Academic literature on the topic 'Orphan'

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Journal articles on the topic "Orphan"

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Asif, Rashna, Tahira Gilani, Mateen Iqbal, and Muhammad Imran. "Breaking the Silence: A Quantitative Analysis of Challenges among Orphaned Children in Sargodha District Orphanages." Journal of Education and Social Studies 5, no. 1 (March 31, 2024): 168–75. http://dx.doi.org/10.52223/jess.2024.5116.

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Orphans represent a significant population worldwide, and orphan homes are responsible for providing support for holistic development in the lives of children. The purpose of the study was to investigate the psychological, social, and educational challenges faced by orphan children in orphan homes. The theoretical framework of the current study was based on the Attachment Theory by Bowlby, which states how early caregiver relationships influence the psychological, social, and educational development of orphan children in orphan homes. All of the orphan children in SOS Children Village district Sargodha made up the population of the current study. A sample of 206 orphan children was selected randomly from SOS Children Village district Sargodha. Reliable data were gathered using a quantitative survey study design, and the instrument's reliability was confirmed by Cronbach's Alpha, which was found to be 0.89. The obtained data were analyzed using descriptive statistics such as mean, standard deviations, frequency percentages, and inferential statistics, for instance, the t-test. The results showed that gender was found to be significant regarding psychological, social, and educational challenges. In addition, female orphan children have a greater mean score as compared to males concerning psychological and social challenges. While, concerning educational challenges male orphans have a greater mean score as compared to female orphan children. However, to overcome these challenges it is suggested that it is essential to create efficient programs that can recognize and tackle the emotional, social, and academic difficulties orphaned children confront.
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Ali, Dr Umar Mohammed. "IMPORTANT OF TAKEN CARE OF ORPHANS IN ISLAMIC RELIGION PERSPECTIVE." American Journal of Interdisciplinary Innovations and Research 5, no. 7 (July 1, 2023): 5–12. http://dx.doi.org/10.37547/tajiir/volume05issue07-02.

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If an orphan possesses wealth in any form, Allah commands the community or orphan guardian to use it judiciously in their benefit, conserve it for them, multiply it for them, if possible, and turn it over to them when they come of age , prophet Muhammad SAW (PBUH) spoke several times on the issues of the Orphats , who ever take care of the Orphats here in this world , Allah SWT will put him in to Paradise . This research is focus on the important of taken care of the Orphats in a Islamic religion perspective , orphans actually have the right to be taken care of. But with every right comes responsibility, and the Quran places this responsibility on the individual, meaning every Muslim should give to orphans in need.
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Yousuf, Sundus, and Bushra Khan. "Challenges Faced By Women Orphans’ Caregivers: A Qualitative Study." Pakistan Journal of Gender Studies 15, no. 1 (September 8, 2017): 213–28. http://dx.doi.org/10.46568/pjgs.v15i1.136.

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Wellbeing of an orphan caregiver affects the child-rearing practice, which in turn could affect the growth and development of the orphaned child. Challenges faced by women orphan caregivers make caring a more extraneous task. A qualitative study was designed, to investigate the challenges faced by women orphan caregivers. Data was collected from SOS children village, an internationally recognized orphanage located in Karachi, Pakistan. An open ended interview was conducted with 17 women orphan caregivers employed at the organization through interview schedule. Various themes were identified. Two major themes indicating challenges were identified; professional or organizational level and personal level that were further divided in sub themes and analyzed. Results indicated that caregivers themselves were abandoned and suffered from psychological disturbances and lacked in awareness of effective coping skills. Orphan caregivers faced distress due to inability to effectively handle hectic routine at the orphanage, low salary, and lack of knowledge and skill to address diverse needs of all children. Overall, caring for orphans is a challenging job and it is recommended that orphan caregivers are provided with professional support to cope with psychological issues; and training on caregiving knowledge and skills to effectively handle children with diverse needs. This could eventually help in improving wellbeing of the caregivers and enhancing overall development of the orphans.
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Alkurd, Deea Ahmed. "A Proposed Vision To Strengthen The Psychological And Social Support For Orphans In Care Homes." Al-Lughah: Jurnal Bahasa 10, no. 1 (June 23, 2021): 65. http://dx.doi.org/10.29300/lughah.v10i1.4557.

