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Journal articles on the topic 'Oral lichenoid reaction (OLR)'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ahmed, S., F. Aboobacker, H. Ummer, and I. Sundaram. "Lichenoid Reaction to Amalgam Restoration- A Case Report." Case Reports in Odontology 01, no. 02 (2014): 01–05. https://doi.org/10.5281/zenodo.15502.

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Oral mucosa is often a lone warrior subjected to face many diverse noxious opponents in the form of either hot or cold, acidic or alkaline substances, spiced or not so spicy foods. They may be also in constant contact with tobacco, alcohol, or other substances taken through the mouth or placed in the mouth like amalgam restorations. This paper reports a case of oral lichenoid reaction to amalgam and focuses on the local toxic effects of amalgam as dental restorations with particular reference to oral lichenoid reactions (lesions). 

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Giudice, Amerigo, Francesco Liborio, Fiorella Averta, Selene Barone, and Leonzio Fortunato. "Oral Lichenoid Reaction: An Uncommon Side Effect of Rituximab." Case Reports in Dentistry 2019 (November 6, 2019): 1–3. http://dx.doi.org/10.1155/2019/3154856.

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Oral lichenoid reactions (OLR) can be caused by systemic drug exposure. To the best of our knowledge, this is the second report describing a case of OLR induced by rituximab administration in a patient with a diagnosis of non-Hodgkin B-cell lymphoma. After 5 doses of rituximab, a typical pattern of OLP was identified with bilateral and symmetrical lesions on the buccal mucosa and on the right lingual margin. This temporal relationship suggested a probable association between oral lesions and drug therapy. The clinical diagnosis of a rituximab-induced OLR was confirmed by an incisional biopsy r

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Ramalingam, Suganya, Narasimhan Malathi, Harikrishnan Thamizhchelvan, Narasimhan Sangeetha, and Sharada T. Rajan. "Role of Mast Cells in Oral Lichen Planus and Oral Lichenoid Reactions." Autoimmune Diseases 2018 (2018): 1–5. http://dx.doi.org/10.1155/2018/7936564.

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Introduction. Oral lichen planus (OLP) is a chronic T cell mediated disease of oral mucosa, skin, and its appendages with a prevalence of 0.5 to 2.6% worldwide. Oral lichenoid reactions (OLR) are a group of lesions with diverse aetiologies but have clinical and histological features similar to OLP, thereby posing a great challenge in differentiating both lesions. Mast cells are multifunctional immune cells that play a major role in the pathogenesis of lichen planus by release of certain chemical mediators. Increased mast cell densities with significant percentage of degranulation have been obs

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Roychowdhury, Durba, Rudra Prasad Chatterjee, Sk Abdul Mahmud, Sudeshna Bagchi, and Arunit Chatterjee. "A Burning Issue on Oral Mucosal Diseases: Case Series with Review." Journal of Advances in Medicine and Medical Research 36, no. 8 (2024): 84–92. http://dx.doi.org/10.9734/jammr/2024/v36i85528.

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Oral Lichenoid Reaction (OLR) is a chronic inflammatory lesion of the oral mucosa that occurs as an allergic response to certain dental materials, medications and systemic diseases. The frequency of OLR in the general population has been documented to be very less. The clinical and histological features of OLR closely resemble those of Oral Lichen Planus (OLP), making it challenging to distinguish between the two clinically. OLRs might have a higher malignant potential than OLP. The diagnosis and treatment of OLR is very crucial as misdiagnosis may result in detrimental effects on the biophysi

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Jalal Hamza, Vaman, Ali Fakhree Alzubaidee, and Dindar Sharif Qurtas. "Clinical Study of Patients with Oral Lichenoid Processes Attending Khanzad Specialized Teaching Center and Erbil Dermatology Teaching Center." Diyala Journal of Medicine 19, no. 2 (2020): 96–106. http://dx.doi.org/10.26505/djm.19025460628.

