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Dissertations / Theses on the topic 'Organosulfur Amino Acid Derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Peters, Steven Carlton. "Crosslinked amino acid derivatives." Title page, table of contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09php4831.pdf.

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2

Van, Kralingen Leon. "Controlled polymerization of amino acid derivatives." Thesis, Link to the Internet, 2008. https://etd.sun.ac.za/jspui/handle/10019/919.

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3

Kociuba, Katherine. "Radical functionalisation of amino acid derivatives /." Title page, table of contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09phk76.pdf.

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4

Tan, Eng Wui. "Regioselective modification of amino acid derivatives /." Title page, contents and abstract only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09pht1612.pdf.

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5

Goubet, D. C. M. "Asymmetric synthesis of α-amino acid derivatives". Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637081.

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A general background to α-amino acids is discussed in the first chapter. After a brief account on classification, properties and applications of these compounds, asymmetric processes leading to optically enriched residues are reviewed in detail. The second chapter describes the envisaged stereoselective approach towards these substrates involving Michael-type addition onto a chiral didehydroalanine derivative. Syntheses of α,β-unsaturated amino acids are reviewed after a brief section on Michael-type reactions. The preparation of a chiral didehydroamino acid residue has been investigated using

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6

Hay, M. P. "Atom transfer reactions of amino acid derivatives." Thesis, University of Canterbury. Chemistry, 1987. http://hdl.handle.net/10092/7974.

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Investigations of atom transfer reactions of amino acid derivatives are described in this thesis. Reaction of N-benzoylvaline methyl ester (29a) with sulphuryl chloride gave the β-chlorovaline derivative (30a) and lesser amounts of diastereoisomers of the r-chlorovaline derivative (31a). Studies of reactions of the valine derivatives (29a-c) with sulphuryl chloride, and of the photolyses of the corresponding N-chlorovaline derivatives (39a-c) have shown that the reaction of (29a) with sulphuryl chloride and the photolysis of (39a) involve regioselective intermolecular transfer of the respectiv

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7

Masesane, Ishmael Baperi. "Stereoselective routes to cyclic β-amino acid derivatives". Thesis, Durham University, 2003. http://etheses.dur.ac.uk/3700/.

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The literature structure of the natural product oryzoxymycin and an array of 3-mono-,3,4-di- and 3,4,5-tri-hydroxylated derivatives of 2-aminocyclohexane-l-carboxyhc acid (ACHC) were stereoselectively prepared from oxanorbomene adducts derived from the Diels Alder reaction of ethyl (E)-3-nitroacrylate and furan. The central reaction for these syntheses was the base mediated β-elimination of the oxygen bridge of the oxanorbomene adducts or their derivatives. The asymmetnc synthesis of the literature structure of oryzoxymycin involved chiral HPLC or enzyme catalysed kinetic resolution of the end

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8

Smith, David John. "Complexation of amino-acid derivatives using macrocyclic receptors." Thesis, University of Bath, 1996. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319219.

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9

Ng, S. C. "Enzymatic and non enzymatic synthesis of amino acid derivatives." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379948.

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10

Kausar, Nighat. "Experimental spectroscopic and theoretical studies of amino acid derivatives." Thesis, University of Greenwich, 2008. http://gala.gre.ac.uk/6207/.

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Experimental vibrational/electronic circular dichroism spectroscopic and theoretical studies of amino acid derivatives, i.e. N-acetyl-L-Asp, N-acetyl-L-Glu, and di-amino acid peptide/derivatives, i.e. L-Asp-L-Glu, a-N-acetyl-L-Asp-L-Glu, and ß-N-acetyl-L-Asp-L-Glu are reported. The calculated structures for N-acetyl-L-Asp and N-acetyl-L-Glu differ. The conformation of the trans amide moiety changes with the carbon chain length of the side chain of the amino acid derivatives. In the computed structures of N-acetyl-L-Asp and N-acetyl-L-Glu all backbone atoms are in-plane, except the side chain g

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11

Shepherd, Emma J. "The development of enantioselective receptors for amino acid derivatives." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343011.

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12

Mas-Roselló, Josep. "C-arylation and alkenylation of α-amino acid derivatives". Thesis, University of Bristol, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738542.

