management of type 2 diabetes mellitus if monotherapy fails to achieve glycemic control targets. Choic

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4

Dascultu, Dana Adriana, Elena Madalina Petran, and Coriolan Emil Ulmeanu. "Epidemiology in oral antidiabetic poisoning in children and adolescents – a four-year study in a pediatric poison centre." Romanian Journal of Pediatrics 70, no. 1 (2021): 53–57. http://dx.doi.org/10.37897/rjp.2021.1.10.

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Oral antidiabetics have become a common etiology associated with acute poisoning in children. The study shall carry out an analysis of the demographic characteristics, circumstantial characteristics and clinical profile associated with oral antidiabetic poisoning. An observational, descriptive and retrospective study was carried out over a period of 4 years including children confirmed with the diagnosis of acute poisoning with oral antidiabetics. In the study group, there is a prevalence of voluntary acute poisoning in female patients in the 15 to 18 year age group. bIn the group study biguan

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5

Lebovitz, Harold E. "Oral Antidiabetic Agents." Drugs 44, Supplement 3 (1992): 21–28. http://dx.doi.org/10.2165/00003495-199200443-00004.

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6

Scheen, J., and Pierre J. Lef??bvre. "Oral Antidiabetic Agents." Drugs 55, no. 2 (1998): 225–36. http://dx.doi.org/10.2165/00003495-199855020-00004.

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7

Krentz, Andrew J., and Clifford J. Bailey. "Oral Antidiabetic Agents." Drugs 65, no. 3 (2005): 385–411. http://dx.doi.org/10.2165/00003495-200565030-00005.

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8

Melander, A., L. O. Almér, G. Sartor, B. Scherstén, and E. Wåhlin-Boll. "Oral Antidiabetic Therapy." Acta Medica Scandinavica 210, S656 (2009): 55–57. http://dx.doi.org/10.1111/j.0954-6820.1982.tb07704.x.

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9

Hidayati, Nur Rahmi, Dyah Aryani Perwitasari, Imaniar Noor Faridah, and Rinto Susilo. "Effect of Gene Polymorphisms on Oral Antidiabetic Drug Response in Patients With Type 2 Diabetes Mellitus." Sciences of Pharmacy 4, no. 2 (2025): 72–80. https://doi.org/10.58920/sciphar0402321.

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Diabetes mellitus is currently one of the global health threats. The prevalence and incidence of this disease continue to increase, both in industrialised and developing countries, including Indonesia. There are different types of DM marker gene polymorphisms in each racial group. These genetic variations contribute to the response of oral antidiabetic drugs. This article aims to conduct a narrative review of the influence of gene polymorphisms on oral antidiabetic drug response in patients with type 2 diabetes mellitus. Article searches were conducted in PubMed, Scopus, Google Scholar, and Wi

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10

Bintang, Sri. "EVALUASI ORAL ANTIDIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD "X" LAMONGAN." Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) 2, no. 1 (2021): 1. http://dx.doi.org/10.30587/herclips.v2i1.2188.

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Diabetes Mellitus Type 2 is a metabolic disorder characterized by an increase in blood sugar due to decreased insulin secretion by pancreatic beta cells and or insulin function disorders (insulin resistance). This study aims to evaluate oral antidiabetics in patients with type 2 diabetes mellitus at the Regional General Hospital dr. Soegiri Lamongan. This research design is descriptive with a population of all type 2 diabetes mellitus patients from July to August 2019 using a total sampling technique. The number of samples in this study were 64 patients. The results showed that the most prescr

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11

Lebovitz, Harold E. "Oral antidiabetic agents: 2004." Medical Clinics of North America 88, no. 4 (2004): 847–63. http://dx.doi.org/10.1016/j.mcna.2004.05.002.

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12

Kaye, Todd B. "Triple Oral Antidiabetic Therapy." Journal of Diabetes and its Complications 12, no. 6 (1998): 311–13. http://dx.doi.org/10.1016/s1056-8727(98)00013-0.

