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Journal articles on the topic 'Osteolytic bone lesion'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Park, Kwang Hwan, Yeokwon Yoon, Jae Han Park, Seung Hwan Han, and Jin Woo Lee. "Outcomes of Bone Graft for Periprosthetic Osteolysis after Total Ankle Arthroplasty." Foot & Ankle Orthopaedics 7, no. 4 (2022): 2473011421S0087. http://dx.doi.org/10.1177/2473011421s00873.

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Category: Ankle Arthritis Introduction/Purpose: Periprosthetic osteolysis after total ankle arthroplasty (TAA) is a substantial problem. It has potential to affect implant survival. To prevent implant failure, it is important to decide an appropriate timing of surgical intervention such as bone graft. We report our outcomes of bone graft for osteolysis after TAA. Methods: We retrospectively evaluated our consecutive series of 470 primary TAAs performed between May 2004 and August 2019 and identified those who received operative management for periprosthetic osteolysis. A total of 43 bone graft

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Sung, S., S. Lim, H. Oh, K. Kim, Y. Choi, and K. Lee. "Atypical radiographic features of multiple myeloma in a dog: a case report." Veterinární Medicína 62, No. 9 (2017): 522–26. http://dx.doi.org/10.17221/140/2016-vetmed.

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A 12-year-old castrated male miniature pinscher dog presented with right forelimb lameness. An expansile osteolytic lesion of the right humerus was conspicuous on right forelimb radiographs. Thoracic and abdominal radiographs showed multiple lytic bone lesions on the right scapula, ribs, vertebrae, femurs and pelvis. Additionally, an expansile osteolytic lesion was observed in two thoracic vertebrae and two ribs. Many plasma cells were identified on fine-needle aspiration of the right humerus expansile osteolytic lesion, and monoclonal gammopathy consistent with multiple myeloma was confirmed

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Battikh, Naim G., Elrazi Awadelkarim Awadelkarim Hamid Ali, and Mohamed A. Yassin. "Osteolytic Bone Lesions in Patients with Primary Myelofibrosis: A Systematic Review." Blood 138, Supplement 1 (2021): 4624. http://dx.doi.org/10.1182/blood-2021-144449.

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Abstract Background: Philadelphia negative Myeloproliferative neoplasms classically characterized by excess production of terminal myeloid cells in the peripheral blood. Among this group, primary myelofibrosis is the least common and usually carries the worst prognosis. Bone involvement in primary myelofibrosis has many forms and tend to manifest as osteosclerotic lesions in vast majority of cases, however osteolytic lesions are reported in exceptional occasions. In this review, we tried to shed the light on this rare association. Methods: We performed a systematic review following the Preferr

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Xiong, Wei, Neil Yeung, Shubo Wang, Haofu Liao, Liyun Wang, and Jiebo Luo. "Breast Cancer Induced Bone Osteolysis Prediction Using Temporal Variational Autoencoders." BME Frontiers 2022 (April 7, 2022): 1–10. http://dx.doi.org/10.34133/2022/9763284.

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Objective and Impact Statement. We adopt a deep learning model for bone osteolysis prediction on computed tomography (CT) images of murine breast cancer bone metastases. Given the bone CT scans at previous time steps, the model incorporates the bone-cancer interactions learned from the sequential images and generates future CT images. Its ability of predicting the development of bone lesions in cancer-invading bones can assist in assessing the risk of impending fractures and choosing proper treatments in breast cancer bone metastasis. Introduction. Breast cancer often metastasizes to bone, cau

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Murphy, Ryan J., Michael D. M. Kutzer, Sean M. Segreti, Blake C. Lucas, and Mehran Armand. "Design and kinematic characterization of a surgical manipulator with a focus on treating osteolysis." Robotica 32, no. 6 (2013): 835–50. http://dx.doi.org/10.1017/s0263574713001082.

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SUMMARYThis paper presents a cable-driven dexterous manipulator with a large, open lumen. One specific application for the manipulator is the treatment of the degeneration of bone tissue (osteolysis) during a less-invasive hip revision surgery. Rigid tools used in traditional approaches limit the surgeons' ability to comprehensively treat the osteolysis due to the complex geometries of the lesion. The surgical scenario, testing, kinematic modeling, and image-based inverse kinematics are described. Testing shows 94% coverage of a lesion wall; the kinematic model describes manipulator notch posi

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Hornig, Gregory W., and Robert M. Beatty. "Osteolytic skull lesions secondary to trauma." Journal of Neurosurgery 72, no. 3 (1990): 506–8. http://dx.doi.org/10.3171/jns.1990.72.3.0506.

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✓ Two patients with posttraumatic osteolytic skull lesions are presented and discussed. One was operated on, and pathological examination confirmed an inflammatory reactive process within the bone lesion.

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Hansen, Jeanette Ansholm, Mohammad Naghavi-Behzad, Oke Gerke, et al. "Diagnosis of bone metastases in breast cancer: Lesion-based sensitivity of dual-time-point FDG-PET/CT compared to low-dose CT and bone scintigraphy." PLOS ONE 16, no. 11 (2021): e0260066. http://dx.doi.org/10.1371/journal.pone.0260066.