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The study aimed to identify the necessity of building a proposed vision to enhance the psychological and social support of orphans in care homes, and the researcher reviews in this study the definition of the study terms represented in psychological and social support and orphanages and care homes, as well as the difficulties and challenges facing orphan care institutions in providing psychological and social support to orphans The researcher used the descriptive desktop approach to identify the literature related to developing the proposed vision to enhance psychological and social support for orphans in care homes. The study showed that providing psychological and social support helps orphans Depositors in care homes to face life stresses and positive adaptation to the circumstance of loss and overcome difficulties before them in order to develop their psychological and social compatibility, as well as enable them through programs to explore their capabilities and develop their capabilities and raise their competencies. The study recommended providing orphan care institutions with the amenities, entertainment and educational games aimed at contributing to creating a positive atmosphere aimed at achieving psychological and social compatibility for the orphans in which they are placed1. Ibrahim, Zakaria (1973 AD) The Artist and the Man, Egypt: Dar Gharib for Printing and Publishing.2. Istiti, Tasnim, Muhammad Jamal. Hassan (2007 CE): Orphan's Rights in Islamic Jurisprudence, Master Thesis, College of Graduate Studies, An-Najah National University, Nablus, Palestine.3. Al-Buraq, Amna (2011): The needs of adults of unknown parentage after leaving institutions for orphans, the first Saudi conference for orphan care.4. Jalal, Nusseibeh (2017): Psychological care for Syrian refugee orphans, "a field study", Research Center for Studies, Syria.5. Al-Halibi, Khalid bin Saud (1425 AH): How can you contribute to developing the positive character of an orphan by making use of educational experiences, a working paper in a symposium entitled: “Future visions for orphan care in the Kingdom of Saudi Arabia,” Ministry of Social Affairs, Ministry Agency For Social Affairs, Social Affairs Office, Dammam, Tuesday 21/8/1425 AH corresponding to 5/10/20046. Hamzah, Ahmad (2011): The Effectiveness of an Integrated Counseling Program in Reducing Violence for a Sample of Orphaned Delinquent Children, The First Saudi Conference for Orphan Care.7. Al-Khayyat, Abdul Aziz (1981): Interdependent Society in Islam, 2nd Edition, Al-Risalah Foundation, AmmanAl-Sadhan, Abdullah bin Nasser (2001); Children without families, Obeikan Library, Riyadh.9. Al-Sulami, Musleh Salih (1415 AH), raising orphans in the Kingdom of Saudi Arabia, an evaluation study, an unpublished master's thesis, Department of Islamic Education, College of Education, Umm Al-Qura University, Makkah Al-Mukarramah.10. Al-Suwairi, Ali Abdullah; (2009 AD); “Psychological and Social Problems among Orphans in the Charitable Society of Makkah Al-Mukarramah”, Master Thesis, College of Education, Department of Psychology, Umm Al-Qura University, Makkah Al-Mukarramah.11. Amer, Adel (2004 AD); Orphan children have no legal and legal protection, a study published (in :) The House of Legal, Islamic and Human Sciences Forum, http://adel-amer.catsh.12. Al-Anani, Hanan Abdel-Hamid (2005): Development of Social, Religious and Ethical Concepts in Early Childhood, Jordan: House of Fikr.13. Al-Matrafi, Fawzia Muhammad Abdel Mohsen; (2001): “Study of the relationship between the nutritional status and meals provided to children of orphanages in Makkah Al-Mukarramah region for school-age children (12-6 years old)”, PhD Thesis, College of Education for Home Economics, Department of Nutrition and Food Sciences, Makkah Al-Mukarramah.14. Al-Nuwaiser, Khalid bin Abdulaziz, (2011): The role of national systems in protecting and caring for orphans' rights, The First Saudi Conference for Orphan Care.15. Browne, K. (2009). The Risk of Harm to Young Children in Institutional Care. Typeset by Grasshopper Design Company. Printed by Stephen Austin & Sons Ltd.16. Carter R. (2005). Family Matters: A study of institutional childcare in Central and Eastern Europe and the Former Soviet Union. London:Everychild.
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Zhao, Qi, Hui He, Huang Gu, Junfeng Zhao, Peilian Chi, and Xiaoming Li. "Facial Expression Processing of Children Orphaned by Parental HIV/AIDS: A Cross-Sectional ERP Study with Rapid Serial Visual Presentation." International Journal of Environmental Research and Public Health 18, no. 19 (September 23, 2021): 9995. http://dx.doi.org/10.3390/ijerph18199995.

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Existing behavioral studies have suggested that individuals with early life stress usually show abnormal emotional processing. However, limited event-related brain potentials (ERPs) evidence was available to explore the emotional processes in children orphaned by parental HIV/AIDS (“AIDS orphans”). The current study aims to investigate whether there are behavioral and neurological obstacles in the recognition of emotional faces in AIDS orphans and also to further explore the processing stage at which the difference in facial emotion recognition exists. A total of 81 AIDS orphans and 60 non-orphan children were recruited through the local communities and school systems in Henan, China. Participants completed a computer version of the rapid serial visual presentation (RSVP) task while recording ERPs. Behavioral results showed that orphans displayed higher response accuracy and shorter reaction time than the control (ps < 0.05). As for the ERPs analysis, the attenuated amplitude of N170 (i.e., an early component sensitive to facial configuration) was observed in AIDS orphans compared to the non-orphan control with happy and neutral faces; P300 (i.e., an endogenous component for affective valence evaluation in emotional processing) also showed significant differences in parietal lobe between groups, the non-orphan control group produced larger P300 amplitudes than orphans (p < 0.05). The results suggested that compared to the control group, AIDS orphans showed impaired facial emotion recognition ability with reduced brain activation.
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Afuan, Lasmedi, Swahesti Puspita Rahayu, Bekti Afif Ginanjar, Nurul Hidayat, and Ipung Permadi. "Information System for Orphan Data Management in Karangsari Village, Kalimanah District, Purbalingga Regency." E3S Web of Conferences 448 (2023): 02027. http://dx.doi.org/10.1051/e3sconf/202344802027.

