Log in

Relevant bibliographies by topics / Orally disintegrating tablet / Journal articles

To see the other types of publications on this topic, follow the link: Orally disintegrating tablet.

Journal articles on the topic 'Orally disintegrating tablet'

Author: Grafiati

Published: 10 September 2021

Last updated: 29 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Orally disintegrating tablet.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Chue, Pierre, Barry Jones, Cindy C. Taylor, and Ruth Dickson. "Dissolution Profile, Tolerability, and Acceptability of the Orally Disintegrating Olanzapine Tablet in Patients with Schizophrenia." Canadian Journal of Psychiatry 47, no. 8 (2002): 771–74. http://dx.doi.org/10.1177/070674370204700809.

Full text

Abstract:

Objectives: This pilot study investigates the dissolution profile, tolerability, and acceptability of an orally disintegrating olanzapine tablet in patients with schizophrenia. Method: Eleven patients with schizophrenia stabilized on oral olanzapine (mean dosage 12.7 mg daily [SD5.2]) were given an orally disintegrating olanzapine tablet, rather than their usual tablet, daily for 7 days. At each visit, visual assessments were made for elapsed time to initial disintegration (every 15 seconds) and complete disintegration (every 1 minute). At the end of the study, patients completed a drug-accept

APA, Harvard, Vancouver, ISO, and other styles

2

Draksiene, Gailute, Brigita Venclovaite, Lauryna Pudziuvelyte, Liudas Ivanauskas, Mindaugas Marksa, and Jurga Bernatoniene. "Natural Polymer Chitosan as Super Disintegrant in Fast Orally Disintegrating Meloxicam Tablets: Formulation and Evaluation." Pharmaceutics 13, no. 6 (2021): 879. http://dx.doi.org/10.3390/pharmaceutics13060879.

Full text

Abstract:

The aim of the present investigation was to formulate fast disintegrating tablets of meloxicam by wet granulation technique using medium molecular weight chitosan. The orally disintegrating tablets of meloxicam with chitosan showed good mechanical and disintegration properties and good dissolution rate when prepared in tablet press using 10.8 kN and 11.0 kN compression force. Chitosan is a suitable biopolymer to moderate the disintegration process in orally disintegrating tablets.

APA, Harvard, Vancouver, ISO, and other styles

3

Eremin, V. A., E. V. Blynskaya, and V. V. Bueva. "Orally disintegrating tablets: mechanisms, preparation methods, problems and achievements." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 6 (December 19, 2023): 25–32. http://dx.doi.org/10.33920/med-13-2306-03.

Full text

Abstract:

The oral route of drug administration is considered one of the preferred delivery methods. In recent years, orally disintegrating tablets (ODTs) have become convenient pharmaceutical dosage forms, especially for specific patient populations such as pediatric, geriatric, and psychiatric patients with dysphagia. Rapid disintegration and increased bioavailability are some of the essential characteristics of ODTs that make them superior to other traditional pharmaceutical dosage forms. Orally disintegrating tablets are pills that disintegrate within a few seconds after being placed in the oral cav

APA, Harvard, Vancouver, ISO, and other styles

4

Shashank Khailkhura, Bhavana Singh, Deepika Joshi, and Nidhi Semwal. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0124.

Full text

Abstract:

Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

APA, Harvard, Vancouver, ISO, and other styles

5

Shashank, Khailkhura, Singh Bhavana, Joshi Deepika, and Semwal Nidhi. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. https://doi.org/10.5281/zenodo.7180875.

Full text

Abstract:

Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

APA, Harvard, Vancouver, ISO, and other styles

6

Nestorovska-Gjosevska, Biljana Nestorovska-Gjosevska, Marija Glavas-Dodov, and Katerina Goracinova. "Orally disintegrating tablet: formulation design and optimisation using Response Surface Methodology." Macedonian Pharmaceutical Bulletin 51 (2005): 15–22. http://dx.doi.org/10.33320/maced.pharm.bull.2005.51.003.

Full text

Abstract:

The objective of this study was to develop diazepam orally disintegrating tablets and to optimize tablets characteristics using response surface methodology (RSM). Tablets were prepared by direct compression of mixture containing mannitol, copovidone, crosspovidone flavor and lubricant. A full factorial design for 2 factors at 3 levels each was applied to investigate the influence of 2 formulation variables on the mechanical strength/hardness, the percent of friability, disintegration time and dissolution of the poorly soluble active ingredient. The amounts of copovidone and crosspovidone were

APA, Harvard, Vancouver, ISO, and other styles

7

Alami-Milani, Mitra, Sara Salatin, Elaheh Nasiri, and Mitra Jelvehgari. "Preparation and optimization of fast disintegrating tablets of isosorbide dinitrate using lyophilization method for oral drug delivery." Therapeutic Delivery 12, no. 7 (2021): 523–38. http://dx.doi.org/10.4155/tde-2020-0127.

