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Journal articles on the topic 'Organ recipient'

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1

Suddaby, Elizabeth C., Margaret J. Schaeffer, Lori E. Brigham, and Timothy R. Shaver. "Analysis of Organ Donors in the Peripartum Period." Journal of Transplant Coordination 8, no. 1 (1998): 35–39. http://dx.doi.org/10.1177/090591999800800108.

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This study was a retrospective review of 252 brain-dead potential donors from 1990 to 1996, including 5 organ donors in the peripartum period. The purpose of the study was to determine the effects of pregnancy on organ donor management and recipient outcome. Case analysis of 5 pregnant donors identified problems with hemodynamic stability and electrolyte abnormalities, including hypernatremia, hyperchloremia, and hypocalcemia. In addition, blood glucose was frequently elevated. Two donors were treated for diabetes insipidus. All 5 donors produced organs for 20 transplant recipients. Five heart
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Borović, Vladan, Saša Borović, Vida Drąsutė, and Dejan Rančić. "SECURE ORGAN TRANSPLANT INFORMATION SYSTEM." Facta Universitatis, Series: Automatic Control and Robotics 17, no. 1 (2018): 1. http://dx.doi.org/10.22190/fuacr1801001b.

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The heart of a modern and efficient information system is a computer database that can be accessed from all over the world. The system demands a strong protection and cryptography, due to a large number of threats in the electronic era. In the well organized transplant programs, all transplantation centers have access to the central computer database. In this important database, the transplantation centers enter information of their recipients along with the recipient profile and the donor profile. This is the basic principle of making the best match between donated organ and recipient. This p
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3

Leek, Rachael, Erika Aldag, Iram Nadeem, et al. "Scedosporiosis in a Combined Kidney and Liver Transplant Recipient: A Case Report of Possible Transmission from a Near-Drowning Donor." Case Reports in Transplantation 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/1879529.

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Scedosporium spp. are saprobic fungi that cause serious infections in immunocompromised hosts and in near-drowning victims. Solid organ transplant recipients are at increased risk of scedosporiosis as they require aggressive immunosuppression to prevent allograft rejection. We present a case of disseminated Scedosporium apiospermum infection occurring in the recipient of a combined kidney and liver transplantation whose organs were donated by a near-drowning victim and review the literature of scedosporiosis in solid organ transplantation.
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4

Sunjaya, Angela Felicia, and Anthony Paulo Sunjaya. "Combating Donor Organ Shortage: Organ Care System Prolonging Organ Storage Time and Improving the Outcome of Heart Transplantations." Cardiovascular Therapeutics 2019 (April 1, 2019): 1–7. http://dx.doi.org/10.1155/2019/9482797.

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Introduction. Cardiovascular diseases are the number one cause of death globally contributing to 37% of all global deaths. A common complication of cardiovascular disease is heart failure, where, in such cases, the only solution would be to conduct a heart transplant. Every 10 minutes a new patient is added to the transplant waiting list. However, a shortage of human donors and the short window of time available to find a correct match and transplant the donors’ heart to the recipient means that numerous challenges are faced by the patient even before the operation could be done, reducing thei
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5

Vinson, Amanda J., Prakash Chauhan, Christopher Daley, et al. "Successful Use of Kidneys from a Deceased Donor with Active Herpes Zoster Infection." Case Reports in Transplantation 2021 (August 16, 2021): 1–4. http://dx.doi.org/10.1155/2021/7719041.

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Background. The limited donor pool and increasing recipient wait list require a reevaluation of kidney organ suitability for transplantation. Use of higher infectious risk organs that were previously discarded may help improve access to transplantation and reduce patient mortality without placing patients at a higher risk of poor posttransplant outcomes. There is very little data available regarding the safe use of kidney organs from deceased donors with varicella zoster virus infection at the time of organ retrieval. Case Presentation. Here, we report a case of successful transplantation of b
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6

Aslam, Sadaf, Jacentha Buggs, Jacob Wasserman, et al. "Outcomes With Age Combinations in Living Donor Kidney Transplantation." American Surgeon 86, no. 6 (2020): 659–64. http://dx.doi.org/10.1177/0003134820923312.

