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Dissertations / Theses on the topic 'Oral biopsy'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Maurer, Katja. "Oral brush biopsy analysis by MALDI-ToF Mass Spectrometry for early cancer diagnosis." Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-116691.

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Objectives: Intact cell peptidome profiling (ICPP) with MALDI-ToF Mass-Spectrometry holds promise as a non invasive method to detect head and neck squamous cell carcinoma (HNSCC) objectively, which may improve the early diagnosis of oral cancer tremendously. The present study was designed to discriminate between tumour samples and non-cancer controls (healthy mucosa and oral lesions) by analysing complete spectral patterns of intact cells using MALDI-ToF MS. Material and Methods: In the first step, a data base consisting of 26 patients suffering from HNSCC was established by taking brush biop

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2

Harrington, Christine. "The Prevalence of Pseudoxanthoma Elasticum-like Connective Tissue Changes in an Oral Biopsy Service." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308062343.

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3

Afrogheh, Amir. "An evaluation of Shandon Papspin liquid based oral test utilizing a novel cytologic scoring system." Thesis, University of the Western Cape, 2010. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_4355_1360592750.

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<p>Background and Aims: While a single &ldquo<br>high quality&rdquo<br>oral liquid based cytology (LBC) study has shown a high sensitivity and specificity for the technique in detection of oral dysplasia and malignancy, the high unit cost of this technology cannot be borne by the developing African countries. This study aims to evaluate the efficiency of an alternative cost-effective technique, Shandon PapSpin (PS) LBC in&nbsp<br>diagnosis of oral and oropharyngeal dysplasia and malignancy. Materials and Methods.We compared the diagnostic accuracy of Shandon PS LBC with that of scalpel biopsy

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4

Mazarro, Campos Alejandro. "Relevancia de los ganglios centinela en territorios atípicos en el tratamiento del carcinoma escamoso de cavidad oral en fase T1-2N0." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/671264.

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Introducció: El tractament d'elecció del carcinoma escamós de cavitat oral en estadis inicials (T1-2N0) es basa en la resecció quirúrgica del tumor primari, acceptant-se tres opcions per al tractament del coll clínicament negatiu: l'observació clínica, el buidament ganglionar cervical i la biòpsia del gangli sentinella. L'aplicació de la biòpsia del gangli sentinella en el territori cervicofacial es basa en l'elevada seqüencialització del flux limfàtic local, havent-se evidenciat a més patrons de drenatge específics per a cada localització tumoral. No obstant això, els estudis prequirúrg

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Liu, Muyuan, Steven J. Wang, Xihong Yang, and Hanwei Peng. "Diagnostic Efficacy of Sentinel Lymph Node Biopsy in Early Oral Squamous Cell Carcinoma: A Meta-Analysis of 66 Studies." PUBLIC LIBRARY SCIENCE, 2017. http://hdl.handle.net/10150/622744.

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Objectives The diagnostic efficacy of sentinel lymph node biopsy(SLNB) in early oral squamous cell carcinoma(OSCC) still remains controversial. This meta-analysis was conducted to assess the diagnostic value of SLNB in clinically neck-negative T1-2 OSCC. Methods A systematic literature search for relevant literature published up to September 11, 2016 was conducted in PubMed, Embase, Web of Science, Cochrane Library and ClinicalTrials, and the reference lists of eligible studies were examined. Data from different studies were pooled to estimate the summary sentinel lymph node(SLN) identificatio

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6

Santos, Ana Paula Candido dos. "Análise comparativa da punção aspirativa por agulha fina (PAAF) em relação a biópsia em cavidade oral e região de cabeça e pescoço." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/23/23139/tde-22122010-145536/.

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O presente estudo teve como objetivos avaliar a sensibilidade, a especificidade e a acurácia da Punção Aspirativa por Agulha Fina (PAAF) em nódulos submucosos da cavidade bucal e da região de cabeça e pescoço como ferramenta auxiliar de diagnóstico. Foram selecionados 50 pacientes consecutivamente que procuraram a Clínica da Disciplina de Estomatologia Clínica da FOUSP, portadores de lesões em boca e em região de cabeça e pescoço. O material obtido pela PAAF foi enviado a um mesmo patologista apenas com o diagnóstico clínico e após a emissão do laudo da PAAF o laudo do anátomo patológico era e

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7

Bozyk, Natalie. "The clinical utility of salivary exosomes as biomarkers in oral squamous cell carcinoma." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/211455/1/Natalie_Bozyk_Thesis.pdf.