Full text

Abstract:

Background: Orally disintegrating tablets rapidly disintegrate in saliva and then swallowed without the need for water. Materials & methods: The orally disintegrating tablets were prepared by freeze-drying of an aqueous dispersion of isosorbide dinitrate containing a matrix former (gelatin), a cryoprotectant (mannitol), a plasticizer (glycerin) and a dissolution enhancer (Tween/polyethylene glycol). Results: Results demonstrated that the selected formulation, Ft9, disintegrated within 1 min and showed faster dissolution rate compared with the commercial tablet. Conclusion: Having a fast di

APA, Harvard, Vancouver, ISO, and other styles

8

Dowson, AJ, EA MacGregor, RA Purdy, WJ Becker, J. Green, and SL Levy. "Zolmitriptan Orally Disintegrating Tablet is Effective in the Acute Treatment of Migraine." Cephalalgia 22, no. 2 (2002): 101–6. http://dx.doi.org/10.1046/j.1468-2982.2002.00319.x.

Full text

Abstract:

A new formulation of zolmitriptan has been developed that dissolves on the tongue without the need for additional fluid intake. In this double-blind, parallel study, 471 patients were randomized to receive the zolmitriptan orally disintegrating tablet 2.5 mg( n=231) or matching placebo ( n=240) to treat a single moderate or severe migraine. Headache relief following zolmitriptan 2.5 mg (63%) was significantly greater than with placebo (22%) at 2 h post-dose (primary endpoint; P < 0.0001). The zolmitriptan orally disintegrating tablet was also significantly more effective than placebo for 1-

APA, Harvard, Vancouver, ISO, and other styles

9

Kumar Bhasin, Rakesh, Nirika Bhasin, and Pradip Kumar Ghosh. "Advances in Formulation of Orally Disintegrating Dosage Forms: A Review Article." Indo Global Journal of Pharmaceutical Sciences 01, no. 04 (2011): 328–53. http://dx.doi.org/10.35652/igjps.2011.33.

Full text

Abstract:

Oral disintegrating tablets are solid dosage form containing medicinal substances which disintegrates rapidly, usually within a matter of seconds, when placed upon the tongue The products are designed to disintegrate or dissolve rapidly on contact with saliva, thus eliminating the need for chewing the tablet, swallowing an intact tablet, or taking the tablet with water. ODT is general form of nomenclature for tablets that disintegrate rapidly or instantly in the oral cavity. Other alias are Quick Dissolve, Rapid Dissolve, Rapid Disintegrating, Fast Disintegrating, Fast Melt, Flash Melt and Mou

APA, Harvard, Vancouver, ISO, and other styles

10

Chono, Sumio, Katsuki Nakamura, and Megumi Matsui. "Physical properties of lansoprazole orally disintegrating tablets." Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector 13, no. 1 (2016): 5–8. http://dx.doi.org/10.1177/1741134316673226.

Full text

Abstract:

Here we examined the physical properties of one branded and five generic lansoprazole orally disintegrating tablets (formulations A and B, C, D, E, and F, respectively), including their hydrophilia and tablet strength and the strength required to push the tablets out of a press through package. The wetting time of formulation F (38 ± 4 s) was approximately 1.5–2.7 fold of that of formulations A, B, C, D, and E (25 ± 2, 14 ± 1, 14 ± 1, 16 ± 1, and 22 ± 1 s, respectively). Formulations B, C, D, E, and F had hardness (>3 kgf) and friability (<1%) that could endure impact and vibration of th

APA, Harvard, Vancouver, ISO, and other styles

11

Teaima, Mahmoud, Sandra Hababeh, Mai Khanfar, Fares Alanazi, Doaa Alshora, and Mohammed El-Nabrawi. "Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet." Pharmaceutics 14, no. 2 (2022): 425. http://dx.doi.org/10.3390/pharmaceutics14020425.

Full text

Abstract:

Pioglitazone Hydrochloride (PGZ) suffers from poor aqueous solubility. The aim of this research was to design orally disintegrating tablets with self-nanoemulsifying properties (T-SNEDDS) to improve the Pioglitazone solubility and dissolution rate. Three liquid self-nanoemulsifying systems (L-SNEDDS) were formulated and evaluated for transmittance percentage, emulsification time, particle size, Poly dispersity index (PDI), percentage of content, solubility and stability. The optimum L-SNEDDS formula was converted to a solidified self-nanoemulsifying drug delivery system (S-SNEDDS) by adsorptio

APA, Harvard, Vancouver, ISO, and other styles

12

Singhal, Peeush. "OPTIMIZED FAST DISINTEGRATING TABLETS, BOOSTED OSELTAMIVIR PHOSPHATE ORALLY FAST DISINTEGRATING TABLETS." Journal of Medical pharmaceutical and allied sciences 10, no. 6 (2021): 3781–88. http://dx.doi.org/10.22270/jmpas.v10i6.1479.

Full text

Abstract:

Background Around 33% of the populace (fundamentally pediatric and geriatric) has gulping hardships, bringing about helpless consistence with oral tablet drug treatment which prompts decreased in general treatment viability. For this explanation, tablets that can quickly break down or deteriorate in the oral cavity have drawn in a lot of consideration. Objective research was designed to develop and evaluate boosted orally fast disintegrating tablets (OFDT) for oro-buccal drug delivery of oseltamivir phosphate. Methods In the present study six formulations of mouth dissolving tablet of oseltami

APA, Harvard, Vancouver, ISO, and other styles

13

Siddheshwar, Suhas Shivaji, Asmita Bhausaheb Ghorpade, Someshwar Dattatraya Mankar, and Santosh Bhausaheb Dighe. "Formulation and Drug Release Study of Rivaroxaban Oral Disintegrating Tablets Using Various Super-Disintegrants." International Journal of Experimental Research and Review 36 (December 30, 2023): 147–55. http://dx.doi.org/10.52756/ijerr.2023.v36.014.