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Background: Lichen planus is a common chronic inflammatory disease of the skin and mucous membranes. Oral Lichenoid Reactions (OLRs) comprise a group of lesions with different causative factors such as systemic medication, dental restorative materials, foods, or flavoring agents. Pathologists often group these conditions under the umbrella term of ‘lichenoid processes’. Objective: To provide prevalence and demographic distribution of Oral Lichen Planus (OLP) and OLR among a sample of patients. Patients and Methods: This cross-sectional study was conducted in the Khanzad Teaching Center and Erb

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Perez, Alexandre, Benjamin Lazzarotto, Jean-Pierre Carrel, and Tommaso Lombardi. "Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal." Dermatopathology 7, no. 1 (2020): 18–25. http://dx.doi.org/10.3390/dermatopathology7010004.

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Background: Lichen planus is a chronic mucocutaneous inflammatory disease. Oral manifestations are common, and may remain exclusive to the oral mucosa without involvement of the skin or other mucosae. A differential diagnosis includes oral lichenoid drug reactions. Allopurinol, which is the first line hypo-uricemic treatment, is often quoted as being a possible offending drug, though oral reactions have rarely been reported. Case presentation: We describe a 59-year-old male gout patient, successfully treated with allopurinol, who developed acute onset of oral lichenoid lesions, involving bilat

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Perez, Alexandre, Benjamin Lazzarotto, Jean-Pierre Carrel, and Tommaso Lombardi. "Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal." Dermatopathology 7, no. 2 (2020): 18–25. http://dx.doi.org/10.3390/dermatopathology7020004.

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Background: Lichen planus is a chronic mucocutaneous inflammatory disease. Oral manifestations are common, and may remain exclusive to the oral mucosa without involvement of the skin or other mucosae. A differential diagnosis includes oral lichenoid drug reactions. Allopurinol, which is the first line hypo-uricemic treatment, is often quoted as being a possible offending drug, though oral reactions have rarely been reported. Case presentation: We describe a 59-year-old male gout patient, successfully treated with allopurinol, who developed acute onset of oral lichenoid lesions, involving bilat

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8

Soorneedi, Neeharika, Mekala M. Sujatha, Tabassum Fatima, et al. "To Investigate the Involvement of Mast Cells in the Pathogenesis of Oral Lichen Planus and Oral Lichenoid Reactions." Journal of Pharmacy and Bioallied Sciences 16, Suppl 5 (2024): S4755—S4759. https://doi.org/10.4103/jpbs.jpbs_913_24.

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ABSTRACT Aim: Role of mast cells in the development of oral lichen planus (OLP) and oral lichenoid reactions (OLR). Material and Methods: The tissue slices used in this investigation were obtained from the archives of the Department of Oral Pathology and were formalin-fixed and embedded in paraffin. The sections were obtained from 40 cases of OLP that were identified by histological examination, as well as 40 cases of OLR. Twenty buccal mucosa samples were obtained from individuals who showed no mouth lesions and did not participate in any oral practices. The study samples were subjected to ha

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9

Shaikh, Uffra, Swagata Tambe, Kirti Jangid, and Prashant Patil. "Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome." Indian Journal of Paediatric Dermatology 26, no. 2 (2025): 125–28. https://doi.org/10.4103/ijpd.ijpd_1_25.

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Lichenoid drug reactions (LDRs) are a type of cutaneous adverse drug reaction that clinically resembles lichen planus and demonstrates lichenoid tissue reaction on histopathology. These have been implicated by various topical, oral, and injectable medications. Noonan’s syndrome (NS) is an autosomal dominant disorder with skeletal deformity, particularly short stature as a common feature for which growth hormone (GH) therapy is effective. Here, we present a 16-year-old male with NS who developed lichenoid dermatitis on initiation of injectable GH therapy and showed remission with oral apremilas

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Saepoo, Jirayu, Duangporn Kerdpon, and Kanokporn Pangsomboon. "Malignant Transformation in Oral Lichen Planus and Lichenoid Reactions in Southern Thai Population." Oral Sciences Reports 44, no. 3 (2023): 27–34. http://dx.doi.org/10.12982/osr.2023.014.