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An orphan is a term used to refer to someone who has been left by their parents while still underage. Providing support for orphans is a commendable activity. Supporting orphans has many virtues, as stated in the following Hadith: Narrated by Abu Ya'la and Thobrani, Shahih At Targhib Al Albani: "Whoever includes an orphan among two Muslim parents in their meals and drinks, providing for their needs, will surely enter Paradise.". The first step in supporting orphans is to find them. Searching for orphan data is difficult to accomplish if we rely solely on manual data collection. Sometimes the obtained data does not match the desired requirements. To help facilitate this step, an information system for managing orphan data is created. The aim is to simplify the management of orphan data and assist the community in searching for orphan data. The development of this orphan data management information system utilizes the waterfall method, which includes the stages of analysis, design, implementation, testing, and maintenance using the Laravel framework. The result of this research is a web-based information system for managing orphan data, with a case study in Karangsari Village, Kalimanah, Purbalingga Regency.
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Aqeel, Muhammad, Rafia Komal, and Tanvir Akhtar. "Emotional empathy mediates the relationship between personality traits and coping strategies in orphan and non-orphan students." International Journal of Human Rights in Healthcare 12, no. 2 (May 7, 2019): 163–76. http://dx.doi.org/10.1108/ijhrh-02-2018-0015.

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Purpose The purpose of this paper is to inspect the potential mediation pathways among emotional empathy, personality traits and coping strategies in orphan and non-orphan students. Additionally, it designed to investigate the association of coping strategies with emotional empathy and personality traits. Design/methodology/approach Purposive sampling technique and cross-sectional design were employed in current study. The data of 130 adolescents (institutionalized orphans, n= 62; school students, n=68) were included from different high schools and orphanages of Rawalpindi and Islamabad, Pakistan, in 2017. Three instruments, emotional empathy scale (Mehrabian and Epstein, 1972; Shazia, 2004), coping of problem experience (Carver, 1989; Akhtar, 2005), and Eysenck personality questionnaire (Naqvi and Kamal, 2010; Eysenck, 1964; Eysenck and Eysenck, 1994), were employed to measure personality traits, emotional empathy and coping strategies in orphan and non-orphan students. Findings Mediation analyses illustrated that personality traits relegated active avoidance coping strategy through emotional empathy in orphan students. On contrary, the study findings demonstrated that neurotic personality promoted positive coping strategy through emotional empathy in non-orphan students. Research limitations/implications The methodological limitations of this study are that the sample is of 130 participants that limits the generalizability of its results; furthermore, it was done on only the male orphans students of only one institute. Further research can be done on different orphanages to enhance the generalizability of results. This study included orphan and non-orphan students from the two cities of Pakistan; consequently, its findings may not be generalizable to the whole population. In the future, cross-sectional and experimental researches working with more assorted data could help elucidate the mechanisms by which interpersonal factors affect and stimulate coping strategies in orphans and high school students. Practical implications This paper exposes a number of ways for upcoming future studies. This study findings can be employed to enhance knowledge and offer assistance for orphans, on how to identify and get help from coping resources to tackle various problems and how to build new psychological preventions and interventions strategies in the Pakistani society. There still exists a need to find out the effect of emotion, empathy on personality types in relation to different environmental conditions. The findings have implications for pedagogical intervention as such improvements can be initiated in the pedagogical context. Social implications This study comprised only orphan and non-orphan students from two twin cities of Pakistan; consequently, its findings may not be applicable to the whole population. In future, cross-sectional and experimental researches with more assorted data will assist clarify the mechanism that interpersonal factors affect and stimulate coping strategies in high school students. Originality/value Study findings proposed that coping strategies can be promoted by interpersonal factors such as personality traits and empathy to tackle different orphan’s psychological problem in various negative situation.
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Alvi, Sajid Mahmood, Ayla Khan, Mazhar Iqbal Bhatti, and Kainat Younis. "EFFECT OF ANGER EXPRESSION ON MENTAL WELLBEING AND EMOTIONAL EXPRESSIVITY OF ORPHANS AND NON-ORPHANS." Pakistan Journal of Physiology 18, no. 2 (June 30, 2022): 62–65. http://dx.doi.org/10.69656/pjp.v18i2.1425.

