Log in

Relevant bibliographies by topics / Oral Disintegrating Tablets / Journal articles

To see the other types of publications on this topic, follow the link: Oral Disintegrating Tablets.

Journal articles on the topic 'Oral Disintegrating Tablets'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Oral Disintegrating Tablets.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Sneha, Ms Shinde. "Review Article A Detailed Study on Disintegrating Agents and an Overview on Oral Disintegration Tablet." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 04 (2024): 1–5. http://dx.doi.org/10.55041/ijsrem30535.

Full text

Abstract:

Nowadays, the administration of drugs through the oral route is becoming less common, accounting for only about 75% of all drug administrations compared to other routes. A new type of dosage form called oral disintegrating tablets has gained popularity in recent decades due to their rapid disintegration and dissolution. These tablets disintegrate in the mouth within seconds (25-40 seconds) without the need for water, as the oral mucosa alone is sufficient for the tablet to dissolve. The selection of a suitable disintegrating agent is crucial to achieve optimal bioavailability. A preparation ma

APA, Harvard, Vancouver, ISO, and other styles

2

M T, Ranjitha, and C. N. Somashekhar. "PREPARATION AND EVALUATION OF MEFENAMIC ACID AND DICYCLOMINE HYDROCHLORIDE AS ORAL DISINTEGRATING TABLET BY DIRECT COMPRESSION METHOD." Journal of Pharmaceutical and Scientific Innovation 10, no. 4 (2021): 94–101. http://dx.doi.org/10.7897/2277-4572.104211.

Full text

Abstract:

A new dosage form, Oral disintegrating tablets (ODT’s) as a replacement to conventional oral dosage forms. ODT’s are dosage forms they disintegrate in mouth offering various advantages such as better mouth feel, dose accuracy, improved stability and convenient dosing as compared to oral liquids. So, there is need to designed oral disintegrating tablet to release the medicaments with an enhanced rate. Mefenamic acid is an anti- inflammatory drug while Dicyclomine HCl is anti-cholinergic drug. The combination of Mefenamic acid & Dicyclomine HCl controls pain very effectively, also relaxes bo

APA, Harvard, Vancouver, ISO, and other styles

3

Eremin, V. A., E. V. Blynskaya, and V. V. Bueva. "Orally disintegrating tablets: mechanisms, preparation methods, problems and achievements." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 6 (December 19, 2023): 25–32. http://dx.doi.org/10.33920/med-13-2306-03.

Full text

Abstract:

The oral route of drug administration is considered one of the preferred delivery methods. In recent years, orally disintegrating tablets (ODTs) have become convenient pharmaceutical dosage forms, especially for specific patient populations such as pediatric, geriatric, and psychiatric patients with dysphagia. Rapid disintegration and increased bioavailability are some of the essential characteristics of ODTs that make them superior to other traditional pharmaceutical dosage forms. Orally disintegrating tablets are pills that disintegrate within a few seconds after being placed in the oral cav

APA, Harvard, Vancouver, ISO, and other styles

4

Joshi, Apeksha, Narendra Gahelot, Vikas Jain, and SC Mahajan. "Rapid disintegrating tablets: an effective method for accelerating the therapeutic action of poorly soluble Drugs." Journal of Drug Delivery and Therapeutics 12, no. 1 (2022): 208–13. http://dx.doi.org/10.22270/jddt.v12i1.5174.

Full text

Abstract:

The ease of administration and increased patient compliance are critical factors in the design of oral drug delivery systems, which continue to be the dominant method of drug delivery despite numerous shortcomings. The rapid disintegrating tablet (RDT) could be a great alternative to traditional tablets because it dissolves quickly when it comes into contact with saliva. Rapid disintegrating tablets (RDTs) are currently more widely available than other tablets to treat various disorders. Due to its ease of manufacture and administration, oral administration is being investigated as the most fr

APA, Harvard, Vancouver, ISO, and other styles

5

Patel, Afroza Akbar, Siraj N. Shaikh, Huzaifa Patel, Afzal Band, and Ahmed Shaoor. "Designing fabrication and evaluation of Oral fast Disintegrating tablet of Ranitidine HCL." Journal of Drug Delivery and Therapeutics 9, no. 1 (2019): 95–102. http://dx.doi.org/10.22270/jddt.v9i1.2176.

Full text

Abstract:

The aim of this research work was to design develop & evaluate oral fast disintegrating tablets of Ranitidine HCL. The Orodispersible tablets of Ranitidine HCl were prepared by using direct Compression technique with a Synthetic Superdisintegrant such as Crosspovidone and a natural Superdisintegrant Fenugreek gum in different concentration. 32 factorial designs was applied to study the effect of independent variables, concentration of Crosspovidone & Fenugreek gum on dependent variables like Cumulative % Drug release and Disintegration time by using design expert software. Prepared ora

APA, Harvard, Vancouver, ISO, and other styles

6

Swarupa, Arvapalli* D. Swamy Shyamala. "ORAL DISINTEGRATION TABLETS – AN UPDATED REVIEW." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6926–34. https://doi.org/10.5281/zenodo.2617331.

Full text

Abstract:

<em>The purpose of writing this review is Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. It is leads to development of orally disintegrating tablets. This disintegrates in the mouth in seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. The prepared tablets were evaluated for hardness, friability, disintegration time

APA, Harvard, Vancouver, ISO, and other styles

7

Kumar, Y. Shravan, Karnakar M, Harika S, and Mounika M. "Formulation and Evaluation of Salbutamol Sulphate Taste Masked Oral Disintegrating Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 4 (2021): 5571–76. http://dx.doi.org/10.37285/ijpsn.2021.14.4.7.

