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Dissertations / Theses on the topic 'Orthognathic surgery'

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1

Tan, Su-keng, and 陳舒卿. "Perioperative antibiotic prophylaxis in orthognathic surgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B4466140X.

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2

Bamber, Mohammad Anwar. "An evaluation of orthognathic surgery planning techniques." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307466.

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3

Okumura, Hideki. "A Study of Computer-Assisted Orthognathic Surgery." Kyoto University, 1999. http://hdl.handle.net/2433/181724.

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4

Singh, Baldev. "Prevalence of postoperative infection after orthognathic surgery." Thesis, Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23234635.

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5

Cunningham, Susan Jane. "Outcomes of orthognathic treatment." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325911.

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6

Stirling, Jacqueline. "Investigating patients' decision making about elective orthognathic surgery." Thesis, University of Leeds, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275776.

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7

Blacker, Jared C. Phillips Ceib. "Medication use and recovery in orthognathic surgery patients." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1502.

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Thesis (M.S.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Master of Science in the School of Dentistry Orthodontics." Discipline: Orthodontics; Department/School: Dentistry.
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8

Liddle, Morna. "Exploring people's experience of appearance-altering orthognathic surgery." Thesis, University of Sheffield, 2011. http://etheses.whiterose.ac.uk/1675/.

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9

Alolayan, Albraa Badr A. "Risk factors of neurosensory disturbance following bimaxillary orthognathic surgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50639511.

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Objectives: To report the incidence of objective and subjective neurosensory disturbance (NSD) after orthognathic surgery in a major orthognathic centre in Hong Kong, and to investigate the risk factors that contributed to the incidence of NSD after orthognathic surgery. Materials and Methods: A retrospective cross-sectional study on NSD after orthognathic surgery in a local major orthognathic centre. Patients who had bimaxillary orthognathic surgery reviewed at post-operative 6 months, 12 months or 24 months were recruited to undergo a neurosensory test with subjective and 3 objective assessments. Possible risk factors of NSD including subjects’ age and gender, surgical procedures and surgeons’ experience were analyzed. Results: 238 patients with 476 sides each of maxillary and mandibular procedures were recruited. The incidences of subjective NSD after maxillary procedures were 16.2%, 13% and 9.8% at post-operative 6 months, 12 months and 24 months, respectively; the incidences of subjective NSD after mandibular procedures were 35.4%, 36.6% and 34.6% at post-operative 6 months, 12 months and 24 months, respectively. Objective neurosensory tests showed general reduced sensitivity in subjects with subjective NSD. Increased age was found to be a significant risk factor of NSD after orthognathic surgery at short term (at 6 months and 12 months) but not at 24 months. SSO has a significantly higher risk of NSD when compared to VSSO. SSO in combination with anterior mandibular surgery has a higher risk of NSD when compared to VSSO in combination with anterior mandibular surgery or anterior mandibular surgery alone. Gender of patients a nd surgeons’ experience were not found to be risk factors of NSD after orthognathic surgery. Conclusion: The incidence of NSD after maxillary and mandibular orthognathic procedures at post-operative 6 months, 12 months and 24 months was reported. Increased age was identified as a risk factor of short term post-operative NSD but not in long term (24 months or more). Specific mandibular procedures were related to higher incidence of NSD after orthognathic surgery.<br>published_or_final_version<br>Dental Surgery<br>Master<br>Master of Dental Surgery
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10

Paul, Ninu. "The orthognathic surgery patient's experience : a Grounded Theory study." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/20395/.

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Objective: Facial visible difference has a range of impacts not only functional and aesthetic but also in terms of the emotional and social wellbeing of patients. The aim of the study is to develop a theory that explains a person’s experience of the orthognathic treatment. Methods: The study was a qualitative cross-sectional grounded theory study. Semi-structured interviews were used to explore the experience of orthognathic patients undergoing treatment in a NHS hospital in the UK. Face to face interviews with 22 orthognathic patients (4 male and 18 female; age range 18-66 years) were conducted. Of these, 12 participants had had surgery six-eight weeks prior to the interview, six were in the decision making phase for orthognathic treatment and four participants had had the surgery one-two years prior to the interview. Further theoretical sampling and data collection was carried out from online blogs and forums on orthognathic treatment. Grounded theory methodology was used for the analysis of the data collected. Results: Analysis of the interviews indicated that during the process of orthognathic surgery, patients go through a status passage of ‘normal facing’. Orthognathic patients were inducted into this passage through their dentists, peer influence in the form of teasing and bullying about facial appearance, knowledge of orthodontic treatment gained from peers and their own perceptions of self-image. Decision making for orthognathic treatment influenced this status passage of ‘normal facing’, which, in turn, was influenced both positively and negatively by external factors. Temporality played a key role in normal facing. The factors that influenced the shape of this passage were the patient’s social support system, post-surgery recovery, quality of care, age of the patient, patient’s own life priorities, the preparedness of the patients in the form of information about the treatment, and the role of professionals involved in care provision. ‘Normal facing’ appeared to positively influence the patient’s coping behaviour and self-perception. Conclusions: Orthognathic patients undergo a scheduled status passage of ‘normal facing’, which appears to be influenced by various clinical, demographic and psychosocial factors. This status passage consequently influenced the person’s self-perception.
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11

Aiello, George A. "Antibiotic prophylaxis in orthognathic surgery : one day vs. five days." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=61326.

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The effect of one day and five day antibiotic administration for prophylaxis in orthognathic surgical procedures was compared.<br>A randomized double-blind clinical trial using placebo was conducted. Thirty patients were equally distributed between two groups. Each group received Penicillin G two million units intravenously pre-operatively, and one million units I.V. every three hours intraoperatively and three hours post-operatively. Group one then received Penicillin G, one million units I.V. every six hours for eight doses, then Penicillin V suspension 300 mg orally every six hours for eight doses. Group two received placebo in a similar dosing schedule. The wounds were inspected post-operatively for infection.<br>One patient out of fifteen in group one (2.2%) and nine patients out of fifteen (60%) in group two (placebo) became infected. The overall infection rate was 33.3%. There was a statistically significant difference in rates of infection between the two groups (p $<$ 0.01). Antibiotic prophylaxis for orthognathic surgical procedures should continue beyond the immediate post-operative period. Five days of antibiotic administration appears to provide adequate coverage.
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12

Chua, Hannah Daile P. "Cleft maxillary distraction versus orthognathic surgery clinical morbidities and surgical relapse /." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31954352.

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13

James, M. A. "In search of the 'real' me : psychological aspects of orthognathic surgery." Thesis, Swansea University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637393.

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A number of studies have shown psychological improvements following orthognathic surgery including body image, self-confidence, mood and sociability (Cunningham et al, 1995). The increased demand for treatment however has not been paralleled with research exploring the <i>dynamic</i> nature of body image, which has largely been ignored. A combination of qualitative and quantitative methodologies sought to achieve a more comprehensive understanding of body image. Patients were recruited from the Oral and Maxillofacial Unit in Swansea. Pre- and post-operative patients, clinical (wisdom teeth removal) and non-patient controls completed measures of body image; body dysmorphic disorder; self-consciousness; self-esteem; and social support. Results showed significant improvements in body image distress and self-consciousness, particularly in relation to other people. More normative concerns of weight and body shape became salient to individuals’ body image. Interpretive Phenomenological Analysis of five women undergoing orthognathic surgery was employed in Study 2. Emergent themes from interviews at 1-4 weeks before surgery, and at three, six, nine and twelve months post-surgery, revealed that living with a dentofacial deformity led to social, affective, behavioural and cognitive restrictions. Post-surgery, individuals experienced a sense of release from these restrictions as body image, self-confidence, affect and sociability improved. Positive feedback from other played a pivotal role in improving body image, self-perceptions and a more normative body image was emerging. In a repeated-measures design, participants in Study 3 completed measures of beliefs about appearance; body image dissatisfaction; fear of negative evaluation; anxiety, depression; and self-esteem, at pre-surgical, and at three and six month post-surgical periods. Self-esteem, anxiety, fear of negative evaluation and body image significantly improved following surgery.
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14

Wu, Yuen-fan Lina, and 胡婉芬. "Psychological adjustment of patients with dentofacial deformity beforeand after orthognathic surgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47849381.

