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Journal articles on the topic 'Oral Candidiasis'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 January 2023

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1

Marroquín-Remón, Rosmin, and Patricia Chang. "Candidiasis oral." Revista médica (Colegio de Médicos y Cirujanos de Guatemala) 160, no. 3 (December 8, 2021): 333–36. http://dx.doi.org/10.36109/rmg.v160i3.370.

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A continuación, se presenta el caso de un paciente masculino de 20 años de edad con diagnóstico de candidiasis oral. Antecedentes de enfermedad renal crónica KDOQI V, trasplante renal con disfunción de injerto de 2 años, actualmente en hemodiálisis, linfoma de células grandes tipo B

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2

Dellinger, Tracy M., and H. Mark Livingston. "Oral Candidiasis." Annals of Pharmacotherapy 37, no. 10 (October 2003): 1529. http://dx.doi.org/10.1345/aph.1d125.

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3

Ray, Thomas L. "Oral Candidiasis." Dermatologic Clinics 5, no. 4 (October 1987): 651–62. http://dx.doi.org/10.1016/s0733-8635(18)30708-3.

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4

Peterson, Douglas E. "Oral Candidiasis." Clinics in Geriatric Medicine 8, no. 3 (August 1992): 513–28. http://dx.doi.org/10.1016/s0749-0690(18)30461-0.

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5

Millsop, Jillian W., and Nasim Fazel. "Oral candidiasis." Clinics in Dermatology 34, no. 4 (July 2016): 487–94. http://dx.doi.org/10.1016/j.clindermatol.2016.02.022.

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6

Akpan, A. "Oral candidiasis." Postgraduate Medical Journal 78, no. 922 (August 1, 2002): 455–59. http://dx.doi.org/10.1136/pmj.78.922.455.

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7

Lynch, Denis P. "Oral candidiasis." Oral Surgery, Oral Medicine, Oral Pathology 78, no. 2 (August 1994): 189–93. http://dx.doi.org/10.1016/0030-4220(94)90146-5.

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8

Ravić-Nikolić, Ana. "Oral candidiasis." Galenika Medical Journal 1, no. 4 (2022): 48–52. http://dx.doi.org/10.5937/galmed2204050r.

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Oral candidiasis is an opportunistic fungal infection of the oral cavity, most often caused by Candida albicans. It is common in infants and the elderly. It is mostly asymptomatic in healthy adults. Predisposing factors that contribute to the occurrence of oral candidiasis can be local and systemic, and the clinical course can be acute and chronic. Application of local therapy is sufficient in the majority of cases, but in resistant cases systemic anti-fungal therapy must be commenced, especially in persons with a compromised immune response. Prevention of oral candidiasis is very important - it implies education of the general population about their habits, such as alcohol consumption and smoking, regularly brushing teeth with toothpaste and using antiseptics for rinsing the oral cavity, maintaining the hygiene of dental prostheses, and regular visits to the dentist. In cases where the changes persist despite all the treatment measures taken, it is necessary to rule out malignancies of the oral cavity and conditions of severe acquired immunodeficiency.

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9

Limbhore, Mayur Vilas, Shandilya Ramanojam, Pallavi Rathi, Vikrant Sane, and Adil Mevawala. "ORAL CANDIDIASIS: AN OVERVIEW AND CASE REPORT." Era's Journal of Medical Research 6, no. 2 (December 2019): 160–66. http://dx.doi.org/10.24041/ejmr2019.147.

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10

Kim, Chorok, and Jihyun Song. "Association between Candidiasis and Early Childhood Caries : Analysis Using Healthcare Big Data." JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY 47, no. 4 (November 30, 2020): 359–67. http://dx.doi.org/10.5933/jkapd.2020.47.4.359.

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The aim of this study was to identify the association between candidiasis and early childhood caries and to investigate whether the experience of candidiasis or oral candidiasis before age 1 can be considered as a risk factor for early childhood caries.<br/>The database used in this study was provided by Health Insurance Review and Assessment Service. Medical records of children born from January 2010 to December 2012 were obtained, and those without dental records were excluded. Subjects were divided into several groups based on the experience of candidiasis or oral candidiasis before age 6: candidiasis group and non-candidiasis group; oral candidiasis group and non-oral candidiasis group. Another categorization was done according to the experience of candidiasis or oral candidiasis before age 1. The incidence rate of early childhood caries in each group were compared.<br/>The prevalence of dental caries in children who have been diagnosed with candidiasis or oral candidiasis before age 6 was significantly different from those who have not experienced candidiasis. Similarly, children who have suffered from candidiasis or oral candidiasis before age 1 had significantly different incidence of caries from the children without candidiasis experience.