Full text

Abstract:

Salbutamol is a short acting, selective beta2-adrenergic receptor agonist used in the treatment of astama and COPD. The aim of this study is to formulate oral disintegrating tablets of salbutamol sulphate to achieve rapid dissolution, absorption and further improving the bioavailability of the drug. Oral disintegrating tablets of salbutamol sulphate were designed with a view to enhance the patient compliance and provide a quick onset of action. The oral disintegrating tablets were prepared by using different synthetic polymers by direct compression method. Development of the formulation in the

APA, Harvard, Vancouver, ISO, and other styles

8

Rakesh, Pahwa* Shwetakshi Sharma Abhinav Singh Rana Anshul Garg and Inderbir Singh. "EMERGENCE OF NATURAL SUPERDISINTEGRANTS IN THE DEVELOPMENT OF ORALLY DISINTEGRATING TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 03, no. 08 (2016): 777–87. https://doi.org/10.5281/zenodo.153851.

Full text

Abstract:

Orally disintegrating tablets have carved a significant role amongst the oral drug delivery systems owing to their enhanced patient compliance especially in the geriatrics and pediatrics. These tablets offer numerous substantial advantages over conventional dosage forms because of improved efficacy, bioavailability and rapid onset of action. Use of natural superdisintegrants in the development of orally disintegrating tablets has numerous benefits such as chemically inert, non-toxic, less expensive, biodegradable and widely available. The present manuscript is an earnest attempt to illustrate

APA, Harvard, Vancouver, ISO, and other styles

9

&NA;. "Ondansetron Oral Disintegrating Tablets." Survey of Anesthesiology 50, no. 3 (2006): 143–44. http://dx.doi.org/10.1097/01.sa.0000220745.07169.7f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Chue, Pierre, Barry Jones, Cindy C. Taylor, and Ruth Dickson. "Dissolution Profile, Tolerability, and Acceptability of the Orally Disintegrating Olanzapine Tablet in Patients with Schizophrenia." Canadian Journal of Psychiatry 47, no. 8 (2002): 771–74. http://dx.doi.org/10.1177/070674370204700809.

Full text

Abstract:

Objectives: This pilot study investigates the dissolution profile, tolerability, and acceptability of an orally disintegrating olanzapine tablet in patients with schizophrenia. Method: Eleven patients with schizophrenia stabilized on oral olanzapine (mean dosage 12.7 mg daily [SD5.2]) were given an orally disintegrating olanzapine tablet, rather than their usual tablet, daily for 7 days. At each visit, visual assessments were made for elapsed time to initial disintegration (every 15 seconds) and complete disintegration (every 1 minute). At the end of the study, patients completed a drug-accept

APA, Harvard, Vancouver, ISO, and other styles

11

Singhal, Peeush. "OPTIMIZED FAST DISINTEGRATING TABLETS, BOOSTED OSELTAMIVIR PHOSPHATE ORALLY FAST DISINTEGRATING TABLETS." Journal of Medical pharmaceutical and allied sciences 10, no. 6 (2021): 3781–88. http://dx.doi.org/10.22270/jmpas.v10i6.1479.

Full text

Abstract:

Background Around 33% of the populace (fundamentally pediatric and geriatric) has gulping hardships, bringing about helpless consistence with oral tablet drug treatment which prompts decreased in general treatment viability. For this explanation, tablets that can quickly break down or deteriorate in the oral cavity have drawn in a lot of consideration. Objective research was designed to develop and evaluate boosted orally fast disintegrating tablets (OFDT) for oro-buccal drug delivery of oseltamivir phosphate. Methods In the present study six formulations of mouth dissolving tablet of oseltami

APA, Harvard, Vancouver, ISO, and other styles

12

Kumar Bhasin, Rakesh, Nirika Bhasin, and Pradip Kumar Ghosh. "Advances in Formulation of Orally Disintegrating Dosage Forms: A Review Article." Indo Global Journal of Pharmaceutical Sciences 01, no. 04 (2011): 328–53. http://dx.doi.org/10.35652/igjps.2011.33.

Full text

Abstract:

Oral disintegrating tablets are solid dosage form containing medicinal substances which disintegrates rapidly, usually within a matter of seconds, when placed upon the tongue The products are designed to disintegrate or dissolve rapidly on contact with saliva, thus eliminating the need for chewing the tablet, swallowing an intact tablet, or taking the tablet with water. ODT is general form of nomenclature for tablets that disintegrate rapidly or instantly in the oral cavity. Other alias are Quick Dissolve, Rapid Dissolve, Rapid Disintegrating, Fast Disintegrating, Fast Melt, Flash Melt and Mou

APA, Harvard, Vancouver, ISO, and other styles

13

Alami-Milani, Mitra, Sara Salatin, Elaheh Nasiri, and Mitra Jelvehgari. "Preparation and optimization of fast disintegrating tablets of isosorbide dinitrate using lyophilization method for oral drug delivery." Therapeutic Delivery 12, no. 7 (2021): 523–38. http://dx.doi.org/10.4155/tde-2020-0127.