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Dentofacial deformities have an adverse impact on functional as well as psychological wellbeing. Being highly visible, they may lead to a host of psychological problems particularly in youths and young adults as concerns about bodily identity and integrity are likely to be most prominent. Body image and self-esteem have been noted to play an important role in adjusting to disfigurement. Those who opted for corrective orthognatic surgery with realistic expectations were found to have a higher level of satisfaction with the outcome of the surgery. In contrast, undue and unrealistically positive aspirations towards the surgery are implicated in increased post-operative psychological difficulties. This study aimed to systematically document the variability of psychological adjustment and study the predictors of well-being in individuals with dentofacial deformity after orthognathic surgery. Seventy patients pending to go through orthognathic surgery were recruited from a university based dental hospital. Assessments of the patients’ overall psychological condition and adjustment towards their dentofacial deformity were conducted with standardized questionnaires and compared with similar assessment conducted with control subjects. The patients’ motivations for orthognathic surgery, psychological well-being, as well as expectations on the outcomes of surgery were studied through individually conducted psychological assessment interviews. Patients were re-assessed at 6 and 12 months after surgery on their level of satisfaction toward the outcome of surgery as well as to gauge possible changes in their psychological condition. There was no excess of significant psychopathology in patients with dentofacial deformity compared to the normal control group. However, as predicted, people with dentofacial deformity were more dissatisfied with their facial attractiveness. They also have more problems in interpersonal sensitivity. In the patient group, functional impairment or disability was a lesser concern compared to body image and presentation. Improvement of physical attractiveness was a strong underlying motivation for treatment. Longitudinal data on patients’ level of satisfaction with the treatment outcomes and perceived benefits associated with the improved facial esthetics will be further analyzed in the light of their underlying psychological vulnerabilities or resilience. The results are expected to cast light on factors that may affect patients’ satisfaction with the treatment. The results of the study confirmed that dissatisfaction with facial appearance prompted acceptance of surgery despite its associated discomfort and hazards. The findings of the study are expected to be useful in better informing clinical psychological interventions with aims of enhancing adjustment and forestalling psychological morbidity through early intervention with individuals coping with facial disfigurement.<br>published_or_final_version<br>Psychiatry<br>Doctoral<br>Doctor of Philosophy
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15

Ramirez, Eusebio, and Jesper Elenius. "Indications and Frequency of Orthognathic Surgery in Sweden – a Questionnaire Survey." Thesis, Umeå universitet, Tandläkarutbildning, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-97848.

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Orthognathic surgery is today a standard procedure for improving the intermaxillary relationship by moving either one or both jaws surgically. However, statistics for frequency and indication for orthognathic surgery in Sweden are today non-existent. The purpose of the study is to examine indications, frequency and surgical techniques for orthognathic surgery performed in Swedish Oral and Maxillofacial Surgery (OMFS) clinics. A questionnaire survey was performed on all Swedish OMFS clinics for the year 2011 to identify gender and age of the patients, surgical techniques, indications, frequency of operations and whether patients underwent one- or two-jaw surgery. A total of 47 out of 50 clinics responded to the survey. According to it, 894 patients were treated with orthognathic surgery. Slightly more women underwent orthognathic surgery than men and 91% of the patients were 26 years or younger. The most common indication was functional and the most common main jaw discrepancy aimed to correct was of sagittal nature. The survey shows great discrepancies between the counties concerning one- vs. two-jaw surgery. The results regarding frequency, age and gender distribution in orthognathic surgery was somewhat expected. However, the spread in frequency regarding one- vs. two-jaw surgery between the counties is concerning. The main indication for performing orthognathic surgery in Sweden is by far functional but there is reason to suggest that aesthetic indication is not negligible.
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16

Pozzer, Leandro Souza 1986. "Avaliação mecânica da fixação da osteotomia Le Fort I com placas de avanço pré dobradas e miniplacas convencionais tipo "L" dobradas manualmente = Mechanical evaluation of Le Fort I osteotomy using prebent advancement plates and conventional "L" miniplate fixation hand bent." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289414.

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Orientador: José Ricardo de Albergaria Barbosa<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-28T00:10:07Z (GMT). No. of bitstreams: 1 Pozzer_LeandroSouza_D.pdf: 8293531 bytes, checksum: 4e4d7f9683c4cd7bf39fd5b3c7755600 (MD5) Previous issue date: 2015<br>Resumo: A cirurgia ortognática é o procedimento cirúrgico mais utilizado para correções das deformidades dentofaciais. Para excessos ou deficiências maxilares o tipo de osteotomia mais utilizado é a osteotomia Le Fort I. Neste trabalho comparamos dois métodos de fixação da maxila após a osteotomia Le Fort I para avaliar a resistência mecânica entre placas de avanço pré-dobradas e miniplacas convencionais tipo "L", ambas do sistema 1,5mm com parafusos de 5mm de comprimento (ENGIMPLAN, Rio Claro/SP/Brasil). Para esse estudo foi desenvolvido um estudo mecânico em réplicas de terço médio da face em resina de poliuretano com a maxila cortada simulando a osteotomia Le Fort I (Nacional Ossos ¿ Jaú/SP/Brasil). Após um avanço de 5mm, dez réplicas de terço médio da face de poliuretano com osteotomia Le Fort I foram separados em 2 grupos (5 modelos em cada grupo), de acordo com a técnica de fixação. Grupo I - 2 placas de avanço pré-dobradas fixas no pilar canino (n=5) e grupo II - 4 miniplacas convencionais tipo "L" dobradas manualmente, sendo 2 placas fixadas no pilar canino e 2 placas fixadas nos pilares zigomáticos, (n=5). As amostras foram acopladas a um suporte metálico especialmente desenvolvido para o teste e foram posicionadas na máquina de ensaio universal Instron (modelo 4411, Norwood/USA) e submetidas a uma carga linear axial na linha média entre os incisivos centrais com velocidade de 1 mm/min, até o deslocamento em 3mm. Os dados obtidos em newtons (N) foram computados pelo software Bluehill 2 (2004) interligado à Instron e então foram submetidos à análise estatística pelo software SPSS/PC 20.0 (Chicago, USA) e foi realizado o teste t para amostra independentes (ANOVA) e o limite de significância estatística foi p<0,05. Dessa forma, o grupo II (placas convencionais tipo L) apresentou maior resistência estatisticamente significativa (p = 0,003), quando comparado ao grupo I (placas de avanço pré-dobradas). Sendo assim, o sistema de fixação com miniplacas convencionais tipo L" promoveu uma melhor estabilidades dos segmentos em comparação com o sistema de placas de avanço pré-dobradas, quando submetido a uma carga axial linear na linha média dos incisivos centrais<br>Abstract: The orthognathic surgery is the most common procedure realized to treat the dentalfacial deformities. For excess or deficiencies of the maxila the most common is the Le Fort I osteotomy. In this study we compared two fixation methods of the maxila after Le Fort I osteotomy to evaluate the mechanical resistence between advancement pre bent plates and conventional "L" miniplates, both of them of the 1.5mm system and screws with 5mm of length (ENGIMPLAN, Rio Claro/SP/Brasil). For this was developed a mechanical study using midface poliurethane replicas with the maxilla cut simulating Le Fort I osteotomy (Nacional Ossos ¿ Jaú/SP/Brasil). After the maxillary advancement of 5mm, ten midface poliurethane replicas with Le Fort I osteotomy were split into two groups (5 poliurethane midface replicas in each group), according to the fixation technique: Group I ¿ 2 advancement pre bent plates at the canine buttress (n=5) and the group II ¿ 4 conventional "L" miniplates, 2 "L" miniplates at the canine buttress and other 2 "L" miniplates at the zygomatic buttress (n=5). The samples were adapted to a metalic support specially developed for this study and than were positionated at the universal testing machine INSTRON (model 4411, Norwood/USA) and than they were submitted to an axial load in the midline between the upper central incisors with 1mm/min speed, until 3mm of displacement. The data were obtained in newtons (N) and they were processed using the Bluehill 2 (2004) software connected to Instron machine and than the results were submitted do the statistical analysis usign the SPSS/PC 20.0 software (Chicago/USA) and was done the t test for independent sample (ANOVA) and the statistical signifcance limit was p<0,05. Thereby, the group II (conventional "L" miniplates) presented major mechanical resistence statistically significant (p=0,003), when compared to the group I (advancement pre bent plates). Thus, the conventional "L" plates fixation system promoted better stability of the maxila in comparison with advancement pre bent plates when submitted to an axial load in the midline of the central upper incisors<br>Doutorado<br>Cirurgia e Traumatologia Buco-Maxilo-Faciais<br>Doutor em Clínica Odontológica
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17

Lee, Su-ying Alice. "An acoustic and perceptual analysis of /s/ before and after orthognathic surgery." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/hkuto/record/B3620996X.

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Thesis (B.Sc)--University of Hong Kong, 1999.<br>"A dissertation submitted in partial fulfilment of the requirements for the Bachelor of Science (Speech and Hearing Sciences), The University of Hong Kong, May 14, 1999." Also available in print.
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18

Bergström, Maja, and Hala Al-Dory. "Virtual Surgical Planning in Orthognathic Surgery, Mandibular Reconstruction, and Dental Implant Treatment." Thesis, Umeå universitet, Institutionen för odontologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-143427.