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11

Sabila, Addina Aimana, Ade Ismail A.K, and Rochman Mujayanto. "ORAL HYGIENE BURUK PASIEN RAWAT INAP TIDAK BERKAITAN DENGAN PERTUMBUHAN ORAL CANDIDIASIS." ODONTO : Dental Journal 4, no. 1 (August 9, 2017): 56. http://dx.doi.org/10.30659/odj.4.1.56-60.

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Background: Nosocomial infections can develop in the oral cavity due to poor oral hygiene. Oral Candidiasis is one of the most frequent nosocomial infection in oral cavity. The objective of this study is to describe the oral hygiene and oral candidiasis in hospitalized patients. Method: This analitical observational study used cross sectional design. Subject of the study were 74 adult patients aged 20-65 who are hospitalized at the Sultan Agung Islamic Hospital Semarang. Oral hygiene assessed from the presence of debris and calculus on the tooth surface using Simplified Oral Hygiene Index (OHIS) that were grouped in three categories (good, moderate, bad). Oral candidiasis diagnosed through clinical examination and swab procedure of suspicious lesions, and identified the presence of its spores and hyphae under a microscope observation. Kendal Tau test is used to analyze the correlation between oral hygiene with oral candidiasis. Results: Results showed patients with oral candidiasis in the poor and moderate oral hygiene were 29.7% and 1.4%, whereas patients without oral candidiasis in the poor and moderate oral hygiene were 60.8% and 8.1%. Kendall Tau correlation test results p value of 0.235 (p> 0.05). Conclusion: Conclusion of this study showed there is no association between oral hygiene with oral candidiasis.

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12

Chandan, J. S., R. S. Randhawa, and T. Thomas. "Oral health: Asthma and oral candidiasis." British Dental Journal 223, no. 9 (November 2017): 621. http://dx.doi.org/10.1038/sj.bdj.2017.939.

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13

Agrawal, Ashutosh, Arun Singh, Renuka Verma, and Aditi Murari. "Oral candidiasis: An overview." Journal of Oral and Maxillofacial Pathology 18, no. 4 (2014): 81. http://dx.doi.org/10.4103/0973-029x.141325.

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14

Dineshshankar, Janardhanam, Muniapillai Sivakumar, M. Karthikeyan, P. Udayakumar, KT Shanmugam, and G. Kesavan. "Immunology of oral candidiasis." Journal of Pharmacy and Bioallied Sciences 6, no. 5 (2014): 9. http://dx.doi.org/10.4103/0975-7406.137251.

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15

Epstein, Joel B. "Oral and pharyngeal candidiasis." Postgraduate Medicine 85, no. 5 (April 1989): 257–69. http://dx.doi.org/10.1080/00325481.1989.11700671.

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16

Tjioe, K. C. "Diagnosing hyperplastic oral candidiasis." QJM 105, no. 9 (June 30, 2012): 921. http://dx.doi.org/10.1093/qjmed/hcs124.

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17

Chaudhry, Anand P., Abraham Chachoua, Brian R. Saltzman, and Alvin Friedman-Kien. "Oral candidiasis and AIDS." Journal of the American Dental Association 116, no. 7 (June 1988): 818–20. http://dx.doi.org/10.14219/jada.archive.1988.0283.

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18

Jeganathan, S., and Yow Cheong Chan. "Immunodiagnosis in oral candidiasis." Oral Surgery, Oral Medicine, Oral Pathology 74, no. 4 (October 1992): 451–54. http://dx.doi.org/10.1016/0030-4220(92)90293-y.

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19

Skakodub, A. A., N. A. Geppe, O. I. Admakin, Ad A. Mamedov, S. N. Chebysheva, and O. V. Dudnik. "Candida-associated stomatitis in children with rheumatic diseases." Voprosy praktičeskoj pediatrii 16, no. 2 (2021): 55–60. http://dx.doi.org/10.20953/1817-7646-2021-2-55-60.