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We compared lesion-based sensitivity of dual-time-point FDG-PET/CT, bone scintigraphy (BS), and low-dose CT (LDCT) for detection of various types of bone metastases in patients with metastatic breast cancer. Prospectively, we included 18 patients with recurrent breast cancer who underwent dual-time-point FDG-PET/CT with LDCT and BS within a median time interval of three days. A total of 488 bone lesions were detected on any of the modalities and were categorized by the LDCT into osteolytic, osteosclerotic, mixed morphologic, and CT-negative lesions. Lesion-based sensitivity was 98.2% (95.4–99.

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Pakos, Emilios E., Dimitrios N. Gartzonikas, Pericles G. Tsekeris, and Theodore A. Xenakis. "Solitary Tibial Osteolytic Lesion." Case Reports in Medicine 2009 (2009): 1–3. http://dx.doi.org/10.1155/2009/352085.

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We report an unusual case of solitary osteolytic tibial metastasis from a primary endometrial cancer in a 62-year-old woman. The primary cancer was treated with total abdominal hysterectomy and bilateral salpingo-oophorectomy combined with postoperative external beam radiotherapy, while the tibial metastasis was treated with an above knee amputation. The rarity of the case lies on the fact that metastases distally to the elbow and knee are uncommon and endometrial cancer rarely gives distal bone metastases and particularly solitary to the extremities.

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Ganguly, Sourik, Paul Daft, Jingchen Cao та ін. "Loss of Myeloid-Specific TGF-β Signaling Decreases CTHRC1 to Downregulate bFGF and the Development of H1993-Induced Osteolytic Bone Lesions". Cancers 10, № 12 (2018): 463. http://dx.doi.org/10.3390/cancers10120463.

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The role of myeloid cell-specific TGF-β signaling in non-small-cell lung cancer (NSCLC)-induced osteolytic bone lesion development is unknown. We used a genetically engineered mouse model, Tgfbr2LysMCre knockout (KO), which has a loss of TGF-β signaling specifically in myeloid lineage cells, and we found that the area of H1993 cell-induced osteolytic bone lesions was decreased in Tgfbr2LysMCre KO mice, relative to the area in control littermates. The bone lesion areas were correlated with tumor cell proliferation, angiogenesis, and osteoclastogenesis in the microenvironment. The smaller bone l

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Zhang, Ying, Chunlei Zhao, Hongbiao Liu, Haifeng Hou, and Hong Zhang. "Multiple Metastasis-Like Bone Lesions in Scintigraphic Imaging." Journal of Biomedicine and Biotechnology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/957364.

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Multiple benign osteolytic lesions are very hard to differentiate from disseminated bone metastasis. Whole-body bone scintigraphy (WBBS) with technetium-99m methylene diphosphonate (Tc-99m MDP) demonstrates multiple lesions with increased uptake in any bone involved. Even combined with medical history and multiple imaging results, such as MRI and CT, the clinical diagnosis of metastasis lesion remains as a challenge. These clinical characteristics are similar to multiple malignant bone metastases and therefore affect the following treatment procedures. In this paper, we analyzed multiple benig

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Sobota, Jana Kerstin Betty, Hanna Kienapfel, Mathias Werner, and Dominik Maximilian Vogt. "Intraosseous myolipoma of the calcaneus." BMJ Case Reports 17, no. 3 (2024): e259743. http://dx.doi.org/10.1136/bcr-2024-259743.

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A man in his 40s presented with an incidental finding of an osteolytic bone lesion. He sustained an ankle injury while inline skating, fracturing his lateral malleolus. Besides the fracture, radiographic imaging on the day of the injury incidentally revealed a well-defined solitary osteolytic lesion with a sclerotic rim within the right calcaneus. MRI showed an intraosseous, fat-containing lesion with focal contrast enhancement, assessed as an intraosseous lipoma with central necrosis. In the pathological analysis of a sample of the lesion an intraosseousmyolipoma of the calcaneus was found—an

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N., Geetha, Sreelesh KP, Priya Mary Jacob, Lali VS, and Rekha A. Nair. "Osteolytic bone lesions – A rare presentation of AML M6." Mediterranean Journal of Hematology and Infectious Diseases 7 (February 12, 2015): e2015017. http://dx.doi.org/10.4084/mjhid.2015.017.

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Acute myeloid leukemia (AML) M6 is a rare form of AML accounting for < 5 % of all AML. Extramedullary involvement is very rarely seen in this entity. Skeletal lesion has not been described in AML M6 before. We discuss the case of a 17 year old boy with AML M6 who presented with osteolytic lesion of right humerus. He was treated with induction and consolidation chemotherapy. The present case is the first report in literature of AML M6 presenting with skeletal lesions.

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Memiş, Kemal Buğra, and Esra Bilici. "Bizarre Parosteal Osteochondromatous Proliferation of the Humerus with Radiological Findings: A Case Report." Advanced Radiology and Imaging 1, no. 1 (2024): 17–19. https://doi.org/10.4274/AdvRadiolImaging.galenos.2024.87597.

