Academic literature on the topic 'Osteoponten'

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Journal articles on the topic "Osteoponten"

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Chiu, Tai-Jan, Hung-I. Lu, Chang-Han Chen, et al. "Osteopontin Expression Is Associated with the Poor Prognosis in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma Receiving Preoperative Chemoradiotherapy." BioMed Research International 2018 (2018): 1–9. http://dx.doi.org/10.1155/2018/9098215.

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Background. The osteopontin has been involved in therapeutic resistance in a variety of cancers. But, the significance of osteopontin expression on the prognosis of patients with locally advanced esophageal squamous cell carcinoma (ESCC) receiving chemoradiotherapy is unclear.Methods.In 80 patients with locally advanced ESCC receiving preoperative chemoradiotherapy between 1999 and 2012, osteopontin expression was evaluated by immunohistochemistry and correlated with treatment outcome. The functional role of osteopontin in ESCC cell lines was determined by osteopontin-mediated siRNA.Results. O
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Sodek, J., B. Ganss, and M. D. McKee. "Osteopontin." Critical Reviews in Oral Biology & Medicine 11, no. 3 (2000): 279–303. http://dx.doi.org/10.1177/10454411000110030101.

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Osteopontin (OPN) is a highly phosphorylated sialoprotein that is a prominent component of the mineralized extracellular matrices of bones and teeth. OPN is characterized by the presence of a polyaspartic acid sequence and sites of Ser/Thr phosphorylation that mediate hydroxyapatite binding, and a highly conserved RGD motif that mediates cell attachment/signaling. Expression of OPN in a variety of tissues indicates a multiplicity of functions that involve one or more of these conserved motifs. While the lack of a clear phenotype in OPN "knockout" mice has not established a definitive role for
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Scatena, Marta, Lucy Liaw, and Cecilia M. Giachelli. "Osteopontin." Arteriosclerosis, Thrombosis, and Vascular Biology 27, no. 11 (2007): 2302–9. http://dx.doi.org/10.1161/atvbaha.107.144824.

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Szalay, Gudrun, Martina Sauter, Michael Haberland, et al. "Osteopontin." Circulation Research 104, no. 7 (2009): 851–59. http://dx.doi.org/10.1161/circresaha.109.193805.

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Shaheen, Mazen, and Neal L. Weintraub. "Osteopontin." Arteriosclerosis, Thrombosis, and Vascular Biology 27, no. 3 (2007): 439–41. http://dx.doi.org/10.1161/01.atv.0000258640.30287.7b.

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Demer, Linda L., and Yin Tintut. "Osteopontin." Circulation Research 84, no. 2 (1999): 250–52. http://dx.doi.org/10.1161/01.res.84.2.250.

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Chellaiah, M. A., and K. A. Hruska. "Osteopontin." Drug News & Perspectives 11, no. 6 (1998): 350. http://dx.doi.org/10.1358/dnp.1998.11.6.863656.

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Vogt, Mario HJ, Joop ten Kate, Roosmarie JM Drent, Chris H. Polman, and Raymond Hupperts. "Increased osteopontin plasma levels in multiple sclerosis patients correlate with bone-specific markers." Multiple Sclerosis Journal 16, no. 4 (2010): 443–49. http://dx.doi.org/10.1177/1352458509359723.

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The pro-inflammatory cytokine osteopontin has been found to be highly expressed in multiple sclerosis lesions and plasma levels are increased during relapses in relapse-onset multiple sclerosis patients. The objective was to determine the relationship between osteopontin plasma and cerebrospinal fluid levels in relation to the immunoglobulin G index. In addition, osteopontin plasma levels were compared with osteopontin mRNA levels in peripheral blood mononuclear cells and bone-specific markers to analyse whether osteopontin may be peripherally produced. Osteopontin and bone-specific markers we
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Feldreich, Tobias, Axel C. Carlsson, Johanna Helmersson-Karlqvist, et al. "Urinary Osteopontin Predicts Incident Chronic Kidney Disease, while Plasma Osteopontin Predicts Cardiovascular Death in Elderly Men." Cardiorenal Medicine 7, no. 3 (2017): 245–54. http://dx.doi.org/10.1159/000476001.

