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1

Roberts-Harry, D., and J. Sandy. "Orthodontics. Part 11: Orthodontic tooth movement." British Dental Journal 196, no. 7 (April 2004): 391–94. http://dx.doi.org/10.1038/sj.bdj.4811129.

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2

Wise, G. E., and G. J. King. "Mechanisms of Tooth Eruption and Orthodontic Tooth Movement." Journal of Dental Research 87, no. 5 (May 2008): 414–34. http://dx.doi.org/10.1177/154405910808700509.

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Teeth move through alveolar bone, whether through the normal process of tooth eruption or by strains generated by orthodontic appliances. Both eruption and orthodontics accomplish this feat through similar fundamental biological processes, osteoclastogenesis and osteogenesis, but there are differences that make their mechanisms unique. A better appreciation of the molecular and cellular events that regulate osteoclastogenesis and osteogenesis in eruption and orthodontics is not only central to our understanding of how these processes occur, but also is needed for ultimate development of the means to control them. Possible future studies in these areas are also discussed, with particular emphasis on translation of fundamental knowledge to improve dental treatments.
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3

Mustaffa, Musliana, and Siti Hajjar Nasir. "Endodontics-orthodontics interrelationship: a review." IIUM Journal of Orofacial and Health Sciences 2, no. 2 (July 31, 2021): 4–15. http://dx.doi.org/10.31436/ijohs.v2i2.94.

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The endodontic-orthodontic interface is not well understood due to the limited scientific literature on the topic. This article aims to provide an overview of the orthodontic treatment and the risk of root resorption, the effects of orthodontic tooth movement on dental pulp and endodontically treated teeth, the role of orthodontics in endodontic-restorative treatment planning, and interdisciplinary patient management. Articles published in English from 1982 to 2021 were searched manually from google scholar using keywords ‘endodontic-orthodontic interface’ and ‘endodontic-orthodontic interrelationship’. Another search engine was MEDLINE/PubMed database using keywords ‘endodontics AND orthodontics’, ‘orthodontic tooth movement AND dental pulp’, 'orthodontic tooth movement AND endodontic treatment' and ‘orthodontics AND dental trauma’. Other relevant articles were obtained from the references of the selected papers. Alterations to the dental pulp following orthodontic tooth movement can be histologic and/or cell biological reactions as well as the increased response threshold to pulp sensibility tests. However, the occurrence of root resorption is complex and multifactorial, and can be linked to individual variation, genetic predisposition and orthodontic treatment-related factors. Endodontically treated teeth can move as readily and respond similarly to orthodontic forces as vital teeth, however with inadequate endodontic treatment, the risk of apical inflammation and bone destruction following orthodontic tooth movement is increased. Dental treatment that involves endodontic and orthodontic specialities should be carefully planned according to the individual case, taking into consideration the skills and experience of the clinicians while applying interdisciplinary patient management and available scientific data.
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4

Shetty, Dr Sharath Kumar, Dr Shylashree S, Dr Mahesh Kumar Y, and Dr S. V. Paramesh Gowda. "PRP as a New Effective and Minimally Invasive Accelerated Orthodontic Technique – A Literature Review." Scholars Journal of Dental Sciences 8, no. 7 (August 6, 2021): 199–202. http://dx.doi.org/10.36347/sjds.2021.v08i07.003.

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Acceleration of tooth movement is always a concern of both orthodontist and patient. Demand for shorter treatment time with none to minimal side effects is a main request of orthodontic treatment. The submucosal injection of PRP is a clinically feasible and effective technique to accelerate orthodontic tooth movement and at the same time, preserve the alveolar bone on the pressure side of orthodontic tooth movement, and the optimal dose of PRP for the best clinical performance is 11.0–12.5 folds.
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5

Pathak, Prajwal, Rini Banerjee, Saksham Duseja, and Tarun Sharma. "Newer orthodontic archwires: A review." International Journal of Oral Health Dentistry 8, no. 1 (March 15, 2022): 27–30. http://dx.doi.org/10.18231/j.ijohd.2022.007.

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Orthodontics is a constantly evolving science, with new biomaterials being invented regularly. Orthodontic archwires are an integral part of orthodontic fixed appliances and are necessary for the delivery of forces that brings about biologic tooth movement. As an orthodontist, one needs to have a thorough understanding of the various biomaterials available to make maximum use of these archwires and achieve clinical success. This article discusses the newest orthodontic archwires and evaluates the literature that pertains to these newer archwires.
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6

Shivalinga, BM, H. Jyothikiran, and Vishal Devendrakumar Patel. "Enroute through Bone: Biology of Tooth Movement." World Journal of Dentistry 3, no. 1 (2012): 55–59. http://dx.doi.org/10.5005/jp-journals-10015-1128.

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ABSTRACT Biology of orthodontic tooth movement has always been an interesting field of orthodontist. Orthodontic tooth movement is divided into different phases and number of theories has been given for it, at present most of them are invalid. Gene-directed protein synthesis, modification and integration form the essence of all life processes, including OTM. Bone adaptation to orthodontic force depends on normal osteoblast and osteoclast genes that correctly express needed proteins at the right time and places. Prostaglandins, cytokines and growth factors play an important role in OTM. How to cite this article Patel VD, Jyothikiran H, Raghunath N, Shivalinga BM. Enroute through Bone: Biology of Tooth Movement. World J Dent 2012;3(1):55-59.
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7

Rahma Mansyur, Shinta, and Mardiana Andi Adam. "Wilckodontics-an interdisciplinary periodontics-orthodontic approach to accelerate orthodontic treatment time: a literature review." Makassar Dental Journal 11, no. 1 (April 1, 2022): 89–94. http://dx.doi.org/10.35856/mdj.v11i1.517.

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Objective: Orthodontic treatment is the longest dental procedure performed. To accelerate tooth movement, orthodontists and periodontists have developed a new technique, termed Wilckodontics or periodontal accelerated osteogenic orthodontics. This technique combines selective alveolar corticotomy techniques, particulate bone grafts, and orthodontic force. This review aims to discuss the concepts and technique of Wilckodontics as a combination of interdisciplinary treatment. Methods: An internet-based search was conducted to identify various literatures discussing Wilckodontics using several keywords. Results: Wilcko-dontics can accelerate tooth movement in adult patients and shorten treatment time. Compared with conventional orthodontic treatment, this technique shows advantages in terms of treatment cycle and treatment effect. In addition, the Wilckodontics does not increase the risk of root resorption, periodontium injury, and alveolar bone defects. Conclusion: Wilckodontics re-quires various diagnostic parameters and modification of the procedure. With the right synergy of orthodontist and periodon-tist, successful treatment can be achieved.
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8

Gellee, T., E. Ouadi, A. L. Ejeil, and N. Moreau. "Other interesting effects of alveolar corticotomies in orthodontics apart from the acceleration of tooth movement." Journal of Dentofacial Anomalies and Orthodontics 21, no. 2 (April 2018): 208. http://dx.doi.org/10.1051/odfen/2018057.

