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Journal articles on the topic 'Osteolytic lesion radiology'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Albertsen, A. M., and A. G. Jurik. "Posttraumatic Spinal Osteolysis in Ankylosing Spondylitis as Part of Pseudoarthrosis." Acta Radiologica 37, no. 1P1 (1996): 98–100. http://dx.doi.org/10.1177/02841851960371p119.

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A case of ankylosing spondylitis with pronounced osteolysis of the 12th thoracic vertebral body as part of posttraumatic pseudoarthrosis is described. The appearance of posttraumatic osteolysis simulates a malignant lesion, and it is important to consider the diagnosis in cases of osteolytic lesions of unknown origin.

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Dennis, Ruth, and Jacques Penderis. "RADIOLOGY CORNER-ANAL SAC GAS APPEARING AS AN OSTEOLYTIC PELVIC LESION." Veterinary Radiology Ultrasound 43, no. 6 (2002): 552–53. http://dx.doi.org/10.1111/j.1740-8261.2002.tb01048.x.

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3

Murakami, R., Y. Korogi, Y. Sakamoto, et al. "Skull Metastasis from Hepatocellular Carcinoma." Acta Radiologica 36, no. 4-6 (1995): 597–602. http://dx.doi.org/10.1177/028418519503600459.

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CT, MR and angiographic findings of 6 patients with 9 skull metastases from hepatocellular carcinoma (HCC) were reviewed. In 3 of 6 patients, local pain or neurologic deficit was the initial main manifestation of the disease, although all had been treated for chronic liver disease. In the remaining 3 patients, skull metastases were detected following treatment of HCC. The metastatic lesions appeared as expansile osteolytic masses on CT and as hypervascular masses on angiography. All lesions were demonstrated on MR imaging. Compared with the brain parenchyma, the lesions were iso- or hypointens

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Gonzalez-Billalabeitia, E., M. Quintela-Fandino, I. Alemany, et al. "Coexistence of Two Rare Sarcomas: Primary Leiomyosarcoma of Bone and Epithelioid Hemangioendothelioma of the Liver." Sarcoma 2008 (2008): 1–3. http://dx.doi.org/10.1155/2008/416085.

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A 33-year-old woman sought medical attention for a painful swelling of the left ankle. Plain radiographs revealed an osteolytic lesion involving the left distal tibia. An excisional biopsy provided the diagnosis of leiomyosarcoma in the tibia. A staging work-up was performed and an abdominal CT showed 4 liver hypodense lesions in both lobes with peripheral contrast enhancement. A liver biopsy confirmed the diagnosis of epithelioid hemangioendothelioma of the liver. No association between these two entities has been described before. This case introduces the importance of the pathological confi

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Weber, Marc-André, Alberto Bazzocchi, and Iris-M. Nöbauer-Huhmann. "Tumors of the Spine: When Can Biopsy Be Avoided?" Seminars in Musculoskeletal Radiology 26, no. 04 (2022): 453–68. http://dx.doi.org/10.1055/s-0042-1753506.

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AbstractRegarding osseous tumors of the spine, characteristic morphology is encountered in hemangioma of the vertebral body, osteoid osteoma (OO), osteochondroma, Paget's disease, and bone islands. In these cases, radiologic imaging can make a specific diagnosis and thereby avoid biopsy, especially when the radiologist has chosen the correct imaging modality to establish the diagnosis, such as thin-slice computed tomography in suspected OO. A benign lesion is suggested by a high amount of fat within the lesion, the lack of uptake of the contrast agent, and a homogeneous aspect without solid pa

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Kumar, Prasoon, Sameer Aggarwal, Rajesh Kumar Rajnish, and Saurabh Agarwal. "Tuberculosis of lunate as an isolated intraosseous osteolytic lesion in an adult: a diagnostic challenge." BMJ Case Reports 12, no. 7 (2019): e229597. http://dx.doi.org/10.1136/bcr-2019-229597.

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In an endemic zone of tuberculosis (TB), osseous involvement is a relatively common presentation. Spine and long bones are the the most common nidus of TB. Smaller bones and joints are relatively less involved. Thorough clinical examination and history of typical constitutional symptoms like weight loss, fever and loss of appetite are the diagnostic aids for initiating early treatment. Wrist and hand involvement is a rare occurrence and often presents atypically without any obvious symptoms or signs. This results in delayed diagnosis and worse outcome. TB of lunate without articular involvemen

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Armando, Braven, Rosy Setiawati, Mouli Edward, and Sjahjenny Mustokoweni. "Conventional Radiological Profile of Metastatic Bone Disease Based on Its Histopathological Results: A 3-Year Experience." JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga 14, no. 2 (2023): 76–82. http://dx.doi.org/10.20473/juxta.v14i22023.76-82.