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13

Cavallo Perin, Paolo, and Paolo Fornengo. "New oral antidiabetic agents." Internal and Emergency Medicine 6, S1 (2011): 135–38. http://dx.doi.org/10.1007/s11739-011-0677-5.

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14

Somogyi, Anikó. "Oral antidiabetic drugs in chronic renal diseases." Orvosi Hetilap 153, no. 44 (2012): 1727–31. http://dx.doi.org/10.1556/oh.2012.29482.

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Decline in renal function may increase plasma concentration of several drugs – including oral antidiabetics – with a possible need for dose adjustment in this patient population. In this review, the pathophysiology and progression of diabetic kidney diseases is summarized. Guidance is given about appropriate administration of oral antidiabetic drugs in chronic kidney diseases, based on approved product label information. In addition to pioglitazon, recent availability of the new dipeptidyl peptidase-4 inhibitor linagliptin provides another option for diabetic patients with renal impairment wit

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15

Lumbantobing, Romauli, and ,. Kurniyanto. "Comparison of the Effectiveness of Single Oral Antidiabetic Drugs with Combination Antidiabetic Drugs in Lowering Blood Sugar in Type 2 Diabetes Mellitus Patients at UKI General Hospital in 2014-2017." Journal of Drug Delivery and Therapeutics 12, no. 1-S (2022): 118–22. http://dx.doi.org/10.22270/jddt.v12i1-s.5219.

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Diabetes Mellitus is a disease characterized by hyperglycemia or the glucose in the blood increased or beyond ordinary. The national prevalence of Diabetes Mellitus in Indonesia is 6,9%. Patients with Diabetes Mellitus can be given antidiabetic drugs such as sulfonylurea and glinid. The antidiabetic drug can be consumed as a combination or single. This study aims to determine whether there is a significant efficacy comparison between antidiabetic combination therapy and single antidiabetic therapy. This study is a retrospective casual research by looking at the medical record. From 30 patients

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16

Locatelli, Anna, Sara Ornaghi, Alessandra Terzaghi, et al. "Antidiabetic Therapy during Pregnancy: The Prescription Pattern in Italy." International Journal of Environmental Research and Public Health 20, no. 23 (2023): 7139. http://dx.doi.org/10.3390/ijerph20237139.

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Pregestational and gestational diabetes mellitus are relevant complications of pregnancy, and antidiabetic drugs are prescribed to obtain glycemic control and improve perinatal outcomes. The objective of this study was to describe the prescription pattern of antidiabetics before, during and after pregnancy in Italy and to evaluate its concordance with the Italian guideline on treatment of diabetes mellitus. A multi-database cross-sectional population study using a Common Data Model was performed. In a cohort of about 450,000 women, the prescribing profile of antidiabetics seemed to be in line

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17

Pujilestari, Mardiana, Arina Titami, and Sugiyono Sugiyono. "The Relationship Between Oral Antidiabetic Treatment And Blood Sugar Level Among Type 2 Diabetes Mellitus Patients in Nur Hidayah Hospital Yogyakarta." Disease Prevention and Public Health Journal 19, no. 1 (2025): 52–58. https://doi.org/10.12928/dpphj.v19i1.11948.

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Background: Diabetes mellitus is a chronic disease that poses a global health threat, with type 2 diabetes mellitus accounts for 90% of all cases. In Indonesia, diabetes mellitus is among the causes of high mortality due to non-communicable diseases. If not treated properly, type 2 diabetes mellitus can lead to various complications, potentially worsening the patient's condition. To address this, blood glucose levels must be controlled through the use of oral antidiabetic medications, either as monotherapy or in combination therapy. This study aims to the accuracy of oral antidiabetic drugs us

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18

Ordelheide, Anna-Maria, Martin Hrabě de Angelis, Hans-Ulrich Häring, and Harald Staiger. "Pharmacogenetics of oral antidiabetic therapy." Pharmacogenomics 19, no. 6 (2018): 577–87. http://dx.doi.org/10.2217/pgs-2017-0195.

