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Journal articles on the topic 'Oral mucosa Keratinization'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Nguyen, Ha Thi Thu, Mitsuaki Ono, Emilio Satoshi Hara, et al. "Type XVIII Collagen Modulates Keratohyalin Granule Formation and Keratinization in Oral Mucosa." International Journal of Molecular Sciences 20, no. 19 (2019): 4739. http://dx.doi.org/10.3390/ijms20194739.

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Epithelial keratinization involves complex cellular modifications that provide protection against pathogens and chemical and mechanical injuries. In the oral cavity, keratinized mucosa is also crucial to maintain healthy periodontal or peri-implant tissues. In this study, we investigated the roles of type XVIII collagen, a collagen-glycosaminoglycan featuring an extracellular matrix component present in the basement membrane, in oral mucosal keratinization. Histological analysis of keratinized and non-keratinized oral mucosa showed that type XVIII collagen was highly expressed in keratinized m

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2

Shimada, Katsumitsu, Takanaga Ochiai, and Hiromasa Hasegawa. "Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus." Journal of International Medical Research 46, no. 11 (2018): 4722–30. http://dx.doi.org/10.1177/0300060518798261.

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Objective Oral lichen planus (OLP) characterized by interface mucositis frequently shows hyper-keratinization. To clarify mechanisms of excess keratinization, we investigated key molecules for cornified cell envelope (CE). Methods Involucrin (IVL), loricrin (LOR), transglutaminase 1 (TGase 1) and transglutaminase 3 (TGase 3) were immunohistochemically examined in 20 specimens of OLP; five specimens of buccal mucosa served as controls. Subsequently, the data were statistically analyzed. Results IVL in OLP was localized in the cell membrane, in contrast to its localization in the cytoplasm in co

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3

Lukandu, Ochiba Mohammed, Lionel Sang Koech, and Paul Ngugi Kiarie. "Oral Lesions Induced by Chronic Khat Use Consist Essentially of Thickened Hyperkeratinized Epithelium." International Journal of Dentistry 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/104812.

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Objectives.The habit of khat chewing is prevalent in many Middle Eastern and African cultures and has been associated with various adverse conditions in humans. This study aimed to describe histological changes induced by chronic khat chewing on the buccal mucosa.Methods.Biopsies of the buccal mucosa from 14 chronic khat chewers, 20 chronic khat chewers who also smoked tobacco, and 8 nonchewers were compared for epithelial thickness, degree and type of keratinization, and connective tissue changes.Results.Tissues from khat chewers depicted abnormal keratinization of the superficial cell layer

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4

Lawall, Melaine de Almeida, and Marcelo Macedo Crivelini. "PCNA and p53 expression in oral leukoplakia with different degrees of keratinization." Journal of Applied Oral Science 14, no. 4 (2006): 276–80. http://dx.doi.org/10.1590/s1678-77572006000400012.

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Leukoplakias are oral lesions that may have many clinical and histological aspects and they are usually associated with malignancy when dysplastic alterations are shown. However, these transformations may occur in non-dysplastic lesions that show harmless clinical aspect. For this reason, the proposal was to study the p53 and PCNA immunohistochemical expression in non-dysplastic leukoplakias, trying to correlate the results only with the epithelial keratinization degree. For this, 24 leukoplakias degrees I, II and III of Grinspan were used, all of them located in oral mucosa. Most of the leuko

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5

Manoja, K. G. D., B. S. M. S. Siriwardena, P. R. Jayasooriya, D. J. L. Siriwardane, and W. M. Tilakaratne. "A Rare Clinical Presentation of Intraoral Darier's Disease." Case Reports in Pathology 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/181728.

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Darier's disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules primarily affecting seborrheic areas on the head, neck, thorax, and less frequently the oral mucosa. When oral manifestations are present, the palatal and alveolar mucosae are primarily affected. They usually asymptomatic and are discovered in routine dental examination. Histologically, the lesions present as suprabasal clefts in th

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6

Ferizi, Mybera, Antigona Begolli-Gerqari, Bostjan Luzar, Fisnik Kurshumliu, and Mergita Ferizi. "A Rare Clinical Presentation of Darier’s Disease." Case Reports in Dermatological Medicine 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/419797.

