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Journal articles on the topic 'Osteoporotic fractures'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lin, Xiaozhen, Yiji Li, Limei Wang, and Qiujiao Liao. "Current Status of Research on Anti-osteoporotic Drug Treatment and Compliance in Patients with Osteoporotic Fractures." Journal of Contemporary Medical Practice 6, no. 6 (2024): 7–11. http://dx.doi.org/10.53469/jcmp.2024.06(06).02.

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Osteoporotic Fracture (OPF), also known as fragility fracture, is a low-energy, non-violent fracture that commonly occurs in the elderly. Such fractures mostly occur in the thoracolumbar vertebral body, hip, distal radius and other parts, and are the main factors that cause osteoporosis patients to be hospitalized for diagnosis and treatment. Secondary fractures are prone to occur after fractures, and anti-osteoporotic treatment can effectively prevent further fractures in patients with osteoporotic fractures. Due to factors such as patients and their families’ insufficient understanding of th

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Ahn, Seong Hee, Seongbin Hong, Young J. Suh, et al. "ODP087 Dose-dependent effect of long-term statin use on risk of osteoporotic fracture in elderly patients." Journal of the Endocrine Society 6, Supplement_1 (2022): A162. http://dx.doi.org/10.1210/jendso/bvac150.331.

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Abstract Introduction Studies have been conducted to assess the association between the use of statin and risk of new onset osteoporosis or osteoporotic fractures, however, they have shown conflicting results. We aimed to investigate the association between statin use and the risk of major osteoporotic fractures in elderly population. Methods In this population cohort study with Korean National Health Insurance Service-Senior Cohort database, a total of 365,656 elderly (≥60 years) without previous history of osteoporosis were included. The patients who did not have a history of statin use in y

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Lyalina, V. V., I. A. Borshenko, S. V. Borisovskaya, et al. "Acute Osteoporotic Vertebral Fracture. Part 1. Definitions, Clinical Presentation, Pain Assessment, Diagnostic Imaging, Introduction to Differential Diagnosis." Russian Archives of Internal Medicine 12, no. 4 (2022): 254–66. http://dx.doi.org/10.20514/2226-6704-2022-12-4-254-266.

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Osteoporosis is a widespread metabolic disease of the skeleton among the elderly. Osteoporotic fractures are significant manifestation of the disease, which can substantially affect the quality of life. The purpose of this article is to review approaches to the management of patients with acute osteoporotic fracture. This article consists of two parts. The first part reviews general information about osteoporosis, clinical course of osteoporotic fracture, differential diagnosis of pain syndrome, methods of visualization of fractures, differential diagnosis of osteoporosis. In the second part,

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Lyalina, V. V., I. A. Borshenko, S. V. Borisovskaya, et al. "Acute Osteoporotic Vertebral Fracture. Part 2. Differential Diagnostics According to the Data of Imaging Methods. Conservative and Surgical Treatment." Russian Archives of Internal Medicine 12, no. 6 (2022): 438–49. http://dx.doi.org/10.20514/2226-6704-2022-12-6-438-449.

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Osteoporosis is a widespread metabolic disease of the skeleton among the elderly. Osteoporotic fractures are significant manifestation of the disease, which can substantially affect the quality of life. The purpose of this article is to review approaches to the management of patients with acute osteoporotic fracture. This article consists of two parts. The first part reviews general information about osteoporosis, clinical course of osteoporotic fracture, differential diagnosis of pain syndrome, methods of visualization of fractures, differential diagnosis of osteoporosis. In the second part,

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Watts, Nelson B. "Osteoporotic vertebral fractures." Neurosurgical Focus 10, no. 4 (2001): 1–3. http://dx.doi.org/10.3171/foc.2001.10.4.13.

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Osteoporosis is a significant public health problem. Vertebral fractures are the most common fracture in patients with osteoporosis, occurring in approximately 750,000 cases each year. The fractures may cause acute or chronic pain, reduce the quality of life, and shorten life expectancy. Several medications are available that reduce the risk of fracture. Vertebroplasty and kyphoplasty (balloon-inflated expansion of collapsed vertebrae followed by injection of bone cement) may reduce or relieve pain in selected patients. Although surgery is rarely necessary for the management of osteoporotic ve

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Romanov, G. N., N. F. Chernova, T. I. Moskvicheva, and E. V. Rudenko. "CLINICAL AND INSTRUMENTAL CHARACTERISTICS OF REPEATED OSTEOPOROTIC FRACTURES IN PATIENTS OF GOMEL REGION OF BELORUSSIA AND MODERN THERAPEUTIC STRATEGY." Osteoporosis and Bone Diseases 17, no. 2 (2014): 22–25. http://dx.doi.org/10.14341/osteo2014222-25.