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Introduction Reevaluation of donor criteria, including age, is needed to combat organ shortages, lengthy wait times, and anticipated recipient mortality rates. The purpose of this study was to evaluate donor and recipient (D/R) age combinations and patient and graft survival outcomes. Methods Single-organ, living donor kidney transplantations (LDKTs) from 2012 to 2018 were retrospectively reviewed. Donors and recipients were placed into “older” and “younger” age categories of 50 years and above or below age 50, then analyzed with SPSS version 25. Results We performed 347 LDKTs. Younger-to-olde
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7

Pouch, Stephanie M., Shalika B. Katugaha, Wun-Ju Shieh, et al. "Transmission of Eastern Equine Encephalitis Virus From an Organ Donor to 3 Transplant Recipients." Clinical Infectious Diseases 69, no. 3 (2018): 450–58. http://dx.doi.org/10.1093/cid/ciy923.

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Abstract Background In fall 2017, 3 solid organ transplant (SOT) recipients from a common donor developed encephalitis within 1 week of transplantation, prompting suspicion of transplant-transmitted infection. Eastern equine encephalitis virus (EEEV) infection was identified during testing of endomyocardial tissue from the heart recipient. Methods We reviewed medical records of the organ donor and transplant recipients and tested serum, whole blood, cerebrospinal fluid, and tissue from the donor and recipients for evidence of EEEV infection by multiple assays. We investigated blood transfusion
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8

Stine, Jonathan G., Neeral Shah, and Curtis Argo. "Immunosuppressed Solid Organ Transplant Recipient." Gastroenterology 146, no. 2 (2014): 345–590. http://dx.doi.org/10.1053/j.gastro.2013.09.045.

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9

Harel, Inbal, Tehila Kogut, Meir Pinchas, and Paul Slovic. "Effect of media presentations on willingness to commit to organ donation." Proceedings of the National Academy of Sciences 114, no. 20 (2017): 5159–64. http://dx.doi.org/10.1073/pnas.1703020114.

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We examine how presentations of organ donation cases in the media may affect people's willingness to sign organ donation commitment cards, donate the organs of a deceased relative, support the transition to an “opt-out” policy, or donate a kidney while alive. We found that providing identifying information about the prospective recipient (whose life was saved by the donation) increased the participants’ willingness to commit to organ donation themselves, donate the organs of a deceased relative, or support a transition to an “opt-out” policy. Conversely, identifying the deceased donor tended t
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10

Coleman-Musser, Lori, Kristine Nelson, and Roger Durand. "Discard Rates and Transplant Outcomes in Organs Recovered from Older Donors." Journal of Transplant Coordination 7, no. 4 (1997): 190–94. http://dx.doi.org/10.1177/090591999700700406.

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The number of donors aged 60 years and over has increased. This study examined discard rates and transplant outcomes in organs recovered from older donors. Data were obtained using a standard tool for donors aged 60 years and older during 1993 and 1994 and included demographics, medical history, use of vasopressors, renal/liver function studies, organ disposition, biopsy findings, and recipient organ function. Of 58 kidneys recovered, 24 were transplanted, 26 were used for research, and 8 were discarded. Of 14 livers recovered, 11 were transplanted, 1 was used for research, and 2 were discarde
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11

Said, Manal El. "Infections in the solid-organ transplant recipients." Ukrainian Journal of Nephrology and Dialysis, no. 2(70) (April 13, 2021): 64–76. http://dx.doi.org/10.31450/ukrjnd.2(70).2021.08.

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The advancement in the field of transplant has led to the increasing number of solid-organ transplant recipients (SOTRs). This success leads to novel confronts in communicable infections, which are compound by the emergence of newly contagious and antimicrobial drugs resistant microorganisms. The prevention of infections is a cornerstone of any modern solid organ transplantation program. Understanding the fundamentals of these infections with early detection is crucial for improving the outcomes of such patients and lowers the probable extra complications. The probability of critical infection
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12

Gregoire, J. R. "Immune hemolytic anemia after renal transplantation secondary to ABO-minor-mismatch between the donor and recipient." Journal of the American Society of Nephrology 4, no. 5 (1993): 1122–26. http://dx.doi.org/10.1681/asn.v451122.

