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Journal articles on the topic 'Osteoarthritis Drugs'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ghosh, P. "Chondroprotective drugs and osteoarthritis." Annals of the Rheumatic Diseases 49, no. 5 (1990): 338–39. http://dx.doi.org/10.1136/ard.49.5.338-c.

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2

Matthews, Gloria L., and David J. Hunter. "Emerging drugs for osteoarthritis." Expert Opinion on Emerging Drugs 16, no. 3 (2011): 479–91. http://dx.doi.org/10.1517/14728214.2011.576670.

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3

Russo, Rosita, Valentina Vassallo, Antonietta Stellavato, et al. "Differential Secretome Profiling of Human Osteoarthritic Synoviocytes Treated with Biotechnological Unsulfated and Marine Sulfated Chondroitins." International Journal of Molecular Sciences 21, no. 11 (2020): 3746. http://dx.doi.org/10.3390/ijms21113746.

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Symptomatic slow-acting drugs (SYSADOA) are increasingly used as effective therapies for osteoarthritis, representing an attractive alternative to analgesics or non-steroidal anti-inflammatory drugs to relieve disease symptoms. Pharmaceutical preparations of chondroitin sulfate, derived from animal sources, alone or in combination with glucosamine sulfate, are widely recognized for their beneficial effect on osteoarthritis treatment. A growing interest has also been devoted to understanding the molecular mechanisms modulated by SYSADOA using -omic strategies, most of which rely on chondrocytes

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4

Sah, Govinda, and Bindu Malla. "Analysis of Prescribing Patterns of Drugs Used in Osteoarthritis in Tertiary Care Center." Journal of Drug Delivery and Therapeutics 14, no. 10 (2024): 10–17. http://dx.doi.org/10.22270/jddt.v14i10.6811.

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Background: Osteoarthritis (O.A.) is a common degenerative lesion of the articular cartilage that corresponds to hypertrophy deterioration of bone structure is osteoarthritis. The treatment is mainly focused on the management of pain. Methods: An Observational study was conducted among 163 patients visiting Orthopedics Out Patient Department at GMC Hospital. The duration of study was for 6 months from Jan 2024-Jun 2024. The analysis of collected data was done by SPSS version Software. Descriptive Statistics tools like frequency, Percentage were used to express the findings. Results: We found t

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5

Shavlovskaya, O. A. "Bioregulatory drugs in osteoarthritis management." Medical Council, no. 1 (March 6, 2019): 76–83. http://dx.doi.org/10.21518/2079-701x-2019-1-76-83.

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Osteoarthritis (OA) is a degenerative joint disease. Modern theories consider various structural (cartilage destruction) and biophysical disorders (matrix loss of glycosaminoglycans) as the basis of acute and chronic pain syndrome. The main aim of OA therapy is pain relief and functional improvement. To manage pain syndrome in OA it is reasonable to use complex bioregulatory drugs (CBD) (Traumeel S, Zeel T, Discus compositum) both in monotherapy and in combined treatment. The effectiveness of CBD is comparable to that of NSAIDs and CS.

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6

Meera, Muthu. "Recent advances in the pharmacotherapy of osteoarthritis." Research Results in Pharmacology 8, no. (4) (2022): 167–74. https://doi.org/10.3897/rrpharmacology.8.84951.

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Introduction: Osteoarthritis (OA) is a common debilitating disease affecting the geriatric population. Management of osteoarthritis is a challenge for orthopedicians because till date there has been no such drug that can completely cure the disease or at least retard/arrest the disease progression. In addition to the currently available treatment options for OA like NSAIDs, opioids, nutraceuticals (glucosamine sulphate and chondroitin sulphate), many new drugs are being discovered or repurposed for use in osteoarthritis. Most of these recent drugs aim at retarding the disease progression rathe

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7

Song, Yingzhuo, Tao Zhang, Huiguang Cheng, et al. "Imidazolium-Based Ionic Liquid-Assisted Preparation of Nano-Spheres Loaded with Bio-Active Peptides to Decrease Inflammation in an Osteoarthritis Model: Ex Vivo Evaluations." Journal of Biomedical Nanotechnology 17, no. 5 (2021): 859–72. http://dx.doi.org/10.1166/jbn.2021.3069.