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Introduction. Experienced osteoporotic fractures are a significant predictor of repeated, more severe fractures, entailing reduced quality of life and its expectancy. Objectives. To study the clinical and instrumental data of patients with single and repeated osteoporotic fractures of the forearm, proximal femur and spine, as well as the frequency of their occurrence in women of Gomel region of Belorussia. Materials and methods. The study included 2356 women aged over 50 years. Protocol included questionnaire with the assessment of detailed fracture data, medical history and Charlson comorbidi

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Oh, Ho-Seok, Sung-Kyu Kim, and Hyoung-Yeon Seo. "Characteristics of Osteoporosis & Osteoporotic Fractures in Korea Based on Health Insurance Review and Assessment (HIRA) Database: 2009–2017." Healthcare 9, no. 3 (2021): 324. http://dx.doi.org/10.3390/healthcare9030324.

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To investigate the incidence and characteristics of osteoporosis and osteoporotic fractures in Korea, we used the Health Insurance Review and Assessment Service (HIRA) database. Patients over 50 years old, who were diagnosed or treated for osteoporosis and osteoporotic fractures in all hospitals and clinics, were analyzed between 1 January 2009 and 31 December 2017 by using the HIRA database that contains prescription data and diagnostic codes. These data were retrospectively analyzed by decade and age-specific and gender-specific incidents in each year. We also evaluated other characteristics

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Parathan, S., and T. Gobyshanger. "Pattern of second osteoporotic fractures. A descriptive study in two tertiary care centers in Sri Lanka." Sri Lankan Journal of Orthopaedic Surgery 8, no. 1 (2022): 41–53. http://dx.doi.org/10.4038/tsljos.v8i1.7.

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Introduction: Second osteoporotic fractures have higher morbidity and mortality than prior osteoporotic fractures. Materials and methods: A retrospective case series of patients admitted to two tertiary care hospitals with second osteoporotic fractures from April 2020 to March 2021 assessed demography, time since the first osteoporotic fracture, fracture locations, comorbidities, menopausal age, predisposing drugs and habits, parental history, fall risk, BMI, family support and treatment. Results: Fifty-four patients were studied. Forty-nine (90.7%) were females, Mean age was 75.8

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Wang, Yu-Ming, and Ping Yi. "Global current research status and future hotspots in osteoporotic fracture based on bibliometric assessment and visualization techniques." World Journal of Clinical Cases 12, no. 19 (2024): 3908–17. http://dx.doi.org/10.12998/wjcc.v12.i19.3908.

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BACKGROUND In the past decade, the evolution of themes in the field of osteoporotic fractures has changed from epidemiology and prediction of long-term morbidity, risk assessment of osteoporotic fractures, and zoledronic acid and denosumab in the treatment of osteoporosis to treatment guidelines for osteoporosis and the side effects caused by anti-osteoporotic drugs. AIM To understand the trends and hotspots in osteoporotic fracture research. METHODS Original articles were retrieved between January 1, 2010, and December 31, 2019, from the Web of Science Core Collection database. CiteSpace soft

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Etibarlı, S. S., R. S. Khalilzadeh, C. N. Iskanderov, and E. S. Hajıyev. "THE PREVALENCE AND INCIDENCE OF OSTEOPOROTIC VERTEBRAL FRACTURES." National Journal of Neurology 1, no. 24 (2024): 18–22. https://doi.org/10.61788/njn.v1i24.02.

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Osteoporosis is a skeletal disorder characterized by low bone mass and deterioration of bone tissue with a consequent increase in the fragility of bone and hence susceptibility to fracture. An osteoporotic fracture occurs as a result of fragility of the vertebrae. Acquaintance with the science of osteoporosis and osteoporotic fractures, new hypotheses, theories, classifications, variants, and its comparative analysis in people of different genetic backgrounds in different countries leads to a deeper understanding of the problem. Scientists from different countries of the world have made great

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Povoroznyuk, V. V., H. Johansson, N. V. Grygorieva, et al. "Ukrainian FRAX version in the male osteoporosis management." PAIN, JOINTS, SPINE 11, no. 2 (2021): 53–61. http://dx.doi.org/10.22141/2224-1507.11.2.2021.236563.