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19

Vlckova, Veronika, Victoria Cornelius, Rachna Kasliwal, Lynda Wilton, and Saad A. W. Shakir. "Hypoglycaemia with Oral Antidiabetic Drugs." Drug Safety 32, no. 5 (2009): 409–18. http://dx.doi.org/10.2165/00002018-200932050-00004.

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20

Spiller, H. A. "Toxicology of oral antidiabetic medications." American Journal of Health-System Pharmacy 63, no. 10 (2006): 929–38. http://dx.doi.org/10.2146/ajhp050500.

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21

Mehanna, Ahmed S. "Insulin and Oral Antidiabetic Agents." American Journal of Pharmaceutical Education 69, no. 5 (2005): 89. http://dx.doi.org/10.5688/aj690589.

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22

Kleinsorge, H. "Carbutamide — The first oral antidiabetic." Experimental and Clinical Endocrinology & Diabetes 106, no. 02 (2009): 149–51. http://dx.doi.org/10.1055/s-0029-1211968.

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23

Becker, Matthijs L., Ewan R. Pearson, and Ivan Tkáč. "Pharmacogenetics of Oral Antidiabetic Drugs." International Journal of Endocrinology 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/686315.

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Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register studies, but only a handful of associations detected in these studies were replicated. The gene variants inCYP2C9,ABCC8/KCNJ11, andTCF7L2were associated with the effect of sulfonylureas.CYP2C9encodes sulfonylurea metabolizing cytochrome P450 isoenzyme 2C9,ABCC8andKCNJ11genes encode proteins constituting ATP-sensitive K+channel which is a thera

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24

Melander, A. "Oral Antidiabetic Drugs: an Overview." Diabetic Medicine 13 (September 1996): 143–47. http://dx.doi.org/10.1002/dme.1996.13.s6.143.

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25

Kapoor, Nitin, and Nihal Thomas. "Oral antidiabetic agents: Recently available novel oral antidiabetic agents in India: A clinical review." Current Medical Issues 15, no. 3 (2017): 169. http://dx.doi.org/10.4103/cmi.cmi_39_17.

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26

Putri, Lesi Kurnia, Jazil Karimi, and Dimas Pramita Nugraha. "Profil Pengendalian Diabetes Melitus Tipe 2 Di Poliklinik Penyakit Dalam RSUD Arifin Achmad Pekanbaru." Jurnal Ilmu Kedokteran 8, no. 1 (2017): 18. http://dx.doi.org/10.26891/jik.v8i1.2014.18-24.

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Management in patients with type 2 diabetes mellitus (DM) is aimed diabetic control required antidiabetic drugs(OAD). The aim of this study was to know data about the profile of diabetics control in patients with type 2 diabetesmellitus followed in department of endocrinology Arifin Achmad General Hospital Pekanbaru. The type of researchwas descriptive. The samples are 96 people included all patients with type 2 DM according to inclusion criteria. Theidentity patients and patients knowledge were determined using questionnaire, used of antidiabetics drugs and diabeticcontrol were detemined usin

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27

Marković, Aleksandra, Tamara Dojčinović, Ivona Risović, Milorad Grujičić, and Jelena Malinović-Pančić. "Secondary failure of oral therapy in patients with type 2 diabetes: How to overcome it?" Scripta Medica 56, no. 1 (2025): 93–98. https://doi.org/10.5937/scriptamed56-52683.