Full text

Abstract:

This study aims to improve Rivaroxaban's solubility, dissolution, and bioavailability. Orally disintegrating tablets (ODTs) made with super-disintegrants like crospovidone, sodium starch glycolate, and cross-carmellose sodium will do this. Tablet preparation used direct compression and formulation optimization with design expert software. After a thorough factorial design and evaluation of pre- and post-compression parameters, the F3 batch, which contained Rivaroxaban (7.97%), Crospovidone (3.59%), Croscarmellose sodium (5.18%), Sodium Starch Glycolate (5.18%), Lactose Anhydrous (31.08%), Mann

APA, Harvard, Vancouver, ISO, and other styles

14

Wu, Tong, Guanhua Wang, Caihong Shi, et al. "Development and evaluation of orally disintegrating tablets containing the mosapride resin complex." Acta Pharmaceutica 68, no. 2 (2018): 159–70. http://dx.doi.org/10.2478/acph-2018-0017.

Full text

Abstract:

Abstract The purpose of this study was to prepare a mosapride citrate-resin (Amberlite® IRP 88) complex and orally fast-disintegrating tablets of the resin complex. The resinate complex of mosapride-Amberlite® IRP 88, mass ratio 2:1, was prepared in an ethanol-water solution. The effects of alcohol concentration, temperature, and pH of the solution on complex formation were evaluated. The complex physicochemical properties were characterized by differential scanning calorimetry, X-ray diffraction and scanning electron microscopy. Orally disintegrating tablets were prepared by direct compressio

APA, Harvard, Vancouver, ISO, and other styles

15

Pullen, Richard L. "Administering an orally disintegrating tablet." Nursing 38, no. 1 (2008): 18. http://dx.doi.org/10.1097/01.nurse.0000305898.88922.df.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Singh, Sudarshan, S. S. Shyale, and P. Karade. "Formulation and Evaluation of Orally Disintegrating Tablets of Lamotrigine." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 2 (2015): 2881–88. http://dx.doi.org/10.37285/ijpsn.2015.8.2.11.

Full text

Abstract:

The aim of this study was to design orally disintegrating tablet (ODT) of Lamotrigine. It is an Antiepileptic drug which is widely used in epilepsy. It is also used in simple and complex partial seizures and secondary generalized tonic-clonic seizures. It is poorly water soluble drug (0.46 mg/ml). Thus, an attempt was made to enhance the water solubility by complexation with β-cyclodextrin (1:1 molar ratios). The orally disintegrating tablet of lamotrigine was prepared by direct compression method using different concentration of superdisintegrants such as Sodium starch glycollate, croscarmell

APA, Harvard, Vancouver, ISO, and other styles

17

Rahane, RD, and Punit R. Rachh. "A REVIEW ON FAST DISSOLVING TABLET." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 50–55. http://dx.doi.org/10.22270/jddt.v8i5.1888.

Full text

Abstract:

The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. The popularity and usefulness of the formulation resulted in development of several FDT technologies. These techniques render the disintegration of tablet rapidly and dissolve in mouth in five seconds without chewing

APA, Harvard, Vancouver, ISO, and other styles

18

Nabila Nabila and Sry Ulina Karo-Karo. "Exploring natural disintegrant as alternative excipients sources for tablet formulation: A systematic review." International Journal of Science and Research Archive 13, no. 2 (2024): 3296–305. https://doi.org/10.30574/ijsra.2024.13.2.2530.

Full text

Abstract:

Optimizing the disintegration and dissolution of orally administered tablets is crucial for releasing active pharmaceutical ingredients (APIs) for absorption. This review explores disintegrant research, focusing on natural super disintegrants and co-processed excipients that collected from 2010-2024. Natural disintegrants such as Silicified Oryza Sativa Starch, Plantago ovata mucilage, and gum karaya show promising results. Silicified Oryza Sativa Starch enhances paracetamol tablet disintegration, while Plantago ovata mucilage outperforms Crosspovidone. Gum karaya offers a cost-effective, bioc

APA, Harvard, Vancouver, ISO, and other styles

19

Bafail, Rawan SM. "Disintegration testing for orally disintegrating tablets (ODTs): An overview." Tropical Journal of Pharmaceutical Research 22, no. 11 (2024): 2399–406. http://dx.doi.org/10.4314/tjpr.v22i11.21.

Full text

Abstract:

Prescribing orally disintegrating tablet (ODT) dosage form is a common practice. For several populations, including geriatrics and pediatrics, ODTs are one of the most desired dosage forms. They are solid dosage forms designed to disintegrate or dissolve very quickly in contact with saliva as soon as they are placed in oral cavity of a patient. According to United States Pharmacopeia (USP), every dosage form has to pass some quality control tests to ensure uniformity and performance of this dosage form. For ODTs, disintegration test is fundamental to ascertain time required for tablets to brea

APA, Harvard, Vancouver, ISO, and other styles

20

ÖZYILMAZ, Emine Dilek, and Tansel ÇOMOĞLU. "Overview on the Orally Disintegrating Tablet Formulations." Journal of Literature Pharmacy Sciences 8, no. 2 (2019): 97–107. http://dx.doi.org/10.5336/pharmsci.2018-63119.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Tok, Yağmur Pirinçci, Burcu Mesut, and Yıldız Özsoy. "Design, Preparation, and Evaluation of Taste-Masked Dexketoprofen of Orally Disintegrating Tablet by Using QbD Approach." Proceedings 78, no. 1 (2020): 30. http://dx.doi.org/10.3390/iecp2020-08675.