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Highlights:1. The incidence of MBD tends to be more frequent in older ages and in female patients.2. The radiological appearance of a lesion tends to differ depending on its primary tumor.3. Pathological fracture was present in 55.37% of the cases. AbstractIntroduction: Metastasis commonly occurs in the bone, termed metastatic bone disease (MBD). Early diagnosis and intervention are important to prolong and increase the quality of life. Although conventional radiology is less sensitive for diagnosing this disease, it remains the most cost and time-efficient screening method. This study aimed t

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Cystic Angiomatosis: A Radiological Dilemma." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 2 (2024): 61–67. https://doi.org/10.5281/zenodo.15378249.

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<strong>Abstract</strong> Cystic angiomatosis is a rare benign disorder with multifocal hemangiomatous or lymphangiomatous lesions of the axial or appendicular skeleton, spleen, liver, and lungs. Patients usually are asymptomatic and are incidentally detected on radiographs. The spectrum clinical presentation may include splenomegaly, hepatomegaly, cystic hygromas or effusions, and pathological fracture depending on the affected area, they may also have neurological symptoms with vertebral localization and skull lesions. This case report illustrates the prompt and accurate diagnosis of cystic

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Pereira, Tatiana Bernardo Farias, Caio César Da Silva Barros, Humberto Pereira Chaves Neto, et al. "AGGRESSIVE MANDIBULAR OSTEOLYTIC LESION IN A CHILD: A DIAGNOSIS CHALLENGE AND MANAGEMENT." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 134, no. 3 (2022): e156. http://dx.doi.org/10.1016/j.oooo.2022.01.405.

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Abuarqob, Sewar, Brooke Kania, Moutaz Ghrewati, Leena Bondili, Vinod Kumar, and Michael Maroules. "A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint." Radiology Case Reports 17, no. 11 (2022): 4388–91. http://dx.doi.org/10.1016/j.radcr.2022.08.037.

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11

Cotten, A., F. Dewatre, B. Cortet, et al. "Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up." Radiology 200, no. 2 (1996): 525–30. http://dx.doi.org/10.1148/radiology.200.2.8685351.

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Goutzanis, Lampros, John Apostolidis, Chara Giatra, Evanthia Chrysomali, and Dimitrios Deskos. "A case of systemic precursor T-cell lymphoblastic lymphoma presenting with single tooth mobility." SAGE Open Medical Case Reports 8 (January 2020): 2050313X2092796. http://dx.doi.org/10.1177/2050313x20927961.

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Lymphoblastic lymphoma, seen primarily in children or young adults, is a type of non-Hodgkin lymphoma that originates from B or T lymphocyte precursors and rarely occurs in the oral cavity. A case of systemic precursor T-cell lymphoblastic lymphoma mimicking periodontitis of a lower second molar in a 20-year-old adult is currently presented. The case was initially misdiagnosed as periodontal disease and treated with tooth extraction by a dentist. Re-evaluation of the patient due to worsening of symptoms lead to cone beam computed tomography scanning that thoroughly revealed an extended osteoly

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Liu, Yu, and Kaicheng Li. "Solitary plasmacytoma of maxillofacial bones: correlation of CT features with pathological findings." Dentomaxillofacial Radiology 49, no. 1 (2020): 20190277. http://dx.doi.org/10.1259/dmfr.20190277.

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Objective: To explore the CT features of solitary plasmacytoma (SP) of maxillofacial bones and correlation with pathological findings. Methods and materials: We retrospectively reviewed the clinical, CT and pathological features of SP in the maxillofacial bones. 16 patients with clinically and histologically proven SP of maxillofacial bones were involved. They were aged from 27 to 79 years old (median 55.5 years old), and included 12 males and 4 females (males vs females: 3:1). All patients performed CT examination, in whom 13 patients underwent enhanced scanning and 3 plain scanning. The CT i

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Lee, Jung A., Seung J. Huh, Dongryul Oh, and Duk S. Bae. "Osteoradionecrosis after three-dimensional conformal radiotherapy for recurrent cervical cancer presenting as a progressive osteolytic lesion." Annals of Nuclear Medicine 22, no. 2 (2008): 139–41. http://dx.doi.org/10.1007/s12149-007-0090-3.

