Academic literature on the topic 'Oral pathology'

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Journal articles on the topic "Oral pathology"

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Jones, A. V. "Oral pathology." British Dental Journal 199, no. 2 (July 2005): 120. http://dx.doi.org/10.1038/sj.bdj.4812602.

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Renshaw, Andrew. "Oral Pathology." Advances In Anatomic Pathology 20, no. 5 (September 2013): 365. http://dx.doi.org/10.1097/pap.0b013e3182a28a0f.

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Niemiec, Brook A. "Oral Pathology." Topics in Companion Animal Medicine 23, no. 2 (May 2008): 59–71. http://dx.doi.org/10.1053/j.tcam.2008.02.002.

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Radden, B. G. "Oral Pathology." Pathology 19, no. 2 (1987): 210–11. http://dx.doi.org/10.1016/s0031-3025(16)36786-1.

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Hume, W. J. "Oral pathology." Journal of Dentistry 14, no. 6 (December 1986): 272. http://dx.doi.org/10.1016/0300-5712(86)90048-5.

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Smith, C. J. "Oral pathology." Journal of Dentistry 18, no. 6 (December 1990): 354–55. http://dx.doi.org/10.1016/0300-5712(90)90140-a.

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Browne, R. M. "Oral pathology." British Journal of Oral and Maxillofacial Surgery 24, no. 5 (October 1986): 387–88. http://dx.doi.org/10.1016/0266-4356(86)90027-6.

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Browne, R. M. "Oral pathology." British Journal of Oral and Maxillofacial Surgery 28, no. 1 (February 1990): 68–69. http://dx.doi.org/10.1016/0266-4356(90)90024-f.

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Currie, R. "Oral pathology." British Journal of Oral and Maxillofacial Surgery 32, no. 4 (August 1994): 265–66. http://dx.doi.org/10.1016/0266-4356(94)90222-4.

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Miller, N. "Oral pathology: clinical pathologic correlations, 6th edition." British Dental Journal 212, no. 11 (June 2012): 567. http://dx.doi.org/10.1038/sj.bdj.2012.516.

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Dissertations / Theses on the topic "Oral pathology"

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Belfield, Louise Alicia. "Interactions between porphyromonas gingivalis and macrophages in oral pathology." Thesis, University of Plymouth, 2013. http://hdl.handle.net/10026.1/1611.

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Macrophages play a fundamental role in driving both inflammatory and immunosuppressive conditions of the oral mucosa. Periodontitis, a chronic inflammatory condition affecting the supporting structures of the teeth, is widely prevalent, affecting a large proportion of the global population, and has been linked to the development of systemic inflammatory diseases. Oral squamous cell carcinoma (OSCC) is placed sixth in the WHO rankings of cancer incidence worldwide, and despite continuing research into underlying mechanisms, incidence is on the rise. Aberrant macrophage function has been implicated in the pathogenesis of both diseases. On recruitment to sites of inflammation, macrophages become polarised within a spectrum of effector phenotypes depending on the factors they encounter in their microenvironment. These cells are highly plastic and continuously adapt their effector functions in response to locally derived stimuli. Mechanisms have been developed by pathogenic bacteria and transformed host tissues to exploit this plasticity and manipulate macrophage phenotype to facilitate disease progression. However, this plasticity is also available for therapeutic manipulation. The main objectives of this study therefore were to investigate the interactions between macrophages and pathogenic stimuli in the context of oral pathology with a view to identifying novel therapeutic targets. Firstly, a reproducible model of M1 and M2 macrophage polarisation using the THP-1 cell line was established to study their interactions with pathogenic stimuli. Treating the cells with combinations of PMA plus IFNγ or IL-4 for 24 hours led to two distinct populations of cells: PMA + IFNγ treated cells expressed higher levels of pro-inflammatory cytokines TNFα, IL-1β and IL-6, but lower levels of IL-10 and TGF-β, characteristic of M1 macrophages. PMA + IL-4 treated cells expressed lower levels of TNFα, IL-1β and IL-6 and higher levels of IL-10 and TGF-β, characteristic of M2 macrophages. As P. gingivalis LPS is present in the developing periodontal lesion, cytokine expression from macrophages exposed to LPS during polarisation was investigated. Exposure of macrophages to 1 μg/ml Pg LPS during polarisation led to a statistically significant down-regulation of inflammatory cytokines TNFα (10-, 4- and 5.5 –fold decrease in PMA, M1 and M2 cells, respectively) and IL-1β (1.9-, 2.0- and 1.5 –fold decrease in PMA, M1 and M2 macrophages, respectively) in response to subsequent stimulation with LPS. IL-6 production was not affected. The same pattern of cytokine down regulation was observed regardless of LPS species used, and in most cases, at a lower dose of 1 ng/ml LPS during polarisation. Finally, as macrophages recruited to the tumour environment will be influenced by tumour-secreted factors, the response of macrophages to LPS stimulation in the presence of OSCC conditioned media was examined. Contrariwise to polarisation with LPS, exposure of macrophages to OSCC produced factors during polarisation led to an amplification of IL-1β (13.8-, 2.3- and 8.8 –fold increase in PMA, M1 and M2 cells, respectively), and IL-6 (16.8-, 17.3- and 44.9 –fold increase in PMA, M1 and M2 cells, respectively), but not TNFα in response to LPS. Counter intuitively, these findings suggest that LPS manipulation of macrophage polarisation might result in a more M2 –like population of cells, whereas OSCC produced factors may result in a more M1- like population of cells. Viewed therapeutically, one short, single exposure of macrophages to LPS would up-regulate pro-inflammatory cytokines, whereas prolonged or chronic exposure would lead to the down-regulation of pro-inflammatory cytokines, therefore, LPS as a therapeutic modulator of macrophage function in an immunosuppressive (M2) environment to an inflammatory environment (M1) would only be viable as a single dose. For chronic inflammatory disease however, a repasted or prolonged exposure of macrophages to LPS skews macrophages to display a more M2-like cytokine profile and could dampen down detrimental pro-inflammatory cytokine production. The continued study of macrophage/ P. gingivalis interactions may shed light on pathogenic mechanisms not only in oral pathological conditions, but in a range of diseases.
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Wolff, Ewan Douglas Stephens. "Oral pathology of the Archosauria bony abnormalities and phylogenetic inference /." Diss., Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/wolff/WolffE0507.pdf.