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Background. At present, FRAX is a well-known and widely-used risk assessment tool for major osteoporotic fractures. The Ukrainian version of the FRAX algorithm was presented in 2016; with the “intervention threshold” for additional DXA examination and antiosteoporotic treatment of the Ukrainian women published in 2019. However, the data on its possible uses in men are limited. The purpose of the study was to evaluate the possibilities of using the previously developed criteria of the Ukrainian FRAX algorithm in Ukrainian men. Materials and methods. We examined 653 outpatients aged 40–88 yea

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Möckel, Luis. "Number and Impact of Osteoporotic Forearm Fractures: An Analysis of German Hospital Data." Osteologie 29, no. 02 (2020): 150–56. http://dx.doi.org/10.1055/a-1023-4859.

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Abstract Introduction Osteoporosis is a burden for Germany, however recent data on osteoporotic forearm fractures is missing. Methods Numbers of hospital diagnosed forearm fractures based on ICD-10 code S52.- for 2000 to 2017 were taken from GBE database. From this dataset, number of osteoporotic forearm fractures in patients aged 50+ years were calculated using age- and gender specific weighting factors. In addition, fracture rates per 100,000 people, total days in hospital and quality-adjusted life years (QALYs) lost due to osteoporotic forearm fractures were calculated. Results In 2017, a t

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Belova, K. Yu, O. B. Yershova, A. A. Degtyarev, M. V. Belov, V. O. Gerasimov, and S. Yu Fedotov. "REFRACTURE PREVENTION SYSTEM: FIRST RESULTS OF A PILOT PROGRAM WITHIN THE PROJECT «PROMETHEUS» IN YAROSLAVL." Osteoporosis and Bone Diseases 17, no. 2 (2014): 3–6. http://dx.doi.org/10.14341/osteo201423-6.

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In order to reduce the incidence of recurrent fractures in patients that had already experienced low-energy (osteoporotic) fracture, the International Osteoporosis Foundation initiated the program «Capture the fracture». Established Best Practice Framework represents 13 standards to evaluate the effectiveness of the centers for the prevention of recurrent fractures, organized in different countries. In 2012 the Russian Association on Osteoporosis started the project PROMETHEUS [Creation the system to prevent recurrence of fractures in patients with osteoporosis]. In order to implement this pro

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Mok, Chi Chiu, Sau Mei Tse, Kar Li Chan, and Ling Yin Ho. "Estimation of fracture risk by the FRAX tool in patients with systemic lupus erythematosus: a 10-year longitudinal validation study." Therapeutic Advances in Musculoskeletal Disease 14 (January 2022): 1759720X2210744. http://dx.doi.org/10.1177/1759720x221074451.

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Background: The fracture risk assessment tool has been widely used to stratify the 10-year fracture risk to guide therapy. Using the actual fracture data of a 10-year longitudinal cohort of older patients with systemic lupus erythematosus, we reported an underestimation of the tool in predicting major symptomatic osteoporotic fractures. Treatment of osteoporosis in systemic lupus erythematosus should not be based on fracture risk estimation alone. Relevant time-dependent risk factors should be taken into account for an individualized decision. Objective: To compare the observed fracture incide

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Kim, Dongyeop, Jee Hyun Kim, Heajung Lee, Iksun Hong, Yoonkyung Chang, and Tae-Jin Song. "Association of gamma-glutamyl transferase variability with risk of osteoporotic fractures: A nationwide cohort study." PLOS ONE 18, no. 6 (2023): e0277452. http://dx.doi.org/10.1371/journal.pone.0277452.

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Objectives Gamma-glutamyl transferase (GGT) is related to inflammation, osteoporosis, and vascular diseases. Recently, changes in metabolic parameters have been proposed as osteoporosis biomarkers. We aimed to assess longitudinally the association of GGT variability with osteoporotic fractures. Methods From the National Health Insurance Service-Health Screening Cohort database, participants who underwent three or more health examinations between 2003 and 2008 were included (n = 1,072,432). Variability indexes were as follows: (1) coefficient of variation (CV), (2) standard deviation (SD), and

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Czerwiński, Edward, Jarosław Czubak, Marek Synder, Maja Warzecha, and Małgorzata Berwecka. "Contemporary Management of Osteoporotic Fractures." Ortopedia Traumatologia Rehabilitacja 20, no. 2 (2018): 91–102. http://dx.doi.org/10.5604/01.3001.0011.7665.

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With aging of the population, osteoporotic fractures are becoming an increasing medical problem worldwide. It has been estimated that 2,700,000 patients experienced a low energy fracture in the Polish population in 2010. On the basis of contemporary world standards and publications in the field of orthopaedics and traumatic surgery, a summary of the principles of management of osteoporotic fractures is presented. Both general problems of fracture treatment in elderly patients as well as difficulties in surgical and conservative treatment resulting from osteoporotic bone abnormalities are dis

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Kerschan-Schindl, K., M. Hackl, E. Boschitsch, et al. "Diagnostic Performance of a Panel of miRNAs (OsteomiR) for Osteoporosis in a Cohort of Postmenopausal Women." Calcified Tissue International 108, no. 6 (2021): 725–37. http://dx.doi.org/10.1007/s00223-020-00802-3.