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AbstractBizarre parosteal osteochondromatous proliferation (BPOP) is a rare, benign bone disease that primarily affects the metacarpals and metatarsals. We describea 17-year-old male teenager with proximal humeral BPOP. It is a trabeculated osteolytic lesion on radiological examination. An excisional biopsy confirmedthe diagnosis. Very few cases of BPOP in the long bones have been documented. It is an extension that emerges from the bone’s cortical surface and isexophytic. Because the lesion was discovered in a rare location-the proximal diaphysis of the case is being reported. The gold

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Clarençon, Frédéric, Eimad Shotar, Evelyne Cormier, et al. "Transoral vertebroplasty for the C1 lateral mass." Journal of NeuroInterventional Surgery 12, no. 9 (2020): 879–85. http://dx.doi.org/10.1136/neurintsurg-2020-015853.

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BackgroundOsteolytic lesions of the atlas (C1) are challenging to treat by vertebroplasty due to the vicinity of the vertebral artery and the spinal cord.ObjectiveTo present our experience with transoral vertebroplasty (TOV) for osteolytic lesions of the lateral mass of the atlas.MethodsRetrospective case series involving 15 consecutive patients (nine male, six female, mean age 63 years) who underwent TOV for the treatment of an osteolytic lesion of the lateral mass of the atlas. Among the osteolytic lesions, 10/15 (67%) were bone metastases from various cancers; 4/15 (27%) were lesions relate

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Grunz, Jan-Peter, Andreas Steven Kunz, Freerk T. Baumann, et al. "Assessing Osteolytic Lesion Size on Sequential CT Scans Is a Reliable Study Endpoint for Bone Remineralization in Newly Diagnosed Multiple Myeloma." Cancers 15, no. 15 (2023): 4008. http://dx.doi.org/10.3390/cancers15154008.

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Multiple myeloma (MM) frequently induces persisting osteolytic manifestations despite hematologic treatment response. This study aimed to establish a biometrically valid study endpoint for bone remineralization through quantitative and qualitative analyses in sequential CT scans. Twenty patients (seven women, 58 ± 8 years) with newly diagnosed MM received standardized induction therapy comprising the anti-SLAMF7 antibody elotuzumab, carfilzomib, lenalidomide, and dexamethasone (E-KRd). All patients underwent whole-body low-dose CT scans before and after six cycles of E-KRd. Two radiologists in

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Khan, Eshita Reza, Chowdhury Yakub Jamal, Anwarul Karim, Ismat Nigar, and Farah Diba. "A Child with Chronic Fungal Infection in Bangladesh that Mimicked Malignancy: Disseminated Histoplasmosis." Bangladesh Journal of Child Health 42, no. 2 (2018): 94–97. http://dx.doi.org/10.3329/bjch.v42i2.37765.

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Histoplasma capsulatum is a dimorphic fungus, which primarily causes a pulmonary disease. It is found throughout the world with the soil being the environmental reservoir. In infants and toddlers, disseminated histoplasmosis is the commonest presentation. In this age group, 60-80% patients has acute disseminated progressive disease. Disseminated histoplasmosis may also cause bone involvement with osteolytic lesion. Here, we have described a rare and unusual disseminated histoplasmosis, a 3 and half year old boy from Bangladesh with multiple abscess like soft tissue lesions, along with multiple

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Eckardt, André M., Klaus Reichstein, and M. Heine. "Interdisciplinary Surgical Management of Simultaneous Bone Metastases in Uterine Cervix Carcinoma: Total Replacement of Temporomandibular Joint and Stabilization of the Cervical Spine." Craniomaxillofacial Trauma & Reconstruction Open 5 (January 1, 2020): 247275122095008. http://dx.doi.org/10.1177/2472751220950083.

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Metastasis to the mandibular condyle and cervical spine in oncologic patients is rare, and clinicians should therefore be alert if patients present with such suspicious lesions for further clinical and pathological examinations. A 58-year old female patient with uterine cervical cancer initially presented with mild left condylar dysfunction. CT-imaging revealed a progressive osteolytic lesion of the left condyle and at the same time CT-scans revealed an osteolytic lesion of the cervical spine. Further metastatic bone lesions were ruled out. An incisional biopsy of the left condyle revealed met

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Torres Ríos, Jorge Alejandro, Mauricio Muleiro Álvarez, Javier Iván Armenta Moreno, Felipe Esparza Salazar, Alejandro Rodríguez Camacho, and Ramiro Cabrera Carranco. "Gorham-Stout syndrome with cervical involvement treated with radiotherapy: a case report." Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare 3, no. 6 (2023): 39–44. http://dx.doi.org/10.36105/psrua.2023v3n6.04.

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Gorham-Stout disease (GSD), vanishing bone or phantom bone disease, is an uncommon disease whose etiology is uncertain and its pathophysiology poorly understood. This syndrome is characterized by the spontaneous destruction of the bone matrix associated with massive osteolysis and proliferation of lymphatic vascular structures in the affected areas. In the present article we present a case of GSD in a 10-year-old male patient with osteolytic lesions affecting the skull base, including the occipital bone, the petrous portion of the temporalis and clivus, as well as the vertebral bodies from C1

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Bucelli, Cristina, Daniele Cattaneo, Viviana Beatrice Valli, et al. "Osteolytic Lesions in Primary Myelofibrosis and Effect of Ruxolitinib Therapy: Report of a Case and Literature Review." Chemotherapy 63, no. 6 (2018): 340–44. http://dx.doi.org/10.1159/000497246.