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Riffel, Amy Marie. "Osteoblasts aggregates cultivated in a 3-dimensional culture environment rigorously respond to Porphyromonas gingivalis culture supernatants." Thesis, University of Iowa, 2011. https://ir.uiowa.edu/etd/1067.

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An exciting alternative to the current methods for bone regeneration is osseous tissue engineering. One such method focuses on enhancement of osteoblast differentiation through rotary cell culture techniques. The response of osteoblast aggregates to periodontal microorganisms and their by-products will ultimately be important in their success as a method of bone regeneration. In this study, I hypothesize that human embryonic palatal mesenchymal (HEPM, ATCC 1486) pre-osteoblast cells produce different cytokine responses depending upon whether they are grown in a 2-dimensional tissue culture flask or a 3-dimensional tissue culture vessel and whether they are exposed to an un-inoculated, sterile Porphyromonas gingivalis growth medium or exposed to a 24 hour, sterile, P. gingivalis culture supernatant. Objectives: My objectives were first to determine and compare the cytokine response of HEPM, ATCC 1486 pre-osteoblast cells depending upon whether they are grown in a 2-dimensional tissue culture flask or a 3-dimensional tissue culture vessel and whether they are exposed to an un-inoculated, sterile P. gingivalis growth medium or exposed to a 24 hour, sterile, P. gingivalis culture supernatant. Methods: In 3 experiments, 5 X 106 HEPM, ATCC 1486 cells were grown in a 2-dimensional tissue culture flask or a 3-dimensional tissue culture vessel and exposed to an un-inoculated, sterile P. gingivalis growth medium or exposed to a 24 hour, sterile, P. gingivalis culture supernatant and incubated for 72 hours in 5% CO2 at 37oC. Media was removed from the tissue culture flasks or rotary vessels at 0, 1, 2, 4, 8, 12, 24, 36, 48, 60, and 72 hours to determine cytokine concentrations in the Luminex 100 IS Instrument (Luminex®, Austin, TX). HEPM, ATCC 1486 pre-osteoblast cell morphology was assessed by light and scanning electron microscopy at 96 hours. Results: In experiment 1, there were increases in IL-6 and IL-8. The IL-6 response of cells grown in a 2-dimensional tissue culture flask was higher than that of cells grown in a 3-dimensional tissue culture vessel. The IL-8 responses of the cells grown in 2-dimensional, 3-dimensional tissue culture were nearly identical. In light and scanning electron microscopy cells appeared normal and HEPM, ATCC 1486 pre-osteoblast cell aggregates were similar to that previously reported. In experiment 2, there were also increases in IL-6 and IL-8. The IL-6 and IL-8 responses of HEPM, ATCC 1486 pre-osteoblast cells grown in a 3-dimensional tissue culture vessel exposed to a 24-hour, sterile, P. gingivalis culture supernatant were higher than cells exposed to un-inoculated, sterile P. gingivalis growth media. In experiment 3, HEPM, ATCC 1486 pre-osteoblast cells grown in 2-dimensional tissue culture flasks and 3-dimensional tissue culture vessel exposed to a 24 hour, sterile, P. gingivalis culture supernatant produced high levels of IL-6, IL-8, and VEGF. Again, in light and scanning electron microscopy, cells appeared normal. Conclusion: HEPM, ATCC 1486 pre-osteoblast cells display different cytokine profiles depending upon the type of vessel they are cultured in. They also rigorously respond to P. gingivalis culture supernatants suggesting that they may respond to the presence of microorganisms commonly found in the oral cavity and play an active role in immunity during their integration following bone regeneration.
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Chu, Rene. "Age and Sex-Related Differences in Dental Pulp Stem Cells." Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/4830.

