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Journal articles on the topic 'Oropharyngeal flora'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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1

Karaman, Emin, Ozgun Enver, Yalcin Alimoglu, et al. "Oropharyngeal flora changes after tonsillectomy." Otolaryngology–Head and Neck Surgery 141, no. 5 (2009): 609–13. http://dx.doi.org/10.1016/j.otohns.2009.07.010.

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Objective: We aimed to investigate the effect of tonsillectomy on oropharyngeal flora in children who underwent tonsillectomy for chronic recurrent tonsillitis. Study Design and Setting: A prospective study was performed comprising patients with chronic recurrent tonsillitis who underwent tonsillectomy at the Department of Otolaryngology, Cerrahpasa Medical School. Incisional core biopsies of excised tonsils were also performed. Swabs and core biopsy specimens were transferred and maintained in Stuart's medium and sent to the Department of Microbiology and Clinical Microbiology at Cerrahpasa M

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Isha, Katyal, Ankle N.R., Patil Prashant, and K. Damam Sachin. "Changing paradigms in critical care: Variation in Oropharyngeal Microbiota as a deciding factor to Antibiotic Resistance in ICU patients." British Journal of Medical and Health Research 10, no. 06 (2023): 13–19. https://doi.org/10.5281/zenodo.8254332.

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ABSTRACT Oropharyngeal colonization by pathogenic organisms especially in the initial crucial days of ICU admission, is the main cause of predisposition to nosocomial infections. Hence, identifying bacterial flora, in respect to hospitalization will help in further management to prevent morbidity and mortality of these patients. Determining changes in bacterial flora in oropharynx of patients with nasogastric tube, admitted in ICU. One year prospective observational study including 40 patients between 18 and 70 years, Group A 20 cases- with nasogastric tube in situ, Group B 20 controls includi

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O’Neal, Pamela V., Nicole Brown, and Cindy Munro. "Physiologic Factors Contributing to a Transition in Oral Immunity among Mechanically Ventilated Adults." Biological Research For Nursing 3, no. 3 (2002): 132–39. http://dx.doi.org/10.1177/1099800402003003003.

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Ventilator-associated pneumonia (VAP), a specific type of nosocomial pneumonia, occurs in approximately 21% of patients in intensive care, and the mortality can be as high as 71%. VAP causes considerable mortality and morbidity, and it exponentially increases health care costs. The incidence of VAP is associated with oropharyngeal colonization of gram-negative bacteria. Within 48 h of hospital admission, the composition of the oropharyngeal flora of critically ill patients undergoes a change fromthe usual gram-positive streptococci and dental pathogens to a predominant gram-negative flora that

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Abu Shara, K. A., M. A. Ghareeb, S. Zaher, A. Mobacher, M. Ch Khalifa, and S. Z. Saleh. "Radiotherapeutic effect on oropharyngeal flora in patients with head and neck cancer." Journal of Laryngology & Otology 107, no. 3 (1993): 222–27. http://dx.doi.org/10.1017/s0022215100122686.

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The affect of radiotherapy on oropharyngeal bacterial flora was studied in the hope that this might help in controlling post-operative infections in previously irradiated patients. Eighty patients were included from whom swabs were taken before and at the end of irradiation, Swabs were also taken two weeks after treatment in the last 40 patients. Thirty healthy controls were included.It was found that coagulase positive Staphylococcus aureus, β-haemolytic streptococci, Candida albicans, B. proteus, and Pseudomonas aeruginosa, were significantly increased at the end of irradiation, while Klebsi

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5

Song, Xi, Liufang Zhou, Lin Tang, Zhuang Ma, Xincheng Mao, and Junmin Peng. "Clinical effect of compound lidocaine cream on oropharyngeal flora under general anesthesia." Materials Express 12, no. 8 (2022): 1081–86. http://dx.doi.org/10.1166/mex.2022.2249.

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To observe the effect of compound lidocaine cream on oropharyngeal flora under general anesthesia, the front-end tracheal tube or laryngeal mask was coated with 410 cases under general anesthesia were chosen as endotracheal intubation group (T) and Laryngeal mask group (L) from Jan, 2022 to June, 2022. Both were separately grouped into blank control (M), liquid paraffin oil (P) and Compound lidocaine cream (C). Based on the grouping, patients’ throat swab samples were collected for bacterial culture through tracheal catheter. Oral normal flora and pathogenic bacteria from M and P were compared

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Dilworth, J. P., R. J. White, and E. M. Brown. "Oropharyngeal flora and chest infection after upper abdominal surgery." Thorax 46, no. 3 (1991): 165–67. http://dx.doi.org/10.1136/thx.46.3.165.

