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1

Konovchuk, Viktor M., Sergiy V. Kushnir, Andriy V. Andrushchak, Iryna I. Iliuk, and Petro V. Moroz. "THE CONDITION OF VOLUMETRIC AND OSMOREGULATORY FUNCTION OF THE KIDNEYS IN TOXICEMIA OF PURULENT-SEPTIC GENESIS IN PATIENTS WITH DIABETES MELLITUS." Wiadomości Lekarskie 73, no. 4 (2020): 733–36. http://dx.doi.org/10.36740/wlek202004120.

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The aim of the study is to investigate the state of volumetric and osmoregulatory function of the kidneys in diabetes complicated by the syndrome of the endogenous intoxication of purulent-septic genesis. Materials and methods: The study group was consisted of patients with insulin-dependent diabetes mellitus with complicated syndrome of the endogenous intoxication of purulent-septic genesis (CSDI). Results: The starting indices of volumetric and osmoregulatory function of the kidneys in patients with INCs complicated by the endogenous intoxication of purulent-septic genesis (CEI GHG) syndrome
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2

Konovchuk, V.M., S.V. Kushnir, A.V. Andrushchak, and M.O. Andrushchak. "The influence of xylate on the volumo- and osmoregulatory function of the kidneys in diabetes complicated by the syndrome of endogenous intoxication of purulent-septic origin." Medicni perspektivi 25, no. 1 (2020): 104–9. https://doi.org/10.26641/2307-0404.2020.1.200408.

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The combination of insulin-independent diabetes mellitus with endogenous purulent-septic genesis syndrome is a fairly common nosology. The search for ways to optimize the results of its treatment, after screening observations, led to the expediency to consider the pharmacodynamic aspects of the action of polyhydric alcohols through the prism of homeostatic support functions. Detailing this direction was focused on the consideration of the action of xylate mediated through the volumetric and osmoregulatory function of the kidneys. The effect of xylate on the volumo-and osmoregulatory function o
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3

Kuznetsova, E. S., E. N. Kuznetsova, V. V. Shuhtin та A. I. Gozhenko. "Особенности осморегулирующей функции почек у больных с сахарным диабетом 1 типа = Features of the renal osmoregulatory function in patients with type 1 diabetes". Journal of Education, Health and Sport 5, № 8 (2015): 64–72. https://doi.org/10.5281/zenodo.23452.

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<strong>Kuznetsova E</strong><strong>.</strong><strong> S</strong><strong>., </strong><strong>Kuznetsova E</strong><strong>.</strong><strong> N</strong><strong>., </strong><strong>Shuhtin V</strong><strong>.</strong><strong> V</strong><strong>., </strong><strong>Gozhenko A</strong><strong>.</strong><strong> I</strong><strong>.</strong> <strong>О</strong><strong>собенности осморегулирующей функции почек у больных с сахарным диабетом 1 типа = </strong><strong>F</strong><strong>eatures</strong> <strong>of</strong> <strong>the</strong> <strong>renal</strong> <strong>osmoregulatory</strong> <strong
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4

Smirnova, O. V., P. A. Abramicheva, and N. S. Pavlova. "Osmoregulation and reproduction: evolutionary trends in prolactin functions from fish to mammals." Vestnik Moskovskogo universiteta. Seria 16. Biologia, no. 2S, 2024 (October 8, 2024): 46–54. http://dx.doi.org/10.55959/msu0137-0952-16-79-2s-10.

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The study of prolactin function evolution provides key insights into the diverse effects of this hormone in mammals, both in health and disease, which is relevant from both theoretical and practical perspectives. This article reviews both original and literature data concerning the role of prolactin and its receptors in regulating the sexual dimorphism of freshwater adaptation in the three-spined stickleback Gasterosteus aculeatus L. It is demonstrated that mRNA expression of prolactin gene 1 (one of two prolactin paralogs) and its receptor PRLRA increases in the brains of female sticklebacks
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5

Surendran, Surya, and M. Ampili. "Morphological Changes and Ionic Regulations in Gills of Euryhaline Fish during Osmoregulation: A Review." UTTAR PRADESH JOURNAL OF ZOOLOGY 44, no. 18 (2023): 11–17. http://dx.doi.org/10.56557/upjoz/2023/v44i183599.

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Euryhaline fish can thrive in both freshwater habitat and saltwater conditions. The migration from one salinity range to another involves the use of various organs like gills, kidneys and intestine which are all osmoregulatory in function. Among them, gills are considered to be the most important osmoregulatory organ with multiple functions and various ion transporters which helps the fish to survive the adverse environmental conditions. The gills have various cells involved in osmoregulation and mainly the MR (Mitochondria Rich) cells which have many transporters for intake and excretion of i
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6

Nishimura, Hiroko, and Yimu Yang. "Aquaporins in avian kidneys: function and perspectives." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 305, no. 11 (2013): R1201—R1214. http://dx.doi.org/10.1152/ajpregu.00177.2013.