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Darier’s disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity. Its manifestation appears as hyperkeratotic papules, primarily affecting seborrheic areas on the head, neck, and thorax and less frequently on the oral mucosa. When oral manifestations are present, the palatal and alveolar mucosae are primarily affected. They are usually asymptomatic and are discovered in routine dental examination. Histologically, the lesions are presented as suprab

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7

Syafriadi, Mei, Hiroko Ida-Yanemochi, Terué Ikarashi, et al. "Carcinoma in-situ of the Oral Mucosa has a Definite Tendency towards Keratinization." Oral Medicine & Pathology 8, no. 2 (2003): 43–44. http://dx.doi.org/10.3353/omp.8.43.

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8

Landgraf, Ana Carolina Machado, Angélica Reinheimer, Júlio Cezar Merlin, Soraya de Azambuja Berti Couto, and Paulo Henrique Couto Souza. "Mechanical Ventilation and Cytopathological Changes in the Oral Mucosa." American Journal of Critical Care 26, no. 4 (2017): 297–302. http://dx.doi.org/10.4037/ajcc2017218.

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BackgroundThe oral mucosa is an important defense barrier to penetration of microorganisms. Thus, changes in the oral epithelium might indicate risk for infection in intensive care patients receiving mechanical ventilation.ObjectiveTo evaluate the oral mucosa of intensive care patients who did or did not receive mechanical ventilation by using liquid-base exfoliative cytology.MethodsThe sample consisted of 3 groups: 27 patients admitted to intensive care during a 7- to 14-day period who received mechanical ventilation, 29 patients admitted during the same period who did not receive mechanical

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9

Webber, LP, ACA Pellicioli, AS Magnusson, et al. "Nuclear changes in oral mucosa of alcoholics and crack cocaine users." Human & Experimental Toxicology 35, no. 2 (2015): 184–93. http://dx.doi.org/10.1177/0960327115579430.

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The effects of drugs of abuse on oral mucosa are only partly understood. The aims of the present study were to: (1) evaluate the frequency of nuclear changes in normal-appearing oral mucosa of alcoholics and crack cocaine users and (2) assess their association with cell proliferation rate. Oral smears were obtained from the border of the tongue and floor of the mouth of 26 crack cocaine users (24 males and 2 females), 29 alcoholics (17 males and 12 females), and 35 controls (17 males and 18 females). Histological slides were submitted to Feulgen staining to assess the frequency of micronuclei

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10

Premachandra, D. J., B. Woodward, C. M. Milton, R. J. Sergeant, and J. W. Fabre. "Treatment of chronic mastoiditis by grafting of mastoid cavities with autologous epithelial layers generated by in vitro culture of buccal epithelium." Journal of Laryngology & Otology 105, no. 6 (1991): 413–16. http://dx.doi.org/10.1017/s0022215100116172.

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AbstractAutologous cultured epithelial layers were established from biopsies from the mucosa of the cheek, a nonkeratinizing region of the oral cavity. These were grafted to the unepithelialized mastoid cavities of nine patients with chronic mastoiditis and severe otorrhoea varying from two to 30 years' duration. All procedures were performed on an out-patient basis, with no anaesthesia except for topical anaesthesia for the mucosal biopsy. In seven of the patients the grafts took well, with complete resolution of the otorrhoea for a minimum follow-up period of eight months. In one patient the

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11

Vuckovic, Nada, Marija Bokor-Bratic, and Dejan Vuckovic. "Histological characteristics of oral leukoplakia." Medical review 57, no. 3-4 (2004): 140–43. http://dx.doi.org/10.2298/mpns0404140v.

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Introduction Leukoplakia (LKP) is defined as a white patch or plaque on the mucosa of oral cavity, vulva, vagina etc., which cannot be removed and cannot be clinically or microscopically explained by presence of a disease. LKP is included in the group of lesions with malignant potential. Microscopic characteristics Basic microscopic characteristics of oral LKP include hyperkeratosis of ortho- or parakeratotic type and acanthosis of the epithelium, with various degrees of chronic inflammatory infiltrates in lamina propria. Also, various degrees of epithelial dysplasia may occur. Some of the mos

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12

Al-Eryani, K., J. Cheng, S. Maruyama, M. Yamazaki, T. Kobayashi, and T. Saku. "8537 Hemophagocytosis-related keratinization in squamous cell carcinoma and carcinoma in-situ of the oral mucosa." European Journal of Cancer Supplements 7, no. 2 (2009): 481. http://dx.doi.org/10.1016/s1359-6349(09)71628-3.