Full text

Abstract:

The present investigation was carried out to develop a taste-masked, orally disintegrating tablet containing Dexketoprofen for evaluating the effect of the coating amount on the product’s quality attributes via Quality by Design (QbD) systematical roadmap. Dexketoprofen, S(+)-enantiomer of bitter taste ketoprofen, involves an arylalkil group which is the most frequently used analgesic in the management of acute and chronic pain. To overcome of bitter-taste of the active pharmacological ingredients should apply a taste-masking approach. For this purpose, the bitter taste dexketoprofen particles

APA, Harvard, Vancouver, ISO, and other styles

22

Shamling, Sakhare Sfurti, Siddhi Chavan, Gurav Poonam Chandrakant, Rutuja Tanaji Kharat, and Ajit Shankarao Kulkarni. "Isolation, Characterization, Chemical Modification and Application of Echinochloa Colona Starch as Tablet Disintegrant." International Journal of Pharmaceutical Sciences and Nanotechnology 14, no. 4 (2021): 5529–37. http://dx.doi.org/10.37285/ijpsn.2021.14.4.2.

Full text

Abstract:

Oral disintegrating tablets are solid dosage form containing medical substances which disintegrate rapidly, usually within few seconds when placed upon tongue requiring no additional water to facilitate swallowing. Solid dosage forms that can be disintegrated, dissolved, or suspended by saliva in the mouth resulting in easy swallowing can provide significant benefits to the pediatric and geriatric population, as well as other patients who prefer the convenience of easily swallowable dosage forms Superdisintegrants are currently approached and utilized in the formulation of the orally disintegr

APA, Harvard, Vancouver, ISO, and other styles

23

A., Deevan Paul* P. Nagaraj E. Reshma T. Mahesh Y. Divyasree. "CHALLENGES IN NANOTECHNOLOGY DRUG DELIVERY SYSTEMS - STATE OF ART TECHNOLOGIES." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1550–58. https://doi.org/10.5281/zenodo.816203.

Full text

Abstract:

The potential challenges to solve the poor solubility, limited chemical stability in vitro and in vivo after administration (i.e. short half-life), poor bioavailability and potentially strong side effects requiring drug enrichment at the site of action (targeting). This review describes the use of nanoparticulate carriers, developed in our research group, as one solution to overcome the dosage forms. The performance of ODTs depends on the technology used in their manufacture. The orally disintegrating property of these tablets is attributable to the quick ingress of water into the tablet matri

APA, Harvard, Vancouver, ISO, and other styles

24

Al-dhahir, Rasha Khalid, and Myasar Al-kotaji. "FORMULATION OF ORALLY DISINTEGRATING TABLETS OF CINNARIZINE BY USING DIRECT COMPRESSION METHOD." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 117. http://dx.doi.org/10.22159/ijap.2019v11i1.29599.

Full text

Abstract:

Objective: The aim of this work was to formulate and evaluate orally disintegrating tablets of cinnarizine that were prepared by direct compression method using different types of diluents and super disintegrants. The rationale behind this work was to accelerate the disintegration of the tablet to provide rapid dissolution, quick action and enhanced bioavailability of the drug.Methods: The tablets were prepared by direct compression method using different types of diluents as mannitol, microcrystalline cellulose (MCC), and lactose. Different super disintegrants were used such as crospovidone (

APA, Harvard, Vancouver, ISO, and other styles

25

Iancu, Valeriu, Florentina Roncea, Radu George Cazacincu, and Dumitru Lupuleasa. "Preparation and evaluation of diclofenac sodium orally disintegrating tablets." Ovidius University Annals of Chemistry 27, no. 1 (2016): 58–61. http://dx.doi.org/10.1515/auoc-2016-0004.

Full text

Abstract:

Abstract Orally disintegrating tablets (ODTs) are dosage forms which disintegrate in mouth within seconds without need of water. This type of quality in dosage form can be attained by addition of different varieties of excipients. Pharmaburst™ 500 is a co-processed excipient system which allows rapid disintegration and low adhesion to punches. The aim of the present study was to develop and evaluate 25 mg diclofenac sodium ODTs (orodispersible tablets) batches by direct compression method at different compression forces 10 kN (F1) and 20 kN (F2) and directly compressible excipients used in dif

APA, Harvard, Vancouver, ISO, and other styles

26

Parfati, Nani, Karina Citra Rani, and Meilany Meilany. "THE EFFECT OF COPROCESSED SUPERDISINTEGRANTS RATIO (CROSPOVIDONE-SODIUM STARCH GLYCOLATE) TO THE PHYSICOCHEMICAL CHARACTERISTICS OF ATENOLOL ORALLY DISINTEGRATING TABLETS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (2018): 318. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.23010.