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Here, we report the case of a young female affected by primary myelofibrosis (PMF) who developed an osteolytic lesion of the humerus during the follow-up, and the possible efficacy of ruxolitinib in controlling this rare event. After 26 years of follow-up, the patient reported onset of acute pain at the proximal region of the left upper limb. An X-ray revealed an osteolytic bone lesion in the proximal third of the humeral shaft, which was then confirmed by magnetic resonance imaging. A biopsy of the lytic lesion was done, revealing hypercellular bone marrow with hyperplastic granulopoiesis ass

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Marinescu, A. N., A. I. Nicula, and G. Iana. "A Tool in Differential Diagnosis of a “Cystic” Bone Lesion." Romanian Journal of Orthopaedic Surgery and Traumatology 1, Supplement (2018): 32. http://dx.doi.org/10.2478/rojost-2018-0043.

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Abstract It is a power point program, which through a succession of steps, allows the obtaining of one shorter diagnosis, from a long list of possible ones, by choosing a character of the bone lesion. The aim of this program is to facilitate the differential diagnosis of this particular aspect of a bone lesion - the cystic, expansile osteolytic bone lesion - from a radiological point of view, but not only. The location, age, pain and other condition will be considered and will represent the first criteria in the differentiation. In this differential diagnosis, we discovered not only benign tum

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attia, amro. "role of endoscopy in osteolytic bone lesion management." Al-Azhar International Medical Journal 2, no. 5 (2021): 25–30. http://dx.doi.org/10.21608/aimj.2021.72157.1457.

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Jung, Sung-Hoon, Jae-Sook Ahn, Deok-Hwan Yang, Yeo-Kyeoung Kim, Hyeoung-Joon Kim, and Je-Jung Lee. "Effect Of Advanced Lytic Bone Lesions On Peripheral Stem Cell Mobilization In Patients With Multiple Myeloma." Blood 122, no. 21 (2013): 3276. http://dx.doi.org/10.1182/blood.v122.21.3276.3276.

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Abstract The purpose of this study was to identify incidence and predictive factors of peripheral blood stem cell (PBSC) mobilization failure in patients with multiple myeloma (MM). Retrospective data of 104 patients who received cyclophosphamide plus G-CSF or G-CSF alone mobilization were analyzed. The rate of mobilization failure using two definitions of failure < 2 and < 4 ´ 106 CD34+ cells/kg following the first collection attempt was 16.3% and 33.7%, respectively. Predictors of mobilization failure were evaluated using logistic regression analysis including age, advanced osteolytic

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Prasetyo, Nora A., Budi Darmawan, Erwin Affandi, and A. Hussein S. Kartamihardja. "The Role of Bone Scintigraphy and Parathyroid Scintigraphy on Multiple Osteolytic Lesions Which Misdiagnosed as Primary Bone Tumor (Giant Cell Tumor)." Medicinus 10, no. 1 (2023): 42. http://dx.doi.org/10.19166/med.v10i1.6993.

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<p>Brown tumor is a non-neoplastic lesion that resulting from abnormal bone metabolism. It can be manifest in prolonged or untreated hyperparathyroidism. The clinical symptoms, radiological and histopathological examination were similar with giant cell tumor and can be mimicking metastases; or even misdiagnosed with giant cell tumor and mistreated the patient. Biochemical examination of calcium levels and parathyroid hormone should be included in the routine assessment of patients with multiple osteolytic lesions. A multidiscipline approach is needed.Throughout this case report, we would

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Shrestha, Amin Kumar, Suman Raja Shrestha, Gopesh Kumar Thakur, and Arjun Prasad Dumre. "Tubercular Osteomyelitis of Tibia: A Case Report." Nepal Medical Journal 2, no. 1 (2019): 92–94. http://dx.doi.org/10.37080/nmj.27.

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Tubercular osteomyelitis of long bone is extremely rare and very few cases have been reported in literature. We are presenting a case of 43 years gentlemen presented with pain and swelling over lower half of leg for 5 months. There was associated pus discharging sinus and often low-grade fever but no history of weight loss or pulmonary symptoms. X-ray chest was normal. X-rays of involved leg was suggestive of osteomyelitis. Curettage and Biopsy was done, report was suggestive of tuberculous osteomyelitis. As tuberculosis is still common in developing countries like Nepal, for any osteolytic le

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Lawal, Ismaheel O., Mehmet A. Bilen, Raghuveer K. Halkar, Ashesh B. Jani, and David M. Schuster. "Prostate Cancer Skeletal Metastasis: A Spontaneous Evolution from Osteolytic to Osteoblastic Morphology without Treatment." World Journal of Nuclear Medicine 22, no. 04 (2023): 316–20. http://dx.doi.org/10.1055/s-0043-1777697.