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Virtual surgical planning (VSP) has the potential to make the work process of oral and maxillofacial surgery more efficient both in terms of performance and cost.  This study aims to investigate how VSP is used among oral and maxillofacial surgery clinics in Sweden, and to analyse VSP with regard to accuracy, healing, patient communication, and overall operative time.  A questionnaire was sent to all (n = 34) oral and maxillofacial surgery clinics in Sweden, concerning their knowledge and practice of VSP. A literature review was also carried out to compare the results from clinics in Sweden with the general view.  94 % of the oral and maxillofacial surgery clinics participated in the study, and all respondents affirmed knowledge of VSP. While 65 % recognise a need for VSP in their work, only 42 % utilise it. The main obstacles reported were economy, training, and availability. This was in high accordance with the literature review. The review also concluded that VSP increased accuracy, reduced planning time, decreased blood loss, and lowered the need for reoperations.  The presented study shows that VSP is beneficial both pre- and intra-operatively in orthognathic surgery, mandibular reconstruction and implant placement. Accuracy, planning, and patient communication are improved with VSP, both according to studies and questionnaire respondents. However, healing, overall operative time, and cost-benefit did not show strong evidence of improvement with VSP, which might explain the contrasted responses in the questionnaire on these subjects.
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19

Hajeer, Mohammad Younis. "3D soft-tissue, 2D hard-tissue and psychosocial changes following orthognathic surgery." Thesis, University of Glasgow, 2003. http://theses.gla.ac.uk/3126/.

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A 3D imaging system (C3D®), based on the principles of stereophotogrammetry, has been developed for use in the assessment of facial changes following orthognathic surgery. Patients’ perception of their facial appearance before and after orthognathic surgery has been evaluated using standardised questionnaires, but few studies have tried to link this perception with the underlying two-dimensional cephalometric data. Comparisons between patients’ subjective opinions and 3D objective assessment of facial morphology have not been performed. Aims: (1) To test the reliability of the 3D imaging system; (2) to determine the effect of orthognathic surgery on the 3D soft-tissue morphology; (3) to assess skeletal changes following orthognathic surgery; (4) to evaluate soft-tissue to hard-tissue displacement ratios; (5) to ascertain the impact of orthognathic surgery on patients’ perception of their facial appearance and their psychosocial characteristics, (6) to explore the dentofacial deformity, sex and age on the psychosocial characteristics; (7) to evaluate the extent of compatibility between the cephalometric and the three-dimensional measurements and (8) to determine if the magnitude of facial soft-tissue changes affects the perception of facial changes at six months following surgery. Results and Conclusions: C3D imaging system was proved to be accurate with high reproducibility. The reproducibility of landmark identification on 3D models was high for 24 out of the 34 anthropometric landmarks (SD£0.5 mm). One volumetric algorithm in the Facial Analysis Tool had an acceptable accuracy for the assessment of volumetric changes following orthognathic surgery (mean error=0.314 cm3). The error of cephalometric method was low and the simulation of mandibular closure proved to be reproducible. 2D soft-tissue measurements were compatible with 3D measurements in terms of distances, but angular measurements showed significant differences (p<0.05).
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Soncul, Murat. "Evaluation of facial soft tissue changes and surgical outcome of orthognathic surgery." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394980.

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21

Gray, Sarah Lauren. "Down Regulation of Muscle Strength Genes in Orthognathic Surgery Patients with Asymmetry." Master's thesis, Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/316137.

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Oral Biology<br>M.S.<br>Objective: Genetic loci for ATP2A2 kinase, NUAK1, and phosphatase PPP1CC are associated with skeletal muscle strength phenotypes. ATP2A2 is a calcium ion transport ATPase in sarcoplasmic reticulum that is predominantly expressed in cardiac and slow-twitch fibers. NUAK1, an AMP-activated protein kinase, and PPP1CC, a subunit of protein phosphatase 1, are involved in glycogen metabolism during skeletal muscle contraction. The aim of this study is to investigate whether these genes are associated with masseter muscle composition and function in the development of skeletal malocclusion. Methods: A total of 56 orthognathic surgery patients were classified as having skeletal Class I, Class II, or III sagittal malocclusions with normal, open, or deep bites vertically, with or without facial asymmetry. Masseter muscle samples were collected during the mandibular osteotomies, frozen, and sent to the Kornberg School of Dentistry. Tissue from eleven patients was used for gene expression analysis on Affymetrix HT2.0 microarray chips and a principle components analysis. Then, these plus an additional 45 masseter samples were used for quantitative RT-PCR. Expression data for the three genes of interest were evaluated in the microarray and corroborated and expanded upon with RT-PCR data. ANOVA and unpaired t-tests were performed to determine correlations between ATP2A2, NUAK1, and PPP1CC expression levels and vertical and sagittal malocclusion classifications. Additional ANOVA and unpaired t-tests were performed to determine correlations between ATP2A2 expression level and signs and symptoms of temporomandibular disorder (TMD) with and without pain and facial asymmetry, and relative to the expression levels of a second gene associated with muscle strength phenotypes (ACTN3). Finally, Kendall Tau analyses were performed to compare ATP2A2 expression levels in subjects grouped by malocclusion classification to masseter muscle composition, including mean fiber area (MFA) and mean percent occupancy (MPO) of each fiber type. Results: Principle component analysis revealed two patients with genetic expression levels that deviated from the group. These were the only patients diagnosed with facial asymmetry. Microarray data showed that in these patients ATP2A2 and PPP1CC were significantly decreased. NUAK1 was decreased to a lesser extent. Also, among other genes in the same functional categories, ATP2A1 expression was -30.45 fold (P<6.11X10-6) and PPP3CC expression was -2.96 fold (P<2.03X10-5) in the patients with facial asymmetry. RT-PCR results showed NUAK1 and PPP1CC were differentially expressed at lower, but not statistically significant levels in subjects with craniofacial asymmetry. However, RT-PCR did verify that ATP2A2 expression is down regulated in subjects with mild to severe forms of asymmetry as compared to subjects with facial symmetry (p=0.022). ANOVA and unpaired t-test analyses illustrated that there was no significant differences in ATP2A2 expression in patients with different vertical, saggital, or combined vertical/sagittal malocclusion diagnoses. There was a significant association between the lateral differences in ATP2A2 expression, between right- and left-sided masseter biopsies within the same individual, in subjects with Class III malocclusions with different vertical diagnoses. Here, lateral differences were greatest in open bite, intermediate in deep bite, and lowest in normal Class III subjects. Kendall tau analyses were performed to compare ATP2A2 expression levels and masseter composition (MFA/MPO of type I, hybrid, and type II fibers) in all subjects, subjects with Class II malocclusions, and subjects with Class III malocclusions. Regardless of sagittal malocclusion, all subjects showed a negative correlation with type IIA MPO that was highly significant (r=-0.46; p=0.004). Also, ATP2A2 associations in Class II subjects were positive with type I MFA (r=0.36; p=0.04) and negative with type IIA MPO (r=-0.59; p=0.001). Correlations for Class III subjects were typically negative and not significant. Also, Kendall tau correlations were performed to compare ATP2A2 expression with the composition of each fiber type in patients grouped by both sagittal and vertical malocclusion classification. These found decreased type IIA fiber MPO correlated significantly (p = 0.024) with increased relative ATP2A2 expression in subjects with Class II, normal bite malocclusions (n = 6, R2 = 0.8127). Finally, ATP2A2 expression was not associated with most phenotypic traits exhibited by the surgery subjects such as presence of signs/symptoms of TMD with and without pain and facial asymmetry. However there was an association between decreased lateral differences in ATP2A2 expression in subjects with asymmetry with the TC ACTN3 genotype as compared to subjects with the TC ACTN3 genotype and facial symmetry. Conclusions: ATP2A2 promotes calcium transport in slow twitch and cardiac muscle contraction-relaxation cycling. Decreased expression of this gene in patients with asymmetries suggests that down regulation of the calcium handling capacities of muscle fibers may influence the development of abnormal craniofacial phenotypes. Both NUAK1 and PPP1CC are thought to play metabolic regulatory or responsive roles to muscle contraction. Decreased expression of these genes may accompany alterations of fiber-type form and metabolic properties to adversely affect jaw development. Additionally, ATP2A2 correlations indicate that this calcium channel protein may be important for type I fiber function, but not type IIA in masseter muscle from Class II subjects, suggesting a functional influence on malocclusions. ATP2A2 does not appear to function differentially in fiber types that influence development of Class III malocclusion. Further studies with more subjects are needed to increase experimental power.<br>Temple University--Theses
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22

Chang, Michael K. "Three-dimensional conebeam CT analysis of pharyngeal airway changes after orthognathic surgery." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1465479.

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23

Chow, Lop-keung Raymond. "Clinical morbidity of resorbable plates and screws for internal fixation in orthognathic surgery." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31954285.

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Montini, Reid W. "Perceptions of orthognathic surgery patients' change in profile a five year follow-up /." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0010492.

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Thesis (M.S.)--University of Florida, 2005.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 30 pages. Includes Vita. Includes bibliographical references.
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Chow, Lop-keung Raymond, and 周立強. "Clinical morbidity of resorbable plates and screws for internal fixation in orthognathic surgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31954285.

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Mattila, Jessica, and Cecilia Nordqvist. "Experience and Implementation of Virtual Surgical Planning in Orthognathic Surgery in Northern Sweden." Thesis, Umeå universitet, Tandläkarutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-178801.