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Background and Objectives: The matricellular protein osteopontin is involved in the pathogenesis of both kidney and cardiovascular disease. However, whether circulating and urinary osteopontin levels are associated with the risk of these diseases is less studied. Design, Setting, Participants, and Measurements: A community-based cohort of elderly men (Uppsala Longitudinal Study of Adult Men [ULSAM]; n = 741; mean age: 77 years) was used to study the associations between plasma and urinary osteopontin, incident chronic kidney disease, and the risk of cardiovascular death during a median of 8 ye
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Merry, K., R. Dodds, A. Littlewood, and M. Gowen. "Expression of osteopontin mRNA by osteoclasts and osteoblasts in modelling adult human bone." Journal of Cell Science 104, no. 4 (1993): 1013–20. http://dx.doi.org/10.1242/jcs.104.4.1013.

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Over recent years several non-collagenous matrix proteins of bone have been isolated and characterized. One of these proteins, osteopontin, has been shown to be synthesized by osteoblasts and deposited in the bone matrix where it is thought to bind to hydroxyapatite. However much of the functional evidence is circumstantial, and the precise function of osteopontin has not been fully elucidated. We have used in situ hybridization techniques to investigate the expression of osteopontin mRNA in a variety of human bone tissues. Cryostat sections of human osteophyte and osteoclastoma tissue were hy
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Dissertations / Theses on the topic "Osteoponten"

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Mateus, Natasha D'Andrea. "Estudo ultra-estrutural e imunocitoquímico das reações do periodonto de molares de ratos submetidos a estímulos contínuos de vestibularização em tempos prolongados." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42134/tde-15062009-154657/.

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Acreditava-se que a reparação do osso alveolar durante a movimentação ortodôntica só ocorresse após a diminuição da carga aplicada. No entanto, recentemente foi observado reparação do osso alveolar utilizando força contínua. Osteopontina é uma proteína não colágena da matriz com importante papel na remodelação óssea. Para analisar as reações no periodonto de sustentação e a distribuição de OPN, uma força contínua de 15cN foi aplicada aos primeiros molares superiores de ratos por 12d, 15d e 18d. Como controle, outros animais não tiveram seus molares movimentados. As maxilas foram processadas pa
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Teixeira, Lucas Novaes 1981. "Estudo da expressão de osteopontina em sistemas de coculturas de células osteoblásticas e epiteliais neoplásicas humanas e seus efeitos sobre o fenótipo neoplásico e a ativação osteoclástica." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288466.

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Orientador: Paulo Tambasco de Oliveira<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-26T15:44:04Z (GMT). No. of bitstreams: 1 Teixeira_LucasNovaes_D.pdf: 3520593 bytes, checksum: e42a5497740bc09fe80b9a6a035947df (MD5) Previous issue date: 2015<br>Resumo: O carcinoma espinocelular (CEC) oral representa a neoplasia maligna mais prevalente das estruturas bucais, podendo invadir o tecido ósseo e promover sua reabsorção em até 56% dos casos. A expressão da proteína matricelular osteopontina (OPN) tem sido rel
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Marques, Erika Afonso Costa Cortez. "Estudo da expressão e participação de osteopontina durante a interação taquizoíto de Toxoplasma gondii célula hospedeira." Universidade do Estado do Rio de Janeiro, 2007. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=2266.

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Toxoplasma gondii é um parasito do filo Apicomplexa que infecta uma grande variedade de hospedeiros, incluindo os humanos. O parasito invade a célula hospedeira por penetração ativa, com a participação das proteínas de suas organelas secretoras durante esse processo. Até o momento, somente um número limitado de proteínas secretoras tem sido descoberto, além disso, as moléculas efetoras envolvidas na invasão e sobrevivência do parasito não estão completamente compreendidas. A osteopontina (OPN) é uma glicofosfoproteína adesiva secretada, multifuncional, que contém o domínio arginina-glicina-áci
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Rothbarth, Claudia Pires. "Efeito do alendronato de sódio em molares de rato em formação após luxação lateral." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/23/23140/tde-19122013-153054/.

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Os bisfosfonatos são drogas capazes de inibir a reabsorção óssea por meio de seu efeito direto sobre as células ósseas, interferindo na dinâmica dos tecidos mineralizados. O alendronato (ALN), um tipo de bisfosfonato nitrogenado, foi utilizado com o objetivo de investigar os seus efeitos sobre os tecidos dentários e periodontais após luxação lateral de molares com as raízes em desenvolvimento. Ratos Wistar com 21 dias de idade tiveram os segundos molares superiores luxados lateralmente. Doses diárias de 2,5 mg / kg de ALN começaram no dia seguinte à luxação; os controles receberam solução sali
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Smith, Laura Lee. "Osteopontin structure and function /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/6322.