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Objective: An in vitro study to determine the age and gender related changes of dental pulp stem cells in regards to proliferative capacity and lineage dependent effects on differentiation capabilities. Material and Methods: Specimens have been collected from a population ranging from 16 yrs of age to 78 yrs of age. Intact, non-carious teeth were collected from the oral surgery department at College of Dentistry at the University of Iowa. A total of 20 specimens were collected. Teeth were collected, sectioned and pulpal tissue collected from the specimens. The pulpal tissue was cut and stored in phosphate buffered saline. The tissue was then subjected to enzymatic digestion and DPSC isolation. Subsequently cell cultures were grown, percentage of Stro-1+ cells and proliferation rate were measured. The DPSC were subjected to differentiation via osteogenic and adipogenic medium. The cells were assessed for osteogenic and adipogenic characteristics using RT- PCR and also replicative senescence using telomere length ratio measurement. Results: Data suggests that with increasing age, there is a decreased proliferative capacity, decreased osteogenic capacity and shortened telomere length. There is no difference in the adipogenic potential and the percentage of DPSC present. There appears to be no difference in DPSCs in regards to proliferative capacity and differentiation potential with regards to gender. A possible gender related effect was noted in osteogenic potential and telomere length. Conclusion: Increasing age has both a decreased proliferative effect and lineage dependent effects on DPSC differentiation potential. Thus this relationship must be accounted for when developing future regenerative therapies.
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Tengan, Kelsey S. "Prospective, comparative assessment of alveolar ridge preservation using Guidor® Easy-Graft® Classic in atrumatic extraction socket." Thesis, University of Iowa, 2017. https://ir.uiowa.edu/etd/5861.

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Objectives: Tooth extraction initiates a cascade of biological events leading to the reduction of alveolar ridge volume. Alveolar ridge preservation (ARP) is a surgical treatment which aims at minimizing hard and soft tissue changes following tooth extraction. Several techniques and materials have been studied and used clinically in ARP. The selection of the biomaterials used for this technique is determined by several factors, such as features of the extraction site, inherent biomaterial properties and handling preferences by the surgeon, among others. The purpose of this study was to evaluate the efficacy of alveolar ridge preservation via the application of Easy-graft CLASSIC® (Sunstar Americas Inc.), an alloplastic bone substitute with unique handling features, following flapless posterior single tooth extraction compared to a particulate freeze-dried bone allograft (FDBA) covered with a collagen wound dressing, which has been advocated as a predictable treatment modality. The primary outcome in this study was bone volumetric reduction of the alveolar ridge assessed using cone beam computed tomography (CBCT) scans obtained at baseline and 16 weeks after tooth extraction and ARP. Methods: This study is part of a multicenter study in collaboration with the University of Maryland School of Dentistry. Seventeen healthy adults treatment planned for a single tooth implants in the area posterior to the canines, excluding third molars, were recruited on the basis of an eligibility criteria. Patients were randomly assigned to the control group or the experimental group. Minimally traumatic extraction of the tooth was completed and the presence of an intact buccal plate of bone was verified. The control group received FDBA and the site was stabilized with a collagen wound dressing and sutures. The experimental group received Easy-graft CLASSIC® with no attempt to approximate the marginal mucosa. Healing was assessed after 1, 2, 4, 8, and 16 weeks. DICOM data was used to assess the alveolar ridge volume and linear changes from baseline to 16 weeks after ARP. Clinical measurements of the buccal gingival thickness, buccal alveolar bone thickness, keratinized gingiva, and socket dimensions were made at the time of the extraction and were subsequently analyzed for possible influences on the observed volumetric and linear outcomes. Results: The mean alveolar ridge volume reduction from baseline to 16 weeks post operatively for the control and the experimental group was 114.96 mm3 and 94.87 mm3, respectively. These values correspond to a reduction of 9.59% for the control group and 13.04% for the experimental group. This difference did not reach statistical significance. The average loss of ridge width was 1.10mm for the FDBA and 1.24mm for the Easy-graft CLASSIC® with no statically significant differences between the two groups. The average loss of buccal bone height and lingual bone height in the FDBA group was 1.12mm and 0.63mm, respectively. Similarly, the average loss of buccal bone height and lingual bone height in the Easy-graft CLASSIC® was 1.19mm and 0.67mm, respectively. There was a weak to moderate positive correlation between buccal tissue thickness and the thickness of the buccal bone and a weak negative correlation between buccal bone thickness and alveolar ridge width reduction. Conclusions: Within the limitations of this study, both treatment groups appear to be effective in alveolar ridge preservation and are associated with similar volumetric and linear bone reduction patterns.
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Poulsen, Christopher. "Differential cytotoxicity of long-chain bases for human oral keratinocytes, fibroblasts, dendritic and oral squamous cell carcinoma cell lines." Thesis, University of Iowa, 2014. https://ir.uiowa.edu/etd/4723.