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AbstractSkeletal metastases due to prostate cancer (PCa) are more commonly osteoblastic than osteolytic. In the rarer cases of osteolytic skeletal metastasis of PCa, transition to osteoblastic phenotype occurs following treatment, which indicates successful healing. In this report, we present a case of spontaneous osteolytic to osteoblastic evolution of PCa skeletal metastasis without treatment in a patient with recurrence of PCa. Our patient is a 59-year-old male who had a robotic radical prostatectomy in July 2014 for a T2c adenocarcinoma of the prostate gland (Gleason score = 4 + 3). He had

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Rahman, Syed Hifzur, Smruti Srinivasan, Abhishek Kumar Rai, K. G. Geekesh Kumar, Amey Santosh Sadar, and Sushant Sudhir Srivastava. "Rare Case of Gaucher’s Disease Presenting as a Solitary Swelling of the Proximal Tibia Mimicking a Musculoskeletal Tumor in an Adult: A Case Report." Journal of Orthopaedic Case Reports 12, no. 3 (2022): 64–67. http://dx.doi.org/10.13107/jocr.2022.v12.i03.2720.

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Introduction: Gaucher’s disease is a congenital lysosomal storage disorder caused by an autosomal recessive mutation in B-glucocerebrosidase. It is a multi-system disease, wherein patients present with hematological abnormalities, joint pain, osteonecrosis, and developmental delay. We present a case of 38-year-old male with a painless solitary soft-tissue swelling over the left proximal tibia, eventually diagnosed it to be a case of Gaucher’s disease. This case is unique in the literature, because this subcutaneous Gaucher mass was not associated with a significant past history and was being e

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Bano, Safia, Zomer Sardar, Muhammad Kalim, and Ahsan Numan. "Osteolytic Skull Lesions: Rare Finding in a Patient Presenting with Clinical Features of Progressive Multifocal Leukoencephalopathy (PML) With Unknown HIV Status." Annals of King Edward Medical University 28, no. 1 (2022): 123–27. http://dx.doi.org/10.21649/akemu.v28i1.5021.

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Bacillary angiomatosis (BA) is a rare but an infrequent opportunistic infection reported mostly in HIV-infected patients. The most common site of involvement is the skin manifestation followed by solid organs involvement like liver and bone. Although most cutaneous manifestations are treatable, the other organs involvement can be fatal in some cases. We report a case of an isolated osteolytic lesion due to the Bacillary angiomatosis (BA). We conclude that Bacillary angiomatosis (BA) should be suspected and screened when an osteolytic bone lesion is identified in immunocompromised patients like

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Peric, Predrag, Branislav Antic, and Olga Radic-Tasic. "Aneurysmal bone cyst of the frontal bone." Vojnosanitetski pregled 62, no. 6 (2005): 491–94. http://dx.doi.org/10.2298/vsp0506491p.

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Background. Aneurysmal bone cyst (ABC) is a benign, expansive, osteolytic lesion that mainly occurs in young people, and involves the skull bones only exceptionally. The origin of ABC is controversial: secondary reactive bone lesion, or primary disease that represents an independent nosological entity. Blunt head trauma was suggested as a possible etiological factor. Case report. A case of a 19-year old man with primary ABC of the right frontal bone was reported. The lesion was totally excised through frontal craniotomy, and the skull bone defect primarily reconstructed with an acrilate cranio

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Tandra, Varun Sharma, Krishna Mohan Reddy Kotha, Moorthy Gadisetti Venkata Satyanarayana, Kali Varaprasad Vadlamani, and Vyjayanthi Yerravalli. "Synchronous Multicentric Giant Cell Tumour of Distal Radius and Sacrum with Pulmonary Metastases." Case Reports in Oncological Medicine 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/354158.

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Giant cell tumour (GCT) is an uncommon primary bone tumour, and its multicentric presentation is exceedingly rare. We report a case of a 45-year-old female who presented to us with GCT of left distal radius. On the skeletal survey, osteolytic lesion was noted in her right sacral ala. Biopsy confirmed both lesions as GCT. Pulmonary metastasis was also present. Resection-reconstruction arthroplasty for distal radius and thorough curettage and bone grafting of the sacral lesion were done. Multicentric GCT involving distal radius and sacrum with primary sacral involvement is not reported so far to

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Wirotama, Androcles Dwi, Steven Tandean, and Celine Augla D’Prinzessin. "Osteolytic lesion in primary intracranial meningioma: A case report." Intisari Sains Medis 15, no. 1 (2024): 22–24. http://dx.doi.org/10.15562/ism.v15i1.1941.

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Background: Hyperostosis of the skull is one of the characteristics of intracranial meningioma. In contrast, osteolytic lesions are very rarely discovered in meningioma. This study presented a rare instance of intracranial meningioma accompanied by significant osteolytic lesions. Case presentation: A 70-year-old male patient presented with a chief complaint of a left-sided scalp lump which developed progressively within two years. Seizures and right-sided weakness have been reported. A mass of approximately 8 cm in diameter with a smooth surface was noted during a physical examination. The bra

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Tamaki, Tatsuya, and Kazuhiro Oinuma. "Natural Remission of Major Periprosthetic Osteolysis following Total Hip Arthroplasty with Metal-on-Metal Bearings." Case Reports in Orthopedics 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/2576196.

