Academic literature on the topic 'Ossification Center'

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Journal articles on the topic "Ossification Center"

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Santhosh, Joy, Sreedevi C.S., and P.A. Manju. "Radiological Study of Appearance and Fusion of Ossification Centers of Elbow Joint." International Journal of Pharmaceutical and Clinical Research 15, no. 1 (2023): 1155–64. https://doi.org/10.5281/zenodo.13162407.

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<strong>Background:&nbsp;</strong>Appearance and fusion of ossification centers like any other biological phenomenon are subject to variation from place to place and race to race. No authentic study on ossification centers has been done in southern Kerala in the last 25 years. In this study, we wanted to determine radiologically the age of appearance and fusion of ossification centers of elbow joint.&nbsp;<strong>Materials and Methods:&nbsp;</strong>This was a hospital based descriptive study conducted among 139 patients(72 males and 67 females) aged between 5 and 19 years who presented with radiographs of elbow joint in anteroposterior and lateral views in each case to the Department of Orthopaedics, Government Medical College, Trivandrum, over a period of 12 months from May 2011 to April 2012 after obtaining clearance from Institutional Ethics Committee and written informed consent from the study participants and the legal guardians.&nbsp;<strong>Results:&nbsp;</strong>Mean age of appearance of ossification center for trochlea was 11.021 years with standard deviation of 0.3219. Sex difference in the appearance of ossification center for trochlea was not statistically significant. Mean age of appearance of ossification center for lateral epicondyle was 12.717 years with standard deviation of 0.5191. Sex difference with respect to appearance of ossification center for lateral epicondyle was not statistically significant. Mean age of formation of conjoint epiphysis was 13.556 years with standard deviation of 0.2396. Sex difference with respect to appearance of ossification center for conjoint epiphysis was not statistically significant. Mean age of complete fusion of conjoint epiphysis was 13.948 years with standard deviation of 0.3534. Sex difference in the fusion of conjoint epiphysis was not statistically significant. Mean age of complete fusion of medial epicondyle was 14.961 years with standard deviation of 0.8291. Sex difference in the fusion of medial epicondyle was not statistically significant. Mean age of complete fusion of Head of radius was 13.948 years with standard deviation of 0.3534.&nbsp;<strong>Conclusion:&nbsp;</strong>Age of appearance of ossification center for capitulum could not be scrutinized as it fell below the lower age limit of sample size. All subjects from 5 to 6 age group onwards showed presence of capitulum. As per the present study, appearance and fusion of ossifications centers are taking place slightly earlier than the existing standards except for appearance of ossification center for medial epicondyle. The enhancement of bone maturity may be due to better nutritional and health standards and changing life styles. Moreover, no subject selected for the study was ill nourished. Sex difference in the appearance and fusion of ossification centers was seen to be statistically insignificant. The age of appearance and fusion of the ossification centers of the elbow joint had shown differences from the conventional values followed for medico legal purpose. &nbsp; &nbsp; &nbsp;
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2

Ivelj, R., M. Leko, and B. Župančić. "Ossification centers in pediatric elbow: a rare normal variant." Paediatria Croatica 55, no. 4 (2011): 289–91. http://dx.doi.org/10.13112/pc.775.

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A 2-year-old girl was brought to our attention due to refusal to use her right arm. Radiographic examination revealed unexpectedly an ossification center of medial epicondyle, even before ossification center of radial head. Taking into account the order of appearance of ossification centers, comparison radiographs of the left elbow were obtained to show an extremely rare variant ossification.
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Grzonkowska, Magdalena, Mariusz Baumgart, Mateusz Badura, Marcin Wiśniewski, and Michał Szpinda. "Quantitative anatomy of the fused ossification center of the occipital squama in the human fetus." PLOS ONE 16, no. 2 (2021): e0247601. http://dx.doi.org/10.1371/journal.pone.0247601.

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CT-based quantitative analysis of any ossification center in the cranium has not previously been carried out due to the limited availability of human fetal material. Detailed morphometric data on the development of ossification centers in the human fetus may be useful in the early detection of congenital defects. Ossification disorders in the cranium are associated with either a delayed development of ossification centers or their mineralization. These aberrations may result in the formation of accessory skull bones that differ in shape and size, and the incidence of which may be misdiagnosed as, e.g., skull fractures. The study material comprised 37 human fetuses of both sexes (16♂, 21♀) aged 18–30 weeks. Using CT, digital image analysis software, 3D reconstruction and statistical methods, the linear, planar and spatial dimensions of the occipital squama ossification center were measured. The morphometric characteristics of the fused ossification center of the occipital squama show no right—left differences. In relation to gestational age, the ossification center of the occipital squama grows linearly in its right and left vertical diameters, logarithmically in its transverse diameters of both the interparietal and supraoccipital parts and projection surface area, and according to a quadratic function in its volume. The obtained numerical findings of the occipital squama ossification center may be considered age-specific references of relevance in both the estimation of gestational age and the diagnostic process of congenital defects.
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Atalgın, Şükrü Hakan, Mustafa Korkmaz, and Kerem Cabas. "Development Status of The Hindlimb Extremity Bones of The Watchdog Hybrid Fetus (40 Days Old)." Harran Üniversitesi Veteriner Fakültesi Dergisi 14, no. 1 (2025): 1–5. https://doi.org/10.31196/huvfd.1537265.