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Karabay, Oğuz, Hande Toptan, Elif Köse, Ertuğrul Güçlü, and Mehmet Köroğlu. "Comparison of Mouthwash and Naso-Oropharyngeal Swab Samples in the Diagnosis of COVID-19." Flora the Journal of Infectious Diseases and Clinical Microbiology 26, no. 3 (2021): 378–83. http://dx.doi.org/10.5578/flora.20219705.

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8

Leibovitz, Arthur, Yehuda Carmeli, and Refael Segal. "Effect of Various Antibacterial Preparations on the Pathogenic Oral Flora in Elderly Patients Fed via Nasogastric Tube." Antimicrobial Agents and Chemotherapy 49, no. 8 (2005): 3566–68. http://dx.doi.org/10.1128/aac.49.8.3566-3568.2005.

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ABSTRACT Oropharyngeal colonization by pathogenic gram-negative bacilli (GNB) and Staphylococcus aureus is associated with aspiration pneumonia. Decolonization in high-risk populations may be important. We prospectively evaluated six antiseptic compounds in nasogastric tube-fed frail elderly patients; only polymixine reduced oropharyngeal colonization with GNB. None had an effect on S. aureus colonization.

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9

Berg, Hans F., Jeroen H. T. Tjhie, Gert-Jan Scheffer, et al. "Emergence and Persistence of Macrolide Resistance in Oropharyngeal Flora and Elimination of Nasal Carriage of Staphylococcus aureus after Therapy with Slow-Release Clarithromycin: a Randomized, Double-Blind, Placebo-Controlled Study." Antimicrobial Agents and Chemotherapy 48, no. 11 (2004): 4183–88. http://dx.doi.org/10.1128/aac.48.11.4183-4188.2004.

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ABSTRACT To investigate the effect of slow-release (SR) clarithromycin on colonization and the development of resistance in oropharyngeal and nasal flora, a double-blind, randomized, placebo-controlled trial was performed with 8 weeks of follow-up. A total of 296 patients with documented coronary artery disease were randomized in the preoperative outpatient clinic to receive a daily dose of SR clarithromycin (500 mg) (CL group) or placebo tablets (PB group) until the day of surgery. Nose and throat swabs were taken before the start of therapy, directly after the end of therapy, and 8 weeks lat

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10

THOMAS, SARA, RAJAGOPALAN RAMAN, JOHN IDIKULA, and NARAYANAN BRAHMADATHAN. "Alterations in oropharyngeal flora in patients with a nasogastric tube." Critical Care Medicine 20, no. 12 (1992): 1677–80. http://dx.doi.org/10.1097/00003246-199212000-00013.

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11

Renard, Kyle W., Margaret Marling-Cason, R. G. Sheehan, and P. A. Mackowiak. "Effects of cancer chemotherapy on the human aerobic oropharyngeal flora." Infection 14, no. 5 (1986): 237–42. http://dx.doi.org/10.1007/bf01644270.

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12

Le, Thuy My, Maroeska M. Rovers, Birgit K. van Staaij, Emma H. van den Akker, Arno W. Hoes, and Anne G. M. Schilder. "Alterations of the Oropharyngeal Microbial Flora After Adenotonsillectomy in Children." Archives of Otolaryngology–Head & Neck Surgery 133, no. 10 (2007): 969. http://dx.doi.org/10.1001/archotol.133.10.969.

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13

Frandah, Wesam, Jane Colmer-Hamood, Hoda Mojazi Amiri, Rishi Raj, and Kenneth Nugent. "Oropharyngeal flora in patients admitted to the medical intensive care unit: clinical factors and acid suppressive therapy." Journal of Medical Microbiology 62, no. 5 (2013): 778–84. http://dx.doi.org/10.1099/jmm.0.053066-0.