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15

Garnon, Julien, Laurence Meylheuc, Pierre De Marini, et al. "Subjective Analysis of the Filling of an Acetabular Osteolytic Lesion Following Percutaneous Cementoplasty: Is It Reliable?" CardioVascular and Interventional Radiology 43, no. 3 (2019): 445–52. http://dx.doi.org/10.1007/s00270-019-02397-1.

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Suntharalingam, Saravanabavaan, Christian Mikat, Axel Wetter, et al. "Whole-body ultra-low dose CT using spectral shaping for detection of osteolytic lesion in multiple myeloma." European Radiology 28, no. 6 (2018): 2273–80. http://dx.doi.org/10.1007/s00330-017-5243-8.

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Østergaard, Brian, Julie R. Mortensen, Anne L. Nielsen, et al. "18F-FDG-PET/CT and Osteolytic Bone Disease in Multiple Myeloma." Blood 128, no. 22 (2016): 5622. http://dx.doi.org/10.1182/blood.v128.22.5622.5622.

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Abstract Introduction: FDG-PET/CT is a promising methodology for staging, prognostication, and response evaluation in multiple myeloma (MM). The number of focal FDG lesions and the intensity of FDG uptake (standard uptake value, SUV) at diagnosis are informative of disease aggressiveness. Osteolytic bone disease is a hallmark of MM. Hypothetically; increased focal metabolic activity will precede, induce and correlate to osteolytic lesions. We aimed to elucidate the association between focal FDG positive lesions and osteolytic bone disease in MM patients. Methods: Twenty-two newly diagnosed MM

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Kumar, Rajnand, Nitish Kumar, Ajay Bharti, Sudhir Shyam Kushwaha, and Vivek Kumar. "Giant Cell Tumor of First Metatarsal: A Rare Case Report with Literature Review." Journal of Orthopaedic Case Reports 14, no. 9 (2024): 45–48. http://dx.doi.org/10.13107/jocr.2024.v14.i09.4724.

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Introduction: Giant cell tumor (GCT) is a benign locally aggressive tumor with features of frequent recurrence and metastatic potential. GCT of small bones of hand and feet is rare with high recurrence and potential to metastasis. This study aims to provide a case report of GCT of the first metatarsal treated with wide excision, autologous fibular grafting, and fixation with locking plate. Case Report: An 18-year-old male patient presented with progressive swelling over the dorsomedial aspect of foot for 1 year. Upon clinical examination, the swelling was firm with local signs suggestive of a

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Kinoshita, Hideyuki, Takeshi Ishii, Hiroto Kamoda, et al. "Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome with Purely Osteolytic, Not Osteosclerotic, Lesions Mimicking a Malignant Tumor." Case Reports in Rheumatology 2020 (March 28, 2020): 1–6. http://dx.doi.org/10.1155/2020/6316921.

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Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare inflammatory disorder with multiple phenotypes. The syndrome has identifiable radiologic characteristics that are the most important when making a diagnosis. X-rays of cases diagnosed with SAPHO syndrome reveal sclerotic lesions or mixed lytic and sclerotic lesions. Pure osteolytic lesions in SAPHO syndrome are rare, and to the best of our knowledge, no study has reported the radiologic change of purely osteolytic lesions to osteosclerotic lesions over time. Herein, we report on the case of a woman experiencing

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Gibbons, C. L. M. H., M. Petra, R. Smith, and N. A. Athanasou. "Bisphosphonate Treatment of Benign Multifocal and Unifocal Osteolytic Tumours of Bone." Sarcoma 7, no. 1 (2003): 35–41. http://dx.doi.org/10.1080/1357714031000114165.

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Growth of benign tumours and tumour-like lesions of bone results in osteolysis which may cause pathological fracture. Bisphosphonates are anti-osteolytic agents which have proved effective in the treatment of number of osteolytic conditions. In this study we report the results of treatment with the aminobisphosphonate, pamidronate, of three benign osteolytic tumours of bone, two cases of fibrous dysplasia and one of Langerhans cell histiocytosis. In all three cases there was clinical and radiological improvement following treatment. Radiologically, bone lesions did not exhibit progressive enla

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Anselmetti, Giovanni Carlo. "Percutaneous Vertebral Augmentation Assisted by PEEK Implant in Painful Osteolytic Vertebral Metastasis Involving the Vertebral Wall: Experience on 40 Patients." Pain Physician 4;16, no. 4;7 (2013): E397—E404. http://dx.doi.org/10.36076/ppj.2013/16/e397.