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The project was a step forward in a new area of translational medicine – liquid biopsy - and its diagnostic potential in oral squamous cell carcinoma. A panel of protein markers was identified from isolated salivary exosomes, which was able to discriminate between cancer-free healthy controls, at-risk patients with oral pre-malignant disorder, and early-stage oral squamous cell carcinoma patients. Saliva collection methods were also investigated, with the unstimulated ‘drool’ method being the most effective method for yielding exosomes of high quality and quantity.

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8

Maurer, Katja [Verfasser], Torsten W. [Akademischer Betreuer] Remmerbach, Klaus [Akademischer Betreuer] Eschrich, Rainer [Gutachter] Haak, and Andrea-Maria [Gutachter] Schmidt-Westhausen. "Oral brush biopsy analysis by MALDI-ToF Mass Spectrometry for early cancer diagnosis / Katja Maurer ; Gutachter: Rainer Haak, Andrea-Maria Schmidt-Westhausen ; Torsten W. Remmerbach, Klaus Eschrich." Leipzig : Universitätsbibliothek Leipzig, 2013. http://d-nb.info/1238367585/34.

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9

Sousa, Hildecazio de Oliveira. "Estudo clinicopatológico de biópsias bucais em crianças e idosos: um estudo de 57 anos." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/5841.

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Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2016-08-04T17:50:33Z No. of bitstreams: 2 Dissertação- Hidecazio de Oliveira Souza - 2016.pdf: 2011905 bytes, checksum: 80960a24ceef92045a0a71ba9a6cff7d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-08-05T13:37:40Z (GMT) No. of bitstreams: 2 Dissertação- Hidecazio de Oliveira Souza - 2016.pdf: 2011905 bytes, checksum: 80960a24ceef92045a0a71ba9a6cff7d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD

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10

Chnee, Lúcia Helena. ""Avaliação do tratamento hormonal e/ou intervencionista por punção nos tumores císticos de ovários"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-17102006-141120/.

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Objetivo: O objetivo deste estudo foi avaliar em mulheres com tumores císticos de ovário, a proporção que, somente com o tratamento clínico e/ou punção, não necessitaram de cirurgia; a influência da medicação e das doenças associadas na indicação de cirurgia e se a punção reduziu significativamente o tamanho dos cistos. Casuística e métodos: Selecionaram-se 71 mulheres com idade entre 19 e 70 anos de idade, portadoras de tumores císticos de ovário maior que 5 cm, com características de benignidade ao ultra-som transvaginal com Doppler colorido e pulsado e com perfil endócrino e marcadores séri

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11

Manzano, Afonso Celso de Moraes. "Caracterização imuno-histoquimica do infiltrado linfocitario em biopsia de carcinoma espinocelular da lingua e soalho oral e sua implicação prognostica." [s.n.], 2001. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313794.

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Orientadores : Alfio Jose Tincani, Albina Messias de Almeida Milani Altemani<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-07-29T01:19:50Z (GMT). No. of bitstreams: 1 Manzano_AfonsoCelsodeMoraes_M.pdf: 18156904 bytes, checksum: 82ab73e32474169bc68cb4015ab02e9b (MD5) Previous issue date: 2001<br>Resumo: o infiltrado inflamatório tem sido considerado como um possível fator prognóstico em neoplasias malignas. O objetivo do presente estudo é caracterizar pela técnica imuno-histoquímica, o infiltrado inflamatório l

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12

Podkówka, Lucyna. "Wartość pokarmowa oraz ocena przydatności do zakiszania zielonek z Phleum pratense, Lolium perenne i Festulolium." Rozprawa doktorska, [Nakł.aut.], 2001. http://dlibra.utp.edu.pl/Content/270.

