Academic literature on the topic 'Organochlorine pesticides (OCs)'

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Journal articles on the topic "Organochlorine pesticides (OCs)"

1

Eldakroory, SA, DA El Morsi, RH Abdel-Rahman, S. Roshdy, MS Gouida, and EO Khashaba. "Correlation between toxic organochlorine pesticides and breast cancer." Human & Experimental Toxicology 36, no. 12 (2017): 1326–34. http://dx.doi.org/10.1177/0960327116685887.

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Organochlorines (OCs) are common environmental pollutants that have been linked to cancer. This work aims to assess the role of OCs as a risk factor for breast cancer and to evaluate the cellular changes induced by exposure to such environmental contaminants. The study included 70 cancer patients subjected to thorough history taking and routine investigations. Samples from tumor and normal adjacent tissue were taken to measure OCs’ levels and to perform molecular analysis (some oncogenic and apoptotic markers) by flow cytometry. There were significantly higher concentrations of methoxychlor, dichloro-diphenyl-trichloroethane (DDT), hexa-chlorobenzene (HCB), and chlordane in tumor tissue samples compared to the surrounding normal tissue. There was a positive statistically significant correlation between G2m and dichloro-diphenyl-dichloroethane, DDT, and methoxychlor. There was also a negative correlation between propidium iodide (PI) and heptachlor as well as between PI, B-cell lymphoma 2, and methoxychlor. Annexin showed a negative correlation with HCB and methoxychlor. In conclusion, the higher level of organochlorine pesticides in the tissue specimens of breast cancer and the resultant molecular dysfunction highlight a possible association. Further research is warranted to elucidate the other possible mechanisms involved in the process of carcinogenesis.
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Inomata, Odete N. K., R. C. Montone, W. H. Lara, R. R. Weber, and H. H. B. Toledo. "Tissue distribution of organochlorine residues – PCBs and pesticides – in Antarctic penguins." Antarctic Science 8, no. 3 (1996): 253–55. http://dx.doi.org/10.1017/s0954102096000351.

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Antarctic penguins constitute excellent indicators of organic pollutants (PCBs, DDTs and HCHs), which reach the Antarctic either by atmospheric or maritime transport and are concentrated through the food chains. They are found mainly in lipids, both in adipose and other tissues of the organisms. Tissue samples of four gentoo and one Adélie penguins were collected during the summers of 1991, 1992 and 1993. PCBs and organochlorine pesticides (OCPs) were analysed in the adipose tissue, uropygeal gland, blood, brain, muscle, bone and liver. Organochlorines (OCs) were detected in the majority of the samples. The levels found in extractable fat were higher than in other tissues and the concentrations ranged from 42.3–1159.7 ng g−1 (HCB), from not detected to 39.3 ng g−1 (HCHs), from 30.8–972.3 ng g−1 (DDTs) and from 43.2–1583.6 ng g−1 (PCBs).
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3

Park, Jae-Woo, A. M. Abd El-Aty, Myoung-Heon Lee, Sung-Ok Song, and Jae-Han Shim. "Residue Analysis of Organophosphorus and Organochlorine Pesticides in Fatty Matrices by Gas Chromatography Coupled with Electron-Capture Detection." Zeitschrift für Naturforschung C 61, no. 5-6 (2006): 341–46. http://dx.doi.org/10.1515/znc-2006-5-607.

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A multiresidue method for the simultaneous determination of 22 organochlorine (OCs) and organophosphorus (Ops) pesticides (including isomers and metabolites), representing a wide range of physicochemical properties, was developed in fatty matrices extracted from meat. Pesticides were extracted from samples with acetonitrile/n-hexane (v :v, 1:1). The analytical screening was performed by gas chromatography coupled with electron-capture detection (ECD). The identification of compounds was based on their retention time and on comparison of the primary and secondary ions. The optimized method was validated by determining accuracy (recovery percentages), precision (repeatability and reproducibility), and sensitivity (detection and quantitation limits) from analyses of samples fortified at 38 to 300 ng/g levels. Correlation coefficients for the 22 extracted pesticide standard curves (linear regression analysis, n = 3) ranged from 0.998 to 1.000. Recovery studies from 2 g samples fortified at 3 levels demonstrated that the GC-ECD method provides 64.4-96.0% recovery for all pesticides except 2,4′-DDE (44.6-50.4%), 4,4′-DDE (51.1-57.5%) and 2,4′-DDT (50.0-51.2%). Both repeatability and reproducibility relative standard deviation values were < 20% for all residues. Detection limits ranged from 0.31 to 1.27 ng/g and quantification limits were between 1.04 and 4.25 ng/g. The proposed analytical method may be used as a simple procedure in routine determinations of OCs and Ops in meat. It can also be applied to the determination of pesticide multi-residues in other animal products such as butter and milk.
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Chanti-Ketterl, Marianne, Maria Aranda, and Brenda Plassman. "ORGANOCHLORINE EXPOSURES AND COGNITIVE FUNCTION IN OLDER LIFE: THE ROLE OF RACE/ETHNICITY." Innovation in Aging 6, Supplement_1 (2022): 341–42. http://dx.doi.org/10.1093/geroni/igac059.1351.