Full text

Abstract:

Objective: The objective of this study was to evaluate the effect of coprocessed superdisintegrants (crospovidone-sodium starch glycolate) ratio 1:1; 1:2; and 1:3 to the physicochemical characteristics of atenolol orally disintegrating tablets.Methods: Orally disintegrating tablets of atenolol were prepared by direct compression method. There were three formulas which using three different ratios of coprocessed superdisintegrants (crospovidone-sodium starch glycolate). The ratio of coprocessed superdisintegrants were, 1:1 (formula 1); 1:2 (formula 2); and 1:3 (formula 3). Evaluation of the for

APA, Harvard, Vancouver, ISO, and other styles

27

Swarupa, Arvapalli* D. Swamy Shyamala. "ORAL DISINTEGRATION TABLETS – AN UPDATED REVIEW." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6926–34. https://doi.org/10.5281/zenodo.2617331.

Full text

Abstract:

<em>The purpose of writing this review is Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. It is leads to development of orally disintegrating tablets. This disintegrates in the mouth in seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. The prepared tablets were evaluated for hardness, friability, disintegration time

APA, Harvard, Vancouver, ISO, and other styles

28

Chono, Sumio, Megumi Matsui, and Katsuki Nakamura. "Effect of water temperature on a simple suspension method for lansoprazole orally disintegrating tablets." Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector 15, no. 1 (2019): 4–9. http://dx.doi.org/10.1177/1741134319826399.

Full text

Abstract:

In this study, we examined the physical properties, including disintegration, passage through a nasogastric administration tube, and acidoresistance, of one branded and five generic formulations of lansoprazole orally disintegrating (OD) tablets containing enteric-coated granules to examine the feasibility of a simple suspension method. The generic tablets immediately disintegrated in warm (55°C) and lukewarm water (35°C) and released the enteric-coated granules, which passed through an administration tube. Moreover, the released enteric-coated granules were stable under a simulated gastric ac

APA, Harvard, Vancouver, ISO, and other styles

29

Pramod, Prakash Ronge* Dr. A.D. Shinde. "A REVIEW ON –FORMULATION AND IN-VITRO EVALUATION OF ORODISPERSIBLE TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 10991–1000. https://doi.org/10.5281/zenodo.3234069.

Full text

Abstract:

<em>Recent advances in novel drug delivery (NDDS) aims to enhance the safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance.</em><em> Orodispersible tablet is advanced and convenient drug delivery system, now days acquiring the most widely accepted dosage form. The recent advance in NDDS aimed for the development of dosage forms convenient to manufacturing and administration, immediate release and increased bioavailability.</em> <em>Orally disintegrating tablets are solid dosage forms containing drug tha

APA, Harvard, Vancouver, ISO, and other styles

30

Chono, Sumio, Eno Yamada, Megumi Matsui, Takuma Sato, and Ryoya Kasai. "Physicochemical qualities and ingestibility of high value-added amlodipine besilate formulations." Journal of Generic Medicines: The Business Journal for the Generic Medicines Sector 13, no. 1 (2016): 28–33. http://dx.doi.org/10.1177/1741134316673225.

Full text

Abstract:

Objectives The physicochemical qualities and ingestibility of high value-added amlodipine besilate formulations were evaluated using one brand name and four generic orally disintegrating tablets (formulations A, B, C, D, and E) and a generic orally disintegrating film (formulation F). Methods Pushing out from a press-through package, tablet strength, and hydrophilia were examined for the aforementioned formulations A–E, and sensory characteristics according to the disintegration time, taste, and palatability in healthy subjects were evaluated for formulations A–F. Results The strength required

APA, Harvard, Vancouver, ISO, and other styles

31

Fitriana Priyoni, Nandhary, Apt Fahjar Prisiska, and Anisa Amalia. "Penggunaan Superdisintegrant Crospovidone Pada Sediaan Orally Disintegrating Tablet (ODT)." Syntax Literate ; Jurnal Ilmiah Indonesia 7, no. 9 (2024): 15974–83. http://dx.doi.org/10.36418/syntax-literate.v7i9.12839.

Full text

Abstract:

Orally Disintegrating Tablet (ODT) merupakan tablet yang bekerja cepat, mudah hancur dalam waktu kurang dari 60 detik, tidak meninggalkan rasa yang tidak enak di mulut ketika hancur dan praktis untuk dibawa berpergian. Komponen yang mempengaruhi waktu hancur tablet adalah superdisintegrant. Salah satu superdisintegrant yang banyak digunakan dalam pembuatan ODT adalah crospovidone. Tujuan dari studi literatur ini adalah untuk mengkaji pengaruh penggunaan crospovidone sebagai superdisintegrant terhadap sifat fisik ODT. Metode yang digunakan dalam tinjauan pustaka adalah narrative review yang men

APA, Harvard, Vancouver, ISO, and other styles

32

Parfati, Nani, Karina Citra Rani, Valencia Geovanny та Dewa Putu Pradnya Paramartha. "Formulasi Orally Disintegrating Tablet Atenolol-β-siklodekstrin menggunakan Co-process Superdisintegran Crospovidone- Sodium Starch Glycolate". MPI (Media Pharmaceutica Indonesiana) 1, № 4 (2018): 197–203. http://dx.doi.org/10.24123/mpi.v1i4.771.

