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Relevant bibliographies by topics / Orally Disintegrating Tablets (ODTs)

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Journal articles
Dissertations / Theses
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Academic literature on the topic 'Orally Disintegrating Tablets (ODTs)'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Orally Disintegrating Tablets (ODTs)"

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Eremin, V. A., E. V. Blynskaya, and V. V. Bueva. "Orally disintegrating tablets: mechanisms, preparation methods, problems and achievements." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 6 (December 19, 2023): 25–32. http://dx.doi.org/10.33920/med-13-2306-03.

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The oral route of drug administration is considered one of the preferred delivery methods. In recent years, orally disintegrating tablets (ODTs) have become convenient pharmaceutical dosage forms, especially for specific patient populations such as pediatric, geriatric, and psychiatric patients with dysphagia. Rapid disintegration and increased bioavailability are some of the essential characteristics of ODTs that make them superior to other traditional pharmaceutical dosage forms. Orally disintegrating tablets are pills that disintegrate within a few seconds after being placed in the oral cav

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Bafail, Rawan SM. "Disintegration testing for orally disintegrating tablets (ODTs): An overview." Tropical Journal of Pharmaceutical Research 22, no. 11 (2024): 2399–406. http://dx.doi.org/10.4314/tjpr.v22i11.21.

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Prescribing orally disintegrating tablet (ODT) dosage form is a common practice. For several populations, including geriatrics and pediatrics, ODTs are one of the most desired dosage forms. They are solid dosage forms designed to disintegrate or dissolve very quickly in contact with saliva as soon as they are placed in oral cavity of a patient. According to United States Pharmacopeia (USP), every dosage form has to pass some quality control tests to ensure uniformity and performance of this dosage form. For ODTs, disintegration test is fundamental to ascertain time required for tablets to brea

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Shashank, Khailkhura, Singh Bhavana, Joshi Deepika, and Semwal Nidhi. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. https://doi.org/10.5281/zenodo.7180875.

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Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

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Eremin, V. A., and E. V. Blynskaya. "Modern approaches to assessing the quality of orally disintegrating tablets." Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology), no. 6 (December 19, 2023): 8–17. http://dx.doi.org/10.33920/med-13-2306-01.

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Orally disintegrating tablets (ODTs) are the preferred and accepted solid dosage forms by patients. These tablets disintegrate in the oral cavity within a short period, providing an advantage for individuals who have difficulty swallowing. Quality control of ODTs can be achieved through measures such as friability, porosity, hardness, wetting time, water absorption capacity, in vitro disintegration test, and dissolution test. This article summarizes the advantages and in vitro quality control tests of orally disintegrating tablets.

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Shashank Khailkhura, Bhavana Singh, Deepika Joshi, and Nidhi Semwal. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0124.

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Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

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Mahrous, Gamal Mohamed, Mohamed Gabr Kassem, Mohamed Abbas Ibrahim, and Sayed Hassan Auda. "Formulation and evaluation of orally disintegrating clopidogrel tablets." Brazilian Journal of Pharmaceutical Sciences 52, no. 2 (2016): 309–18. http://dx.doi.org/10.1590/s1984-82502016000200009.

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ABSTRACT Recent advances in drug delivery systems have aimed to achieve better patient compliance. One of these advances is the formulation of orally disintegrating tablets (ODTs) that dissolve instantaneously, releasing drugs within a few seconds without the need of water. The main objective of this paper was to prepare and develop ODTs of clopidogrel. The ODTs were prepared by direct compression. The effect of three superdisintegrants, namely crospovidone, croscarmellose sodium, and sodium starch glycolate, using three different disintegration times on the dissolution rate was investigated.

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Dang, Yen N. T., Phuong H. L. Tran, and Thao T. D. Tran. "Development of the Modified Ocimum gratissimum Seeds for Orally Disintegrating Tablets." Recent Patents on Drug Delivery & Formulation 14, no. 1 (2020): 40–47. http://dx.doi.org/10.2174/1872211313666191029144038.