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Objectives: This study aimed to determine the prevalence of malignant transformation (MT) and the incidence rate of oral squamous cell carcinoma (OSCC) in oral lichen planus (OLP) and oral lichenoid reaction (OLR) patients from southern Thailand. Methods: This hospital-based retrospective cohort study comprised OLP/OLR patients who were treated between January 2016 and December 2022. Data on the general characteristics, clinical manifestations and laboratory investigations were obtained from the hospital records and analyzed. Descriptive and analytical statistics were performed to assess the d

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Samuel Ebele Udeabor. "Expression of CD83 in Gingival Lesions: Diagnostic Potential in Oral Lichen Planus and Oral Lichenoid Reactions." Future Dental Research 2, no. 2 (2024): 12–16. https://doi.org/10.57238/fdr.2024.152576.1009.

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Oral lichen planus (OLP) and oral lichenoid reactions (OLR) are chronic immune-mediated conditions affecting the oral mucosa, often involving the gingiva. Their overlapping clinical and histopathological features make accurate diagnosis challenging. CD83, a transmembrane glycoprotein expressed on mature dendritic cells, is a key regulator of immune responses through its role in antigen presentation and T-cell activation. This study evaluates the expression of CD83 in gingival tissues affected by OLP and OLR, aiming to establish its diagnostic potential.Seventy-two gingival tissue samples, incl

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Petruzzi, Massimo, Fedora della Vella, Guglielmo Campus, Dario Di Stasio, and Dorina Lauritano. "Lingual Lichenoid Lesion Due to Dental Amalgam Fillings: Case Report and Clinical Considerations." Applied Sciences 12, no. 24 (2022): 12895. http://dx.doi.org/10.3390/app122412895.

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Oral white lesions are quite common clinical conditions in clinical dental practice. They can be an expression of different diseases, so it is crucial to achieve a correct diagnosis to start an adequate treatment. However, differential diagnosis is not always easy because the clinical appearance of oral white lesions is often similar and non-pathognomonic. We report on a 42-year-old Caucasian woman who complained of a chronic white patch on the left border of her tongue. A provisional diagnosis of oral hairy leukoplakia was made, but the patient was HIV-negative and not immunocompromised. A pa

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Kan, Siyue, Hongjin Ren, Zhiqin Gao, et al. "Lichenoid drug eruption on the lower lip caused by anti-PD-1 monoclonal antibody: a case report and literature review." Immunotherapy 13, no. 17 (2021): 1373–78. http://dx.doi.org/10.2217/imt-2021-0234.

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Anti-PD-1/PD-L1 monoclonal antibodies result in a unique spectrum of side effects, widely known as immune-related adverse events. Toripalimab is an anti-PD-1 monoclonal antibody used for the treatment of some cancers. Here we report the first case, to our knowledge, of oral lichenoid drug reaction triggered by toripalimab. A 78-year-old man who was diagnosed with systemic metastatic prostate cancer presented with ulcers on the lower lip after the fifth cycle of toripalimab. We diagnosed him with oral lichenoid drug reaction based on clinical manifestation, histopathological findings and the hi

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Nalamliang, Napat, Nichruethai Tangnantachai, and Kobkan Thongprasom. "Medications in Thai Patients with Oral Lichen Planus, Oral Lichenoid Drug Reaction and Glossitis." International Journal of Experimental Dental Science 3, no. 2 (2014): 73–76. http://dx.doi.org/10.5005/jp-journals-10029-1075.

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ABSTRACT Introduction Medications have been widely used in the dental patients for the treatment of their systemic diseases. In fact, those drugs have some side-effects to many organs and also the oral cavity. The aim of our study was to investigate the relationship between medications and oral lichen planus (OLP), oral lichenoid drug reaction (OLDR) and glossitis (GT) in Thai patients. Materials and methods One hundred and thirty-eight cases of Thai patients were included in this study. Medical records of all cases with oral lesions and symptoms referred to the oral medicine clinic during 200

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Patel, Jaimish S., Vishalkumar K. Vadgama, Palak C. Sanghani, and Trunali C. Navadiya. "Telmisartan-induced lichenoid drug eruption: a case report." International Journal of Research in Medical Sciences 13, no. 6 (2025): 2644–46. https://doi.org/10.18203/2320-6012.ijrms20251662.