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ABSTRACT Background: Two-dimensional surgical planning does not adequately show the 3D aspect, which is important to assess in the planning of orthognathic surgery (OGS). In the last decade, 3D virtual surgical planning (VSP) has become an advantageous method and may replace conventional planning. Aim: To determine if the experience and implementation of VSP in OGS among professionals in oral and maxillofacial surgery in northern Sweden differs from the literature on the subject. Methods: A questionnaire was created for evaluation of the experience and implementation of VSP and a literature search was conducted through PubMed. Results: Fourteen of 17 respondents answered. Only fifty percent used VSP, even though all respondents were familiar with it. A bigger proportion of respondents would use VSP, but availability and lack of training prevented use. A sample of 33 articles were collected and described 1107 patients undergoing OGS, of which 1083 patients had undergone OGS with incorporation of VSP. Sixty-eight percent underwent bimaxillary surgery, 17 % maxillary surgery and 15 % mandibular surgery. Additionally, 169 patients were treated with genioplasty as well. Conclusion: The experience and implementation of VSP in northern Sweden are both in accordance and discordance with the literature. VSP has the advantage of accurate hard tissue prediction, but the literature describes the need of improvement concerning soft tissue imaging and postoperative assessment in VSP. More studies evaluating the accuracy and reliability of VSP software are needed. Disadvantages of VSP need to be resolved before VSP can replace conventional planning.
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Dragon, Carolyn Bradford. "Let’s Face It: The effect of orthognathic surgery on facial recognition algorithm analysis." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5778.

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Aim: To evaluate the ability of a publicly available facial recognition application program interface (API) to calculate similarity scores for pre- and post-surgical photographs of patients undergoing orthognathic surgeries. Our primary objective was to identify which surgical procedure(s) had the greatest effect(s) on similarity score. Methods: Standard treatment progress photographs for 25 retrospectively identified, orthodontic-orthognathic patients were analyzed using the API to calculate similarity scores between the pre- and post-surgical photographs. Photographs from two pre-surgical timepoints were compared as controls. Both relaxed and smiling photographs were included in the study to assess for the added impact of facial pose on similarity score. Surgical procedure(s) performed on each patient, gender, age at time of surgery, and ethnicity were recorded for statistical analysis. Nonparametric Kruskal-Wallis Rank Sum Tests were performed to univariately analyze the relationship between each categorical patient characteristic and each recognition score. Multiple comparison Wilcoxon Rank Sum Tests were performed on the subsequent statistically significant characteristics. P-Values were adjusted for using the Bonferroni correction technique. Results: Patients that had surgery on both jaws had a lower median similarity score, when comparing relaxed expressions before and after surgery, compared to those that had surgery only on the mandible (p = 0.014). It was also found that patients receiving LeFort and bilateral sagittal split osteotomies (BSSO) surgeries had a lower median similarity score compared to those that received only BSSO (p = 0.009). For the score comparing relaxed expressions before surgery versus smiling expressions after surgery, patients receiving two-jaw surgeries had lower scores than those that had surgery on only the mandible (p = 0.028). Patients that received LeFort and BSSO surgeries were also found to have lower similarity scores compared to patients that received only BSSO when comparing pre-surgical relaxed photographs to post-surgical smiling photographs (p = 0.036). Conclusions: Two-jaw surgeries were associated with a statistically significant decrease in similarity score when compared to one-jaw procedures. Pose was also found to be a factor influencing similarity scores, especially when comparing pre-surgical relaxed photographs to post-surgical smiling photographs.
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Panula, K. (Kari). "Correction of dentofacial deformities with orthognathic surgery:outcome of treatment with special reference to costs, benefits and risks." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514269934.

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Abstract Considerable amounts of research have been done on various aspects of orthognathic surgery during its short history. Nevertheless, there are no comprehensive publications on the cost-risk-benefit analysis of the entire process of orthognathic surgery. The purpose of the present study was to evaluate the psychosocial and biophysiological outcomes of orthognathic surgery with special reference to complications and financial costs. The study series consisted of patients referred for consultations and treatment of dentofacial deformities and involved a total of 953 patients and 20 controls. Both prospective clinical follow-up examinations with measurements of various clinical parameters and retrospective assessments of radiographs and patient records were included. Functional and pain-related reasons were found to motivate patients to seek orthognathic surgery, and this impression was confirmed by the clinical findings. The great majority of the subjects examined had signs and symptoms of temporomandibular disorders (TMD). The significance of facial appearance for the motivation to seek treatments seemed to play a lesser role compared to most earlier studies. Most of the patients felt that their expectations had been fulfilled by the treatment, and despite the potential risks involved, the overall complication rate in orthognathic surgery was very low. The most usual problem was neurosensory deficit of the inferior alveolar nerve. TMD patients with skeletal Class II non-open bite dentofacial deformity seem to have the greatest probability to benefit from orthognathic surgery, especially if their TMD is mostly of muscular origin. Pain in the face and headache improved significantly. The outcomes were more variable when the TMD mainly originated from internal derangements. In these cases, the individual outcome of treatment is more difficult to predict, and conservative treatment methods should probably be tried first. The orthognathic surgery of patients with non-open bite skeletal Class II dentofacial deformity is also cost-effective due to the low complication rate and the low cost, since sagittal ramus osteotomy is often sufficient treatment. However, there must be weighty grounds for orthognathic surgery of skeletal open-bite deformities due to their greater risk for relapse and condylar resorption. The high expenses of their treatment also result in a poor cost-effectiveness ratio.
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夏炯 and Jiong James Xia. "Three-dimensional surgical planning and simulation system for orthognathic surgery in virtual reality environment." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B3123950X.

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Watt, E. N. "A DVD on orthognathic surgery : a randomised controlled trial assessing patients' knowledge and satisfaction." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3006573/.

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Title: BOS Orthognathic DVD: RCT assessing patients’ knowledge and satisfaction Objectives: To compare patients’ knowledge of orthognathic treatment and satisfaction with their multi-disciplinary clinic consultation, after receiving information in a standard format versus standard format plus BOS Orthognathic DVD. Design: Multi-centred, randomised controlled trial. Setting: Multi-disciplinary orthognathic clinics at four hospitals in Merseyside, UK. Participants and Methods: 106 participants, age > 16 years, attending their first multi-disciplinary orthognathic clinic, were given information on orthognathic treatment in either the standard format – verbal and written or the standard format plus the BOS Orthognathic DVD. Primary outcome measures were participants’ knowledge of orthognathic treatment and satisfaction with their multi-disciplinary clinic consultation and information provided. Validated knowledge questionnaires were given prior to the multi-disciplinary clinic consultation and 4-6 weeks later. Satisfaction was assessed from participants’ response to 16 questions using visual analogue scale. Results of knowledge scores were analysed using ANCOVA at p < 0.05, and satisfaction using non-parametric Mann Whitney Wilcoxon test. Results: Knowledge scores improved from baseline in both groups. Baseline knowledge had a statistically significant effect on participants’ follow-up score. No significant difference in knowledge score was found between groups at follow-up once the baseline score had been accounted for. No difference in general satisfaction was found between groups. However, satisfaction with the DVD was significantly less than general satisfaction (p=0.015). Conclusions: There was no difference in participants’ knowledge of orthognathic treatment or satisfaction when given information in the standard format or standard format plus the BOS Orthognathic DVD.
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Foley, Bryan Francis. "IDENTIFICATION OF POTENTIAL GENETIC MARKERS OF FACIAL ASYMMETRY AND TMD IN ORTHOGNATHIC SURGERY PATIENTS." Master's thesis, Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/286577.