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Abstract Organochlorines (OCs) are persistent pesticides that remain in the environment and body for extended periods after exposure. Little is known about their long-term impact on cognition in later life. Some studies, but not all, have shown that higher levels of selected OCs are associated with lower cognitive function (CF). Using weighted linear generalized estimating equations, we explored whether the association between lipid-adjusted levels of 8 OCs and global CF is modified by race/ethnicity in 985 adults age 60+ from the National Health and Nutrition Examination Surveys (2011-2014). Adjusting for covariates, results indicated that higher levels of grouped-OCs are not associated with lower CF (p=0.121), but higher levels of specific OCs were associated with lower CF: Mirex[p=0.029]; Oxychlordane[p=0.036]; p,p’-DDE[p=0.009]; p,p’-DDT[p=0.003]; and trans-Nonachlor[p=0.023]. These associations did not differ by race/ethnicity. Disentangling the complex impact of OCs on late-life cognition—whether in combination or singularly—may lead to more equitable environmental health policies.
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5

Malakhova, L. V., E. N. Skuratovskaya, T. V. Malakhova, A. R. Boltachev, and V. V. Lobkо. "Organochlorine compounds in scorpion fish Scorpaena porcus Linnaeus, 1758 in the Sevastopol marine area (Black Sea): spatial distribution and biological response." Marine Biological Journal 3, no. 4 (2018): 51–63. http://dx.doi.org/10.21072/mbj.2018.03.4.06.

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Despite the ban on the use of organochlorine compounds (OCs), they are still widely distributed in various components of the Black Sea ecosystem, including fish. Sevastopol marine area, as a region of active economic use, is a subject of significant anthropogenic impact. The levels of OCs contamination in the scorpion fish Scorpaena porcus Linnaeus, 1758, which leads a sedentary life, can serve as an indicator of such impact. The organochlorine compounds were determined in 58 samples of white muscles, gonads and liver of the scorpion fish captured in 2016–2017 in the various bays of Sevastopol (Aleksandrovskaya, Balaklava, Kazach’ya, Streletskaya, Laspi), as well as in the open coastal water area (the area of the Lyubimovka village). The qualitative and quantitative analyses of organochlorine pesticides and six indicator congeners of polychlorinated biphenyls were performed by gas chromatography with a micro-electron capture detector. To determine the response of scorpion fish to the contamination level, such biochemical markers, as alanine aminotransferase, aspartate aminotransferase, catalase activities, albumin content, level of oxidative protein modification and malondialdehyde concentration, were studied in the liver of fish from these areas. The OCs content in fish depended on the contamination of the fish habitat. The highest OCs level is in fish organs from bays (Alexandrovskaya, Streletskaya, Balaklava), and the smallest – in the fish organs from open Laspi Bay. The accumulation of OCs in the scorpion fish organs differed according to the lipid content in their tissues. The maximum rates of OCs concentrations were in the liver of fish catch from all investigated regions, the minimum – in the gonads (from bays samples) and in the white muscles (from open areas samples). The obtained relationships between the OCs content and biochemical parameters indicate the weakening of antioxidant protection and the increasing of oxidative stress in fish as a result of the xenobiotic accumulation.
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6

Helmy, Manar A., Amal Saad-Hussein, Heba Allah Abd El Rahman, et al. "Association between toxic organochlorine levels in human serum and systemic lupus erythematosus." Lupus 30, no. 14 (2021): 2204–12. http://dx.doi.org/10.1177/09612033211051947.

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Organochlorines (OCs) are groups of highly toxic pesticides with known immunotoxicity. The present work aimed to study the potential association between serum residues of OCs and the risk of developing systemic lupus erythematosus (SLE) as well as correlating to the clinical-laboratory manifestations in a sample of Egyptian SLE patients. A cross-sectional study was conducted on 132 patients environmentally exposed to OCs. Patients were diagnosed as SLE based on the American College of Rheumatology (ACR) revised criteria. Systemic Lupus Erythematosus Disease Activity Index-2000 (SLEDAI-2K) score was calculated to stratify the disease severity. Blood and urine samples were collected to measure the levels of OCs, serological markers, and urinary protein. The most frequently detected OCs were p,p’-DDE; lindane; and hexachlorobenzene (HCB). The risk of developing SLE was significantly associated with detected p,p’-DDE and HCB (B value 7.704 and 14.33, respectively). Hexachlorobenzene, in addition, was significantly associated with increased SLEDAI-2K score and polycythemia. Lindane was significantly associated with hypocomplementemia, cardiac manifestations of SLE, anemia, and leucopenia. In conclusion, the detected OCs p,p’-DDE and HCB are associated with increased risk of SLE in Egyptian patients and correlates to the manifestations of disease severity.
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7

Pakade, Yogesh B., Vanita Chahal, Navdeep Singh, Avinash Nagpal, and Jatinder K. Katnoria. "Monitoring of Pesticides Level in Agricultural Soils using Validated Method." INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT 5, no. 01 (2019): 33–39. http://dx.doi.org/10.18811/ijpen.v5i01.6.

