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Journal articles on the topic 'Oro dispersible tablets'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Qureshi, Aminabi, Umaima Shaikh, Mehrunnisa Shaikh, Wafa Parkar, Maria Lal, and Mirza Salman Baig. "Solid Dispersion Incorporated Indomethacin Oro- Dispersible Tablet." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 17, no. 5 (2024): 7580–88. https://doi.org/10.37285/ijpsn.2024.17.5.4.

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Aim: This study aimed to enhance the dissolution profile of indomethacin by formulating oro-dispersible tablets, using the Solid Dispersion technique and PEG 6000 and PVP K-30 as carriers. Method: Solid Dispersion (SD) of indomethacin were prepared using the kneading method. Pre-compression studies include evaluating granules' density and flow properties, while post-compression studies assessed tablet properties such as hardness, friability, wetting time, dissolution, drug content and material interactions. Result: All pre- and post-compressional parameters were found within pre-determined lim

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Pokhrel, Gopal, Ganga Kunwar, Jun Devi Rai, Sheela Thapa, Sudip Dhakal, and Prashant Basnet. "Formulation and in-vitro Evaluation of Oro-dispersible tablets of Indomethacin." Nepal Journal of Health Sciences 2, no. 1 (2022): 90–97. http://dx.doi.org/10.3126/njhs.v2i1.47172.

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Introduction: Oro-dispersible tablets are rapidly dissolved in saliva without the need for water and are beneficial for renal impaired, bedridden and psychiatric patients. Objective: The study aimed to formulate oro-dispersible tablets of indomethacin with reduced adverse effects, better patient compliance, faster action, and convenience for patients. Methods: Oro-dispersible tablets of indomethacin were prepared using three different super disintegrants; crospovidone, croscarmellose sodium and sodium starch glycolate with three different concentrations (2.5%, 5.2%, and 7.7%) by direct compres

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3

Khobragde, Deepak, Arun Kotha, K. Ravalika, Richa Gupta, and P. Vasu Kumar. "Oro-Dispersible Tablets of Ayurvedic Powder For improving Taste, Compliance, Ease and Accuracy of administration." International Journal of Advances in Scientific Research 2, no. 6 (2016): 131. http://dx.doi.org/10.7439/ijasr.v2i6.3458.

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Most of the ayurvedic medicines are in the form of powder. Being in powder form the administration of accurate dose with ease is a problem. They may have some kind of unacceptable bitter taste. Furthermore it needs water or honey for administration and chances of spoilage and waste are more. Oro-dispersible tablet which rapidly disintegrating in mouth will be the best remedy for efficient use of ayurvedic powders. The aim of this study was to formulate oro-dispersible tablets of ayurvedic polyherbal powder Talisadi. Talisadi is a traditional Ayurvedic powder preparation well known and effectiv

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Kumar, Voleti Vijaya, Nandhini M, Sreelekhaa T, et al. "Comprehensive Review of Oro Dispersible Tablets and Co Processed Super disintegrants." Future Journal of Pharmaceuticals and Health Sciences 4, no. 1 (2024): 1–13. http://dx.doi.org/10.26452/fjphs.v4i1.548.

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Due to their ease of administration, self-administration, and improved patient compliance, solid dosage forms are most popular. The most normally utilized strong dose structures are tablets and capsules, which is challenging for pediatric and geriatric patients. Considering these prerequisites endeavors have been made to foster rapid dissolving Tablets. The solid dosage form of a medicine that dissolves in a matter of seconds when swallowed is known as orodispersible tablet. The utilization of Superdisintegrants improves the crumbling season of the tablet. Fast Dissolving Tablets are generally

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V, Vijaya Kumar. "Comprehensive Review of Oro Dispersible Tablets and Co Processed Super disintegrants." Comprehensive Review of Oro Dispersible Tablets and Co Processed Super disintegrants 4, no. 1 (2024): 1–13. https://doi.org/10.5281/zenodo.14649969.

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Due to their ease of administration, self-administration, and improved patient compliance, solid dosage forms are most popular. The most normally utilized strong dose structures are tablets and capsules, which is challenging for pediatric and geriatric patients. Considering these prerequisites endeavors have been made to foster rapid dissolving Tablets. The solid dosage form of a medicine that dissolves in a matter of seconds when swallowed is known as orodispersible tablet. The utilization of Superdisintegrants improves the crumbling season of the tablet. Fast Dissolving Tablets are generally

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Akshay Kumar S, Gowda D V, Sharadha M, and Akhila A R. "The insights on Oro-dispersible tablet." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 260–73. http://dx.doi.org/10.26452/ijrps.v11i1.1815.