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Background: Vertebral metastases are associated with significant pain, disability, and morbidity. Open surgery for fracture stabilization is often inappropriate in this cancer population due to a poor risk-benefit profile, particularly if life expectancy is short. Vertebroplasty and kyphoplasty are appealing adjunctive procedures in patients with malignancy for alleviation of intractable pain. However, these patients have a higher risk of serious complications, notably cement extravasation. Study Design: We prospectively evaluated clinical results of polyetheretherketone (PEEK) implant (Kiva)

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Paycha, F., and A. Girma. "Pattern-oriented approach in hybrid imaging (bisphosphonates-(99mTc) SPECT/CT and Fluoride-(18F) PET/CT) according to bone abnormality phenotype: The sclerotic/osteoblastic lesion and the osteolytic/osteoclastic lesion." Médecine Nucléaire 35, no. 5 (2011): 332–35. http://dx.doi.org/10.1016/j.mednuc.2011.02.020.

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23

Thomas, D. M., S. Chawla, K. Skubitz, et al. "Denosumab for the treatment of giant cell tumor (GCT) of bone: Final results from a proof-of-concept, phase II study." Journal of Clinical Oncology 27, no. 15_suppl (2009): 10510. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.10510.

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10510 Background: GCT of bone is a primary osteolytic bone tumor with low metastatic potential that is associated with significant skeletal morbidity. GCT is rich in stromal cells that express RANKL, a key mediator of osteoclast activation. In this open-label, study, we investigated whether denosumab, a fully human monoclonal antibody against RANKL, could have a potential therapeutic effect on giant cell histology for patients with GCT. Methods: In this single-arm study, 37 patients with measurable or unresectable GCT received denosumab 120 mg subcutaneously once monthly with loading doses on

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Vinayachandran, Divya, and Sathasivasubramanian Sankarapandian. "Multiple Osteolytic Lesions." Journal of Clinical Imaging Science 3 (August 31, 2013): 6. http://dx.doi.org/10.4103/2156-7514.117460.

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Several systemic diseases initially present with various oral manifestations. Investigation of these oral symptoms may at times lead to the diagnosis of grave underlying life-threatening conditions. We present one such case, where the patient manifested with gross enlargement of the mandible, along with lesions in the lower limbs. These lesions were the initial manifestation and on further investigations the patient was diagnosed with multiple myeloma.

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Schweitzer, M. E., and D. M. Deely. "Percutaneous biopsy of osteolytic lesions: use of a biopsy gun." Radiology 189, no. 2 (1993): 615–16. http://dx.doi.org/10.1148/radiology.189.2.8210398.

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26

Bahk, Won Jong, Sae Jung Na, In Yong Whang, Yongju Kim, and Kyung Jin Seo. "Aortic Angiosarcoma Manifesting as Multiple Musculoskeletal Metastases: A Case Report." Diagnostics 14, no. 8 (2024): 805. http://dx.doi.org/10.3390/diagnostics14080805.

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Aortic angiosarcomas are rare. Due to its rarity and metastatic presentation, it is difficult to diagnose metastatic aortic angiosarcoma. We describe the clinicopathological and radiologic features of a metastatic aortic angiosarcoma presenting as musculoskeletal metastases. A 59-year-old male patient presented with left thigh pain. Plain radiographs revealed multifocal osteolytic lesions in the left femur shaft. Abdominopelvic computed tomography showed a lobulated osteolytic lesion in the left iliac bone. Magnetic resonance images revealed multifocal soft tissue lesions in the thigh musculat

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Ji, Mengmeng, Mei Wang, Yi-Hsuan Shih, et al. "From criteria to clinic: How updated SLiM CRAB criteria influence multiple myeloma diagnostic activity." Journal of Clinical Oncology 42, no. 16_suppl (2024): 7556. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.7556.