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For terrestrial vertebrates, water economy is a prerequisite for survival, and the kidney is their major osmoregulatory organ. Birds are the only vertebrates other than mammals that can concentrate urine in adaptation to terrestrial environments. Aquaporin (AQP) and glyceroporin (GLP) are phylogenetically old molecules and have been found in plants, microbial organisms, invertebrates, and vertebrates. Currently, 13 AQPs/aquaGLPs and isoforms are known to be present in mammals. AQPs 1, 2, 3, 4, 6, 7, 8, and 11 are expressed in the kidney; of these, AQPs 1, 2, 3, 4, and 7 are shown to be involve
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7

Franco-Acevedo, Adriana, Raquel Echavarria, and Zesergio Melo. "Sex Differences in Renal Function: Participation of Gonadal Hormones and Prolactin." Endocrines 2, no. 3 (2021): 185–202. http://dx.doi.org/10.3390/endocrines2030019.

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Kidney pathophysiology is influenced by gender. Evidence suggests that kidney damage is more severe in males than in females and that sexual hormones contribute to this. Elevated prolactin concentration is common in renal impairment patients and is associated with an unfavorable prognosis. However, PRL is involved in the osmoregulatory process and promotes endothelial proliferation, dilatation, and permeability in blood vessels. Several proteinases cleavage its structure, forming vasoinhibins. These fragments have antagonistic PRL effects on endothelium and might be associated with renal endot
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8

Kuznetsova, E. S., A. S. Kuznetsova, V. V. Shuhtin та A. I. Gozhenko. "РARTICULAR QUALITIES OF THE RENAL OSMOREGULATORY FUNCTION IN PATIENTS WITH TYPE 2 DIABETES". Ukrainian Journal of Nephrology and Dialysis, № 4(48) (23 листопада 2015): 21–26. http://dx.doi.org/10.31450/ukrjnd.4(48).2015.03.

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The aim of the study was to examine the osmoregulatory state of renal function in patients with type 2 diabetes in a water - salt load with 0,5% NaCl in the amount of 0.5% of body weight.&#x0D; Materials and methods. The study involved 56patients with insulin - dependent diabetic nephropathy,24 men (42.9%) and 32 women (57.1%), aged from 38 to 81 years. The osmolality was measured by freezing point depression on osmomat 030 - D (USA). Glomerular filtration rate (GFR) was calculated by the formula GFR - EPI with subsequent determination of renal functional reserve.&#x0D; Results. It demonstrate
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9

Natochin, Yu V., A. A. Kuznetsova, А. V. Nistarova, and A. S. Marina. "DEPENDENCE OF RENAL FUNCTION ON THE STATE OF WATER-SALT BALANCE IN CHILDREN WITH CYSTIC FIBROSIS." Pediatria. Journal named after G.N. Speransky 100, no. 4 (2021): 26–32. http://dx.doi.org/10.24110/0031-403x-2021-100-4-26-32.

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The aim is to study the osmoregulatory renal function as a key mechanism for cell volume regulation in patients with cystic fibrosis (CF). Materials and methods of research: 59 children were examined (CF, n=24; pneumonia, n=19; healthy children, n=15). Osmoregulatory function was assessed after fluid restriction during the night and water load of 10 ml per kg of body weight. Results: CF patients showed a positive correlation between the renal clearances of solute free water and sodium free water in night urine specimens. After water loading, similar renal reaction was found in all groups of ex
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10

Pavlova, N. S., T. V. Neretina, and O. V. Smirnova. "Expression of Prolactin Axis Genes in the Brain, Gills and Kidneys of the Three-Spined Stickleback <i>G. Aculeatus L.</i>: Dependency on Freshwater Adaptation and Sex." Žurnal èvolûcionnoj biohimii i fiziologii 60, no. 5 (2024): 562–72. https://doi.org/10.31857/s0044452924050101.

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The dependence of prolactin gene (Prl1) expression on sex in the brain and its receptors (PrlRa and PrlRb) in the brain, kidneys, gills, and intestine of the three-spined stickleback (Gasterosteus aculeatus L.) was studied in the context of freshwater adaptation. Males and females of the marine morph were adapted to freshwater for 72 hours, and the expression levels of Prl1 in the brain and PrlRa and PrlRb in the examined organs were assessed using RT-PCR. In seawater, no sex differences in Prl1 gene expression in the brain were observed; however, after freshwater adaptation, significant sex d
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11

Dzgoev, S. G. "Modeling of rheumatoid arthritis is accompanied by a change in the cortico-papillary ratio of hyaluronidase activity of the kidneys." Nephrology (Saint-Petersburg) 27, no. 3 (2023): 86–91. http://dx.doi.org/10.36485/1561-6274-2023-27-3-86-91.

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Background. Rheumatoid arthritis is a disease that is accompanied by impaired kidney function in most patients, which attracts the attention of researchers to this problem. Both in the joints and in the kidneys, hyaluronic acid plays an important role, the degree of polymerization of which depends on the functioning of these organs. The degradation of hyaluronic acid by hyaluronidases may be a factor involved in the development of the inflammatory process in rheumatoid arthritis as well as in the realization of osmoregulatory functions of the body. In this regard, the purpose of this work was
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12

Murkamilov, I. T., K. A. Aitbaev, V. V. Fomin, et al. "Functional state of the kidneys in patients with various types of cerebrovascular diseases." S.S. Korsakov Journal of Neurology and Psychiatry 125, no. 1 (2025): 105. https://doi.org/10.17116/jnevro2025125011105.