Full text

Abstract:

Background: Orally disintegrating tablets rapidly disintegrate in saliva and then swallowed without the need for water. Materials & methods: The orally disintegrating tablets were prepared by freeze-drying of an aqueous dispersion of isosorbide dinitrate containing a matrix former (gelatin), a cryoprotectant (mannitol), a plasticizer (glycerin) and a dissolution enhancer (Tween/polyethylene glycol). Results: Results demonstrated that the selected formulation, Ft9, disintegrated within 1 min and showed faster dissolution rate compared with the commercial tablet. Conclusion: Having a fast di

APA, Harvard, Vancouver, ISO, and other styles

14

El-Say, Khalid M., Tarek A. Ahmed, Maged F. Abdelbary, Bahaa E. Ali, Bader M. Aljaeid, and Ahmed S. Zidan. "Risperidone oral disintegrating mini-tablets: A robust-product for pediatrics." Acta Pharmaceutica 65, no. 4 (2015): 365–82. http://dx.doi.org/10.1515/acph-2015-0038.

Full text

Abstract:

Abstract This study was aimed at developing risperidone oral disintegrating mini-tablets (OD-mini-tablets) as age-appropriate formulations and to assess their suitability for infants and pediatric use. An experimental Box-Behnken design was applied to assure high quality of the OD-mini-tablets and reduce product variability. The design was employed to understand the influence of the critical excipient combinations on the production of OD-mini-tablets and thus guarantee the feasibility of obtaining products with dosage form uniformity. The variables selected were mannitol percent in Avicel (X1)

APA, Harvard, Vancouver, ISO, and other styles

15

K., Ramanji Reddy* Dr. S. Jaya R.Srikanth Dr. Chandaka Madhu. "FORMULATION AND EVALUATION OF LAMOTRIZINE ORODISPENSIBLE TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 769–78. https://doi.org/10.5281/zenodo.1174207.

Full text

Abstract:

The aim of the present study was to develop and optimize oral disintegrating tablets of model drug (Lamotrizine) to give quick onset of action by rapidly disintegrating in a few seconds without the need of water with better patient compliance. In such cases, bioavailability of drug is significantly greater and adverse event is reduced than those observed from conventional tablet dosage form. By performing compatibility studies by IR spectrophotometry, no interaction was confirmed. Oral disintegrating tablets were formulated by direct compression method and evaluated by UV-Visibile spectrophoto

APA, Harvard, Vancouver, ISO, and other styles

16

Rahane, RD, and Punit R. Rachh. "A REVIEW ON FAST DISSOLVING TABLET." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 50–55. http://dx.doi.org/10.22270/jddt.v8i5.1888.

Full text

Abstract:

The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. The popularity and usefulness of the formulation resulted in development of several FDT technologies. These techniques render the disintegration of tablet rapidly and dissolve in mouth in five seconds without chewing

APA, Harvard, Vancouver, ISO, and other styles

17

Wu, Tong, Guanhua Wang, Caihong Shi, et al. "Development and evaluation of orally disintegrating tablets containing the mosapride resin complex." Acta Pharmaceutica 68, no. 2 (2018): 159–70. http://dx.doi.org/10.2478/acph-2018-0017.

Full text

Abstract:

Abstract The purpose of this study was to prepare a mosapride citrate-resin (Amberlite® IRP 88) complex and orally fast-disintegrating tablets of the resin complex. The resinate complex of mosapride-Amberlite® IRP 88, mass ratio 2:1, was prepared in an ethanol-water solution. The effects of alcohol concentration, temperature, and pH of the solution on complex formation were evaluated. The complex physicochemical properties were characterized by differential scanning calorimetry, X-ray diffraction and scanning electron microscopy. Orally disintegrating tablets were prepared by direct compressio

APA, Harvard, Vancouver, ISO, and other styles

18

Aly, Adel M., and A. A. Mohammed. "Preparation and Evaluation of Sildenafil Rapidly Disintegrating Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 5, no. 1 (2012): 1617–20. http://dx.doi.org/10.37285/ijpsn.2012.5.1.4.

Full text

Abstract:

Sildenafil citrate is an oral therapy for erectile dysfunction (ED). Sildenafil, a selective inhibitor of cyclic guanosine monophosphate-specific phosphodiesterase type 5 (PDE5), has been reported to be effective in men with ED associated with diabetes and prostate cancer, and in psychogenic ED. The main objective of this study is to prepare more effective, rapidly disintegrating and rapid onset of action sildenafil oral tablets. Sildenafil tablets were prepared using the newly introduced Pharmaburst® as a direct compression vehicle in comparison with the well-known excipients, namely mannitol

APA, Harvard, Vancouver, ISO, and other styles

19

Mane, Swapna, Ritesh Bathe, and Sandhyarani Awatade. "Formulation and Evaluation of Fast Disintegrating Tablets of Atenolol Using Natural and Synthetic Superdisintegrants." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 150–58. http://dx.doi.org/10.22270/jddt.v9i2-s.2476.

Full text

Abstract:

Oral disintegrating tablet (ODT) is defined as “A solid dosage form containing medical substances or active ingredient which disintegrates rapidly usually within a matter of seconds when placed upon the tongue”. The aim of the present research is to formulate Atenolol fast disintegrating tablets. Atenolol is β1- cardio selective adrenergic receptor blocker, widely used in the treatment of hypertension, angina pectoris, arrhythmias and myocardial infarction. It works by slowing down the heart and reducing the work load of the heart. The conventional tablets of atenolol are reported to exhibit f

APA, Harvard, Vancouver, ISO, and other styles

20

Rama Rao, T., and S. Anila. "ORAL DISINTEGRANTING TABLETS: AN OVERVIEW." International Journal of Advanced Research 12, no. 07 (2024): 240–52. http://dx.doi.org/10.21474/ijar01/19049.