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Lichenoid drug eruption (LDE) is a rare adverse reaction to various medications, including antihypertensives like telmisartan. Early identification and withdrawal of the offending agent are key to management. A 52-year-old hypertensive male on telmisartan developed pruritic, violaceous lesions over the scalp and extremities, later spreading to the face, neck, and back, with oral involvement. Initial treatment offered partial relief. A diagnosis of telmisartan-induced lichenoid eruption was made, and the drug was replaced with amlodipine. Betamethasone mini-pulse therapy and azathioprine were i

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16

Arirachakaran, Pratanporn, Mattana Hanvanich, Piyanad Kuysakorn, and Kobkan Thongprasom. "Antiretroviral Drug-Associated Oral Lichenoid Reaction in HIV Patient: A Case Report." International Journal of Dentistry 2010 (2010): 1–4. http://dx.doi.org/10.1155/2010/291072.

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Antiretroviral therapy has changed the course of HIV disease and improved quality of life in HIV patients. Incidence of an oral lichenoid drug reaction induced by zidovudine is not common. Once it occurs, it affects a patient's well being, in particular their oral functions. Here we report the first case of a 34-year-old Thai man with painful erosive lesions involving the lip and buccal mucosa. Treatment with topical fluocinolone acetonide 0.1% alleviated the patient's oral pain, but it was not until the subsequent withdrawal of zidovudine that the patient showed improvement and resolution of

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Hirota, Silvio, Norberto Sugaya, and Dante Migliari. "Oral lichenoid contact reaction to amalgam occurring as a leukoplakia-like lesion: a case report." International Journal of Research in Dermatology 6, no. 1 (2019): 115. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20195685.

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<p class="abstract">This article reports a case of oral lichenoid contact reaction (OLCR) in which a bilateral lesion involving the buccal mucosa was observed. Its relevance lies on that the lesions could be misdiagnosed as an oral leukoplakia, since they showed a typical feature of a homogeneous white plaque; however, fortunately, this misjudgement was spared because one of the lesions, on the right-buccal side, was in direct contact with an amalgam filling. Hence, the suspicion of mucosal contact reaction was made and the patient successfully treated by amalgam replacement. Comments on

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18

Yamashita, Aya, Eijiro Akasaka, Hajime Nakano, and Daisuke Sawamura. "Pembrolizumab-Induced Lichen Planus on the Scalp of a Patient with Non-Small-Cell Lung Carcinoma." Case Reports in Dermatology 13, no. 3 (2021): 487–91. http://dx.doi.org/10.1159/000519486.

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A 67-year-old man with non-small-cell lung carcinoma was referred to our department because of a pruritic rash on his head and upper extremities. Prior to the development of the rash, he had received 4 cycles of combination therapy with pemetrexed, carboplatin, and pembrolizumab, followed by 2 cycles of pembrolizumab monotherapy. On physical examination, violaceous scaly erythema grouped on his scalp and upper extremities. Histologically, the scalp lesions demonstrated irregular acanthosis that formed a characteristic saw-tooth appearance with hypergranulosis and typical lichenoid tissue react

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Yura, Yoshiaki, and Masakazu Hamada. "Oral Immune-Related Adverse Events Caused by Immune Checkpoint Inhibitors: Salivary Gland Dysfunction and Mucosal Diseases." Cancers 14, no. 3 (2022): 792. http://dx.doi.org/10.3390/cancers14030792.

