Academic literature on the topic 'Oromucosal'

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Journal articles on the topic "Oromucosal"

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Garnock-Jones, Karly P. "Oromucosal Midazolam." Pediatric Drugs 14, no. 4 (2012): 251–61. http://dx.doi.org/10.2165/11209320-000000000-00000.

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Szymańska, Emilia, Joanna Potaś, Marcin Baranowski, et al. "Evaluation of Oromucosal Natural Gum-Based Emulgels as Novel Strategy for Photodynamic Therapy of Oral Premalignant Lesions." Pharmaceutics 15, no. 10 (2023): 2512. http://dx.doi.org/10.3390/pharmaceutics15102512.

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Photodynamic therapy (PDT) recently has been shown as a promising option in the treatment of premalignant lesions of the soft oral tissues. Effective delivery of photosensitizer is challenging due to poor drug adherence to the oromucosal epithelium. In the present work, emulgels composed of natural polysaccharide gums (tragacanth, xanthan and gellan) were evaluated as novel oromucosal platforms of delta-aminolevulinic acid (ALA) for PDT. Apart from mucoadhesive and textural analysis, the specific steps involved studies on drug penetration behavior and safety profile using a three-dimensional h
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Xu, Dan, Chunmei Lan, Juan Kou, Shuxia Yao, Weihua Zhao, and Keith M. Kendrick. "Oromucosal Administration of Oxytocin: The Development of ‘Oxipops’." Pharmaceutics 16, no. 3 (2024): 333. http://dx.doi.org/10.3390/pharmaceutics16030333.

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The role of the hypothalamic neuropeptide oxytocin in influencing the brain and behavior has been the subject of widespread research over the last few decades due, most notably, to its reported involvement in promoting social cognition and motivation, reducing anxiety, and relieving pain. It is also increasingly being considered as an important therapeutic intervention in a variety of disorders with social dysfunction as a symptom. While, in recent years, studies in humans have administered oxytocin primarily via an intranasal route, since it may partly enter the brain directly this way via th
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Suragimath, Girish, Satish R. Patil, Manoj Patil, S. R. Ashwinirani, and Disha Suragimath. "Oromucosal Changes in Patients Receiving Radiotherapy for Head and Neck Cancers." Journal of Datta Meghe Institute of Medical Sciences University 19, no. 3 (2024): 555–61. http://dx.doi.org/10.4103/jdmimsu.jdmimsu_221_24.

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Abstract Background: Head-and-neck cancers (HNCs) rank as the seventh malignancies on a global scale. Radiotherapy is a modality for treating these cancers, causing unwanted harmful effects on the surrounding tissues. Aims and Objectives: The objective of this study was to evaluate the oromucosal changes during radiotherapy in HNC patients and correlate with radiation dosages. Materials and Methods: A total 90 HNC patients between 25 and 75 years of age, receiving radiotherapy were included. Two groups of patients were created depending on the radiation dosage, Group 1 (n = 62; 50–60 Gray [Gy]
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Dmytriieva, O. O., I. F. Bielenichev та B. S. Burlaka. "Optimisation of the composition of safe dental gel with IL-1β antagonist for the treatment of inflammatory periodontal diseases". Zaporozhye Medical Journal 26, № 2 (2024): 134–43. http://dx.doi.org/10.14739/2310-1210.2024.2.292521.

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Aim. The study aims to develop the composition of the oromucosal gel with the IL-1β interleukin antagonist for complex treatment of inflammatory periodontal diseases. Materials and methods. Experimental studies were conducted based on the Department of Medicines Technology of Zaporizhzhia State Medical and Pharmaceutical University and the Training Medical and Laboratory Center of Zaporizhzhia State Medical and Pharmaceutical University of the Ministry of Health of Ukraine. As an active component, in the recipe of oromucosal gel, used antagonist of the interleukin IL-1B. Excipients: D-pantheno
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Dubashynskaya, Natallia, Valentina Petrova, and Yury Skorik. "Biopolymer Drug Delivery Systems for Oromucosal Application: Recent Trends in Pharmaceutical R & D." International Journal of Molecular Sciences 25, no. 10 (2024): 5359. http://dx.doi.org/10.3390/ijms25105359.