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A 52-yr-old man developed immune hemolytic anemia approximately 2 wk after receiving an ABO-minor-mismatch renal transplant. When a Group O organ is transplanted into a non-O recipient or a non-AB organ is transplanted into a Group AB recipient, hemolysis can occur and has been attributed to a form of graft-versus-host disease in which donor plasma cells carried along with the graft produce red blood cell antibodies. In this case, the diagnosis was confirmed when an antibody screen indicated that the organ recipient's serum agglutinated panel red blood cells of the recipient's ABO group. This
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13

Pfundstein, Joann. "Aspergillus Infections among Solid Organ Transplant Recipients: A Case Study." Journal of Transplant Coordination 7, no. 4 (1997): 187–89. http://dx.doi.org/10.1177/090591999700700405.

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Infection remains a major cause of morbidity and mortality among transplant recipients. Aspergillus infections in particular are associated with a high mortality rate. The diagnosis of Aspergillus among transplant recipients may be difficult, because many patients have multiple complications. This article presents a case of Aspergillus in a heart transplant recipient. The discussion provides an overview of the presentation, diagnosis, and treatment of Aspergillus infections.
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14

Sonmez, Yusuf Ercin. "Future of Solid Organ Transplantation: Organ-Specific Tolerance." KIDNEYS 10, no. 3 (2021): 130–36. http://dx.doi.org/10.22141/2307-1257.10.3.2021.239589.

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A transplant between two people who are not genetically identical is called an allotransplant and the process is called allotransplantation. Donor organs and tissues can be from people who are living, or people who have died because of a significant brain injury or lack of circulation. Allotransplantation can create a rejection process where the immune system of the recipient attacks the foreign donor organ or tissue and destroys it. The recipient may need to take immunosuppressive medication for the rest of their life to reduce the risk of rejection of the donated organ. In general, deliberat
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15

Gautier, S. V., A. O. Shevchenko, O. M. Tsirulnikova, et al. "COVID-19 in solid organ transplant recipients: initial report from national multicenter observational study «ROKKOR-recipient»." Russian Journal of Transplantology and Artificial Organs 22, no. 3 (2020): 8–17. http://dx.doi.org/10.15825/1995-1191-2020-3-8-17.

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We herein present our initial report from «ROKKOR-recipient», a national multicenter observational study. The prevalence, risk factors, clinical manifestations and outcomes of the novel coronavirus disease 2019 (COVID-19) in solid organ transplant recipients receiving immunosuppressive therapy were investigated. The study enrolled 251 COVID-19 patients (220 kidney recipients, 7 liver recipients, 1 liver-kidney recipient, and 23 heart recipients). The subjects came from 20 regions in Russia. The symptoms, clinical presentation, imaging and lab test results, therapy and outcomes of COVID-19 were
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16

Conlon, P. J., and S. R. Smith. "Transmission of cancer with cadaveric donor organs." Journal of the American Society of Nephrology 6, no. 1 (1995): 54–60. http://dx.doi.org/10.1681/asn.v6154.

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A case is presented in which each of the recipients of a pair of cadaveric kidneys developed metastatic carcinoma. One of the recipients died, and the other demonstrated involution of metastatic deposits after graft nephrectomy and withdrawal of immunosuppression. By the use of polymerase chain reaction of minisatellite regions of donor and recipient DNA, the donor origin of the tumor was conclusively demonstrated. Although a relatively uncommon complication of cadaveric renal transplantation, the transmission of cancer with cadaveric organs may become more frequent as older donors are accepte
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17

Sengupta, Bodhisatwa, Iftikhar Khan, Akram Saiaghi, et al. "En Bloc Transplantation of Horseshoe Kidney from Deceased Donor: An Unusual Transplantation Utilizing Kidneys with Congenital Fusion Abnormality." Case Reports in Transplantation 2021 (August 11, 2021): 1–4. http://dx.doi.org/10.1155/2021/2286831.