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Conventional chemotherapy and targeted therapies have limited efficacy against advanced head and neck squamous cell carcinoma (HNSCC). The immune checkpoint inhibitors (ICIs) such as antibodies against CTLA-4, PD-1, and PD-L1 interrupt the co-inhibitory pathway of T cells and enhance the ability of CD8+ T cells to destroy tumors. Even in advanced HNSCC patients with recurrent diseases and distant metastasis, ICI therapy shows efficiency and become an effective alternative to conventional chemotherapy. However, as this therapy releases the immune tolerance state, cytotoxic CD8+ T cells can also

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Yacquelynes, Corona Hechavarria Y*, Teresa Lao Rivera Maria, Olabachea Varona Leroy, Esema Christopher, and Ahmad Ashfaq. "Cutaneous Tuberculosis: Issues in the Diagnose." International Journal of Clinical and Medical Cases (ISSN:2517-7346) 3, no. 5 (2020): 1–3. https://doi.org/10.31021/ijcmc.20203150.

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<strong>Abstract</strong> Liquenscrofulosorum, also known as tuberculosis cutis lichenoides, is a rare tuberculid that presents as lichenoid eruptions of minute papule, is an uncommon disease and easily misdiagnosed. The lesions are usually asymptomatic, closely grouped, skin colored to reddish-brown papules, often perifollicular. The eruption usually is associated with strongly positive tuberculin reaction. Diagnosis of the lesions can be difficult, as they resemble many other dermatological conditions that are often primarily considered. We report a case of lichen scrofulosorum in an adult m

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Jisha Susan Jose and Yeshavant G. "Adverse reactions of herbal drug: a case report of hepatitis, oral mucositis, and lichenoid reactions." World Journal of Advanced Research and Reviews 19, no. 1 (2023): 717–20. http://dx.doi.org/10.30574/wjarr.2023.19.1.1399.

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Herbal medicine products are widely used as a popular therapeutic option worldwide. However, it is unfounded to assume that they are entirely free from side effects. In this particular case report, we are discussing a 40-year-old male patient who was diagnosed with herbal drug-induced hepatitis and oral mucositis, along with lichenoid reactions secondary to drug reaction. The patient was advised to take oral steroids and moisturizing cream. Initially, the patient was admitted under the Department of ENT and was later transferred to the Department of Medicine due to severe thrombocytopenia. Nec

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Jisha, Susan Jose, and G. Yeshavant. "Adverse reactions of herbal drug: a case report of hepatitis, oral mucositis, and lichenoid reactions." World Journal of Advanced Research and Reviews 19, no. 1 (2023): 717–20. https://doi.org/10.5281/zenodo.10254803.

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Herbal medicine products are widely used as a popular therapeutic option worldwide. However, it is unfounded to assume that they are entirely free from side effects. In this particular case report, we are discussing a 40-year-old male patient who was diagnosed with herbal drug-induced hepatitis and oral mucositis, along with lichenoid reactions secondary to drug reaction. The patient was advised to take oral steroids and moisturizing cream. Initially, the patient was admitted under the Department of ENT and was later transferred to the Department of Medicine due to severe thrombocytopenia. Nec

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23

Marcu (Selaru), Corina Andreea, Ioanina Parlatescu, Serban Tovaru, Carmen Larisa Nicolae, Mariana Costache, and Mihaela Tovaru. "Lichen Planus of the Lip—Case Series and Review of the Literature." Medicina 60, no. 6 (2024): 987. http://dx.doi.org/10.3390/medicina60060987.

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Background and Objectives: Lichen planus of the lip (LPL) is a chronic inflammatory condition that resembles actinic cheilitis, discoid lupus erythematosus, graft-versus-host disease, and lichenoid reaction to dental materials or drugs. The purpose of this study was to conduct a literature review on lichen planus lip involvement and to report a retrospective observational study that characterises and explores the clinical, histopathological, and evolution of the lesions in a group of patients with unique involvement of LPL. Materials and Methods: Clinical data of patients diagnosed with LPL wa

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Gey, Aurelia, Thomas Jouary, Christine Mateus, Caroline Robert, Gerard Perro, and Brigitte Milpied. "Vemurafenib-associated bullous DRESS syndrome: A very severe cutaneous reaction." Journal of Clinical Oncology 31, no. 15_suppl (2013): e20041-e20041. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e20041.