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Acid suppression therapy in critically ill patients significantly reduces the incidence of stress ulceration and gastrointestinal (GI) bleeding; however, recent studies suggest that proton pump inhibitors (PPIs) increase the risk of pneumonia. We wanted to test the hypothesis that acid suppressive therapy promotes alteration in the bacterial flora in the GI tract and leads to colonization of the upper airway tract with pathogenic species, potentially forming the biological basis for the observed increased incidence of pneumonia in these patients. This was a prospective observational study on p

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14

Manolis, E., A. Tsakris, D. Kandiloros, et al. "Alterations to the oropharyngeal and nasopharyngeal microbial flora of children after tonsillectomy and adenoidectomy." Journal of Laryngology & Otology 108, no. 9 (1994): 763–67. http://dx.doi.org/10.1017/s0022215100128051.

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AbstractThe oropharyngeal and nasopharyngeal microbial flora of 40 children with chronically hypertrophied and infected tonsils or adenoids, was studied. Twenty of the children were treated by tonsillectomy and 20 by adenoidectomy. Swabs were taken from the surgical field pre-operatively and from the oropharynx or the nasopharynx 10 and 30 days post-operatively. The swabs were cultured on suitable culture media and identification as well as quantitative estimation of the isolated bacteria, was carried out. Most of the potentially pathogenic bacteria exhibited β-lactamase production.Interesting

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15

İMRE YETKİN, Duygu, and Ruhi ONUR. "A DEVASTATING COMPLICATION OF DENTAL EXTRACTION: LEMIERRE’S SYNDROME WITH NECK AND MEDIASTINAL ABSCESS." Kocatepe Tıp Dergisi 24, no. 4 (2021): 514–17. http://dx.doi.org/10.18229/kocatepetip.826881.

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A dental extraction is a frequently performed procedure in daily routine. Fatal infections may occur after dental extraction due to the richness of the oropharyngeal flora from aerobic and anaerobic microorganisms. Oropharyngeal infections can extend into the neck and mediastinum via cervical fascia leading to severe inflammation in soft tissues and vessels with life-threatening complications. We present a patient with complications after dental extraction procedure including severe deep neck inflammation, thrombophlebitis of jugular vein (Lemierre’s syndrome), mediastinal abscess, and empyema

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Reig, Milagro, Juan-Carlos Galan, Fernando Baquero, and Jose Claudio Perez-Diaz. "Macrolide Resistance inPeptostreptococcus spp. Mediated by ermTR: Possible Source of Macrolide-Lincosamide-Streptogramin B Resistance inStreptococcus pyogenes." Antimicrobial Agents and Chemotherapy 45, no. 2 (2001): 630–32. http://dx.doi.org/10.1128/aac.45.2.630-632.2001.

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ABSTRACT Eighty percent (21 of 26) of macrolide-resistantPeptostreptococcus strains studied harbored theermTR gene. This methyltransferase gene is also the most frequently found gene among macrolide-lincosamide-streptogramin B-resistant Streptococcus pyogenes strains. Transfer of theermTR gene from Peptostreptococcus magnus to macrolide-susceptible S. pyogenes strains indicates that this resistance determinant may circulate among gram-positive aerobic and anaerobic species of the oropharyngeal bacterial flora.

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17

Jonkers, D., E. Stobberingh, and R. Stockbrügger. "Influence of oropharyngeal flora and specimen pretreatment on the recovery ofHelicobacter pylori." European Journal of Clinical Microbiology & Infectious Diseases 15, no. 5 (1996): 378–82. http://dx.doi.org/10.1007/bf01690093.

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18

Carlson, David, Elizabeth McKeen, Michael Mitchell, et al. "Oropharyngeal flora in healthy infants: Observations and implications for cystic fibrosis care." Pediatric Pulmonology 44, no. 5 (2009): 497–502. http://dx.doi.org/10.1002/ppul.21029.

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19

Gupta, Mridul, Radhika Annam, Joseph Bahgat, and Margaret Eng. "Porphyromonas asaccharolytica as a Rare Causative Agent for Lemierre’s Syndrome." Case Reports in Infectious Diseases 2018 (November 7, 2018): 1–5. http://dx.doi.org/10.1155/2018/3628395.