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Oromucosal drug delivery, both local and transmucosal (buccal), is an effective alternative to traditional oral and parenteral dosage forms because it increases drug bioavailability and reduces systemic drug toxicity. The oral mucosa has a good blood supply, which ensures that drug molecules enter the systemic circulation directly, avoiding drug metabolism during the first passage through the liver. At the same time, the mucosa has a number of barriers, including mucus, epithelium, enzymes, and immunocompetent cells, that are designed to prevent the entry of foreign substances into the body, w
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Kumar, Sandeep, Prashant Mishra, Shilpa Warhekar, Bhuvnesh Airen, Deepika Jain, and Shaijal Godha. "Oral Health Status and Oromucosal Lesions in Patients Living with HIV/AIDS in India: A Comparative Study." AIDS Research and Treatment 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/480247.

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Oral health status of HIV positive individuals is in poor condition which may be a sequela of variety of factors. This study was aimed at assessing and comparing the oral health status and oromucosal lesions between HIV positive and negative individuals in India. A total of 126 HIV positive and 532 HIV negative individuals were recruited for the study. Oral health status and oromucosal lesions were recorded using WHO oral health assessment form (1997). Data was analyzed using chi-square and independent sample student’sttest. Majority (85.7%) of people suffering from HIV belonged to lower socio
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Beilharz, Manfred W., Martin J. Cummins, Alayne L. Bennett, and Joseph M. Cummins. "Oromucosal Administration of Interferon to Humans." Pharmaceuticals 3, no. 2 (2010): 323–44. http://dx.doi.org/10.3390/ph3020323.

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Eid, Pierre, Jean-Francois Meritet, Chantal Maury, Ahmed Lasfar, Dominique Weill, and Michael G. Tovey. "Oromucosal Interferon Therapy: Pharmacokinetics and Pharmacodynamics." Journal of Interferon & Cytokine Research 19, no. 2 (1999): 157–69. http://dx.doi.org/10.1089/107999099314306.

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Haddad, Fatma, Ghadeer Dokmak, and Rafik Karaman. "The Efficacy of Cannabis on Multiple Sclerosis-Related Symptoms." Life 12, no. 5 (2022): 682. http://dx.doi.org/10.3390/life12050682.

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Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in the central nervous system. MS is characterized by its most common symptoms of spasticity, muscle spasms, neuropathic pain, tremors, bladder dysfunction, dysarthria, and some intellectual problems, including memory disturbances. Several clinical studies have been conducted to investigate the effects of cannabis on the relief of these symptoms in MS patients. The efficacy of Cannabis sativa (C. Sativa) in the management of MS outcomes such as spasticity, pain, tremors, ataxia, bladder functions, sleep, quality
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Dissertations / Theses on the topic "Oromucosal"

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Franceschini, I. "INNOVATIVE MATERIALS FOR THE DESIGN OF OROMUCOSAL PREPARATIONS." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/348030.

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The present Ph.D. thesis proposed to investigate the feasibility of using polymethylmethacrylates salts (XPPMs) as innovative materials for the production of oromucosal preparations. The overall experimental work carried out permitted to demonstrate the versatility of using these polymers, also in combination with maltodextrins (MDX), to obtain orodispersible films (ODFs) and mucoadehsive tablets obtained by freeze-drying technique. The goals have been accomplished by a preliminary deepening of ODFs characteristics. Films formulated by using MDX were used as a model, since their use for ODFs
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Preis, Maren Katherina [Verfasser], Jörg [Akademischer Betreuer] Breitkreutz, and Peter [Akademischer Betreuer] Kleinebudde. "Oromucosal film preparations for pharmaceutical use - formulation development and analytical characterization / Maren Katherina Preis. Gutachter: Peter Kleinebudde. Betreuer: Jörg Breitkreutz." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2014. http://d-nb.info/1056035986/34.

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Jones, Amanda Louise. "How does cannabis affect appetite and mood? : the acute effects of oromucosal administration of a phytocannabinoid, 9-tetrahydrocannabinol (THC), on appetite and mood in healthy volunteers." Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511046.

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Bredenberg, Susanne. "New Concepts in Administration of Drugs in Tablet Form : Formulation and Evaluation of a Sublingual Tablet for Rapid Absorption, and Presentation of an Individualised Dose Administration System." Doctoral thesis, Uppsala University, Department of Pharmacy, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3433.