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The acceleration of orthodontic tooth movement due to alveolar corticotomies has been well documented in the literature. It is defined by a phenomenon of transient osteopenia named “the regional acceleratory phenomenon” by Frost. This biological mechanism has been described in studies on both humans and animals. However, other interesting effects in orthodontics are associated with alveolar corticotomies: higher amplitude of tooth movements, a decrease of the root resorptions and an increase of stability after orthodontic treatment.
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9

Cadenas de Llano-Pérula, María, and Alejandro Iglesias-Linares. "Surgically-based methods to modify orthodontic tooth movement: A literature review." Edorium Journal of Dentistry 2, no. 2 (October 27, 2015): 1–8. http://dx.doi.org/10.5348/d01-2015-8-ra-6.

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Aim: Reducing treatment time in orthodontics is a matter of strong interest for clinicians and patients. Many procedures have been reported in literature in the last years intending to accelerate orthodontic tooth movement by modifying its biological substrate. Among them, surgical techniques are becoming increasingly popular. The aim of the present article is to review these surgical techniques, offering a clear idea of the scientific evidence available in literature and the possible implications of these techniques in the future. Methods: A literature search was performed in the databases MedLine and Scopus, including all article types focused on surgically-based methods to modify tooth movement in combination with orthodontic or orthopedic force. Results: Osteotomy, corticotomy and piezocision are the most representative of the so-called 'surgically facilitated orthodontic techniques (SFOTs)'. Corticotomy and piezocision share the same biological background (Regional acceleratory phenomena or RAP) while osteotomy is based on osteogenic distraction. A historical overview and a description of the techniques are included in the text. Conclusion: Although clinical results are promising, most of the articles concerning SFOTs are studies performed on animals or case reports. There is a need for evidence-based reports and standardized protocols in order to clarify the process behind tooth movement secondary to surgery, biologically speaking. Side effects of the surgeries and stability of the orthodontic treatment on mid to long-term are yet insufficiently reported.
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10

Jordan, Laurence, Pascal Garrec, and Frédéric Prima. "Influence of Shape Memory Properties on Sliding Resistance in Fixed Orthodontic Appliances." Materials Science Forum 706-709 (January 2012): 514–19. http://dx.doi.org/10.4028/www.scientific.net/msf.706-709.514.

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Tooth movements in an orthodontic treatment are the result of an applied force system, wire-bracket-ligature, and the response of the bone tissue. Starting an orthodontic treatment, it is necessary to exercise a sufficient initial force and then to maintain to obtain a continuous tooth movement. Orthodontic wires, which generate the biomechanical forces, usually transfer forces through brackets to trigger tooth movement. In the case of excessive forces of friction, they are behaving as an opposing force with respect to the movement of the tooth, making it sometimes slower or incontrollable [1].
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11

Adachi, H., K. Igarashi, H. Mitani, and H. Shinoda. "Effects of Topical Administration of a Bisphosphonate (Risedronate) on Orthodontic Tooth Movements in Rats." Journal of Dental Research 73, no. 8 (August 1994): 1478–86. http://dx.doi.org/10.1177/00220345940730081301.

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In orthodontics, undesirable movement of anchor teeth during tooth movement and relapse of moved teeth after treatment are the main causes of unsuccessful results. If these tooth movements could be prevented with pharmacological agents, a less complex orthodontic force system and less extensive retention would be required. The purpose of this study was to examine the effect of topical administration of a bisphosphonate (risedronate), a potent blocker of bone resorption, on orthodontic tooth movements in rats. In the first experiment, both the right and left upper first molars were moved buccally with a standardized expansion spring under administration of risedronate. Risedronate solution was injected into the sub-periosteum area adjacent to the left upper first molar. The right first molar served as a control with an injection of 0.9% NaCl solution. The topical administration of risedronate caused a significant and dose-dependent reduction of tooth movement after the orthodontic force was applied. In the second experiment, the right and left upper molars were first moved buccally for three weeks. The spring was then removed, and administration of risedronate was begun. The topical administration of risedronate inhibited relapse of the tooth in a dose-dependent manner. The administration of risedronate did not affect either overall growth of the animals or longitudinal growth of tibiae. These results suggest that topical application of risedronate may be helpful in anchoring and retaining teeth under orthodontic treatment.
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12

Sawas, Mohamed, Zyad Alsaghir, Fawziah Aldosari, Raghdan Hafiz, Mohammed Alghamdi, Nawaf Alshammari, Ahmed Althuqbi, Khalid Alghamdi, Nasser Hamdan, and Turki Safhi. "Methods and Technology Used to Accelerate Dental Movements in Orthodontic Treatments." Journal of Healthcare Sciences 03, no. 01 (2023): 78–83. http://dx.doi.org/10.52533/johs.2023.30113.

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Due to the overwhelming desire among adults for shorter orthodontic treatment times, there is a growing trend in research that focuses on accelerating procedures for tooth movement. Unfortunately, lengthy orthodontic treatment times come with a number of adverse effects, including an increased risk of tooth decay, gingival recession, and root resorption. Finding the greatest way to maximize tooth motion with the least drawbacks is now more important than ever. The surgical method provides the most dependable results, but its invasiveness limits its use. Corticotomy is one of the commonly used techniques in practice for acceleration of orthodontic tooth movement. Numerous corticotomy methods have been successful in causing accelerated tooth movement. Through the use of these approaches, local acceleratory phenomena are activated, fostering an ideal milieu for tooth movement acceleration. In order to expedite orthodontic tooth movement while adhering to a specified surgical and orthodontic regimen, the piezocision treatment appears to be the ideal compromise. In cases of dehiscence and/or fenestration on the alveolar bone linked to moderate to severe overcrowding, piezocision surgery enables the inclusion of biomaterials. Low-level laser therapy and orthognathic surgery-first are also methods used to accelerate tooth motion among various others. However, further research should be done to ascertain the optimal way to accelerate tooth movement because each approach has benefits and drawbacks. The purpose of this research is to review the available information about methods and technology used to accelerate dental movements in orthodontic treatments..
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13

Makrygiannakis, Miltiadis A., Eleftherios G. Kaklamanos, and Athanasios E. Athanasiou. "Does long-term use of pain relievers have an impact on the rate of orthodontic tooth movement? A systematic review of animal studies." European Journal of Orthodontics 41, no. 5 (December 27, 2018): 468–77. http://dx.doi.org/10.1093/ejo/cjy079.