Full text

Abstract:

Atenolol-β siklodekstrin sebagai obat anti hipertensi, merupakan rekayasa materi atenolol, yangmempunyai kelarutan kecil. Atenolol-β-siklodekstrin diharapkan mempunyai pelarutan yang besar, sehinggabioavailabilitas meningkat, demikian juga untuk efektivitas terapinya. Orally disintegrating tablet adalahbentuk sediaan yang dapat diterima untuk meningkatkan disolusi dengan mempercepat waktu hancur padamedia saliva. Karakter tablet yang cepat hancur dan larut dalam media yang sedikit, hal tersebut aseptabeluntuk penderita geriatrik. Co-process superdisintegran crospovidone-sodium starch glycolate

APA, Harvard, Vancouver, ISO, and other styles

33

Al Zomor, Abdulkarim K., and Mohammed A. Al Nethary. "Formulation and Evaluation of Molexicam Orally Disintegrating Tablet (ODT)." Thamar University Journal of Natural & Applied Sciences 4, no. 4 (2023): 41–48. http://dx.doi.org/10.59167/tujnas.v4i4.1292.

Full text

Abstract:

The aim of the present study was to develop and evaluate an oral disintegrant tablet of meloxicam. Drug delivery systems became sophisticated and pharmaceutical scientists acquire a better understanding of the physicochemical and biochemical parameters pertinent to their performance. Over the past three decades, mouth dissolving or orally disintegrating tablets have gained considerable attention as a preferred alternative to conventional tablets due to better patient compliance.  Orally is the most preferable route of drug administration which has some limited to drug candidate that show

APA, Harvard, Vancouver, ISO, and other styles

34

DEMİRTÜRK, Esra, Deniz ONAN, and Tilbe ÇEVİKELLİ. "Evaluation of Orally Disintegrating Tablet Formulations in The Treatment of Oral Mucositis." Cukurova Anestezi ve Cerrahi Bilimler Dergisi 6, no. 3 (2023): 406–10. http://dx.doi.org/10.36516/jocass.1355644.

Full text

Abstract:

Aim: Orally disintegrating tablets (ODT) are widely used dosage forms with high patient compliance, which preferred in the treatment of many diseases currently. In this study we aimed to develop an orally disintegrating tablet formulation can be preferred in the treatment of oral mucositis, which often occurs after chemotherapy during cancer treatment. Methods: Lidocaine hydrochloride, which is a local anesthetic substance, was used as active pharmaceutical ingredient to obtain ODT formulation for the treatment of oral mucositis. ODTs were prepared by direct compression technique and cro

APA, Harvard, Vancouver, ISO, and other styles

35

Dhananjay, Patil Momin Sanaurrehman* Vinod Bairagi Abdurrahman Mohammed Awais Shrivastav Karishma Rajashri More. "FORMULATION DEVELOPMENT AND EVALUATION OF FAMCICLOVIR ORALLY DISINTEGRATING TABLET." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 09 (2018): 8427–39. https://doi.org/10.5281/zenodo.1411930.

Full text

Abstract:

Orally disintegrating systems have an edge amongst the oral drug delivery systems due to the highest component of compliance they enjoy in patients especially the geriatrics and pediatrics. In addition, patients suffering from dysphagia, motion sickness, repeated emesis and mental disorders prefer these medications because they cannot swallow large quantity of water. Further, drugs exhibiting satisfactory absorption from the oral mucosa or intended for immediate pharmacological action can be advantageously formulated in these dosage forms. However, the requirements of formulating these dosage

APA, Harvard, Vancouver, ISO, and other styles

36

Manohari, Packiaraj Jeyachandran, Aswin Iyappan Seethalakshmi, Samuel George, et al. "Development Pharmaceutics of Doxepin Hydrochloride Orally Disintegrating Tablets for Dosing Flexibility to Physicians and Patient Compliance." Journal of Drug Delivery and Therapeutics 14, no. 12 (2024): 45–59. https://doi.org/10.22270/jddt.v14i12.6909.

Full text

Abstract:

An attempt was made to formulate, evaluate and commercialize Doxepin Hydrochloride orally disintegrating tablets 3 mg, 6 mg, 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg. A direct blending and compression process by scale-up and scale-down approach / dose-proportional approach was followed to make the product. The excipients include 55% of Pearlitol Flash (Co-processed excipient of 80% D-Mannitol & 20% Maize Starch), 18% of Ludipress (Co-processed excipient of 93% Lactose Monohydrate, 3.5% Povidone K30 & 3.5% Polyplasdone XL), 0.2% of Peppermint Flavor 501500 TP0504, 0.4% of Sucralose an

APA, Harvard, Vancouver, ISO, and other styles

37

HS, Bhandari, and Wagh RD. "Development and assessment of Carboxymethylated Galactomannan from Seeds of Caesalpinia pulcherrima as an Efficient Disintegrating Agent for Orally Disintegrating Tablet." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1217–24. https://doi.org/10.25258/ijddt.14.4.39.