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Transplanting horseshoe kidneys is challenging and has higher complication rates due to the unusual anatomy of the vascular and urinary collecting systems. Most centers avoid using these kidneys for transplantation. However, if chosen carefully, these organs can be used successfully to reduce organ shortage. In this paper, we will describe the technique of procurement of horseshoe kidneys from cadaveric donors, back table preparation, and its successful implantation in a recipient. With good planning and skillful surgical techniques, horseshoe kidneys can be successfully transplanted in suitab
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18

Ağasəlim qızı Abdullayeva, Fidan. "ORQAN BANKININ YARADILMASININ ƏHƏMİYYƏTİ." SCIENTIFIC WORK 53, no. 04 (2020): 44–47. http://dx.doi.org/10.36719/aem/2007-2020/53/44-47.

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19

Savitch, Stephanie, Robin Gilmore, and Denetta L. Dowler. "An Investigation of the Psychological and Psychosocial Challenges Faced by Post-Transplant Organ Recipients." Journal of Applied Rehabilitation Counseling 34, no. 3 (2003): 3–9. http://dx.doi.org/10.1891/0047-2220.34.3.3.

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Organ transplantation offers to some terminally ill people the opportunity to have their lives extended with the gift of an organ(s). Following transplantation, the organ recipient is given extensive medical care, but the psychological, psychosocial, and occupational needs of the person are rarely addressed. This study identified and defined these emotional and occupational challenges and presents the current and prospective role of the Rehabilitation Counselor. Fifty-four organ transplant recipients completed a two-page questionnaire covering the post-transplant experience. Analysis of the re
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20

Alkhunaizi, Ahmed M., Ali M. Bazzi, Ali A. Rabaan, and Elwaleed A. Ahmed. "FusariumInfection in a Kidney Transplant Recipient Successfully Treated with Voriconazole." Case Reports in Infectious Diseases 2018 (August 7, 2018): 1–4. http://dx.doi.org/10.1155/2018/3128081.

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Fusariuminfections in solid-organ transplant recipients are rare and carry high mortality. We report a case of a kidney transplant recipient who developed infection withFusariumspecies. The patient received treatment with oral voriconazole for five months with good response.
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21

Kontoyiarmis, Dimitrios P., and Robert H. Rubin. "INFECTION IN THE ORGAN TRANSPLANT RECIPIENT." Infectious Disease Clinics of North America 9, no. 4 (1995): 811–22. http://dx.doi.org/10.1016/s0891-5520(20)30703-0.

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22

Nwabueze, Remigius N. "Proprietary interests in organs in limbo." Legal Studies 36, no. 2 (2016): 279–301. http://dx.doi.org/10.1111/lest.12108.

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A host of activities jeopardise the safety of an excised organ: an organ transported across local, regional, state or national boundaries could be damaged or lost in transit. A thief might snatch the organ from the possession of the transplant team; a transplant surgeon could use the organ for the treatment of their relative or patient, a celebrity or an influential political figure, instead of transplanting the organ into the properly selected and designated recipient. Also, the organ could be damaged maliciously by a third party. Furthermore, a live donor might change their mind after the or
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Bahr, Nathan C., Katherine Janssen, Joanne Billings, Gabriel Loor, and Jaime S. Green. "Respiratory Failure due to Possible Donor-DerivedSporothrix schenckiiInfection in a Lung Transplant Recipient." Case Reports in Infectious Diseases 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/925718.

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Background. De novo and donor-derived invasive fungal infections (IFIs) contribute to morbidity and mortality in solid organ transplant (SOT) recipients. Reporting of donor-derived IFIs (DDIFIs) to the Organ Procurement Transplant Network has been mandated since 2005. Prior to that time no systematic monitoring of DDIFIs occurred in the United States.Case Presentation. We report a case of primary graft dysfunction in a 49-year-old male lung transplant recipient with diffuse patchy bilateral infiltrates likely related to pulmonarySporothrix schenckiiinfection. The organism was isolated from a b
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Beal, Eliza W., Dmitry Tumin, Lanla F. Conteh, et al. "Impact of Recipient and Donor Obesity Match on the Outcomes of Liver Transplantation: All Matches Are Not Perfect." Journal of Transplantation 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/9709430.