Full text

Abstract:

Especially for patients who have dysphagia or difficulty swallowing, oral disintegrating tablets (ODTs) have developed as a novel dosage form to address a number of issues related to traditional solid dosage forms. An overview of the formulation techniques, assessment criteria, and uses of ODTs in pharmaceutical research are given in this study. In order to accomplish quick disintegration and dissolution of the tablet matrix upon contact with saliva, formulation processes such as sublimation, lyophilization, and direct compression have been thoroughly investigated. When evaluating the quality

APA, Harvard, Vancouver, ISO, and other styles

21

Eremin, V. A., and E. V. Blynskaya. "Modern approaches to assessing the quality of orally disintegrating tablets." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 6 (December 19, 2023): 8–17. http://dx.doi.org/10.33920/med-13-2306-01.

Full text

Abstract:

Orally disintegrating tablets (ODTs) are the preferred and accepted solid dosage forms by patients. These tablets disintegrate in the oral cavity within a short period, providing an advantage for individuals who have difficulty swallowing. Quality control of ODTs can be achieved through measures such as friability, porosity, hardness, wetting time, water absorption capacity, in vitro disintegration test, and dissolution test. This article summarizes the advantages and in vitro quality control tests of orally disintegrating tablets.

APA, Harvard, Vancouver, ISO, and other styles

22

Shah, Ria, Disha Patel, Dhruvanshi Kothari, et al. "Formulation and Evaluation of Oral dispersible Tablet of Paroxetine Hydrochloride." Journal of Drug Delivery and Therapeutics 11, no. 4 (2021): 41–47. http://dx.doi.org/10.22270/jddt.v11i4.4921.

Full text

Abstract:

Orodispersible tablets (ODTs) is one such novel approach which helps to increase user acceptance by virtue of rapid disintegration, self-administration without water or chewing. ODTs are solid unit dosage forms like the conventional tablets containing super disintegrants, which help them to disintegrate and/or disperse rapidly in the mouth within few seconds. The orodispersible tablet of Paroxetine hydrochloride was prepared by using direct compression method and the tablet were formulated using various concentration of Kyron T-314 as disintegrating agent, PVP K-30 as binder, F melt Type C as

APA, Harvard, Vancouver, ISO, and other styles

23

Raihan, Roshaan, Azimullah Wafa, Aqa Mohammad Zhakfar, and Sudhakar CK. "Oral Disintegrating Films: A Review." Journal of Natural Science Review 2, no. 2 (2024): 60–74. http://dx.doi.org/10.62810/jnsr.v2i2.42.

Full text

Abstract:

The oral route stands out as a preferred method for drug administration due to its cost-effectiveness and ease, contributing to enhanced patient compliance. Some individuals, particularly the geriatric and pediatric populations, encounter difficulties swallowing conventional tablets and hard gelatin capsules. To address this, oral disintegrating drug delivery systems are established as substitutes for tablets, capsules, and syrups. Notably, fast-dissolving oral thin films offer a practical solution for patients such as those in pediatric, bedridden, or developmentally disabled categories, as w

APA, Harvard, Vancouver, ISO, and other styles

24

J.Nasser, Saddam, Laith H. Sameen, and Mowafaq M.Ghareeb. "Preparation and Evaluation of Oral Disintegrating Tablets of Ketoprofen by Dirct Compression." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 21, no. 2 (2017): 63–68. http://dx.doi.org/10.31351/vol21iss2pp63-68.

Full text

Abstract:

Ketoprofen is a non-steroidal anti-inflammatory (NSAID) drug with analgesic, anti-inflammatory, and antipyretic effects. It is widely used in the treatment of inflammation and pain associated with rheumatic disorders such as rheumatoid arthritis, osteoarthritis, and in soft tissue injury. The purpose of this study was to prepare an oral disintegrating tablets of ketoprofen by simple method. The tablets were prepared by direct compression method and different ratios of various subliming agents or superdisintegrants were incorporated. Then these tablets were evaluated for hardness, friability, w

APA, Harvard, Vancouver, ISO, and other styles

25

A., Deevan Paul* P. Nagaraj E. Reshma T. Mahesh Y. Divyasree. "CHALLENGES IN NANOTECHNOLOGY DRUG DELIVERY SYSTEMS - STATE OF ART TECHNOLOGIES." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1550–58. https://doi.org/10.5281/zenodo.816203.

Full text

Abstract:

The potential challenges to solve the poor solubility, limited chemical stability in vitro and in vivo after administration (i.e. short half-life), poor bioavailability and potentially strong side effects requiring drug enrichment at the site of action (targeting). This review describes the use of nanoparticulate carriers, developed in our research group, as one solution to overcome the dosage forms. The performance of ODTs depends on the technology used in their manufacture. The orally disintegrating property of these tablets is attributable to the quick ingress of water into the tablet matri

APA, Harvard, Vancouver, ISO, and other styles

26

C., Haranath* T. Srikanth M. Suresh Krishna G. Chaithanya Barghav C. Mahesh Reddy. "FORMULATION AND INVITRO EVALUATION OF FAST DISINTEGRATING TABLETS OF AN ANTI-INFLAMMATORY DRUG." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 10790–99. https://doi.org/10.5281/zenodo.3229226.