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Summary Background Pain relief drugs are used and misused widely and may theoretically affect the events leading to orthodontic tooth movement. Objective To systematically investigate and appraise the quality of the available evidence regarding the effect of pain relief medications on the rate of orthodontic tooth movement. Search methods Search without restrictions in eight databases (including grey literature) and hand searching until October 2018. Selection criteria Animal controlled studies investigating the effect of pain relievers on the rate of orthodontic tooth movement. Data collection and analysis Following study retrieval and selection, relevant data were extracted and the risk of bias was assessed using the SYRCLE’s risk of bias tool. Results Fourteen studies were finally identified, most of which at unclear risk of bias. Ibuprofen and loxoprofen did not show any significant effects on the rate of orthodontic tooth movement, whereas indomethacin, ketorolac, morphine, and high doses of etoricoxib were found to decrease it. Inconsistent or conflicting effects were noted after the administration of acetaminophen, acetylsalicylic acid, celecoxib, meloxicam, and tramadol. The quality of the available evidence was considered at best as low. Conclusions Long-term consumption of pain relievers may affect the rate of orthodontic tooth movement. The orthodontist should be capable of identifying patients taking pain relievers independently of orthodontic treatment and consider the possible implications. Trial registration PROSPERO (CRD42017078208).
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14

Makrygiannakis, Miltiadis A., Eleftherios G. Kaklamanos, and Athanasios E. Athanasiou. "Medication and orthodontic tooth movement." Journal of Orthodontics 46, no. 1_suppl (March 28, 2019): 39–44. http://dx.doi.org/10.1177/1465312519840037.

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As any pharmaceutical substance may influence the events associated with orthodontic tooth movement, it is of importance for the clinician to be able to recognize any prospective patient’s history and patterns of medicinal consumption. This review presents the effects of various commonly prescribed medications on the rate of orthodontic tooth movement. The article concludes that it remains, to a degree, unclear which types of medication may have a clinically significant effect in everyday clinical scenarios. However, since both prescription and over-the-counter medication use have recently increased significantly among all age groups, good practice suggests that it is important to identify patients consuming medications and consider the possible implications in orthodontic therapy.
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15

Karthi, Muthukumar, GobichettipalyamJagtheeswaran Anbuslevan, KullampalyamPalanisamy Senthilkumar, Senthilkumar Tamizharsi, Subramani Raja, and Krishnan Prabhakar. "NSAIDs in orthodontic tooth movement." Journal of Pharmacy and Bioallied Sciences 4, no. 6 (2012): 304. http://dx.doi.org/10.4103/0975-7406.100280.

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16

Kumar, AAnand, K. Saravanan, SSathesh Kumar, and K. Kohila. "Biomarkers in orthodontic tooth movement." Journal of Pharmacy and Bioallied Sciences 7, no. 6 (2015): 325. http://dx.doi.org/10.4103/0975-7406.163437.

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17

Kamboj, Ashish. "Malocclusion and orthodontic tooth movement." IP Indian Journal of Orthodontics and Dentofacial Research 8, no. 2 (May 15, 2022): 73–74. http://dx.doi.org/10.18231/j.ijodr.2022.013.

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18

Lee, Won. "Corticotomy for orthodontic tooth movement." Journal of the Korean Association of Oral and Maxillofacial Surgeons 44, no. 6 (2018): 251. http://dx.doi.org/10.5125/jkaoms.2018.44.6.251.

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19

Jiang, C., Z. Li, H. Quan, L. Xiao, J. Zhao, C. Jiang, Y. Wang, et al. "Osteoimmunology in orthodontic tooth movement." Oral Diseases 21, no. 6 (August 14, 2014): 694–704. http://dx.doi.org/10.1111/odi.12273.

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20

Sandy, J. R. "Tooth eruption and orthodontic movement." British Dental Journal 172, no. 4 (February 1992): 141–49. http://dx.doi.org/10.1038/sj.bdj.4807796.

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21

Kanzaki, Hiroyuki, and Yoshiki Nakamura. "Orthodontic tooth movement and HMGB1." Journal of Oral Biosciences 60, no. 2 (June 2018): 49–53. http://dx.doi.org/10.1016/j.job.2018.03.002.

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Singh, Sushil Kumar. "Interleukins in Orthodontic Tooth Movement." Journal of Orofacial & Health Sciences 7, no. 1to3 (2016): 18. http://dx.doi.org/10.5958/2229-3264.2016.00004.6.

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23

Waddington, R. J., and G. Embery. "Proteoglycans and Orthodontic Tooth Movement." Journal of Orthodontics 28, no. 4 (December 2001): 281–90. http://dx.doi.org/10.1093/ortho/28.4.281.

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24

Mohammed, Abbas H., Dimitris N. Tatakis, and Rosemary Dziak. "Leukotrienes in orthodontic tooth movement." American Journal of Orthodontics and Dentofacial Orthopedics 95, no. 3 (March 1989): 231–37. http://dx.doi.org/10.1016/0889-5406(89)90053-x.

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25

Dhenain, Thomas, Francine Côté, and Tereza Coman. "Serotonin and orthodontic tooth movement." Biochimie 161 (June 2019): 73–79. http://dx.doi.org/10.1016/j.biochi.2019.04.002.

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26

Likitmongkolsakul, Udomsak, Pruittikorn Smithmaitrie, Bancha Samruajbenjakun, and Juthatip Aksornmuang. "Development and Validation of 3D Finite Element Models for Prediction of Orthodontic Tooth Movement." International Journal of Dentistry 2018 (August 30, 2018): 1–7. http://dx.doi.org/10.1155/2018/4927503.

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Objectives. The aim of this study was to develop and validate three-dimensional (3D) finite element modeling for prediction of orthodontic tooth movement. Materials and Methods. Two orthodontic patients were enrolled in this study. Computed tomography (CT) was captured 2 times. The first time was at T0 immediately before canine retraction. The second time was at T4 precisely at 4 months after canine retraction. Alginate impressions were taken at 1 month intervals (T0–T4) and scanned using a digital scanner. CT data and scanned models were used to construct 3D models. The two measured parameters were clinical tooth movement and calculated stress at three points on the canine root. The calculated stress was determined by the finite element method (FEM). The clinical tooth movement was measured from the differences in the measurement points on the superimposed model. Data from the first patient were used to analyze the tooth movement pattern and develop a mathematical formula for the second patient. Calculated orthodontic tooth movement of the second patient was compared to the clinical outcome. Results. Differences between the calculated tooth movement and clinical tooth movement ranged from 0.003 to 0.085 mm or 0.36 to 8.96%. The calculated tooth movement and clinical tooth movement at all reference points of all time periods appeared at a similar level. Differences between the calculated and clinical tooth movements were less than 0.1 mm. Conclusion. Three-dimensional FEM simulation of orthodontic tooth movement was achieved by combining data from the CT and digital model. The outcome of the tooth movement obtained from FEM was found to be similar to the actual clinical tooth movement.
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Fernández-González, Felipe José, Aránzazu Cañigral, Felipe Balbontín-Ayala, José Manuel Gonzalo-Orden, Felix de Carlos, Teresa Cobo, Jose Pedro Fernández-Vázquez, Fernando Sánchez-Lasheras, and José Antonio Vega. "Experimental evidence of pharmacological management of anchorage in Orthodontics: A systematic review." Dental Press Journal of Orthodontics 20, no. 5 (October 2015): 58–65. http://dx.doi.org/10.1590/2177-6709.20.5.058-065.oar.