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Background: Natural materials have been encouraged in controlled drug release and improved drug bioavailability. Objective: This study aimed to develop a modification process for the use of a natural material, Ocimum gratissimum seeds (OGS), in Orally Disintegrating Tablets (ODTs). Methods: The OGS was investigated with four different modification processes including only milling, swelling, swelling/milling, and swelling/milling/incubation. The ODTs containing the modified OGS as a disintegrant were prepared by the wet granulation method. Furthermore, an evaluation to assess parameters of tabl

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Swarupa, Arvapalli* D. Swamy Shyamala. "ORAL DISINTEGRATION TABLETS – AN UPDATED REVIEW." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6926–34. https://doi.org/10.5281/zenodo.2617331.

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<em>The purpose of writing this review is Oral delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. It is leads to development of orally disintegrating tablets. This disintegrates in the mouth in seconds without chewing and the need of water which is advantageous mainly for pediatrics, geriatrics and patients having difficulty in swallowing tablets and capsules. The prepared tablets were evaluated for hardness, friability, disintegration time

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Iancu, Valeriu, Florentina Roncea, Radu George Cazacincu, and Dumitru Lupuleasa. "Preparation and evaluation of diclofenac sodium orally disintegrating tablets." Ovidius University Annals of Chemistry 27, no. 1 (2016): 58–61. http://dx.doi.org/10.1515/auoc-2016-0004.

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Abstract Orally disintegrating tablets (ODTs) are dosage forms which disintegrate in mouth within seconds without need of water. This type of quality in dosage form can be attained by addition of different varieties of excipients. Pharmaburst™ 500 is a co-processed excipient system which allows rapid disintegration and low adhesion to punches. The aim of the present study was to develop and evaluate 25 mg diclofenac sodium ODTs (orodispersible tablets) batches by direct compression method at different compression forces 10 kN (F1) and 20 kN (F2) and directly compressible excipients used in dif

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Kashiwagura, Yasuharu, Shota Takusagawa, Yasuyuki Ikematsu, Shimako Tanaka, Noriyuki Namiki, and Shinya Uchida. "Tablet characteristics and pharmacokinetics of orally disintegrating tablets containing coenzyme Q10 granules prepared by different methods." Acta Pharmaceutica 73, no. 1 (2023): 107–19. http://dx.doi.org/10.2478/acph-2023-0007.

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Abstract This study aimed to elucidate the characteristics and pharmacokinetics of orally disintegrating tablets (ODTs) containing coenzyme Q10 (CoQ10) granules prepared by spray drying, hot-melting, and wet granulation. The hardness and disintegration times of CoQ10-ODTs containing 5 % crospovidone were 61.6–81.8 N and < 30 s, respectively; these values indicate that the as-prepared ODTs were adequate for clinical use. The hardness and disintegration times of all ODTs did not change significantly after a 28-day storage period at 30 °C/10 % relative humidity (RH), but storage under high tem

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Dissertations / Theses on the topic "Orally Disintegrating Tablets (ODTs)"

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Chillas, Stephanie M. "The Formulation and Evaluation of Orally Disintegrating Tablets: Diphenhydramine HCl." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1371774622.

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Alanezi, Abdulkareem Ali. "Development of an Orally Disintegrating Mini-Tablet (ODMTs) Containing Metoclopramide HCl to Enhance Patient Compliance." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1417861431.

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Graben, Roger Dale Parsons Daniel L. "Promethazine orally disintegrating tablet." Auburn, Ala., 2006. http://hdl.handle.net/10415/1317.

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Jones, Rhys. "Formulation and process engineering of freeze-dried orally disintegrating tablets." Thesis, Aston University, 2013. http://publications.aston.ac.uk/19541/.

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Orally disintegrating tablets (ODTs) which are also referred to as orodispersible and fast disintegrating tablets, are solid oral dosage forms which upon placing on the tongue, disperse/disintegrate rapidly before being swallowed as a suspension or solution. ODTs are therefore easier and more convenient to administer than conventional tablets and are particularly beneficial for paediatric and geriatric patients, who generally have difficulty swallowing their medication. The work presented in this thesis involved the formulation and process development of ODTs, prepared using freeze-drying. Gel

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Al-Husban, A. K. "Novel formulation strategies for the fabrication of lyophilised orally disintegrating tablets." Thesis, Aston University, 2011. http://publications.aston.ac.uk/13369/.