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Orodispersible tablets (ODTs) were the conventional product that disintegrates or dissolves into the buccal mucosa in less than 1mins in the absence of water and without chewing. They were first acquainted with the market during the 1980s, and end up one of the quickest developing subdivisions of the oral medication conveyance industry and their items are creating at an extraordinary rate. New orodispersible tablet innovations address numerous pharmaceutical and need of patients, extending from upgraded life-cycle the executives for reasonable medicating for pediatric, aged, and mental patient

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R, Yogaraj, Surinder Kaur, and Padmaa M. Paarakh. "A Brief Introduction on Oro Dispersible Tablets." April-May 2023, no. 33 (April 10, 2023): 9–16. http://dx.doi.org/10.55529/jcpp.33.9.16.

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Oro dispersible tablets (ODTs), which have improved solubility and stability over the past three decades, have drawn a lot of interest as a superior alternative to traditional tablets and capsules. ODTs—solid dosage forms with medications that dissolve on the tongue fast, usually in a few seconds. New ODT technologies answer a wide range of pharmaceutical preparations and patient needs, to enhance the lifecycle management to straightforward dosage regimen for dysphagic, children, old, and mentally imbalanced patients. Methods for administering orally dispersible drugs are frequently used to im

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Bommana, Anusha* Girija Karike Koppula Maheshwari Ramya Sri Sura. "FORMULATION AND IN VITRO EVALUATION OF ORO DISPERSIBLE TABLETS OF LORAZEPAM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 3945–53. https://doi.org/10.5281/zenodo.1249808.

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<em>The present investigation was done on lorazepam orodispersible tablets using super disintegrants. The prepared powder blend for all formulations was found to be within limits. Tablets were compressed using rotary tablet compression machine. Post compression studies like weight variation, hardness, thickness, friability, drug content, in vitro disintegration time were carried out which were found to be within limits. In vitro drug release studies revealed that Among all formulations F4 formulation were shown maximum drug release(99.99%) at 45 min. Among these three formulations F4 was consi

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Khan, MD Abdul Aali, M. S. Sudheesh, and Rajesh Singh Pawar. "Formulation Development and Evaluation of Oro-Dispersible Tablets Based On Solid Dispersion of Cimetidine." Journal of Drug Delivery and Therapeutics 12, no. 6-S (2022): 42–46. http://dx.doi.org/10.22270/jddt.v12i6-s.5696.

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The most common problem about conventional dosage form is dysphagia (difficulty in swallowing). So, we design a new approach in a conventional dosage form which is oral dispersible tablet. Oral dispersible tablet is also called as mouth dissolving tablet, fast dissolving tablet, or oral disintegrating tablet. Oral dispersible tablet has advantage as it quickly disintegrates into saliva when it is put on the tongue. The faster the drug disintegrates or is dissolved, the faster the absorption and the quicker the therapeutic effect of drug will be attained. The objective of present study was to f

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Desai, Sushma, Chandrasekhara Rao Baru, Darupally Madhuri, et al. "Formulation and evaluation of amoxicillin Oro-dispersible tablets." International Journal of Pharmacy and Pharmaceutical Science 7, no. 1 (2025): 121–24. https://doi.org/10.33545/26647222.2025.v7.i1b.159.

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Nimisha Solanki, Arpit Gawshinde, Komal Tikariya, Umesh K. Atneriya, and Dharmendra Solanki. "A Review on Orodispersible tablet." IJPAR JOURNAL 12, no. 3 (2023): 358–61. http://dx.doi.org/10.61096/ijpar.v12.iss3.2023.358-361.

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The oral route is the most important and recommended route of drug administration. Oral route is the safest and convenient route of drug delivery because of wide range of drugs are administered through this route. Oro dispersible tablets are novel oral drug-delivery system as they have improved patient compliance and have some additional advantages compared to other oral formulation. Oral dispersible tablet are solid unit dosage forms, which disintegrate or dissolves quickly in the mouth within a minute in the presence of saliva without chewing or water. The dosage form containing super disint

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Seal, Rupam, and Dr Soundrapandian Chidambaram. "A Comprehensive Review on Progress and Challenges in Technology of Orodispersible Tablets." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 475–83. https://doi.org/10.35629/4494-0906475483.