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Introduction: Orthodontic anchorage is one of the most challenging aspects of Orthodontics. Preventing undesired movement of teeth could result in safer and less complicated orthodontic treatment. Recently, several reviews have been published about the effects of different molecules on bone physiology and the clinical side effects in Orthodontics. However, the effects of local application of these substances on the rate of orthodontic tooth movement have not been assessed.Objectives: The aim of this research was to analyze the scientific evidence published in the literature about the effects of different molecules on orthodontic anchorage.Methods: The literature was systematically reviewed using PubMed/Medline, Scopus and Cochrane databases from 2000 up to July 31st, 2014. Articles were independently selected by two different researchers based on previously established inclusion and exclusion criteria, with a concordance Kappa index of 0.86. The methodological quality of the reviewed papers was performed.Results: Search strategy identified 270 articles. Twenty-five of them were selected after application of inclusion/exclusion criteria, and only 11 qualified for final analysis. Molecules involved in orthodontic anchorage were divided into three main groups: osteoprotegerin (OPG), bisphosphonates (BPs) and other molecules (OMs).Conclusions: Different drugs are able to alter the bone remodeling cycle, influencing osteoclast function and, therefore, tooth movement. Thus, they could be used in order to provide maximal anchorage while preventing undesired movements. OPG was found the most effective molecule in blocking the action of osteoclasts, thereby reducing undesired movements.
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Suparwitri, Sri, Pinandi Sri Pudyani, Sofia Mubarika Haryana, and Dewi Agustina. "Effects of soy isoflavone genistein on orthodontic tooth movement in guinea pigs." Dental Journal (Majalah Kedokteran Gigi) 49, no. 3 (September 30, 2016): 168. http://dx.doi.org/10.20473/j.djmkg.v49.i3.p168-174.

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Background: Osteoblast and osteoclast are the important factor in periodontal tissue remodeling for the orthodontic treatment success. Resorption process takes place in compression area by osteoclast and apposition in the tension area by osteoblast. In general hormone condition and age affect remodeling process. Estrogen has a high contribution in remodelling process and decreased in elderly individual such as menopausal women. Soybean contains isoflavone genistein which has similar structure and activity to estrogen. Many researchers indicate that isoflavone genistein not only has an inhibitor effect in osteoporosis but also has estrogenic and antiestrogenic effect as well. Purpose: The study aimed to investigate the effect of soybean isoflavone genistein administration on osteoblast and osteoclast cells number in orthodontic tooth movement of young and old guinea pigs. Method: The research was quasi-experimental study with post test only with control design. The experimental animals were 24 male guinea pigs that divided into: young guinea pigs (±4 months old) and old guinea pigs (±2.5 years old). Each group was divided into 4 subgroups for receiving the treatment namely; control, orthodontic treatment, genistein treatment and orthodontic+genistein treatment. All of the subjects were sacrificed at day 7 and the specimens were histologically analyzed using tartrate resistance acid phosphatase (TRAP) and hematoxylin eosin (HE) staining and observed using microscope that connected to obtilab and an image raster program. Result: U Mann-Whitney statistical analysis showed there were significant differences in osteoblast cell numbers; between orthodontic treatment and orthodontic+genistein treatment in the old guinea pigs (p=0.004); between orthodontic treatment in the young guinea pig and orthodontic+genistein treatment in the old guinea pig (p=0.016); between orthodontics treatment and orthodontic+genistein treatment in the young guinea pigs (p=0.025). U Mann-Whitney statistical analysis showed there were significant differences in osteoclast cell numbers: between the orthodontic treatment in the old guinea pig and orthodontics+genistein treatment in the young guinea pigs (p=0.007); between orthodontic treatment group in the young guinea pigs and orthodontics+genistein treatment in the old guinea pigs; between orthodontic treatment and orthodontic+ genistein treatment in the young guinea pigs (p=0.007). All groups administered by genistein the numbers of osteoblast in the surrounding of the tension sites increased, while in the surrounding of the compression sites had less osteoclasts; even, there were no osteoclasts found in some samples. Conclusion: Soybean isoflavone genistein administration on orthodontic tooth movement increased osteoblast numbers in the tension sides and decreased osteoclast numbers in the compression sides.
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Yamauchi, Taisuke, Megumi Miyabe, Nobuhisa Nakamura, Mizuho Ito, Takeo Sekiya, Saki Kanada, Rina Hoshino, et al. "Impacts of Glucose-Dependent Insulinotropic Polypeptide on Orthodontic Tooth Movement-Induced Bone Remodeling." International Journal of Molecular Sciences 23, no. 16 (August 10, 2022): 8922. http://dx.doi.org/10.3390/ijms23168922.

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Glucose-dependent insulinotropic polypeptide (GIP) exerts extra-pancreatic effects via the GIP receptor (GIPR). Herein, we investigated the effects of GIP on force-induced bone remodeling by orthodontic tooth movement using a closed-coil spring in GIPR-lacking mice (GIPRKO) and wild-type mice (WT). Orthodontic tooth movements were performed by attaching a 10-gf nickel titanium closed-coil spring between the maxillary incisors and the left first molar. Two weeks after orthodontic tooth movement, the distance of tooth movement by coil load was significantly increased in GIPRKO by 2.0-fold compared with that in the WT. The alveolar bone in the inter-root septum from the root bifurcation to the apex of M1 decreased in both the GIPRKO and WT following orthodontic tooth movement, which was significantly lower in the GIPRKO than in the WT. The GIPRKO exhibited a significantly decreased number of trabeculae and increased trabecular separation by orthodontic tooth movement compared with the corresponding changes in the WT. Histological analyses revealed a decreased number of steady-state osteoblasts in the GIPRKO. The orthodontic tooth movement induced bone remodeling, which was demonstrated by an increase in osteoblasts and osteoclasts around the forced tooth in the WT. The GIPRKO exhibited no increase in the number of osteoblasts; however, the number of osteoclasts on the coil-loaded side was significantly increased in the GIPRKO compared with in the WT. In conclusion, our results demonstrate the impacts of GIP on the dynamics of bone remodeling. We revealed that GIP exhibits the formation of osteoblasts and the suppression of osteoclasts in force-induced bone remodeling.
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Sun, Yuqing, Jingfei Fu, Feiran Lin, Shengnan Li, Juan Du, Yi Liu, and Yuxing Bai. "Force-Induced Nitric Oxide Promotes Osteogenic Activity during Orthodontic Tooth Movement in Mice." Stem Cells International 2022 (September 6, 2022): 1–10. http://dx.doi.org/10.1155/2022/4775445.