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Orally disintegrating Tablets (ODTs), also known as fast-disintegrating, fast-melt or fast-dissolving tablets, are a relatively novel dosage technology that involves the rapid disintegration or dissolution of the dosage form into a solution or suspension in the mouth without the need for water. The solution containing the active ingredients is swallowed, and the active ingredients are then absorbed through the gastrointestinal epithelium to reach the target and produce the desired effect. Formulation of ODTs was originally developed to address swallowing difficulties of conventional solid oral

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Dennison, Thomas. "Orally disintegrating tablets : formulation development, novel engineering solutions and fixed dose combinations." Thesis, Aston University, 2017. http://publications.aston.ac.uk/30817/.

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Orally disintegrating tablets (ODTs) are an attractive solid dosage form for patients who suffer from dysphagia, a difficulty in swallowing, which is particularly prevalent in paediatric and geriatric populations. ODTs and fixed dose combination (FDC) formulations are popular as they improve patient compliance and combination of the two has not previously been explored. The requirement for ODTs to disintegrate rapidly whilst also being mechanically robust means that high drug loading is a significant challenge. An ODT formulation for the betalactam antibiotic flucloxacillin was developed at do

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Al-Khattawi, Ali. "Excipient characterization and particle engineering to develop directly compressed orally disintegrating tablets." Thesis, Aston University, 2015. http://publications.aston.ac.uk/25299/.

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ODTs have emerged as a novel oral dosage form with a potential to deliver a wide range of drug candidates to paediatric and geriatric patients. Compression of excipients offers a costeffective and translatable methodology for the manufacture of ODTs. Though, technical challenges prevail such as difficulty to achieve suitable tablet mechanical strength while ensuring rapid disintegration in the mouth, poor compressibility of preferred ODT diluent Dmannitol, and limited use for modified drug-release. The work investigates excipients’ functionality in ODTs and proposes new methodologies for enhan

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Alyami, Hamad. "Paediatric patient centric development of novel processes for the formulation of orally disintegrating tablets." Thesis, Aston University, 2016. http://publications.aston.ac.uk/33120/.

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Following the European regulation for paediatric formulations, the demand for the production of paediatric dosage forms has escalated. Managing the clinical needs of children is challenging, especially as this must often be accomplished using adult medicine formulations. For this reason, further paediatric dosage forms need to be developed to address their clinical needs. There are various formulations which can be administered via the oral route including tablets, capsules, liquids and chewable tablets. It is essential to mention orally disintegrating tablets (ODTs) which have been a popular

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Koner, Jasdip. "Formulation strategies and engineering processes for orally disintegrating tablets : the importance of robustness and disintegration." Thesis, Aston University, 2017. http://publications.aston.ac.uk/33600/.

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Orally disintegrating tablets (ODTs) are a dosage form ideal for paediatric or geriatric patients as they disintegrate/disperse within the oral cavity. Direct compression manufacture of ODTs is increasing in popularity due to its cost effectiveness and use of traditional tableting equipment, however excipients are required to fulfil certain requirements to form robust, fast disintegrating tablets. Mannitol is a vital excipient for ODT manufacture due to its high palatability, however its fragmentation behaviour under compression leads to mechanically weak and friable tablets. The work in this

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Bürki, Kathrin Eva [Verfasser]. "Preparation of taste masked orally disintegrating tablets by compression of coated pellets / Kathrin E. Bürki." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1111558825/34.

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Book chapters on the topic "Orally Disintegrating Tablets (ODTs)"

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Comoglu, Tansel, and Fatemeh Bahadori. "Granulation and Production Approaches of Orally Disintegrating Tablets." In Handbook of Pharmaceutical Granulation Technology, 4th ed. CRC Press, 2021. http://dx.doi.org/10.1201/9780429320057-18-21.