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Objective. To study the functional state of the kidneys in men and women with various types of cerebrovascular diseases (CVD). Material and methods. The study included 378 patients with CVD: transient ischemic attack (TIA), stroke (ischemic and hemorrhagic), and chronic brain ischemia. The average age of men and women was 61.4±13.0 and 63.8±11.8 years, respectively. The excretory function of the kidneys was assessed in all participants. Results. TIA was recorded in 20.9% of men and 13.4% of women. Stroke was verified in 35.7% of patients (56.4% men and 34.3% women, p&lt;0.05). Recurrent ischem
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13

Krayacich, J., R. L. Kline, and P. F. Mercer. "Supersensitivity to NE alters renal function of chronically denervated rat kidneys." American Journal of Physiology-Renal Physiology 252, no. 5 (1987): F856—F864. http://dx.doi.org/10.1152/ajprenal.1987.252.5.f856.

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The effect of norepinephrine (NE) infusion (10, 100, and 330 ng/min, iv) on renal blood flow (RBF), glomerular filtration rate (GFR), urine flow, and sodium excretion was studied during ganglionic blockade in Inactin-anesthetized Wistar rats with one kidney innervated and the contralateral kidney denervated 7-10 days before the experiment. During the NE infusions, steady-state mean arterial pressure was 73 +/- 3, 91 +/- 5, and 117 +/- 2 mmHg, whereas plasma NE concentration averaged 3.9 +/- 1.2, 26.4 +/- 3.2, and 78.1 +/- 4.8 pmol/ml, respectively. At the lowest dose, RBF and GFR were decrease
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14

CHARIEV, M. "H18 Filtrational kidneys function reserve state in women with hypertonic disease." American Journal of Hypertension 10, no. 4 (1997): 187A. http://dx.doi.org/10.1016/s0895-7061(97)89337-5.

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15

Khatamova, Matluba Tilavovna. "MODERN ISSUES OF PREVENTION OF COVID-19 AND KIDNEY STATE IN WOMEN OF REPRODUCTIVE AGE FOR UNCOMPLICATED PREGNANCY." Thematic Journal of Applied Sciences 3, no. 4 (2023): 25–27. https://doi.org/10.5281/zenodo.8124246.

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Abstract: With an uncomplicated pregnancy in a woman&#39;s body, a number of adaptive and adaptive processes develop (hypervolemia, fluid accumulation, changes in the content of electrolytes and non-electrolytes), in which the kidneys are directly involved. On the other hand, the appearance of uteroplacental blood circulation, an increase in regional hemodynamics during pregnancy cannot but affect the functional state of the kidneys of a pregnant woman. During physiological pregnancy, specific changes in kidney function occur, aimed at ensuring the normal process of gestation. However, ultraso
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16

Sinyakova, L. A., E. V. Bernikov, and O. B. Loran. "Kidneys functional state in patients suffered purulent pyelonephritis." Herald Urology 6, no. 4 (2019): 49–59. http://dx.doi.org/10.21886/2308-6424-2018-6-4-49-59.

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Introduction. Purulent pyelonephritis is a complicated urinary tract infection with one of the most severe currents. It represents a serious clinical problem associated with the complexity of the choice of diagnosis and the optimal active treatment strategy, as well as the need for subsequent rehabilitation of this category of patients.Purpose of the study. Studying of the immediate and remote results of the kidneys` functional state in patients who have undergone purulent pyelonephritis using a differentiated approach to treatment tactics.Materials and methods. The study included 84 patients
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17

Moratal, Claudine, Audrey Laurain, Mourad Naïmi, et al. "Regulation of Monocytes/Macrophages by the Renin–Angiotensin System in Diabetic Nephropathy: State of the Art and Results of a Pilot Study." International Journal of Molecular Sciences 22, no. 11 (2021): 6009. http://dx.doi.org/10.3390/ijms22116009.

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Diabetic nephropathy (DN) is characterized by albuminuria, loss of renal function, renal fibrosis and infiltration of macrophages originating from peripheral monocytes inside kidneys. DN is also associated with intrarenal overactivation of the renin–angiotensin system (RAS), an enzymatic cascade which is expressed and controlled at the cell and/or tissue levels. All members of the RAS are present in the kidneys and most of them are also expressed in monocytes/macrophages. This review focuses on the control of monocyte recruitment and the modulation of macrophage polarization by the RAS in the
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18

Ugleva, T. N,, and L. A. Alexeenko. "KIDNEY FUNCTION IN NEWBORN CHILDREN." EurasianUnionScientists 5, no. 7(76) (2020): 54–59. http://dx.doi.org/10.31618/10.31618/esu.2413-9335.2020.5.76.932.

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Objective. The article discusses the problem of assessing renal function of the kidneys in premature babies born as a result of prematurely premature births with extremely low birth weight. Materials and methods. The functional state of the kidneys was evaluated in 148 children with ELBW and VLBW in the period from 1 to 90 days of postnatal age. The urine output rate, serum creatinine level, GFR calculation according to the Schwartz formula. Results. The results of the study showed that premature babies with ELBW are characterized by elevated serum creatinine levels and a low glomerular filtra
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19

Konovchuk, V. M., S. V. Kushnir, A. V. Andrushchak, and M. O. Andrushchak. "The influence of xylate on the volumo- and osmoregulatory function of the kidneys in diabetes complicated by the syndrome of endogenous intoxication of purulent-septic origin." Medicni perspektivi (Medical perspectives) 25, no. 1 (2020): 104–9. http://dx.doi.org/10.26641/2307-0404.2020.1.200408.