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Agricultural soil serves as a natural medium for the growth of a variety of edible crops and vegetables. Likewise, systematic assessment of agricultural soil becomes mandatory as it reflects direct linkage with the food chain and health of living beings. In the past few decades, it has been detected with the presence of various environmental contaminants being heavy metals and pesticides. The current research focuses on the investigation of different pesticides viz., organophosphorous (OPPs) and organochlorine (OCs) in agricultural soils of Amritsar (India) using gas chromatograph. All soil samples (except south zone) were found to be contaminated with one or the other pesticide. The linearity was observed over the range from 0.1 to 1.0 mg L-1 for all pesticides. The coefficient of determination (r2) was observed in the range of 0.916 to 0.999. The LODs, based on signal-to-noise (S/N) ratio of 3, ranged from 0.003 to 0.009 mg L-1. The precision of the proposed method was presented and accepted with an RSD greater than 20%. This report pertains to the presence of alarming concentrations of pesticides in soils of Amritsar (India).
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8

Parolini, Marco, Sara Panseri, Federico Håland Gaeta, et al. "Legacy and Emerging Contaminants in Demersal Fish Species from Southern Norway and Implications for Food Safety." Foods 9, no. 8 (2020): 1108. http://dx.doi.org/10.3390/foods9081108.

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The present study aimed at measuring the levels of legacy and emerging contaminants in fillet samples from four demersal fish caught in two fishing sites from Southern Norway, in order to assess possible implications for food safety. Levels of organochlorine compounds (OCs), organophosphate pesticides (OPs), polychlorinated biphenyls (PCBs), polybromodiphenyl ethers (PBDE), per- and polyfluoroalkyl substances (PFASs), and polycyclic aromatic hydrocarbons (PAHs) were measured in fillet from Atlantic cod (Gadus morhua), European plaice (Pleuronectes platessa), lemon sole (Microstomus kitt), and European flounder (Platichthys flesus) specimens. A negligible contamination by all the investigated chemicals was noted in both the fishing sites, as very low levels of OCs, PCBs, and PFASs were noted in a limited number of individuals for each species. Considering the levels of contaminants measured in fillets of the four demersal fish species, negligible risk for human health for Norwegian consumers can be supposed.
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9

Massone, Carlos German, Allan Amendola dos Santos, Pedro Gonçalves Ferreira, and Renato da Silva Carreira. "Persistent Organic Pollutants (POPs) in Sardine (Sardinella brasiliensis): Biomonitoring and Potential Human Health Effects." International Journal of Environmental Research and Public Health 20, no. 3 (2023): 2036. http://dx.doi.org/10.3390/ijerph20032036.

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Organochloride (OC) and polychlorinated biphenyl (PCB) concentrations were determined in the muscle tissue of fifty sardine samples (Sardinella brasiliensis) sampled off the south-east Brazilian shelf. The aim herein was to investigate OCs and PCBs composition profile, bioaccumulation potential and human risks. The concentrations of 18 organochlorine pesticides (OCPs) were below the method limit of quantification in most samples (ca. 94%), with few detected, namely δ-HCH, γ-HCH, Endosulfan I and II, Endosulfan Sulphate, DDE, Dieldrin, Endrin, Endrin Aldeide, Endrin Cetone and Metoxyclor. The median concentration for the Σ41 PCBs was 2.32 ng g−1 , ranging from values below the limit of quantification (<LOQ) to 37.2 ng g−1. Based on the analyzed samples, the concentrations reported herein do not represent a risk for human consumption according to both national and international guidelines, nor do OC and PCB bioaccumulation in sardines appear to be a concern at the moment. These findings, although preliminary, represent a baseline for future comparisons of the quality of an important source of protein available to the poorest Brazilian population strata.
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10

Garcia-Hernandez, J., D. Aguilera-Marquez, F. Sofia-Cital, G. Leyva-Garcia, J. Ramirez-Hernandez, and E. P. Glenn. "Removal of organochlorine pesticides (OCs) using constructed wetlands in a northwestern Mexican agricultural valley." Toxicology Letters 259 (October 2016): S96. http://dx.doi.org/10.1016/j.toxlet.2016.07.241.

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