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Hindlimb extremity bones of 40-day-old watchdog hybrid fetuses were examined. Knowing the normal formation of the extremities is important for understanding possible disorders and their treatment. The developmental processes of the movement system do not occur as sequentially as expected. Alizarin red and alcian according to Inouye technique bones of 40-day-old animals were stained with alcian blue. Dissections of bones preserved in appropriate solutions were performed. Stereomicroscopic and normal photographs were taken with a digital camera. Measurements were taken from the dissected legs with a 150 mm Mitutoyo brand caliper. Hindlimb bones of 40-day-old guard dog hybrid fetuses were observed to have primary ossification centers, while some bones had no ossification centers. A primary ossification center was observed in the corpus of the femur, tibia, fibula, and metatarsus bones of the hind limb, while no ossification center was observed in the proximal and distal ends. Also, patella, ossa tarsi, and ossa digitorum pedis no ossification centers were observed.
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Fagin, Bennett D., Everett Aronson, and Mark A. Gutzmer. "Closure of the iliac crest ossification center in dogs: 750 cases (1980-1987)." Journal of the American Veterinary Medical Association 200, no. 11 (1992): 1709–11. http://dx.doi.org/10.2460/javma.1992.200.11.1709.

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Summary Radiographs of 750 dogs were examined to determine whether the iliac crest ossification center was open or closed. The center was closed in most dogs by 2 years of age. Eighteen percent of dogs ≥ 10 years old had open iliac crest ossification center; 10% of dogs ≥ 14 years old had open iliac crest ossification center. Closure of the iliac crest ossification center is extremely variable and, in many dogs, occurs at later age than has been previously reported.
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Kubicek, Kole M. "Developmental osteology of Ictalurus punctatus and Noturus gyrinus (Siluriformes: Ictaluridae) with a discussion of siluriform bone homologies." Vertebrate Zoology 72 (August 12, 2022): 661–727. http://dx.doi.org/10.3897/vz.72.e85144.

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Abstract The skeleton of Siluriformes is characterized by several autapomorphies, including secondary absence, extreme modification, and purported fusion of several ossifications. Although well documented in adults, information on skeletal development in catfishes is relatively sparse and typically focused on particular regions of the skeleton (e.g., Weberian apparatus). To further our understanding of the siluriform skeleton, I document the development of the entire skeleton in two ictalurid species, Ictalurus punctatus (channel catfish) and Noturus gyrinus (tadpole madtom) from five days pre-hatch to adult. I reexamine the homologies of bones previously hypothesized to represent compound elements in catfishes as well as an additional element only known to occur in some ictalurids. Development of the skeleton is complete in I. punctatus at 22.4 mm SL and almost complete in N. gyrinus (except dorsal- and anal-fin distal radials) at 14.1 mm SL. No signs of ontogenetic fusion were observed in any of the purported compound elements. Previous hypotheses of the homology of these elements and of additional ossifications are reviewed in light of developmental information obtained herein. No dermal parietal component is present at any stage in the so-called parieto-supraoccipital. The bone is the supraoccipital which ossifies from two lateral centers of ossification which later fuse, rather than from a median center. The ‘posttemporo-supracleithrum’ originates from a single center of ossification and represents the supracleithrum. The posttemporal is present in ictalurids and many other catfishes as a canal-bearing bone between the supracleithrum and the pterotic, a bone sometimes identified as the extrascapular. The extrascapular is missing in catfishes. Ictalurids have an additional dermal bone above the posttemporal, which is either an independently ossifying fragment of the posttemporal or a neoformation restricted to some members of this family. The single chondral bone of the pectoral girdle originates from a single center of ossification that represents the coracoid. The scapula is missing in catfishes. Dorsal-fin distal radial 2 is absent in catfishes and the foramen of dorsal-fin spine 2 is formed from modifications to the base of the fin-ray itself. Unlike loricarioid catfishes, the urohyal of ictalurids originates solely as an ossification of the sternohyoideus tendons. The anteriormost infraorbital element ossifies from a single center of ossification around the infraorbital sensory canal and represents the lacrimal. The antorbital is missing in catfishes. Finally, skeletal development of I. punctatus is compared to that available for other otophysans, including the cypriniforms Danio rerio and Enteromius holotaenia and the characiform Salminus brasiliensis.
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Kubicek, Kole M. "Developmental osteology of Ictalurus punctatus and Noturus gyrinus (Siluriformes: Ictaluridae) with a discussion of siluriform bone homologies." Vertebrate Zoology 72 (August 12, 2022): 661–727. https://doi.org/10.3897/vz.72.e85144.