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There is a paucity of literature examining recipient-donor obesity matching on liver transplantation outcomes. The United Network for Organ Sharing database was queried for first-time recipients of liver transplant whose age was ≥18 between January 2003 and September 2013. Outcomes including patient and graft survival at 30 days, 1 year, and 5 years and overall, liver retransplantation, and length of stay were compared between nonobese recipients receiving a graft from nonobese donors and obese recipient-obese donor, obese recipient-nonobese donor, and nonobese recipient-obese donor pairs. 51,
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Rosales, Brenda, James Hedley, Nicole De La Mata, et al. "Safety and Biovigilance in Organ Donation (SAFEBOD): Protocol for a Population-Based Cohort Study." JMIR Research Protocols 9, no. 10 (2020): e18282. http://dx.doi.org/10.2196/18282.

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Background Tension lies between the need to increase access to organ transplantation and the equally urgent need to prevent inadvertent transmission of infectious diseases or cancer from organ donors. Biovigilance, or the evaluation of potential donors, is often time-pressured and may be based on incomplete information. Objective The Safety and Biovigilance in Organ Donation (SAFEBOD) study aims to improve estimates of infection and cancer transmission risk and explore how real-time data access could support decision-making. Methods We will link existing donor referral, actual donor, recipient
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Atreya, Chloe E., Eric A. Collisson, Meyeon Park, et al. "Molecular Insights in Transmission of Cancer From an Organ Donor to Four Transplant Recipients." Journal of the National Comprehensive Cancer Network 18, no. 11 (2020): 1446–52. http://dx.doi.org/10.6004/jnccn.2020.7622.

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Organ donors are systematically screened for infection, whereas screening for malignancy is less rigorous. The true incidence of donor-transmitted malignancies is unknown due to a lack of universal tumor testing in the posttransplant setting. Donor-transmitted malignancy may occur even when not suspected based on donor or recipient factors, including age and time to cancer diagnosis. We describe the detection of a gastrointestinal adenocarcinoma transmitted from a young donor to 4 transplant recipients. Multidimensional histopathologic and genomic profiling showed a CDH1 mutation and MET ampli
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Spallone, Amy, and Marion Hemmersbach-Miller. "The Great Masquerade: Donor-derived Infections with Uncommon Central Nervous System Pathogens." OBM Transplantation 05, no. 02 (2021): 1. http://dx.doi.org/10.21926/obm.transplant.2102141.

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Donor-derived infections (DDI) are an infrequent event in solid organ transplant (SOT) due to advances in screening recommendations, prophylaxis, and surveillance of common infections. However, unexpected pathogen transmission can still occur when a donor is not known to be infected prior to organ procurement, which can lead to significant morbidity and mortality in the organ recipient. Solid organ donors with central nervous system (CNS) pathogens are an uncommon but deadly source of unexpected DDI. Clinically recognizing these CNS infections in a potential deceased donor is enormously challe
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Flattery, Maureen P. "Incidence and Treatment of Cancer in Transplant Recipients." Journal of Transplant Coordination 8, no. 2 (1998): 105–12. http://dx.doi.org/10.1177/090591999800800209.

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Solid organ transplantation has been an accepted mode of therapy for the treatment of end-stage organ diseases for many years. Recipients' survival, however, has been hindered by organ rejection and the comorbid diseases that develop as a result of immunosuppressive therapy. In particular, organ transplant recipients have an increased risk of developing cancer de novo after transplantation. Prevalence ranges from 4 to 18% with an average incidence of 6%. Data submitted to the Cincinnati transplant tumor registry have revealed that cancers prevalent in the general population exhibited no increa
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Scarritt, Michelle E., and Stephen F. Badylak. "Organ engineering: promise, progress and perspective." Biochemist 38, no. 4 (2016): 20–23. http://dx.doi.org/10.1042/bio03804020.

