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Relevant bibliographies by topics / Orthopedic implants Composite materials. Biomedical materials / Dissertations / Theses

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Dissertations / Theses on the topic 'Orthopedic implants Composite materials. Biomedical materials'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Fang, Liming. "Processing of HA/UHMWPE for orthopaedic applications /." View abstract or full-text, 2003. http://library.ust.hk/cgi/db/thesis.pl?MECH%202003%20FANG.

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Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2003.
Includes bibliographical references (leaves 128-138). Also available in electronic version. Access restricted to campus users.

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2

Bell, Bryan Frederick Jr. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/7962.

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3

Bell, Bryan Frederick. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-06072004-131058/unrestricted/bell%5Fbryan%5Ff%5F200405%5Fms.pdf.

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4

Flanigan, Kyle Yusef. "Synthesis of HAP nano rods and processing of nano-size ceramic reinforced poly (L) lactic acid composites /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/10616.

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5

Wong, Kai-lun, and 黄棨麟. "Strontium-substituted hydroxyapatite reinforced polyetheretherketone biomaterials in orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42182505.

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6

Wong, Kai-lun. "Strontium-substituted hydroxyapatite reinforced polyetheretherketone biomaterials in orthopaedic implants." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182505.

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7

Chang, Hsuan-chen. "Porous bioceramic and biomaterial for bone implants /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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8

Yeung, Che-yan, and 楊芷茵. "Antibacterial properties and biocompatibility of novel peptide incorporated titanium alloy biomaterials for orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hdl.handle.net/10722/197133.

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9

Leung, Kit-ying. "Anti-bacteria plasma-treated metallic surface for orthopaedics use." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41633994.

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10

Bedi, Rajwant Singh. "Anticorrosion and biocompatible Zeolite based coatings for tissue regeneration on metallic bioimplants." Diss., UC access only, 2009. http://proquest.umi.com/pqdweb?index=9&did=1800212961&SrchMode=2&sid=3&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1270057484&clientId=48051.

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Leung, Kit-ying, and 梁潔瑩. "Anti-bacteria plasma-treated metallic surface for orthopaedics use." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41633994.

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12

Lui, So-ching, and 雷素青. "Surface bioactivity enhancement of polyetheretherketone (PEEK) by plasma immersion ion implantation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43572340.

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13

Chong, Yu-wah, and 莊瑜華. "In vitro and in vivo study of plasma immersion ion implantation (PIII)treated polyetheretherketone (PEEK)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B4985883X.

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Polyetheretherketone (PEEK), a polymer with mechanical strength comparable to human bone, is gaining popularity in the orthopedic field because it can potentially relieve the clinical complications, such as stress shielding effect and inevitable implantation failure, which are caused by the mismatch of the mechanical strength between the current metallic implants and the implantation sites. However, it is bio-inert and requires supplementary modification. Plasma immersion ion implantation (PIII) has been well documented that it is a good way to improve the bioactivity of a biomaterial. It is a method that introduces new elements to the biomaterial, generating bio-functional groups on the material surface without altering its mechanical properties. Hence, the aim of this study is to improve the bioactivity of PEEK by modifying its surface chemistry with the use of water (H2O) and ammonia (NH3) plasma immersion ion implantation (PIII) without altering its mechanical properties. After PIII treatment, a series of surface characterization tests that provide information about the surface properties, such as surface energy, roughness, surface chemical composition and crystallinity of PIII-treated PEEK were carried out. Results show that both H2O PIII and NH3 PIII-treated PEEK had significantly higher surface energy and roughness than untreated PEEK. There was also no significant change in the crystallinity of the PIII-treated PEEK, indicating that PIII treatment will not alter the mechanical properties of PEEK. Improvement in wetting properties of PEEK samples suggest the formation of polar functional groups on the PIII-treated PEEK materials, while the increased in surface roughness may be due to the energetic bombardments of plasma ions on the material surface. The in vitro bioactivity of plasma-treated PEEK was investigated and confirmed with hMSC-TERT. Initial cell attachment, cell spreading area, cell proliferation and differentiation were studied. Cell adhesion and cell spreading were enhanced on PIII-treated PEEK, and higher cell viability was observed on PIII-treated PEEK. Moreover, cell proliferation was promoted on early time point and cell differentiation was also enhanced particularly on day 7 by measuring the alkaline phosphatase activity. Therefore, H2O-PIII and NH3-PIII treatments were able to promote the bioactivity of PEEK samples.
published_or_final_version
Orthopaedics and Traumatology
Master
Master of Philosophy

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14

Lui, So-ching. "Surface bioactivity enhancement of polyetheretherketone (PEEK) by plasma immersion ion implantation." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43572340.