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Oral Biology<br>M.S.<br>Temporomandibular disorders (TMD) are comorbid conditions. Most are related to anxiety-induced muscular pain, but some are associated with facial asymmetry resulting from condylar resorption (CR) or condylar hyperplasia (CH). The etiology of the most common forms of CH and CR are still unknown. CR can be caused by rheumatoid arthritis (RA) or more commonly osteoarthritis (OA) of the TMJ, and inflammatory mediators have been previously implicated. Previous studies have identified pain/inflammatory genes related to chronic TMD while others have demonstrated potential genetic markers for RA. Similarly, genome-wide association (GWA) studies have identified genes associated with height, some of which may participate in craniofacial growth, CH, and the development of asymmetry. Masseter muscle is frequently involved in TMD of muscular origin, and left/right fiber-type differences have been previously found in subjects with facial asymmetry. A human transcriptome microarray was used to evaluate whether genes involved with height, pain, or inflammation were differentially expressed in masseter muscle from facially asymmetric patients with and without TMD. This study evaluated orthognathic surgery patients with varying skeletal malocclusions, including subjects with and without facial asymmetry and TMD (n= 93). Masseter muscle samples were collected from ten orthognathic surgery patients treated to correct skeletal malocclusions. Two of whom were classified with facial asymmetry with or without TMD, with one of the two showing positive evidence of CR. Samples were disrupted in QIAzol Lysis Reagent, RNA was isolated using a Qiagen miRNeasy Mini Kit according to the manufacturer's instructions, and quality of the total RNA was tested by Agilent Bioanalyzer and Nanodrop spectrophotometry. Samples were used for quantitative Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) and protocols for microarray analysis were conducted as described in the Ambion WT Expression Manual and the Affymetrix GeneChip Expression Analysis Technical Manual. Principal Components Analysis (PCA) was completed to detect fold-changes for each transcript to determine differences in global gene expression between the two asymmetric and eight remaining subjects. To find differentially expressed transcripts step-up t-tests were performed to correct for false discovery rate (FDR) comparing the two asymmetric samples to the eight symmetric samples. Differences were considered significant if step-up p-values were ±2 between groups. This study evaluated 847 height-related genes and 551 genes associated in pain/inflammatory processes. Genes of interest were determined a priori from GWA studies and the Algynomics Pain Research Panel v.2.0 partially derived from the Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) study. Two hundred and eight transcripts of 847 height associated genes and 132 of 551 pain/inflammatory genes were significant for expression (P±2.0 fold differences in facial asymmetry and/or TMD specimens. Among genes specifically reported to be associated with pain/inflammation, NPY5R (+2.11 fold), GABRA6 (+2.14 fold), CACNA2D1 (-12.51 fold) and EREG (+2.12 fold) showed significantly different (P<0.001) expression levels in the two asymmetric versus the remaining eight symmetric patients. CACNA2D1 expression was significantly increased in symmetric male subjects versus symmetric females (P < 0.05) as well as in asymmetric females versus asymmetric males (P < 0.05). CACNA2D1 expression was also significantly increased in symmetric male subjects versus symmetric females (P <0.05) and was differentially expressed at lower levels, however not significantly, in asymmetric males (p = 0.51). Based on the results collected, the following conclusions were drawn. These methods provide a novel approach to study TMD and/or facial asymmetry in human subjects. To our knowledge, this is the first study to demonstrate that significant expression variation in human height genes may contribute to facial asymmetry with or without TMD, possibly through decreased expression of CACNA2D1. These data suggest TMD patients with facial asymmetry associated with condylar resorption may show significant differential expression of certain inflammatory marker genes such as EREG and CACNA2D1. These data support that gender may play a key role in the development of TMD, possibly through increased CACNA2D1 expression providing protective effects in TMD-free males but deleterious effect in females with TMD. These results support previous findings of pain/inflammatory genes associated with TMD derived from muscular pain. Further studies are needed to understand the genetic contributions to TMD, which may play an important role in future clinical intervention.<br>Temple University--Theses
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Chua, Hannah Daile P. "Distraction osteogenesis versus orthognathic surgery which is better for cleft lip and palate patients? /." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41758195.

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Tucker, Gary Roderick Jr Phillips Ceib. "Relationship of the mandibular canal and fixation placement to sensory alteration following orthognathic surgery." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2449.

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Thesis (M.S.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Sep. 3, 2009). "... in partial fulfillment of the requirements for the Master of Science in the School of Dentistry Orthodontics." Discipline: Orthodontics; Department/School: Dentistry.
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Xia, Jiong James. "Three-dimensional surgical planning and simulation system for orthognathic surgery in virtual reality environment /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20377824.

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Zablocki, Destinee Elizabeth. "Differential Expression of Calsarcin Genes in Orthognathic Surgery Patients with ACTN3 R577X Gene Deviations." Master's thesis, Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/405298.

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Oral Biology<br>M.S.<br>Objective: Malocclusion is a complex musculoskeletal trait, with muscle playing an integral role in vertical facial development. A single nucleotide polymorphism (SNP) produces the R577XX nonsense mutation in the alpha-actinin-3 (ACTN3) gene, creating a stop codon and loss of its protein. With loss of ACTN3, alpha-actinin-2 (ACTN2) is upregulated. Calsarcins, known inhibitors of calcineurin activation, preferentially bind ACTN2 leading to a surge in free calcineurin. The increase in calcineurin activity produces the phenotypic shift of fast muscle fibers toward the slow myogenic program seen in the ACTN3 null genotype (Seto et al., 2013). Here, we have tested whether calsarcin gene expression is affected by ACTN3 genotypes in human masseter muscle. Methods: Subjects undergoing orthodontic treatment and orthognathic surgery were recruited from the University of Lille, Department of Oral and Maxillofacial Surgery in Northern France. During the bilateral sagittal split osteotomy, masseter muscle samples were collected from the discarded section of deep anterior superficial masseter muscle, snap frozen, and shipped to Dr. Sciote’s lab at Temple University. RNA from masseter muscle samples was isolated from 41 subjects using TRIzolTM reagent. MYOZ gene expression was quantified by RT-PCR using an adult skeletal muscle reference standard (commercially prepared skeletal muscle RNA; Ambion, Inc), and individual primer-probe sets for MYOZ1, MYOZ2, MYOZ3, and HPRT1 (utilized for normalization of data). ANOVA and unpaired t-tests were used to determine the significance of expression differences between MYOZ genes and by ACTN3 R577X genotypes, as well as by malocclusion classes. Pearson analyses were used to determine correlations between MYOZ expression and fiber type mean percent occupancies. Results: The main aim of this project was to determine whether expression of the three calsarcin genes, MYOZ1, 2, and 3, differs between subjects with RR, RX and XX genotypes for the ACTN3 gene, as well as between sagittal and vertical classes of malocclusion, asymmetries and TMD. Differences were found for MYOZ3 expression where relative quantities in males, but not females, decreased progressively from the ACTN3 RR, to RX, and XX genotypes. Among subjects with the RX genotype, expression differed significantly between males and females by an unpaired t-test. A statistically significant difference was detected between MYOZ2 and Class II, Class III malocclusions (p=0.05). Sagittal differences were compared further by ANOVA analyses with a statistically significant difference detected for MYOZ3 with a probability of 0.02. Correlation analyses comparing fiber type mean % occupancy with calsarcin gene expression revealed a significant positive relationship between MYOZ2 and type I (slow-twitch) fibers. Correspondingly, a significant correlation of MYOZ2 expression with type IIA and IIX (fast-twitch) fibers was negative. Conclusions: The greatest relative quantity of RNA for the three calsarcin genes was found in MYOZ3, suggesting more calsarcin-3 may be needed in masticatory muscle structure and function than other calsarcin isoforms. Alternatively, high expression of MYOZ3 in the masseter samples may indicate that there are relatively greater amounts of that isoform in cranial muscle than in the limb skeletal muscle standard used in these studies. Also, relative quantities of MYOZ3 expression in males decreased progressively from the ACTN3 RR, to RX, and XX genotypes. While this data may suggest that the ACTN3 R577X polymorphism may affect MYOZ3 expression in males of the malocclusion patient population, an increased sample of male subjects would be needed to determine if this trend has true significance. Expression of MYOZ2 (calsarcin-1) was strongly correlated with slow fiber-type occupancy in masseter muscle of our patient population. The muscle-specific expression of each calsarcin may lend to the understanding of this result. MYOZ2 is the only isoform found in both cardiac muscle and slow-twitch skeletal muscle, while MYOZ1 and MYOZ3 are both found in skeletal muscle with a predilection towards fast-twitch skeletal muscle (Frey et al., 2004).<br>Temple University--Theses
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Gaetti-Jardim, Ellen Cristina [UNESP]. "Análise da perda volêmica em pacientes submetidos a expansão rápida de maxila assistida cirurgicamente." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/88933.

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Made available in DSpace on 2014-06-11T19:23:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-02-11Bitstream added on 2014-06-13T18:17:18Z : No. of bitstreams: 1 jardim_ecg_me_araca.pdf: 229259 bytes, checksum: 15c9095c65db3dcdffe47d437cca73fa (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>As cirurgias ortognáticas são procedimentos executados com frequência e complicações como lesões arteriovenosas ou mesmo pelo tempo cirúrgico, podem ocasionar hipovolemia. A necessidade de reposição do volume sanguíneo por meio da infusão de soluções cristalóides, colóides ou até a transfusão de sangue é sempre considerada. Assim, propôs-se neste estudo quantificar a perda sanguínea, bem como avaliar a necessidade da transfusão sanguínea em 19 pacientes submetidos à expansão rápida de maxila assistida cirurgicamente. Foram avaliados os valores de pressão arterial média, tempo de procedimento cirúrgico, gênero, perda volêmica intra-operatória e classificação ASA. Pode-se concluir que a hipovolemia e a requisição de transfusão de sangue nestas cirurgias foram pequenas, entretanto, os profissionais devem sempre estar atentos quanto ao tempo cirúrgico e ao aprimoramento da técnica cirúrgica<br>Orthognathic surgeries are procedures performed at a frequency quite considerable and now, at the expense of complexity with regard to the complications inherent in the technique, such as arteriovenous injuries or even the time of surgery, can cause a severe hypovolemia. The need for replacement of blood by infusion of crystalloid solutions, colloids or by blood transfusion is always considered. Thus, we proposed this study to quantify the blood loss, and assess the need for blood transfusion in 19 patients undergoing to surgical assisted rapid maxillary expansion. The values of mean arterial pressure, duration of surgery, gender, ASA classification and volume loss. It can be concluded that hypovolemia and the request for blood transfusion in these surgeries were small, however, professionals should always be alert as to the time of surgical procedure and the development of a meticulous surgical technique
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Pereira-Stabile, Cecilia Luiz. "Analise cefalometrica pre-operatoria de pacientes com deformidades dentofaciais classe III submetidos a avanços maxilares." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288773.