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Abstract The skeleton of Siluriformes is characterized by several autapomorphies, including secondary absence, extreme modification, and purported fusion of several ossifications. Although well documented in adults, information on skeletal development in catfishes is relatively sparse and typically focused on particular regions of the skeleton (e.g., Weberian apparatus). To further our understanding of the siluriform skeleton, I document the development of the entire skeleton in two ictalurid species, Ictalurus punctatus (channel catfish) and Noturus gyrinus (tadpole madtom) from five days pre-hatch to adult. I reexamine the homologies of bones previously hypothesized to represent compound elements in catfishes as well as an additional element only known to occur in some ictalurids. Development of the skeleton is complete in I. punctatus at 22.4 mm SL and almost complete in N. gyrinus (except dorsal- and anal-fin distal radials) at 14.1 mm SL. No signs of ontogenetic fusion were observed in any of the purported compound elements. Previous hypotheses of the homology of these elements and of additional ossifications are reviewed in light of developmental information obtained herein. No dermal parietal component is present at any stage in the so-called parieto-supraoccipital. The bone is the supraoccipital which ossifies from two lateral centers of ossification which later fuse, rather than from a median center. The 'posttemporo-supracleithrum' originates from a single center of ossification and represents the supracleithrum. The posttemporal is present in ictalurids and many other catfishes as a canal-bearing bone between the supracleithrum and the pterotic, a bone sometimes identified as the extrascapular. The extrascapular is missing in catfishes. Ictalurids have an additional dermal bone above the posttemporal, which is either an independently ossifying fragment of the posttemporal or a neoformation restricted to some members of this family. The single chondral bone of the pectoral girdle originates from a single center of ossification that represents the coracoid. The scapula is missing in catfishes. Dorsal-fin distal radial 2 is absent in catfishes and the foramen of dorsal-fin spine 2 is formed from modifications to the base of the fin-ray itself. Unlike loricarioid catfishes, the urohyal of ictalurids originates solely as an ossification of the sternohyoideus tendons. The anteriormost infraorbital element ossifies from a single center of ossification around the infraorbital sensory canal and represents the lacrimal. The antorbital is missing in catfishes. Finally, skeletal development of I. punctatus is compared to that available for other otophysans, including the cypriniforms Danio rerio and Enteromius holotaenia and the characiform Salminus brasiliensis.
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Grzonkowska, Magdalena, Mariusz Baumgart, Michał Kułakowski, and Michał Szpinda. "Quantitative anatomy of the primary ossification center of the squamous part of temporal bone in the human fetus." PLOS ONE 18, no. 12 (2023): e0295590. http://dx.doi.org/10.1371/journal.pone.0295590.

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Detailed numerical data about the development of primary ossification centers in human fetuses may influence both better evaluation and early detection of skeletal dysplasias, which are associated with delayed development and mineralization of ossification centers. To the best of our knowledge, this is the first report in the medical literature to morphometrically analyze the primary ossification center of the squamous part of temporal bone in human fetuses based on computed tomography imaging. The present study offers a precise quantitative foundation for ossification of the squamous part of temporal bone that may contribute to enhanced prenatal care and improved outcomes for fetuses with inherited cranial defects and skeletodysplasias. The examinations were carried out on 37 human fetuses of both sexes (16 males and 21 females) aged 18–30 weeks of gestation, which had been preserved in 10% neutral formalin solution. Using CT, digital image analysis software, 3D reconstruction and statistical methods, the size of the primary ossification center of the squamous part of temporal bone was evaluated. With neither sex nor laterality differences, the best-fit growth patterns for the primary ossification center of the squamous part of temporal bone was modelled by the linear function: y = −0.7270 + 0.7682 × age ± 1.256 for its vertical diameter, and the four-degree polynomial functions: y = 5.434 + 0.000019 × (age)4 ± 1.617 for its sagittal diameter, y = −4.086 + 0.00029 × (age)4 ± 2.230 for its projection surface area and y = −25.213 + 0.0004 × (age)4 ± 3.563 for its volume. The CT-based numerical data and growth patterns of the primary ossification center of the squamous part of temporal bone may serve as age-specific normative intervals of relevance for gynecologists, obstetricians, pediatricians and radiologists during screening ultrasound scans of fetuses. Our findings for the growing primary ossification center of the squamous part of temporal bone may be conducive in daily clinical practice, while ultrasonically monitoring normal fetal growth and screening for inherited cranial faults and skeletodysplasias.
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Watson, Alastair G., and James S. Stewart. "Postnatal ossification centers of the atlas and axis in Miniature Schnauzers." American Journal of Veterinary Research 51, no. 2 (1990): 264–68. http://dx.doi.org/10.2460/ajvr.1990.51.02.264.