Full text

Abstract:

Current study's objective was to evaluate the disintegration potential of naturally occurring Caesalpinia pulcherrima seedgalactomannan and to chemically modify it for formulation of orally disintegrating tablet formulation. Galactomannan extracted from the Caesalpinia pulcherrima seeds received chemical modification through carboxymethylation in an effort to enhance its hydrophilic nature of galactomannan which enhances disintegration potency. Carboxymethylated Caesalpinia pulcherrima seed galactomannan synthesized by etherification process by using monochloroacetic acid the titrimetric metho

APA, Harvard, Vancouver, ISO, and other styles

38

Comoglu, Tansel. "Orally disintegrating tablets (ODTs): An innovative approach to tablet formulations." Macedonian Pharmaceutical Bulletin 68, no. 03 (2022): 25–26. http://dx.doi.org/10.33320/maced.pharm.bull.2022.68.03.009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Gupta, Anil K., Charanjeet Singh, Yashwant ., and Kamal . "Formulation Optimization and Evaluation of Orally Disintegrating Tablets of Moxifloxacin." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 04 (2022): 1658–62. http://dx.doi.org/10.25258/ijddt.12.4.30.

Full text

Abstract:

Oral administration of a pharmacologically active agent is the common and most preferred route among patients suffering from different types of illness. In the market, different type of oral dosage form is available among them tablet is the most favorite and demanded formulation. Further, the tablets, which are easy to use and swallow, are the ideal dosage form like orally disintegrating tablets (ODT’s). The main advantage of this type of formulation is that they can give easily to old aged and under-aged patients. In this research work, ODT’s formulation was manufactured, which get easily dis

APA, Harvard, Vancouver, ISO, and other styles

40

M, K. Aneebuddin, and Kumar Prajwal. "Recent Trends in the Chemistry of Polymers used in Oral Drug Delivery Systems." Chemistry Research Journal 7, no. 6 (2022): 97–106. https://doi.org/10.5281/zenodo.11533254.

Full text

Abstract:

<strong>Abstract </strong>Tablet is one of the utmost chosen dosage forms administered orally<strong>.</strong> Disintegrants are substances added to tablets and some encapsulated preparations to encourage the breaking up of both tablet and capsule "slugs" into smaller fragments in an aquatic environment. This increases the surface area that is available and speeds up the release of the drug component. They increase moisture penetration and distribution of the tablet matrix. Tablet disintegration has attracted a lot of attention as an important stage in achieving rapid drug release. The concen

APA, Harvard, Vancouver, ISO, and other styles

41

Motokazu, Iwata. "Design of Fast Disintegrating Tablets and Orally Disintegrating Tablet by Reduction of Hydrophobic Lubricant." MEMBRANE 38, no. 1 (2013): 57–61. http://dx.doi.org/10.5360/membrane.38.57.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Lou, Hao, Min Liu, Wen Qu, et al. "Evaluation of Chlorpheniramine Maleate microparticles in orally disintegrating film and orally disintegrating tablet for pediatrics." Drug Development and Industrial Pharmacy 40, no. 7 (2013): 910–18. http://dx.doi.org/10.3109/03639045.2013.789907.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Putri, Arine Astika, Desy Nawangsari, and Khamdiyah Indah Kurniasih. "FORMULASI SEDIAAN ORALLY DISINTEGRATING TABLET (ODT) ASPIRIN DENGAN SODIUM STARCH GLYCOLATE SEBAGAI SUPERDISINTEGRANT." Pena Medika : Jurnal Kesehatan 14, no. 1 (2024): 407–17. https://doi.org/10.31941/pmjk.v14i1.3713.

Full text

Abstract:

Aspirin adalah NSAID salisilat yang digunakan sebagaiagen antiplatelet dalam pengobatan stroke. Kematianakibat stroke dalam waktu 5 tahun, lebih dari separuhpasien stroke berusia dangt; Seorang berusia 45 tahunyang meninggal. Banyak pasien lanjut usia yang tidak maumenerima/mengonsumsi tablet karena takut tersedak ataukesulitan menelan. Tablet yang hancur secara oral (ODT) adalah sediaan yang lebih cepat hancur, hancur dalamwaktu kurang dari 60 detik bila dimasukkan ke dalammulut, dan tidak memerlukan tambahan air untuk ditelan. Tujuan penelitian ini adalah untuk mengetahui pengaruhkonsentrasi

APA, Harvard, Vancouver, ISO, and other styles

44

Binti Sarun, Nur Hanisah, Archadian Nuryanti, and Ika Dewi Ana. "The Effect of Chitosan Concentration on Disintegration Time of Amoxicillin Tablet." Key Engineering Materials 884 (May 2021): 298–303. http://dx.doi.org/10.4028/www.scientific.net/kem.884.298.

Full text

Abstract:

The most often prescribed antibiotics by dentists to patients is Amoxicillin. It is usually in the form of capsules and tablets which are hard to swallow, especially for geriatric and pediatric patients. Orally disintegrating tablet (ODT) with the capability to disintegrate inside oral cavity without the need of water required disintegrant agent in its formulation. In this study, chitosan as the product of deacetylation of chitin which originated from exoskeleton of crustacean shells was considered as suitable disintegrant because its swelling characteristic. The aim of this research was to st

APA, Harvard, Vancouver, ISO, and other styles

45

Prabhat, Shrestha, Shrestha Rajan, and Shrestha Sahana. "Formulation and evaluation of orally disintegrating tablet containing taste masked mirtazapine." Journal of Analytical & Pharmaceutical Research 10, no. 2 (2021): 71–80. http://dx.doi.org/10.15406/japlr.2021.10.00368.