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20

Jullien, Martial, Guy Thériault, Michel G. Bergeron, and Denis Beauchamp. "Effect ofEnterococcus faecalisPyelonephritis on the Intracortical Accumulation Kinetics of Gentamicin in Rats." Canadian Journal of Infectious Diseases 1, no. 4 (1990): 117–20. http://dx.doi.org/10.1155/1990/285781.

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The role of serum levels on the intracortical accumulation kinetics of gentamicin was evaluated in normal andEnterococcus faecalis-infected kidneys using a short term infusion model in conscious rats. Female Sprague-Dawley rats were infused over a period of 6 h with gentamicin achieving individual steady-state serum levels ranging from 0.5 to 20 μg/mL. Pyelonephritis was induced by a direct inoculation of the left kidney with a suspension ofE faecalis.This model resulted in severe infection of the left kidney and mild infection of the right kidney. Gentamicin cortical concentrations were analy
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21

Paketov, S. A., S. A. Oskolkov, V. A. Zhmurov, D. V. Zhmurov, and R. D. Novikov. "Renal function characteristic in patients with chronic kidney disease, chronic pyelonephritis and arterial hypertension." Medical Science And Education Of Ural 21, no. 4 (2020): 16–18. http://dx.doi.org/10.36361/1814-8999-2020-21-4-16-18.

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Aim. To analyze nephroscintigraphy kidney functional state in patients with chronic kidney disease (CKD) on the background of chronic pyelonephritis (CRF) in combination with arterial hypertension (AH). Materials and methods. 81 patients with chronic kidney disease on the background of arterial hypertension and chronic pyelonephritis in the phase of incomplete clinical and laboratory remission were included in the research. Age varied from 25 to 60 years old (average age was 46 ± 9.0 years). The study was performed on the basis of Tyumen railway hospital and Tyumen state medical University mul
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22

Mikhaylova, L. V., E. M. Romanova, and U. A. Dobrynina. "CHRONIC KIDNEY DISEASE OF CARDIAC PATIENTS." Medical academic journal 18, no. 2 (2018): 96–100. http://dx.doi.org/10.17816/maj18296-100.

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The aim of the study was to evaluate the functional state of the kidneys in patients with cardiological profile. Material and methods: a retrospective analysis of 208 case histories of patients discharged from the 1st and 2nd cardiological departments of the State Budgetary Healthcare Institution Regional Kaliningrad Clinical Hospital was conducted, 110 of them (53%) were men and 98 (47%) were women. The average age of the patients was 63 (56.0, 71.0) years. To evaluate the kidney function, a calculation method for determining GFR using the formula CKD-EPI in ml/min/1.73 m2 was used. Results:
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23

Pauliana and I. Wayan Sunaka. "Acute kidney injury in patient with acute gastroenteritis and history of consuming energy drink." International Journal of Advances in Medicine 11, no. 5 (2024): 524–27. http://dx.doi.org/10.18203/2349-3933.ijam20242319.

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An abrupt decline in kidney function is a characteristic of acute kidney injury (AKI), a disorder that affects the structure and function of the kidneys. Hypovolemia from gastroenteritis is known as one of the causes from prerenal AKI. Energy drinks, which are consumed a lot by workers and young people are also known can decrease kidney function and liver function even without having any pre-existing diseases. There were two reported cases of consumption energy drink that worsening kidney and liver function in gastroenteritis patient with mild-moderate dehydration state.
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24

Belkorey, O. S., E. N. D’yakova, V. N. Oslopov, and N. R. Khasanov. "Features of drug therapy for patients with myocardial infarction and different glomerular filtration rates." Kazan medical journal 97, no. 6 (2016): 887–92. http://dx.doi.org/10.17750/kmj2016-887.

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Aim. To study the features of treatment of patients with myocardial infarction and different functional state of kidneys at outpatient and inpatient stages of treatment.Methods.A retrospective study included 179 patients admitted to the hospitals of Moscow North-Eastern Administrative District with verified diagnosis of myocardial infarction. Depending on glomerular filtration rate all patients were divided into two groups: patients with acute myocardial infarction and with GFR of ≥60 ml/min/1.73 m2, and those with GFRResults. Prevalence of arterial hypertension among patients with decreased f
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Alekseienko, Roman, Volodymyr Markovskiy, Liubov Rysovana та ін. "Study of the relationship between the level of pro-inflammatory cytokines and β2-microglobulin with indicators of changes in the functional status of the kidneys in diabetic nepropathy to determine the degrees of chronic renal failure". Wiadomości Lekarskie, № 2 (28 лютого 2025): 248–56. https://doi.org/10.36740/wlek/197132.