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15

Kuthe, Sudhanshu. "Multimaterial 3D Printing of a mechanically representative aortic model for the testing of novel biomedical implants." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-260281.

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Aortic stenosis is a serious cardiovascular disease that requires urgent attention and surgical intervention. If not treated, aortic stenosis can result in heart attack or cardiac arrest. Transcatheter Aortic Valve Replacement is a surgical technique that is used to treat aortic stenosis. Like all heart surgery, the procedure is difficult to perform and may lead to life-threatening complications. It is therefore important for a surgeon to be able to plan and rehearse the surgery before the operation to minimise risk to the patient. A detailed study was carried out to develop a 3D-printed, improved surgical tool for patient-specific planning and rehearsal of a Transcatheter Aortic Valve Replacement procedure. With this new tool, a cardiologist will be able better to understand a specific patient’s heart geometry and practice the procedure in advance. Computer tomography images were processed using image segmentation software to identify the anatomy of a specific patient’s heart and the surrounding blood vessels. Using materials design concepts, a polymer composite was developed that is able to mimic the mechanical properties of aortic tissue. State-of-art multi-material 3D printing technology was then used to produce a replica aorta with a geometry that matched that of the patient. An artificial aortic valve, identical to the type used in the Transcatheter Aortic valve replacement procedure, was then fitted to the replica aorta and was shown, using a standard test, to be a good fit with no obvious leaks.
Aortastenos är en hjärtsjukdom som får mycket uppmärksamhet och kräver kirurgi på grund av dess katastrofala komplikationer. Den allvarligaste komplikationen av aortastenos är hjärtinfarkt och resulterande hjärtstopp. Transcatheter Aortic Valve Replacement är en kardiovaskulär intervention som erbjuds för patienter med aortastenos. Denna typ av hjärtkirurgi är komplex och kan orsaka livshotande situationer för patienten om något går snett under operationen. Det är därför viktigt för kirurgen att kunna planera ingreppet innan han eller hon utför själva operationen för att minimera fara för patienten. Denna detaljerade studie ämnar utveckla och förbättra det kirurgiska verktyget för preoperativ planering av Transcatheter Aortic Valve Replacement genom 3D- tryckning. Forskningsarbetet kommer att ge kardiologer ett nytt sätt att förstå patientens hjärta i detalj och ett ökat förtroende för att träna på ingreppet på förhand. Datortomografibilder behandlades med hjälp av en bildsegmentationsprogramvara för att kunna skapa en anatomiskt korrekt kopia av patientens hjärta och tillhörande kärl. Genom att applicera material-vetenskapslära kan ett nytt kompositmaterial utvecklas med exakt samma mekaniska egenskaper som naturlig aortavävnad. Den mest moderna 3D-trycktekniken användes sedan för att producera en patientspecifik aorta. En artificiell aortaklaff placerades i den nyproducerade aortamodellen och tester visade en perfekt matchning utan läckage.

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16

Reyes, Catherine Diane. "Collagen- and Fibronectin-Mimetic Integrin-Specific Surfaces That Promote Osseointegration." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/11599.

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Cell adhesion to the extracellular matrix through cell-surface integrin receptors is essential to development, wound healing, and tissue remodeling and therefore represents a central theme in the design of bioactive surfaces that successfully interface with the body. This is especially significant in the areas of integrative implant coatings since adhesion triggers signals that regulate cell cycle progression and differentiation in multiple cellular systems. The interactions of osteoblasts with their surrounding extracellular matrix are essential for skeletal development and homeostasis and the maintenance of the mature osteoblastic phenotype. Our objective was to engineer integrin-specific bioactive surfaces that support osteoblastic differentiation and promote osseointegration by mimicking these interactions. We target two specific integrins essential to osteoblast differentiation the type I collagen receptor alpha2beta1 and the fibronectin receptor alpha5beta1. The central hypothesis of this project was that the controlled presentation of type I collagen and fibronectin binding domains onto well-defined substrates would result in integrin-specific bioadhesive surfaces that support osteoblastic differentiation, matrix mineralization, and osseointegration. We have demonstrated that these biomimetic peptides enhance bone formation and mechanical osseointegration on titanium implants in a rat tibia cortical bone model. We have also shown that the presentation of multiple integrin-binding ligands synergize to enhance intracellular signaling and proliferation. Finally, we demonstrate the advantage of the short biomimetic peptides over the native ECM proteins. This research is significant because it addresses current orthopaedic implant limitations by specifically targeting cellular responses that are critical to osteoblastic differentiation and bone formation. This biomolecular approach provides a versatile and robust strategy for developing bioactive surfaces that enhance bone repair and osseointegration of orthopaedic implants.

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