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SUMMARY Postnatal ossification of the atlas and axis was studied in Miniature Schnauzers by examining alizarin-stained bone clearings, cleaned dry bones, radiographs, histologic sections, and arterially perfused bone clearings. Sixty-two pups (1 day to 16 weeks old) and 4 adults were examined. In 1-day-old pups, the atlas consisted of 3 separate ossification centers: a left and right neural arch center and midventrally, the intercentrum 1, which formed the body of the atlas. The axis contained 4 separate ossification centers: a left and right neural arch center; centrum 2 in the main part of the axis body; and centrum 1, which formed the caudal part of the dens and the cranial part of the axis body. By 6 weeks of age, the epiphysis on the caudal end of the axis body had begun to ossify. At this time, the intercentrum 2, which developed as a cuboidal ossification center intercalated between centrum 1 and centrum 2 in the middle of the cranial half of the axis body, also began to ossify. The centrum of the proatlas, which formed the apex of the dens, was first seen ossified in a 9-week-old pup. These 10 ossification centers were seen as constant and separate elements. In all dogs, the dens developed from 2 separate ossification centers: the centrum of the proatlas formed the cranial one-quarter, and centrum 1 formed the caudal three-quarters. Dens dysplasia is unlikely to be a result of failure of development of one of the ossification centers for the dens. Seemingly, vascular-related ischemia may lead to postnatal resorption of at least the middle part of the dens and result in dens dysplasia, with subsequent atlantoaxial subluxation. This condition in dogs may be a suitable animal model for the study of the pathogenesis of os odontoideum and related conditions in man.
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Chhaya, Rani, Kumar Nilesh, and Kumar Sinha Sanjay. "Radiological Study of Secondary Ossification Centers around the Elbow Joint in North Bihar." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 869–75. https://doi.org/10.5281/zenodo.12582821.

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<strong>Background:&nbsp;</strong>The bones of human skeletons develop from separate Ossification centers. From these centers ossification progresses till the bone is completely formed. These Changes can be studied by means of x-rays. It is therefore possible to determine the approximate age of an individual by radiological examination of bones till ossification is complete.&nbsp;<strong>Materials &amp; Methods:&nbsp;</strong>This radiological study was carried out with the objective to assess the skeletal maturity round elbow joint, of subjects in North Bihar region, 168 Males and 132 Females between age group of 10-19 years and size of dwelling in North Bihar more than 10 years. Subjects representing the heterogenous population of Bihar were included from first year MBBS students of Katihar Medical College, Katihar of different districts of this state, schools as well as patients attending outpatients Department of Radiology, Katihar. Medical College, Katihar Anteroposterior and lateral view of Right elbow joint was taken, appearance and fusion of ossification centers around this joint studied. Data was tabulated and statistically analysed by using STATA 12.0 TX, USA.&nbsp;<strong>Results:&nbsp;</strong>From the analysis, it is found that in males at the age of 16 years, ossification centers around the elbow joint is fused except medial epicondyle and in females, it is completely fused.&nbsp;<strong>Conclusion:&nbsp;</strong>From this radiological study, when findings are compared with the other authors from different states of India and in addition with other nations and observed to Fluctuate substantially. &nbsp; &nbsp; &nbsp;
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Dissertations / Theses on the topic "Ossification Center"

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Moioli, M. "APPEARANCE OF OSSIFICATION CENTERS OF THE LIMBS AND SKELETAL DEVELOPMENT IN NEWBORN TOY-DOG BREEDS: RADIOGRAPHIC, MORPHOMETRIC AND HISTOLOGICAL ANALYSIS." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/233994.

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The study aims to find out the chronological appearance of the ossification centers of appendicular skeleton of newborn toy-breed dogs during the first month of life and to correlate the data obtained with morphometric measures of the skeleton by radiological and anatomical approach. Data obtained were implemented with bone mineral density (BMD) analysis of the long bones and histological and histochemical analysis of limbs bone sections, to evaluate and quantify the trends of the ossification process and the architectural changes of ossification centers. The study was carried out in 37 newborn toy-breed dogs <28 days old, spontaneously died for unrelated reasons with this study, divided into 4 groups on the basis of age (first week, second week, third week and fourth week). The forelimbs and the hind limbs have been evaluated by radiological and histological analysis. Long bones, cranial and body measurements, both radiological and anatomical, were taken and the BMD of radius and ulna and of os femoris was calculated. The results have been correlated through statistical analysis and compared with standard charts proposed by Literature in order to assess significant differences with medium and large breed dogs. The appearance of most of the ossification centers reflects the timing of ossification of medium and large breed dogs, however the behavior of some ossification centers changes and therefore might be considered typical of toy-dog breeds. Femoral length could be taken into consideration as a parameter to assess the developmental rate and the age of toy-breed dogs during the growing period, particularly in the first 4 weeks of age. Increasing BMD is highly correlated with increasing long bones length and seems to confirm the space-time relationship between BMD in canine newborn skeleton and in long bones growth. The radiological, histological and bone mineral density analysis and the correlations between long-bones length, skull diameters, age and body mass, might be currently appropriate to determine the skeletal age in newborn toy-dog breeds.
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Randazzo, Loredana Antonella. "The behaviour of trace elements during the volcanic ash-liquid interaction : example of marine and human systems." Thesis, Lyon 1, 2011. http://www.theses.fr/2011LYO10051.