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Objective. To improve diagnostics and treatment of candidiasis in children with rheumatic diseases. Patients and methods. We performed clinical examination of the oral cavity in 316 children with rheumatic diseases and assessed the frequency and clinical manifestations of oral candidiasis in them. Oral swabs were taken from patients with any complaints or clinical symptoms of candidiasis. Conclusion. We have developed and implemented an algorithm of treatment of oral candidiasis in children with rheumatic diseases, depending on the form of candidiasis, course of the main disease, and basic therapy used. Key words: oral candidiasis, rheumatic diseases, children

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20

Darwazeh, Azmi M. G., and Tamer A. Darwazeh. "What Makes Oral Candidiasis Recurrent Infection? A Clinical View." Journal of Mycology 2014 (December 28, 2014): 1–5. http://dx.doi.org/10.1155/2014/758394.

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Clinical oral Candida infection (candidiasis) is one of the common oral mucosal infections, and its management is usually frustrating due to either treatment failure or recurrence. Historically, oral candidiasis has been branded as disease of diseased. The unsuccessful management of oral candidiasis can due to either incorrect diagnosis, failure to identify (or correct) the underlying predisposing factor(s), or inaccurate prescription of antifungal agents. Failure to properly treat oral candidiasis will lead to persistence of the fungal cell in the oral cavity and hence recurrence of infection. The oral health care provider should be aware of these fall pits in order to successfully manage oral candidiasis.

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21

Funieru, Cristian, Carmen Gheorghe, Ioanina Părlătescu, and Şerban Ţovaru. "Oral candidiasis – A complication of dry mouth." Romanian Journal of Stomatology 63, no. 1 (March 31, 2017): 38–42. http://dx.doi.org/10.37897/rjs.2017.1.7.

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Introduction. Oral candidiasis is a complication of dry mouth witch is not present in all cases, but its prevalence remains high. Material and method. 29 patients aged 45 to 82 years suffering from dry mouth caused by various general conditions were selected for this study. Clinical examinations were performed and all the lesions of oral mucosa were counted. The accurate diagnosis of oral candidiasis was established by the mycological exam. Results. 66% of patients involved in this study presented oral candidiasis confirmed by the laboratory. The atrophic and hyperplasic oral candidiasis were the most common clinical types found in this study. Conclusions. The prevalence of oral candidiasis remains relatively high among patients suffering from dry mouth; therefore dentists should treat or guide them to a specialist.

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22

Yamazaki, T., R. Ushikoshi-Nakayama, K. Shirone, M. Suzuki, S. Abe, N. Matsumoto, H. Inoue, and I. Saito. "Evaluation of the effect of a heat-killed lactic acid bacterium, Enterococcus faecalis 2001, on oral candidiasis." Beneficial Microbes 10, no. 6 (July 10, 2019): 661–69. http://dx.doi.org/10.3920/bm2018.0115.

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The effect of a preparation of heat-killed Gram-positive lactic acid bacteria Enterococcus faecalis 2001 (EF-2001) on oral candidiasis was evaluated by two studies. An in vitro study was performed to assess the inhibitory effect on mycelial growth of Candida strains isolated from a patient with oral candidiasis, and a clinical study was done in patients with oral candidiasis. In the in vitro study, EF-2001 inhibited mycelial growth of IT-1, a Candida strain isolated from a patient with oral candidiasis, at concentrations ≥2.34×109 cells/ml. An open clinical study was performed in 13 patients with oral candidiasis. The subjects took a powder containing 7.5×1011 heat-killed EF-2001 once a day before bedtime for seven consecutive days. In 11 of the 12 patients available for analysis (92%), the oral Candida load (cfu/swab) showed a significant decrease (P=0.01079, d=-0.437). There was a 55% decrease of Candida albicans and a 93.8% decrease of Candida glabrata. The following symptoms showed significant improvement: tinnitus (P=0.048, d=-0.462), cold feeling (P=0.048, d=-0.463), and depression (P=0.019, d=-0.34). In addition, 4 out of 26 oral symptoms tended to improve. These results suggest that EF-2001 significantly decreased the oral Candida load in patients with oral candidiasis by inhibiting mycelial growth and that EF-2001 is an effective treatment for oral candidiasis.

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23

Olivas-Escárcega, Victoria, Ma del Socorro Ruiz-Rodríguez, Ma del Pilar Fonseca-Leal, Miguel Ángel Santos-Díaz, Antonio Gordillo-Moscoso, Juan Francisco Hernández-Sierra, and Amaury de Pozos-Guillén. "Prevalence of Oral Candidiasis in Chronic Renal Failure and Renal Transplant Pediatric Patients." Journal of Clinical Pediatric Dentistry 32, no. 4 (July 1, 2008): 313–17. http://dx.doi.org/10.17796/jcpd.32.4.f53343t742150l73.