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Objectives. The aim of this study was to investigate the effect of nitric oxide (NO) on orthodontic tooth movement and the regulatory effect on bone formation. Design. A mouse orthodontic tooth movement model was established to measure the level of releasing NO. Besides, orthodontic tooth movement distance and the bone formation in the tension side of the orthodontic tooth were also analyzed. In vitro, human periodontal ligament stem cells (hPDLSCs) were cultured under tensile force stimulation. The production of NO and the expression level of nitric oxide synthase (NOS) were detected after mechanical stimulation. Furthermore, the downstream cellular signaling pathway regulated by NO was also explored. Results. The generation of NO steadily increased throughout the orthodontic tooth movement in mice. Orthodontic tooth movement was decreased in the NOS inhibitor group while it was accelerated in the NO precursor group. Force-induced NO promoted the osteogenic differentiation of human hPDLSCs under tensile force stimulation. And force-induced NO in hPDLSCs regulated the PI3K/Akt/β-catenin signal pathway. Conclusion. NO is involved in the regulation of orthodontic tooth movement and promotes bone formation on the tension side of the orthodontic tooth. The PI3K/Akt/β-catenin pathway is one of the downstream cell signal transduction pathways of NO in the orthodontic process.
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Kulshrestha, Rohit, Pavankumar Vibhute, Chetan Patil, Vinay Umale, and Balagangadhar Balagangadhar. "Accelerated Orthodontics: A Review." Dentistry and Oral Maxillofacial Surgery 2, no. 1 (December 30, 2019): 01–06. http://dx.doi.org/10.31579/2643-6612/016.

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Nowadays, there is an increased tendency for researches to focus on accelerating methods for tooth movement due to the greater demand for adults for a shorter orthodontic treatment duration. Unfortunately, long orthodontic treatment time has many disadvantages like higher predisposition to caries, gingival recession, and root resorption. This increases the demand to increase tooth movement with the least possible disadvantages. Several modalities have been reported for accelerating the tooth movement. Thus, accelerating orthodontic tooth movement and the resulting shortening of the treatment time would be quite beneficial.
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Dsouza, Sheehan R., Amitha Ramesh, Sharath K. S., and Biju Thomas. "CORTICOTOMY-PERIODONTALLY ACCELERATED OSTEOGENIC ORTHODONTICS - A SURGICAL TECHNIQUE AND CASE REPORT." Journal of Health and Allied Sciences NU 04, no. 03 (September 2014): 112–14. http://dx.doi.org/10.1055/s-0040-1703815.

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AbstractCorticotomy-assisted orthodontic treatment involves selective alveolar decortication in the form of decortication lines and dots performed around the teeth that are to be moved. It is done to induce a state of increased tissue turnover and a transient osteopenia, which is followed by a faster rate of orthodontic tooth movement.This technique has several advantages, including faster tooth movement, shorter treatment time, safer expansion of constricted arches, enhanced post-orthodontic treatment stability and extended envelope of tooth movement.This case report describes a surgical technique and case report involving periodontally accelerated osteogenic orthodontics.
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33

Long, Hu, Ujjwal Pyakurel, Yan Wang, Lina Liao, Yang Zhou, and Wenli Lai. "Interventions for accelerating orthodontic tooth movement." Angle Orthodontist 83, no. 1 (June 21, 2012): 164–71. http://dx.doi.org/10.2319/031512-224.1.

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Abstract Objective: To evaluate the effectiveness of interventions on accelerating orthodontic tooth movement. Materials and Methods: We searched the databases of PubMed, Embase, Science Citation Index, CENTRAL, and SIGLE from January 1990 to August 2011 for randomized or quasi-randomized controlled trials that assessed the effectiveness of interventions on accelerating orthodontic tooth movement. The processes of study search, selection, and quality assessment were conducted independently in duplicate by two review authors. Original outcome data, if possible, underwent statistical pooling by using Review Manager 5. Results: Through a predefined search strategy, we finally included nine eligible studies. Among them, five interventions were studied (ie, low-level laser therapy, corticotomy, electrical current, pulsed electromagnetic fields, and dentoalveolar or periodontal distraction). Six outcomes were evaluated in these studies (ie, accumulative moved distance or movement rate, time required to move tooth to its destination, anchorage loss, periodontal health, pulp vitality, and root resorption). Conclusion: Among the five interventions, corticotomy is effective and safe to accelerate orthodontic tooth movement, low-level laser therapy was unable to accelerate orthodontic tooth movement, current evidence does not reveal whether electrical current and pulsed electromagnetic fields are effective in accelerating orthodontic tooth movement, and dentoalveolar or periodontal distraction is promising in accelerating orthodontic tooth movement but lacks convincing evidence.
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Agrawal, Miral, Shefali Sharma, and Parmeshwari Rathod. "Periodontally Accelerated Osteogenic Orthodontics (PAOO) vs Osteoperforations (A Review on Periodontal Reactions to Orthodontic Tooth Movement)." Academic Journal of Research and Scientific Publishing 3, no. 32 (December 5, 2021): 36–51. http://dx.doi.org/10.52132/ajrsp.e.2021.32.2.

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A high number of adult patients are undertaking orthodontic treatment now because of the newer methods, technology, and innovations available in the market. Orthodontic profession is continually looking for new ways to perform treatment effectively for such patients, as there are many differences in the biology, motivation, and treatment objectives between adults and children. Aligner therapy and mini-implants are some of the ways of managing orthodontic treatment for adult patients. Treatment time is a concern for adult patients and methods to accelerate the orthodontic tooth movement have been a focus in the orthodontic field. Periodontal accelerated osteogenic orthodontics (PAOO) is a surgical procedure that is performed with a combination of alveolar corticotomy, bone grafting, followed by orthodontic treatment. This procedure uses the principle of regional acceleratory phenomenon (RAP). Another procedure commonly used for accelerated orthodontic tooth movement is osteoperforations. This is a minimally invasive procedure, which does not include a flap surgery. The purpose of this article is to describe the differences between adult and children periodontal tissues, the use of different appliances for adult treatment, how orthodontic treatment has been modified for adult patients, and the detailed explanation of procedures for accelerating orthodontic tooth movement such as PAOO and osteoperforations and the potential complications
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35

Abid, Reem. "Effect of Honey on Orthodontic Tooth Movement and Osteoclastic Activity in Psychologically Stressed Animals." Proceedings of Shaikh Zayed Medical Complex Lahore 35, no. 4 (November 8, 2021): 46–50. http://dx.doi.org/10.47489/pszmc-815354-46-50.