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Orientador: Roger William Fernandes Moreira<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-15T00:49:56Z (GMT). No. of bitstreams: 1 Pereira-Stabile_CeciliaLuiz_D.pdf: 1327291 bytes, checksum: 29dbfcc34db77c5a69f4888c91d8a8d0 (MD5) Previous issue date: 2009<br>Resumo: Este trabalho teve como objetivo geral avaliar os diagnósticos cefalométricos préoperatórios de pacientes clinicamente diagnosticados como portadores de deformidades dento-faciais Classe III por deficiência antero-posterior de maxila, que foram submetidos a cirurgias para avanço maxilar por meio de osteotomias Lê Fort I em duas instituições de ensino. Para tanto, foram analisadas as telerradiografias de perfil pré-operatórias imediatas de 50 pacientes submetidos a cirurgias ortognáticas para avanço maxilar, associado ou não a mentoplastia. As telerradiografias foram traçadas manualmente e digitalmente (Dolphin Imaging and Management Solutions, Chatsworth, CA, EUA) e submetidas às análises cefalométricas de McNamara, Steiner e Legan & Burstone, pelo mesmo operador, utilizando material e técnica padronizados, com três repetições de cada análise, gerando um valor médio para cada medida. Os valores obtidos foram tabulados e submetidos a análise estatística usando-se o teste t para uma média (p_0,05) para comparação com os valores norma, e o teste t pareado para comparação entre os métodos manual e digital (p_0,05). Baseado nos resultados obtidos, foram redigidos três artigos científicos abordando diferentes aspectos do estudo, apresentados aqui em três capítulos. O capítulo 1 abrange a análise cefalométrica dento-esqueletal e de tecidos moles, obtida segundo o método manual, que foi confrontada com as normas cefalométricas. O capítulo 2 discorre sobre a inclinação de incisivos, apresentando os resultados obtidos no presente estudo e discute sobre as compensações dentárias e sua importância no planejamento e resultados das cirurgias ortognáticas. No capítulo 3, são apresentados os resultados das análises manual e digital, as quais foram comparadas estatisticamente. Baseado nos resultados obtidos, pode-se concluir que: (1) a análise cefalométrica de pacientes com deformidades Classe III não apresentou correlação com o diagnóstico clínico em grande parte dos parâmetros analisados; (2) a maioria dos pacientes Classe III submetidos a avanços maxilares apresentou descompensação incompleta de incisivos no pré-operatório imediato; (3) a análise cefalométrica digital não apresentou correlação com a análise manual, quando empregada a metodologia descrita.<br>Abstract: The main purpose of this study was to evaluate the preoperative cephalometric diagnoses of skeletal Class III patients, who had been clinically diagnosed as maxillary defficient and undergone maxillary advancements with Le Fort I osteotomies in two teaching facilities. The preoperative lateral cephalometric radiographs of 50 patients treated with maxillary advancements, associated or not with genioplasties, were analyzed. Radiographs were hand traced and digitally traced using Dolphin Imaging 10 (Dolphin Imaging and Management Solutions, Chatsworth, CA, EUA), and McNamara, Steiner and Legan & Burstone analyses were used. The same operator performed all tracings three times to insure consistency and reliability. A mean value of the three tracings resulted for each measurement. The values were statistically analyzed using the t test for a mean (p_0.05) to compare them with the norm values. The paired t test was used to compare manual and digital results (p_0.05). Based on the results, three scientific articles were written, focusing on different aspects of the study and presented here in three chapters. Chapter 1 presents the dental-skeletal and soft tissue analyses obtained from hand tracing and confronted with cephalometric norms. Chapter 2 focuses on incisor inclinations, presenting the results and discussing the importance of dental compensations on treatment planning and outcomes of orthognathic surgery. In chapter 3, manual and digital cephalometric analysis are presented and compared statistically. Based on the results, the conclusions are: (1) cephalometric analysis of patients with Class III dentofacial deformities had no significant correlation with clinical diagnosis for most of the analyzed parameters; (2) most of the Class III patients undergoing maxillary advancements presented incomplete decompensation of incisors in the immediate preoperative radiographs; (3) digital cephalometric analysis had no correlation with manual analysis when the described methodology was used.<br>Doutorado<br>Cirurgia e Traumatologia Buco-Maxilo-Faciais<br>Doutor em Clínica Odontológica
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Giglio, Fernando Paganeli Machado. "Avaliação da aplicabilidade de um padrão cefalométrico norte-americano em pacientes brasileiros submetidos à cirurgia ortognática." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/25/25132/tde-24082007-143929/.

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Estudou-se a aplicabilidade de um padrão cefalométrico norte-americano em pacientes brasileiros submetidos à cirurgia ortognática, por meio da comparação dos traçados cefalométricos pós-tratamento ortodôntico-cirúrgico de 29 pacientes (14 homens e 15 mulheres), que passaram por cirurgia de maxila e mandíbula, com ou sem mentoplastia, com o padrão cefalométrico utilizado como orientação para o planejamento dos casos. Os traçados foram gerados pelo programa Dolphin Imaging 9.0 a partir de telerradiografias em norma lateral digitalizadas, nas quais foram marcados 48 pontos de referência dentários, ósseos e de tecidos moles. Dessa forma, obteve-se 26 grandezas cefalométricas lineares e angulares para posterior comparação com os valores normativos norte-americanos, considerando-se o dimorfismo sexual e as eventuais modificações feitas no planejamento em virtude das necessidades individuais de cada caso e das possíveis diferenças étnico-raciais. Os dados da amostra foram confrontados com o padrão individualmente de maneira descritiva e em conjunto, por meio da comparação das médias e desvios-padrão com o teste \"t\" de Student. Os resultados mostraram que para os homens as médias da amostra foram significantemente diferentes do padrão em apenas cinco das grandezas estudadas, enquanto que para as mulheres, nove apresentaram diferença estatisticamente significativa. No entanto, apesar da similaridade das médias na maioria das medidas em ambos os gêneros, os dados mostraram grandes variações individuais. A análise dos resultados obtidos sugere que o padrão cefalométrico norte-americano estudado é aplicável como referência para o planejamento de casos ortodôntico-cirúrgicos de pacientes brasileiros desde que se atente às variações individuais, caracterizando o planejamento de acordo com as necessidades de cada paciente.<br>It was studied the applicability of a North American cephalometric norm in brazilian patients submitted to orthognathic surgery, through the comparison of the posttreatment cephalometric values of 29 patient (14 men and 15 women), who had bimaxillary surgery, with or without genioplasty, with the cephalometric norm used as orientation for the treatment planning of the cases. The tracings were generated by the program Dolphin Imaging 9.0 from lateral head films that were digitized, in which were marked 48 dental, osseous and soft tissue references points. In that way, it was obtained 26 linear and angular cephalometric measures for subsequent comparison with the normative values, being considered the sexual dimorphism and the eventual modifications done in the planning due to the individual needs of each case and the possible ethnic-racial differences. The data of the sample were confronted individually with the pattern in a descriptive way, and together through the comparison of the averages and standard deviations with the Student \"t\" test. The results showed that for the men the averages of the sample were significantly different from the norm in only five of the studied measures, while for the women, nine cephalometric values presented contrast statistically significant; however, in spite of the similarity of the averages in several measures in both groups, the data demonstrated great individual variations. The analysis of the obtained results suggests that the North American cephalometric norm studied is applicable as reference for the planning of orthognathic surgery in brazilian patients, since it is attempted to the individual variations, characterizing the planning in agreement with the needs of each patient
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Swamy, Charu. "Effects of orthognathic surgery on quality of life compared with non-surgical controls in an American population." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1363795914.

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Salaita, Rashelle. "Effects of Orthognathic Surgery on Quality of Life Compared with Non-Surgical Controls in an American Population: A Cross-Sectional Study." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1424713488.

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Carlotto, Alan Gabriele. "Comparison of Two Survey Instruments Measuring Quality of Life in Pediatric Dentofacial Patients." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1489662161586063.

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42

Frazier, Kirsten. "Prevalence and predictors of adverse effects of medical care in patients with cleft lip and palate undergoing facial bone repairs and orthognathic surgical procedures in the United States." Thesis, University of Iowa, 2019. https://ir.uiowa.edu/etd/6735.