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<p>This thesis presents two new concepts in oral drug administration and the results of evaluation of some relevant formulation factors.</p><p>Investigation into improving the homogeneity of mixtures for tableting indicated that it may be possible to obtain interactive dry mixtures of micronised drugs containing drug proportions as low as 0.015% w/w. By studying the relationship between disintegration time and tensile strength, it was found that the microstructure surrounding the disintegrant particles may influence the disintegration process. Therefore, avoidance of excipients which are highl
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Campos, João Carlos Costa. "Dual-purpose oromucosal films and tablets for the local management of oral mucositis." Doctoral thesis, 2020. https://hdl.handle.net/10216/129507.

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Campos, João Carlos Costa. "Dual-purpose oromucosal films and tablets for the local management of oral mucositis." Tese, 2020. https://hdl.handle.net/10216/129507.

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Yang, Yung-Rong, and 楊韻蓉. "Immunoregulation of Oromucosal Low-Dose rh-Interferon in Pigs, and the Protective Efficiency Against PRRSV and/or PCV2 infections." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/34997069518783773184.

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碩士<br>國立中興大學<br>獸醫病理生物學研究所<br>99<br>Porcine circovirus-associated diseases (PCVAD) is a multifactor disease syndrome, in which porcine circovirus type 2 (PCV2) has been regarded as an essential causative agent and porcine reproductive and respiratory syndrome virus (PRRSV) plays the most common synergic pathogen to trigger PCVAD. Besides PCV2 vaccination, environmental and managerial improvement, and elevation of innate immunity may be also very important in control PCVAD and respiratory infections. The study objectives were to evaluate the efficacy of oromucosal administration of low-dose rec
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Book chapters on the topic "Oromucosal"

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Moisset, Xavier. "Pain and Multiple Sclerosis." In Neuropathic Pain, edited by Nadine Attal and Didier Bouhassira. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197616345.003.0022.

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Abstract This chapter presents the case of a middle-aged woman with multiple sclerosis who reports pain of the lower limbs associated with lower limb weakness, spasticity, and fatigue. She also presents with sudden, brief painful episodic spasms of the right leg several times a day, which corresponds to painful tonic spasms. Patients with multiple sclerosis report multiple pain types, including central neuropathic pain, but also spasticity and painful tonic spasms. The latter can be induced or reproduced by hyperventilation and may respond to carbamazepine and oxcarbazepine. The treatment of s
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"Oral medicine." In Oxford Handbook for the Dental Foundation and Core Training Programmes, edited by Chris Barker and Hemash Shah. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780198767824.003.0007.

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Abstract This chapter provides an understanding of the pathological basis for oromucosal disease, changes affecting the oral mucosa, oral cancer, salivary gland disorders, and facial pain. The chapter provides information for Dental Core trainees in oral medicine and for all practitioners presented with these conditions to identify and provide appropriate management. Anatomical variants of normal tissue are explained, investigations used in oral medicine are also described including imaging techniques. It enables readers to provide assessment and examination of the head and neck, prescribe app
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Korpivaara, Mira, Karen Overall, and Melissa Hamel. "Usability evaluation of a new oromucosal gel dosing syringe for dogs." In BSAVA Congress Proceedings 2023. British Small Animal Veterinary Association, 2023. http://dx.doi.org/10.22233/9781913859152.48.3.

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Patel, Jeshika B., Sejal M. Khuman, and Saloni S. Desai. "ORALLY DISINTEGRATING FILM – A MODERN APPROACH IN DRUG DELIVERY SYSTEM." In Emerging Pharmaceutical Sciences: Today and Tomorrow. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/nbennurch335.

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Innovative methods of drug delivery have gained more attention in recent times in an effort to boost patient compliance, safety, and effectiveness. The search and creation of novel chemical molecule is a expensive and timeconsuming. As a result, the pharmaceutical businesses are concentrating on creating novel drug delivery technologies for their current product lines. The quick disintegrating oral film is one such delivery method that has grown in popularity among geriatric and pediatric patients. When inserted in the mouth, orally disintegrating film or strips retaining the dosage form to be
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Korpivaara, Mira, John Aspegrén, Mirja Huhtinen, and Karen Overall. "Oromucosal dexmedetomidine gel for alleviation of fear and anxiety in dogs during minor veterinary or husbandry procedures." In BSAVA Congress Proceedings 2017. British Small Animal Veterinary Association, 2017. http://dx.doi.org/10.22233/9781910443439.65.3.

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Conference papers on the topic "Oromucosal"

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Herrlich, S., T. Lorenz, M. Marker, S. Spieth, S. Messner, and R. Zengerle. "Miniaturized osmotic pump for oromucosal drug delivery with external readout station." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6092067.

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