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13

Borzenok, Sergey A., Boris E. Malyugin, Maxim Y. Gerasimov, Dmitriy S. Ostrovskiy, and Anna V. Shatskikh. "Feeder-Free Cell Culture of Labial Oral Mucosal Epithelium for Tissue-Engineering and Regenerative Medicine." Annals of the Russian academy of medical sciences 75, no. 5 (2020): 561–70. http://dx.doi.org/10.15690/vramn1357.

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Background.The cultured cheek mucosa epithelium (buccal epithelium, BE) is used for autologous transplants generation and tissue engineering. An alternative source of cells for these purposes may be the lip mucosa, covered, like BE, with non-keratinized stratified squamous epithelium, but with some histological distinctions.Aims to characterize the human lip mucosa as a promising source of epithelial cells for autologous transplantation and tissue engineering.Methods.Scrapings of the lip, cheek, and gum mucosa from five healthy volunteers were analyzed by cytofluorimetry to determine the level

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14

Murakami, H., K. Okamura, S. Aoki, R. Sakagami, and J. Yamazaki. "Association of caspase-14 and filaggrin expression with keratinization of the oral mucosa and reconstruction culture rat models." Journal of Periodontal Research 49, no. 6 (2013): 703–10. http://dx.doi.org/10.1111/jre.12152.

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15

Vo, Phuc Thi-Duy, Sun Shim Choi, Hae Ryoun Park, Ahreum Lee, Sung-Hee Jeong, and Youngnim Choi. "Gene signatures associated with barrier dysfunction and infection in oral lichen planus identified by analysis of transcriptomic data." PLOS ONE 16, no. 9 (2021): e0257356. http://dx.doi.org/10.1371/journal.pone.0257356.

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Oral lichen planus (OLP) is one of the most prevalent oral mucosal diseases, but there is no cure for OLP yet. The aim of this study was to gain insights into the role of barrier dysfunction and infection in OLP pathogenesis through analysis of transcriptome datasets available in public databases. Two transcriptome datasets were downloaded from the Gene Expression Omnibus database and analyzed as whole and as partial sets after removing outliers. Differentially expressed genes (DEGs) upregulated in the dataset of OLP versus healthy epithelium were significantly enriched in epidermal developmen

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16

Puišys, Algirdas, Viktorija Auzbikaviciute, Justina Deikuviene, Eglė Vindašiūtė‐Narbutė, and Dainius Razukevicius. "Full versus split thickness flap to increase soft tissue thickness and keratinization of NO‐keratinized mucosa. A 3‐year split mouth randomized clinical trial." Clinical Oral Implants Research 31, S20 (2020): 33. http://dx.doi.org/10.1111/clr.28_13643.

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17

Dhakshaini, MR, RohitS Menon, AnilKumar Gujjari, and Usha Hegde. "A clinical evaluation on the effect of astringent on keratinization of oral mucosa before and after the insertion of complete denture." Indian Journal of Dental Research 30, no. 3 (2019): 347. http://dx.doi.org/10.4103/ijdr.ijdr_620_17.

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18

Sivesh Sangar, Jayanth Kumar Vadivel, and Visalakshi Ramanathan. "Prevalence of smoking in patients with aphthous stomatitis: A retrospective case-control study." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 1755–60. http://dx.doi.org/10.26452/ijrps.v11ispl3.3508.