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Long-chain bases (sphingosine, dihydrosphingosine, and phytosphingosine) are present in the oral cavity and have potent antimicrobial activity against oral pathogens. However, little is known about their cytotoxicity for oral cells, an important step in considering their potential as future antimicrobial agents for oral infections. In this study, primary oral keratinocytes, primary oral fibroblasts, dendritic cells, and oral squamous cell carcinoma cells were exposed to 10.0-640.0 µM long-chain bases and glycerol monolaurate (GML) in cell culture medium containing resazurin (e.g., Alamar Blue, Invitrogen Corp., Carlsbad, CA). Cell metabolism was assessed at 48 hours by the reduction of resazurin to resorufin. Percent cytotoxicity was defined as the median fluorescence intensity (MFI) of resazurin in cell culture media of cells treated with dilutions of long-chain bases/MFI of resazurin in cell culture media of untreated cells x 100, and the lethal dose 50 (LD50) was determined from the dose response curve where the 50 percent cytotoxicity intercepts with the long-chain base concentration on the x-axis. For all cells, the LD50 (mean µM + std err) of sphingosine, dihydrosphingosine, phytosphingosine, and GML were 69.7 (1.7), 29.2 (1.7), 20.6 (1.7), and 134.3 (1.7), respectively. Primary oral keratinocytes were more resistant to long chain bases, whereas oral fibroblasts, dendritic cells, and oral squamous cell carcinoma cells were more susceptible. Overall, long chain bases have LD50 for oral keratinocytes, oral fibroblasts, dendritic cells, and oral squamous cell carcinoma cells that are considerably higher than the minimal inhibitory concentrations for oral pathogens, a finding important to their future potential as therapeutics for prevention or treatment of periodontal disease infections.
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Rinehart, Sarah. "Periodontal phenotype and supracrestal soft tissue dimensions – clinical correlations and their impact on post-extraction volumetric changes." Thesis, University of Iowa, 2017. https://ir.uiowa.edu/etd/5834.

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Objectives: Extraction of a tooth leads to a series of healing events that are intimately associated with dimensional changes in the alveolar ridge that typically result in a net volume loss. Previous studies have evaluated the extent and pattern of those resorptive changes, however it remains challenging to predict the degree of change that will occur, as numerous local and systemic factors may play a role in the biologic events that follow tooth extraction. The purpose of this study was to assess the role that phenotypic characteristics of the periodontium play in the alveolar ridge remodeling processes that take place following single tooth extraction. Methods: Healthy patients in need of a single tooth extraction in the maxillary arch from second premolar to second premolar (inclusive) and who met a predefined eligibility criteria were enrolled in this study. An impression of the maxillary arch was made and a cone beam computed tomography (CBCT) scan of the maxilla was obtained immediately prior to tooth extraction at the baseline visit. At the time of the extraction, clinical measurements were made including probing depth, bone sounding, buccal keratinized mucosa width, buccal and palatal alveolar bone thickness, and buccal and palatal soft tissue thickness. Fourteen weeks following the baseline intervention, patients returned to the clinic for a second impression of the maxillary arch and a second CBCT of the maxilla. Linear and volumetric bone measurements were made using the data obtained from the CBCT scans. The casts obtained from the impressions were digitally scanned and volumetric measurements were made from the digitized data to assess volume changes of the residual ridge. The primary outcome of interest was the volumetric percent reduction of the alveolar ridge following single tooth extraction. Spearman correlations were utilized to evaluate relationships between variables and modeling was completed to predict the percentage of volumetric change in the hard and soft tissues using the clinical variables. Results: A total of 21 patients participated in the study, 19 patients are included in this analysis (one patient has yet to complete the study, one patient was later excluded due to lack of compliance). Of the 19 extraction sites included, 17 were maxillary premolar teeth. At baseline, the average buccal plate thickness was 1.09 mm. After 14 weeks, the average loss of alveolar bone width was 1.66 mm. The average loss of buccal bone height was 1.10 mm and mean loss of palatal bone height was 1.36 mm. The average percentage volumetric reduction of the bone as measured from a CBCT scan was 26.42% after 14 weeks of healing. Mean percentage volumetric reduction of the ridge, as measured from a digitized cast, was 18.89%. There was no statistically significant correlation noted between the bone and ridge volumetric measurements. While there were no statistically significant correlations noted between the thickness of the buccal bone and the amount of volumetric remodeling, statistically significant negative correlations were found between the buccal bone thickness and the loss of alveolar bone width (rs = -0.66418, p-value = 0.0019). In addition, a statistically significant correlation was noted between the reduction in alveolar bone width and the loss of buccal ridge height (rs = 0.55707, p-value = 0.0132). Modeling methods found that increased thickness of the buccal soft tissue was predictive of increased percentage volumetric reduction of hard tissues (coeff = 37.24, p-value = 0.0301). Conclusions: Increased buccal soft tissue thickness was found to be predictive of increased percent volumetric reduction of alveolar bone. Thinner buccal bone was correlated with increased loss of alveolar bone width. While statistically significant correlations were identified, further studies with larger sample size are needed to better understand these relationships.
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García, Loera José Miguel. "Patient satisfaction and oral health-related quality of life outcomes in edentulous patients being treated with complete dentures by dental students at the University of Iowa College of Dentistry and Dental Clinics." Thesis, University of Iowa, 2018. https://ir.uiowa.edu/etd/6421.