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The only curative treatment option for patients with end-stage organ failure is transplantation. Organ engineering offers an alternative to traditional transplantation that may address the critical shortage of donor organs and eliminate the need for recipient immunosuppression. Organ engineering may be accomplished through the use of scaffold – support structures that contain the architecture of an organ. As organs are exceedingly complex, creating an organ scaffold is a difficult task; however, organ scaffolds can be derived through a process known as decellularization, which is the mechanica
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Grossi, Paolo Antonio. "Urban Spread of Flaviviruses: A New Challenge in Solid-organ Transplant Recipients." Clinical Infectious Diseases 70, no. 1 (2019): 149–51. http://dx.doi.org/10.1093/cid/ciz390.

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Abstract Yellow fever has never previously been reported in transplant recipients. The first reported case of yellow fever in a kidney transplant recipient in Brazil and the re-emergence of arboviruses in many areas of the world dictate the need of studies aimed to answer multiple unanswered questions.
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Vajentic, AnnaKay. "Correspondence and Personal Contact between Donor Families and Organ Recipients: One OPO's Procedure and Experience." Journal of Transplant Coordination 7, no. 3 (1997): 106–10. http://dx.doi.org/10.1177/090591999700700304.

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This article discusses one organ procurement organization's procedure for facilitating correspondence between donor families and recipients while respecting the needs and rights of all involved. From 1992 to 1995, a total of 542 donor family and recipient correspondences were facilitated. Recipients wrote more than 80% of the letters, with the number of donor family correspondence increasing each year. Trends are discussed including the percentage of correspondence initiated by donor families and recipients, reasons for correspondence not being forwarded by the organ procurement organization,
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Yadav, Anitha D., Yu-Hui Chang, Bashar A. Aqel, et al. "New Onset Diabetes Mellitus in Living Donor versus Deceased Donor Liver Transplant Recipients: Analysis of the UNOS/OPTN Database." Journal of Transplantation 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/269096.

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New onset diabetes after transplantation (NODAT) occurs less frequently in living donor liver transplant (LDLT) recipients than in deceased donor liver transplant (DDLT) recipients. The aim of this study was to compare the incidence and predictive factors for NODAT in LDLT versus DDLT recipients. The Organ Procurement and Transplant Network/United Network for Organ Sharing database was reviewed from 2004 to 2010, and 902 LDLT and 19,582 DDLT nondiabetic recipients were included. The overall incidence of NODAT was 12.2% at 1 year after liver transplantation. At 1, 3, and 5 years after transplan
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Wiltshire, Gareth, Nicola J. Clarke, Cassandra Phoenix, and Carl Bescoby. "Organ Transplant Recipients’ Experiences of Physical Activity: Health, Self-Care, and Transliminality." Qualitative Health Research 31, no. 2 (2020): 385–98. http://dx.doi.org/10.1177/1049732320967915.

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Physical activity (PA) is an important lifestyle component of long-term health management for organ transplant recipients, yet little is known about recipients’ experiences of PA. The purpose of this study was to shed light on this experience and to investigate the possible implications of PA in the context of what is a complex patient journey. Phenomenological analysis was used to examine interviews with 13 organ transplant recipients who had taken part in sporting opportunities posttransplantation. Findings illuminate how participants’ experiences of PA were commonly shaped by the translimin
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Goh, Su Kah, Vijayaragavan Muralidharan, Christopher Christophi, Hongdo Do, and Alexander Dobrovic. "Probe-Free Digital PCR Quantitative Methodology to Measure Donor-Specific Cell-Free DNA after Solid-Organ Transplantation." Clinical Chemistry 63, no. 3 (2017): 742–50. http://dx.doi.org/10.1373/clinchem.2016.264838.

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Abstract BACKGROUND Donor-specific cell-free DNA (dscfDNA) is increasingly being considered as a noninvasive biomarker to monitor graft health and diagnose graft rejection after solid-organ transplantation. However, current approaches used to measure dscfDNA can be costly and/or laborious. A probe-free droplet digital PCR (ddPCR) methodology using small deletion/insertion polymorphisms (DIPs) was developed to circumvent these limitations without compromising the quantification of dscfDNA. This method was called PHABRE-PCR (Primer to Hybridize across an Allelic BREakpoint-PCR). The strategic pl
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35

Ali, Mansur. "Our Bodies Belong to God, So What?" Journal of Arabic and Islamic Studies 19 (December 31, 2019): 57–80. http://dx.doi.org/10.5617/jais.7642.