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The objective of this study was to evaluate the prevalence and risk factors associated with candidiasis in chronic renal failure (CRF) and renal transplant (RT) patients. A cross-sectional study was made of 66 patients who were divided into 2 groups: group A (33 patients), RT patients, and group B (33 patients), who had been diagnosed with CRF. Data with respect to demographics, treatment type and duration, clinical laboratory results for blood leucocytes, oral hygiene, and diagnosis of oral candidiasis were collected. Risk factors associated with candidiasis were evaluated. Among the 66 patients, 21 showed microbiologic evidence of oral candidiasis; 12 of these were from the RT group and 9 were from the CRF patients. Children who were renally compromised (RT and CRF) presented a frequency of oral candidiasis of 31.82%, with no difference between study groups. C. albicans was the most frequently isolated species from RT and CRF patients. Duration of therapy and oral hygiene were the variables associated with the presence of oral candidiasis.

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24

Gallottini Magalhães, Marina, Daniela Franco Bueno, Edna Serra, and Rhoner Gonçalves. "Oral manifestations of HIV positive children." Journal of Clinical Pediatric Dentistry 25, no. 2 (January 1, 2002): 103–6. http://dx.doi.org/10.17796/jcpd.25.2.f01k062j7315660v.

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Oral manifestations in HIV positive children were observed in thirty-eight HIV infected children that have received care at the Special Care Dentistry Center (SCDC) of the School of Dentistry, University of Sao Paulo. Results have shown that 52.63% of the children presented at least one oral manifestation related with HIV/AIDS. Angular cheilitis occurred in 28.94%, parotid gland bilateral enlargement, pseudomembranous candidiasis and erythematous candidiais in 18.42%, conventional gingivitis in 13.15%, herpes simplex in 5.26%, hairy leukoplakia, recurrent aphtous ulcer and condyloma acuminatum in 2.63%. Although enamel hypoplasia occurred in 23.68%, this could not be attributed specifically to HIV infection.

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25

DROBOTKO, L. N., L. P. KISELNIKOVA, A. G. SEDOYKIN, and I. A. DRONOV. "FUNGAL DISEASE OF THE ORAL CAVITY." Medical Council, no. 9 (July 18, 2017): 38–42. http://dx.doi.org/10.21518/2079-701x-2017-9-38-42.

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The problem of oral candidiasis is topical for the adult population and children due to frequent recurrence, the presence of a large number of predisposing factors, lack of compliance with hygienic measures for the care of the oral cavity. The most common causative agent of oral candidiasis is the fungi C. albicans. The article discusses the risk factors for the development of this disease taking into account age-related factors, provides clinical morphological characteristics of acute and chronic forms of oral candidiasis. Local causal treatment of isolated candidal lesions of the oral cavity by 1% solution of clotrimazole (Candid) is effective both in children and adults. Preventive care after the course etiotropic therapy are aimed at reducing the number of relapses of oral candidiasis.

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26

Diaz, Patricia, Bo-Young Hong, Amanda Dupuy, Linda Choquette, Angela Thompson, Andrew Salner, Peter Schauer, et al. "Integrated Analysis of Clinical and Microbiome Risk Factors Associated with the Development of Oral Candidiasis during Cancer Chemotherapy." Journal of Fungi 5, no. 2 (June 13, 2019): 49. http://dx.doi.org/10.3390/jof5020049.

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Oral candidiasis is a common side effect of cancer chemotherapy. To better understand predisposing factors, we followed forty-five subjects who received 5-fluorouracil- or doxorubicin-based treatment, during one chemotherapy cycle. Subjects were evaluated at baseline, prior to the first infusion, and at three additional visits within a two-week window. We assessed the demographic, medical and oral health parameters, neutrophil surveillance, and characterized the salivary bacteriome and mycobiome communities through amplicon high throughput sequencing. Twenty percent of all subjects developed oral candidiasis. Using multivariate statistics, we identified smoking, amount of dental plaque, low bacteriome and mycobiome alpha-diversity, and the proportions of specific bacterial and fungal taxa as baseline predictors of oral candidiasis development during the treatment cycle. All subjects who developed oral candidiasis had baseline microbiome communities dominated by Candida and enriched in aciduric bacteria. Longitudinally, oral candidiasis was associated with a decrease in salivary flow prior to lesion development, and occurred simultaneously or before oral mucositis. Candidiasis was also longitudinally associated with a decrease in peripheral neutrophils but increased the neutrophil killing capacity of Candida albicans. Oral candidiasis was not found to be associated with mycobiome structure shifts during the cycle but was the result of an increase in Candida load, with C. albicans and Candida dubliniensis being the most abundant species comprising the salivary mycobiome of the affected subjects. In conclusion, we identified a set of clinical and microbiome baseline factors associated with susceptibility to oral candidiasis, which might be useful tools in identifying at risk individuals, prior to chemotherapy.