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Ejeta, Fikadu. "Orally Disintegrating Tablets." In Dosage Forms - Innovation and Future Perspectives [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.109892.

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Research and development costs for a single new pharmaceutical that is introduced to the market are estimated to cost between $1 billion and $2 billion. Due to the high cost of development and the need to quickly access various technologies, it is more cost-effective (clinically and financially) to enhance current pharmaceuticals for potency, selectivity, drug metabolism, and dosing convenience before they reach the market. Orally dissolving tablets have been developed as a result. Pharmaceutical companies have created oral disintegrating tablets that dissolve or disintegrate in the mouth with

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"Orally Disintegrating Tablets." In Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition. CRC Press, 2013. http://dx.doi.org/10.1081/e-ept4-120050313.

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"Orally Disintegrating Tablets and Related Tablet Formulations." In Pharmaceutical Dosage Forms - Tablets. CRC Press, 2016. http://dx.doi.org/10.1201/b15115-36.

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"Orally Disintegrating Tablets and Related Tablet Formulations." In Pharmaceutical Dosage Forms - Tablets. CRC Press, 2008. http://dx.doi.org/10.3109/9781420020298-13.

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Kumar, Amit, Londhe Sachin Bhimrao, Abha Sharma, and Awesh K. Yadav. "Polymers in orally disintegrating tablets and orally dissolving films." In Polymers for Oral Drug Delivery Technologies. Elsevier, 2025. http://dx.doi.org/10.1016/b978-0-443-13774-7.00016-5.

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Sowmyasree, Golla Venkata. "Tablets." In A Text Book of Pharmaceutics for I Year Diploma in Pharmacy. THINKPLUS PHARMA PUBLICATIONS, 2024. http://dx.doi.org/10.69613/736rs621.

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Tablets are the most widely used solid dosage form in pharmaceutical practice, offering advantages such as precise dosing, stability, and patient convenience. This section explores the various types of tablets, including immediate-release, modified-release, and orally disintegrating tablets, each designed to meet specific therapeutic needs. The composition of tablets, including active ingredients and excipients such as diluents, binders, disintegrants, and lubricants, is discussed in detail. Tablet manufacturing processes, from wet granulation and dry granulation to direct compression, are exa

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Karpe, Manisha, Nikhil Mali, and Vilasrao Kadam. "Formulation Evaluation of Acyclovir Orally Disintegrating Tablets: A Brief Overview." In Advanced Concepts in Pharmaceutical Research Vol. 6. B P International, 2024. http://dx.doi.org/10.9734/bpi/acpr/v6/7604e.

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"Orasolv and Durasolv: Efﬁcient Technologies for the Production of Orally Disintegrating Tablets." In Modified-Release Drug Delivery Technology. CRC Press, 2002. http://dx.doi.org/10.1201/9780203910337-19.

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Singh, Aditya, Mohammad Saleem, Pankaj Kumar, Poonam Kumari, Durgesh Singh, and Shubhrat Maheshwari. "DENDRIMERS IN ALZHEIMER'S DISEASE: CURRENT STATE AND FUTURE DIRECTIONS." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 9. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn9ch13.

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Alzheimer's disease (AD), neuronal death, and synaptic loss are all characterized by extracellular amyloid-(A) plaques and neurofibrillary in the intracellular milieu, all of which lead to progressive cognitive impairment. The prevalence of AD exponentially rises after age 65, making age the most major risk factor for the disease. It is expected that during the next 20 years, the overall prevalence of AD will double as the average lifespan in emerging nation’s increases. Ideal drug delivery systems depend on the pharmacokinetics and pharmacodynamics of many innovative formulations to achieve t

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Conference papers on the topic "Orally Disintegrating Tablets (ODTs)"

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Szlęk, Jakub, Adam Pacławski, Natalia Czub, and Aleksander Mendyk. "Computational Intelligence Model of Orally Disintegrating Tablets: An Attempt to Explain Disintegration Process." In International Electronic Conference on Applied Sciences. MDPI, 2021. http://dx.doi.org/10.3390/asec2021-11163.

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