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Numerous medications that absorb through the buccal cavity have been explored in connection to orodispersible tablet dosage forms because of their many benefits, which include stability, fast onset of action, water-free administration, precise dosing, ease of production, better bioavailability, compact packaging, and easy handling (1–5). Conventional Oro dispersible tablets have been linked to drawbacks such a lack of mechanical strength, an inclination for sugar, and the absence of an option for regulated or delayed release, if not cooked properly, an unpleasant flavor and grittiness on the t

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Baliga, S. B., B. P. Manjula, and M. Geetha. "FORMULATION AND EVALUATION OF MICROSPHERE BASED ORO DISPERSIBLE TABLETS OF SUMATRIPTAN SUCCINATE." INDIAN DRUGS 54, no. 03 (2017): 28–38. http://dx.doi.org/10.53879/id.54.03.10794.

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Sumatriptan succinate (SS) is a drug used in the treatment of migraine headaches, but suffers from low patient compliance due to its unpalatable bitter taste. The purpose of the present work was to prepare taste-masked oro dispersible tablets (ODTs) of SS by incorporating drug loaded microspheres into tablets for use in patients experiencing difficulty in swallowing. Microspheres loaded with SS were prepared by solvent evaporation technique. Eudragit EPO, a pH-sensitive aminoalkylmethacrylate copolymer, was used for coating the drug particles, acetone as solvent for the polymer and light liqui

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Alejandro, Blasco, Torrado Guillermo, and Peña M. Ángeles. "Formulation and Evaluation of Loperamide HCl Oro Dispersible Tablets." Pharmaceuticals 13, no. 5 (2020): 100. http://dx.doi.org/10.3390/ph13050100.

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This work proposes the design of novel oral disintegrating tablets (ODTs) of loperamide HCl with special emphasis on disintegration and dissolution studies. The main goal was augmenting the adherence to treatment of diseases which happen with diarrhea in soldiers who are exposed to diverse kinds of hostile environments. Optimized orally disintegrating tablets were prepared by the direct compression method from galenic development to the industrial scale technique, thanks to strategic and support actions between the Spanish Army Force Lab and the Department of Biomedical Sciences (UAH). The res

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N, M. Abdul Aziz, and Shahidul Islam Md. "Formulation Development, Preparation and Evaluation of Taste Masking Oro-Dispersible Tablet of Tiemonium Methylsulfate, by using HPMC as Taste Masking Agent." Research & Review: Drugs and Drugs Development 1, no. 2 (2019): 21–27. https://doi.org/10.5281/zenodo.3066810.

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<em>This project is developed because patients have modest taste expectations for drug product-they need to be palatable. Palatable drug products generally have moderate attributes – not too bitter, hard, gritty, chalky or irritating. Taste masking of drug by coating of granules preparations of oro-dispersible tablet in-vivo study of taste and in-vitro drug release study is enhance rapid bioavailability and rapid onset of action, improve patient comfort and compliance.</em><em> Tiemonium methylsulfate prevents the effects of acetylcholine by blocking its binding to muscarinic cholinergic

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Mahapatra, Anjan Kumar, Siddharth Dora, Sanatan Parida, Usharani Bal, Bandana Rani Jena, and Madhusmita Lenka. "Solubility enhancement of etoricoxib using inclusion complexation with cyclodextrins: formulation of oro dispersible tablets by QbD approach." Journal of Applied Pharmaceutical Research 12, no. 4 (2024): 21–30. http://dx.doi.org/10.69857/joapr.v12i4.603.

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Background: The work was intended to enhance etoricoxib's solubility and dissolution rate and then develop oro-dispersible tablets for faster onset of action. Methodology: Inclusion complexes (ICs) of the drug were obtained with β-cyclodextrin (β-CD) and hydroxypropyl β-cyclodextrin (HP β-CD) at ratios of 1:0.125, 1:0.25, 1:0.5, 1:1, and 1:2 (w/w). The selected cyclodextrin at appropriate drug carrier proportion was used to develop oro-dispersible tablets (ODTs) by direct compression, adding crospovidone as a super disintegrant. Phase solubility studies of etoricoxib were carried out by using

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N. Kendre, Prakash, Akash R. Aher, Somnath K. Vibhute, Ajinkya K. Pote, Subhash V. Deshmane, and Shirish P. Jain. "EFFECT OF HYDROPHILIC POLYMER ON DESIGN EXPERT ASSISTED ORO-DISPERSIBLE STRIP (ODS) OF ISOSORBIDE MONONITRATE." Indian Drugs 59, no. 04 (2022): 60–64. http://dx.doi.org/10.53879/id.59.04.12744.