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Objectives: The aim of this study is to investigate the impact of multiple factors in the Oral Health Related Quality of Life of patients being treated with Conventional Complete Dentures, including: a) Level of expertise of the dental provider (third year dental student vs. fourth year dental student); b) Length of time edentulous; c) Number of previous prostheses; d) Race; e) Sex; f) Age; g) Systemic conditions; h) Condition of the bone ridge; i) Economic factor and insurance coverage, in patients at the University of Iowa College of Dentistry (D3 and D4 Clinics). Materials and methods: Eighty-one subjects who had been completely edentulous (49 men and 32 women; age range from 23 to 93 years old, mean of 58.9+13) for a minimum of 3 months were recruited. Out of the eighty-one, eleven subjects were not included in the final analysis because their prostheses were not delivered due to various reasons (time, death, discontinued treatment). Subjects were asked to complete the OHIP-EDENT (Oral Health Impact Profile for Edentulous Patients) and the patient satisfaction questionnaire to record data at baseline, at 1-week post-delivery and at 1-month post-delivery of the new prostheses. Additional to these two instruments, the PDI Classification instrument (to assess bone/tissue condition) and the Kapur Index (to assess retention/stability of the new prostheses) were also used. Baseline comparisons of subjects seen at the D3 vs. the D4 clinic were carried out using chi-square tests of association for nominal ordinal variables, and the Wilcoxon-Mann-Whitney test for ordinal and quantitative outcomes. Bivariate analyses were conducted to assess potential relationships between covariates and the primary outcomes (total OHIP-EDENT and total Patient Satisfaction Questionnaire scores at one-week and one-month follow-ups). The Spearman rank correlation was used to identify increasing or decreasing relationships between primary outcomes and quantitative and ordinal variables; the Wilcoxon-Mann-Whitney test was used to assess relationships between primary outcomes and categorical covariates. Results: Overall, there was not enough statistical evidence to conclude that patient satisfaction and quality of life were significantly affected by most of the factors being studied. However, there was suggestive evidence of the presence of higher level of quality of life for patients seen in the D4 clinic (students with higher level of expertise). At the one-month follow-up, the comparison of the total OHIP-EDENT score between the D3 and D4 clinics was significant at the 0.05 level (p=0.018, exact Wilcoxon-Mann-Whitney test). The total OHIP-EDENT scores tended to be lower (indicating greater satisfaction) in the subjects seen in the D4 clinic. Two of the nineteen items from the patient satisfaction questionnaires also suggested a greater level of patient satisfaction for patients seen in the D4 clinic (students with higher level of expertise). Conclusion: 1) Oral health related quality of life at 1-week follow-up was not significantly different between patients treated by D3 and D4 students. 2) Oral health related quality of life at 1-week follow up was significantly better for patients who had been edentulous for a longer period of time than those who were recently edentulous. However, this result can only be considered suggestive due to the need for adjustment for multiple comparisons. 3) Oral health related quality of life at 1-month follow up was significantly better for patients treated by D4 students in comparison to D3 students. However, this result can only be considered suggestive due to the need for adjustment for multiple comparisons. 4) Overall, patient satisfaction at 1-week follow-up was not significantly different between patients treated by D3 and D4 students. However, patients treated in the D4 clinic reported significantly better outcomes in regard to speaking with their new prostheses. 5) Overall, patient satisfaction at 1-month follow-up was not significantly different between patients treated by D3 and D4 students. However, patients treated in the D4 clinic reported that they could chew better with their new prostheses compared to those treated by D3 students.
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Handoo, Nidhi Q. "Analysis of bone activity of jaws using scintigraphy on patients before, during and after treatment with IV bisphosphonates: a retrospective study." Thesis, University of Iowa, 2009. https://ir.uiowa.edu/etd/240.