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The natural course of adverse events following the use of metal-on-metal (MoM) bearings in total hip arthroplasty (THA) is not well known. In this article, we report the case of a patient with asymptomatic major acetabular osteolysis following MoM THA that diminished gradually without any surgical intervention. A 58-year-old male underwent one-stage bilateral MoM THA for bilateral osteoarthritis. Four years after THA, major acetabular osteolysis developed in his right hip without any local or systemic symptoms. The patient underwent a careful radiographic and clinical observation without any s

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Lemos, Samuel Sequeira, Diogo Belo, and Filipe Veloso Gomes. "Giant sacral aneurysmal bone cyst treated with endovascular embolization." Surgical Neurology International 14 (October 20, 2023): 373. http://dx.doi.org/10.25259/sni_685_2023.

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Background: Spine aneurysmal bone cysts (SABC) are osteolytic tumor-like lesions with cystic, blood-filled cavities that represent 15% of all primary spinal bone tumors. The sacrum is a rare site for SABC, and sacral lesions typically carry higher morbidity rates. Here, a 19-year-old female with a large primary multisegmental sacral SABC was successfully managed with 2-staged endovascular embolization. Case Description: A 19-year-old female presented with progressive worsening of axial lumbosacral pain, and a left L5/S1 radiculopathy. The lumbosacral computed tomography and magnetic resonance

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Mohammadi, Afshin, Abbas Hedayati Asl, Mohammad Ghasemi-Rad, and Farahnaz Noroozinia. "Enchondroma Protuberans of Ulnar Bone: A Case Report and Review of Literature." Case Reports in Radiology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/278920.

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Introduction. Enchondroma protuberans is an extremely rare benign cartilaginous bone tumor. We report the first case report of enchondroma protuberans in the forearm.Presentation of Case. We report a case of enchondroma protuberans originating in the left ulnar bone of a young woman. A 20-year-old female referred to our hospital complaining of progressive sustained left forearm pain with a radiation to fourth and fifth finger. Conventional radiography revealed a well-defined eccentric osteolytic lesion in the distal diaphysis of ulna with expansion of overlying cortex (without calcification).

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Shamala, S., A. Beeula, M. Devi, and P. Hariganesh. "A large aneurysmal bone cyst of mandible: A rare case report." Journal of Oral and Maxillofacial Pathology 27, no. 3 (2023): 548–52. http://dx.doi.org/10.4103/jomfp.jomfp_459_22.

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An aneurysmal bone cyst (ABC) is a rare benign tumor-like lesion, described as an expanding osteolytic lesion consisting of blood-filled spaces of variable sizes separated by connective tissue septa. It is frequently accompanied by multiple cystic lesions due to aggressive hemodynamics with reactive bone formation and a genetic predisposition. This lesion has been classified as an atypical giant cell tumor or benign bone cyst. ABC has an incidence of 0.5% and comprises approximately around 1.5% of all non-odontogenic and non-epithelial cysts of the jaws. About 50% of the ABCs are reported in l

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Senapati, Satya Bhusan, Sudhansu Sekhar Mishra, Manmath Kumar Dhir, Srikanta Das, and Kalpalata Tripathy. "A case of multiple myeloma presenting as scalp swelling with intracranial extension." Journal of Neurosciences in Rural Practice 04, no. 04 (2013): 445–48. http://dx.doi.org/10.4103/0976-3147.120230.

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ABSTRACTMultiple myeloma is a malignant neoplasm of bone marrow affecting plasma cells. It is usually detected in skull bone with characteristic features of multiple punched-out lesions. Its presentation as a solitary scalp swelling with underlying skull bone erosion and intracranial extension is very rare. A 35-year-old female presented to us with complains of rapidly growing left-side scalp swelling with right-side paresis and simple partial seizure of right upper limb. Local examination, X-ray skull, CT scan, and MRI of brain were suggestive of a malignant lesion. Near total excision of les

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Arshdeep, K. R., B. G. Subhas, S. Shetty, and C. Mishra. "Multiple myeloma with primary manifestation in the mandible: a case report." Nigerian Dental Journal 18, no. 2 (2010): 80–82. http://dx.doi.org/10.61172/ndj.v18i2.148.

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Plasma cell neoplasms (multiple myeloma, solitary plasmocytoma of bone and extra medullar plasmocytoma) are characterized by a monoclonal neoplastic proliferation of plasma cells. Multiple myeloma is a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions in the vertebrae, ribs, pelvic bone, skull and jaw. We report a case of a 69-year-old male patient who presented with a tumefaction in the body of mandible, which had evolved over the previous two months. In the radiographic examination, an extensive osteolytic lesion was observed in the body of mandible. An incisi

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Hossain, Mohana, Hosne Ara Rahman, Mahbubul Haque, et al. "Radionuclide Bone Scintigraphy: An Interesting Case Report." Bangladesh Journal of Nuclear Medicine 17, no. 1 (2015): 111–15. http://dx.doi.org/10.3329/bjnm.v17i1.22502.

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It is well established that Technetium99mmethylene diphosphonate (Tc99m MDP) whole body bone scintigraphy (WBBS) can demonstrate multiple lesions with increased radiotracer concentration in involved bone. But it is hard to differentiate multiple benign osteolytic lesions from disseminated bone metastases. Even combined with medical history and multiple imaging results, clinical diagnosis of metastatic lesion remains a challenge. This can affect the treatment procedure. Here the role of skeletal scintigraphy in a case of eosinophilic granuloma is evaluated and concluded that additional attentio

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Marchetta, Sophia, and Ani Ural. "Influence of Osteolytic Lesions on the Fracture Process of the Proximal Femora." Veritas: Villanova Research Journal 6, no. 1 (2024): 12–14. https://doi.org/10.61372/vvrj.v6i1.3004.