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Les processus d’interaction solide-liquide régulent les mécanismes qui régissent la disponibilité des oligo-éléments en phase liquide. Dans cet article, ces processus ont été étudiés grâce à l'utilisation des éléments de terres rares (REE), car ils sont d'excellents traceurs des processus géochimiques. Le but de la première partie de ce travail était d'étudier la réactivité des particules volcaniques lors de l'interaction avec l'eau de la mer synthétique. Les résultats montrent que en dehors de la dissolution, qui est le processus principal, un procédé d'adsorption de surface se produit également, probablement sur la surface des cristaux nouvellement formé. La présence supposée de ces minéraux est suggéré par la variation temporelle de l'Y/Ho, des observations SEM et analyse XRD. Enfin, l'ajout des ligand dissous ne pas augmenter le taux de dissolution des particules volcaniques, mais modifiant la distribution de REE en phase liquide. Dans la deuxième partie de ce travail, l'étude des terres rares a été appliquée à un système humain. Ces éléments ont été utilisés, en fait, d'enquêter sur les fluides du poumon (BAL) chez les personnes exposées aux retombées de cendres volcaniques. Le résultat suggère que la co-précipitation du YLn-phosphates se produisent dans les poumons, à la suite de l'inhalation de particules volcaniques. Ce processus est confirmé par des simulations thermodynamiques et cinétiques indiquant que la cristallisation de YLn-phosphates et d'autres phases authigènes apparaît comme la conséquence de la dissolution de la fraction solubles de cendres<br>The solid-liquid interaction processes regulate the mechanisms governing the availability of trace elements in liquid phase. In this paper, these processes have been studied through the use of the Rare Earth Elements (REE) since they are excellent tracers of geochemical processes. The purpose of the first part of this work was to study the reactivity of volcanic particulates during the interaction with synthetic seawater. The results show that apart from the dissolution, which is the main process, a surface adsorption process also occurs, probably on the surface of newly formed crystals. The supposed presence of these minerals is suggested by the temporal variation of the Y/Ho ratio, by SEM observations and XRD analysis. Finally the addition of ligand species to dissolved media does not increase dissolution rate of volcanic particles but modify the YLn distribution in liquid phase. In the second part of this work, the Rare Earth study was applied to a human system. These elements were used, in fact, to investigate the effects due to the interactions between the inhaled atmospheric particulate matter and the lung fluids (BAL), in people exposed to fallout of volcanic ash. The results suggest that YLn-phosphate co-precipitation occurs in lungs as a consequence of inhalation of volcanic particles and their interactions with lung fluids. This process is confirmed by thermodynamic and kinetic simulations indicating that crystallisation of YLn-phosphates and other authigenic phases occurs as a consequence of the soluble ash fraction dissolution. The combination of YLn fractionation in bronchial fluids can represent a potential tracer of exposure to atmospheric fallout
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Meloni, T. "SOME PERINATAL ENDOCRINE AND MORPHOLOGICAL ASPECTS OF CANINE SPECIES." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/265723.