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Lemierre’s syndrome is a rare disease associated with significant morbidity and mortality. It begins with an oropharyngeal infection, which spreads locally to involve the internal jugular vein causing thrombophlebitis, followed by distant spread and metastatic infections. Affected individuals are commonly young adults. Causative organisms are usually oropharyngeal flora, most commonly being the anaerobe Fusobacterium necrophorum. Porphyromonas asaccharolytica is a rare etiological agent with only three cases being reported in the literature. This case report describes a previously healthy 22-y

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20

Merete Tesfaye, Wondimu, Simbo Teklu Shiferaw, Chaka Tolossa Eticha, et al. "Oropharyngeal Pathogenic Bacteria: Carriage, Antimicrobial Susceptibility Pattern and Associated Risk Factors among Febrile Patients." International Journal of Pharmaceutical Sciences and Developmental Research 8, no. 1 (2022): 006–12. http://dx.doi.org/10.17352/ijpsdr.000037.

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Background: Pharyngeal and respiratory infections due to bacteria are global concerns especially because of the emergence of multi-drug resistant strains. The Oropharynx is one of the regions of the human body that is heavily colonized by microbial flora. So, the Oropharyngeal carriage is a major risk factor for an invasion and developing the disease. Therefore, this study was aimed at determining the carriage rate of potential pathogenic Oropharyngeal bacteria, associated risk factors, and antimicrobial susceptibility patterns among febrile patients at AHMC. Methods: A Cross-sectional study w

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21

Chaitanya, Pentapati. "A case of cervicofascial actinomycosis presenting as recurrent neck abscess." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 1 (2019): 194. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20195217.

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<p class="abstract">Actinomycosis is a slowly suppurative infection caused by <em>Actinomyces </em>sp. which are gram positive, facultative anaerobic, branching, acid-fast negative bacilli, belonging to the normal flora of the oropharyngeal cavity. Cervicofacial actinomycosis is uncommon. The diagnosis of cervicofacial actinomycosis is also challenging as high index of suspicion is required to clinch the diagnosis. We herein present a case of recurrent paratracheal abscess which was proven to be actinomycosis.</p>

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22

Mehrotra, Rohit, S. P. Agarwal, G. K. Shukla, M. Srivastava, M. Singh, and N. Bhatia. "Effect of radiation on oropharyngeal flora in patients of head and neck cancer." Indian Journal of Otolaryngology and Head & Neck Surgery 49, no. 4 (1997): 344–49. http://dx.doi.org/10.1007/bf02994648.

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23

Mehrotra, Rohit, S. P. Agarwal, G. K. Shukla, N. Bhatia, M. Singh, and M. Srivastava. "Effect of radiation on oropharyngeal flora in patients of head and neck cancer." Indian Journal of Otolaryngology and Head & Neck Surgery 50, no. 4 (1998): 333–37. http://dx.doi.org/10.1007/bf03000683.

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24

Sachs, Alfred P. E., Dirk Van Der Waaij, Klaas H. Groenier, Gerard H. Koëter, and Janette Schiphuis. "Oropharyngeal Flora in Asthma and in Chronic Obstructive Pulmonary Disease: Indigenous Oropharyngeal Microorganisms in Outpatients with Asthma or Chronic Obstructive Pulmonary Disease." American Review of Respiratory Disease 148, no. 5 (1993): 1302–7. http://dx.doi.org/10.1164/ajrccm/148.5.1302.

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Barrs, Vanessa R., Graeme S. Allan, Patricia Martin, Julia A. Beatty, and Richard Malik. "Feline pyothorax: A retrospective study of 27 cases in Australia." Journal of Feline Medicine and Surgery 7, no. 4 (2005): 211–22. http://dx.doi.org/10.1016/j.jfms.2004.12.004.

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Pyothorax was diagnosed in 27 cats between 1983 and 2002. In 21 (78%) of the cases, pleural fluid culture and/or cytology was consistent with a mixed anaerobic bacterial infection of oropharyngeal origin. In six cases (22%), infection was caused by unusual pathogens or pathogens of non-oropharyngeal origin, including a Mycoplasma species, Cryptococcus gattii, Escherichia coli, Salmonella typhimurium and Staphylococcus aureus. The overall mortality rate was 22%. Treatment was successful in 18 of 19 cases (95%) where closed thoracostomy tubes were inserted. One case resolved only after thoracoto

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Pardo-Pol, Albert, Daniel Pérez-Prieto, Albert Alier, et al. "Acute Hematogenous Periprosthetic Hip Infection by Gemella morbillorum, Successfully Treated with Debridement, Antibiotics and Implant Retention: A Case Report and Literature Review of Osteoarticular Gemella morbillorum Infections." Tropical Medicine and Infectious Disease 7, no. 8 (2022): 191. http://dx.doi.org/10.3390/tropicalmed7080191.