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Oral conventional formulations like tablets, capsules and liquids have many limitations. Due to this and patient incompliance, there is a need to develop new formulations with better efficiency and stability. The aim of the present study was to develop and optimize fast dissolving Oro-dispersible strips (ODS) of isosorbide mononitrate by 32 -full factorial design. HPMC E15 (X1 ) concentration and glycerin (X2 ) concentration were selected as the independent variables, whereas, in vitro disintegration time (Y1 ), percent drug release (Y2 ) and tensile strength (Y3 ) were selected as dependent v

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Chandrasekaran, Gothainayaki, and A. N. Rajalakshmi. "Fixed dose combination products as Oro-dispersible tablets: A review." Journal of Drug Delivery and Therapeutics 9, no. 2 (2019): 563–73. http://dx.doi.org/10.22270/jddt.v9i2.2515.

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A fixed-dose combination (FDC) drug is a one that includes two or more active pharmaceutical ingredients (APIs) combined in a single dosage form, which is manufactured and distributed in fixed doses [1]. It increases patient compliance by reducing the no. of medications that a patient has to take especially for geriatric and pediatric patients. Orally disintegrating tablets (ODTs) are solid dosage forms containing a medicinal substance or active ingredient that rapidly disintegrates upon contact with saliva, typically within 30 s, eliminating the need for swallowing. It also increases patient

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Mamatha, T., Md Zubair, N. Sarah Nasreen, and Md Ahmeduddin. "Formulation and Evaluation of Oro dispersible Tablets of Fosinopril Sodium." Dhaka University Journal of Pharmaceutical Sciences 14, no. 1 (2015): 11–16. http://dx.doi.org/10.3329/dujps.v14i1.23729.

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The purpose of present research was to formulate and evaluate oro dispersible tablets (ODTs) of fosinopril sodium (FS). It has been developed at 20 mg dose and was prepared using different types of superdisintegrants such as (sodium starch glycolate, Ac-Di-Sol, crospovidone (CP), different types of subliming agents such as ammonium bicarbonate (AB) and camphor at different concentrations by direct compression method. The formulations were evaluated for uniformity of weight, content, hardness, friability, wetting time, in vitro dispersion time and dissolution rate. All formulations showed satis

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Venkatesh, DP, and CG Geetha Rao. "Formulation of taste masked oro-dispersible tablets of ambroxol hydrochloride." Asian Journal of Pharmaceutics 2, no. 4 (2008): 261. http://dx.doi.org/10.4103/0973-8398.45043.

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Nakka, Samantha A. Jayasree Praneetha. D. *. "FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF METOCLOPRAMIDE HYDROCHLORIDE." Journal of Scientific Research in Pharmacy 09, no. 08 (2020): 13–18. https://doi.org/10.5281/zenodo.7626012.

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<strong><em>ABSTRACT</em></strong> <strong> Recent advances in novel drug delivery aims to enhance the safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance. One such approach is oral disintegrating tablets. Oro-dispersible tablets are a suitable means of drug delivery system for better patient compliance, rapid onset of action, increased bioavailability. The purpose of the present research was to formulate and evaluate the mouth disintegrating tablets of metoclopramide hydrochloride. Metoclopramide

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A., Deevan Paul* P. Nagaraj E. Reshma T. Mahesh Y. Divyasree. "CHALLENGES IN NANOTECHNOLOGY DRUG DELIVERY SYSTEMS - STATE OF ART TECHNOLOGIES." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1550–58. https://doi.org/10.5281/zenodo.816203.

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The potential challenges to solve the poor solubility, limited chemical stability in vitro and in vivo after administration (i.e. short half-life), poor bioavailability and potentially strong side effects requiring drug enrichment at the site of action (targeting). This review describes the use of nanoparticulate carriers, developed in our research group, as one solution to overcome the dosage forms. The performance of ODTs depends on the technology used in their manufacture. The orally disintegrating property of these tablets is attributable to the quick ingress of water into the tablet matri

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Anand, Neeti, Lalit Singh, and Vijay Sharma. "EMERGENCE OF NATURAL SUPER-DISINTEGRNATS IN ORO-DISPERSIBLE TABLETS: AN OVERVIEW." INTERNATIONAL RESEARCH JOURNAL OF PHARMACY 4, no. 8 (2013): 33–37. http://dx.doi.org/10.7897/2230-8407.04805.

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Jagdale, Swati Changdeo, Vaibhav Uttam Gawali, Bhanudas Shankar Kuchekar, and Aniruddha Rajaram Chabukswar. "Formulation and in vitro evaluation of taste-masked oro-dispersible dosage form of diltiazem hydrochloride." Brazilian Journal of Pharmaceutical Sciences 47, no. 4 (2011): 907–16. http://dx.doi.org/10.1590/s1984-82502011000400028.