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7556 Background: Multiple myeloma (MM) is a plasma cell malignancy, which is preceded by asymptomatic, precursor state of monoclonal gammopathy of undetermined significance (MGUS). Once diagnosed with MGUS, monitoring for progression to MM is recommended. The diagnostic criteria for active MM include presence of ≥1 CRAB features (hypercalcemia, renal failure, anemia, or one or more osteolytic bone lesions on skeletal radiology, CT or PET/CT imaging) in addition to clonal plasma cells on bone marrow. In 2014, the International Myeloma Working Group (IMWG) added SLiM to the criteria: clonal bone

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Balasubramanian, Subalakshmi, Ujjvala Kalluri, and Nellaiyappan Balsubramanian. "Analysis of synovial biopsies in osteomyelitis in a tertiary care center." IP Journal of Diagnostic Pathology and Oncology 6, no. 2 (2021): 138–43. http://dx.doi.org/10.18231/j.jdpo.2021.030.

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To differentiate, grade and evaluate the histologic features seen in the biopsy specimens of osteomyelitis patients in a tertiary care centre according to their abundance/severity with the help of a pre-established scoring system and to correlate those features with their radiology and serology findings. 52 synovial biopsy specimens of patients suffering from osteomyelitis, from the year 2015 to 2017, were reviewed from the institute’s case files. The histopathological features were analyzed and a diagnostic criterion was set using a grading system involving five histological features to diffe

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Jang, Gi Wuk, and Sung Hyun Noh. "Gorham-Stout Disease in a Middle-Aged Patient Treated by Posterior Lateral Fusion: A Case Report and Literature Review." Nerve 7, no. 2 (2021): 106–9. http://dx.doi.org/10.21129/nerve.2021.7.2.106.

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Gorham-Stout disease (GSD) is a rare progressive osteolytic disease with intraosseous lymphangiomatosis. A previously healthy 55-year-old woman presented with left leg hypoesthesia and upper back pain. k pain, back pain, and bilateral shoulder pain. In radiologic examination, there was an osteolytic lesion in T3, 4, 5, 6 vertebra. And a dislocation in the T3/4 vertebrae and a compression fracture in the T4 vertebra were founded. She was treated with posterolateral fusion (PLF) from C7 to T7. For 1 year, she had no specific symptoms but a new osteolytic lesion was found on thoracic T8 on 1 year

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Ehara, S., JS Khurana, SV Kattapuram, AE Rosenberg, GY el-Khoury, and DI Rosenthal. "Osteolytic lesions of the patella." American Journal of Roentgenology 153, no. 1 (1989): 103–6. http://dx.doi.org/10.2214/ajr.153.1.103.

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Solav, Shrikant. "Bone Scintiscanning in Osteolytic Lesions." Clinical Nuclear Medicine 29, no. 1 (2004): 12–20. http://dx.doi.org/10.1097/01.rlu.0000102743.49568.1d.

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Baron, A. L., L. S. Steinbach, P. E. LeBoit, C. M. Mills, J. H. Gee, and T. G. Berger. "Osteolytic lesions and bacillary angiomatosis in HIV infection: radiologic differentiation from AIDS-related Kaposi sarcoma." Radiology 177, no. 1 (1990): 77–81. http://dx.doi.org/10.1148/radiology.177.1.2399342.

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Rabelo, Nicollas, Vinicius Trindade Gomes da Silva, Marcelo Prudente do Espírito Santo, et al. "Orbit ossifying fibroma – Case report and literature review." Surgical Neurology International 11 (February 28, 2020): 35. http://dx.doi.org/10.25259/sni_492_2019.

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Background: Ossifying fibroma (OF) is benign bone lesions, most frequent in young children, more common in the maxillary sinus and mandible (75–89%), the pathogenesis of the tumor is not clear, there are many subtypes of OF. This paper aims to report an OF a case and literature review. Case Description: Male, 19 years old, with a progressive history proptosis since 2012, diagnosed as a right supraorbital lesion at an external service and assigned to conservative management. Then, he evolved with double vision, which worsened in February of 2018, associated with a moderate headache. On admissio

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Devaraj, Akshitha, and Hassen Al-Sader. "Osteolytic lesions: Multiple myeloma or prostate cancer?" Radiology Case Reports 18, no. 4 (2023): 1485–89. http://dx.doi.org/10.1016/j.radcr.2023.01.054.