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Myers, Daniel. "The Role of Osteopontin in Vascular Remodeling." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/MyersDL2004.pdf.

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Barbosa, Ana Claudia da Silva. "Estudo das proteínas ósseas não colágenas no processo de reparação óssea alveolar em ratos idosos." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-21112013-103224/.

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O trabalho teve como objetivo avaliar e quantificar o tecido ósseo neoformado, a distribuição e a importância das proteínas não colágenas (osteocalcina, osteopontina e osteonectina) no processo de reparação tecidual do alvéolo dental de ratos Wistar idosos após exodontia. Para sua realização, foram utilizados 80 Rattus Norvegicus albinus, linhagem Wistar, machos. Os animais foram distribuídos em dois grupos: Grupo Controle, correspondente a animais com 60 dias de vida; e Grupo Experimental correspondente aos animais com 2 anos de vida (700 dias em média). Cada grupo foi dividido em 4 subgrupos
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Moye, Victoria Ellen. "Mode of action of metastasis-inducing-DNAs in the upregulation of OPN expression." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250383.

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Leitão, Glauber Moreira. "Osteopontina como marcador de resposta à radioterapia e quimioterapia em pacientes com câncer de cabeça e pescoço localmente avançado." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-12012009-162533/.

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INTRODUÇÃO: Osteopontina (OPN) é uma glicoproteína presente em tecidos e fluidos orgânicos e envolvida em vários processos patológicos que incluem inflamação, proliferação celular, invasão da matriz extracelular, progressão tumoral e metástase. Em pacientes (pts) portadores de carcinoma epidermóide de cabeça e pescoço (CECCP), OPN tem sido associada a uma maior agressividade tumoral e empregada como marcador prognóstico. Nós investigamos o valor prognóstico e preditivo da OPN sérica em pacientes portadores de CECCP tratados de forma uniforme. MÉTODOS: Estudo longitudinal prospectivo de 47 pts
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Pereira, Thiago de Almeida. "Participação da via do Hedgehog na fibrose hepática da esquistossomose mansoni humana e murina experimental." reponame:Repositório Institucional da FIOCRUZ, 2015. https://www.arca.fiocruz.br/handle/icict/14002.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2016-04-27T18:46:26Z No. of bitstreams: 1 Thiago Almeida Pereira. Participação...pdf: 128345460 bytes, checksum: 463e735ff04d1040b79e06171b01301e (MD5)<br>Approved for entry into archive by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2016-04-27T18:46:42Z (GMT) No. of bitstreams: 1 Thiago Almeida Pereira. Participação...pdf: 128345460 bytes, checksum: 463e735ff04d1040b79e06171b01301e (MD5)<br>Made available in DSpace on 2016-04-27T18:46:42Z (GMT). No. of bitstreams: 1 Thiago Almeida Pereira. Participação...pdf:
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Books on the topic "Osteoponten"

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Zohar, Ron. Intracellular osteopontin: Relationship to osteogenic differentiation and cell migration. University of Toronto, Faculty of Dentistry], 1998.

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Guo, Peirong. Immuno-scanning electron microscopy localization of osteopontin at remodelling sites in rat femora. National Library of Canada, 1996.

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Guo, Peirong. Immune-scanning electron microscopy localization of osteopontin at remodelling sites in rat femora. University of Toronto], 1996.

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T, Denhardt David, ed. Osteopontin: Role in cell signalling and adhesion. New York Academy of Sciences, 1995.

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Zhu, Baoqian. Characterization of a novel intracellular form of osteopontin. 2002.

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Cogan, Gabrielle. Expression of bone sialoprotein and osteopontin in breast cancer. 2003.

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Denhardt, David T. Osteopontin: Role in Cell Signalling and Adhesion (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1995.

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Butler, William T. Osteopontin: Role in Cell Signalling and Adhesion (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1995.

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Zhang, Qi. Isolation and characterization of porcine bone sialoproteins and the study of osteopontin (bone sialoprotein I) gene regulation. 1993.

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Ali-Fehmi, Rouba, and Eman Abdulfatah. Biological Aspects and Clinical Applications of Serum Biomarkers in Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0002.

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Ovarian cancer, the most aggressive gynecological malignancy, presents at advanced stages with metastatic disease. Diagnosis at an early stage is the most important determinant of survival; however, the majority of patients are asymptomatic at early stages and the current diagnostic tools used in clinics show limited success in early detection and hence the need for new diagnostic biomarkers. With the advance of techniques in genomic and proteomics, numerous biomarkers are emerging which may serve as a platform for early detection of ovarian cancer. These include gene-, protein-, miRNAs, and m
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Book chapters on the topic "Osteoponten"

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Allan, Alison L. "Osteopontin." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_4286.