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Introduction: Orthodontics is a clinical specialty in dentistry related to the correction of dentofacial deformities. Psychological stress factors delay Orthodontic tooth movement (OTM). Honey can be considered a useful and harmless natural product to reduce stress levels, hence improves the efficacy of OTM. Aims & Objectives: To compare the differences in the rate of tooth movement and osteoclastic activity between control, psychologically stressed and honey treated psychologically stressed groups after 1 week of orthodontic force application in an animal model. Place and duration of study: This experimental study was conducted at the animal research laboratory and Histopathology Department of Post Graduate Medical Institute (PGMI), Lahore, Pakistan, from April 2019 to June 2020. Material & Methods: Thirty-six Sprague Dawley rats were randomly divided into A, B and C groups. Psychological Stress was induced in group A (PS group) while Honey was given orally as a therapeutic agent along with induction of psychological stress in group B (PSH group), and group C was the Control Group. Statistical analyses were performed using SPSS version 24 software. The quantitative variables were the orthodontic tooth movement, the osteoclast count, and the expression of RANKL. One-way ANOVA was applied to calculate the mean difference and Post hoc Tukey test applied for multiple comparisons among the groups. A p-value ? 0.05 was considered statistically significant in all 3 groups. Results: There was a significant difference (p-value <0.05) between control and experimental groups in the orthodontic tooth movement and levels of RANKL, however, there was no significant difference between PS and PSH groups. Conclusion: Psychological stress delays orthodontic tooth movement by causing a reduction in its rate and osteoclastic activity and honey has no significant correlation with lowering stress levels, hence does not improve orthodontic tooth movement efficiency.
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Mustilwar, Rachita G., Akshaya Narayan Shetti, Amit Mani, and Preeti Prakash Kale. "Ortho-Perio interrelationship - A review." IP International Journal of Periodontology and Implantology 7, no. 4 (November 15, 2022): 150–53. http://dx.doi.org/10.18231/j.ijpi.2022.033.

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For better diagnosis and treatment planning, co-operation, coordination and interaction between different specialties in dentistry are utmost important. Interaction between the different disciplines is necessary and in some cases it is crucial in facilitating coordinated dental therapy. The interrelationship between Orthodontics and Periodontics is many times symbiotic. In many instances, periodontal health is improved by orthodontic tooth movement, whereas orthodontic tooth movement is often facilitated by periodontal therapy. Prior to 1970’s orthodontic treatment not so often recommended to prevent periodontal diseases. Crowded teeth result in plaque accumulation because of difficulty in cleaning. Gingivitis may lead to periodontal diseases. Orthodontic treatment can foster periodontal health and it may also prevent periodontal diseases.
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Andrade Jr, Ildeu, Ana Beatriz dos Santos Sousa, and Gabriela Gonçalves da Silva. "New therapeutic modalities to modulate orthodontic tooth movement." Dental Press Journal of Orthodontics 19, no. 6 (December 2014): 123–33. http://dx.doi.org/10.1590/2176-9451.19.6.123-133.sar.

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Modulation of orthodontic tooth movement (OTM) is desirable not only to patients because it shortens treatment time, but also to orthodontists, since treatment duration is associated with increased risk of gingival inflammation, decalcification, dental caries, and root resorption. The increased focus on the biological basis of tooth movement has rendered Orthodontics a more comprehensive specialty that incorporates facets of all fields of medicine. Current knowledge raises the possibility of using new therapeutic modalities for modulation of OTM, such as corticotomy, laser therapy, vibration (low-intensity pulsed ultrasound), local injections of biomodulators and gene therapy; with the latter being applicable in the near future. They are intended to enhance or inhibit recruitment, differentiation and/or activation of bone cells, accelerate or reduce OTM, increase stability of orthodontic results, as well as assist with the prevention of root resorption. This article summarizes recent studies on each one of these therapeutic modalities, provides readers with information about how they affect OTM and points out future clinical perspectives.
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Ulhaq, Aman, Emma McCrory, and Eleni Besi. "Surgical Methods for Accelerating Orthodontic Tooth Movement." Orthodontic Update 13, no. 4 (October 2, 2020): 170–79. http://dx.doi.org/10.12968/ortu.2020.13.4.170.

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The ability to consistently reduce orthodontic treatment time without adverse outcomes would be an attractive prospect. Several surgical interventions have been described aimed at accelerating orthodontic tooth movement. The aim of this review is to identify and evaluate the current evidence available for surgically-assisted orthodontic tooth movement (OTM). The current evidence suggests that surgical procedures may increase the rate of tooth movement, however, this effect is short lived. Further reporting on total treatment time, and patient centred outcomes, would be beneficial in future studies. CPD/Clinical Relevance: To explain surgical methods for accelerating orthodontic tooth movement.
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Mehta, Shivam, Dolly Patel, and Sumit Yadav. "Staging Orthodontic Aligners for Complex Orthodontic Tooth Movement." Turkish Journal of Orthodontics 34, no. 3 (September 20, 2021): 202–6. http://dx.doi.org/10.5152/turkjorthod.2021.20116.

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40

Mittal, Anil Kumar, Ruchi Sharma, Pratibha Garg, and Amit Sidana. "Single Tooth Intrusion simplified with New Removable Orthodontic Appliance: Report of Two Cases." World Journal of Dentistry 5, no. 4 (2014): 232–36. http://dx.doi.org/10.5005/jp-journals-10015-1296.

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ABSTRACT Intrusion of single anterior tooth done by fixed orthodontic appliance is a tedious procedure for orthodontist as well as for the patient which may be quite expensive and time consuming. The use of a new modified removable orthodontic appliance is illustrated in two case reports in this article which is especially beneficial for such cases. This removable appliance is comprised of a labial bow of 21 gauge stainless steel wire with soldered high labial bow of 19 gauge stainless steel wire which has a soldered hook permitting the use of elastic. Adams clasp and pinhead clasps are used for retention of the appliance. During intrusive force application, one component is for intrusion of tooth and other component is for labial movement. This appliance is fabricated in such a manner that the labial movement is prevented by labial component of wire and is converted into pure intrusive force as much as possible. Force levels used for tooth movement are kept within physiologic limits while using this appliance. A though, this appliance is advantageous over fixed orthodontics due its simpler and quicker chair-side procedure and low cost of treatment associated with patient comfort, patient co-operation is must for the success of this therapy. How to cite this article Mittal AK, Sharma R, Garg P, Sidana A. Single Tooth Intrusion simplified with New Removable Orthodontic Appliance: Report of Two Cases. World J Dent 2014;5(4):232-236.
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41

Lee, R. T. "The Benefits of Post-surgical Orthodontic Treatment." British Journal of Orthodontics 21, no. 3 (August 1994): 265–74. http://dx.doi.org/10.1179/bjo.21.3.265.