Full text

Abstract:

<em>Oral disintegrating tablets are defined as the tablets that disperse or disintegrates in less than one minute in the mouth prior to being swallowed, which results in the rapid dissolution and absorption of the active pharmaceutical ingredient contained in the tablet, providing rapid onset of action. Aceclofenac is a poorly water-soluble drug. The solubility of the drug was enhanced by solid dispersion technique using mannitol as the carrier. In the present study, 9 formulations were developed by using different super disintegrants like cross povidone, sodium starchglycolate and cross carme

APA, Harvard, Vancouver, ISO, and other styles

27

Kumar, Y. Shravan, Prashanthi Patel, Sravanthi Ch, and Rashmi B. "Formulation and Evaluation of Taste Masked Oral Disintegrating Tablets of Aripiprazole." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 1 (2015): 2723–34. http://dx.doi.org/10.37285/ijpsn.2015.8.1.4.

Full text

Abstract:

 Aripiprazole is an atypical antipsychotic agent used for treatment of schizophrenia, bipolar disorder and major depressive disorders. In the present work, oral disintegrating tablets of aripiprazole were developed to enhance the patient compliance and provide rapid onset of action. The efficacy of aripiprazole is mediated through a combination of partial agonist activity at dopamine D2 and serotonin 5HT-1A receptors and antagonist activity at 5HT-2A receptors. It has a bitter taste and poor-solubility in water. Thus, the main objective of the study is to formulate taste masked oral disi

APA, Harvard, Vancouver, ISO, and other styles

28

Rohit, Khandare* Sarika Nikam. "Formulation and Evaluation of Oral Disintegrating Tablets Containing Clove Powder as an Analgesic for Toothache." International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 1349–56. https://doi.org/10.5281/zenodo.14880896.

Full text

Abstract:

Objective: This study aims to formulate and evaluate oral disintegrating tablets (ODTs) incorporating clove powder as an analgesic for toothache. Clove is rich in eugenol and has shown analgesic activity, antimicrobial, and anti-inflammatory, and has been used as a traditional remedy for tooth pain. This study included Clove powder in ODTs to guarantee quick dissolving and timely toothache treatment for patients. The difficulty, though, is in creating a dose form that is both efficient and patient-friendly. Among the many benefits of oral disintegrating pills are their quick onset of action an

APA, Harvard, Vancouver, ISO, and other styles

29

M, Nandhini, Vijaya Kumar Voleti, Ramesh Yamuna, et al. "Applications of the Natural Polymers for Fast Dissolving Tablets." International Journal of Clinical Pharmacokinetics and Medical Sciences 4, no. 1 (2024): 34–40. http://dx.doi.org/10.26452/ijcpms.v4i1.584.

Full text

Abstract:

Oral route is the safest, most convenient, and economical route for administration of different drugs. Oral disintegrating tablets becoming very popular in the current scenario, as they facilely disintegrated in mouth within fewseconds of the time after its administration withoutthe need of water. Conventional dosage form has a limitations like dysphagia (arduousness in swallowing), in pediatric and geriatric patients, which have been overcome by oral disintegrating tablets. To prepare the same super disintegrating agents plays vital role. Natural Super disintegrants gained an advantage over t

APA, Harvard, Vancouver, ISO, and other styles

30

K., Rekha Rani Y. Navya Reddy R. Mohana Priya G.Anusha and T. Spurthi. "FORMULATION AND EVALUATION OF ORAL DISINTEGRATION TABLETS OF OMEPRAZOLE." indo American Journal of Pharmaceutical Sciences 04, no. 05 (2017): 1391–97. https://doi.org/10.5281/zenodo.804918.

Full text

Abstract:

Omeprazole fast disintegrating tablets were prepared by using different superdisintegrants like crospovidone, croscarmellose sodium and Sodium starch glycolate by direct compression. Precompression parameters were conducted for all formulations blend and were found to be satisfactory. The prepared tablets were evaluated for various parameters like content uniformity, hardness, friability, wetting time, water absorption ratio, disintegration time and In-vitro dissolution. The results indicated that the tablets complied with the official specifications. The disintegration studies shown that the

APA, Harvard, Vancouver, ISO, and other styles

31

Siddheshwar, Suhas Shivaji, Asmita Bhausaheb Ghorpade, Someshwar Dattatraya Mankar, and Santosh Bhausaheb Dighe. "Formulation and Drug Release Study of Rivaroxaban Oral Disintegrating Tablets Using Various Super-Disintegrants." International Journal of Experimental Research and Review 36 (December 30, 2023): 147–55. http://dx.doi.org/10.52756/ijerr.2023.v36.014.

Full text

Abstract:

This study aims to improve Rivaroxaban's solubility, dissolution, and bioavailability. Orally disintegrating tablets (ODTs) made with super-disintegrants like crospovidone, sodium starch glycolate, and cross-carmellose sodium will do this. Tablet preparation used direct compression and formulation optimization with design expert software. After a thorough factorial design and evaluation of pre- and post-compression parameters, the F3 batch, which contained Rivaroxaban (7.97%), Crospovidone (3.59%), Croscarmellose sodium (5.18%), Sodium Starch Glycolate (5.18%), Lactose Anhydrous (31.08%), Mann

APA, Harvard, Vancouver, ISO, and other styles

32

Jaya, S., and V. Amala. "FORMULATION AND IN VITRO EVALUATION OF ORAL DISINTEGRATING TABLETS OF AMLODIPINE BESYLATE." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 49. http://dx.doi.org/10.22159/ijap.2019v11i1.28457.