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e20041 Background: Vemurafenib, a selective BRAF inhibitor, has recently demonstrated improved overall survival in metastatic melanoma. Frequent cutaneous side effects have been reported with vemurafenib, mostly non severe. We report the first case of bullous DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) related to vemurafenib. Methods: Case report: A 69 year old man presented with a BRAF mutated multimetasatic melanoma. Vemurafenib, 960 mg orally twice daily, was started in August 2012. Treatment was discontinued 1 month later because of a grade 2 rash and nausea. Tre

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Sunith, M., M. Ramesh Kumar, K. Shoba, and S. Jayasree. "Amalgam associated oral lichenoid reaction." Journal of Conservative Dentistry 9, no. 4 (2006): 148. http://dx.doi.org/10.4103/0972-0707.42317.

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LIND, PETTER O., BJÖRN HURLEN, TORSTEIN LYBERG, and EIGIL AAS. "Amalgam-related oral lichenoid reaction." European Journal of Oral Sciences 94, no. 5 (1986): 448–51. http://dx.doi.org/10.1111/j.1600-0722.1986.tb01786.x.

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Amine, Ennaciri Mohamed, Basri Ghita, Zemmez Youssef, et al. "Metformin Induced Lichenoïd Drug Eruption." Scholars Journal of Medical Case Reports 12, no. 12 (2024): 2048–51. https://doi.org/10.36347/sjmcr.2024.v12i12.011.

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Cutaneous lichenoid drug eruptions are rare adverse drug reactions reminiscent of lichen planus. The most frequently reported culprit drugs are Checkpoint inhibitors, tyrosine kinase inhibitors and TNF-α inhibitors, but other drugs can also be responsible. This case-report is about a 49-year-old woman with a history of type 2 diabetes. She started taking metformin 160 weeks before the onset of a pruritic lichenoid rash on the trunk and limbs, of which the histopathology was in favor of an adverse cutaneous lichenoid drug eruption caracterized by the presence of eosinophilic polynuclei in the p

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Bronny, Andrew T., and Robert M. Thies. "Oral mucosal lichenoid reaction to sulfamethoxazole." Special Care in Dentistry 10, no. 2 (1990): 55–57. http://dx.doi.org/10.1111/j.1754-4505.1990.tb01197.x.

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Saraneva, Orvokki, Jussi Furuholm, Jaana Hagström, et al. "Oral Potentially Malignant Disorders and Candida in Oral Tongue Squamous Cell Carcinoma Patients." Dentistry Journal 11, no. 7 (2023): 170. http://dx.doi.org/10.3390/dj11070170.

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This retrospective study addressed the role of oral potentially malignant disorders and the presence of intraepithelial Candida hyphae in the carcinogenesis of the oral tongue squamous cell carcinoma and its association with smoking, alcohol consumption, and oral inflammatory burden. The medical records of 183 subjects diagnosed with oral tongue squamous cell carcinoma at the Helsinki University Hospital were investigated. Preceding oral lichen planus, lichenoid reaction, and leukoplakia diagnosis were recorded. Further, the data on Candida hyphae in histological samples as an indicator of ora

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Apsari, Widya. "OBAT ANTIDIABETIK MEMICU TERBENTUKNYA ORAL LICHENOID REACTION." Jurnal Ilmiah dan Teknologi Kedokteran Gigi 14, no. 2 (2018): 75. http://dx.doi.org/10.32509/jitekgi.v14i2.635.

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Rongga mulut dapat menjadi salah satu target dari sejumlah kelainan yang berkembang dari efek samping obat. Secara teori, semua obat mempunyai efek samping, yang meliputi diskrasia darah, perubahan respon imun, reaksi hipersensitif atau tertunda, dan kecenderungan untuk perubahan onkogenik. Efek ini dapat menimbulkan manifestasi oral, dan mucositis yang dapat terjadi baik secara langsung atau sekunder dari penggunaan obat.