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Gemella morbillorum is a facultative anaerobic, catalase-negative and non-spore forming Gram-positive cocci. It can be found as part of the normal oropharyngeal flora, in the gastrointestinal tract and the female genital tract. However, it can be a causal agent of infections such as endocarditis, meningitis or brain abscesses, and very rarely can cause osteoarticular infections. Herein, a case report of an acute hematogenous prosthetic hip infection caused by Gemella morbillorum, successfully treated with a DAIR and beta-lactam antibiotic therapy, is presented. We provide a literature review o

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27

Aygun, Deniz, Beste Akdeniz, Gokhan Aygun, Haluk Cokugras, and Yıldız Camcıoglu. "Thyroid abscess due to Eikenella corrodens in a pediatric patient." Journal of Infection in Developing Countries 13, no. 10 (2019): 945–47. http://dx.doi.org/10.3855/jidc.11057.

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Eikenella corrodens is one of the HACEK bacteria that is commensal microorganism of the oropharngeal flora. E. corrodens has been increasingly reported to cause pyogenic abscesses, especially in diabetic or immunocompromised adults. It is less frequently reported in immunocompotent children. Here, we report a deep neck infection, including the thyroid gland, in a previously healthy girl. E. corrodens was the only microorganism isolated in two different cultures. Antibiotic susceptibility is variable, in contrast to other oropharyngeal pathogens. Thus, to avoid delayed treatment, E. corrodens s

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Maurya, Reeta, Madhup Rastogi, Manodeep Sen, Ajai Kumar Singh, and Somali Sanyal. "Effect of Chemo-radiotherapy on Salivary Flora of Oral Cancer Patients." Journal of Pure and Applied Microbiology 15, no. 3 (2021): 1501–7. http://dx.doi.org/10.22207/jpam.15.3.44.

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Management of cancers of oral cancers has remained a major challenge in India and globally. Radiotherapy and chemotherapy are mostly employed for treatment which inflicts changes in oral mucosa and makes it vulnerable for bacterial colonization and eventual infections. This study aims at evaluating the changes in oropharyngeal flora (bacteria and yeast) in oral cancer patients treated by a combination of chemo-radiotherapy with the control groups comprising of non-cancerous patients living in the same environment. This prospective evaluation included Seventy-seven patients with oral squamous c

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Ozuguz, Pınar, Elif E. Callioglu, Kamil G. Tulaci, et al. "Evaluation of nasal and oropharyngeal flora in patients with acne vulgaris according to treatment options." International Journal of Dermatology 53, no. 11 (2014): 1404–8. http://dx.doi.org/10.1111/ijd.12537.

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Etherton-Beer, Christopher D., Tim Inglis, and Grant Waterer. "Prevalence of oropharyngeal antibiotic-resistant flora among residents of aged care facilities: a pilot study." Respirology 20, no. 7 (2015): 1139–41. http://dx.doi.org/10.1111/resp.12545.

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31

Stoll, P., H. Huber, K. Pelz, and D. Weingart. "Antimicrobial Effects of the Tetrachlorodecaoxygen-Anion Complex on Oropharyngeal Bacterial Flora: An in vitro Study." Chemotherapy 39, no. 1 (1993): 40–47. http://dx.doi.org/10.1159/000238972.

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Pirrone, Alessandro, Carolina Castagnetti, Jole Mariella, et al. "Yeast Flora in Oropharyngeal and Rectal Mucous Membranes of Healthy and Critically Ill Neonatal Foals." Journal of Equine Veterinary Science 32, no. 2 (2012): 93–98. http://dx.doi.org/10.1016/j.jevs.2011.06.013.

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Exner, M., G. Gregori, H. W. Pau, and F. Vogel. "In vivo studies on the microbicidal activity of antiseptics on the flora of the oropharyngeal cavity." Journal of Hospital Infection 6 (March 1985): 185–88. http://dx.doi.org/10.1016/s0195-6701(85)80066-9.