Full text

Abstract:

Objective: The present investigation was undertaken with an objective of formulating oral disintegrating tablets of amlodipine besylate to enhance convenience and compliance of the elderly and pediatric patients for better therapeutic efficacy.Methods: The tablets were prepared by using direct compression method and evaluated for weight variation, hardness, friability, wetting time, disintegration time and in vitro drug release study. Prepared tablets were evaluated for compatibility by Fourier transform infrared spectroscopy.Results: Fourier transform infrared spectroscopy studies revealed th

APA, Harvard, Vancouver, ISO, and other styles

33

RK, Gunda. "Effect of Crospovidone, Croscaramellose Sodium in Combination on the Drug Release of Anti diabetic Medication in Tablet Form." Pharmaceutical Drug Regulatory Affairs Journal 7, no. 1 (2024): 1–7. http://dx.doi.org/10.23880/pdraj-16000159.

Full text

Abstract:

Objective: The current study’s objective is to check the impact of superdisintegrants on the drug release of Vildagliptin by developing oral disintegrating tablets (ODT). Vildagliptin, new class of oral hypoglycemic agent. It acts by inhibiting dipeptidyl peptidase-4. Conventional Vildagliptin tablets are (due to its first pass effect) unsuitable where quicker onset of action is required Hence, it is necessary to develop oral disintegrating tablet, in order to obtain improved patient compliance. Methods: Using Oral disintegrating tablets of Vildagliptin were prepared using various quantities o

APA, Harvard, Vancouver, ISO, and other styles

34

Iswariya, V. T., Nambaaru Sailaja, CH Vamsi Krishna, and G. S. Annammadevi. "Natural Super-Disintegrant Agents Used in Various Oral Solid Dosage Forms." Journal of Drug Delivery and Therapeutics 11, no. 1 (2021): 110–13. http://dx.doi.org/10.22270/jddt.v11i1.4681.

Full text

Abstract:

Super-disintegrating agents are one of the ingredients used in pharmaceutical solid dosage forms. These substances play a vital role in formulation design. Natural super-disintegrants have gained more popularity due to their oral bioavailability. It disintegrates the tablets into smaller particles to enhance the dissolution rate. Fast dissolving, chewable tablets, and other orally administered dosage forms consist of super-disintegrating agents which shows rapid and quick action. Natural super disintegrating agents in pharmaceutical dosage forms are very effective due to their ecofriendly natu

APA, Harvard, Vancouver, ISO, and other styles

35

Rao.S, Kameswara, Yusuf MD., Saraswathi P., Ch R. Raghavendra Rao, Murali P., and Vijayakumar V. "Formulation and evaluation of orodispersible Enalapril maleate tablets: a comparative study on natural super disintegrents and synthetic super disintegrents." International Journal of Advances in Scientific Research 1, no. 7 (2015): 313. http://dx.doi.org/10.7439/ijasr.v1i7.1821.

Full text

Abstract:

The aim of the present investigation is to formulate Enalapril maleate oral disintegrating tablet by using natural and synthetic superdisintegrents..ODTs may also be used to deliver drugs to the oral cavity, for local action or, in some cases, absorption across the oral mucosa, thereby avoiding first-pass hepatic metabolism and potentially increasing the rate and extent of uptake, and reducing undesirable metabolites. The objectives of the research work is to formulate oral disintegrating tablets of Enalapril maleate by using different super disintegrates(Natural, Synthetic) in different ratio

APA, Harvard, Vancouver, ISO, and other styles

36

Rai, Kritika, Vivek Jain, Sunil Kumar Jain, and Pushpendra Kumar Khangar. "Formulation and evaluation of taste masked oral disintegrating tablets of lornoxicam." Journal of Drug Delivery and Therapeutics 11, no. 5 (2021): 115–20. http://dx.doi.org/10.22270/jddt.v11i5.5124.

Full text

Abstract:

Orally disintegrating tablets (ODT) disintegrate quickly with saliva when administered into the oral cavity and taken without water or chewed. ODT are easy to take for children and the elderly, who may experience difficultly in taking ordinary oral preparations such as tablets, capsules, and powders. The ODT threes substantial benefits for the patient (or elder) who cannot swallow (Dysphagia), or who is not permitted water intake due to disease. The reason of the current research was to prepare taste masking oral disintegrating tablets of poorly soluble lornoxicam (LXM) by direct compression t

APA, Harvard, Vancouver, ISO, and other styles

37

M, K. Aneebuddin, and Kumar Prajwal. "Recent Trends in the Chemistry of Polymers used in Oral Drug Delivery Systems." Chemistry Research Journal 7, no. 6 (2022): 97–106. https://doi.org/10.5281/zenodo.11533254.