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Bisphosphonates are non-metabolized compounds with high affinity for bone mineral hydroxyapatite. These compounds are used in diagnosis and treatment of malignancies metastatic to bone. Currently, IV bisphosphonates are used to treat hypercalcemia of malignancy. There are also "off label" uses to prevent, minimize, or delay skeletal morbidity associated with metastatic bone disease. Osteonecrosis of the jaws is an intraoral complication that has been reported after administration of intravenous nitrogen-containing bisphosphonates. Bisphosphonate associated osteonecrosis (BON) may remain asymptomatic for many weeks or months and is usually recognized clinically by the identification of exposed bone in the oral cavity. Other clinical features of BON are pain, ulceration, necrotic bone and/or local inflammation of the mucosa. Though these are generally all of which are seen later in the disease process. It is theorized that nuclear medicine imaging may play a crucial role in the recognition and identification of these bone lesions earlier in the disease process. Due to the high bone affinity, bisphosphonates coupled to a gamma-emitting radioisotope have been used as bone-scanning agents. Technetium is most commonly used gamma-emitting radioisotope in conjunction with a bisphosphonate. In University of Iowa Hospitals and Clinics, the material of choice is technetium99 methylene diophosphonate (Tc99 MDP). Bisphosphonates have a long half-life in bone and long-term treatment with non-tagged therapeutic bisphosphonates may saturate bone adherence sites and interfering with a single-dose scanning agent used for bone scintigraphy. Alternatively, therapeutic bisphosphonates may alter bone physiology such that scintigraphic findings could be enhanced in some locations and decreased in others. Limitations of the use of scintigraphy in patients on bisphosphonate therapy include low resolution and a difficulty in differentiating between inflammation and metastatic disease especially during the latter stages of the disease. In an effort to understand the effects of this compound on scintigraphic imaging, this study will evaluate any potential changes during and after use of IV bisphosphonates that may confound imaging.
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Anadioti, Evanthia. "Internal and marginal fit Of pressed and cad lithium disilicate crowns made from digital and conventional impressions." Thesis, University of Iowa, 2013. https://ir.uiowa.edu/etd/2435.

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Objectives: The aim of the study was to evaluate in vitro the 3D and 2D marginal fit and 2D internal fit of CAD and Press all-ceramic crowns made from digital and conventional impressions. Methods: A dentoform replica tooth (#30) was prepared for an all-ceramic crown (Master Die). 30 impressions were made with PVS material; 30 definitive casts were poured in type IV gypsum. 30 LavaTM C.O.S. impressions were made; 30 resin models were produced. 30 crowns were waxed and pressed in lithium disilicate (IPS e.max Press) (15 from each impression technique) and 30 crowns were milled from lithium disilicate blocks (IPS e.max CAD) (15 from each impression technique) utilizing the E4D scanner and milling engine. The Master Die and the intaglio of the 60 crowns were digitized using a 3D laser coordinate measurement machine (CMM). For each specimen a separate data set was created for the Qualify 2012 software. The two data sets, digital master die and digital intaglio of the crown, were merged using Best-Fit alignment. An area above the cavosurface margin with 0.75mm occlusal-gingival width circumferentially was defined. The 3D marginal fit of each specimen was an average of all 3D measurement values on that specified area for all the crowns, and it was used for the statistical analysis. For the 2D measurements, two sections, one facial-lingual and one mesial-distal, were made through the grooves on the standardized metal base of the tooth. The distance between the die and the intaglio surface of the crown were measured at 7 standardize points (2 on the margins, 2 at 0.75mm above the margin, 2 on the axial walls and 1 on the occlusal surface). For the 3D measurements one-way ANOVA with post-hoc Tukey's HSD test was used to determine whether there were significant differences in mean marginal fit values among four experimental groups (alpha=0.05). For the 2D data, a two-way ANOVA was performed to detect a significant interaction between the type of impressions and the type of crowns on the marginal and internal fit (alpha=0.05). Results: One-way ANOVA revealed that the 3D mean marginal fit for Group A (0.048mm±SD 0.009) was significantly lower than those obtained from other three experimental groups Group B (0.088mm±SD 0.024), Group C (0.089mm±SD 0.020) and Group D (0.084mm±SD 0.021), while no significant differences were found among Group B, C and D. Similar results were found regarding the 2D marginal fit Group A (0.040mm±SD 0.008), Group B (0.076mm±SD 0.0234), Group C (0.075mm±SD 0.0148) and Group D (0.073mm±SD 0.0258). For the 2D internal fit, Group C (0.2109mm±SD 0.0410) had statistically significant poorer internal fit than the other three groups Group A (0.1105mm±SD 0.0474), Group B (0.1158±SD 0.02) and Group D (0.1454MM±SD 0.0245), while no significant difference was found among those three groups. Conclusions: The combination of PVS impression method and Press fabrication technique produced the most accurate 3D and 2D marginal adaptation. The combination of LavaTM C.O.S. impression and Press fabrication technique produced the poorer 2D internal fit.
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Books on the topic "Oral pathology"