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Organ transplantation is a morally challenging subject. It gives rise to several ethical dilemmas which question the very meaning of what it means to be a human being. For some Muslims, organ transplantation impinges on God’s claim to ownership. Research reveals that proponents of organ transplantation focus on the benefits afforded to the recipient, while opponents highlight the situation of the donor. For them the entire focus on the health benefits to the recipient turns a blind eye to the dignity of the donor who is viewed as nothing more than a repository for organs, to be extracted and t
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Chan, Kun-Ming, Chih-Hsien Cheng, Tsung-Han Wu, et al. "Impact of donor with evidence of bacterial infections on deceased donor liver transplantation: a retrospective observational cohort study in Taiwan." BMJ Open 9, no. 3 (2019): e023908. http://dx.doi.org/10.1136/bmjopen-2018-023908.

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ObjectiveThe shortage of available donor organs is an unsolvable concern leading to an expansion in the donor criteria for organ transplantation. Here, we describe our experience and assess the outcomes in recipients who obtained a graft from a donor with bacterial infections in deceased donor liver transplantation (DDLT).MethodsAll DDLTs between January 1991 and February 2017 were retrospectively reviewed. Patients were categorised into two groups based on the recipients who obtained a graft from a donor with (group I) or without (group II) evidence of bacterial infections. Outcomes and bacte
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Gingras, Marie-Claude, Aniko Sabo, Maria Cardenas, et al. "Sequencing of a central nervous system tumor demonstrates cancer transmission in an organ transplant." Life Science Alliance 4, no. 9 (2021): e202000941. http://dx.doi.org/10.26508/lsa.202000941.

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Four organ transplant recipients from an organ donor diagnosed with anaplastic pleomorphic xanthoastrocytoma developed fatal malignancies for which the origin could not be confirmed by standard methods. We identified the somatic mutational profiles of the neoplasms using next-generation sequencing technologies and tracked the relationship between the different samples. The data were consistent with the presence of an aggressive clonal entity in the donor and the subsequent proliferation of descendent tumors in each recipient. Deleterious mutations in BRAF, PIK3CA, SDHC, DDR2, and FANCD2, and a
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38

Zavascki, Alexandre Prehn, João Carlos Bienardt, and Luiz Carlos Severo. "Paracoccidioidomycosis in organ transplant recipient: case report." Revista do Instituto de Medicina Tropical de São Paulo 46, no. 5 (2004): 279–81. http://dx.doi.org/10.1590/s0036-46652004000500009.

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Paracoccidioidomycosis is a common disease in Latin America but it is rare in organ transplant recipient patients. We report on a case of such mycosis in a renal transplant recipient. The patient presented with a large lung cavity on the left lower lobe, a rare radiological presentation of paracoccidioidomycosis. Unusual clinical and radiological manifestations of Paracoccidioides brasiliensis infection can occur in immunocompromised patients.
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Nambiar, Puja H., Brianna Doby, Aaron A. R. Tobian, Dorry L. Segev, and Christine M. Durand. "Increasing the Donor Pool: Organ Transplantation from Donors with HIV to Recipients with HIV." Annual Review of Medicine 72, no. 1 (2021): 107–18. http://dx.doi.org/10.1146/annurev-med-060419-122327.

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Implementation of the HIV Organ Policy Equity (HOPE) Act marks a new era in transplantation, allowing organ transplantation from HIV+ donors to HIV+ recipients (HIV D+/R+ transplantation). In this review, we discuss major milestones in HIV and transplantation which paved the way for this landmark policy change, including excellent outcomes in HIV D–/R+ recipient transplantation and success in the South African experience of HIV D+/R+ deceased donor kidney transplantation. Under the HOPE Act, from March 2016 to December 2018, there were 56 deceased donors, and 102 organs were transplanted (71 k
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Gassa, Asmae, Fu Jian, Halime Kalkavan, et al. "IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts." Cellular Physiology and Biochemistry 38, no. 3 (2016): 1171–81. http://dx.doi.org/10.1159/000443067.