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Background/Aim: Secondary failure of oral therapy occurs after a long period of successful use of oral antidiabetic drugs. The exact mechanism of its occurrence is not known. Recent data suggest heterogeneity of this phenomenon, analogous that of type 2 diabetes pathogenesis. Research objective was to assess glucoregulation and insulin secretory function before, three months after the use of insulin therapy and three months after the exclusion and re-introduction of oral antidiabetic therapy. Methods: Forty-nine patients with unsatisfactory glycaemic control were selected and insulin therapy i

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28

Shahzad, Naiyer. "Monitoring of adverse drug reactions in individuals with type 2 diabetes mellitus receiving oral hypoglycemic agents." Journal of Umm Al-Qura University for Medical Sciences 9, no. 1 (2023): 37–44. http://dx.doi.org/10.54940/ms84792341.

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Background: This study intends to ascertain the prevalence and overall burden of various adverse drug reactions (ADRs) driven by oral antidiabetics for treating type II diabetes mellitus (T2DM) in India. Methods: Patients with T2DM taking oral antidiabetic medications participated in prospective observational research. Data collection used the pretested format by the Indian pharmacovigilance program to record the history of drugs suspected to be responsible for ADRs. The causality evaluation is according to the guidelines of the Uppsala Monitoring Center and the World Health Organization. Resu

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29

Koski, Renee R. "Oral Antidiabetic Agents: A Comparative Review." Journal of Pharmacy Practice 17, no. 1 (2004): 39–48. http://dx.doi.org/10.1177/0897190003261307.

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Type 2 diabetes mellitus is a chronic disease characterized by insulin resistance, impaired insulin secretion, and/or increased hepatic glucose production. The mainstays of drug treatment are the oral antidiabetic agents. Insulin is usually reserved for patients who do not achieve fasting plasma glucose or A1C goals with or cannot tolerate the oral antidiabetic agents. There are 5 classes of oral antidiabetic agents available in the United States: sulfonylureas, biguanides, alpha-glucosidase inhibitors, thiazolidinediones, and nonsulfonylurea secretagogues. They have differences and similariti

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30

Zaputovic, Luka, Zeljka Rubesa Miculinic, Sanja Matijevic Roncevic, David Gobic, and Teodora Zaninovic Jurjevic. "Cardiovascular Safety of Oral Antidiabetic Drugs." Cardiologia Croatica 11, no. 7 (2016): 285–94. http://dx.doi.org/10.15836/ccar2016.285.

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31

Talantov, V. V., and N. V. Kupriyanova-Ashina. "Chronic overdose of oral antidiabetic drugs." Kazan medical journal 74, no. 1 (1993): 12–13. http://dx.doi.org/10.17816/kazmj64591.

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The introduction of new drugs into medical practice is accompanied by the need to solve such a problem as the correct choice of the drug, the identification of its toxic manifestations and side effects. Of practical importance is the syndrome of chronic insulin overdose (CSI) - Samoji syndrome, which is characterized by paradoxical hyperglycemia in response to an increase in the dose of insulin.

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32

Abbatecola, Angela Marie, Giuseppe Paolisso, Andrea Corsonello, Silvia Bustacchini, and Fabrizia Lattanzio. "Antidiabetic Oral Treatment in Older People." Drugs & Aging 26, Supplement 1 (2009): 53–62. http://dx.doi.org/10.2165/11534660-000000000-00000.

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33

Selvaag, Edgar. "Photohemolysis Due to Oral Antidiabetic Drugs." Journal of Toxicology: Cutaneous and Ocular Toxicology 16, no. 4 (1997): 217–26. http://dx.doi.org/10.3109/15569529709048900.

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34

Kalliokoski, Annikka, Pertti J. Neuvonen, and Mikko Niemi. "SLCO1B1 Polymorphism and Oral Antidiabetic Drugs." Basic & Clinical Pharmacology & Toxicology 107, no. 4 (2010): 775–81. http://dx.doi.org/10.1111/j.1742-7843.2010.00581.x.

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35

Dolger, Henry. "AN ASSESSMENT OF ORAL ANTIDIABETIC THERAPY." Annals of the New York Academy of Sciences 82, no. 2 (2006): 531–36. http://dx.doi.org/10.1111/j.1749-6632.1959.tb44932.x.