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Osteoarthritis is one of the most prevalent chronic diseases. Cartilage inflammation in osteoarthritis results from pain in articular joints. Anti-inflammatory drugs provide relief by hindering the production of pro-inflammatory cytokines and interleukin-6. Targeted delivery of anti-inflammatory drugs is very effective in the treatment of osteoarthritis. This approach reduces the usage of therapeutic drug dosages and unwanted side effects. Here, we fabricated a non-invasive and efficient targeted drug delivery system to reduce persistent inflammation in an osteoarthritis model. Temperature-sen

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8

Park, Junyong, and Sung Won Lee. "Efficacy of disease-modifying osteoarthritis drugs in the treatment of osteoarthritis." Journal of the Korean Medical Association 67, no. 10 (2024): 641–48. http://dx.doi.org/10.5124/jkma.2024.67.10.641.

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Background: Osteoarthritis is the most common form of chronic inflammatory arthritis, and its prevalence is steadily increasing owing to its association with aging. Therefore, understanding and implementing appropriate treatments for osteoarthritis in clinical practice is becoming increasingly important. Additionally, there is active research on a new approach for treating osteoarthritis: disease-modifying osteoarthritis drugs (DMOADs).Current Concepts: Several global osteoarthritis treatment guidelines exist; this article introduces the guidelines of the American College of Rheumatology and O

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9

Nasreen, Sulthana*and K.Vijaya. "PREVENTION OF NEPHROTOXICITY BY CURCUMIN IN CHEMICALLY INDUCED OSTEOARTHRITIS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1822–30. https://doi.org/10.5281/zenodo.1210845.

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Osteoarthritis is a degenerative disorder resulting in degeneration of cartilage and osteophytes formation. Non steroidal anti inflammatory drugs are commonly used drugs to alleviate the pain in most of the chronic inflammatory conditions like osteoarthritis. These drugs alleviate the pain by inhibiting the synthesis of prostaglandins. Although these drugs reduce the pain, they have several limitations as they cause nephrotoxicity. In recent years several works have been carried out to improve the therapeutic strategy in osteoarthritis. The present study was carried out to investigate the role

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10

Zvekic-Svorcan, Jelena, Ivana Minakovic, Ksenija Boskovic, Dusica Simic-Panic, Jelena Mikov, and Natasa Igic. "Pharmacological osteoarthritis therapy and modern therapeutic principles." Medical review 75, Suppl. 2 (2022): 47–52. http://dx.doi.org/10.2298/mpns22s2047z.

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Introduction. The purpose of treating osteoarthritis is to relieve pain, improve the function of the osteoarthritic joint, and arrest further development of osteoarthritis through non-pharmacological and pharmacological treatment modalities. Pharmacological osteoarthritis therapy. In the treatment of osteoarthritis, guidelines and recommendations are often consulted, but they do not dictate the treatment mode, which is tailored to the individual needs of the patient. These guidelines promote desired and positive treatment outcomes, but cannot predict a specific outcome. They are also valuable

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11

Meera, Muthu. "Recent advances in the pharmacotherapy of osteoarthritis." Research Results in Pharmacology 8, no. 4 (2022): 167–74. http://dx.doi.org/10.3897/rrpharmacology.8.84951.

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Introduction: Osteoarthritis (OA) is a common debilitating disease affecting the geriatric population. Management of osteoarthritis is a challenge for orthopedicians because till date there has been no such drug that can completely cure the disease or at least retard/arrest the disease progression. In addition to the currently available treatment options for OA like NSAIDs, opioids, nutraceuticals (glucosamine sulphate and chondroitin sulphate), many new drugs are being discovered or repurposed for use in osteoarthritis. Most of these recent drugs aim at retarding the disease progression rathe

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12

Patil, Lokesh V., and Manisha Nara. "A prospective observational study of prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 6, no. 1 (2016): 85. http://dx.doi.org/10.18203/2319-2003.ijbcp20164757.