Full text

Abstract:

<strong>Abstract </strong>Tablet is one of the utmost chosen dosage forms administered orally<strong>.</strong> Disintegrants are substances added to tablets and some encapsulated preparations to encourage the breaking up of both tablet and capsule "slugs" into smaller fragments in an aquatic environment. This increases the surface area that is available and speeds up the release of the drug component. They increase moisture penetration and distribution of the tablet matrix. Tablet disintegration has attracted a lot of attention as an important stage in achieving rapid drug release. The concen

APA, Harvard, Vancouver, ISO, and other styles

38

Mahboob, Muhammad Bilal Hassan, Tehseen Riaz, Muhammad Jamshaid, Irfan Bashir, and Saqiba Zulfiqar. "Oral Films: A Comprehensive Review." International Current Pharmaceutical Journal 5, no. 12 (2016): 111–17. http://dx.doi.org/10.3329/icpj.v5i12.30413.

Full text

Abstract:

In the late 1970s, rapid disintegrating drug delivery system was developed as an alternative to capsules, tablets and syrups for geriatric and pediatric patients having problems in swallowing. To overcome the need, number of orally disintegrating tablets which disintegrate within one minute in mouth without chewing or drinking water were commercialized. Then later, oral drug delivery technology had been improved from conventional dosage form to modified release dosage form and developed recently rapid disintegrating films rather than oral disintegrating tablets. Oral disintegrating film or str

APA, Harvard, Vancouver, ISO, and other styles

39

Harish R, Lukkad, and Oswal Rajesh. "FORMULATION AND EVALUATION OF MODIFIED DISINTEGRATING SUSTAINED RELEASE TABLETS OF DICLOFENAC SODIUM." International Journal of Pharmaceutical Sciences and Medicine 6, no. 4 (2021): 52–66. http://dx.doi.org/10.47760/ijpsm.2021.v06i04.005.

Full text

Abstract:

Oral drug delivery is the largest and the oldest segment of the total drug delivery market. It is the fastest growing and most preferred route for drug administration. In oral drug delivery, the sustained release (SR) tablets maintains the desired drug concentration for prolong period of time, reduced 'see- saw' fluctuation, reduced total dose, improved efficiency in treatment. But many patients like paediatric, geriatric and also patients may have difficulty in swallowing (Dysphagia) find it difficult to swallow tablets and thus do not comply with prescription. This problem is overcome by for

APA, Harvard, Vancouver, ISO, and other styles

40

R. Venkatarao, K. Vinod Kumar, and B.Thangabalan. "Development and Characterization of Linagliptin Oral Disintegrating Tablets." International Journal of Allied Medical Sciences and Clinical Research 12, no. 1 (2024): 4–12. http://dx.doi.org/10.61096/ijamscr.v12.iss1.2024.4-12.

Full text

Abstract:

Linagliptin is an anti-diabetic drug used for the treatment of type 2 diabetes, it is belongs to the class of dpp-4 inhibitor. It has long half-life of about 8.6-23.9 hours and hence to achieve immediate therapeutic action it needs immediate release tablet formulation. Among the various techniques using superdisintegrants is a simple approach to formulate immediate release tablets. It undergoes an extensive hepatic first pass metabolism leads to low oral bioavailability (30%). ODT can overcome this problem through improving its bioavailability with an immediate drug release. In the present wor

APA, Harvard, Vancouver, ISO, and other styles

41

Pramod, Prakash Ronge* Dr. A.D. Shinde. "A REVIEW ON –FORMULATION AND IN-VITRO EVALUATION OF ORODISPERSIBLE TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 10991–1000. https://doi.org/10.5281/zenodo.3234069.

Full text

Abstract:

<em>Recent advances in novel drug delivery (NDDS) aims to enhance the safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance.</em><em> Orodispersible tablet is advanced and convenient drug delivery system, now days acquiring the most widely accepted dosage form. The recent advance in NDDS aimed for the development of dosage forms convenient to manufacturing and administration, immediate release and increased bioavailability.</em> <em>Orally disintegrating tablets are solid dosage forms containing drug tha

APA, Harvard, Vancouver, ISO, and other styles

42

Gupta, Sparsh, Rakesh Roshan Mali, and Vashali Goel. "Novel study in fast dissolving drug delivery system: a review." Indian Journal of Pharmaceutical and Biological Research 3, no. 01 (2015): 93–107. http://dx.doi.org/10.30750/ijpbr.3.1.14.

Full text

Abstract:

Novel drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and bio-chemical parameters pertinent to their performance. Despite tremendous advancements in drug delivery, the oral route remains the perfect route for the administration. Novel drug delivery system assists to achieve better patient compliance. Fast dissolving tablets are one of them.FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and ge

APA, Harvard, Vancouver, ISO, and other styles

43

Anusha, B. H.*1 Nagendra R.2 Venkatesh3 Hanumanthachar Joshi K.4. "Formulation And Evaluation of Fast Disintegrating Tablet of Betaxolol Hydrochloride Using Super Disintegrants." International Journal of Pharmaceutical Sciences 2, no. 11 (2024): 362–76. https://doi.org/10.5281/zenodo.14050550.

Full text

Abstract:

The study focused on developing a fast-disintegrating oral tablet of Betaxolol Hydrochloride aimed at treating hypertension through a direct compression method. Various formulations were tested using different concentrations of super disintegrants, with Microcrystalline cellulose serving as the diluent. Mannitol was utilized as a directly compressible diluent, while aspartame was chosen for its intense sweetness. Additionally, magnesium stearate and talc acted as lubricants, and aerosil was included to enhance flow properties. Pineapple flavor was added to improve the tablet's palatability. Th

APA, Harvard, Vancouver, ISO, and other styles

44

S., Aher Smita, Saudagar R. B., and Shinde Mayuri S. "REVIEW: FAST DISSOLVING TABLET." International Journal of Current Pharmaceutical Research 10, no. 2 (2018): 5. http://dx.doi.org/10.22159/ijcpr.2018v10i2.25876.