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27

Rahman, M. Hasibur, Md Hadiuzzaman, Nahida Islam, Md Shahidul Islam, Sabrina Alam Mumu, and Atia Sharmin. "Oral candidiasis - Perleche Mimicking Malignancy." Community Based Medical Journal 3, no. 1 (February 10, 2014): 53–55. http://dx.doi.org/10.3329/cbmj.v3i1.53330.

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Candida species inhabit the mucosal surfaces of healthy individuals. Major forms of oral candidiasis are pseudomembranous and atrophic form, but chronic hyperplastic candidiasis (CHC) is rarely seen. We encountered a case of whitish plaque with nodule and ulceration. When an intraoral nodule is observed, the possibility of CHC should be taken into consideration. Biopsy of the lesion failed to show any signs of malignancy, and patient responded well to oral fluconazole therapy only. CBMJ 2014 January: Vol. 03 No. 01 P: 53-55

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28

Pettifer, Anne. "Oral candidiasis and HIV infection." Nursing Standard 6, no. 42 (July 8, 1992): 34–35. http://dx.doi.org/10.7748/ns.6.42.34.s44.

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29

Evans, J., D. S. Orme, M. L. Sedgwick, and G. R. Youngs. "Treating oral candidiasis: potentially fatal." British Dental Journal 182, no. 12 (June 1997): 452. http://dx.doi.org/10.1038/sj.bdj.4809409.

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30

Pemberton, M., P. Sloan, S. Ariyaratnam, N. S. Thakker, and M. H. Thornhill. "Treating oral candidiasis: potentially fatal." British Dental Journal 183, no. 3 (August 1997): 87. http://dx.doi.org/10.1038/sj.bdj.4809429.

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31

Allen, Carl M. "Diagnosing and Managing Oral Candidiasis." Journal of the American Dental Association 123, no. 1 (January 1992): 77–82. http://dx.doi.org/10.14219/jada.archive.1992.0010.

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32

Sharon, Victoria, and Nasim Fazel. "Oral candidiasis and angular cheilitis." Dermatologic Therapy 23, no. 3 (May 2010): 230–42. http://dx.doi.org/10.1111/j.1529-8019.2010.01320.x.

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33

Shaw, N. J., and A. T. Edmunds. "Inhaled beclomethasone and oral candidiasis." Archives of Disease in Childhood 61, no. 8 (August 1, 1986): 788–90. http://dx.doi.org/10.1136/adc.61.8.788.

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34

Barnes, S. E. "Inhaled beclomethasone and oral candidiasis." Archives of Disease in Childhood 62, no. 2 (February 1, 1987): 213. http://dx.doi.org/10.1136/adc.62.2.213-b.

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35

THOMAS, JOHN E., and PATRICK M. LLOYD. "Oral candidiasis in the elderly." Special Care in Dentistry 5, no. 5 (September 1985): 222–25. http://dx.doi.org/10.1111/j.1754-4505.1985.tb00577.x.

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36

Shetty, Kishore. "Fluconazole-Resistant Pseudomembranous Oral Candidiasis." Annals of Pharmacotherapy 40, no. 5 (May 2006): 993. http://dx.doi.org/10.1345/aph.1g629.

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37

SHUSTER, JOEL. "Inhaled steroids and oral candidiasis." Nursing 28, no. 5 (May 1998): 25. http://dx.doi.org/10.1097/00152193-199805000-00012.

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38

Obradović, Radmila R., Ljiljana G. Kesić, Ana N. Pejčić, Milica S. Petrović, Nikola D. Živković, and Dušan M. Živković. "Diabetes mellitus and oral candidiasis." Acta stomatologica Naissi 27, no. 63 (2011): 1025–34. http://dx.doi.org/10.5937/asn1163025o.

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39

van Wyk, C., and V. Steenkamp. "Host factors affecting oral candidiasis." Southern African Journal of Epidemiology and Infection 26, no. 1 (January 2011): 18–21. http://dx.doi.org/10.1080/10158782.2011.11441414.