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Background: Treatment of Osteoarthritis aims at reducing pain and improving mobility. NSAIDS are commonly prescribed for symptomatic relief despite well documented adverse effects. Paracetamol with its better safety profile is recommended as the initial analgesic of choice. Osteoarthritis has significant socio-economic impact on the patients and not many studies are available to reflect upon the prescription pattern of drugs in Osteoarthritis. Hence, this study was chosen to generate important feedback to the clinician. The objectives of the study were to study the prescribing pattern of drugs

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13

Oo, Win Min. "Prospects of Disease-Modifying Osteoarthritis Drugs." Clinics in Geriatric Medicine 38, no. 2 (2022): 397–432. http://dx.doi.org/10.1016/j.cger.2021.11.010.

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14

&NA;. "Using COX-2 Drugs for Osteoarthritis." Nurse Practitioner 27, no. 10 (2002): 49. http://dx.doi.org/10.1097/00006205-200210000-00013.

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15

Oo, Win Min. "Prospects of Disease-Modifying Osteoarthritis Drugs." Rheumatic Disease Clinics of North America 50, no. 3 (2024): 483–518. http://dx.doi.org/10.1016/j.rdc.2024.03.003.

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16

Apostu, Dragos, Ondine Lucaciu, Alexandru Mester, et al. "Systemic drugs with impact on osteoarthritis." Drug Metabolism Reviews 51, no. 4 (2019): 498–523. http://dx.doi.org/10.1080/03602532.2019.1687511.

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17

JANCIN, BRUCE. "Osteoarthritis Drugs Offer Minimal Pain Relief." Internal Medicine News 39, no. 19 (2006): 36. http://dx.doi.org/10.1016/s1097-8690(06)74294-9.

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18

Isyna Hida and Rismi Fatoni. "Gambaran Penggunaan Obat Antiinflamasi Non Steroid Pada Pasien Penderita Osteoarthritis di Instalasi Rawat Jalan RSUD Kajen Periode Januari – Oktober 2024." An-Najat 3, no. 1 (2025): 19–34. https://doi.org/10.59841/an-najat.v3i1.2239.

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Basic Health Research data in 2018 recorded that the rate of osteoarthritis sufferers in Central Java was around 6.78% and the rate of osteoarthritis sufferers in Pekalongan Regency was around 5.37%. Treatment of osteoarthritis can be done pharmacologically by administering non-steroidal anti-inflammatory drugs. The purpose of this study is to find out the description of the use of non-steroidal anti-inflammatory drugs in patients with osteoarthritis in the outpatient unit of Kajen Hospital, Pekalongan Regency. This type of research is non-experimental using a descriptive design with a quantit

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19

Fatenko, A., and Elena Belyaeva. "Modern views on osteoarthritis therapy." Clinical Medicine and Pharmacology 7, no. 3 (2021): 38–40. http://dx.doi.org/10.12737/2409-3750-2021-7-3-38-40.

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20

Kriplani, Priyanka, Kumar Guarve, and Uttam Singh Baghel. "Novel Herbal Topical Patch Containing Curcumin and Arnica montana for the Treatment of Osteoarthritis." Current Rheumatology Reviews 16, no. 1 (2020): 43–60. http://dx.doi.org/10.2174/1573397115666190214164407.

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Background: Osteoarthritis (OA) ranks fifth among all forms of disability affecting 10% of the world population. Current treatments available are associated with multiple side effects and do not slow down the progression of the disease. Moreover, no such effective treatment is available to date in various systems of medicine to treat osteoarthritis. Curcumin and Arnica have shown evident clinical advances in the treatment of osteoarthritis. Objective: The aim of the present study was to design, optimize and characterize novel herbal transdermal patches of curcumin and Arnica montana using fact

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21

Thi Soa, DANG, VU Thi Thuy, NGUYEN Duc Trung, et al. "LITERATURE REVIEW ON GLUCOSAMINE AND CHONDROITIN IN OSTEOARTHRITIS TREATMENT." Vinh University Journal of Science 53, no. 4A (2024): 59–69. https://doi.org/10.56824/vujs.2024a066a.