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AimThe purpose of this study is to analyze the correlations of pro-inflammatory cytokines and β2-microglobulin with indicators of changes in the functional state of kidneys in patients with diabetic nephropathy, to determine different degrees of chronic renal failure.Material and methods80 patients with type 1 and type 2 diabetes, complicated by diabetic nephropathy, at different levels of the functional state of the kidneys were examined.ResultsIt has been shown that the level of tumor necrosis factor α (TNFα) in the blood of patients with diabetic nephropathy (DN) is increased already with s
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26

Kurmangaliev, O. M., Boris V. Zasorin, Zh Zh Gumarova, and E. E. Sartaev. "State of kidneys of the population of the industrial city." Hygiene and sanitation 95, no. 8 (2019): 734–37. http://dx.doi.org/10.18821/0016-9900-2016-95-8-734-737.

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The assessment of renal functions of the adult population of Atyrau (West Kazakhstan) exposed to Atyrau oil refinery and other industrial objects (enterprises in the city), as well as employees of this refinery has been performed by virtue of the identification ofpathological changes in the urine with the use ofphotometric screening, determination of serum levels of creatinine, urea, uric acid and the calculation of glomerular filtration rate. There were obtained evident data testifying to the development of statistically significant exertion of renal function in residents of this city as comp
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27

Borschovetska, Vira, and Valeriia Mamiienko. "Biochemical indicators of renal functional state under the conditions of bisphenol A administration and low-level laser irradiation." Biolohichni systemy 12, no. 2 (2020): 180–86. http://dx.doi.org/10.31861/biosystems2020.02.180.

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Nowadays, due to the mass production of plastic products, the question of the negative impact of bisphenol A on the functioning of organs and systems is acute. However, the question of the effect of this xenobiotic on the functional state of the kidneys remains open. Currently, laser irradiation of various powers is intensively used to correct pathologies. However, its biochemical feathers of the impact on biological objects require detailed research. The work is aimed at the study of nephrotoxic effects of bisphenol A under the conditions of irradiation of animals with a diode laser. ВРА was
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28

Dadashyan, A. M., and G. N. Sorokina. "Renal function in chronic lung diseases of non-tuberculous etiology." Kazan medical journal 43, no. 3 (2021): 70. http://dx.doi.org/10.17816/kazmj83909.

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We investigated the functional state of the kidneys in 20 patients with bronchiectasis, 13 with bronchial asthma and 7 with lung abscesses. Zimnitsky's test was normal in 12 patients, isogppostenuria and nocturia were found in 9, and nocturia in 19. Fonno's test was carried out in 31 patients. In 18 it turned out to be normal, in 13 patients a violation of the excretory function was revealed. Albuminuria was observed in 8, microhematuria - in 4, urobilinuria - in 17. The level of residual nitrogen was normal in 39 and increased in one patient.
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29

Tucci Jr, Silvio, Carlos Augusto Fernandes Molina, Adauto José Cologna, et al. "Compensatory renal growth and mitochondrial function: the influence of warm ischemia and reperfusion." Acta Cirurgica Brasileira 23, suppl 1 (2008): 31–35. http://dx.doi.org/10.1590/s0102-86502008000700006.

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PURPOSE: To evaluate the influence of ischemia/reperfusion injury on renal compensatory growth (CGR) and mitochondrial function. METHODS: Forty five Wistar rats were divided in 3 groups: Control Group (GC) - 21 rats were submitted to a sham laparotomy and sacrificed at 1st (6 rats) and 7th (15 rats) postoperative days to evaluate the dry weight of both kidneys and their growth during 1 week (6 rats) and to quantify mitochondrial respiration (9 rats); Group 1 (G1) - 12 rats underwent right nephrectomy and were sacrificed 7 days later for analysis of renal mitochondrial function (6 rats) and dry
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30

Engeham, Sarah, Kennedy Mdaki, Kirsty Jewell, Ruth Austin, Alexander N. Lehner, and Simon C. Langley-Evans. "Mitochondrial Respiration Is Decreased in Rat Kidney Following Fetal Exposure to a Maternal Low-Protein Diet." Journal of Nutrition and Metabolism 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/989037.

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Maternal protein restriction in rat pregnancy is associated with impaired renal development and age-related loss of renal function in the resulting offspring. Pregnant rats were fed either control or low-protein (LP) diets, and kidneys from their male offspring were collected at 4, 13, or 16 weeks of age. Mitochondrial state 3 and state 4 respiratory rates were decreased by a third in the LP exposed adults. The reduction in mitochondrial function was not explained by complex IV deficiency or altered expression of the complex I subunits that are typically associated with mitochondrial dysfuncti
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31

Murkamilov, I. T., K. A. Aitbaev, V. V. Fomin, et al. "Renal function and cardiovascular risk in overweight patients." Nephrology (Saint-Petersburg) 28, no. 1 (2024): 50–62. http://dx.doi.org/10.36485/1561-6274-2024-28-1-50-62.