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13

Leung, Wai-yin David. "Synthesis and physical properties of fatty acid derivatives containing amino, amido functions and L-amino acid residues /." [Hong Kong : University of Hong Kong], 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13637666.

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14

Mahajan, Anju. "Chemistry of 4-azalysine and its derivatives." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324756.

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15

Wang, Yulan. "Spectroscopic studies of solid amino acid derivatives and their mixtures." Thesis, University of East Anglia, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389201.

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16

Evans, Lyndsay Ann. "Synthesis of hydroxy and amino acid derivatives using stereoselective epoxidation." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425618.

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17

Garrido, Neil. "The asymmetric synthesis of Î±- and Î²-amino acid derivatives." Thesis, University of Reading, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428296.

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18

Withell, Kirsti. "Gas-phase pyrolysis of amino- and amidomethylidene Meldrum's acid derivatives." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/11597.

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A range of new amino- and amidomethylidene Meldrum's acid derivatives have been prepared and subjected to flash vacuum pyrolysis. The <I>N-</I>substituents were chosen as potential groups for the expected pyrolysis products, pyrrol-3(2<I>H</I>)-ones. The initial use of silanes, hydrazines and benzylamines was not successful; silylamines were quantitatively deprotected on reaction with 5-methoxymethylidene Meldrum's acid (MMMA), hydrazine derivatives were successfully prepared but pyrolyses failed to produce protected pyrrolones and, although <I>N-</I>benzyl protected pyrrolones could be prepar

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19

Glink, Peter Thomas. "Synthesis of unsaturated [alpha]-amino acid derivatives by palladium catalysed modification /." Title page, contents and absract only, 1993. http://web4.library.adelaide.edu.au/theses/09PH/09phg561.pdf.

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20

Foley, Mark Kneale. "Characterisation of the interactions between amino acid derivatives and phenolic compounds." Thesis, Bangor University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443633.

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21

Brown, Stuart Andrew. "Dynamic kinetic resolution : synthesis of optically active α-amino acid derivatives". Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/13058.

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The dynamic kinetic resolution of 2-phenyl-4-subsittuted-5(4<I>H</I>)-oxazolones 89a-g has been investigated as a method for the synthesis of optically active α-amino acid derivatives. The effects of lipase, [either Novozyme (<I>Candida antarctica </I>lipase B), or Lipozyme (<I>Rhizomucor miehei</I> lipase)], solvent, nucleophile, and the addition of external triethylamine to the reaction is described. When R<SUP>1</SUP> = Ph, an 88% yield and 98% enantiomeric excess (e.e.) of α-amino acid ester 96a was obtained with Novozyme<SUP>®</SUP> in acetonitrile as solvent. The synthesis of novel 5(4<I

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22

Treweeke, Nigel R. "Preparation of #alpha#-substituted amino acid derivatives by dynamic kinetic resolution." Thesis, University of Sussex, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390818.

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23

Spray, Caroline Ann. "4-ketoproline derivatives as chiral templates in synthesis." Thesis, University of Sussex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239542.

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(2S)-trans-4-Hydroxyproline has been studied as a chiral template for the preparation of kainoids. Conversion to protected 4-ketoproline derivatives has allowed functionalisation at C-3 to be investigated. Although the tendency to epimerisation has caused problems, we have successfully introduced a variety of alkyl side chains with cis stereochemistry at this position. Functionalisation of the 3-alkyl-4-ketoprolines at C-4 has been investigated and a method has been found to prepare compounds which are functionalised stereospecifically at both C-3 and C-4. These have potential for study as kai

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24

梁偉賢 and Wai-yin David Leung. "Synthesis and physical properties of fatty acid derivatives containingamino, amido functions and L-amino acid residues." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1993. http://hub.hku.hk/bib/B31233752.

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25

Laughton, Peter. "Synthesis of #beta#-carboxyaspartic acid derivatives and studies on 3-methoxycarbonylmethylene-3,4,5,6-tetrahydro- 2H-1,4-oxazine-2-one derivatives." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390088.

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26

Vogt, Henning. "Organo catalytic strategies towards [alpha], [alpha] [alpha, alpha] disubstituted amino acid derivatives." Berlin Logos-Verl, 2006. http://deposit.d-nb.de/cgi-bin/dokserv?id=2861590&prov=M&dok_var=1&dok_ext=htm.