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Holdenrieder, S. "Osteopontin." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_2322.

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Holdenrieder, S. "Osteopontin." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_2322-1.

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Allan, Alison L. "Osteopontin." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_4286-5.

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Allan, Alison L. "Osteopontin." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_4286.

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Bawage, Swapnil, Shannon E. Weeks, Lalita A. Shevde, and Rajeev S. Samant. "Osteopontin (Spp1)." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101771.

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Bawage, Swapnil, Shannon E. Weeks, Lalita A. Shevade, and Rajeev S. Samant. "Osteopontin (Spp1)." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101771-1.

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Graf, Kristof. "Osteopontin in Kardiomyozyten." In Bedeutung der Zell-Matrix-Interaktion für die linksventrikuläre Hypertrophie. Steinkopff, 2000. http://dx.doi.org/10.1007/978-3-642-93713-2_6.

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Graf, Kristof. "Osteopontin im menschlichen Herzen." In Bedeutung der Zell-Matrix-Interaktion für die linksventrikuläre Hypertrophie. Steinkopff, 2000. http://dx.doi.org/10.1007/978-3-642-93713-2_8.

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Graf, Kristof. "Osteopontin und linksventrikuläre Hypertrophie (Tiermodell)." In Bedeutung der Zell-Matrix-Interaktion für die linksventrikuläre Hypertrophie. Steinkopff, 2000. http://dx.doi.org/10.1007/978-3-642-93713-2_7.

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Conference papers on the topic "Osteoponten"

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Sorensen, Esben S. "STRUCTURAL STUDIES ON OSTEOPONTIN." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.273.

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Noda, Masaki. "OSTEOPONTIN FUNCTION IN BONE." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.332.

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Boskey, Adele L. "OSTEOPONTIN AND BIOMINERALIZATON: AN OVERVIEW." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.251.

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Zohar, Ron, Baoqian Zhu, Christopher A. G. McCulloch, and Jaro Sodek. "INTRACELLULAR OSTEOPONTIN AND CELL SURVIVAL." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.268.

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Singh, Krishna. "OSTEOPONTIN: ROLE IN MYOCARDIAL REMODELING." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.274.

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Tilli, Tatiana M., Kivvi Duarte De Mello, Maria Theresa Accioly, Paulo Antonio Faria, and Etel Rp Gimba. "Abstract 89: Osteopontin-c and osteopontin-b splicing isoforms activate prostate cancer progression features." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-89.

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Hampel, Dierk J., Victor I. Romanov, Susan R. Rittling, David T. Denhardt, and Michael S. Goligorsky. "MODE OF OSTEOPONTIN ACTION AS A SURVIVAL FACTOR: STUDY OF OSTEOPONTIN-DEFICIENT 3T3 FIBROBLASTS." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.301.

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Mello, Kivvi Duarte, Tatiana Martins Tilli, Ana Carolina S. Ferreira, Claudete Esteves Klumb, Luiz Eurico Nasciutti, and Etel Rodrigues Pereira Gimba. "Abstract 1346: Osteopontin-b and Osteopontin-c splicing isofoms activate prostate cancer cells prosurvival features." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1346.

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Rittling, Susan R., Brenda Bourassa, and Yanping Chen. "ROLE OF HOST OSTEOPONTIN IN TUMORIGENESIS." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.248.

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Kaartinen, Mari T., Sherif El-Maadawy, Niina H. Rasanen, Pekka H. Maenpaa, Janet Moradian-Oldak, and Marc D. McKee. "OSTEOPONTIN AS A SUBSTRATE FOR TRANSGLUTAMINASE." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.256.

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Reports on the topic "Osteoponten"

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Karcher, Elizabeth L., Donald C. Beitz, and Judith R. Stabel. Osteopontin Expression in Periparturient Dairy Cows Naturally Infected with Mycobacterium Avium Subsp. Paratuberculosis. Iowa State University, 2008. http://dx.doi.org/10.31274/ans_air-180814-843.

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Weber, George F. Contribution of the Receptor/Ligand Interaction Between CD44 and Osteopontin to Formation of Breast Cancer Metastases. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada384133.

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Weber, Georg. Contribution of the Receptor/Ligand Interaction Between CD44 and Osteopontin to Formation of Breast Cancer Metastases. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada393323.

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