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Osteoarthritis is a chronic disease primarily characterized by articular cartilage damage. In Vietnam, osteoarthritis accounts for a high percentage of musculoskeletal conditions, especially affecting the knee joints. Recently, slow-acting anti- osteoarthritis drugs, including glucosamine, chondroitin sulfate, and diacerein, have been suggested as key pharmacological options for treating this condition. However, Vietnamese-language resources on these active ingredients remain limited. This article provides a literature review on the efficacy and safety of these drugs to enhance their effective

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22

Nasreen, Sulthana* Vijaya Kuchana Bindu Madhavi Bodupalli &. Ajay Godwin Potnuri. "EVALUATION OF IN-VITRO ANTI-ARTHRITIC AND ANTI-ANGIOGENIC ACTIVITY OF COMBINATION OF CURCUMIN AND DICLOFENAC SODIUM." Indian Journal of Medical Research and Pharmaceutical Sciences 5, no. 4 (2018): 27–33. https://doi.org/10.5281/zenodo.1214978.

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Osteoarthritis is a degenerative bone disorder characterized by cartilage destruction and bone remodelling. Multiple risk factors like age, sex, trauma, obesity and genetic predisposing factors are linked with osteoarthritis. Inflammation and angiogenesis are the main characteristic features of osteoarthritic pathophysiology. The present research was aimed to evaluate the <em>in vitro </em>anti-arthritic and anti angiogenic activity of curcumin, diclofenac sodium and their combination. Anti arthritic activity was evaluated by protein denaturation using bovine serum albumin. Denaturation was in

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23

Waraich, Harsimrat S., Vikas Kumar, Ashok Goel, and Jatinder Singh. "A comparative study to assess the safety and efficacy of etoricoxib versus aceclofenac in osteoarthritis." International Journal of Basic & Clinical Pharmacology 7, no. 10 (2018): 2010. http://dx.doi.org/10.18203/2319-2003.ijbcp20183939.

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Background: Osteoarthritis (OA) is most common form of arthritis; also referred as degenerative joint disease or “wear and tear” arthritis. Cyclooxygenase-2 (COX-2) inhibitors are effective for pain and inflammation in OA and gained importance over conventional non-steroidal anti-inflammatory agents (NSAIDs), as causes significantly less toxicity, particularly, in gastrointestinal tract. The objective of the present research was to study the short-term comparative clinical efficacy of aceclofenac and etoricoxib in patients with osteoarthritis and to compare the safety profile of the two drugs

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24

Cho, Soo-Kyung, Hyoungyoung Kim, Ha-Rim Park, et al. "Nonsteroidal Anti-inflammatory Drugs-sparing Effect of Symptomatic Slow-acting Drugs for Osteoarthritis in Knee Osteoarthritis Patients." Journal of Rheumatic Diseases 26, no. 3 (2019): 179. http://dx.doi.org/10.4078/jrd.2019.26.3.179.

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25

Gede Komang Aditya, I. "Duodenal Ulcer in Osteoarthritis Patient Using Non Steroidal Anti Inflammatory Drugs." International Journal of Science and Research (IJSR) 7, no. 7 (2018): 393–96. https://doi.org/10.21275/art20183856.

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26

Jennings, MB. "Comparison of piroxicam and naproxen in osteoarthritis of the foot." Journal of the American Podiatric Medical Association 84, no. 7 (1994): 348–54. http://dx.doi.org/10.7547/87507315-84-7-348.

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Osteoarthritis is the most common joint disease and the second highest ranking cause of disability in the US. Osteoarthritis commonly affects the hands, wrists, spine, knees, and feet. One of the mainstays of treatment for osteoarthritis is the use of nonsteroidal anti-inflammatory drugs. While there have been controlled comparison studies of the various nonsteroidal anti-inflammatory drugs, these have been limited to osteoarthritis of the hands, spine, and hip. This study was a randomized, double-blind, parallel study of 8 weeks' duration comparing piroxicam (Feldene, 20 mg daily) to naproxen

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27

Yu, Huan, Tianwen Huang, William Weijia Lu, Liping Tong, and Di Chen. "Osteoarthritis Pain." International Journal of Molecular Sciences 23, no. 9 (2022): 4642. http://dx.doi.org/10.3390/ijms23094642.