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Seifert, Gerhard, ed. Oral Pathology. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80169-3.

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C, Southam J., ed. Oral pathology. Oxford: Oxford University Press, 1985.

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Cawson, R. A. Oral pathology. 2nd ed. Edinburgh: Churchill Livingstone, 1999.

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Cawson, R. A. Oral pathology. Edinburgh: Churchill Livingstone, 1987.

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Reichart, Peter A. Oral pathology. Stuttgart: Thieme, 2000.

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Cawson, R. A. Oral pathology. Edinburgh: Churchill Livingstone, 1993.

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Waal, Isaäc van der. Oral pathology. Chicago: Quintessence Pub. Co., 1988.

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Soames, J. V. Oral pathology. 3rd ed. Oxford: Oxford University Press, 1998.

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C, Southam J., ed. Oral pathology. 4th ed. Oxford: Oxford University Press, 2005.

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C, Southam J., ed. Oral pathology. 2nd ed. Oxford: Oxford University Press, 1993.

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Book chapters on the topic "Oral pathology"

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Ramer, Naomi, Molly Cohen, Trina Sengupta, Chandni Desai, John W. Hellstein, Beomjune B. Kim, Ryan J. Smart, Waleed Zaid, and Prashanth Konatham-Haribabu. "Oral Pathology." In Oral Board Review for Oral and Maxillofacial Surgery, 223–60. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-48880-2_8.

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Ahmed, Abdul, Shahme Farook, and Michael Perry. "Oral Pathology." In Oral and Maxillofacial Surgery, 441–71. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-25473-4_20.

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Hegarty, Anne, and Alison Rich. "Gingival Pathology." In Contemporary Oral Medicine, 1143–73. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-72303-7_15.

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Takata, Takashi, Mutsumi Miyauchi, Ikuko Ogawa, and Alan Mighell. "Odontogenic Pathology." In Contemporary Oral Medicine, 471–554. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-72303-7_22.

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Hegarty, Anne, and Alison Rich. "Gingival Pathology." In Contemporary Oral Medicine, 1–31. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-28100-1_15-1.

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Takata, Takashi, Mutsumi Miyauchi, Ikuko Ogawa, and Alan Mighell. "Odontogenic Pathology." In Contemporary Oral Medicine, 1–84. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-28100-1_22-1.

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"Pathology." In Oral Medicine, 37–141. Elsevier, 2006. http://dx.doi.org/10.1016/b978-0-443-10037-6.50007-7.

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Woo, Sook-Bin. "Oral Pathology." In Dental Secrets, 43–70. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-323-26278-1.00004-0.

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Gautam, Mohit, and Gaurav Anand. "Oral Pathology." In TARGET MDS: Image Based Questions, 140. Jaypee Brothers Medical Publishers (P) Ltd., 2017. http://dx.doi.org/10.5005/jp/books/13031_10.

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Odell, Edward. "Oral pathology." In Essential Skills for Dentists, 459–68. Oxford University PressOxford, 2006. http://dx.doi.org/10.1093/oso/9780198526193.003.0028.

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Abstract An understanding of oral disease underpins much of dentistry and it is therefore difficult to define the boundaries of the subject of oral pathology. Many competencies founded in pathological knowledge are to be found elsewhere in this book, particularly in sections on oral surgery, oral medicine, cardiology and periodontology. Competencies relating to oral pathology are given in the second edition of the General Dental Council’s (GDC) The First Five Years: a framework for undergraduate dental education(GCD 2002) the Quality Assurance Agency’s benchmark statement for dentistry (QAA 2000, 2002) and the European Union’s Competences Required for the Practice of Dentistry in the European Union (European Union 1998). All three organizations actively promote the concept of interdisciplinary teaching and integrated courses. As a result competencies in oral pathology may be partly subsumed into problem-based learning, in courses including general pathology, medicine and surgery or in integrated courses in oral medicine, microbiology, pathology, surgery, radiology and therapeutics.
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Conference papers on the topic "Oral pathology"

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Bashir, Raja Muhammad Saad, Hanya Mahmood, Muhammad Shaban, Shan E. Ahmed Raza, Muhammad Moazam Fraz, Syed Ali Khurram, and Nasir Rajpoot. "Automated grade classification of oral epithelial dysplasia using morphometric analysis of histology images." In Digital Pathology, edited by John E. Tomaszewski and Aaron D. Ward. SPIE, 2020. http://dx.doi.org/10.1117/12.2549705.