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Diltiazem hydrochloride is a calcium channel blocker generally indicated for the treatment of angina and hypertension, and it is extensively metabolized due to the hepatic metabolism. Formulation of diltiazem hydrochloride into an oro-dispersible dosage form can provide fast relief with higher bioavailability. The bitter taste of the drug should be masked to formulate it in a palatable form. In the present work, an attempt was made to mask the taste by complexation technique, with a formulation into an oro-dispersible dosage form, using superdisintegrants Doshion P544, crospovidone (CP) and so

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Rawat, Neelam, Dr Pankaj Sharma, Mr Deepak Saini, and Mrs Sunita Rani. "The Impact of Poor-Tasting Pediatric Medications on Acceptability, Adherence, and Treatment Outcomes." International Journal of Enhanced Research in Medicines & Dental Care 12, no. 06 (2025): 22–27. https://doi.org/10.55948/ijermdc.2025.0604.

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There are various tablet formulations available such as sugar-coated, film-coated, and enteric-coated tablets, many of which are designed for different routes of administration including sublingual or buccal. While each formulation offers specific advantages, patient compliance often poses a challenge, particularly due to the bitter taste of numerous medications. Oro dispersible tablets (ODTs) that include taste-masking strategies are especially beneficial in addressing these issues. These formulations are not only effective in masking unpleasant Flavors but also enhance patient adherence—espe

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Rangu, Nirmala, B. Chaitanya Kumari, Ganesh Akula, and A. Jaswanth. "Formulation and Evaluation of Oro Dispersible Tablets of Atenolol by Sublimation Method." Asian Journal of Pharmacy and Technology 8, no. 1 (2018): 1. http://dx.doi.org/10.5958/2231-5713.2018.00001.6.

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Daraghmeh, Nidal, Babur Chowdhry, Stephen Leharne, Mahmoud Al Omari, and Adnan Badwan. "Co-Processed Chitin-Mannitol as a New Excipient for Oro-Dispersible Tablets." Marine Drugs 13, no. 4 (2015): 1739–64. http://dx.doi.org/10.3390/md13041739.

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POOJA, YADAV, SHARMA RAMAKANT, KHAN SHABNAM, PATEL JEEVAN, and PATEL RAKESH. "Development and estimation of an oro-dispersible anti-malarial dosage form for pediatric patient." World Journal of Biology Pharmacy and Health Sciences 13, no. 1 (2023): 250–57. https://doi.org/10.5281/zenodo.7947752.

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Artemether-Lumefantrine tablets are inconvenient for caregivers to administer as they need to be crushed and mixed with water or food for infants and young children. Further, in common with other anti-malarial, they have a bitter taste, which may result in children spitting the medicine out and not receiving the full therapeutic dose. There was a clear unmet medical need for a formulation of AL specifically designed for children.

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Shashank Khailkhura, Bhavana Singh, Deepika Joshi, and Nidhi Semwal. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. http://dx.doi.org/10.30574/wjbphs.2022.11.3.0124.

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Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

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Shashank, Khailkhura, Singh Bhavana, Joshi Deepika, and Semwal Nidhi. "Orally disintegrating tablet: A review." World Journal of Biology Pharmacy and Health Sciences 11, no. 3 (2022): 018–25. https://doi.org/10.5281/zenodo.7180875.

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Orally dispersive tablets are solid dosage forms that dissolve in the mouth in within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due to its fast breakdown, which also causes the effects to start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young patients with undeveloped muscular and nervous systems, patients with hand tremors, and patients who travel often. It provides high stability, precise dosage, efficient manufacture, and smaller packi

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Mahale, Sunita, Manisha Tayde, Yogita G. Ahire, Rupali S. Dhikale, and Vishal S. Gulecha. "Design and evaluation of cost-effective oro-dispersible tablets of venlafaxine hydrochloride by effervescent method." Journal of Applied Pharmaceutical Research 12, no. 3 (2024): 46–55. http://dx.doi.org/10.69857/joapr.v12i3.501.

