Academic literature on the topic 'Orbital Neoplasms, radiotherapy'

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Journal articles on the topic "Orbital Neoplasms, radiotherapy"

1

Vijayakumar, S., W. A. McCarthy, C. B. Schroy, F. J. Thomas, P. Thompson, P. D. Higgins, C. F. Lanzieri, P. M. Barrett, and M. Murray. "A Technique Using Electrons and Photons in the Radiotherapy of Orbital Neoplasms." Acta Oncologica 26, no. 6 (January 1987): 492–93. http://dx.doi.org/10.3109/02841868709113725.

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2

Vijitha, Vempuluru Sai, Anasua Ganguly Kapoor, Ruchi Mittal, and Ramakrishna Vangara. "Preoperative embolisation of orbital solitary fibrous tumour." BMJ Case Reports 13, no. 12 (December 2020): e235576. http://dx.doi.org/10.1136/bcr-2020-235576.

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Solitary fibrous tumours (SFT) is an encompassing terminology comprising of tumours with proliferating CD34 positive specialised fibroblasts. Orbital SFTs are rare slowly progressive highly vascular neoplasms. Complete surgical excision is considered the mainstay treatment. Incomplete resection is a known risk factor for recurrence and malignant transformation. Recently preoperative embolisation of SFT has shown promising results in reducing the vascularity of these tumours rendering them amenable to complete surgical excision. Less than 10 cases of embolisation of orbital solitary fibrous tumours have been described in literature. Our patient underwent an attempted surgical excision elsewhere with significant intraoperative haemorrhage which precluded its complete excision. Herein, we report successful outcome in a case of hypervascular orbital SFT managed with preoperative embolisation, surgical resection and adjuvant radiotherapy along with a review of relevant literature.
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3

Lindeman, Pontus, Ulf Eklund, and Björn Petruson. "Survival after surgical treatment in maxillary neoplasms of epithelial origin." Journal of Laryngology & Otology 101, no. 6 (June 1987): 564–68. http://dx.doi.org/10.1017/s0022215100102257.

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SummaryDuring 1968–1979, 55 cases of epithelial neoplasms originating from the maxillary antrum were diagnosed and treated within the referral area of 1.5 million inhabitants.A majority of the patients were operated upon after pre-operative irradiation therapy (40–50 Gy). No significant difference in survival rate was found between patients operated on by total maxillectomy, including orbital exenteration, and patients subjected to partial maxillectomy. Patients with tumours not completely removed during primary surgery and patients with glandular involvement had a poor prognosis despite additional surgery and radiotherapy. The prognosis for the remaining patients was considerably better, with a 5-year survival rate of 60 per cent.
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4

Vijayakumar, S., W. McCarthy, F. Thomas, C. Schroy, and P. Thompson. "Radiotherapy of orbital neoplasms: Advantages of using photons plus electrons with “anterior chamber” block." International Journal of Radiation Oncology*Biology*Physics 12 (November 1986): 101–2. http://dx.doi.org/10.1016/0360-3016(86)90524-9.

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5

Thomas, Giovana R., Jacinto J. Regalado, and Mark McClinton. "A Rare Case of Mucoepidermoid Carcinoma of the Nasal Cavity." Ear, Nose & Throat Journal 81, no. 8 (August 2002): 519–22. http://dx.doi.org/10.1177/014556130208100811.

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Mucoepidermoid carcinoma of the nasal cavity is rare. We report the case of a 57-year-old man who was evaluated for a rapidly enlarging subcutaneous mass on the nasal bridge. The tumor was diagnosed as a mucoepidermoid carcinoma. The patient underwent extensive surgical resection andpostoperative radiotherapy, but 5 months later he required orbital exenteration for persistent disease. Despite these radical measures, the patient died with persistent disease 9 months following the initial evaluation. The aggressive behavior of this tumor highlights the need for physicians to be aware of the differential diagnosis, symptoms, and signs of neoplasms that originate in the nasal cavity so that prompt treatment can be instituted.
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Arora, Rajender Singh, Anirudh Bhattacharya, Dwarkadas Adwani, and Sidak Singh Arora. "Massive Periocular Squamous Cell Carcinoma Engulfing the Globe: A Rare Case Report." Case Reports in Oncological Medicine 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/641086.