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36

Macfarlane, D. P., K. R. Paterson, and M. Fisher. "Oral antidiabetic agents as cardiovascular drugs." Diabetes, Obesity and Metabolism 9, no. 1 (2007): 23–30. http://dx.doi.org/10.1111/j.1463-1326.2006.00592.x.

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37

Fink, Anne, and Britta Haenisch. "Oral antidiabetic drugs and dementia risk." Neurology 89, no. 18 (2017): 1848–49. http://dx.doi.org/10.1212/wnl.0000000000004613.

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38

Laight, David. "The pharmacology of oral antidiabetic agents." Nurse Prescribing 12, no. 12 (2014): 604–7. http://dx.doi.org/10.12968/npre.2014.12.12.604.

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39

Sredy, Janet, and Jay Wrobel. "Vanadate as an oral antidiabetic agent." Expert Opinion on Investigational Drugs 3, no. 12 (1994): 1277–80. http://dx.doi.org/10.1517/13543784.3.12.1277.

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40

Nattrass, Malcolm. "Repaglinide: a novel oral antidiabetic agent." Hospital Medicine 61, no. 2 (2000): 112–15. http://dx.doi.org/10.12968/hosp.2000.61.2.1275.

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41

Pareek, Manan, and Deepak L. Bhatt. "Oral Antidiabetic Agents and Cardiovascular Outcomes." Current Problems in Cardiology 43, no. 3 (2018): 111–26. http://dx.doi.org/10.1016/j.cpcardiol.2017.07.003.

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42

Ahlan Sangkal, Rahmat Ismail, and Febrianika Ayu Kusumaningtyas. "Activity Test of N-Hexane Fraction of Takokak Fruit ( Solanum torvum Swartz ) Using Glucose Tolerance Test Method Per Oral (OGTT) in Test Animals White Rats (Rattus norvegicus)." International Journal of Public Health 1, no. 4 (2024): 199–210. https://doi.org/10.62951/ijph.v1i4.265.

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Takokak fruit contains bioactive compounds that can be used as antidiabetics. This study aims to identify bioactive compounds of ethanol extract of takokak fruit and antidiabetic test of n-Hexane fraction. The method used to obtain the extract is maceration using ethanol . Antidiabetic testing is carried out through in vivo testing with the Oral Glucose Tolerance Test (OGTT) method on white rats. Secondary metabolites are compounds contained in taakokak fruit that are identified as flavonoids, saponins, tannins, steroids and terpenoids . The results of the antidiabetic test showed that the n-H

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43

Suardiana, I. Kadek, Dwi Endarti, and Tuangrat Phodha. "Cost-effectiveness analysis of Oral Semaglutide treatment for type 2 diabetes mellitus patients: a systematic review." Journal of Public Health and Development 22, no. 3 (2024): 272–88. http://dx.doi.org/10.55131/jphd/2024/220322.

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GLP-1 is a new generation of antidiabetics recommended by the American Diabetes Association and European Association for the study of diabetes as an add-on therapy for metformin when therapeutic purposes are not achieved. In this context, oral Semaglutide received FDA approval in September 2019 to be used alongside dietary and exercise regimens to enhance glycemic management in adults diagnosed with type 2 diabetes mellitus (T2DM). Therefore, this systematic review aimed to analyze cost-effectiveness of oral Semaglutide compared to other antidiabetics and/or injectable GLP-1 within the same gr

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44

Mogali, Sahana M., Aruna Bhushan, and Jagadishchandra S. Ratnakar. "Drug utilization study and adverse drug reactions of oral anti diabetics among type 2 diabetes mellitus patients in tertiary care hospital." International Journal of Basic & Clinical Pharmacology 8, no. 4 (2019): 700. http://dx.doi.org/10.18203/2319-2003.ijbcp20191103.