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Background: Orphan-hood is a stage that includes numerous mental and emotional problems. Lack of control on emotions puts orphans at risk of uneasiness. The aim of this study was to see the relationship between anger expressions on mental wellbeing and emotional expressions of orphans and non-orphans. Methods: This was a cross-sectional survey conducted from April to June 2021. Data were collected from the orphan and non-orphan adolescent students aged 13–19 years, studying in different institutes of Haripur, Pakistan. After informed consent, State Trait Anger Expression Inventory (STAXI), Short Warwick Edinburg Well-being Scale (SWEMWBS), and Emotional expressivity questionnaires were self-administered by authors and analysed on SPSS-20. Result: Sample size was 200 orphan and non-orphan adolescent students, with equal proportion of males and females. Anger expression was positively linked with emotional expressivity (r=0.29, p<0.001), and anger expression was negatively linked with mental wellbeing (r= -0.45, p<0.001). Orphan students scored high on anger expression (27.62±5.4) and emotional expressivity (55.28±5.79) as compare to non-orphans (23.59±5.79 and 53.31±5.99 respectively). Conclusion: Anger expression is positively linked with emotional expressivity and negatively linked with mental wellbeing. Girls are shyer to express their feelings compared to boys. Boys are more engaged in verbal and physical aggression than girls. Orphan boys show more aggression because they face a lot of adjustment and many other difficulties in institutions. Pak J Physiol 2022;18(2):62–5
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Sajjan, Santosh B. "A Comparative Study to Assess the Quality of Life and Stress among Orphan and Non-orphan Children in Selected Areas of Bagalkot." Indian Journal of Holistic Nursing 11, no. 04 (December 30, 2020): 19–25. http://dx.doi.org/10.24321/2348.2133.202007.

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Introduction: The word orphan comes from the Greek word ‘Orfanos’ and refers to a child permanently bereaved of or abandoned by his or her parents. Methods: A non-experimental descriptive comparative design has been adopted for the present study. The sample of the present study comprises orphan children residing in an orphanage and non-orphan children residing in selected areas of Bagalkot. The sample comprised 30 orphans and 30 non-orphans aged between 10 and 16 years. The data were collected by using self-report, structured closed-ended questionnaires for socio-demographic variables of children, self-administered WHO Quality of life BREF scale, and PSS stress scale. The data obtained were analysed with the help of descriptive and inferential statistics. Result: Findings related to the comparison between the level of stress among the orphan and non-orphan children revealed that majority of orphan children (76.66%) had about moderate stress, 23.33% of the orphan children had high stress, and none of the children had a low level of stress, whereas among non-orphan children, majority (90%) had moderate stress, 10% had low level stress, and none of them had high level stress. The findings related to the comparison of levels of quality of life among the orphan and non-orphan children reveal that a high percentage of orphan children (66.66%) had a moderate quality of life and some of them (33.33%) had a poor quality of life, whereas a high number of non-orphan children (66.66%) had a very good quality of life and some (33.33%) had a good quality of life. No significant association was found between the quality of life and stress scores with the socio-demographic variables of orphan and non-orphan children. Conclusion: The study concluded that orphan children need to improve their quality of life and decrease their level of stress.
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Islam, Mohammad Shamsal, Fazle Siddique M. Yahya, M. Mahfuz Ashraf, and Mohammad Iqbal Hossain. "Hygiene behaviors and nutritional status of children living in orphanages in Bangladesh." International Journal Of Community Medicine And Public Health 10, no. 6 (May 31, 2023): 2010–14. http://dx.doi.org/10.18203/2394-6040.ijcmph20231675.

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Background: Malnutrition is considered a complicated public health issue and depends on multiple factors. Hygienic behavior is related to orphan children’s growth, nutritional outcomes, and sound health. The study’s aim was to assess the hygiene behaviors and nutritional status of orphan students in Bangladesh. Methods: A descriptive cross-sectional quantitative study was conducted in three orphanage centers. A total of 120 respondents were interviewed. A descriptive analysis of the collected data was performed. Results: The monthly mean and median expenditure of orphans was 2000±475 BDT (20$). The number of toilets and waiting time for the orphan to use them are closely associated (χ2= 33.38; Cramer’s V=0.44, df=13; Sig; p<0.001). On average, an orphan waits 32.20 minutes to use the toilet facility when they need it. Orphan family income and disposal of waste in the toilet of the orphan center are strongly associated (χ2=99.19; Cramer’s V=0.49, df=39; Sig; p<0.001). There was a significant association between attending toilet-related hygiene and types of diseases. Hair fall, muscle wasting, fever, and xerosis of the skin were common diseases among orphans. Types of diseases orphans and schedule for the dietary chart are strongly associated (χ2=23.35; Cramer’s V=0.37, df=24; Sig; p<0.001). Conclusions: Integrated approach is required to counter the extent of malnutrition among orphans. Teachers of orphanages should receive proper training so that they are able to take care of the physical and mental health of the orphan children.
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Dissertations / Theses on the topic "Orphan"

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Liyanage, Tharika. "Adopting an orphan biomarker." Thesis, https://vimeo.com/showcase/8930173/video/632499667, 2021. http://hdl.handle.net/1885/251900.