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DA SILVA, INGRID CARLA GUEDES, ADRIANA MACHADO ZARZAR, RAYLANE FARIAS DE ALBUQUERQUE, et al. "VENLAFAXINE CHLORIDRATE-ORAL LICHENOID REACTION: CASE REPORT." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 129, no. 1 (2020): e71. http://dx.doi.org/10.1016/j.oooo.2019.06.281.

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Zainullin, T. A., E. V. Ivanova, D. A. Moiseev, et al. "Features of differential diagnosis of lichen planus and lichenoid reaction of the oral cavity: histopathological analysis." Clinical Dentistry (Russia) 28, no. 1 (2025): 18–24. https://doi.org/10.37988/1811-153x_2025_1_18.

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Lichen planus is a chronic autoimmune skin-mucosal disease that often affects the oral cavity and can affect the esophagus, the mucous membrane of the genitals, the skin and its appendages. Lichenoid reactions are considered as lesions clinically similar to lichen planus erythematosus, but differing in pathogenesis, etiology and, consequently, treatment approaches. The main provoking factors of lichenoid reactions are medicines and dental materials. The aim of the study was to identify histopathological differences between lichen planus erythematosus and lichenoid reactions of the oral cavity

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Pergolini, Daniele, Mohamed Mohsen, Federica Basile, et al. "Clinical Correlation Between Antihypercholesterolemic and Antihypertensive Drugs with Oral Lichenoid Lesions: Literature Review and Preliminary Retrospective Analysis." Applied Sciences 15, no. 7 (2025): 3750. https://doi.org/10.3390/app15073750.

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Despite extensive research, the exact cause of oral lichenoid lesions remains unknown. The chronic inflammatory tissue reaction mediated by T cells is the basis of the etiological process. However, oral lichenoid lesions often occur in the presence of certain drugs. Our aim was to conduct a preliminary retrospective study to assess the correlation between the administration of statins or HMG-inhibitor CoA reductase, which are commonly used for treating hypercholesterolemia, and the sartans or blockers of the angiotensin II receptor, which are used for treating hypertension, in relation to the

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Barnabé, Luan Éverton Galdino, Walter Gleybson Antas De Morais, Pâmela De Medeiros Dantas, et al. "ORAL LICHEN PLANUS AND ORAL LICHENOID REACTION: A MORPHOLOGICAL STUDY." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 134, no. 3 (2022): e215. http://dx.doi.org/10.1016/j.oooo.2022.01.673.

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Agha-Hosseini, Farzaneh, Mohammad Samami, Fatemeh Tavakol, and Elahe Ghasemzadeh Hoseini. "Oral Lichen Planus or Oral Lichenoid Reaction? A Literature Review." Journal of Islamic Dental Association of IRAN 31, no. 1 (2019): 40–57. http://dx.doi.org/10.30699/jidai.31.1.7.

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Laksitasari, Anindita, Ridhofar Akbar Khusnul Abdillah, Rinawati Satrio, et al. "Reaksi Likenoid Sebagai Akibat Penggunaan Obat Antihipertensi pada Rongga Mulut." STOMATOGNATIC - Jurnal Kedokteran Gigi 20, no. 1 (2023): 8. http://dx.doi.org/10.19184/stoma.v20i1.38591.

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A lichenoid reaction is commonly finding in the oral cavity. A lichenoid reaction may be caused by systemic drugs. Among the drugs are antihypertensive drugs. The aim of this study is to know the treatment of patient with oral lichenoid reaction. Male patient came into RSGM Unsoed complaining of white patches on the right gums near 3rd molar three months ago. The white patches were painless and approximately 0.5 in diameter. Anamnesis was presenting patients is conducted and has been shown that they take 6 years of antihypertensive drugs and are prescribed by their own physician in the city of

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Bastos, Daniela B., Ingrid S. Santos, Vitor B. Valente, et al. "Lollipop-induced oral lichenoid reaction in a child." International Journal of Paediatric Dentistry 26, no. 6 (2016): 486–89. http://dx.doi.org/10.1111/ipd.12240.