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Osteolytic lesions form when metastatic cancer spreads to bone and causes tissue to decay, increasing the risk of pathological fractures. This study aims to provide medical professionals with a guide for determining whether to operate on a femur with detected lesions. 3D-generated Finite Element Analyses were performed on femur models in Abaqus to mimic a stance position. The force required for fracture and stiffness of the bone were extracted from each trial. Exploring other lesion specifications, bone properties, and load application methods can form a more comprehensive method of predicting

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Yogi, Lokesh Kumar, Gaurav B. Mate, and Gagandeep Mahi. "Simple Bone Cyst (Benign Osteolytic Lesion) of 1st Metacarpal: A Rare Case Report." Journal of Orthopaedic Case Reports 12, no. 1 (2022): 102–5. http://dx.doi.org/10.13107/jocr.2022.v12.i01.2640.

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Introduction:A benign cystic lesion, the simple bone cyst (unicameral/essential bone cyst), it may be found in any long bone (most commonly found in femur and proximal humerus), usually in immature skeletal persons. Metacarpal simple bone cyst is an exceedingly rare occurrence and few treatment options have been described for the same. Case Report: A 42-year-old manual laborer male (right hand dominant) came with history of trivial trauma to right hand thumb with hammer. He complained of mild swelling and pain since trauma. On imaging the right hand, an expansive lytic lesion was seen in the m

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Kinoshita, Hideyuki, Takeshi Ishii, Hiroto Kamoda, et al. "Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome with Purely Osteolytic, Not Osteosclerotic, Lesions Mimicking a Malignant Tumor." Case Reports in Rheumatology 2020 (March 28, 2020): 1–6. http://dx.doi.org/10.1155/2020/6316921.

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Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare inflammatory disorder with multiple phenotypes. The syndrome has identifiable radiologic characteristics that are the most important when making a diagnosis. X-rays of cases diagnosed with SAPHO syndrome reveal sclerotic lesions or mixed lytic and sclerotic lesions. Pure osteolytic lesions in SAPHO syndrome are rare, and to the best of our knowledge, no study has reported the radiologic change of purely osteolytic lesions to osteosclerotic lesions over time. Herein, we report on the case of a woman experiencing

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Giddings, C. E. B., D. Bray, S. Stapleton, and H. Daya. "Aneurysmal bone cyst of the spine." Journal of Laryngology & Otology 119, no. 6 (2005): 495–97. http://dx.doi.org/10.1258/0022215054273052.

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The authors present the case of an 11-year-old boy with a painful, rapidly expanding lesion in the posterior triangle of the neck. There was no history of cervical trauma. Computerized tomography of the neck revealed a unicameral (single-chambered) aneurysmal bone cyst involving the C3 vertebra. Treatment was by open resection and curettage; no recurrence was seen at six months. We discuss the natural history, differential diagnosis, radiographic appearance and treatment modalities for this unusual, benign, expanding, osteolytic lesion containing blood-filled cystic cavities.

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Kamath, Jagannath, Harshit Bhaskar Shetty, Arkesh Madegowda, and Anusha S. Bhatt. "Intraosseous schwannoma of the humerus: a rarity yet warrants consideration." BMJ Case Reports 14, no. 9 (2021): e240007. http://dx.doi.org/10.1136/bcr-2020-240007.

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Intraosseous schwannoma is extremely rare that it is not often considered among differential diagnosis for an osteolytic lesion, especially in long bones of the extremities. Amounting to less than 0.2% of all primary bone tumours and less than 200 cases reported so far, with only 3 cases involving the humerus, we hereby report the fourth case. In addition to its rarity, this was the only case of an intraosseous schwannoma involving the humerus bone which presented with a pathological fracture in a 45-year-old woman after sustaining a trivial trauma. Radiological examination revealed a geograph

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Ergelasev, Ivan, Ivan Kuhajda, Dejan Djuric, Danijela Kuhajda, and Sinisa Maksimovic. "Pleural effusion caused by polyostotic fibrous dysplasia involving the ribs, the sternum and the thoracic spine associated with multiple cystic degenerations – a case report." Medical review 72, no. 1-2 (2019): 39–42. http://dx.doi.org/10.2298/mpns1902039e.

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Introduction. Fibrous dysplasia is a noninherited benign skeletal disorder associated with abnormal bone development. Single bone involvement, the monostotic form, accounts for 70 ? 80% of cases, while the polyostotic form, with multiple bone involvement, accounts for 20 ? 30% of cases. Cystic degeneration and occasional aneurysmal bone cyst formation may be found in fibrous dysplasia lesions, particularly in the costal lesions. Case Report. A 51-year-old man presented with acute shortness of breath after sustaining simple chest wall injury. Chest computed tomography showed multiple massive os

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Grammatico, Sara, Emilia Scalzulli, and Maria Teresa Petrucci. "SOLITARY PLASMACYTOMA." Mediterranean Journal of Hematology and Infectious Diseases 9, no. 1 (2017): e2017052. http://dx.doi.org/10.4084/mjhid.2017.052.