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Apthous stomatitis represents one of the most common ulcerations occurring in the oral cavity. This ulcer has an exclusive predilection of affecting the non-keratinized mucosa only. The aim of this study was to assess the prevalence of smoking in patients with apthous stomatitis. Seventy-six patients with recurrent apthous stomatitis attending Saveetha Dental Hospital, Chennai were included in the study. The data gathered was entered into an excel table, and the data analysis was done in SPSS. The data analysis revealed that the mean age of the collected samples of 76 patients was 32.21 years,

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19

Gopal, Deepika, N. Malathi, and B. Thirupathi Reddy. "Efficacy of Oral Exfoliative Cytology in Diabetes Mellitus Patients: A Light Microscopic and Confocal Microscopic Study." Journal of Contemporary Dental Practice 16, no. 3 (2015): 215–21. http://dx.doi.org/10.5005/jp-journals-10024-1664.

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ABSTRACT Aim Diabetes mellitus (DM) has become a global problem. By monitoring the health status of these individuals, diabetic complications can be prevented. We aimed to analyze alterations in the morphology and cytomorphometry of buccal epithelial cells of type 2 DM patients using oral exfoliative cytology technique and determine its importance in public health screening, diagnosis and monitoring of diabetes mellitus. Materials and methods The study was carried out in 100 type 2 DM patients and 30 healthy individuals. Smears were taken from the right buccal mucosa and stained by the Papanic

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20

Kutukova, Svetlana, Natalia P. Beliak, Julia V. Ivaskova, Alexey B. Chuhlovin, Andrey I. Yaremenko, and Tatiana S. Ermakova. "Prevalence of herpes simplex virus I, II, cytomegalovirus, Epstein–Barr virus and human papillomavirus (6, 11, 16 and 18) in normal oral mucosa and OSCC patients in Saint-Petersburg (Russia)." Journal of Clinical Oncology 38, no. 15_suppl (2020): e18539-e18539. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e18539.

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e18539 Background: The objective of our study was to evaluate the prevalence of DNA of HSV I, II, CMV, EBV, HPV6.11, HPV16, HPV18 in normal oral mucosa and oral squamous cell carcinoma (OSCC), and determine this association with long-term treatment outcomes and patient survival. Methods: The study included 116 patients with OSCC (stage I-IVB who received standard treatment) and 50 healthy volunteers, median age 60.0 yrs (95% CI 58.0-64.0). Using real-time PCR (polymerase chain reaction), freshlyfrozen samples of the tumor and normal mucous membranes of the cavity were analyzed. mouths, which,

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21

Miyazono, Shoji, Takahito Otani, Kayoko Ogata, et al. "The reduced susceptibility of mouse keratinocytes to retinoic acid may be involved in the keratinization of oral and esophageal mucosal epithelium." Histochemistry and Cell Biology 153, no. 4 (2020): 225–37. http://dx.doi.org/10.1007/s00418-020-01845-1.

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22

Hara, Hitoshi, Tsuneo Misawa, Eri Ishii, et al. "Differential diagnosis of well-differentiated squamous cell carcinoma from non-neoplastic oral mucosal lesions: New cytopathologic evaluation method dependent on keratinization-related parameters but not nuclear atypism." Diagnostic Cytopathology 45, no. 5 (2017): 406–17. http://dx.doi.org/10.1002/dc.23685.

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23

Komori, Taishi, Mitsuaki Ono, Emilio Satoshi Hara та ін. "Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium". Scientific Reports 8, № 1 (2018). http://dx.doi.org/10.1038/s41598-018-21000-0.

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24

"Final Report on the Safety Assessment of Capsicum Annuum Extract, Capsicum Annuum Fruit Extract, Capsicum Annuum Resin, Capsicum Annuum Fruit Powder, Capsicum Frutescens Fruit, Capsicum Frutescens Fruit Extract, Capsicum Frutescens Resin, and Capsaicin1." International Journal of Toxicology 26, no. 1_suppl (2007): 3–106. http://dx.doi.org/10.1080/10915810601163939.

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Capsicum-derived ingredients function as skin-conditioning agents—miscellaneous, external analgesics, flavoring agents, or fragrance components in cosmetics. These ingredients are used in 19 cosmetic products at concentrations as high as 5%. Cosmetic-grade material may be extracted using hexane, ethanol, or vegetable oil and contain the full range of phytocompounds that are found in the Capsicum annuum or Capsicum frutescens plant (aka red chiles), including Capsaicin. Aflatoxin and N -nitroso compounds ( N -nitroso dimethylamine and N -nitrosopyrrolidine) have been detected as contaminants. T

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