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Khan, Abed Hussain, Rafla Afrose, Mujahida Rahman, Mohammad Ferdous Ur Rahaman, Md Shababul Huda Chowdhury, and M. A. Jalil Chowdhury. "Non-secretory multiple myeloma with extramedulary plasmocytoma." Bangabandhu Sheikh Mujib Medical University Journal 6, no. 1 (2016): 66. http://dx.doi.org/10.3329/bsmmuj.v6i1.29089.

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Non-secretory multiple myeloma (NSMM) is an uncommon variation of the classic form of multiple myeloma (MM) that has au analogous clinical and radiologic presentation except for the absence of the M-protein in sernm and/or urine. NSMM may have or not detectable monoclonal free light chain in urine/serum. We describe here a case of a 46-year-old woman who presented with back pain and lower limb weakness. A tumour lesion at DI level and multiple osteolytic bone lesions were found. This woman had no other symptoms and her basic blood biochemistry were nonnal. She had normal serum and urine protei

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Doganis, Dimitrios, Margarita Baka, Maria Tsolia, et al. "Multifocal Aeromonas Osteomyelitis in a Child with Leukemia." Case Reports in Infectious Diseases 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/8159048.

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Aeromonas hydrophilais a Gram negative organism causing both intestinal and extraintestinal disease. The case of a 14-year-old girl with underlying immunodeficiency and leukemia who developed systemicA. hydrophilainfection is described in this report. While in deep bone marrow aplasia she developed fever, severe pain in the lower extremities, and swelling of the left femur. Blood culture showedEscherichia coliandA. hydrophilawhereas pus culture from the soft tissue swelling showed the presence ofA. hydrophila. Imaging studies showed diffuse osteolytic lesions. Patient received 5 months of intr

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Baykul, Timuçin, Hasan Onur Simsek, Muge Cina Aksoy, and Cagri Can. "Intraosseous Schwannoma of the Mandible." International Journal of Experimental Dental Science 1, no. 1 (2012): 48–50. http://dx.doi.org/10.5005/jp-journals-10029-1012.

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ABSTRACT Schwannoma originates from Schwann cells of peripheral nerve sheaths and account for 1% of benign primary bone tumors. The site most commonly involved is the mandible. We present a 47-year-old woman with schwannoma at mandible. Neurosensory examination comprised paresthesia at left side of the mandible. Radiologic examination showed a well-defined unilocular osteolytic lesion which located in the left side of the mandible. The lesion was surgically curetted. The patient is under our follow-up. In this report, clinical and histological features and treatment of the schwannoma are discu

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Lima Júnior, Francisco Valtenor Araújo, Leonor Garbin Savarese, Lucas Moretti Monsignore, Roberto Martinez, and Marcello Henrique Nogueira-Barbosa. "Computed tomography findings of paracoccidiodomycosis in musculoskeletal system." Radiologia Brasileira 48, no. 1 (2015): 1–6. http://dx.doi.org/10.1590/0100-3984.2014.0049.

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Objective: To evaluate musculoskeletal involvement in paracoccidioidomycosis at computed tomography. Materials and Methods: Development of a retrospective study based on a review of radiologic and pathologic reports in the institution database. Patients with histopathologically confirmed musculoskeletal paracoccidioidomycosis and submitted to computed tomography were included in the present study. The imaging findings were consensually described by two radiologists. In order to avoid bias in the analysis, one patient with uncountable bone lesions was excluded from the study. Results: A total o

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Peng, Xinsheng, Liyan Chen, Hong Du, Yingrong Lai, Fobao Li, and Xuenong Zou. "Malignant Transformation of Benign Intraosseous Schwannoma in the Cervical Spine: A Case Report with an Immunohistochemical Study." International Surgery 96, no. 4 (2011): 337–44. http://dx.doi.org/10.9738/cc42.1.

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Abstract Although 3% to 30% of lesions in von Recklinghausen disease undergo malignant transformation, malignant transformation of benign solitary schwannoma is extremely rare. We reported a case of recurrence and malignant transformation in a benign intraosseous schwannoma arising in the cervical spine of a 44-year-old man. The patient presented giant tumor in the C3 vertebral body with aggressive, expansile, and osteolytic destruction and relapsed 2 years after surgical resection and spinal reconstruction. Clinical data, radiologic characteristics, surgical management, histopathologic and im

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Chinchilla, Evelyn Alarcon, Marie-Pascale Gourde, Karine Turcotte, Steve Mathieu, and Mohamed Amin-Hashem. "Case of Erdheim–Chester presenting with xanthelasma-like eruption and osteolytic bone lesions: A case report." SAGE Open Medical Case Reports 7 (January 2019): 2050313X1984521. http://dx.doi.org/10.1177/2050313x19845217.