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Marchese, Adriano. "Orphan G protein-coupled receptors." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq41468.pdf.

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Ewers, Susann. "Charakterisierung des Orphan-Chemokinrezeptors HCR." [S.l. : s.n.], 2006. http://nbn-resolving.de/urn:nbn:de:bsz:25-opus-50565.

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Freiburg i. Br., Univ., Diss., 2008.
Aus: TN Hartmann, M Leick, S Ewers, A Diefenbacher, I Schraufstetter, M Honczarenko and Meike Burger (2008) Human B cells express the orphan chemokine receptor CRAM-A/B in a maturation-stage-dependent and CCL5-modulated manner. Immunology April 2008.
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Ho, M. T. B. "Pharmacology of the orphan opioid receptor." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604104.

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The neuropeptide nociceptin/orphanin FQ (OFQ) was recently identified as the endogenous agonist of the orphan opioid receptor ORL1. In this thesis pharmacological studies on the ORL1 receptor were advanced by the comparison of the potencies and efficacies of several ligands at the rat ORL1 receptor stably transfected into chinese hamster ovary (CHO) cells, with those at the native receptor in the central (frontal cortex) and peripheral (anococcygeus muscle) nervous systems. Most notably, the work involved a close examination of the pharmacology of the first selective non-peptide antagonist for the ORL1 receptor, J-113397, and in this case the work extended to the use of in-vivo techniques measuring effects on locomotor activity and food consumption. The work on the pharmacology of the ORL1 receptor in the anococcygeus followed our discovery of the presence of the receptor in this tissue. Under conditions where electrical-field stimulation produced a selective activation of the sympathetic nerves, nociceptin/OFQ fully inhibited the pure adrenergic motor response. The hexapeptides Ac-RYYRWK-NH2 (RWK) and Ac-RYYRIK-NH2 (RIK) were potent partial-agonists whereas [Phe1ψ(CH2-NH)Gly2]nociceptin(1-13)NH2 (FGNC13) and J-113397 had little or no efficacy and were competitive antagonists. This thesis reflects on the various pharmacological actions of nociceptin/OFQ, concentrating on establishing discriminatory effects for selected compounds and possible functional role of the ORL1 receptor in the brain.
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Sniehotta, Maike. "Signaltransduktionsmechanismen in Orphan-Rezeptor-transfizierten CHO-Zellen." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968891977.

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Johansson, Lotta. "Studies on the atypical orphan receptor SHP /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-071-7/.

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Arkenbout, Elisabeth Karin. "TR3 nuclear orphan receptor in cardiovascular disease." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/77443.

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Krämer, Alwin, Gerdt Hübner, Andreas Schneeweiss, Gunnar Folprecht, and Kai Neben. "Carcinoma of Unknown Primary – an Orphan Disease?" Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136631.

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Carcinoma of unknown primary (CUP) is an intriguing clinical finding that is defined as biopsy-proven metastasis from a malignancy in the absence of an identifiable primary site after a complete clinical work-up. CUP is a relatively common clinical entity, accounting for approximately 3–5% of all cancer diagnoses, and consists of a heterogeneous group of tumors that have acquired the capacity to metastasize before the development of a clinically evident primary lesion. Notable advances have been made over the past years in the treatment of well-defined clinical subgroups of CUP, such as women with peritoneal carcinomatosis and young adults with poorly differentiated carcinomas of midline distribution, but for the majority of patients, the prognosis still remains poor. In this review, we highlight recent advances in the diagnosis and treatment of patients with CUP syndrome, and emphasize the importance of identifying several favorable subsets of CUP, amenable to specific treatment options. In addition, we will point out novel diagnostic and therapeutic approaches which will hopefully improve both our understanding and the prognosis of this more or less neglected disease
Unter dem Cancer of Unknown Primary (CUP)-Syndrom werden diejenigen Tumorerkrankungen zusammengefasst, bei denen auch nach Abschluss der Diagnostik nur Metastasen, jedoch kein Primärtumor gefunden wird. Das CUP-Syndrom macht ca. 3–5% aller neu diagnostizierten Malignomfälle aus und umfasst eine heterogene Gruppe von Tumoren, die die Fähigkeit zur Metastasierung erlangt haben bevor sich ein klinisch manifester Primärtumor entwickelt hat. Obwohl bemerkenswerte Fortschritte in der Behandlung von Patienten mit bestimmten, gut definierten Erkrankungssubgruppen, wie beispielsweise Frauen mit isolierter Peritonealkarzinose oder jungen Erwachsenen mit gering differenzierten Karzinomen mit Mittellinienverteilung, erzielt werden konnten, ist die Prognose bei der Mehrzahl der Patienten nach wie vor schlecht. Wir berichten im weiteren Verlauf dieser Übersichtsarbeit über Fortschritte in der Diagnostik und Therapie von Patienten mit CUPSyndrom und weisen darauf hin, dass es trotz der immer noch sehr schlechten Prognose von großer Bedeutung ist, Patienten mit bestimmten Subtypen des CUP-Syndroms zu identifizieren, die spezifischen Therapien mit der Option auf Heilung zugeführt werden sollten. Darüber hinaus möchten wir auf neuere diagnostische und therapeutische Bestrebungen aufmerksam machen, die das Verständnis und die Prognose dieses auch in der Onkologie bisher stiefmütterlich behandelten Krankheitsbildes hoffentlich verbessern werden
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich
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Krämer, Alwin, Gerdt Hübner, Andreas Schneeweiss, Gunnar Folprecht, and Kai Neben. "Carcinoma of Unknown Primary – an Orphan Disease?" Karger, 2008. https://tud.qucosa.de/id/qucosa%3A27719.