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Joint pain is the hallmark symptom of osteoarthritis (OA) and the main reason for patients to seek medical assistance. OA pain greatly contributes to functional limitations of joints and reduced quality of life. Although several pain-relieving medications are available for OA treatment, the current intervention strategy for OA pain cannot provide satisfactory pain relief, and the chronic use of the drugs for pain management is often associated with significant side effects and toxicities. These observations suggest that the mechanisms of OA-related pain remain undefined. The current review mai

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28

Alghamdi, Raed, Fabrizio Pertusati, and Polina Prokopovich. "Poly-beta-amino-ester licofelone conjugates development for osteoarthritis treatment." RSC Advances 14, no. 1 (2024): 15–28. http://dx.doi.org/10.1039/d3ra04967a.

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29

Singh, Poonam. "Integrated Management of Knee Osteoarthritis Associated Hypertension with Naturopathy and Yoga: A Case Report." International Research Journal of Ayurveda & Yoga 05, no. 10 (2022): 62–69. http://dx.doi.org/10.47223/irjay.2022.51009.

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Osteoarthritis of the Knees (OA Knees) also known as degenerative arthritis or degenerative joint disease is a group of mechanical abnormalities involving the degradation of joints, including articular cartilage and subchondral bone. Associated comorbid conditions such as hypertension increase the symptoms. Allopathic drugs taken to relieve the symptoms have their own side effects. The aim of treatment with naturopathy, yoga, and diet therapy is the reduction of symptoms and an increase in functional activities of patients with osteoarthritis of the knees. Naturopathy and therapeutic yogic exe

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30

Barthel, H. Richard, and Robert A. Axford-Gatley. "Topical Nonsteroidal Anti-Inflammatory Drugs for Osteoarthritis." Postgraduate Medicine 122, no. 6 (2010): 98–106. http://dx.doi.org/10.3810/pgm.2010.11.2227.

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31

BRANDT, KENNETH D., and SALLY SLOWMAN-KOVACS. "Nonsteroidal Antiinflammatory Drugs in Treatment of Osteoarthritis." Clinical Orthopaedics and Related Research &NA;, no. 213 (1986): 84???91. http://dx.doi.org/10.1097/00003086-198612000-00011.

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32

Hinz, Burkhard, and Kay Brune. "Pain and osteoarthritis: new drugs and mechanisms." Current Opinion in Rheumatology 16, no. 5 (2004): 628–33. http://dx.doi.org/10.1097/01.hco.0000136130.95746.14.

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33

JANCIN, BRUCE. "Osteoarthritis Drugs Offer Little Real Pain Relief." Family Practice News 36, no. 18 (2006): 47. http://dx.doi.org/10.1016/s0300-7073(06)73880-4.

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34

Wang, Kang, Jianhua Xu, David J. Hunter, and Changhai Ding. "Investigational drugs for the treatment of osteoarthritis." Expert Opinion on Investigational Drugs 24, no. 12 (2015): 1539–56. http://dx.doi.org/10.1517/13543784.2015.1091880.

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35

Zotkin, E. G., and S. Yu Shkireeva. "Adjuvant therapy of osteoarthritis with bioregulatory drugs." Modern Rheumatology Journal 19, no. 1 (2025): 98–104. https://doi.org/10.14412/1996-7012-2025-1-98-104.

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Osteoarthritis (OA) is a chronic progressive joint disease that ranks first in the frequency of all musculoskeletal diseases. OA is a serious general medical and social problem associated with a steady increase in prevalence. Reducing the pain in OA, maintaining active daily activity and preserving social functioning are the main goals of treatment for almost all patients suffering from this disease. In addition to the well-known traditional methods of treatment of OA, there are adjuvant therapies. Complex bioregulatory drugs are drugs whose composition is put together empirically and which co

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36

Lin, Jianjing, Shicheng Jia, Weifei Zhang, et al. "Recent Advances in Small Molecule Inhibitors for the Treatment of Osteoarthritis." Journal of Clinical Medicine 12, no. 5 (2023): 1986. http://dx.doi.org/10.3390/jcm12051986.