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Erdheim–Chester disease is a rare multisystemic non-Langerhans cell histiocytosis presenting 95% with skeletal lesions. Erdheim–Chester disease is due to mutations in the RAS-MEK-ERK pathway where 50% are due to BRAF-V600E mutations. Typical histopathological, clinical, and radiologic features are necessary for the diagnosis of Erdheim–Chester disease. Prognosis depends on the extent of the systemic involvement, and central nervous system involvement has a poorer outcome. We present a 30-year-old Moroccan woman with diabetes insipidus, bone marrow, and asymmetrical axial osteolytic bone lesion

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Chan, F. L., E. K. W. Ho, D. Fang, L. C. S. Hsu, J. C. Y. Leong, and H. Ngan. "Spinal Pseudarthrosis in Ankylosing Spondylitis." Acta Radiologica 28, no. 4 (1987): 383–88. http://dx.doi.org/10.1177/028418518702800403.

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Spinal pseudarthrosis is an important mechanical complication in longstanding ankylosing spondylitis. Thirty-five patients with 40 lesions were studied. Three lesions through vertebral bodies resulted from complete fractures. The rest occurred at interspaces, more common at the lower thoracic and upper lumbar segments. Double pseudarthrotic lesions were observed in 5 patients. Progressive osteolysis of the anterior elements was prominent, with variable sclerosis, osteophytes, vacuum phenomenon, subluxation and fragmentation. A posterior element weak link, as a bony break or facet joint non-fus

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Guild, Theodore, Leonard T. Onsen, Marie Rivers, Rebecca Cheski, Brian Bear, and Rolando Izquierdo. "Detritic Synovitis With Osteolysis Leading to Pathologic Fracture and Deltoid Avulsion Following Total Shoulder Arthroplasty." Journal of Shoulder and Elbow Arthroplasty 2 (January 2018): 247154921880808. http://dx.doi.org/10.1177/2471549218808088.

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Purpose To report a unique case of detritic synovitis with associated lytic lesion leading to pathologic fracture of the acromion and deltoid avulsion following total shoulder arthroplasty (TSA). Methods An institutional review board-approved retrospective case analysis was performed using Electronic Medical Records (EMR) sourced pathology and radiology results, clinic notes, and surgical reports. Case Description: We present the case of a 79-year-old woman with a surgical history significant for TSA who presented with new onset of shoulder pain. The patient was found to have a lytic lesion in

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Cohn, Adelina-Maria, Simona Costache, and Doina Mihaela Pop. "Chondroblastoma of bone: case presentation, immunohistochemistry findings and literature review." Oncolog-Hematolog.ro 3, no. 1 (2020): 22–29. http://dx.doi.org/10.26416/onhe.52.3.2020.3712.

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Chondroblastoma is a rare benign cartilage-producing tumor, with an incidence of approximatively 1% of all primary bone tumors. It arises mostly in the second decade of life, affecting mainly the ends of the long tubular bones. We present two cases of chondroblastoma diagnosed and treated in the “Foişor” Orthopedics, Traumatology and Oesteoarticular TB Clinical Hospital, Bucharest, Romania. The purpose of this study is to contrast two different forms of presentation of the same histologic entity: one case of a 19-year-old male patient with a chondroblastoma located in the proximal hume

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Cohn, Adelina-Maria, Simona Costache, and Doina Mihaela Pop. "Chondroblastoma of bone: case presentation, immunohistochemistry findings and literature review." Oncolog-Hematolog.ro 3, no. 1 (2020): 22–29. http://dx.doi.org/10.26416/onhe.52.3.2020.3712.

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Chondroblastoma is a rare benign cartilage-producing tumor, with an incidence of approximatively 1% of all primary bone tumors. It arises mostly in the second decade of life, affecting mainly the ends of the long tubular bones. We present two cases of chondroblastoma diagnosed and treated in the “Foişor” Orthopedics, Traumatology and Oesteoarticular TB Clinical Hospital, Bucharest, Romania. The purpose of this study is to contrast two different forms of presentation of the same histologic entity: one case of a 19-year-old male patient with a chondroblastoma located in the proximal hume

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Ivan, Doina, Antonio Neto, Luciano Lemos, and Arpan Gupta. "Erdheim-Chester Disease: A Unique Presentation With Liver Involvement and Vertebral Osteolytic Lesions." Archives of Pathology & Laboratory Medicine 127, no. 8 (2003): e337-e339. http://dx.doi.org/10.5858/2003-127-e337-edaupw.