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Background: The aim was to evaluate the drug utilization pattern of oral antidiabetic drugs in type 2 diabetes mellitus outpatients and monitor adverse drug reactions (ADRs) associated with oral antidiabetic drugs.Methods: A retrospective observational study was carried out by collecting the data of type 2 diabetes mellitus patients visiting outpatient department of noncommunicable disease clinic of a tertiary care hospital for a period of one year. The data of demographic, drug utilization pattern and adverse drug reactions of patients on oral antidiabetic drugs was collected and entered in a

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45

Trevisan, Danilo Donizetti, Thaís Moreira São-João, Marília Estevam Cornélio, Maria Rui Miranda Grilo Correia de Sousa, Roberta Cunha Matheus Rodrigues, and Maria Helena de Melo Lima. "Action and coping plans related to the behavior of adherence to oral anti-diabetic medication." Medicina (Ribeirão Preto) 54, no. 1 (2021): e172558. http://dx.doi.org/10.11606/issn.2176-7262.rmrp.2021.172558.

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Study Design: Study Design: This mixed-methods study. Objective: To describe action plans related to the behavior of adherence to oral antidiabetic medications produced by people with type 2 diabetes mellitus and identify the challenges and coping strategies for the establishment of this behavior. Methods: The study followed-up 44 people with type 2 diabetes mellitus who used oral antidiabetic medications from southeast Brazil. Adults were invited to build action and coping plans based on the Implementation Intention Theory. The plans were quantitative and qualitatively analyzed. Results: Acti

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46

Muntean, Andrei Cătălin, Claudiu Morgovan, Smaranda Cosma, et al. "STUDY OF LIFE QUALITY AND TREATMENT SATISFACTION OF ROMANIAN DIABETIC PATIENTS." CBU International Conference Proceedings 7 (September 30, 2019): 771–77. http://dx.doi.org/10.12955/cbup.v7.1453.

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In Romania, antidiabetic medication is free, based on a program of the Ministry of Public Health: “Treatment of patients with diabetes mellitus”. Since October 1, 2006, antidiabetic drugs have been delivered through open circuit pharmacies in contractual relationship with the National Health Insurance House, after four years of centralized delivery through hospital pharmacies. Objectives: This study aims to describe the influences of the diabetes treatment regarding patients’ quality of life and their satisfaction. Methods: A cross-sectional descriptive study was performed in pharm

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47

Özyardımcı Ersoy, Canan. "Oral antidiabetic treatment approaches in type 2 diabetes mellitus." Turkiye Aile Hekimligi Dergisi 14, no. 1 (2010): 1–7. http://dx.doi.org/10.2399/tahd.10.001.

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48

Giampietro, Beatrice, Fabrizio Tiratterra, Antonella Paradiso, Fabiana Lanti, Chiara Villani, and Umberto Recine. "Quality of diabetes mellitus therapy in patients with chronic kidney disease in the real world." Italian Journal of Medicine 11, no. 1 (2017): 48. http://dx.doi.org/10.4081/itjm.2017.726.

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Chronic kidney disease (CKD) is very often among diabetic patients. Some oral antidiabetic agents are not recommended in the presence of CKD. Aim of the study was to evaluate the quality of diabetes mellitus (DM) treatment in nephrophatic patients in the real world. A total of 265 subjects with type 2 DM, consecutively admitted to the internal medicine departments of two hospitals in Rome, were recruited. Patients hospitalized for hypoglycemia, decompensated DM, acute kidney failure or worsening nephropathy were excluded. For each patient, the following data were collected: age, gender, estima

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49

Bressler, Rubin, and David G. Johnson. "Oral Antidiabetic Drug Use in the Elderly." Drugs & Aging 9, no. 6 (1996): 418–37. http://dx.doi.org/10.2165/00002512-199609060-00005.

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50

Krentz, Andrew J., Robin E. Ferner, and Clifford J. Bailey. "Comparative Tolerability Profiles of Oral Antidiabetic Agents." Drug Safety 11, no. 4 (1994): 223–41. http://dx.doi.org/10.2165/00002018-199411040-00002.

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