Full text

Abstract:

Fast dissolving tablets is one of the most widely accepted dosage forms and also most popular dosage form, especially for pediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Some solid dosage forms like tablets and capsules are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various

APA, Harvard, Vancouver, ISO, and other styles

45

ANKAJ, KAUNDAL, SHARMA TARUN, CHOUDHARY ARCHANA, SHARMA DEV RAJ, and THAKUR UPASANA. "A REVIEW ON ORAL DISINTEGRATING TABLETS." INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND BIO-SCIENCE 7, no. 4 (2018): 37–49. http://dx.doi.org/10.32395/ijprs.v7.i4.00003.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Wang, Jiu, Shunfang Liu, Minmei Lin, et al. "Fabricating Oral Disintegrating Tablets Without Disintegrant Using Powder-Based 3D Printing." Pharmaceutics 17, no. 4 (2025): 435. https://doi.org/10.3390/pharmaceutics17040435.

Full text

Abstract:

Background: Powder-based 3D printing, an advanced additive manufacturing technique, can produce oral disintegrating tablets (ODTs) without disintegrants, creating larger-pored tablets via layer-by-layer powder stacking for better water absorption than traditional tablets. Methods: This study focused on using powder-based 3D printing to fabricate clozapine-based ODTs. Through central composite design (CCD), the formulation of ODTs was optimized for rapid disintegration. Analytical techniques such as X-ray Powder Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), and Differential

APA, Harvard, Vancouver, ISO, and other styles

47

Shende, Mulchand A., and Kajal D. Chavan. "Formulation of Furosemide Oral Disintegrating Tablets Using Natural and Synthetic Superdisintegrants by SeDeM Expert Design System." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 55–63. http://dx.doi.org/10.22270/jddt.v9i6.3646.

Full text

Abstract:

SeDeM design expert technique used to evaluate the risks of poor flow of pharmaceutical powders under preformulation studies which reveals direct compression suitability and prepare robust composition of active pharmaceutical ingredient (API) and excipient in tablets formulation. The purpose of this study was to develop oral disintegrating tablets of Furosemide using different concentration of natural and synthetic superdisintegrants by means of SeDeM design technique. Oral disintegrating tablets (ODT) of Furosemide were prepared by direct compression technique using isolated banana powder and

APA, Harvard, Vancouver, ISO, and other styles

48

Shaikh, Siraj Nawaj* Shaikh Heena Kausar G. J. Khan Tajammul Khan. "INSIGHT IN TO USE OF CO PROCESS EXCIPIENTS IN ORAL DISINTEGRATING TABLETS-REVIEW ARTICLE." Indo American Journal of Pharmaceutical Sciences 04, no. 08 (2017): 2622–26. https://doi.org/10.5281/zenodo.858669.

Full text

Abstract:

Fast Disintegrating tablets have started gaining popularity and acceptance as new drug delivery systems, because t hey are easy to administer. Recent development in fast disintegrating technology mainly works to improve the disint egration quality of these delicate dosage forms without affecting their integrity. Oral disintegrating dosage form have facing many challenges which can be overcome by upcoming newly emerging approach of use of coprocess adujants in it. The developments or improvements in pharmaceutical process and equipments, particularly increase in production rates at low cost, le

APA, Harvard, Vancouver, ISO, and other styles

49

Sachin Sarashetti, Vikas Jain, Gowda D V, Pooja Mallya, and Satish Babu. "Recent developments in orally disintegrating mini tablets." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 3606–12. http://dx.doi.org/10.26452/ijrps.v11i3.2520.

Full text

Abstract:

Solid oral dosage forms are most suitable dosage forms; preferably tablets are widely accepted by people of different age groups. Mini tablets are tablets with a diameter equal to or smaller than 2–3 mm. Mini tablets are multiple unit dosage forms and are advantageous than pellets or any other oral dosage forms as they are easy to manufacture and stability problems are less. Many types of mini tablets are there like bio adhesive mini tablets, pH responsive mini tablets, gastro retentive mini tablets, paediatric mini tablets, oral disintegrating mini tablets. Current ODT developments meet multi

APA, Harvard, Vancouver, ISO, and other styles

50

Rahim, Mulani* Tushar Kore Shrirang Kharmate Saurabh Joshi Dipak Phalle Mrudula More Mrunal Mali Pratibha Shingade. "Mouth Dissolving Films: A Novel Approach to Oral Drug Delivery and Patient Compliance." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 128–32. https://doi.org/10.5281/zenodo.14960719.

Full text

Abstract:

Since mouth dissolving films are more convenient and user-friendly than other dosage forms like buccal tablets, sublingual tablets, and orally disintegrating tablets, they represent a novel approach to oral drug delivery systems. As a result, many pharmaceutical industries are becoming interested in mouth dissolving films. Due to the strong vascularization of the oral buccal mucosa, medications can be absorbed straight and enter the bloodstream without first-pass hepatic processing. Adequate flexibility, elasticity, softness, resistance to breaking, minimal disintegration time, and flavor comp

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!