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Murdoch, D. A., S. Gibbs, S. Easmon, J. Franklin, T. A. Lister, and S. Tabaqchali. "Effect of ceftazidime and gentamicin on the oropharyngeal and faecal flora of patients with haematological malignancies." Journal of Antimicrobial Chemotherapy 26, no. 3 (1990): 419–28. http://dx.doi.org/10.1093/jac/26.3.419.

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35

Gorris, F., S. Faut, S. Daminet, H. De Rooster, J. H. Saunders, and D. Paepe. "Pyothorax in cats and dogs." Vlaams Diergeneeskundig Tijdschrift 86, no. 3 (2017): 183–97. http://dx.doi.org/10.21825/vdt.v86i3.16288.

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Pyothorax, or thoracic empyema, is an infection of the pleural space, characterized by the accumulation of purulent exudate. It is a life-threatening emergency in dogs as well as in cats, with a guarded prognosis. Dyspnea and/or tachypnea, anorexia and lethargy are the most typical clinical signs. Diagnosis is usually straightforward, based on the clinical symptoms combined with pleural fluid analysis, including cytology and bacterial culture. Most commonly, oropharyngeal flora is isolated in the pleural fluid. Treatment can be medical or surgical, but needs to be immediate and aggressive. In

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Rossella, Parrinello, Carità Patrizia, Triolo Fabio Oreste, et al. "Native Mitral Valve Endocarditis Caused byNeisseria elongatasubsp.nitroreducensin a Patient with Marfan Syndrome: First Case in Italy and Review of the Literature." Case Reports in Infectious Diseases 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/4956205.

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Neisseria elongata(NE) is an aerobic Gram-negative organism that constitutes part of the commensal human normal oropharyngeal flora. Although previously considered not to be pathogenic, it has been recognized as an occasional cause of significant infections in humans. We report here the first case in Italy of infective endocarditis of a native prolapsing mitral valve in a patient with Marfan syndrome, caused by NE subspeciesnitroreducenswhich has been rarely isolated from clinical specimens. The culprit organism has been confirmed by mass spectrometry directly from the positive blood culture,

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Amin, M., A. Bakhtiar, M. Subarjo, et al. "Screening for Middle East respiratory syndrome coronavirus among febrile Indonesian Hajj pilgrims: A study on 28,197 returning pilgrims." Journal of Infection Prevention 19, no. 5 (2018): 236–39. http://dx.doi.org/10.1177/1757177418765634.

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There were 211,000 Indonesian Hajj pilgrims going to Mecca through 11 main airports in 2015 who were at risk of contracting the Middle East respiratory syndrome coronavirus (MERS-CoV). We aimed to find out whether there was any occurrence of MERS-CoV by performing screening on 28,197 returning pilgrims. Those with a body temperature of > 38 °C and respiratory symptoms were sent to the airport clinic to have an oropharyngeal swab and a bacterial culture. Fifteen pilgrims had fever (> 38 °C) accompanied by respiratory symptoms; of these, 12 patients were diagnosed with upper and lower resp

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P.M, Hippargekar. "Lemiere's Syndrome Caused by Klebsiella Oxytoca; A Case Report." International Journal of Medical and Pharmaceutical Research 4, no. 3 (2023): 10–13. https://doi.org/10.5281/zenodo.8087439.

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Lemiere’s syndrome is a rare but life-threatening condition which is most often preceded by an oropharyngeal infection. The most common organism involved is fusobacterium necrophorum, which is a part of normal flora of oropharynx. This case report describes a rare case of Klebsiella oxytoca associated Lemiere’s syndrome in a patient with poorly controlled Diabetes Mellitus. To our knowledge there has been only one single reported case of Lemiere’s syndrome caused by Klebsiella Oxytoca and this should be considered among the possible organism causing Lemiere’s syndrome.

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Shen, Yijun, Ling Dai, Yanwen Zhu, and Yishu Lang. "The Impact of Improved Oral Care Methods on the Oral Health of Patients Undergoing Transoral Mechanical Ventilation." Computational and Mathematical Methods in Medicine 2022 (September 16, 2022): 1–7. http://dx.doi.org/10.1155/2022/7596654.