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27

Pim, Huat Phua. "Asymmetric aza-Michael reactions for the synthesis of Î²-amino acid derivatives." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441296.

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28

Jiang, Rong. "Benzotriazole auxiliary in the synthesis of heterocyclic compounds and amino acid derivatives." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0011594.

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29

Fratpietro, Stephen W. "Structural determinations by analytical analysis of 7-phosphanorbornadiene derivatives and amino acid enantiomers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ60842.pdf.

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30

Szeki, Andrea. "Stereoselective synthesis of #alpha#-hydroxy-#beta#-amino and #alpha#,#beta#-diamino acid derivatives." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285938.

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31

Burgaud, Beatrice Ghyslaine Michele. "Chiral synthesis of novel amino acid derivatives and their incorporation into cholecystokinin ligands." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627522.

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32

Gundhla, Isaac Zvikomborero. "a pH-metric speciation and anti-diabetic study of oxovanadium (IV) amino acid derivatives." Thesis, Rhodes University, 2011. http://hdl.handle.net/10962/d1006691.

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Novel oxovanadium(IV) complexes of glycine, ʟ-alanine, 1-methylimidazole-2-carboxylic acid, imidazole-2-caboxylic acid and imidazole-4-carboxylic acid were synthesized and isolated in the solid state. The ligands and complexes were characterized by elemental analysis, melting point, NMR, IR and UV-vis spectroscopy. The IR studies showed that glycine and ʟ-alanine coordinate monodentately through the amine nitrogen whilst the imidazole-carboxylic acid derivatives assume a bidentate chelation. The electronic spectroscopic studies indicate distorted octahedral geometry for the oxovanadium complex

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33

Dudding, Travis C. "Methods for the catalytic enantioselective synthesis of [Alpha]-amino and [Beta]-aspartic acid derivatives." Available to US Hopkins community, 2002. http://wwwlib.umi.com/dissertations/dlnow/3080653.

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34

Kapur, Neha. "Radical approaches towards the synthesis of peptidomimetic templates." Thesis, University of York, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323502.

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35

Wenjie, Lu. "Synthesis and Evaluation of Functionalized Dirhodium(II) Carboxylate Catalysts Bearing Axially Chiral Amino Acid Derivatives." 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225528.

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36

Hawkins, Lynda Mary. "An investigation of non-NMDA glutamate receptors : using novel derivatives of the amino acid, willardiine." Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337290.

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37

Mistry, Mala. "Studies towards the synthesis of novel #alpha#-amino acid derivatives using dynamic kinetic resolution methods." Thesis, University of Sussex, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289229.

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38

Anbazhagan, M. "Reactions of lactim ethers, lactim thioethers and carbonimidodithioates: utilization for the synthesis of amino acid derivatives." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1998. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3402.

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39

Lasry, Philippe. "Asymmetric synthesis of amino acid derivatives as molecular probes for the mechanism of 3-methylaspsartate ammonia-lyase." Thesis, University of St Andrews, 1998. http://hdl.handle.net/10023/15430.

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3-Methylaspartate ammonia-lyase is a bacterial enzyme that catalyses the reversible elimination of ammonia, in the presence of monovalent and divalent metal ions, from (2S,3S)-3-methylaspartic acid to yield mesaconic acid. The catalytic mechanism of the wild type enzyme obtained from Clostridium tetanomorphum involves a concerted elimination of ammonia and is thought to operate via the intermediacy of a dehydroalanine residue at the active site. No direct evidence has been established so far concerning the existence of this dehydroalanine residue, except that 3-methylaspartate ammonia-lyase wa

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40

Ulivi, Paola <1975&gt. "Activity and mechanisms of action of novel organosulfur derivatives of the HDAC inhibitor Valproic Acid in human experimental models of non-small-cell lung cancer." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6310/1/Ulivi_Paola_tesi.pdf.

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Non-small-cell lung cancer (NSCLC) represents the leading cause of cancer death worldwide, and 5-year survival is about 16% for patients diagnosed with advanced lung cancer and about 70-90% when the disease is diagnosed and treated at earlier stages. Treatment of NSCLC is changed in the last years with the introduction of targeted agents, such as gefitinib and erlotinib, that have dramatically changed the natural history of NSCLC patients carrying specific mutations in the EGFR gene, or crizotinib, for patients with the EML4-ALK translocation. However, such patients represent only about 15-20

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41

Ulivi, Paola <1975&gt. "Activity and mechanisms of action of novel organosulfur derivatives of the HDAC inhibitor Valproic Acid in human experimental models of non-small-cell lung cancer." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6310/.