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Background: Venlafaxine hydrochloride (VFH) is an antidepressant drug with poor bioavailability due to extensive first-pass metabolism. Objective: In the present study, oro-dispersible VFH tablets were prepared using an effervescent method to enhance patient compliance using a design of experiment (DoE) approach. Methods: A two-factor, three-level 32 full factorial design was applied to investigate the combined effect of two formulation variables: the amount of treated agar and effervescent material (mixture of sodium bicarbonate, citric acid and tartaric acid) on disintegration time and %drug

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Akula, Priyanka. "Formulation and Evaluation Oral Dispersible Tablets of Vidarabine." International Journal of Pharmacy and Biological Sciences (IJPBS) 13, no. 3 (2023): 36–47. https://doi.org/10.5281/zenodo.10099936.

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<strong>Abstract</strong>In the present work, taste masking of Vidarabine was carried out by using HP-β-CD inclusion complex. These taste-masked complexes were further formulated into the Oro dispersible tablet by the direct compression method using Ac-Di-Sol and Avicel as a super disintegrant. Vidarabine is used in the treatment of AIDS. This research has described the production of a taste masked dosage form from initial determination of threshold bitterness concentration of the pure drug through to the development of a final taste masked prototype formulation. It was found that the taste ma

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Juhi, Bhadoria, and Likhariya Manoj. "A Review on Orodispersible Tablet by Using Hibiscus rosa sinesis as Natural Superdisintegrant." International Journal of Pharmaceutical Sciences and Medicine 7, no. 6 (2022): 59–69. http://dx.doi.org/10.47760/ijpsm.2022.v07i06.003.

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Oral delivery is current standard in the pharmaceutical industry wherever it is regarded as the safest, most suitable and most economical method of drug delivery. The oral cavity is an attractive site for the administration of drugs because of ease of administration. Oro-dispersible drug delivery system are Novel Drug Delivery techniques that make the tablets disintegrate in the mouth without chewing and water, and immediate release and enhanced bioavailability, with better patient compliance. Orodispersible tablets (ODTs), also known as fast melt, quick melts, fast disintegrating have the uni

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Gupta, Richa, Ravalika K, P. Vasu Kumar, Arun Kotha, and Deepak Khobragde. "FORMULATION DEVELOPMENT OF ORO-DISPERSIBLE TABLETS OF AYURVEDIC POWDER FORMULATION FOR EFFICIENT USE." International Research Journal of Pharmacy 7, no. 6 (2016): 48–50. http://dx.doi.org/10.7897/2230-8407.07662.

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Gottemukkula, Lakshmi Devi, Raghuveer Pathuri, and Sunitha Sampathi. "Dolutegravir Solid Dispersions as Oro-Dispersible Tablets: To Ameliorate the Integrase Inhibition Effect." Indian Journal of Pharmaceutical Education and Research 59, no. 3s (2025): s863—s873. https://doi.org/10.5530/ijper.20255690.

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Akshay Kumar S, Gowda D V, Sharadha M, and Famna Roohi N K. "Formulation and evaluation of third-generation Cefpodoxime proxetil as an Oro-dispersible tablets for treating infections." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 921–32. http://dx.doi.org/10.26452/ijrps.v11i1.1916.

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The main problems to humans include the infection caused in the respiratory tract and urinary tract, namely respiratory tract infection (RTI) and urinary tract infection (UTI). Cefpodoxime Proxetil drug is available in the market that has a problem with drug release profile and flows property. To overcome this problem, the compacted powder form made into a micro-ionized form for its better flow property and drug release by using a direct compression technique. The study was based on the aim to evaluate and formulate oro-dispersible tablets as an effective approach via orally for the treatment

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POOJA YADAV, RAMAKANT SHARMA, SHABNAM KHAN, JEEVAN PATEL, and RAKESH PATEL. "Development and estimation of an oro-dispersible anti-malarial dosage form for pediatric patient." World Journal of Biology Pharmacy and Health Sciences 13, no. 1 (2023): 250–57. http://dx.doi.org/10.30574/wjbphs.2023.13.1.0029.

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Artemether-Lumefantrine tablets are inconvenient for caregivers to administer as they need to be crushed and mixed with water or food for infants and young children. Further, in common with other anti-malarial, they have a bitter taste, which may result in children spitting the medicine out and not receiving the full therapeutic dose. There was a clear unmet medical need for a formulation of AL specifically designed for children.

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Ahmad, Muhammad Masood, Tanveer Ahmed Khan, and Kasatkin Valery. "PRELIMINARY STUDIES ON THE PHYSICAL PARAMETERS OF ORODISPERSIBLE TABLETS USING SUPERDISINTEGRANTS." Hamdard Journal of Pharmacy 1, no. 1 (2021): 23–31. http://dx.doi.org/10.61744/hjp.v1i1.57.