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Carcinoma of unknown primary (CUP) is an intriguing clinical finding that is defined as biopsy-proven metastasis from a malignancy in the absence of an identifiable primary site after a complete clinical work-up. CUP is a relatively common clinical entity, accounting for approximately 3–5% of all cancer diagnoses, and consists of a heterogeneous group of tumors that have acquired the capacity to metastasize before the development of a clinically evident primary lesion. Notable advances have been made over the past years in the treatment of well-defined clinical subgroups of CUP, such as women with peritoneal carcinomatosis and young adults with poorly differentiated carcinomas of midline distribution, but for the majority of patients, the prognosis still remains poor. In this review, we highlight recent advances in the diagnosis and treatment of patients with CUP syndrome, and emphasize the importance of identifying several favorable subsets of CUP, amenable to specific treatment options. In addition, we will point out novel diagnostic and therapeutic approaches which will hopefully improve both our understanding and the prognosis of this more or less neglected disease.
Unter dem Cancer of Unknown Primary (CUP)-Syndrom werden diejenigen Tumorerkrankungen zusammengefasst, bei denen auch nach Abschluss der Diagnostik nur Metastasen, jedoch kein Primärtumor gefunden wird. Das CUP-Syndrom macht ca. 3–5% aller neu diagnostizierten Malignomfälle aus und umfasst eine heterogene Gruppe von Tumoren, die die Fähigkeit zur Metastasierung erlangt haben bevor sich ein klinisch manifester Primärtumor entwickelt hat. Obwohl bemerkenswerte Fortschritte in der Behandlung von Patienten mit bestimmten, gut definierten Erkrankungssubgruppen, wie beispielsweise Frauen mit isolierter Peritonealkarzinose oder jungen Erwachsenen mit gering differenzierten Karzinomen mit Mittellinienverteilung, erzielt werden konnten, ist die Prognose bei der Mehrzahl der Patienten nach wie vor schlecht. Wir berichten im weiteren Verlauf dieser Übersichtsarbeit über Fortschritte in der Diagnostik und Therapie von Patienten mit CUPSyndrom und weisen darauf hin, dass es trotz der immer noch sehr schlechten Prognose von großer Bedeutung ist, Patienten mit bestimmten Subtypen des CUP-Syndroms zu identifizieren, die spezifischen Therapien mit der Option auf Heilung zugeführt werden sollten. Darüber hinaus möchten wir auf neuere diagnostische und therapeutische Bestrebungen aufmerksam machen, die das Verständnis und die Prognose dieses auch in der Onkologie bisher stiefmütterlich behandelten Krankheitsbildes hoffentlich verbessern werden.
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
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Warnecke, Marei. "Untersuchungen zur Funktion des nukleären Orphan-Rezeptors Ear2." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972556923.

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Books on the topic "Orphan"

1

Weber, John. Orphan. Lodi, N.J: WestSide Books, 2010.

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Weber, John. Orphan. Lodi, N.J: WestSide Books, 2010.

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ill, Coombs Christine Knight, ed. Orphan. Exeter, N.H: J.N. Townsend Pub., 1990.

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Peters, Laura. Orphan texts: Victorian orphans, culture and empire. Manchester: Manchester University Press, 2000.

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Vossler, Bill. Orphan tractors. Osceola, WI: Motorbooks International Publishers & Wholesalers, 1996.

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Petch, Fionn, ed. Orphan World. Edinburgh, Scotland: Charco Press, 2019.

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Orphan Island. New York, NY: HarperCollins Publishers, 2017.

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Foster, Alan Dean. Orphan Star. New York: Random House Publishing Group, 2002.

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Orphan drugs. [s.l.]: Istos, 1999.

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Blyth, Joan. Orphan Mary. Aylesbury: Ginn, 1991.

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Book chapters on the topic "Orphan"

1

Weik, Martin H. "orphan." In Computer Science and Communications Dictionary, 1196. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_13266.