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Orthodontic therapy is best carried out in a normal skeletal and soft tissue environment. In patients requiring orthognathic surgery, it is suggested that there are advantages in correcting the skeletal and soft tissue elements as early as possible, and to orthodontically control the occlusion post-operatively. This results in a shorter overall treatment time due to more biologically favourable tooth movement, more predictable occlusal results and better management by the orthodontist. The clinical benefits of post-operative orthodontics are outlined.
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42

Zheng, Junyi, Bowen Xu, and Kai Yang. "Autophagy Regulates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells Induced by Orthodontic Tension." Stem Cells International 2022 (October 4, 2022): 1–17. http://dx.doi.org/10.1155/2022/2983862.

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Tooth movement is the core of orthodontics. Osteogenesis of the tension side under orthodontic force has great significance on tooth movement and stability, which involves complex mechanical and biological signal transduction. However, the mechanism remains unclear. Through in vitro cell studies, we observed the increased expression levels of osteogenesis-related factors and autophagy-related factors during the osteogenic differentiation of mesenchymal stem cells induced by orthodontic force. The change trend of autophagy-related factors and osteogenesis-related factors is similar, which indicates the involvement of autophagy in osteogenesis. In the study of autophagy-related gene ATG7 silenced cells, the expression level of autophagy was significantly inhibited, and the expression level of osteogenesis-related factors also decreased accordingly. Through drug regulation, we observed that the increase of autophagy level could effectively promote osteogenic differentiation, while the decrease of the autophagy level inhibited this process to some extent. Therefore, autophagy plays an important role in the osteogenic differentiation of mesenchymal stem cells induced by orthodontic force, which provides a novel idea useful for orthodontic treatment in promoting periodontal tissue remodeling and accelerating tooth movement.
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43

Choi, Hyung-Joo, Dong-Yeol Lee, and Tae-Woo Kim. "Dynamics of Alloplastic Bone Grafts on an Early Stage of Corticotomy-Facilitated Orthodontic Tooth Movement in Beagle Dogs." BioMed Research International 2014 (2014): 1–13. http://dx.doi.org/10.1155/2014/417541.

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Alveolar augmented corticotomy is effective in accelerating orthodontic tooth movement, but the effect only lasts for a relatively short time. Therefore, the purpose of this study was to investigate the underlying biology of the immediate periodontal response to orthodontic tooth movement after a corticotomy with alloplastic bone grafts. The results demonstrated that measurable tooth movement began as early as 3 days after the intervention in beagle dogs. Based on the results and histological findings, augmented corticotomy-facilitated orthodontic tooth movement might enhance the condition of the periodontal tissue and the stability of the outcomes of orthodontic treatment.
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44

Kaklamanos, Eleftherios G., Miltiadis A. Makrygiannakis, and Athanasios E. Athanasiou. "Does medication administration affect the rate of orthodontic tooth movement and root resorption development in humans? A systematic review." European Journal of Orthodontics 42, no. 4 (August 18, 2019): 407–14. http://dx.doi.org/10.1093/ejo/cjz063.

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Summary Background Recently, the potential impact of different medications on the rate of orthodontic tooth movement and the associated root resorption has been systematically reviewed in animal studies and various effects have been shown. However, animal data cannot be extrapolated to human clinical situations directly. Objectives To systematically investigate the most up to date available evidence from controlled human studies regarding the effect of medication administration on the rate of orthodontic tooth movement and associated root resorption development. Search methods We searched eight databases (covering also grey literature) without restrictions and we performed hand searching up until October 2018. Selection criteria Controlled studies in humans assessing the effect of various medications on the rate of orthodontic tooth movement and root resorption development. Data collection and analysis Study selection was followed by data extraction and risk of bias assessment using the ROBINS-I tool for non-randomized and the Cochrane Risk of Bias Tool for randomized studies. Results Eight studies, at various risk of bias, were finally identified. With regard to the rate of orthodontic tooth movement, local injections of prostaglandin E1 were found to exert an increasing effect, whereas systemic intake of nabumetone decreased it. Following tenoxicam administration, drinking water with fluoride or local injections of calcitriol (vitamin D metabolite), no significant effects were demonstrated. Concerning root resorption development, nabumetone administration was shown to reduce it, whereas fluoride, overall, was not observed to exert any effect. Only in individuals subjected to heavy orthodontic forces, did fluoride show a protective effect for the period of force application, but not in the longer term during retention. Conclusions The aforementioned substances may show varying effects on the rate of orthodontic tooth movement and root resorption development in human subjects. Despite the observed limitations, the orthodontist should be able to identify patients taking pharmaceuticals and consider any implications related to orthodontic treatment. Registration PROSPERO (CRD42017078208).
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Eltimamy, Ahmed, Fouad Aly El-Sharaby, Faten Hussien Eid, and Amr Emad El-Dakrory. "The Effect of Local Pharmacological Agents in Acceleration of Orthodontic Tooth Movement: A Systematic Review." Open Access Macedonian Journal of Medical Sciences 7, no. 5 (March 16, 2019): 882–86. http://dx.doi.org/10.3889/oamjms.2019.203.

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AIM: Acceleration of orthodontic tooth movement has gained a massive interest to decrease the total treatment time. Local pharmacological agents might be used for that purpose as a practical, effective and inexpensive alternative. A systematic review was achieved to evaluate the evidence in that topic. METHODS: A search was conducted on electronic databases including PubMed, Lilacs, Web of Science (Thompson Reuters), EMBASE (OvidSP), and Cochrane Database of Systematic Reviews (Wiley) in addition to hand searching of relevant journals till June 2018. Only studies written in English were utilised. Publications were selected, assessed systematically and graded by two observers according to Bondemark grading system. RESULTS: Only two human studies were found investigating the effect of Relaxin and Prostaglandins in the rate of orthodontic tooth movement. No obvious side effects were reported. Relaxin showed no increase in the rate of tooth movement while prostaglandin showed a marked increase in the rate of orthodontic tooth movement. CONCLUSION: There is below moderate evidence showing no effect of relaxin on orthodontic tooth movement, while inconclusive evidence was found regarding Prostaglandin in the acceleration of orthodontic tooth movement. More prospective well-conducted clinical trials are needed to reach a proper conclusion regarding the local pharmacological agents which can be safely used to accelerate orthodontic tooth movement.
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46

Kirschneck, Christian, Nadine Straßmair, Fabian Cieplik, Eva Paddenberg, Jonathan Jantsch, Peter Proff, and Agnes Schröder. "Myeloid HIF1α Is Involved in the Extent of Orthodontically Induced Tooth Movement." Biomedicines 9, no. 7 (July 8, 2021): 796. http://dx.doi.org/10.3390/biomedicines9070796.