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Despite the huge literature about dog medicine, the perinatal period of growth and development and possible perturbations of the health of fetuses and newborns are still scarcely investigated, but with a recent, increasing scientific interest. The present thesis was therefore aimed to investigate some perinatal aspects of canine perinatology. Firstly, the study focused on the presence of some growth and metabolic factors and protective substances in dog fetal fluids at term of normal pregnancy. About growth and metabolic factors, the first study showed that insulin-like growth factors I (IGF-I) were higher in amniotic (AM) than allantoic (AL) fluid and the effect of breed size, even if opposite, on both IGF-I and non-esterified fatty acids (NEFA) was evidenced. The findings suggested that AM IGF-I could be used as an indicator of growth potential in canine species, whereas AM NEFA could work as a marker of fat mobilization for an energy request. The second study on fetal fluids, aimed to assess AM and AL IgG and lysozyme concentrations, documented higher IgG levels in AM than AL fluid, as a consequence of a supposed direct fetal IgG production, whereas no significant differences were found in lysozyme values between the two fluids. Maternal parity was demonstrated to affect IgG concentrations. A second area of study was the assessment of newborns hair and nails usefulness as the newest non invasive matrices for a long-term retrospective investigation of the Hypothalamic-Pituitary-Adrenal axis activation, by cortisol (C) concentrations analysis. The study evidenced that C was detectable in both matrices, with significant higher values in premature puppies compared to term-born dead puppies or puppies dead within the first 30 days of age. Furthermore, because of the newborn puppy high susceptibility to bacterial infection, often followed by death, the fourth study investigated the bacterial involvement in canine neonatal mortality, demonstrating that bacterial infections, above all by E. coli, alone or in association with other bacteria, represent an important cause of neonatal losses. In addition, the study highlighted the importance of the antimicrobial susceptibility test in case of suspected neonatal bacterial infection for a more targeted therapy of surviving litter-mates and for a better management of further gestations in bitch with previous neonatal mortality. The last study was designed to investigate some aspects of skeletal development during the neonatal period in the attempt to provide further knowledge about the first month of skeletal growth in puppies, but also aimed to assess the possible use of some radiographic, morphometric, and anatomic parameters for the age estimation in newborn dogs. The study proved that the neonatal growth occurs gradually as the age progresses, and simultaneously in the body, limbs, and skull. The radiographic evaluation of the ossification centers appearance resulted a useful tool to estimate the neonatal age in puppies, even if during the first 14 days of age significant skeletal changes were not observed. In this respect, the radiographic and anatomic measures of the hindlimb long bones and skull length seem to provide better guarantees; specifically, the neurocranium width as well as tibial and femoral lengths resulted the most correlated measurements with the age. Thus, in the future radiographic and/or anatomical morphometry of limbs and skull could become the best tool for neonatal age estimation.
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Phillips, Vincent Michael. "Dental maturation of the permanent mandibular teeth of South African children and the relation to chronological age." Thesis, 2009. http://hdl.handle.net/11394/3425.

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Philosophiae Doctor - PhD<br>Age estimation of the skeletal remains of children can be accomplished by examination of the ossification centres and the fusion of the epiphyseal plates of long bones. Dental age estimation is done by examining the eruption of the deciduous and permanent teeth. Both these methods are inaccurate and are subject to the nutritional status of the individual. A more accurate method of age estimation is by the examination of radiographic images of the developmental stages of the tooth crown and root formation. Two methods of dental age estimation used are those of Moorrees, Fanning and Hunt (1963) (MFH) and that of Demirjian, Goldstein and Tanner (1973) (DGT). These methods were tested on a sample of 913 Tygerberg dental patients; a random mixture of Caucasoid and Khoisanoid children. The MFH method under-estimated the ages of the sample by an average of 0.91 years and the DGT method over-estimated the ages by an average of 0.89 years. Samples of Indian and Negroid children from Kwa-Zulu Natal were tested in a similar manner and the results showed similar under and over-estimation of the ages by these methods. The Negroid children were labelled the Zulu sample. Correction factors were derived for the MFH and DGT methods of dental age estimation when used on Tygerberg, Indian and Zulu children. These correction factors were tested on the samples and found to improve the accuracy of the age estimation methods of MFH and DGT significantly.A second sample group of Tygerberg, Indian and Zulu children were then tested firstly using the standard method of MFH and DGT and the using the correction factors. The results showed that the correction factors improved the age estimation on these samples except in the case of the DGT method on Zulu children. A sample of Xhosa speaking children were added to the two Zulu samples and made an Nguni sample. The Tygerberg samples were combined as were the Indian samples to form data bases for the construction of dental age related tables for Tygerberg, Indian and Nguni children. These tables show that there are distinct differences in the ages at which the teeth develop in the different sample groups and that dental age related tables are necessary for children of different population origins. Statistical analysis of the age related tables from this study (Phillips Tables) show these tables are more accurate in the age estimation of South African children.
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Books on the topic "Ossification Center"

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Oddy, M. J., and Deborah M. Eastwood. Foot injuries in children. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.014011.

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♦ The child’s foot is very supple but when injuries do occur conventional imaging is not as valuable as it should be because of the late ossification. Accessory centres of ossification complicate matters♦ Transchondral fractures are not easily seen on conventional x-rays♦ Lawnmower injuries (shredding of the forefoot) should have a slightly more tissue-preserving approach than in adults♦ Lacerated tendons in the hindfoot need repairing if foot growth is to be normal.
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Book chapters on the topic "Ossification Center"

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Zhang, Minqing, Dijia Wu, Qin Liu, Qingfeng Li, Yiqiang Zhan, and Xiang Sean Zhou. "Multi-Task Convolutional Neural Network for Joint Bone Age Assessment and Ossification Center Detection from Hand Radiograph." In Machine Learning in Medical Imaging. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-32692-0_78.