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Non-small-cell lung cancer (NSCLC) represents the leading cause of cancer death worldwide, and 5-year survival is about 16% for patients diagnosed with advanced lung cancer and about 70-90% when the disease is diagnosed and treated at earlier stages. Treatment of NSCLC is changed in the last years with the introduction of targeted agents, such as gefitinib and erlotinib, that have dramatically changed the natural history of NSCLC patients carrying specific mutations in the EGFR gene, or crizotinib, for patients with the EML4-ALK translocation. However, such patients represent only about 15-20

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42

Kinghorn, Michael James. "Bifunctional Helical Peptide Catalysts for Enzyme-like Reactivity and Selectivity and Selective Stapling of Natural Amino Acid Residues with Hydrophilic Squaric Acid Derivatives." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/8714.

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Peptide secondary structure provides an exceptional scaffold on which to design highly reactive and selective enzyme-like catalysts. This work describes the rational design and synthesis of a suite of helical peptide catalysts that are capable of achieving proximity-induced rate enhancement in Diels-Alder cycloadditions and indole alkylations. Microwave assisted synthesis of resin-supported polypeptides enables incorporation of non-natural amino acid residues that induce helicity (Aib) or provide functional handles on which organic catalytic residues can be attached. These small peptide cat

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43

Cox, Glen Adam. "Towards the Synthesis of N-Acetyl-2-amino-2-deoxy-D-mannopyranose uronic acid (D-ManNAcA) and Derivatives." Youngstown State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1217344144.

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44

Takeuchi, Mifune. "Practical synthesis of optically active α,α-disubstituted α-amino acid derivatives by phase-transfer-catalyzed asymmetric alkylation". 京都大学 (Kyoto University), 2005. http://hdl.handle.net/2433/145113.

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45

Olszewski, Tomasz Krzysztof. "Original syntheses of new biomolecules : from imidazole and thiazole derivatives of α-aminophosphonic acids and γ-amino-α, β-dihydroxy carboxylic acid derivatives to disaccharide mimics". Montpellier 2, 2006. http://www.theses.fr/2006MON20017.

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46

Foster, Joshua B. "Development of Pyridazine-Derivatives for the Treatment of Neurological Disorders." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1545904228813231.

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47

Husmann, Ralph [Verfasser]. "Synthesis and application of silylated pyrrolidines enantioselective organocatalytic synthesis of a-trifluoromethyl a-amino acid derivatives and copper-catalyzed multicomponent reactions / Ralph Husmann." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2011. http://d-nb.info/1018190465/34.

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48

Buabeng, Emmnauel Ramsey. "Towards the Synthesis of Novel Glycomimetics of N-Acetyl-2-amino-2-deoxy-D-mannopyranose uronic acid (D-ManNAcA) and Derivatives." Youngstown State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1471478050.

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49

Theddu, Naresh. "APPLICATIONS OF ENANTIOPURE SULFINIMINE DERIVED CHIRAL AMINE BUILDING BLOCKS FOR THE ASYMMETRIC SYNTHESIS OF TROPANE ALKALOIDS AND CYCLIC CIS BETA-AMINO ACID DERIVATIVES." Diss., Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/157444.

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Chemistry<br>Ph.D.<br>Chiral amines are ubiquitous in natural products and are found in many drugs and drug candidates. Enantiopure sulfinimines [RS(O)N=CHR1] are useful chiral building blocks for the stereoselective synthesis of amines and amine derivatives. The aim of this thesis research is to develop new methods to access chiral amine building blocks for applications in the synthesis of nitrogen-heterocycles including ring-substituted tropinones, tropanes, cyclic cis-beta-amino acid derivatives, and amino-cyclopentitols.<br>Temple University--Theses

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50

Matak, Andrija. "Synthesis and spectroscopic analysis of 4'-amino and 4'-sulfonamide chalcone derivatives and ultrastructural effects of 4'-sulfonamide boronic acid chalcone on Eimeria papillata sporozoites in vitro /." Link to Theses, 2008. http://eprint.cc.andrews.edu/38/.

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