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During orthodontic tooth movement, transcription factor hypoxia-inducible factor 1α (HIF1α) is stabilised in the periodontal ligament. While HIF1α in periodontal ligament fibroblasts can be stabilised by mechanical compression, in macrophages pressure application alone is not sufficient to stabilise HIF1α. The present study was conducted to investigate the role of myeloid HIF1α during orthodontic tooth movement. Orthodontic tooth movement was performed in wildtype and Hif1αΔmyel mice lacking HIF1α expression in myeloid cells. Subsequently, µCT images were obtained to determine periodontal bone loss, extent of orthodontic tooth movement and bone density. RNA was isolated from the periodontal ligament of the control side and the orthodontically treated side, and the expression of genes involved in bone remodelling was investigated. The extent of tooth movement was increased in Hif1αΔmyel mice. This may be due to the lower bone density of the Hif1αΔmyel mice. Deletion of myeloid Hif1α was associated with increased expression of Ctsk and Acp5, while both Rankl and its decoy receptor Opg were increased. HIF1α from myeloid cells thus appears to play a regulatory role in orthodontic tooth movement.
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47

Bertossi, Dario, Dario Donadello, Giamaica Conti, Luca Calogero Carletta, Andrea Sbarbati, Claudia Corega, Alessandra Luise Marie Magistretti, et al. "Orthodontics Surgical Assistance (Piezosurgery®): Experimental Evidence According to Clinical Results." Applied Sciences 12, no. 3 (January 20, 2022): 1048. http://dx.doi.org/10.3390/app12031048.

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Orthodontic tooth movement (OTM) is based on intermitted or continuous forces applied to teeth, changing the mechanical loading of the system and arousing a cellular response that leads to bone adaptation. The traditional orthodontic movement causes a remodeling of the alveolar bone and changes in the periodontal structures that lead to tooth movement. The use of a piezoelectric instrument in orthodontic surgery has already shown great advantages. The purpose of this study is to rank the behavior of inflammatory mediators in accelerating orthodontic tooth movement. Ten patients with malocclusion underwent orthodontic surgical treatment, which included a first stage of surgically guided orthodontic movement (monocortical tooth dislocation and ligament distraction, MTDLD) to accelerate orthodontic movements. In all cases, corticotomy was performed by Piezosurgery. Bone and dental biopsy was executed to evaluate changes in the cytokines IL-1beta, TNF-alpha and IL-2 in different time intervals (1, 2, 7, 14 and 28 days). The molecular mediators are IL-1 beta, TNF-alpha and IL-2. Immediately after the surgical procedure there was a mild expression of the three molecular markers, while the assertion of IL-1 beta and TNF-alpha reached the maximum value after 24 h and 48 h, indicating a strong activation of the treated tissues. The Piezosurgery® surgical technique induces an evident stress in short times, within 24–48 h from the treatment, but it decreases significantly during the follow-up.
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48

Mohanty, Pritam, Jugajyoti Pathi, Rajeev Ranjan, Balaji Manohar, Suravi Chatterjee, Samarendra Dash, Swati Verma, and Mohammad Khursheed Alam. "Orthodontic Loop-guided Piezocision (OLP): An innovative precision aid in accelerated tooth movement." Bangladesh Journal of Medical Science 21, no. 2 (February 25, 2022): 470–76. http://dx.doi.org/10.3329/bjms.v21i2.58085.

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The Accelerated osteogenic Orthodontics (AOO) is an emerging contemporary approach for rapid movement of teeth. The acceptable length of orthodontic treatment is contested, however the need for speeding appears to be universally agreed upon. Various surgical adjuncts have been developed to expedite orthodontic tooth movement and to retain optimal occlusal results while shortening treatment timeframes. Despite this, a variety of crucial treatment decisions and approaches may have a greater impact. The purpose of present case study is to suggest a minimally invasive novel orthodontic Loop-guided Piezocision (OLP) approach for quick movement of teeth, without reflection of the flap, with higher precision and minimum postoperative problems. This technique may aid in preventing orthodontic relapse, broaden spectrum of malocclusion correction. This may also eliminates requirement of conventional ortho-surgical procedure, and completes treatment in relatively shorter active orthodontic treatment period. Bangladesh Journal of Medical Science Vol. 21 No. 02 April’22 Page : 470-476
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49

Patel, Dr Nimesh D. "Frontier in Orthodontics – Dental Tooth Movement Acceleration." Scholars Journal of Dental Sciences 8, no. 10 (October 24, 2021): 302–6. http://dx.doi.org/10.36347/sjds.2021.v08i10.002.

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There is an increased tendency for researchers to focus on the methods accelerating tooth movement due to the high demand by adult patients for short orthodontic treatment duration. Unfortunately, longer orthodontic treatment duration poses certain risks such as increase likelihood for caries, gingival recession, and root resorption. This also leads to a higher demand to identify the methods to increase tooth movement with minimum possible side-effects. The purpose of this review is to describe the success approaches in acceleration of tooth movement and to highlight their pros and cons. Biological methods of tooth movement have shown that cytokines, RANKL show good results for accelerating tooth movement and raloxifene is best used for retention as it decreases relapse. Osteotomy and corticotomy are useful in increasing the rate of tooth movement but are invasive. Osteoperforations is less invasive and can give good results for acceleration of orthodontic tooth movement.
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50

Drake, Carl T., Susan P. McGorray, Calogero Dolce, Madhu Nair, and Timothy T. Wheeler. "Orthodontic Tooth Movement with Clear Aligners." ISRN Dentistry 2012 (August 14, 2012): 1–7. http://dx.doi.org/10.5402/2012/657973.

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Clear aligners provide a convenient model to measure orthodontic tooth movement (OTM). We examined the role of in vivo aligner material fatigue and subject-specific factors in tooth movement. Fifteen subjects seeking orthodontic treatment at the University of Florida were enrolled. Results were compared with data previously collected from 37 subjects enrolled in a similar protocol. Subjects were followed prospectively for eight weeks. An upper central incisor was programmed to move 0.5 mm. every two weeks using clear aligners. A duplicate aligner was provided for the second week of each cycle. Weekly polyvinyl siloxane (PVS) impressions were taken, and digital models were fabricated to measure OTM. Initial and final cone beam computed tomography (CBCT) images were obtained to characterize OTM. Results were compared to data from a similar protocol, where subjects received a new aligner biweekly. No significant difference was found in the amount of OTM between the two groups, with mean total OTM of 1.11 mm. (standard deviation (SD) 0.30) and 1.07 mm. (SD 0.33) for the weekly aligner and biweekly control groups, respectively (P=0.72). Over eight weeks, in two-week intervals, material fatigue does not play a significant role in the rate or amount of tooth movement.
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