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Background. Currently, in most countries of the world, there is a tendency for an annual increase in the proportion of overweight people (OW). Studies performed in various age groups and devoted to the relationship of OW with the functional state of the kidneys show contradictory results.The aim: to study the functional state of the kidneys and the prevalence of risk factors for cardiovascular complications in OW, taking into account gender differences.Patients and Methods. A cross–sectional single-center study was conducted with the participation of 154 patients (73 men and 81 women) with bod
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32

Kuchmenko, O., L. Mkhytaryan, I. Ievstratova, O. Matova, and V. Vasylchenko. "The possibility of using citrulline as a new biochemical marker to evaluate the state of kidney under cardiovascular pathologies." Ukrainian Journal of Nephrology and Dialysis, no. 4(60) (December 26, 2018): 35–39. http://dx.doi.org/10.31450/ukrjnd.4(60).2018.05.

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The aim of our work was to study the level of citrulline in serum as a biochemical marker of the functional state of the kidneys in patients with cardiovascular pathologies.&#x0D; Methods. The study included 134 patients aged 41-68 years, of which 40 patients with stage II arterial hypertension (AG-II) and 62 patients with chronic heart failure (AG in combination with chronic ischemic heart disease) in the IIa and IIb stages. The control group included 32 practically healthy persons of the corresponding age. Along with standard diagnostic methods, the content of citrulline in serum was determi
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33

Nisarga P, Ms, and Ms Kanchana V. "Data Mining Techniques to Predict Chronic Kidney Disease and its Stages." International Journal of Engineering & Technology 7, no. 3.10 (2018): 27. http://dx.doi.org/10.14419/ijet.v7i3.10.15623.

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Chronic Kidney Disease incorporates the state where the kidneys fail to function and reduce the potential to keep a person suffering from the disease healthy. When the condition of the kidneys gets worse, the wastes in the blood are formed in high level. Data mining has been a present pattern for accomplishing analytic outcomes. Colossal measure of un-mined data is gathered by the human services industry so as to find concealed data for powerful analysis and basic leadership. Data mining is the way towards extricating concealed data from gigantic datasets. The goal of our paper is to anticipat
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Warford-Woolgar, Lori, Claudia Yu-Chen Peng, Jamie Shuhyta, et al. "Selectivity of cyclooxygenase isoform activity and prostanoid production in normal and diseased Han:SPRD-cy rat kidneys." American Journal of Physiology-Renal Physiology 290, no. 4 (2006): F897—F904. http://dx.doi.org/10.1152/ajprenal.00332.2005.

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Renal prostanoids are important regulators of normal renal function and maintenance of renal homeostasis. In diseased kidneys, renal cylooxygenase (COX) expression and prostanoid formation are altered. With the use of the Han:Sprague-Dawley- cy rat, the aim of this study was to determine the relative contribution of renal COX isoforms (protein, gene expression, and activity) on renal prostanoid production [thromboxane B2 (TXB2, stable metabolite of TXA2), prostaglandin E2 (PGE2), and 6-keto-prostaglandin F1α (6-keto-PGF1α, stable metabolite of PGI2)] in normal and diseased kidneys. In diseased
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35

Tsintsadze, Bella D. "Cystatin C and lipocalin — endogenous markers of glomerular filtration in children born prematurely." Russian Pediatric Journal 25, no. 3 (2022): 206–11. http://dx.doi.org/10.46563/1560-9561-2022-25-3-206-211.

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The need to search for new markers of the functional state of the kidneys is increasing due to the gain in the number of extremely premature infants. The review analyzes publications on the possibilities of assessing kidney function using cystatin C and lipocalin in children born prematurely. The constant rate of cystatin C production in all tissues, its elimination through the renal glomerular filter, the absence of secretion in the proximal tubules, as well as independence from many factors, including gender, age, diet, inflammation are ideal conditions for its use as an endogenous biochemic
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36

Ospanova, T. S., Zh D. Semydotska, I. O. Cherniakova, O. M. Pionova, N. S. Tryfonova, and O. V. Avdieieva. "COPD and Kidneys: Two Sides of the One Problem." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5, no. 5 (2020): 170–79. http://dx.doi.org/10.26693/jmbs05.05.170.

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The problems of diagnosis, treatment, prevention of chronic obstructive pulmonary disease remain relevant due to the increase in morbidity, disability and mortality of patients. Recently, the level of renal dysfunction in the progression of chronic obstructive pulmonary disease has increased. The purpose of research was to study the indicators of renal dysfunction in chronic obstructive pulmonary disease, depending on the severity and frequency of chronic obstructive pulmonary disease exacerbations, comorbidity, respiratory function, morphological and functional state of the myocardium to opti
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37

Kirpatovskii, V. I., A. V. Kazachenko, E. Yu Plotnikov, T. A. Kon’kova, V. V. Drozhzheva, and D. B. Zorov. "Effects of ischemic and hypoxic preconditioning on the state of mitochondria and function of ischemic kidneys." Bulletin of Experimental Biology and Medicine 143, no. 1 (2007): 105–9. http://dx.doi.org/10.1007/s10517-007-0028-8.

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38

Proskura, A. V., Yu G. Alyaev, V. V. Borisov, et al. "Assessment of the kidney functional state prior and after partial nephrectomy for a unilateral tumor using mathematical processing of computed tomography data with contrast enhancement." Andrology and Genital Surgery 24, no. 3 (2023): 66–74. http://dx.doi.org/10.17650/2070-9781-2023-24-3-66-74.