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Objective. To explore the effects of improved oral care on the number of oropharyngeal bacteria and the incidence of ventilator-associated pneumonia in patients undergoing mechanical ventilation through oral endotracheal intubation by improving conventional oral care methods and operating procedures and to evaluate the quality of improved oral care and effect. Methods. A total of 100 cases of mechanically ventilated patients with oral endotracheal intubation who met the inclusion criteria were randomly divided into the observation group and control group with 50 cases each. The control group t

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Pedreira, Mavilde L. G., Denise M. Kusahara, Werther Brunow de Carvalho, Silvia Cristina Núñez, and Maria Angélica S. Peterlini. "Oral Care Interventions and Oropharyngeal Colonization in Children Receiving Mechanical Ventilation." American Journal of Critical Care 18, no. 4 (2009): 319–28. http://dx.doi.org/10.4037/ajcc2009121.

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Background Recent progress in identification of oral microorganisms has shown that the oropharynx can be a site of origin for dissemination of pathogenic organisms to distant body sites, such as the lungs.Objective To compare the oropharyngeal microbiological profile, duration of mechanical ventilation, and length of stay in the intensive care unit of children receiving mechanical ventilation who had pharmacological or nonpharmacological oral care.Methods A randomized and controlled study was performed in a pediatric intensive unit in São Paulo, Brazil. A total of 56 children were randomly as

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Jung, Da Hwi, Dong Hoon Baek, Jin A. Yoon, et al. "Concordance between Oropharyngeal Flora and Peristomal Wound Culture Bacteria Following Percutaneous Endoscopic Gastrostomy: A Prospective Cohort Study." Journal of the Korean Dysphagia Society 11, no. 1 (2021): 35–42. http://dx.doi.org/10.34160/jkds.2021.11.1.005.

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Heald, Alison E., Gary M. Cox, Wiley A. Schell, John A. Bartlett, and John r. Perfect. "Oropharyngeal yeast flora and fluconazole resistance in HIV-infected patientsreceiving long-term continuous versus intermitent fluconazole therapy." AIDS 10, no. 3 (1996): 263–68. http://dx.doi.org/10.1097/00002030-199603000-00004.

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Chang, Nicholas, James McKee, and Valerie Marmolejo. "Necrotizing Fasciitis due to Streptococcus constellatus in a Patient with Uncontrolled Diabetes and Bilateral Diabetic Foot Ulceration." Wounds: a compendium of clinical research and practice 35, no. 2 (2023): e74-e77. http://dx.doi.org/10.25270/wnds/22044.

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Introduction. Streptococcus constellatus is commensal flora of the oropharyngeal, gastrointestinal, and genitourinary tracts with a proclivity for abscess formation. Bacteremia due to S constellatus is rare; however, rising incidences have been reported, particularly in patients with diabetes. Prompt surgical debridement and antibiotic therapy with a cephalosporin are the mainstays of treatment. Case Report. The case presented here involves a patient with poorly controlled diabetes who had necrotizing soft tissue infection secondary to S constellatus. The infection originated from bilateral di

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Donowitz, Leigh G., M. Carol Page, Betty Lou Mileur, and Sharon H. Guenthner. "Alteration of Normal Gastric Flora in Critical Care Patients Receiving Antacid and Cimetidine Therapy." Infection Control 7, no. 1 (1986): 23–26. http://dx.doi.org/10.1017/s0195941700063748.

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AbstractOne hundred fifty-three critical care patients with documented cimetidine and antacid use were prospectively studied with serial gastric pH determinations and semiquantitative gastric fluid cultures. This study documents the abnormal gastric colonization of patients with therapeutically altered gastric acidity by hospital acquired gram negative rods (GNR). Three hundred twenty-four gastric fluid cultures from 153 patients revealed 152 (47%) positive cultures for GNR, 78 (24%) sterile specimens, and 94 (29%) positive for mixed oropharyngeal flora. One hundred forty (59%) of the 236 cult

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Zhang, Allison N., Debra Guss, and Smruti R. Mohanty. "Esophageal Stricture Caused by Actinomyces in a Patient with No Apparent Predisposing Factors." Case Reports in Gastrointestinal Medicine 2019 (January 2, 2019): 1–4. http://dx.doi.org/10.1155/2019/7182976.