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BACKGROUND AND SIGNIFICANCE: Almost 15% of newborns have congenital anomalies that involve the oral and craniofacial regions, but of these congenital anomalies, cleft lip and palate and craniosynostosis are the most common. It is estimated that the incidence of cleft lip and palate is 0.664 in 1000 live births. These patients commonly have skeletal imbalances of the maxillae and mandible that require surgical and orthodontic correction. Orthodontists and oral surgeons play a critical role in identifying the necessary care and ensuring that the patient receives the best quality of care possible. OBJECTIVES: The objective of the current study is to examine the prevalence of adverse effects of medical care and infectious complications in patients with cleft lip/palate undergoing facial bone repairs/orthognathic surgeries in the United States during the years 2012 to 2014. It will also examine the association between patient/hospital related factors and surgical outcomes (including adverse affects of surgery, incidence of infection, etc.) and how these surgical outcomes impact the hospital costs and length of stay in the hospital. MATERIALS AND METHODS: The Nationwide Inpatient Sample (NIS) is a 20% stratified probability sample of hospitalizations occurring in all acute care hospitals in the United States. It is part of the Healthcare Cost and Utilization Project (HCUP) sponsored by the Agency for Healthcare Research and Quality (AHRQ) [12]. Each hospital in this sample provides information on 20% of hospitalizations occurring during the select years. Hospital stratification is based on multiple hospital-associated variables including: hospital location, geographic region, bed size, teaching status, and ownership/control. Each hospitalization is assigned a sampling weight. Patient-related variables are also provided by the hospitals. In this study, this information is used to provide a nationally representative estimate of all hospitalizations and associated outcomes in the United States from 2012-2014. RESULTS: This study includes all 1,785 patients with cleft lip/palate undergoing facial bone repair/orthognathic surgical procedures in the United States during the study period (2012-2014). These results confirm the hypothesis that there are a combination of patient and hospital related factors that contribute to the occurrence of adverse events and that the occurrence of these events is associated with substantial increases in hospital charges and length of hospital stay. CONCLUSION: These study results are a national representative sample of patients with cleft lip/palate undergoing bony facial repair and orthognathic surgery. They reflect the practice patterns and hospitalization outcomes across the United States. These results can serve as a platform for future prospective controlled studies to examine the risk factors associated with adverse effects of medical care for a wide range of surgical procedures. This information is useful for clinicians, health policy makers, and patients so that they can make informed treatment and policy decisions as well as continue to improve surgical procedures and outcomes.
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43

Conn, Karen Kandel. "Increased Inflammatory Gene Expression in Masseter Muscle of an Orthognathic Surgery Subject with Obstructive Sleep Apnea." Master's thesis, Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/285034.

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Oral Biology<br>M.S.<br>Objective: Obstructive sleep apnea (OSA) is defined by recurrent breathing cessations accompanied by a collapse of the pharyngeal airway. Co-morbid conditions include obesity, cardiovascular disease, diabetes, and in some cases, retrognathia and muscle dysfunction. The latter two conditions may prompt orthognathic correction. Past investigations have shown a genetic association with OSA. Given that masseter muscle influences skeletal malocclusion and is active during OSA, we investigated whether the expression of OSA-associated genes is altered in a Class II open bite OSA subject. Methods: Eleven mandibular advancement surgery patients were classified as skeletal Class II or III and open or deep bite malocclusion, including a Class II open bite patient with OSA. Masseter muscle samples were collected at surgery and frozen. Tissue was used for gene expression analysis on Affymetrix HT2.0 microarray chips and quantitative RT-PCR. Data for ten genes associated with OSA were individually evaluated in the microarray and compared between the OSA patient and eight symmetrical malocclusion subjects. In order to corroborate these expression data, one gene of interest, tumor necrosis factor (TNF), was quantified in the ten malocclusion subjects from the microarray, an OSA subject from the microarray and one additional OSA subject by RT-PCR. Results: Among OSA-associated genes on the microarray, interleukin genes IL1B, IL1R2, IL6 and IL8 were +2.5 to +9.2 fold greater (p < 0.02) and chemokine genes CCL2, CCL3, CCL3L3, CCL4 and CXCR1 were +2.0 to +12.1 fold greater (p < 0.05). Likewise, TNF expression differed significantly in the muscle of the OSA subject (+2.2 fold greater; p < 0.001). By quantitative RT-PCR, TNF expression was significantly greater in malocclusion subjects with OSA compared to those without OSA (p = 0.0004). Conclusions: Our findings support evidence that OSA is an inflammatory disorder, which may elicit hypoxia-induced inflammatory responses believed to promote skeletal muscle dysfunction. Specifically, we report that inflammatory gene expression is significantly increased in masseter muscle in Class II open bite subjects with OSA. In turn, malocclusion may contribute to OSA, which negatively affects masseter function, resulting in exacerbation of both disorders. Because OSA is reported to associate with a polymorphism in the TNF-alpha; gene in children, future studies are needed to test for similar genetic associations in malocclusion subjects with OSA.<br>Temple University--Theses
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44

Méndez-Manjón, Irene. "Three-dimensional evaluation of changes in condylar morphology and position in patients undergoing orthognathic surgery." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/456245.

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La presente tesis doctoral es un compendio de 4 publicaciones sobre los cambios posicionales y morfológicos que ocurren en la articulación temporomandibular tras la realización de cirugía ortognática. Del estudio de campo realizado se concluye que se producen cambios estadísticamente significativos en la posición del cóndilo articular tras la cirugía de avance mandibular. Adicionalmente se valida la utilización de la tomografía computerizada de haz cónico para el estudio morfológico y posicional de la articulación temporomandibular. Esta validación se compone de dos estudios: En el primero se valida la precisión y reproducidibilidad de la superposición tridimensional de los volúmenes obtenidos del CBCT para estudiar los cambios que se producen en cirugía ortognática y más concretamente en la articulación termporomandibular. El segundo estudio, valida la obtención de la reconstrucción tridimensional del volumen de interés ( cóndilo articular) mediante un método de segmentación semiautomática basado en Unidades Hounsfield. Por último se define la realización de una técnica quirúrgica de exéresis intraoral de hiperplasias condilares que es posible gracias sa la aplicación de las técnicas de diagnóstico y planificación tridimensional.
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45

Gordon, Janet. "An analysis of the acceptance of results of orthognathic surgery using a personality profile assessment." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09DM/09dmg6635.pdf.

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"February 1999" Bibliography: leaves 119-138. The results of the study concluded that the identification of the patient's personality profile was unable to predict those patients who would not have a successful perception of the outcome of surgery, mirroring the findings of Pogrel and Scott (1994) who found that it was impossible to identify the 'psychologically bad-risk' orthognathic patient.
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46

Giralt, Hernando María. "Three-dimensional Impact of orthognathic surgery on the upper airway and the apnea-hypopnea index." Doctoral thesis, Universitat Internacional de Catalunya, 2021. http://hdl.handle.net/10803/672154.

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The present PhD investigation is a compendium of five related publications broadening the current state-of-the art and long-term three-dimensional effects of orthognathic surgery on the upper airway (UA) and the sleep-related disorders, such as the Obstructive Sleep Apnea-hypopnea syndrome (OSA). This PhD project, coordinated by Prof. Dr. Federico Hernández-Alfaro and Dr.Adaia Valls-Ontañón at the Universitat Internacional de Catalunya, started in January 2018 as a three-year program, and was granted by the competitive predoctoral fellowship ID: FI_B200134 by the AGAUR (Agencia de Gestió d’ajudes Universitàries i d’investigació) of the Generalitat de Catalunya. With the support of the Secretariat of Universities and Research of the Generalitat de Catalunya and the European Social Fund. Globally, the aim of this whole investigation through a PhD project was to assess the 3D-clinical impact of OS, with regard to direction, magnitude and type of surgical movement, on the upper airway and the clinical improvement and/or cure of the OSA syndrome at long term. Thus, to verify the stability of OS surgical movements when maximizing the PAV and the minimum cross-sectional areas (mCSA), results were evaluated at three time points: pre-, immediate (1-month) and late postoperative (12-months follow-up) throughout the whole investigation. These three time points allowed the authors to be able to state firm conclusions on identifying both the surgical and volumetric gains and possible relapses (short term) and the stability of OS (long-term). Hence, to address the global and specific research purposes, the authors designed and implemented 5 different studies as follows though this rationale: - A systematic review (SR) to study the current the state-of-the art regarding the impact of MMA on the PAV and the AHI in the surgical treatment and definitive cure of OSA (Paper I). Assuming the scarce and lack of homogenic data on this topic: - A retrospective cohort study was performed to demonstrate the relevance of the relationship between the head positioning through the natural head position (NHP) and the Frankfort Horizontal (FH) planes patients with different dentofacial deformities (DFD) (i.e. maxilla/mandibular retrognathia and/or prognathism) and malocclusions (i.e. class I,II or III), thus demonstrating which horizontal plane should be properly executed when planning for OS (Paper II). - As there is no rigorous data regarding the AHI reduction and volumetric, linear and cross-sectional parameters gain after OS, a retrospective longitudinal study of consecutive patients was designed and performed to study the effect of maxillary and mandibular movements (isolated or jointly) on the PAV (nasopharynx, oropharynx, and hypopharynx) and the mCSA on a 3D basis using cone-beam computed tomography (CBCT). In turn, a proposed surgical planning protocol to maximize the UA was designed and validated through this investigation (PaperIII). - On the need of further studies to individualize a required magnitude and direction of surgery-induced movements to patients with DFD, a three case-series study was implemented to validate a protocol and algorithm for the surgical management of DFD in Down syndrome (DS) patients with OSA, when the main concerns are the narrowing of the UA, malocclusion, feeding and speech problems aside from aesthetics (Paper IV). - Finally, the results of a pilot study of an ongoing three arm prospective controlled clinical trial (CCT) (ClinicalTrials.gov ID NCT03796078 registration) are depicted in this PhD project to correlate the magnitude, type, and direction of these skeletal movements with the airway dimension gain or impairment at 12 months follow-up, to propose OS as the definitive and first line treatment armamentarium in selected patients to cure OSA (in terms of AHI and sleep patient-centered parameters) (Paper V).
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47

Guijarro, Martínez Raquel. "Cone-beam computerized tomography (CBCT) evaluation of the upper airway in the context of orthognathic surgery." Doctoral thesis, Universitat Internacional de Catalunya, 2014. http://hdl.handle.net/10803/134767.