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Krstić, Radivoj V. "Bony Tissue. Indirect or Chondral Bone Formation. Epiphyseal Ossification Centers and Epiphyseal Plate. Continuation of Plate 99." In General Histology of the Mammal. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70420-8_101.

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Bashir, Ayesha, Qurrat ul Ain, and Naveeda Bashir and Wajahat Sohail. "Bone Development and Growth." In Innovation in Osteogenesis Research [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1005118.

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Osteogenesis is a complex process of bone formation involving several phases and utilizes various cell, metabolites, hormones, and organic and inorganics components. Numerous genetic factors mediate bone formation. Initially, progenitor cells produce osteoblastic lines, which pass through three major cell differentiation stages: proliferation, maturation of matrix, and mineralization. Based on embryonic origin, ossification is of two types: intramembranous and endochondral. In intramembranous ossification, mesenchymal cells in ossification center directly differentiate into osteoblasts, without prior cartilage formation. It involves mesenchymal cell proliferation in highly vascularized areas of embryonic connective tissue, leading to primary ossification center formation. These cells then synthesize bone matrix at periphery, with continuous differentiation into osteoblasts. The resulting bone undergoes reshaping and is eventually replaced by mature lamellar bone. Sufficient blood supply and communication among cells by lacunar-canalicular system are crucial for bone synthesis and maintenance. In contrast, endochondral ossification begins with the formation of primary ossification center within cartilage. Chondrocytes undergo proliferation, expanding the cartilage through cartilage matrix deposition. Central region of cartilage sees the maturation of chondrocytes into hypertrophic chondrocytes. As primary ossification center forms, marrow cavity expands toward epiphysis. The process is completed by subsequent stages of endochondral ossification in various zones of ossification.
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Singh, Hariqbal, and Shrikant Nagare. "Ossification Centers." In Textbook of Radiology: Musculoskeletal Radiology. Jaypee Brothers Medical Publishers (P) Ltd., 2017. http://dx.doi.org/10.5005/jp/books/12944_12.

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Singh, Hariqbal, and Parvez Sheik. "Ossification Centers." In Atlas on X-ray and Angiographic Anatomy. Jaypee Brothers Medical Publishers (P) Ltd., 2013. http://dx.doi.org/10.5005/jp/books/11906_9.

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Singh, Hariqbal, Anubhav Khandelwal, and Sushil Kachewar. "Ossification Centers." In Atlas of Human Anatomy on CT Imaging. Jaypee Brothers Medical Publishers (P) Ltd., 2010. http://dx.doi.org/10.5005/jp/books/11180_11.

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Singh, Hariqbal, and Parvez Sheik. "Ossification Centers." In Atlas of Human Anatomy on MRI Spine Extremities Joints. Jaypee Brothers Medical Publishers (P) Ltd., 2011. http://dx.doi.org/10.5005/jp/books/11253_14.

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Lima, Larissa Luana Lopes, Regina Moura de Oliveira, Ana Hester Silva Santos, et al. "Incidence of metopism in dried skulls of adults from the osteological collection of the faculty of medicine of FAP-Araripina (PE)." In Health and Medicine: Science, Care, and Discoveries. Seven Editora, 2023. http://dx.doi.org/10.56238/sevened2023.004-018.

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During fetal life and childhood, the bones of the skull and face are separated by dense connective tissue membranes with large amounts of collagen fibers that constitute the sutures. One of these is the metopic suture, which joins the two frontal bones in the embryonic period and in the newborn. This suture appears approximately at the end of the second month of intrauterine life between the two ossification centers of the frontal bone, being considered as an anterior extension of the sagittal suture and its total fusion can occur from the end of the first year to the eighth or tenth year of life. , and may persist in adults. The objective of our study was to verify the incidence of metopic suture in dry skulls of adults in the Northeast region of Brazil. A sample of 474 dry skulls of adults, 294 male and 180 female, belonging to the Forensic Anthropology Center of the Faculty of Medicine of FAP-Araripina was used. In general, 84.6% of the skulls did not have a persistent metopic suture, with 3.6% having a complete metopic suture, 10.3% an incomplete metopic suture of the nasion type and 1.5% an incomplete metopic suture of the nasion type. bregma type. Complete metopic suture was more frequent in males (2.3%) than in females (1.3%). Due to the large territorial extension of Brazil and the great miscegenation of the population, in our view, it is necessary to carry out more studies in Brazilian individuals through dry skulls or images, especially if carried out in different regions of our country.
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"Epiphysis: Supernumerary Epiphyseal Ossification Centers." In Differential Diagnosis in Pediatric Imaging, edited by Rick R. van Rijn and Johan G. Blickman. Georg Thieme Verlag, 2011. http://dx.doi.org/10.1055/b-0034-87930.