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The eyelid tumors are rare neoplasms in head and neck oncological practice. The maximum incidence is after sixty years and most of the tumors are situated in the lower eyelid and medial canthus. A wide range of clinical presentations contribute to a high risk of misdiagnosis. The factors such as very large lesions, incomplete excision, histopathologic features such as poor differentiation, multicentric origin, pagetoid spread, and delayed diagnosis are associated with poor prognosis. Because of different tissues at eyelid level, a variety of tumor types and subtypes can arise, but most of them are carcinomas. A rare case of eyelid carcinoma spreading and engulfing the whole of globe which was treated by orbital exenteration and postoperative radiotherapy is presented with a disease-free follow-up of 10 months which, considering its size, is extremely rare. The early diagnosis and proper treatment of such rare tumors still remain the mainstay to predict favourable prognosis.
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7

Musin, Sh I., N. А. Sharafutdinova, A. V. Sultanbaev, S. V. Osokin, B. A. Ibragimov, K. V. Menshikov, and R. T. Ayupov. "Hedgehog inhibitor in the treatment of basal cell skin cancer: case report." Head and Neck Tumors (HNT) 11, no. 1 (April 24, 2021): 109–14. http://dx.doi.org/10.17650/2222-1468-2021-11-1-109-114.

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Background. In the structure of malignant neoplasms, basal cell skin cancer (BCC) occupies a leading position. In the initial stages of a malignant neoplasm, the main treatments are local treatment methods, both surgical and radiation. However, in about 1.3 % of cases, BCC can become locally or metastatic in which local treatment methods are limited. With the development of targeted drugs, such as the Hedgehog pathway inhibitor, the possibilities for effective and safe treatment of this category of patients have appeared.The objective is to present the clinical case of treating a patient with BCC who is receiving systemic therapy with a Hedgehog signaling pathway inhibitor.Case report. According to the patient, a tumor in the lower eyelid of the left eye appeared in 2000, did not seek medical help. In 2011, he applied to the clinic and was diagnosed with skin cancer of the lower eyelid of the left eye T2bN0M0. The patient refused the proposed treatment. Reapplied only in June 2017 already with a locally distributed process. The case is recognized as unresectable. From June 30, 2017 to September 4, 2017, he underwent a course of a radical program of radiotherapy, with a positive effect. 07/01/2019, he relapsed with a relapse of an orbital tumor on the left. From July 16, 2019, the patient began taking the drug wismodegib 150 mg once a day. Against the background of the treatment, control CT studies on 11/24/2019 and 11/03/2020 compared with CT data from 07/09/2019 reduced the volume of the tumor by 78 and 82 %. The patient currently continues to take wismodegib.Conclusion. The clinical case demonstrates successful treatment of locally advanced basal cell skin cancer with a Hedgehog signaling pathway inhibitor.
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8

Porto Silva Costa, Isabela, Talita Trindade França, Ivelise Theresa Araujo Balby, Gustavo Henrique Campos de Sousa, and Luis Alves de Pinho Segundo. "Diagnostic and therapeutic approach to esthesioneuroblastoma: case report." Health Residencies Journal - HRJ 2, no. 12 (August 24, 2021): 56–66. http://dx.doi.org/10.51723/hrj.v2i12.162.

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Esthesioneuroblastoma is a rare neoplasm of the nervous system that appears in the paranasal cavities derived from the olfactory neuroepithelium, located in the cribriform region of the nasal fossa, and can invade the sinuses of the face, skull base and orbital region. Kadish classification is the most widely used to stage it according to its extension. The symptomatology is unspecific, and it may present progressive unilateral nasal obstruction, epistaxis, anosmia, headache, sinusitis, diplopia, and orbital proptosis. The diagnosis is based on the lesion biopsy, immunohistochemistry, and ultrastructural findings. Excision of the tumor is described as the treatment of choice that may be associated with radiotherapy and chemotherapy. This is a case report of an olfactory esthesioneuroblastoma in a patient admitted to the hospital complaining of orbital proptosis who, after a computed tomography of the skull, showed a suspicious lesion. After the biopsy and the anatomopathological study, a protocol with neoadjuvant chemotherapy was initiated, with the subsequent excision of the tumor. Despite the lack of other symptoms, an advanced stage of the neoplasm was identified, which reflects the importance of investigating less common complaints and thus facilitating the diagnosis and early treatment.
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9

Fasina, Oluyemi. "Ocular surface squamous neoplasia in Ibadan, Nigeria." Asian Journal of Oncology 01, no. 02 (July 2015): 101–5. http://dx.doi.org/10.4103/2454-6798.173312.