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40

Dodd, Caroline L., Deborah Greenspan, Mitchell H. Katz, Janice L. Westenhouse, David W. Feigal, and John S. Greenspan. "Oral candidiasis in HIV infection." AIDS 5, no. 11 (November 1991): 1339–44. http://dx.doi.org/10.1097/00002030-199111000-00009.

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41

Challacombe, Stephen J. "Immunologic aspects of oral candidiasis." Oral Surgery, Oral Medicine, Oral Pathology 78, no. 2 (August 1994): 202–10. http://dx.doi.org/10.1016/0030-4220(94)90148-1.

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42

Allen, Carl M. "Animal models of oral candidiasis." Oral Surgery, Oral Medicine, Oral Pathology 78, no. 2 (August 1994): 216–21. http://dx.doi.org/10.1016/0030-4220(94)90150-3.

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43

Pérusse, Rénald. "Oral candidiasis and multiple myeloma." Oral Surgery, Oral Medicine, Oral Pathology 78, no. 2 (August 1994): 264–66. http://dx.doi.org/10.1016/0030-4220(94)90157-0.

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44

Shibata, Tomohisa, Daisuke Yamashita, Shingo Hasegawa, Miki Saito, Naoki Otsuki, Kazunobu Hashikawa, Shinya Tahara, and Ken-ichi Nibu. "Oral candidiasis mimicking tongue cancer." Auris Nasus Larynx 38, no. 3 (June 2011): 418–20. http://dx.doi.org/10.1016/j.anl.2010.11.007.

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45

Nur'aeny, Nanan, Wahyu Hidayat, Tenny Setiana Dewi, Erna Herawati, and Indah Suasani Wahyuni. "Profil oral candidiasis di bagian ilmu penyakit mulut RSHS Bandung periode 2010-2014." Majalah Kedokteran Gigi Indonesia 3, no. 1 (October 31, 2017): 23. http://dx.doi.org/10.22146/majkedgiind.11320.

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Oral candidiasis prole in oral medicine department of RSHS Bandung in the period of 2010 – 2014 C. albicans is the primary causative agent in oral candidiasis. Candida species are commensal microorganisms as normal ora in the mouth, without causing any symptoms. Oral candidiasis may be caused by systemic condition, autoimmune disease and poor oral hygiene.Candida spp can become pathogenic in the decline of the condition of the immune system, especially in autoimmune disease conditions given with steroids drug as the steroids in nature could deteriorate the immune systems or long term of systemic drugs therapy. Study related to oral candidiasis in Indonesia is still lacking. The aim of the study is to know the description of oral candidiasis of RSHS Bandung, Indonesia at 2010 – 2014, descriptively in the oral medicine clinic. The results showed during the period of 2010 to 2014, 49 patients oral candidiasis were found. The most prevalent was 34 males (69.3%) and 15 women (30.7%) in which the most predisposing factor is systemic factor about 40.2%. The whitish pseudomembran plaque is commonly found in the dorsal area of the tongue. The prole of oral candidiasis in patients visiting the oral medicine clinic at RSHS generally is caused by systemic conditions, autoimmune diseases and poor oral hygiene, the use of nystatin is still effective to be used to treat candidiasis.ABSTRAKCandida. albicans (C.albicans) merupakan agen penyebab primer pada oral candidiasis. Candida spp merupakan mikroorganisme komensal atau ora normal dalam mulut dengan tanpa menimbulkan gejala. Candida spp dapat menjadi patogen saat kondisi daya tahan tubuh menurun terutama dalam kondisi penyakit autoimun yang diberikan terapi steroid karena steroid bersifat menurunkan sistem imun atau terapi obat-obatan secara sistemik dalam jangka waktu lama. Penelitian oral candidiasis di Indonesia masih belum banyak dilakukan. Penelitian ini bertujuan untuk mengetahui prol oral candidiasis pada pasien-pasien yang ditangani di Bagian Penyakit Mulut di Rumah Sakit dr. Hasan Sadikin (RSHS), Bandung, Indonesia periode tahun 2010 – 2014. Hasil penelitian menunjukkan selama periode 2010 hingga 2014 sebanyak 49 orang pasien yang datang ke klinik ilmu penyakit mulut ditemukan oral candidiasis. Prevalensi terbanyak adalah pria sebesar 34 orang (69,3%) dan wanita 15 orang (30,7%), dengan faktor predisposisi terbanyak adalah keterlibatan penyakit sistemik sebesar 40,2%. Lokasi paling sering ditemukan lesi plak pseudomembran putih dan terdapat di daerah dorsal lidah. Prol kandidiasis pada pasien yang berkunjung ke klinik ilmu penyakit mulut RSHS secara garis besar umumnya disebabkan oleh kondisi sistemik, penyakit autoimun dan kebersihan rongga mulut yang buruk sedangkan untuk terapi kandidiasis, penggunaan nystatin masih efektif untuk digunakan mengobati kandidiasis.