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Osteoarthritis refers to a degenerative disease with joint pain as the main symptom, and it is caused by various factors, including fibrosis, chapping, ulcers, and loss of articular cartilage. Traditional treatments can only delay the progression of osteoarthritis, and patients may need joint replacement eventually. As a class of organic compound molecules weighing less than 1000 daltons, small molecule inhibitors can target proteins as the main components of most drugs clinically. Small molecule inhibitors for osteoarthritis are under constant research. In this regard, by reviewing relevant m

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37

SS, Silpa, Aiswarya K, and Deepa M S. "An Ayurvedic treatment protocol on Temporomandibular Joint Osteoarthritis - A Case Report." Journal of Ayurveda and Integrated Medical Sciences 10, no. 4 (2025): 321–25. https://doi.org/10.21760/jaims.10.4.49.

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Temporomandibular Joint Osteoarthritis is a degenerative disorder affecting the temporomandibular joint, characterized by progressive cartilage degradation, subchondral bone changes, and inflammation. In Ayurveda, Temporomandibular Joint Osteoarthritis can be correlated with Hanusandhigata Vata. The disease has the symptoms like pain, joint noise, limited range of motion, impaired jaw function. This condition arises due to Asthikshaya in the Hanusandhi, here it is primarily caused by recurrent dislocation of the temporomandibular joint. Here an attempt is made on Temporomandibular joint osteoa

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38

Cao, Yifeng, Yifeng Ma, Yi Tao, Weifeng Lin, and Ping Wang. "Intra-Articular Drug Delivery for Osteoarthritis Treatment." Pharmaceutics 13, no. 12 (2021): 2166. http://dx.doi.org/10.3390/pharmaceutics13122166.

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Osteoarthritis (OA) is the most prevalent degenerative joint disease affecting millions of people worldwide. Currently, clinical nonsurgical treatments of OA are only limited to pain relief, anti-inflammation, and viscosupplementation. Developing disease-modifying OA drugs (DMOADs) is highly demanded for the efficient treatment of OA. As OA is a local disease, intra-articular (IA) injection directly delivers drugs to synovial joints, resulting in high-concentration drugs in the joint and reduced side effects, accompanied with traditional oral or topical administrations. However, the injected d

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39

Yu, Rong-Guo, Jia-Yu Zhang, Zhen-Tao Liu, et al. "Text Mining-Based Drug Discovery in Osteoarthritis." Journal of Healthcare Engineering 2021 (April 14, 2021): 1–14. http://dx.doi.org/10.1155/2021/6674744.

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Background. Osteoarthritis (OA) is a chronic and degenerative joint disease, which causes stiffness, pain, and decreased function. At the early stage of OA, nonsteroidal anti-inflammatory drugs (NSAIDs) are considered the first-line treatment. However, the efficacy and utility of available drug therapies are limited. We aim to use bioinformatics to identify potential genes and drugs associated with OA. Methods. The genes related to OA and NSAIDs therapy were determined by text mining. Then, the common genes were performed for GO, KEGG pathway analysis, and protein-protein interaction (PPI) net

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Jayprakash*, Kavita Lovanshi Shailesh Jain Rita Mourya Aashish Choudhory. "Drug Use Evaluation of Osteoarthritis." International Journal of Scientific Research and Technology 2, no. 5 (2025): 364–69. https://doi.org/10.5281/zenodo.15421698.

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Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by pain, stiffness, and functional impairment, leading to significant morbidity and healthcare burden. The management of OA often involves pharmacological interventions aimed at relieving symptoms and improving quality of life. However, the utilization patterns of drugs in OA management and their associated Adverse Drug Reactions (ADRs) remain areas of ongoing research and clinical interest. In this prospective study, we aimed to explore the drug utilization patterns and identify potential adverse drug reactions among

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Jayprakash*, Kavita Lovanshi Shailesh Jain Rita Mourya. "Drug Use Evaluation of Osteoarthritis." International Journal of Scientific Research and Technology 2, no. 5 (2025): 364–69. https://doi.org/10.5281/zenodo.15423445.