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Background. According to the contemporary data available contrast-enhanced computed tomography can be used to assess total and split kidney function. The Urology Clinic of the I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University) utilizes mathematical processing of computed tomography data for the assessment of split kidney function.Aim. To evaluate the effect of main renal artery clamping (warm ischemia time) during partial nephrectomy for a unilateral tumor on the kidney function.Materials and methods. 33 patients of both sexes who underwent
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39

Matova, O. O., K. I. Serbeniuk, L. V. Bezrodna, V. B. Bezrodnyi, and V. V. Radchenko. "DYNAMICS OF FUNCTIONAL STATE OF KIDNEYS IN PATIENTS WITH RESISTANT HYPERTENSION AND CHRONIC KIDNEY DISEASE ACCORDING TO LONG-TERM FOLLOW-UP." International Medical Journal, no. 4(104) (February 28, 2020): 5–11. http://dx.doi.org/10.37436/2308-5274-2020-4-1.

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Resistant hypertension and chronic kidney disease are closely related from a pathogenetic and clinical point of view. To study the dynamics of functional state of kidneys and as well as to identify the predictors of its improvement, 117 patients with resistant hypertension were examined. Dynamic follow−up of patients included monitoring of antihypertensive therapy, blood pressure, biochemical and humoral parameters during 3, 6 and 36 months of treatment. The findings have shown that a significant long−term improvement in blood pressure control in the patients with chronic kidney disease improv
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40

Pak, Yu G., and D. M. Yagudaev. "The influence of endovideoscopic surgeries for nephrolithiasis on the kidneys’ functions." Experimental and Сlinical Urology 15, no. 1 (2022): 85–89. http://dx.doi.org/10.29188/2222-8543-2022-15-1-85-89.

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Introduction. In recent years, there has been a persistent trend towards an increase in the incidence of urolithiasis. The treatment of large and complex kidney stones greatest difficulty is one of the challenges. Such stones, as well as surgical methods of their removal, can have an adverse effect on the functional state of the kidneys, which confers a significant medical, social and economic problem. The purpose of this study is to identify factors affecting the functional state of the kidneys in the postoperative period when using various video endoscopic methods of surgical treatment of pa
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Yeremkina, V. I., A. N. Yusupova, and A. I. Menkevich. "Radioisotopic assessment of renal function in early puerperium in women with severe late gestosis of pregnancy." Kazan medical journal 70, no. 5 (1989): 347–48. http://dx.doi.org/10.17816/kazmj101417.

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It is known that late gestosis of pregnant women does not go away, but leaves more or less pronounced changes, particularly in the kidneys. In previous studies we showed that in almost half of women who had severe late gestosis of pregnancy, renal function remains impaired one year after delivery. These abnormalities were detected by radioisotope renography; other diagnostic methods (biochemical, clinical) failed to detect changes in renal function. Unfortunately, radioisotope studies were not performed in early puerperium, so it was not possible to perform dynamic monitoring of the state of r
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42

Smirnov, I., B. Nasibullin, and S. Gushcha. "Assessment of the state of synergies between the structural and functional characteristics of the kidneys and liver during external use of a seaweed product Laminaria algae." Journal of Education, Health and Sport 52 (January 31, 2024): 215–28. http://dx.doi.org/10.12775/jehs.2024.52.108.

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The authors conducted studies to study the relationship between the functional activity of the kidneys, the detoxification activity of the liver and the structural features of the parenchymatous tissue of these organs under normal conditions and with external use of the laminar algae product “Lamidan”. The work was performed on 164 white outbred Wistar rats weighing 180-200 g. The work was carried out in accordance with current standards for working with laboratory animals. The results of many years of research have shown that normally the indicators of detoxification activity of the liver and
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43

Zhmurov, V. A., S. A. Zverev, D. V. Zhmurov, Yu A. Petrova, T. V. Reshetnikova, and E. A. Zhmurova. "The state of kidney function in patients with pulmonary tuberculosis." Medical Science And Education Of Ural 22, no. 3 (2021): 47–50. http://dx.doi.org/10.36361/1814-8999-2021-22-3-47-50.

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Objective: to evaluate the functional state of the kidneys in patients with various clinical variants of pulmonary tuberculosis. Material and methods. 60 patients with pulmonary tuberculosis were examined: 32 people with disseminated forms (53.3%), 16 people with infiltrative pulmonary tuberculosis (26.6%) and 12 people with other forms of pulmonary tuberculosis (20.0%). The average age of patients was 54.3 ± 3.3 years. The examination included a complete clinical, laboratory and instrumental examination. The glomerular filtration rate (GFR) was evaluated using the CKD-EPI formula, followed by
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44

Trajkovic-Arsic, Marija, Theo J. Visser, Veerle M. Darras, et al. "Consequences of Monocarboxylate Transporter 8 Deficiency for Renal Transport and Metabolism of Thyroid Hormones in Mice." Endocrinology 151, no. 2 (2010): 802–9. http://dx.doi.org/10.1210/en.2009-1053.