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13

Skowron, Karolina Jadwiga. "Mikrobiologiczna ocena procesu kompostowania biomasy uzyskanej w procesie kofermentacji osadów ściekowych i odpadowych tłuszczów rybnych oraz wpływ powstałego kompostu na wybrane mikroorganizmy glebowe." Rozprawa doktorska, Uniwersytet Technologiczno-Przyrodniczy w Bydgoszczy, 2014. http://dlibra.utp.edu.pl/Content/694.

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Celem pracy było sprawdzenie skuteczności higienizacji procesu pryzmowego kompostowania osadów ściekowych poddanych uprzednio kofermentacji z dodatkiem odpadowych tłuszczów rybnych w oparciu o kinetykę inaktywacji wybranych drobnoustrojów wskaźnikowych oraz ocena wpływu kompostu na wybrane grupy mikroorganizmów glebowych i morfometrię roślin (gorczyca biała, Sinapis alba var.Radena)

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14

Corrêa, Maria Elvira Pizzigatti. "A mucosa oral e glandulas salivares acessorias na doença do enxerto contra o hospedeiro cronica pos transplante de medula ossea : estudo prospectivo dos primeiros 63 transplantes de medula ossea : analise comparativa com parametros clinicos e biopsia de pele Hemocentro/Unicamp." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311043.

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Orientadores: Maria Leticia Cintra, Konradin Metze<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-07-25T11:19:25Z (GMT). No. of bitstreams: 1 Correa_MariaElviraPizzigatti_M.pdf: 8885078 bytes, checksum: 7071dad04af31ca5115d4fa9aed74398 (MD5) Previous issue date: 1999<br>Resumo: A Doença do Enxerto contra o Hospedeiro representa uns dos fatores de maior morbidade e mortalidade pós transplante alogênico de medula óssea (TMO). Lesões na cavidade bucal e em glândulas salivares menores são achados comuns na GVHDc, m

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15

Maurer, Katja. "Oral brush biopsy analysis by MALDI-ToF Mass Spectrometry for early cancer diagnosis." Doctoral thesis, 2012. https://ul.qucosa.de/id/qucosa%3A11998.

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Objectives: Intact cell peptidome profiling (ICPP) with MALDI-ToF Mass-Spectrometry holds promise as a non invasive method to detect head and neck squamous cell carcinoma (HNSCC) objectively, which may improve the early diagnosis of oral cancer tremendously. The present study was designed to discriminate between tumour samples and non-cancer controls (healthy mucosa and oral lesions) by analysing complete spectral patterns of intact cells using MALDI-ToF MS. Material and Methods: In the first step, a data base consisting of 26 patients suffering from HNSCC was established by taking brush biop

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16

Krishnan, Sabapathy Giridhar Suren. "Innovating surgery for oral squamous cell carcinoma with targeted fluorescent and magnetic tracers." Thesis, 2022. https://hdl.handle.net/2440/135953.

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Oral squamous cell carcinoma (OSCC) is characterised by its locally aggressive nature and its high propensity to metastasise to regional lymph nodes (LN)s. It is well-established that margin status and the presence of LN metastases are two of the most important factors affecting prognosis. While patient and tumour factors cannot be changed after presentation, margin control during primary tumour resection and staging of the clinically occult neck are two components of treatment that are within the control of the head and neck surgeon. Despite this, positive margin rates have not improved over

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17

Weber, Michaela. "Massenspektrometrische Untersuchungen an Präparaten oraler Bürstenbiopsien bei potenziell malignen Veränderungen der Mundschleimhaut." 2018. https://ul.qucosa.de/id/qucosa%3A34113.