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Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by pain, stiffness, and functional impairment, leading to significant morbidity and healthcare burden. The management of OA often involves pharmacological interventions aimed at relieving symptoms and improving quality of life. However, the utilization patterns of drugs in OA management and their associated Adverse Drug Reactions (ADRs) remain areas of ongoing research and clinical interest. In this prospective study, we aimed to explore the drug utilization patterns and identify potential adverse drug reactions among

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42

K., Harsha Vardhan Rao S. Ijitha M. Sowmya Lavanya Yaidikar*. "CHARACTERIZATION OF PRESCRIBING PATTERN IN THE MANAGEMENT OF OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS IN A TERTIARY CARE HOSPITAL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 06 (2018): 5467–72. https://doi.org/10.5281/zenodo.1295598.

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Objectives: Osteoarthritis (OA), a progressive disorder characterized by destruction of articular cartilage with synovial changes. Rheumatoid arthritis (RA), a systemic inflammatory and autoimmune disease characterized by synovial inflammation, autoantibody production and joint space narrowing. Drugs like non-steroidal antiinflammatory drugs (NSAIDs), symptomatic slow acting drugs (SYSADOA) disease modifying anti-rheumatic drug (DMARDs), steroids etc are using widely in OA and RA therapy. A prescribing pattern study analyzes the trend of prescribing drugs, its rationality and provides feedback

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43

Jnyah, MK, I. El Mezouar, N. Akasbi, and T. Harzy. "Is Hypovitaminosis D Associated with Increased Pain in Patients with Knee Osteoarthritis?" SAS Journal of Medicine 10, no. 07 (2024): 612–16. http://dx.doi.org/10.36347/sasjm.2024.v10i07.005.

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Objective: Osteoarthritis is considered the most frequent joint pathology mostly interesting the knee. Hypovitaminosis D, frequent during postmenopausal period, is usually found during osteoarthritis. The aim of this study was to investigate a possible association between hypovitaminosis D in patients followed for knee osteoartritis and an increase in pain. Material and Methods: This is a retrospective descriptive and analytical study including 228 patients followed up for knee osteoarthritis in rheumatology consultation between January 2021 and February 2023. Patients who received vitamin D s

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44

Nosivets, D. S. "A Study of Serum Bone Alkaline Phosphatase Levels in Rats with Experimental Equivalents of Hypothyroidism and Osteoarthritis on the Background of NSAIDS and Paracetamol Administration." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6, no. 1 (2021): 32–36. http://dx.doi.org/10.26693/jmbs06.01.032.

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The article investigated changes in the level of bone alkaline phosphatase under the influence of non-steroidal anti-inflammatory drugs and paracetamol under experimental equivalents of hypothyroidism and osteoarthritis. There is a clear need to identify biomarkers that could predict a patient's response to osteoarthritis treatment, primarily in comorbid conditions. It is known that hypofunction of the thyroid gland leads to metabolic disorders that negatively affect the condition of bone and cartilage, causing the development of osteoarthritis. One manifestation of osteoarthritis is considere

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45

Nosivets, D. S. "Influence of Non-steroidal Anti-Inflammatory Drugs and Paracetamol on the Level of C-Reactive Protein of Rat Blood Serum in Experimental Equivalents of Hypothyroidism and Osteoarthritis." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5, no. 6 (2020): 79–83. http://dx.doi.org/10.26693/jmbs05.06.079.

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The article investigated changes in the level of C-reactive protein under the influence of non-steroidal anti-inflammatory drugs and paracetamol under experimental equivalents of hypothyroidism and osteoarthritis. There is a clear need to identify biomarkers that could predict a patient's response to osteoarthritis treatment, primarily in comorbid conditions. It is known that hypofunction of the thyroid gland leads to metabolic disorders that negatively affect the condition of bone and cartilage, causing the development of osteoarthritis. One manifestation of osteoarthritis is considered to be

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Knezevic, Aleksandar, Larisa Vojnovic, Dunja Popovic, Tijana Spasojevic, and Enis Garipi. "Knee osteoarthritis treatment." Medical review 75, Suppl. 2 (2022): 57–61. http://dx.doi.org/10.2298/mpns22s2057k.