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Lyle, W. H. "Orphan drugs—or orphan diseases?" In The Focus for Pharmaceutical Knowledge, 230–38. London: Macmillan Education UK, 1988. http://dx.doi.org/10.1007/978-1-349-09571-1_29.

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Spilker, Bert. "Orphan Drugs." In Principles and Practice of Pharmaceutical Medicine, 264–74. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444325263.ch22.

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Scarpa, Maurizio, Cinzia Bellettato, and Christina Lampe. "Orphan Drugs." In Drug Discovery and Evaluation: Pharmacological Assays, 4053–69. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-05392-9_137.

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Ludwig, Wolf-Dieter, and Ulrich Schwabe. "Orphan-Arzneimittel." In Arzneiverordnungs-Report 2019, 213–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-59046-1_5.

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Nahler, Gerhard. "orphan diseases." In Dictionary of Pharmaceutical Medicine, 127. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_979.

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Nahler, Gerhard. "orphan drug." In Dictionary of Pharmaceutical Medicine, 127–28. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_980.

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Maldonado, Fabien, Sara Tomassetti, and Jay H. Ryu. "Orphan Tracheopathies." In Orphan Lung Diseases, 73–89. London: Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-2401-6_6.

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Weik, Martin H. "orphan line." In Computer Science and Communications Dictionary, 1196. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_13267.

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Taylor, Karen Heller. "Orphan Rabbits." In Hand-Rearing Wild and Domestic Mammals, 5–12. Oxford, UK: Blackwell Publishing Ltd, 2008. http://dx.doi.org/10.1002/9780470385005.ch1.

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Conference papers on the topic "Orphan"

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Venher, Viktoriia. "Features of the state policy in the field of social security for orphans and children deprived of parental care." In Sociology – Social Work and Social Welfare: Regulation of Social Problems. Видавець ФОП Марченко Т.В., 2023. http://dx.doi.org/10.23939/sosrsw2023.205.

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Background. Unfortunately, according to the Ministry of Social Policy, as of 2022, there were almost 70,000 orphans and children deprived of parental care in Ukraine, and about 10,000 children become orphans every year. Knowing that we are now living in a difficult time, a time of war, we understand that the number of orphans and children deprived of parental care will increase even more, so the state must provide every child with the necessary protection and care that is necessary for their well-being, taking into account her guardians or other persons responsible to her by law, and to this end take all appropriate measures to give the child the opportunity to develop comprehensively and adapt to life in society. Purpose: determine the specifics of providing state social assistance to orphans and children deprived of parental care. Methods: method of analysis, synthesis, comparative method and generalization, analysis of documents. Results: Depending on the form of state social assistance provided to orphans and children deprived of parental care, they can be divided into: 1) state social assistance provided in cash (full state support, scholarship, special scholarships, assistance for orphans and children deprived of parental care, reimbursement of daily expenses during vacations, one-time monetary assistance for graduates, etc.); 2) state social benefits provided in kind (housing, etc.). 3) Social patronage and social support as the main forms of social assistance to orphans and children deprived of parental care. Conclusion: state social assistance for children is awarded in monetary form to foster parents for each foster child and to adoptive parents for each adopted child, and in accordance with the legislation, the amount of state social assistance for an orphan child or a child deprived of parental care is 2.5 subsistence minimums for children of the appropriate age, for children with disabilities - 3.5 subsistence minimums. Keywords: an orphan child; children deprived of parental care; social patronage; social support.
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Doudou, Slimane, Jennifer McTeer, Stephen Wickham, Rob Thied, Richard Woodcock, Tom Turner, Clive Hamblin, Matthew Buckley, and Ciara Walsh. "Optimised Management of Orphan Wastes in the UK." In ASME 2013 15th International Conference on Environmental Remediation and Radioactive Waste Management. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icem2013-96330.

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Orphan wastes have properties preventing them from being managed according to existing or currently planned management routes, or lack characterisation so that their management is uncertain. The identification of new management opportunities for orphan wastes could realise significant benefits by reducing the number of processing facilities required, reducing waste volumes, reducing hazard or leading to the development of centres of excellence for the processing of certain types of orphan wastes. Information on the characteristics of orphan waste existing at nuclear licensed sites across the UK has been collated and a database developed to act as a repository for the information gathered. The database provides a capability to analyse the data and to explore possible treatment technologies for each orphan waste type. Thirty five distinct orphan waste types have been defined and possible treatment options considered. Treatment technologies (including chemical, high temperature, immobilisation and physical technologies) that could be applied to one or more of the generic orphan waste streams have been identified. Wiring diagrams have been used to highlight the waste treatment / lifecycle management options that are available for each of the generic orphan groups as well as identifying areas for further research and development. This work has identified the potential for optimising the management of orphan wastes in a number of areas, and many potential opportunities were identified. Such opportunities could be investigated by waste managers at waste producing nuclear sites, to facilitate the development of new management routes for orphan wastes.
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Prasad, Dhanyamraju S. U. M., and Satya Sai Prakash Kanakadandi. "Orphan Defects: Chance Finding?" In 2014 Artificial Intelligence with Applications in Engineering and Technology (ICAIET). IEEE, 2014. http://dx.doi.org/10.1109/icaiet.2014.22.