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Das Plattenepithelkarzinom stellt mit über 90% die häufigste maligne Neubildung innerhalb der Mundhöhle mit gravierenden funktionellen Einschränkungen für die betroffenen Patienten und hoher Mortalität dar. In den meisten Fällen bestehen bereits vor der malignen Transformation visuell erkennbare Veränderungen mit höherem Entartungspotential, sogenannte potenziell maligne Veränderungen. Die vorliegende Arbeit beschäftigt sich mit einem experimentellen Verfahren zur oralen Tumorfrüherkennung und Dignitätsabklärung von potenziell malignen Veränderungen der Mundschleimhaut. Grundlage bildet das V

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18

Deuerling, Lena. "Evaluation of the Accuracy of Liquid-Based Oral Brush Cytology in Screening for Oral Squamous Cell Carcinoma." 2020. https://ul.qucosa.de/id/qucosa%3A72207.

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Das orale Plattenepithelkarzinom ist der weltweit häufigste Tumor der Mundhöhle und des Rachens. Das Ziel dieser retrospektiven Studie war die Evaluation der Treffsicherheit der flüssigkeitsbasierten oralen Bürstenbiopsie als Screening-Methode für das orale Plattenepithelkarzinom. Bei der Bürstenbiopsie handelt es sich um ein Verfahren, das ursprünglich aus der Gynäkologie kommt und dort schon seit Jahrzehnten erfolgreich als Abstrich-Methode eingesetzt wird. Die orale Bürstenbiopsie dient der Gewinnung von Zellen aus klinisch suspekten Läsionen der Mundhöhle, in dieser Studie unter Verwendung

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19

Cardoso, Richard Michalsky. "A importância da saliva como biópsia líquida no cancro oral." Master's thesis, 2019. http://hdl.handle.net/10284/9085.

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O presente trabalho consta em uma revisão bibliográfica que tem como objetivo principal analisar a importância da saliva como material para biópsias líquidas e a sua relação com a possível deteção precoce e controle do cancro, afim de buscar tratamentos mais rápidos e terapêuticas mais eficazes. As biópsias líquidas e a saliva são uma combinação altamente harmoniosa, pois por apresentarem diversas vantagens, e a saliva, por ser um material de fácil acesso e não invasivo, têm vindo a ser descritas de forma crescente para deteção de diferentes tipos de neoplasias, e entre elas, o cancro oral. O

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20

ROJAS, MARIANA ANDREA. "Positional differences in the gene expression profile of human alveolar mucosa, buccal attached gingiva and palatal tissue-derived fibroblasts in the early phases of wound healing and the role of chlorhexidine digluconate and hyaluronic acid as modifiers of oral gingival-derived cells behaviour. A clinical, histological, immunohistochemical and biomolecular analysis." Doctoral thesis, 2022. http://hdl.handle.net/11573/1613507.

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Wound healing is a complex process orchestrated by a variety of known and unknown factors. Oral wound healing presents peculiar characteristics as accelerated wound closure and reduced scar formation when compared with cutaneous wound repair, and it has been recognized the key role of fibroblasts in this concern. In fact, oral-derived fibroblasts represent a resource of great interest for regenerative approaches due to their self-renewal capacity and plasticity. The biomolecular basis of the differences between oral and skin repair have been described by several studies, showing the main diff

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21

Skala, Melissa Caroline. "Multiphoton microscopy, fluorescence lifetime imaging and optical spectroscopy for the diagnosis of neoplasia." Diss., 2007. http://dukespace.lib.duke.edu/dspace/bitstream/10161/182/1/D_Skala_Melissa_a_052007.pdf.

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22

Pardo, Alessia, Annarita Signoriello, Caterina Signoretto, et al. "CARATTERIZZAZIONE DEL MICROBIOTA ORALE E DI BIOPSIE DI TESSUTO VALVOLARE PATOLOGICO IN UN CAMPIONE DI PAZIENTI PARODONTALI E NON PARODONTALI." Doctoral thesis, 2021. http://hdl.handle.net/11562/1044989.

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Aim. To assess the prevalence of periodontal disease among patients presenting severe heart valve impairment and requiring coronary by-pass surgery. To investigate the presence of periodontal pathogens in cardiovascular specimens and to analyse the relationship between oral and cardiovascular patterns of the microorganisms detected. Materials and Methods. An observational study was conducted at the Cardiovascular Surgery Division, University Hospital of Verona, Verona, Italy. The Ethical approval was previously obtained in order to enroll subjects referring to the Hospital for heart valves rep

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