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Hernawati, Sri. "Relationship between Nutrition Deficiency, Oral Cavity Hygiene, and Oral Candidiasis in a 10-Years-Old Child." Health Notions 3, no. 10 (October 28, 2019): 469. http://dx.doi.org/10.33846/hn31003.

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Candida albicans (C.albicans) is the main causative agent in oral candidiasis. Candida spp is a commensal microorganism or normal flora in the mouth without causing symptoms. Candida spp can be a pathogen when the body's condition decreases, systemic medical therapy for a long time, nutritional deficiencies and poor oral hygiene. This study aimed to determine the predisposing factors for the causes of oral candidiasis in 10-year-old pediatric patients who came to the Department of Oral Medicine, Dental Hospital of Dentistry Faculty of Jember University. The results of this study indicate a relationship between nutritional deficiencies and poor oral hygiene with oral candidiasis in children. White pseudomembranous plaque lesions are mostly found in the dorsal area of the tongue. Therapy for the patients is by applying nystatin anti-fungal, multivitamins, and education to improve nutrition and oral hygiene. Keywords: nutritional deficiency; the oral cavity hygiene; oral candidiasis

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Ito, Rei, Yuichi Mine, Yoshie Yumisashi, Reina Yoshioka, Misa Hamaoka, Tsuyoshi Taji, Takeshi Murayama, and Hiroki Nikawa. "In Vivo Efficacy of Lacticaseibacillus rhamnosus L8020 in a Mouse Model of Oral Candidiasis." Journal of Fungi 7, no. 5 (April 21, 2021): 322. http://dx.doi.org/10.3390/jof7050322.

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Oral candidiasis presents with multiple clinical manifestations. Among known pathogenic Candida species, Candida albicans is the most virulent and acts as the main causative fungus of oral candidiasis. Novel treatment modalities are needed because of emergent drug resistance and frequent candidiasis recurrence. Here, we evaluated the ability of Lacticaseibacillus rhamnosus L8020, isolated from healthy and caries-free volunteers, to prevent against the onset of oral candidiasis in a mouse model. Mice were infected with C. albicans, in the presence or absence of L. rhamnosus L8020. The mice were treated with antibiotics and corticosteroid to disrupt the oral microbiota and induce immunosuppression. We demonstrated that oral consumption of L. rhamnosus L8020 by C. albicans-infected mice abolished the pseudomembranous region of the mouse tongue; it also suppressed changes in the expression levels of pattern recognition receptor and chemokine genes. Our results suggest that L. rhamnosus L8020 has protective or therapeutic potential against oral candidiasis, which supports the potential use of this probiotic strain for oral health management.

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Nakajima, Masato, Yojiro Umezaki, Masahiro Yamaguchi, Michiko Makino, Nao suzuki, Masahiro Yoneda, Takao Hirofuji, and Hiromitsu Morita. "BACTERIAL PNEUMONIA IS A POSSIBLE RISK FACTOR FOR ORAL CANDIDIASIS IN OLDER ADULTS: A RETROSPECTIVE COHORT STUDY." Innovation in Aging 3, Supplement_1 (November 2019): S869. http://dx.doi.org/10.1093/geroni/igz038.3189.