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There are various routes of drug administration available such as oral, sublingual, inhalation, and rectal. Among all, the oral route of drug administration is most widely used. Tablet is the most popular dosage form among all existing dosage forms. The most conventional tablets are immediate release but these tablets are only suitable for drugs with high solubility and high permeability. In this study, five different Orodispersible tablet formulations were prepared. Various Natural and Synthetic super disintegrants were used in all formulations including Plantago Ovata (F1), Sodium Alginate (

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Lakshmi, P. K., Ginnarapu Supraja, and Ruhi Anjum. "FORMULATION AND EVALUATION OF ARIPIPRAZOLE ORO-DISPERSIBLE TABLETS: OPTIMISATION THROUGH FACTORIAL DESIGN OF EXPERIMENTS." Journal of Pharmaceutical & Scientific Innovation 8, no. 1 (2019): 32–37. http://dx.doi.org/10.7897/2277-4572.081123.

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Choudhary, Nilesh, and Jasmine Avari. "Formulation and evaluation of taste mask pellets of granisetron hydrochloride as oro dispersible tablet." Brazilian Journal of Pharmaceutical Sciences 51, no. 3 (2015): 569–78. http://dx.doi.org/10.1590/s1984-82502015000300009.

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Orally disintegrating systems have carved a niche amongst the oral drug delivery systems due to the highest compliance of the patients, especially the geriatrics and pediatrics. In addition, patients suffering from dysphagia, motion sickness, repeated emesis and mental disorders prefer these medications because they cannot swallow large quantity of water. Further, drugs exhibiting satisfactory absorption from the oral mucosa or intended for immediate pharmacological action can be advantageously formulated in these dosage forms. However, the requirements of formulating these dosage forms with m

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Solanki, Nimisha, Arpit Gawshinde, Komal Tikariya, Dharmendra Solanki, and Umesh K. Atneriya. "Formulation and Evaluation of Oral Dispersible Tablet of Poorly Water-Soluble Drug ‘Glimepiride’ by Using Solubility Enhancement Technique." International Journal of Pharmaceutical Sciences and Medicine 9, no. 1 (2024): 62–72. http://dx.doi.org/10.47760/ijpsm.2024.v09i01.005.

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The present study is regarding Glimepiride (GMP) is poorly water-soluble drug. According to the BCS, Glimepiride undergoes Class II - High Permeability and Low Solubility. The objective of the research project is to enhance the solubility of Glimepiride by using solubility enhancement techniques. The endeavor is to improve its solubility by using super disintegrating agent to enhance the ability of disintegration of Oro dispersible tablet. To enhance of solubility of GMP, our select the method i.e. solid dispersion technique because Solid dispersion is an effective way of improving the dissolu

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Haslund-Krog, Sissel Sundell, Inger Merete Jørgensen, Kim Dalhoff, and Helle Holst. "Acceptability of Prednisolone in an Open-Label Randomised Cross-Over Study—Focus on Formulation in Children." Children 9, no. 8 (2022): 1236. http://dx.doi.org/10.3390/children9081236.

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Developing acceptable medicines for children is a complicated task. Several factors must be considered, including age, physiology, texture preference, formulation, and legal framework among others. In the development of new paediatric medicines, these factors are assessed. However, for older medicines, e.g., prednisolone, acceptability is still a challenge. This study was an open-label randomised three-arm cross-over study investigating different formulations of prednisolone (crushed tablets, whole tablets, and oral solution) in paediatric patients with asthma and asthma-like symptoms. Partici

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Pratiksha, Jagtap Vaibhav Changediya. "Formulation Development And Evaluation Of Mentha Spicata Leaf Powder Orodispersible Tablet." International Journal of Pharmaceutical Sciences 2, no. 10 (2024): 566–82. https://doi.org/10.5281/zenodo.13920434.

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This research was focuses on the formulation development and evaluation of Oro-dispersible tablets (ODTs) containing Mentha spicata leaf powder, aiming to explore its potential as a novel herbal formulation for oral administration. Mentha spicata, commonly known as spearmint, possesses various pharmacological properties, including antimicrobial, antioxidant, and anti-inflammatory effects, which make it a promising candidate for pharmaceutical applications. The formulation process involves the wet granulation method for Mentha spicata leaf powder tablet. The Tablet was evaluated for its physica

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Kumar, Mahapatra Anjan, Padala Narasimha Murthy, Nagampalli Haritha Sameeraja, and Palei Narahari Narayan. "Dissolution Rate Enhancement of Entacapone and Formulation of its Oro- Dispersible Tablets: Applying Statistical Design." Indian Journal of Pharmaceutical Education and Research 50, no. 4 (2016): 549–62. http://dx.doi.org/10.5530/ijper.50.4.7.