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Morrey, Bernard F. "Loose Bodies and Ossification Centers About the Elbow." In Morrey's the Elbow and its Disorders. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-323-34169-1.00084-x.

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Conference papers on the topic "Ossification Center"

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Garzón-Alvarado, D. A., and L. M. Peinado-Cortés. "Appearance and Development of Secondary Ossification Center: A Mathematical Model Approach." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19648.

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This paper introduces an “hypothesis about the growth pattern of the secondary ossification centre (SOC)”, whereby two phases are assumed. First, the formation of cartilage canals as an event essential for the development of the SOC. Second, hence the canals are merged in the central zone of the epiphysis, molecular factors are released (primarily Runx2 and MMP9) spreading and causing hypertrophy of adjacent cells. In order to test this hypothesis we solve a system of coupled partial differential equations using the finite element method and we have obtained spatio-temporal patterns of the growth process of the SOC. The model is in qualitatively agreement with experimental results previously reported by other authors.
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Mahmoodian, Roza, and Sorin Siegler. "An MRI Based Study of Tarsal Development During Manipulation and Casting Therapy of Infant Clubfoot." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-42573.

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Ponseti technique is a common non-surgical treatment based on serial manipulation and casting for idiopathic infant clubfoot. We have used three dimensional MRI throughout the treatment, to investigate the effect of the casts on the clubfoot of a one week old (at the beginning of treatment) male with unilateral right idiopathic congenital clubfoot deformity. A total of 21 MRI scans were obtained during weekly serial manipulation and corrective casting. Changes in shape, volume, ossification, and positional relationships of the hind foot anlagen were studied. We found that immediate shape changes occur following casting, particularly in the talus and the navicular, and when after one week the cast is removed the anlagen do not elastically return to their original shape and position prior to casting. Furthermore, the growth rate of some of the clubfoot anlagen, in particular the talus, was faster than normal. A faster ossification was observed in the calcaneus and cuboid. Results also showed correction in parallelism of calcaneus and talus in the anteroposterior plane, minor correction of this parallelism in the lateral view necessitating a heel cord tenotomy, and correction of the medial rotation of calcaneus. Under this treatment changes in talar neck angle yielded a decreasing trend. The navicular moved with respect to the head of the talus from a medial to a lateral position. Relative to the talar body it shifted laterally. Also the geometrical center of talus ossific nucleus was noted to move towards the center of the whole anlagen suggesting that the ossification extends in the opposite direction from the head of the talus. It was concluded that the mechanism of adaptation to the casting loads was quick deformation immediately upon cast application followed by adaptation to the new shape in the cast. These were qualitative findings. It was also concluded that most of the correction occurred during the initial treatment period, primarily during the first and second weeks (1). On the quantitative end, it was confirmed that MRI and computer techniques can be utilized to ascertain and quantify the abnormalities which were impossible to well identify otherwise. MRI based studies have powerful potential to provide helpful information on the choice of treatment as well as guidance throughout. For instance, it may therefore be possible in the present case to shorten the treatment time without adverse effects on the outcome.
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Williams, John L., Nicholas K. Gove, G. Adam Flowers, and Thomas L. Schmidt. "Fracture Toughness of the Growth Cartilage Reserve Zone Is Anisotropic." In ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/bed-23066.

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Abstract In the developing proximal tibial epiphysis the anterior ossifying tibial tuberosity is separated from the secondary ossification center of the tibial epiphysis by a bipolar growth plate known as the ‘cartilage bridge.’ We tested the fracture toughness of the central part of this growth cartilage in 18-week old calves in the direction perpendicular to the plate (mean 4962 N/m, SD 1846) and found it to be greater (p = 0.0004) than in the parallel direction (mean 2909 N/mm, SD 1122). Part of the reason for this anisotropy is the presence of vascular channels which cross the bridge from the epiphysis into the tuberosity. In addition, we hypothesize that the anisotropy reflects an arrangement of collagen primarily along the length of the ‘cartilage bridge.’
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Lee, Chanyoung, Joan T. Richtsmeier, and Reuben H. Kraft. "A Multiscale Computational Model for the Growth of the Cranial Vault in Craniosynostosis." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-38728.

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Craniosynostosis is a condition defined by premature closure of cranial vault sutures, which is associated with abnormalities of the brain and skull. Many causal relationships between discovered mutations and premature suture closure have been proposed but an understanding of the precise mechanisms remains elusive. This article describes a computational framework of biological processes underlying cranial growth that will enable a hypothesis driven investigation of craniosynostosis phenotypes using reaction-diffusion-advection methods and the finite element method. Primary centers of ossification in cranial vault are identified using an activator-substrate model that represents the behavior of key molecules for bone formation. Biomechanical effects due to the interaction between growing bone and soft tissue is investigated to elucidate the mechanism of growth of cranial vault.
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