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Patients carrying inactivating mutations in the gene encoding the thyroid hormone transporting monocarboxylate transporter (MCT)-8 suffer from a severe form of psychomotor retardation and exhibit abnormal serum thyroid hormone levels. The thyroidal phenotype characterized by high-serum T3 and low-serum T4 levels is also found in mice mutants deficient in MCT8 although the cause of these abnormalities is still unknown. Here we describe the consequences of MCT8 deficiency for renal thyroid hormone transport, metabolism, and function by studying MCT8 null mice and wild-type littermates. Whereas s
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45

Chojęta, Dariusz, Małgorzata Maria Kozioł, and Iwona Smarz-Widelska. "Uromodulin – biomarker of renal function with promising clinical application." Medical Science Pulse 14, no. 2 (2020): 1–10. http://dx.doi.org/10.5604/01.3001.0014.3089.

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Uromodulin (also known as Tamm-Horsfall protein) is a glycoprotein produced exclusively in the kidneys, mainly in the epithelial cells of the thick ascending limb of the loop of Henle. Under physiological conditions, it is the most abundant urinary protein. A small proportion is released into the renal interstitium and then into the blood, where it can be detected and used as a potential parameter of renal function. Uromodulin has numerous physiological roles and potential pathogenetic significance, including providing protection against urinary tract infections and the formation of urinary de
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46

Nasibullin, B., S. Gushcha, M. Аrabadji, and V. Stepanova. "Features of the reaction of the kidney function of healthy rats to the intake of boric hydrocarbonate sodium mineral waters of varying quantitative macro- and micro-composition." Journal of Education, Health and Sport 12, no. 6 (2022): 353–64. http://dx.doi.org/10.12775/jehs.2022.12.06.035.

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The purpose of the work is a comparative assessment of the effect of boron hydrocarbonate sodium mineral waters with a varying quantitative and qualitative composition of macroelements and with different amounts of a bioactive element on the state of the urinary system of rats. Materials and methods. The work was performed on 81 white rats of the Wistar line of auto bred breeding, weighing 180-200 g. The rats were divided into four groups: group 1 - 21 intact rats served as controls; group 2 - 20 rats treated intragastrically with a soft probe MW "Polyana Ploskivskaya" at a dose of 1% of body
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47

Sheina, N. I., V. A. Parshin, L. I. Mjalina, L. P. Sazonova, and V. V. Kolesnikova. "PREPARATION «PHYTASE»." Toxicological Review, no. 2 (April 28, 2018): 51–52. http://dx.doi.org/10.36946/0869-7922-2018-2-51-52.

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The preparation “Phytase” is low-toxic, does not have an irritant and sensitizing effect. The threshold of acute inhalation of the preparation is set at the level of 28.0 mg/m3 (on phytase) according to the change in the function of the nervous system and kidneys. Indicative safe exposure level of the preparation “Phytase” in the air of the working area is recommended to be 1.0 mg/m3 (according to phytase), in the atmospheric air of populated areas - 0.02 mg/m3, the aggregate state is aerosol.
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48

Sashnina, L. Yu, A. G. Shakhov, O. A. Manzhurina, V. N. Kotsarev, and G. G. Chusova. "STATE OF PROTEIN METABOLISM IN THE SOWS WITH POSTPARTUM PATHOLOGY." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 60 (2024): 58–62. https://doi.org/10.52368/2078-0109-2024-60-3-58-62.

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The article presents the results of a study on the characteristics of protein metabolism in sows during gestation, lactation and in case of postpartum pathology occurrence. In the animals with postpartum diseases, compared with clinically healthy sows, during all periods of the reproductive cycle, a reduced content of total protein, albumin and urea has been found, which characterizes a less pronounced intensity of protein metabolism. Elevated creatinine levels are caused by insufficient urinary function of the kidneys. The tendency in their proteinogram to increase the content of α-globulins
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49

Kurtz, Armin, and Frank Schweda. "Osmolarity-induced renin secretion from kidneys: evidence for readily releasable renin pools." American Journal of Physiology-Renal Physiology 290, no. 4 (2006): F797—F805. http://dx.doi.org/10.1152/ajprenal.00240.2005.

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Our study aimed to characterize the influence of changes in extracellular osmolarity on renin secretion from the whole kidney. For this purpose, the osmolarity of the perfusion medium of isolated rat or mouse kidneys was either decreased by lowering the NaCl concentration by 20% or was increased up to 133% by the addition of various salts or sugars. It turned out that changes in osmolarity led to instantaneous transient changes followed by a plateau of renin secretion, in that increases in osmolarity stimulated renin secretion, whereas decreases attenuated renin secretion. The peak amplitude o
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50

Van Beek, E., A. J. H. M. Houben, P. N. Van Es, et al. "Peripheral Haemodynamics and Renal Function in Relation to the Menstrual Cycle." Clinical Science 91, no. 2 (1996): 163–68. http://dx.doi.org/10.1042/cs0910163.

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1. The objective of this study was to investigate whether the luteal phase of the menstrual cycle differs from the follicular phase by the development of a state of general vascular relaxation. 2. Once in the follicular and once in the luteal phase of the menstrual cycle, we measured by non-invasive techniques: arterial blood pressure (by finger blood pressure measurements), vascular tone (by pulse-wave velocity and plethysmography), blood flow to skin (by laser-Doppler), blood flow to forearm (by plethysmography) and blood flow to kidneys (by para-aminohippurate clearance), and the glomerular
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