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Solitary plasmacytoma is a rare disease characterized by a localized proliferation of neoplastic monoclonal plasma cells, without evidence of systemic disease. It can be subdivided into solitary bone plasmacytoma, if the lesion originates in bone, or solitary extramedullary plasmacytoma, if the lesion involves a soft tissue. Incidence of solitary bone plasmacytoma is higher than solitary extramedullary plasmacytoma. Also prognosis is different: even if both forms respond well to treatment, overall survival and progression free survival of solitary bone plasmacytoma is poorer than solitary extr

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Gupta, Anju, Mark C. Horattas, Ali Reza Moattari, and Scott D. Shorten. "Disseminated Brown Tumors from Hyperparathyroidism Masquerading as Metastatic Cancer: A Complication of Parathyroid Carcinoma." American Surgeon 67, no. 10 (2001): 951–55. http://dx.doi.org/10.1177/000313480106701009.

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Osteitis fibrosa cystica (brown tumors) can be a skeletal manifestation of advanced hyperparathyroidism, including parathyroid cancer. Severe osteitis fibrosa cystica can mimic metastatic bone diseases especially in patients with a history of cancer. Because the treatment and prognosis of these two problems differ greatly considering hyperparathyroidism in the differential diagnosis of patients found to have osteolytic lesions is critical for the appropriate management of these patients. In this case report we describe a patient with a history of renal cell cancer and presumed osteolytic bone

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Kvarda, Peter, Roxa Ruiz, and Beat Hintermann. "Reconstruction of Severe Osteolytic Malleoli using Femoral Head Allograft in a Revision Total Ankle Replacement: A Case Report." Foot & Ankle Orthopaedics 7, no. 4 (2022): 2473011421S0073. http://dx.doi.org/10.1177/2473011421s00738.

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Category: Ankle Arthritis; Ankle; Hindfoot Introduction/Purpose: Case: A 38-year-old male patient presented with severe pain in the left ankle who underwent a total ankle replacement (TAR) and syndesmotic fusion for end-stage ankle osteoarthritis (OA) 13 years ago. Radiographic evaluation showed implant loosening and extensive osteolytic lesion of both malleoli. Revision was performed using a three-component TAR system and reconstruction of the malleoli with femoral head allograft. Methods: N/A Results: N/A Conclusion: Reconstruction of severe osteolytic lesions of the malleoli with femoral he

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Shadaba, Akhtar, and Shabih Zaidi. "Aneurysmal bone cyst of the hyoid." Journal of Laryngology & Otology 106, no. 1 (1992): 71–72. http://dx.doi.org/10.1017/s0022215100118663.

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AbstractAneurysmal bone cyst is a rare lesion usually of the long bones, well documented in the literature. It is a cystic, osteolytic vascular tumour, replete with giant cells and fibrous septa, yet devoid of endothelial lining. It has been reported in the larynx and maxillary sinus. This appears to be the first report Qf an aneurysmal bone cyst occurring in the hyoid bone.

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Nagler, A., Y. Ben-Arieh, B. Brenner, I. Tatarsky, and S. Pollack. "Eosinophilic fibrohistiocytic lesion of bone marrow associated with monoclonal gammopathy and osteolytic lesions." American Journal of Hematology 23, no. 3 (1986): 277–81. http://dx.doi.org/10.1002/ajh.2830230312.

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Gurav, Rajshri U. "Giant Aneurysmal Bone Cyst of the Mandible." Journal of Contemporary Dentistry 6, no. 2 (2016): 149–53. http://dx.doi.org/10.5005/jp-journals-10031-1161.

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ABSTRACT An aneurysmal bone cyst (ABC) is a benign osteolytic bony lesion that commonly affects the long bones with rare presentation in the jaws. The etiopathogenesis of ABC is unsure. Several theories have been suggested like trauma, intramedullary hematoma, alterations in local hemodynamics, reactive malformation, and genetic predisposition. Though ABCs are considered as secondary phenomenon in preexisting benign and malignant bony lesions, intermittent reports of ABCs with primary/denovo origin are generating perplexity in the scenario. Here, we describe a rare case of giant ABC involving

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Sakamoto, Akio, Yoshitsugu Chigusa, Takashi Noguchi, and Shuichi Matsuda. "<i>Salmonella</i> osteomyelitis of the distal radius in a healthy pregnant woman." Journal of Bone and Joint Infection 6, no. 1 (2020): 1–5. http://dx.doi.org/10.5194/jbji-6-1-2020.

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Abstract. Although characteristic, Salmonella is a rare cause of osteomyelitis, especially in healthy individuals. A 25-year old primigravida at 29 weeks' gestation noticed pain and swelling in her right wrist. Her leukocyte count was normal, but her C-reactive protein level was slightly elevated, at 1.1 mg dL−1 (normal range, <0.2 mg dL−1). Plain radiography showed an osteolytic lesion in the distal radius, and magnetic resonance imaging (MRI) showed an extraosseous fluid collection with bone edema in addition to the osseous lesion. After a needle biopsy was performed, the skin overlying t

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