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Folmsbee, Jonathan, Margaret Brandwein-Weber, and Scott T. Doyle. "Combining multiple ground truth annotations for segmentation training for oral cavity cancer." In Digital and Computational Pathology, edited by John E. Tomaszewski and Aaron D. Ward. SPIE, 2023. http://dx.doi.org/10.1117/12.2654301.

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Balachandran, Dhadma, Margaret Brandwein-Weber, Jonathan Folmsbee, and Scott Doyle. "Comparing architectural features between heuristically human-annotated and Artificial Intelligence (AI) generated tumor and satellite labels in early-stage oral cavity cancer." In Digital and Computational Pathology, edited by John E. Tomaszewski and Aaron D. Ward. SPIE, 2021. http://dx.doi.org/10.1117/12.2581153.

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Naik, Keyur, Malvin N. Janal, Jason Chen, Daniel E. Bandary, Branden Brar, and Aditi Bhattacharya. "Abstract 2041: Lesion pathology and oral-cancer associated pain in the 4NQO oral carcinogenesis model." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-2041.

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Kolevatykh, Ekaterina Petrovna, and Svetlana Vadimovna Potekhina. "Periodontopathogenic microflora of the oral cavity in patients with autoimmune pathology." In International Research Conference on Technology, Science, Engineering & Management. Seattle: Professional science, 2021. http://dx.doi.org/10.54092/9781794752917_66.

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Ram, Dharma. "Oral Abstract." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685335.

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Introduction: Uterine sarcoma accounts for nearly 3% of all uterine malignancies. They have 4 major pathology includes endometrial stromal sarcoma high grade, ESS low grade, uterine leiomyosarcoma (uLMS) and undifferentiated uterine sarcoma (UUS). Recent WHO classification 2014, recognizes low grade ESS and high grade ESS as distinct entity. They differ from endometrial carcinoma in their aggressive nature and poor prognosis. We review our database and found total 44 eligible patient treated at our institute. Materials and Methods: Its retrospective analysis of computer based database of our institute from January 2009 to December 2015. We analyzed demographic, pathological, treatment and survival data. Results: Total 44 patient treated for uterine sarcoma at our institute. Among these 16 were operated at our institute during study period. Here we reporting results of operated patients at our institute. The histological diagnosis LMS (5/16), ESS-L (4/16), MMMT (3/16), UUS (3/16) and ESS-H (1/16). Stage distribution was stage I, (6/16) stage II, (5/16) stage III, (3/16) stage IV, (0/16) and unknown stage (2/16). Two patients underwent completion surgery for outside myomectomy. The adjuvant treatment was CT in 3/16, CT with RT in 7/16, HT in 4/16 and one lost to follow up with one was put on observation. Median follow up is 30 month with 14 patients alive and one lost to follow up. At last follow up 4 patients alive with metastatic disease and 10 patients alive with no evidence of disease. Conclusion: Uterine sarcoma are uncommon disease with
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Banu, M. Sheerin, and Krishnan Nallaperumal. "A novel color feature extraction technique for retrieval of oral pathology images." In 2010 IEEE International Conference on Computational Intelligence and Computing Research (ICCIC). IEEE, 2010. http://dx.doi.org/10.1109/iccic.2010.5705796.

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Delfino, I., C. Camerlingo, F. Zenone, G. Perna, V. Capozzi, N. Cirillo, G. M. Gaeta, and M. Lepore. "Micro-Raman spectroscopy of tissue samples for oral pathology follow-up monitoring." In SPIE Photonics Europe, edited by Jürgen Popp, Wolfgang Drexler, Valery V. Tuchin, and Dennis L. Matthews. SPIE, 2010. http://dx.doi.org/10.1117/12.852803.

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Chuenjitwongsa, Supachai, Krerk Piromsopa, and Risa Chaisuparat. "The Satisfaction of Using an Oral Pathology Mobile Application (PathoPal) in Dental Students." In TENCON 2023 - 2023 IEEE Region 10 Conference (TENCON). IEEE, 2023. http://dx.doi.org/10.1109/tencon58879.2023.10322526.

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"5th National and 1st International Symposium of Italian Society of Oral Pathology and Medicine." In 5th National and 1st International Symposium of Italian Society of Oral Pathology and Medicine. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88945-672-7.

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