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Abstract Both aspiration pneumonia and oral candidiasis are caused by opportunistic infection of intraoral commensals and have many similar risk factors linked to oral health in older adults. Candida albicans forms biofilms with respiratory bacteria such as Klebsiella pneumoniae and Pseudomonas aeruginosa. The aim of our study was to determine the relationship between bacterial pneumonia, including aspiration pneumonia, and oral candidiasis in older patients who were hospitalized with several systemic diseases in a community-based acute care hospital without a dental unit. We retrospectively analyzed 228 older patients (male: 105, female: 123) using multiple logistic regression. The mean age of the patients was 81.3 (SD: 11.1) years. Forty-four patients were oral candidiasis positive, and 78 patients suffered from bacterial pneumonia, including aspiration pneumonia. Results showed that bacterial pneumonia had the strongest statistical relationship with oral candidiasis (p=0.000, OR: 5.173, 95 % CI: 2.368–11.298). This was followed by poor oral hygiene (p=0.001, OR: 6.095, 95 % CI: 2.003–18.545) and severe dry mouth (p=0.043, OR: 2.507, 95 % CI: 1.031–6.098). Other conventional risk factors for oral candidiasis, such as diabetes mellitus, denture wearer, dysphagia, malnutrition, requiring care, use of inhalation steroids, were not statistically significant in this study. Fifteen species of bacteria, including Klebsiella pneumoniae and Pseudomonas aeruginosa, were detected by pharyngeal sputum culture in 24 of 31 patients who were diagnosed with both oral candidiasis and bacterial pneumonia. In conclusion, bacterial pneumonia is a possible new risk factor for oral candidiasis in older adults.

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Ishijima, Sanae A., Kazumi Hayama, Jeremy P. Burton, Gregor Reid, Masashi Okada, Yuji Matsushita, and Shigeru Abe. "Effect of Streptococcus salivarius K12 on the In Vitro Growth of Candida albicans and Its Protective Effect in an Oral Candidiasis Model." Applied and Environmental Microbiology 78, no. 7 (January 20, 2012): 2190–99. http://dx.doi.org/10.1128/aem.07055-11.

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ABSTRACTOral candidiasis is often accompanied by severe inflammation, resulting in a decline in the quality of life of immunosuppressed individuals and elderly people. To develop a new oral therapeutic option for candidiasis, a nonpathogenic commensal oral probiotic microorganism,Streptococcus salivariusK12, was evaluated for its ability to modulateCandida albicansgrowthin vitro, and its therapeutic activity in an experimental oral candidiasis model was tested.In vitroinhibition of mycelial growth ofC. albicanswas determined by plate assay and fluorescence microscopy. Addition ofS. salivariusK12 to modified RPMI 1640 culture medium inhibited the adherence ofC. albicansto the plastic petri dish in a dose-dependent manner. Preculture ofS. salivariusK12 potentiated its inhibitory activity for adherence ofC. albicans. Interestingly,S. salivariusK12 was not directly fungicidal but appeared to inhibitCandidaadhesion to the substratum by preferentially binding to hyphae rather than yeast. To determine the potentially anti-infective attributes ofS. salivariusK12 in oral candidiasis, the probiotic was administered to mice with orally induced candidiasis. Oral treatment withS. salivariusK12 significantly protected the mice from severe candidiasis. These findings suggest thatS. salivariusK12 may inhibit the process of invasion ofC. albicansinto mucous surfaces or its adhesion to denture acrylic resins by mechanisms not associated with the antimicrobial activity of the bacteriocin.S. salivariusK12 may be useful as a probiotic as a protective tool for oral care, especially with regard to candidiasis.

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Lira, Ana de Lourdes Sá de, and Aline Cardoso Torres. "Relationship between oral candidiasis and users of dental prostheses." Brazilian Journal of Oral Sciences 17 (July 10, 2018): 1–11. http://dx.doi.org/10.20396/bjos.v17i0.8652906.

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Aim: To investigate the relationship between oral candidiasis and users of dental prostheses. Methods: A cross-sectional study was carried out which the inclusion of adults and elderly people of both genders using dental prostheses. Lectures were given with guidelines on oral hygiene techniques and dental prostheses, preventive measures of candidiasis, highlighting their influence on the oral and general health of the individual for the 240 users of dental prostheses. Of this number, 153 did not want to participate in the clinical examination. Signals and symptoms were analyzed in 87 patients, and lesions were present in only 21, and a cytological complement of the lesions was performed. Data were analyzed using SPSS version 15.0 with Chi-square (χ2 ) test at p < 0.05. Results: The 21 patients presented oral candidiasis, with erythematous (prosthetic) stomatitis being the most prevalent. There was a correlation between the presence of Candida and the use of prostheses (p- value 0.00*). Candidiasis was associated with poorly adapted prostheses, poor oral hygiene, inadequate prostheses and prolonged use of them. Conclusion: There was a correlation between oral candidiasis and users of dental prostheses. The most prevalent type of candidiasis was erythematous stomatitis (prosthetic), and nystatin was used to treat all cases. The preventive activities carried out were extremely important, since patients were not aware of oral candidiasis and the factors that trigger it, such as poor oral hygiene and dental prostheses.

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