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JERBI, Wassim, Abderrahmen GUERMAZI, and Hafedh TRABELSI. "A Routing Protocol Orphan-Leach to Join Orphan Nodes in Wireless Sensor Network." In The Second International Conference on Computer Science, Engineering and Information Technology. Academy & Industry Research Collaboration Center (AIRCC), 2016. http://dx.doi.org/10.5121/csit.2016.60412.

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Smywinska Pohl, Anna. "THE ROBLEM OF ORPHAN WORKS." In 2nd International Multidisciplinary Scientific Conference on Social Sciences and Arts SGEM2015. Stef92 Technology, 2015. http://dx.doi.org/10.5593/sgemsocial2015/b21/s5.102.

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Hudec, R. "Searches for Orphan Optical Afterglows." In GAMMA-RAY BURST AND AFTERGLOW ASTRONOMY 2001: A Workshop Celebrating the First Year of the HETE Mission. AIP, 2003. http://dx.doi.org/10.1063/1.1579378.

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Hudec, R. "Optical Orphan Afterglows: Observational Aspects." In GAMMA-RAY BURSTS: 30 YEARS OF DISCOVERY: Gamma-Ray Burst Symposium. AIP, 2004. http://dx.doi.org/10.1063/1.1810891.

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Zamharira, Cut, and Muqni Abdullah. "Aceh Tsunami Orphan Reinforcement through Orphan Kafala Program Policy, NGO Collaboration (OIC Alliance) with the Aceh Government." In Proceedings of the 1st International Symposium on Indonesian Politics, SIP 2019, 26-27 June 2019, Central Java, Indonesia. EAI, 2019. http://dx.doi.org/10.4108/eai.25-6-2019.2287971.

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Imtiaz, Muhammad Anas, David Starobinski, and Ari Trachtenberg. "Characterizing Orphan Transactions in the Bitcoin Network." In 2020 IEEE International Conference on Blockchain and Cryptocurrency (ICBC). IEEE, 2020. http://dx.doi.org/10.1109/icbc48266.2020.9169449.

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Le Guerroué, E., P. Y. Chenet, B. Lebreuilly, P. Jermannaud, D. McCallum, V. Mitchell, N. Montevecchi, I. Atkinson, and R. Wright. "Potential of the Orphan Basin, NL, Canada." In 79th EAGE Conference and Exhibition 2017. Netherlands: EAGE Publications BV, 2017. http://dx.doi.org/10.3997/2214-4609.201700888.

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Reports on the topic "Orphan"

1

Macnab, R. Aeromagnetic Profiles Northeast of Orphan Basin. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1988. http://dx.doi.org/10.4095/130573.

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Herlihy, Maurice, Nancy Lynch, Michael Merritt, and William Weihl. On the Correctness of Orphan Management Algorithms. Fort Belvoir, VA: Defense Technical Information Center, August 1989. http://dx.doi.org/10.21236/ada213777.

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Markowitz, Steven C. Central-Server-Based Orphan Detection for Argus. Fort Belvoir, VA: Defense Technical Information Center, May 1990. http://dx.doi.org/10.21236/ada226133.

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Bartel, S. D., and D. C. Mosher. Orphan Basin seismic data compilation, 2003-2008. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2009. http://dx.doi.org/10.4095/248062.

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Xie, Wen. Functional Estrogen Deprivation by activating the Orphan Nuclear Receptor PXR. Fort Belvoir, VA: Defense Technical Information Center, August 2004. http://dx.doi.org/10.21236/ada429003.

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Zhang, Xiao-kun. Orphan Receptor TR3/nur77 and Apoptosis in Prostate Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada410922.

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Ruffman, A., and J. E. van Hinte. Devonian Shelf - Depth Limestone Dredged From Orphan Knoll: a 1971 Discovery and a Reassessment of the Hudson 78-020 Dredge Hauls From Orphan Knoll. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1989. http://dx.doi.org/10.4095/130698.

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Dawson, Ian K., Prasad Hendre, Wayne Powell, Daniel Sila, Stepha McMullin, Tony Simons, Cesar Revoredo-Giha, et al. Supporting human nutrition in Africa through the integration of new and orphan crops into food systems: placing the work of the African Orphan Crops Consortium in context. World Agroforestry Centre, 2018. http://dx.doi.org/10.5716/wp18003.pdf.

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Zhou, Ge. The Role of Orphan Nuclear Receptor CUP-TFII in Prostate Development and Tumorigenesis. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada402426.

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DiRenzo, James. Inhibition of Estrogen Receptor Action by the Orphan Receptors, SHP and DAX-1. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada403608.

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