Full text

Abstract:

Objective: This study aims to prepare the taste-masked granules of Mirtazapine by mass extrusion technique and formulate it into an oral dispersible tablet using different super disintegrates. Methods: Taste masked granules of mirtazapine were prepared by mass extrusion technique using Eudragit EPO in different ratios. The drug-polymer ratio was optimized based on the percent drug release in SSF and SGF. Taste masking efficacy of drug-polymer complex was determined by developing the bitterness threshold value of Mirtazapine. The selected drug-polymer complex was formulated into an oro-dispersi

APA, Harvard, Vancouver, ISO, and other styles

46

Attar, S. M., S. M. Ghurghure, and Sumit. "Teneligliptin hydrobromide hydrate mouth dissolving strip: Formulation and evaluation." International Journal of Pharmaceutical Chemistry and Analysis 11, no. 2 (2024): 164–70. http://dx.doi.org/10.18231/j.ijpca.2024.023.

Full text

Abstract:

Oral route is considered as one of the most convenient route for administration of various pharmaceutical dosage form like tablet, capsule, syrup, suspension and emulsion. Fast Dissolving Drug Delivery systems have developed various fast disintegrating preparations like Oral disintegrating film, ODF. Oral disintegrating film is the solid oral drug delivery system, in which water soluble polymer involve to disintegrate film into mouth fastly. Oral disintegrating film is superior as compare to orally disintegrating tablet as the cost of production is low. The present research was undertaken to d

APA, Harvard, Vancouver, ISO, and other styles

47

Jain, P., A. Mishra, and A. Pathak. "PREPARATION & EVALUATION OF ORODISPERSIBLE TABLET CONTAINING ASPIRIN BY SUBLIMATION METHOD." INDIAN DRUGS 52, no. 12 (2015): 60–62. http://dx.doi.org/10.53879/id.52.12.10465.

Full text

Abstract:

Orodispersible tablets are uncoated tablets which when taken into the mouth, get easily dispersed within 3 min before swallowing. they are also known as orally disintegrating tablets, mouth-dissolving tablets, rapid dissolving tablets fast-disintegrating tablets, fast-dissolving tablets. In this work, sublimation process was used to prepare orodispersible tablets of aspirin by formulating various batches using different concentration of sodium starch glycolate, camphor and cross povidone. An effort was made by using two modes, first, to increase water uptake for the fast dispersion by creating

APA, Harvard, Vancouver, ISO, and other styles

48

Karanam, Fathima Nilesh Kadiyala Arun Kumar2 B.T.N.Vamsi Krishna. "FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ACECLOFENAC BY USING ISPAGHULA HUSK POWDER AS NATURAL SUPER DISINTEGRANT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1793–801. https://doi.org/10.5281/zenodo.1210762.

Full text

Abstract:

Fast disintegrating tablets (FDTs) are meant for administration to the patients who cannot swallow, such as elderly, stroke victims, bedridden patients, patients affected by renal failure, and the patients who refuse to swallow, such as pediatric, geriatric, and psychiatric patients. The present study is aimed to prepare orally disintegrating tablet of a model drug – Aceclofenac, using Ispaghula powder as natural super disintegrant, to conduct incompatibility studies by using Fourier-transform infrared spectroscopy (FTIR), to evaluate the prepared tablets for weight variation, friability

APA, Harvard, Vancouver, ISO, and other styles

49

Budipratiwi Wisudyaningsih, Lusia Oktora Kumala Sari, and Tiara Puspita Arisanti. "OPTIMASI SODIUM STARCH GLYCOLATE DAN POLYVINYLPYRROLIDONE K-30 DALAM SEDIAAN ORALLY DISINTEGRATING TABLET SALBUTAMOL SULFAT." Jurnal Kesehatan Islam : Islamic Health Journal 12, no. 2 (2023): 19–27. http://dx.doi.org/10.33474/jki.v12i2.20838.

Full text

Abstract:

ABSTRACT Difficulty in swallowing drug and slow onset of action of drug are common problems of conventional tablet. Orally disintegrating tablet (ODT) is an innovative dosage form to overcome the problem of swallowing drug and provide quick onset of action of drug because it can disintegrates quickly when contact with saliva in less than 3 minutes. This study formulate and evaluate ODT containing salbutamol sulphate to relieve the respiratory disorders immediately. Materials that affect the disintegration time of ODT are superdisintegrants and binders. Sodium Starch Glycolate (SSG) is a superd

APA, Harvard, Vancouver, ISO, and other styles

50

Aniket G. Karodade, Aniket P. Wable, Gopal kharbal, Sunil S. Bhagat, and Swati P. Deshmukh. "Fast dissolving tablet." GSC Biological and Pharmaceutical Sciences 27, no. 1 (2024): 001–7. http://dx.doi.org/10.30574/gscbps.2024.27.1.0096.

Full text

Abstract:

Fast dissolving tablets have emerged as a popular dosage form, particularly beneficial for pediatric and geriatric patients facing challenges such as dysphagia or hand tremors. These tablets dissolve quickly in saliva without needing water, enhancing compliance and effectiveness of therapy. They offer advantages like easy portability, accurate dosing, and improved bioavailability. Various technologies, including spray drying and melt granulation, have been developed for their manufacturing. This review provides comprehensive information on fast dissolving tablets, covering their definition, ad

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!