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Brown, Ronald S., and Andre A. Farquharson. "A topical imiquimod-induced oral mucosal lichenoid reaction." Journal of the American Dental Association 145, no. 11 (2014): 1141–45. http://dx.doi.org/10.14219/jada.2014.88.

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de OLIVEIRA, Cecília Raquel Guimarães, Milena Moraes de Oliveira LENZA, Felipe Mesquita ARAÚJO, et al. "ORAL LICHENOID REACTION ASSOCIATED WITH PAROXETINE HYDROCHLORIDE USE." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 137, no. 6 (2024): e201. http://dx.doi.org/10.1016/j.oooo.2023.12.265.

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Lim, Davin S., and James Muir. "Oral Lichenoid Reaction to Imatinib (STI 571, Gleevec)." Dermatology 205, no. 2 (2002): 169–71. http://dx.doi.org/10.1159/000063899.

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Pigatto, Paolo D., Gianpaolo Bombeccari, Francesco Spadari, and Gianpaolo Guzzi. "Oral Lichenoid Reaction, Dental Amalgam, and Tin Allergy." American Journal of Dermatopathology 33, no. 4 (2011): 414–15. http://dx.doi.org/10.1097/dad.0b013e3181e7ce49.

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Bhattacharyya, Indraneel, Hardeep Chehal, and Cesar Migliorati. "Severe oral erosive lichenoid reaction to pembrolizumab therapy." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 130, no. 5 (2020): e301-e307. http://dx.doi.org/10.1016/j.oooo.2020.06.014.

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DOS SANTOS JÚNIOR, JÁCIO KLEBER, CAMILA MARIA BEDER RIBEIRO, STEFÂNIA JERONIMO FERREIRA, et al. "Oral Lichenoid Reaction to Amalgam: 2 Case Reports." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 120, no. 2 (2015): e36. http://dx.doi.org/10.1016/j.oooo.2015.02.133.

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Enomoto, Y., H. Nakatani, S. Kondo, T. Kasai, and Y. Tsuchiya. "Drug-induced oral lichenoid reaction during nivolumab therapy." International Journal of Oral and Maxillofacial Surgery 48, no. 4 (2019): 488–91. http://dx.doi.org/10.1016/j.ijom.2018.07.025.

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Do Prado, RenataFalchete, LucianaSassa Marocchio, and RenataCallestini Felipini. "Oral lichen planus versus oral lichenoid reaction: Difficulties in the diagnosis." Indian Journal of Dental Research 20, no. 3 (2009): 361. http://dx.doi.org/10.4103/0970-9290.57375.

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Jain, Neetu, Abhishek Dhindsa, Shalini Garg, Nilika Choupal, and Sumit Singla. "Oral drug-induced lichenoid reaction in pediatric age group." Saudi Journal of Oral Sciences 5, no. 2 (2018): 130. http://dx.doi.org/10.4103/sjos.sjoralsci_30_18.

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Kadam, Nilima S., Rahul A. Patil, Abhijit N. Gurav, et al. "Duloxetine Hydrochloride-Induced Oral Lichenoid Reaction: A Case Report." Medical Principles and Practice 24, no. 4 (2015): 394–97. http://dx.doi.org/10.1159/000430887.

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Shah, K. M., M. R. Agrawal, S. A. Chougule, and J. D. Mistry. "Oral lichenoid reaction due to nickel alloy contact hypersensitivity." Case Reports 2013, may08 1 (2013): bcr2013009754. http://dx.doi.org/10.1136/bcr-2013-009754.

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Handley, T. P. B., and G. R. Ogden. "Dyskeratosis congenita: oral hyperkeratosis in association with lichenoid reaction." Journal of Oral Pathology and Medicine 35, no. 8 (2006): 508–12. http://dx.doi.org/10.1111/j.1600-0714.2006.00434.x.

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Yamanaka, Shigeki, Kazumasa Nakao, Aya Ninomiya, et al. "A case of oral lichenoid reaction during nivolumab therapy." Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 32, no. 6 (2020): 521–24. http://dx.doi.org/10.1016/j.ajoms.2020.07.018.

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