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ABSTRACT Introduction: Squamous cell carcinoma is the most common malignancy of the conjunctiva worldwide. Ocular surface squamous neoplasia (OSSN) describes the spectrum of ocular surface intraepithelial neoplasia, pre-invasive and invasive squamous cell carcinoma. Method: This nonrandomized study aims to describe the epidemiology, clinical features and evaluate the outcome of treatment in patients with histological diagnosis of OSSN managed at a single tertiary center in Ibadan, Nigeria. Result: Twenty-five patients were managed within the study period with a mean age of 42 ± 15.3 years and male: female ratio of 1:1.5. All patients presented with growth and redness, and, visual impairment was observed in seven (28%) patients. Fifteen (60%) patients were seropositive for HIV infection and one patient (4%) had xeroderma pigmentosum. The right side was involved in 11 (44%) patients and there were no bilateral lesions. Morphologically, 18 (72%) lesions were gelatinous, six (24%) were leucoplakic while one (4%) was nodular. Twenty-two (88%) patients underwent surgical excision with alcohol kerato-epitheliectomy and cryotherapy, while three (12%) patients had lid sparing orbital exenteration. The three (12%) patients with intraepithelial neoplasm, and six (24%) who had SCC but with tumor-free margins received no adjuvant treatment post-operatively, while 13 (52%) with SCC and microscopic margin involvement were treated with four courses of 0.04% topical mitomycin C (MMC) and the three (12%) patients who had orbital exenteration were referred for radiotherapy. The average follow-up period was 12 months, no patient was lost to follow-up and none has had recurrence. Conclusion: OSSN occurs in younger individuals, and is strongly associated with HIV infection in our environment. Early diagnosis and intervention can prevent severe ocular morbidity. Wide surgical excision with intra-operative cryotherapy and adjuvant treatment with topical MMC post-operatively seem to give good outcome in our patients.
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10

Gomes, Lilian Brito, Jonathan Dos Santos Lima, Valéria Camargo Silveira, Jacqueline Stephanie Fernandes Do Nascimento, Nicolle Dos Santos Moraes Nunes, Marco Orsini, Gilberto Canedo Martins Jr, et al. "Orbital Extramedullary Plasmacytoma: Case report and literature review." Gazette of Medical Sciences 2, no. 1 (February 1, 2021): 26–29. http://dx.doi.org/10.46766/thegms.ophthal.21020101.

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Extramedullary plasmacytoma is a rare disease, characterized histopathologically by infiltration of plasma cells of different maturities and producing monoclonal immunoglobulin outside the bone marrow. J.R.G., 52 years old, male, sought medical assistance due to amaurosis and blocked eye movements. We performed Magnetic Nuclear Resonance of the skull that showed discrete intermediate signal tissue, next to the optic nerve canal and homolateral superior orbital fissure, with slight extension to the lower orbital fissure, associated with thickening of the corresponding meninges, involving the proximal portion of the optic nerve, measuring 1.3 x 1.1 x 2.5 cm. Non-specific aspect, but suggestive of lymphoproliferative lesion. Right and extraorbital tumor excision was performed, in which it was not possible to completely resect the tumor. The anatomopathological examination of the piece showed a neoplasm of plasma cells (plasmacytoma). The diagnosis is made from the exclusion of Multiple Myeloma. The treatments of choice are radiotherapy, due to the high radiosensitivity in 80–100% of cases, and surgery for localized lesions.
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Books on the topic "Orbital Neoplasms, radiotherapy"

1

1930-, Sagerman Robert H., Alberti W, and Abramson David H, eds. Radiotherapy of intraocular and orbital tumors. 2nd ed. Berlin: Springer, 2003.

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2

H, Abramson David, Alberti W, and Sagerman Robert H. 1930-, eds. Radiotherapy of intraocular and orbital tumors. Berlin: Springer-Verlag, 1993.

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3

(Editor), R. H. Sagerman, and W. E. Alberti (Editor), eds. Radiotherapy of Intraocular and Orbital Tumors (Medical Radiology / Radiation Oncology). 2nd ed. Springer, 2002.

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