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Introduction. Osteoarthritis is the most common form of arthritis which affects millions of people worldwide and represents the leading cause of disability among the elderly. There is a substantial number of guidelines available for the treatment of knee osteoarthritis. The primary aim of this paper is to explore the distinctions and similarities between knee osteoarthritis treatment guidelines. The treatment is divided into core treatment and additional steps. Core treatment of knee osteoarthritis involves education of the patient, weight loss in the case of overweight patients and establishi

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Svetlova, M. S. "Efficacy of Theraflex Chondrocream Forte in the combination treatment of knee osteoarthritis." Medical Council, no. 9 (June 12, 2019): 81–84. http://dx.doi.org/10.21518/2079-701x-2019-9-81-84.

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The problem of osteoarthritis treatment appears especially relevant today due to high prevalence of the disease and unsafety of drugs used by patients to relieve pain. Knee joints are affected most often. The chronic pain and joint functional disorder worsen dramatically the patients’ quality of life and result in destabilization of coexisting diseases. Topical drugs are commonly used in the combination treatment of osteoarthritis. The article presents research results of efficacy of Theraflex Chondrocream Forte in the combination treatment of knee lesions. The use of the drug results in a mor

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Badokin, V. V., and V. V. Badokin. "THE CORES A SYMPTOM-MODIFYING PREPARATIONS OF THE SLOWEDDOWN ACTION IN THERAPY OF OSTEOARTROSIS." Osteoporosis and Bone Diseases 13, no. 1 (2010): 28–33. http://dx.doi.org/10.14341/osteo2010128-33.

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Osteoarthritis is the most common disorders of the locomotor system. This is multifaktor disorder and the inflammation in the bones and cartilage, synovial envelope and subhondral bone play the important role in the pathogenesis of osteoarthritis. The main symptom-modified drugs are glikozamin sulfate and chondroitine sulfate, which have a high degree of evidence. These agents not only suppress pain and normalize function affected joints but also slowed progression of osteoarthritis, normalize and stabilize the structural changes in gyaline cartilage, warn changes in noninvolved joint. Therafl

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Chichasova, N. V., G. R. Imametdinova, and A. M. Lila. "Safe therapy of osteoarthritis: place of topical nonsteroidal anti-inflammatory drugs." Meditsinskiy sovet = Medical Council, no. 8 (July 16, 2020): 128–34. http://dx.doi.org/10.21518/2079-701x-2020-8-128-134.

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The article discusses the social significance of osteoarthritis as a widespread disease that develops mainly in older people, which makes it difficult to carry out anti-inflammatory and analgesic therapy due to the frequent combination of osteoarthritis with other diseases at this age, the need to treat comorbid conditions, which is often poorly combined with systemic therapy with non-steroidal anti-inflammatory drugs. It is noted that osteoarthritis not only worsens the quality of life of patients, but also leads to a decrease in the length of their life, which emphasizes the medical and soci

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Daniela, Neagu, Leblond Clarisse, Biriș Alexandra, Codea Răzvan, Popovici Cristian, and Mureșan Alexandra. "The management of arthritic pain in dogs– a review." Scientific Papers Journal VETERINARY SERIES 66, no. 4 (2023): 137–46. http://dx.doi.org/10.61900/spjvs.2023.04.23.

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Osteoarthritis is a common condition in dogs, particularly affecting elderly individuals, and the chronic pain it causes significantly impacts the quality of life of affected dogs. First, we will focus on the joint, the physiopathology of osteoarthritis, and the mechanisms of arthritic pain production, and then discuss the existing treatments. There are numerous treatments available for managing this complex osteoarticular condition, but unconventional therapies are increasingly of interest to owners of canine species. Phytotherapy harnesses the healing properties of plants for treatment in a

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