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Upper airway analysis has become a key focus of investigation in the fields of Orthognathic Surgery and Orthodontics. This is due to the well-acknowledged relationship between a narrow upper airway and sleep-disordered breathing, and to the association between airway configuration and specific craniofacial phenotypes. As a result of the advancement of the skeletal insertions of the suprahyoid and velopharyngeal muscles, maxillomandibular advancement with counterclockwise rotation has established itself as an effective strategy to increase the pharyngeal airway volume, with subsequent improvement in sleep-disordered breathing symptomatology. These changes can be assessed objectively with cone-beam computerized tomography (CBCT), which has provided a paradigm shift in cranio-maxillofacial imaging due to its capacity to obtain a thorough two- and three-dimensional evaluation of the upper airway at relatively modest costs, with greater accessibility, lower radiation, and shorter scanning times. The most important contributions of this PhD Thesis are the following: 1) Paper one provides the first systematic review of the literature concerning upper airway imaging and analysis with CBCT. Results confirm that CBCT is indeed an accurate and reliable tool for upper airway analysis. Nevertheless, specific problems related to the image acquisition process and to image processing and analysis persist. 2) Paper two is a preliminary CBCT evaluation of the effect of mono- and bimaxillary advancement on the volume of the upper airway. Results showed a systematic volumetric increase for all groups. However, bimaxillary and mandibular advancement achieved a greater percentage increase than maxillary advancement alone. These results suggest the influence of mandibular advancement on the posterior airway space’s dimensions is greater than the effect of the forward movement of the maxilla. 3) Based on the results of the previous two papers, paper three was aimed at providing clinical three-dimensional anatomical limits for the upper airway subregions, translating them into accurate and reliable cephalometric landmarks in CBCT data, and validating the proposed measuring protocol. Our proposed protocol for upper airway subregion analysis proved to be anatomically logical, technically feasible, and statistically reliable.
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48

Lutz, Jean-Christophe. "Development of novel tools based on patient-specific models for guidance and education in orthognathic surgery." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAD017/document.

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Notre pratique courante de la chirurgie orthognathique se heurte aux limites des outils standard de planification et de simulation ainsi qu’à l’absence d’assistance peropératoire. L’objectif de notre travail était de développer de nouveaux outils répondant à cette problématique. Ainsi, dans un premier temps, un algorithme de segmentation semi-automatique a permis une modélisation 3D patient-spécifique rapide et précise. Nous avons ensuite élaboré un logiciel de simulation des parties molles fondé sur un modèle mécanique de type masse-ressort permettant une précision millimétrique. Enfin, nous avons conçu un système de navigation temps-réel fondé sur un guidage électromagnétique mini-invasif doté d’une interface utilisateur intuitive. Son évaluation a montré une réduction de la variabilité inter-opérateurs. En plus de son caractère pédagogique, ce système bénéficiait particulièrement aux débutants. Les chirurgiens ont souligné l’intérêt de ce système, tant pour les dysmorphoses complexes que pour les cas de routine. Ces développements constituent ainsi une suite logicielle susceptible d’améliorer la qualité de prise en charge des patients<br>In our routine practice of orthognathic surgery, we face the limitations of conventional planning and simulation tools, and the lack of convenient intraoperative assistance. If computer science has provided satisfactory solutions for planning, yet simulation and navigation appear improvable. The aim of our research was to provide novel tools to improve these issues. Therefore, we first developed a semi-automated segmentation pipeline allowing accurate and timeefficient patient-specific 3D modeling. We then conceived 1mm-accurate facial soft tissue simulation software based on a mechanical massspring model. Finally, we developed a real-time navigation system based on minimally-invasive electromagnetic tracking, featuring a novel user-friendly interface. Evaluation showed that our software reduced time and accuracy discrepancy between operators. Along with educational purposes, such a system benefited especially trainees. Surgeons emphasized system relevance in the treatment of both, complex and common deformities. Such developments establish a software suite that could provide significant improvement for patient optimal care
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49

AraÃjo, Phelype Maia. "AvaliaÃÃo da via aÃrea posterior de pacientes submetidos à cirurgia de avanÃo maxilo-mandibular." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=9670.

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Universidade Federal do CearÃ<br>A cirurgia ortognÃtica (CO) à uma modalidade de tratamento consagrada na resoluÃÃo dos casos de deformidades dento-faciais, porÃm seus movimentos esquelÃticos provocam diversas alteraÃÃes morfolÃgicas e funcionais nos tecidos moles, oclusÃo dentÃria e via aÃrea. Objetivo: Avaliar as alteraÃÃes volumÃtricas e Ãrea de maior constricÃÃo da via aÃrea superior posterior de pacientes submetidos à cirurgia de avanÃo maxilo-mandibular, correlacionando-as entre si e com a estabilidade Ãssea dos resultados obtidos em trÃs momentos T1 - prÃ-operatÃrio; T2 - pÃs-operatÃrio imediato (15 dias) e T3 - pÃs-operatÃrio tardio. Pacientes e MÃtodos: Trata-se de um estudo retrospectivo no qual foram avaliados atravÃs de tomografias computadorizadas de feixe cÃnico em 3 perÃodos distintos, 22 pacientes, 12 homens e 10 mulheres, submetidos a avanÃo cirÃrgico maxilo-mandibular. A quantificaÃÃo, a estabilidade volumÃtrica e à Ãrea de maior constricÃao foi comparada com a estabilidade Ãssea dos movimentos atravÃs de AnÃlise cefalomÃtrica nos pontos ICS para a maxila e Pog para a mandÃbula, nos trÃs tempos do estudo, correlacionados entre si e entre gÃneros, utilizando software especÃfico. Resultados: O movimento de avanÃo maxilo-mandibular proporcionou um ganho volumÃtrico de vias aÃreas entre T1 e T2 de 8,82cm3 (69,0%) (p<0,01) e uma recidiva de 3,7cm3 (42,0%)(p<0,05) entre T3 e T2 e com um ganho real de 40% entre T1 e T3. Na Ãrea de maior constricÃÃo observou-se um aumento de 1,38cm2 (114%)( (p<0,01) entre T1 e T2 e uma perda de 0,25cm2 (18,40%)(p-0,1844) entre T3 e T2. A mÃdia de avanÃo maxilar foi de 5,64mm (p<0,001) e uma recidiva mÃdia de 0,81mm (14,41%) (p-0,3155), a mÃdia de avanÃo mandibular foi de 14,19mm (p<0,001) e uma recidiva mÃdia de 1,17mm (8,23%) (p-0,2960). Encontrou-se uma correlaÃÃo positiva entre aumento da via aÃrea e aumento da Ãrea constricta (r-pearson â 0,7728) e entre o ganho de volume com sua recidiva (r-pearson â 0,5963). NÃo houve diferenÃa estatÃstica entre os genÃros. ConclusÃes: O avanÃo maxilo-mandibular à um movimento esquelÃtico estÃvel a longo prazo. O volume da via aÃrea apresentou um grande aumento no pÃs-operatÃrio imediato, ocorrendo, no entanto, uma recidiva estatisticamente significante em longo prazo, porÃm o aumento da Ãrea de maior constricÃÃo se manteve estavel em longo prazo.
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50

KARANXHA, LORENA. "ACCURACY OF SPLINT VS SPLINTLESS TECHNIQUE FOR VIRTUALLY PLANNED ORTHOGNATHIC SURGERY: A VOXEL BASED THREE-DIMENSIONAL ANALYSIS." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/703274.

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Virtual planning in orthognathic surgery has nowadays become a clinical reality and has introduced important advantages in terms of accuracy and planning duration when compared to conventional surgical planning. One of the main concerns regarding virtual planning is the method that is used to transfer the virtual surgical plan into the operation theater. With the many transferring methods proposed, the evidence is confusion regarding the accuracy of each of these methods for reliably transferring the virtual plan. Furthermore, the accuracy analysis itself, has been performed with numerous techniques and not all of them are capable of producing reliable results on the accuracy of different transferring methods. The purpose of this study is to compare two transferring methods, the CAD/CAM intermediate splint and the customized surgical guide with fixation plates, by means of a voxel-based landmark free accuracy analysis.
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