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Actinomyces species are Gram positive anaerobic or microaerophilic bacteria that are part of the human flora in the oropharyngeal, gastrointestinal, and genitourinary tract. In the presence of a mucosal injury, they can become pathogenic and infect the underlying tissue without respect for tissue planes, leading to abscesses, fistulas, and sinus tracts. Through contiguous and hematogenous spread, virtually any organ can become infected. The presentation can be myriad and often mimics tumors, tuberculosis, or other more common infections and inflammatory conditions. While the cervicofacial regi

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Almirall, Jordi, Ramon Boixeda, Mari C. de la Torre, and Antoni Torres. "Epidemiology and Pathogenesis of Aspiration Pneumonia." Seminars in Respiratory and Critical Care Medicine 45, no. 06 (2024): 621–25. http://dx.doi.org/10.1055/s-0044-1793907.

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AbstractAspiration pneumonia (AP) remains a critical health issue, especially among older and hospitalized patients. This review focuses on understanding the epidemiology and pathogenesis of AP, exploring key risk factors, and proposing diagnostic strategies. Aspiration pneumonia is commonly associated with hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), where pathogens introduced into the lungs from gastric aspiration cause infection. Several factors, such as oropharyngeal dysphagia, silent aspiration, and poor oral health, contribute to increased risk, especially

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Talapko, Jasminka, Martina Juzbašić, Tatjana Matijević, et al. "Candida albicans—The Virulence Factors and Clinical Manifestations of Infection." Journal of Fungi 7, no. 2 (2021): 79. http://dx.doi.org/10.3390/jof7020079.

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Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity, gastrointestinal and vaginal tract, and healthy individuals’ skin. In 50% of the population, C. albicans is part of the normal flora of the microbiota. The various clinical manifestations of Candida species range from localized, superficial mucocutaneous disorders to invasive diseases that involve multiple organ systems and are life-threatening. From systemic and local to hereditary and environmental, diverse factors lead to disturbances in Candida’s normal homeostasis, resulting in a transition from normal

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Watkins, Rhys, Carl Marincowitz, Thomas Locke, and Steven Hunter. "An Unusual cause of Endocarditis." BMJ Case Reports 15, no. 12 (2022): e249214. http://dx.doi.org/10.1136/bcr-2022-249214.

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A man in his 20s attended the emergency department with three days of fever, headache, reduced appetite and a sore throat. COVID-19 point-of-care test was negative. Blood cultures grew a gram-negative coccobacillus,Neisseria elongata. Following an episode of confusion, MRI head revealed septic emboli. Prolapse of the mitral valve with regurgitation was noted on echocardiography. Infection was found to have originated from multiple dental caries and treatment required a combination of dental extraction, prolonged antibiotic therapy and surgery for mitral valve repair.N. elongatais part of the n

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Pham, Kim, Satish Kalanjeri, and Jeremy Johnson. "Perplexing pneumonia: Pasteurella lung infection." BMJ Case Reports 18, no. 6 (2025): e263697. https://doi.org/10.1136/bcr-2024-263697.

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Pasteurella multocida,commonly found in the oropharyngeal flora of cats and dogs, typically causes soft tissue infections following animal bites or scratches. Respiratory infections due toPasteurellaare rare and usually occur in individuals with predisposing factors, such as chronic lung disease or immunosuppression. We present an unusual case of an elderly male who developed aPasteurellalung infection after his cat licked his dentures. The patient, with no significant history of lung disease or immunosuppression, presented with fever, cough and dyspnoea. The diagnosis was confirmed via bronch

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Johnson, James Harvey, and Patricia A. Benson. "Laboratory reference values for a group of captive Ball Pythons (Python regius)." American Journal of Veterinary Research 57, no. 9 (1996): 1304–7. http://dx.doi.org/10.2460/ajvr.1996.57.09.1304.

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Abstract Objective Laboratory reference values, including hematologic and serum biochemical variables, and oropharyngeal bacteria flora, were determined in a group of captive Ball Pythons (Python regius). Animals 20 adult Ball Pythons, weighing between 700 and 1,510 g, were allowed to acclimate at the recommended temperature range for the species (25 C nighttime, up to 30 C daytime), then were evaluated for internal parasites and treated with appropriate medication prior to the start of the study. Procedure Hematologic values determined included WBC, hemoglobin, hematocrit, plasma protein, and

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