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Vachan Y, Y Anand Kumar, Srikanth N, and Pavan Kumar. "Quality by design approach for optimizing the formulation properties of escitalopram oxalate Oro-dispersible tablets." Open Access Research Journal of Engineering and Technology 7, no. 2 (2024): 126–41. https://doi.org/10.53022/oarjet.2024.7.2.0062.

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The quality by design (QbD) approach was applied for optimizing the formulation of Escitalopram oxalate (ES) orodispersible tablets (ODTs) using Design-Expert Software. To Optimize ES-ODTs a quality target product profile was established in which critical quality attributes (CQAs) such as wetting time, dispersion time, disintegration time and drug release rates were defined and quantified. As critical formulation parameters (CFP) that were evaluated for their effect on the CQA. Percentage of Crospovidone (CP) and Croscaramellose (CCS) were choosen. Response surface methodology (RSM) such as Ce

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Khobragade, Deepak, Sunil Kumar, Arun Kotha, Richa Gupta, and K. Ravalika. "Formulation and in vivo evaluation of oro-dispersible tablets of ayurvedic powders Sitopaladi and Talisadi." Research Journal of Pharmaceutical Dosage Forms and Technology 8, no. 3 (2016): 177. http://dx.doi.org/10.5958/0975-4377.2016.00024.0.

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Mathies, Daniel, Tsuneo Oyama, Ingo Steinbrück, and Franz Ludwig Dumoulin. "Topical oro-dispersible budesonide tablets for stricture prevention after near circumferential ESD for esophageal squamous cell cancer – a case report." Zeitschrift für Gastroenterologie 59, no. 05 (2021): 454–56. http://dx.doi.org/10.1055/a-1409-1076.

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Abstract Background Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70–80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local injections and/or systemic steroids are given for prevention. Case report We present here the case of a 78-year-old male patient who had a near circumferential endoscopic submucosal dissection for a pT1a mm, L0, V0, R0, G2 esophageal squamous cell cancer. At the end of endoscopic resection, 80 mg of triamcinolone was injected locally. The patient

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K., Ramanji Reddy* Dr. S. Jaya K. Himani Dr. Chandaka Madhu. "FORMULATION AND EVALUATION OF CEFUROXIME AXETIL ORODISPENSIBLE TABLETS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 745–54. https://doi.org/10.5281/zenodo.1174197.

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The Study was undertaken with an aim to formulate oro-dispersible tablets of cefuroxime axetil by using superdisintegrants like crospovidone, sodium starch glycolate and Ac-di-sol . Different formulations were prepared varying the superdisintegrant concentration. Preformulation study of the tablet blend was carried out, the tablet blends showed good flowing properties directing for the further course of formulation. The tablets were prepared by direct compression method.Tablets were evaluated for postformulation studies like hardness, weight variation, friability, wetting time, in vitro disint

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K., Ramanji Reddy* Dr. S. Jaya Chinnapangu Rajeswari Dr. Chandaka Madhu. "FORMULATION AND EVALUATION OF FLOATING TABLETS OF FAMCICLOVIR USING VARIOUS HYDROPHILIC AND HYDROPHOBIC POLYMERS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 745–54. https://doi.org/10.5281/zenodo.1174203.

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The Study was undertaken with an aim to formulate oro-dispersible tablets of cefuroxime axetil by using superdisintegrants like crospovidone, sodium starch glycolate and Ac-di-sol . Different formulations were prepared varying the superdisintegrant concentration. Preformulation study of the tablet blend was carried out, the tablet blends showed good flowing properties directing for the further course of formulation. The tablets were prepared by direct compression method.Tablets were evaluated for postformulation studies like hardness, weight variation, friability, wetting time, in vitro disint

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Khan, Amjad. "Prediction of quality attributes (mechanical strength, disintegration behavior and drug release) of tablets on the basis of characteristics of granules prepared by high shear wet granulation." PLOS ONE 16, no. 12 (2021): e0261051. http://dx.doi.org/10.1371/journal.pone.0261051.

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High shear wet granulation is commonly applied technique for commercial manufacturing of tablets. Granulation process for tablets manufacturing is generally optimized by hit and trial which involves preparation of granules under different processing parameters, compression of granules and evaluation of the resultant tablets; and adjustment is made in granulation process on the basis of characteristics of tablets. Objective of the study was to optimize the process of high shear wet granulation and prediction of characteristics of tablets on the basis of properties of granules. Atenolol granules

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