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Background/Aims: Unexpected transmissions of viral pathogens during solid organ transplantation (SOT) can result in severe, life-threatening diseases in transplant recipients. Immune activation contributes to disease onset. However mechanisms balancing the immune response against transmitted viral infection through organ transplantation remain unknown. Methods & Results: Here we found, using lymphocytic choriomeningitis virus (LCMV), that transplantation of LCMV infected hearts led to exhaustion of virus specific CD8+ T cells, viral persistence in organs and survival of graft and recipient
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Sheikhalipour, Zahra, Vahid Zamanzadeh, Leili Borimnejad, Sarah E. Newton, and Leila Valizadeh. "Muslim transplant recipients’ family experiences following organ transplantation." Journal of Research in Nursing 24, no. 5 (2019): 291–302. http://dx.doi.org/10.1177/1744987118813671.

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Background Despite the importance of family and its relationship to positive transplant outcomes, little is known about family experiences following organ transplantation from the perspective of the transplant recipients. The literature is also devoid of information that describes the family experiences of Muslim transplant recipients. Aims The purpose of this study was to describe Muslim transplant recipients’ family experiences following organ transplantation. Methods A hermeneutical phenomenological approach was employed to determine the emergent themes present in the data. The sample was c
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Chiang, Scott, Minh Chau Vu, Mychelle Nguyen, Ali Strocker, Stefan Horvath, and Nina Shapiro. "Adenotonsillar Enlargement in Pediatric Organ Transplant Recipients: A Cross-Sectional Analysis." Otolaryngology–Head and Neck Surgery 127, no. 1 (2002): 109–14. http://dx.doi.org/10.1067/mhn.2002.126476.

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OBJECTIVE: Our goal was to statistically correlate adenotonsillar hypertrophy (ATH) in the pediatric posttransplant population with potential risk factors and to monitor the progression of ATH over time. STUDY DESIGN AND SETTING: Participants were evaluated for ATH through a standardized 65-point questionnaire and an 8-point physical examination. They were also evaluated for current age, age at time of transplantation, type of organ transplant, gender, tacrolimus use, history of transplant rejection, Epstein-Barr virus (EBV) serology, and cytomegalovirus (CMV) serology. We evaluated 243 pediat
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Sester, Martina, Barbara C. Gärtner, Matthias Girndt, and Urban Sester. "Vaccination of the solid organ transplant recipient." Transplantation Reviews 22, no. 4 (2008): 274–84. http://dx.doi.org/10.1016/j.trre.2008.07.001.

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Cuellar, David C., and Geoffrey N. Sklar. "Penile prosthesis in the organ transplant recipient." Urology 57, no. 1 (2001): 138–41. http://dx.doi.org/10.1016/s0090-4295(00)00876-1.

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Fox, Mark D. "When an Organ Donor Names the Recipient." American Journal of Nursing 96, no. 7 (1996): 66. http://dx.doi.org/10.1097/00000446-199607000-00051.

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Avery, Robin K. "Fungal infections in the organ transplant recipient." Current Opinion in Organ Transplantation 6, no. 4 (2001): 284–89. http://dx.doi.org/10.1097/00075200-200112000-00002.

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Mateo, Rod, Mark L. Barr, Robert Selby, Linda Sher, Nicolas Jabbour, and Yuri Genyk. "Donor organ preservation effects on the recipient." Current Opinion in Organ Transplantation 7, no. 1 (2002): 53–59. http://dx.doi.org/10.1097/00075200-200203000-00012.

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Avery, Robin K. "Recipient Screening Prior to Solid‐Organ Transplantation." Clinical Infectious Diseases 35, no. 12 (2002): 1513–19. http://dx.doi.org/10.1086/344777.

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Şensoy, Gülnar, and Nurşen Belet. "InvasiveCandidainfections in solid organ transplant recipient children." Expert Review of Anti-infective Therapy 9, no. 3 (2011): 317–24. http://dx.doi.org/10.1586/eri.11.6.

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Ueda, Yoshihide, and Tsutomu Chiba. "Helicobacter pylori in solid-organ transplant recipient." Current Opinion in Organ Transplantation 13, no. 6 (2008): 586–91. http://dx.doi.org/10.1097/mot.0b013e3283186b6a.

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