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Abstract Erdheim-Chester disease is a very rare xanthogranulomatous, non-Langerhans cell systemic histiocytosis with an unknown etiology and pathogenesis. Histologically, it is characterized by a diffuse infiltration with large, foamy histiocytes, rare Touton-like giant cells, lymphocytic aggregates, and fibrosis. The histiocytes differ from the Langerhans cell group in ontogenesis, immunohistochemistry (positive for CD68 and negative for CD1a and S100 protein), and ultrastructural appearance (lack of Birbeck granules). Although most of the cases have symmetric osteosclerosis of the long bones

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Radhakrishnan, Neetu, and Mark A. Hoffman. "Hypercalcemia in B-Cell Chronic Lymphocytic Leukemia: Report of a Case and Review of the Literature." Blood 106, no. 11 (2005): 5009. http://dx.doi.org/10.1182/blood.v106.11.5009.5009.

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Abstract A 53 year old man with Rai stage IV CLL was being treated with R-HyperCVAD when he presented between cycles with fatigue, lethargy and pancytopenia. Clinical examination revealed diffuse adenopathy and splenomegaly. Serum calcium was 13.6 mg/dl, phosphorus level was 2.7 mg/dl, and alkaline phosphatase was 54 U/L. PTH was 4 Units/L (10–65), PTHrP &lt; 0.2 pmole/L (0–1.9), 1–25 (OH) Vitamin D &lt; 10pgm/ml (22–67). Quantitative immunglobulins: IgA 10 mg/dl, IgG 252 mg/dl, IgM 50 mg/dl. Immunofixation revealed a faint IgG lambda paraprotein. There were no lytic lesions on skeleta

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Park, Yoo Jung, Kwang Hwan Park, Jae Han Park, Seung Hwan Han, Sang B. Kim, and Jin Woo Lee. "Management of Periprosthetic Osteolysis after Total Ankle Arthroplasty." Foot & Ankle Orthopaedics 5, no. 4 (2020): 2473011420S0037. http://dx.doi.org/10.1177/2473011420s00378.

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Category: Ankle Arthritis; Ankle Introduction/Purpose: Periprosthetic osteolysis in total ankle arthroplasty (TAA) is a substantial problem. It may cause implant failure and has potential to affect long-term implant survival. To prevent major revisional arthroplasty, it is important to make an early diagnosis of osteolysis and decide an appropriate timing of surgical intervention such as bone graft. We report our updated result of bone graft for osteolysis after TAA associated with clinical and radiologic outcome. Methods: We retrospectively evaluated our consecutive series of 440 primary TAAs

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Park, Yoo Jung, Dong-Woo Shim, Yeokgu Hwang, and Jin Woo Lee. "The Fate of Bone Graft for Periprosthetic Osteolysis in Total Ankle Arthroplasty." Foot & Ankle Orthopaedics 2, no. 3 (2017): 2473011417S0000. http://dx.doi.org/10.1177/2473011417s000070.

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Category: Ankle Arthritis Introduction/Purpose: Periprosthetic osteolysis in total ankle arthroplasty (TAA) is a substantial problem. It may cause implant failure and has potential to affect long-term implant survival. To prevent major revisional arthroplasty, it is important to make an early diagnosis of osteolysis and decide an appropriate timing of surgical intervention such as bone graft. We report our experience of bone graft for osteolysis after TAA associated with clinical and radiologic outcome. Methods: Between May 2004 and Oct. 2013, 238 primary TAA were performed on 219 patients. We

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Oppenheim, Ian M., Astrid Medina Canon, William Barcenas, et al. "Bilateral symmetrical cortical osteolytic lesions in two patients with Gaucher disease." Skeletal Radiology 40, no. 12 (2011): 1611–15. http://dx.doi.org/10.1007/s00256-011-1260-x.

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Garnon, Julien, and Jack W. Jennings. "Percutaneous Consolidation for Extraspinal Osteolytic Lesions: To Cementoplasty and Beyond." Journal of Vascular and Interventional Radiology 31, no. 4 (2020): 659–60. http://dx.doi.org/10.1016/j.jvir.2019.12.014.

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