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AbstractA specific signature of 19 circulating miRNAs (osteomiRs) has been reported to be associated with fragility fractures due to postmenopausal osteoporosis. However, it is unknown whether osteoporotic fractures or low BMD phenotypes are independently contributing to changes in osteomiR serum levels. The first aim was to characterize the abundance, sensitivity to hemolysis, and correlation of osteomiR serum levels, the second objective to evaluate the diagnostic accuracy of osteomiRs for osteoporosis according to the WHO criteria and on basis of major osteoporotic fracture history. Fifty p

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Fazal, Farheen, Haider Zaman, Aiman Ali Khan, et al. "FRAX (FRACTURE RISK ASSESSMENT TOOL) PREDICTION WITHOUT BMD (BONE MINERAL DENSITY) FOR ASSESSMENT OF OSTEOPOROTIC FRACTURE RISK IN THE GENERAL POPULATION OF PESHAWAR." Journal of Medical Sciences 33, no. 2 (2025): 67–71. https://doi.org/10.52764/jms.25.33.2.2.

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Objective: To identify fracture risk assessment without using bone mineral density in assessing osteoporotic fracture risk using a FRAX prediction model among the general population of Peshawar. Materials and Methods: A descriptive cross-sectional study was conducted from January to June 2024 among adults aged 40 and older residing in Peshawar. A sample of 240 was selected through a multistage sampling technique. Inclusion criteria were those who were residents in Peshawar and were willing to participate, and those having chronic illnesses like liver disease, cancer, or kidney disease were exc

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Marchenkova, L. "POS1469-HPR THE ASSESSMENT OF FRACTURE RISK AND OSTEOPOROSIS RATE AMONG PATIENTS OVER 50 YEARS OLD UNDERGOING MEDICAL REHABILITATION." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1020.2–1020. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4258.

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Background:Taking a course of physical rehabilitation creates the prerequisites for falls and injuries in patients at high risk of fractures. Data on fracture risk and prevalence of osteoporosis in older patients starting medical rehabilitation can change the approach of doctors to the development of rehabilitation programs and the management of such patients.Objectives:To assess the prevalence of osteoporosis, individual risk factors for osteoporosis as well as the proportion of people with high risk of osteoporotic low-energy fractures among patients over 50 years old undergoing treatment ac

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Tile, Lianne, and Angela M. Cheung. "Atypical femur fractures: current understanding and approach to management." Therapeutic Advances in Musculoskeletal Disease 12 (January 2020): 1759720X2091698. http://dx.doi.org/10.1177/1759720x20916983.

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Osteoporosis and resulting osteoporotic fractures are responsible for significant morbidity, excess mortality, and health care costs in the developed world. Medical therapy for osteoporosis has been shown in multiple randomized controlled trials to reduce the risk of vertebral and non-vertebral fractures and hip fractures, and in some studies bisphosphonate medications have been associated with improved survival. Although the overall benefit to risk ratio of osteoporosis medications remains favorable, there have been concerns raised about the long-term safety of these treatments. Atypical femu

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Wysocki, Matthew A., and Scott T. Doyle. "Advancing Osteoporosis Evaluation Procedures: Detailed Computational Analysis of Regional Structural Vulnerabilities in Osteoporotic Bone." Journal of Personalized Medicine 13, no. 2 (2023): 321. http://dx.doi.org/10.3390/jpm13020321.

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Osteoporotic fractures of the femur are associated with poor healing, disability, reduced quality of life, and high mortality rates within 1 year. Moreover, osteoporotic fractures of the femur are still considered to be an unsolved problem in orthopedic surgery. In order to more effectively identify osteoporosis-related fracture risk and develop advanced treatment approaches for femur fractures, it is necessary to acquire a greater understanding of how osteoporosis alters the diaphyseal structure and biomechanical characteristics. The current investigation uses computational analyses to compre

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Pai, Yuan-Yi, Jiaan-Der Wang, Hsin-En Ho, et al. "Risk of Fractures, Repeated Fractures and Osteoporotic Fractures among Patients with Hemophilia in Taiwan: A 14-Year Population-Based Cohort Study." International Journal of Environmental Research and Public Health 20, no. 1 (2022): 525. http://dx.doi.org/10.3390/ijerph20010525.

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The world is aging, and hemophilia patients are as well. The association between patients with hemophilia (PWH) and low bone mineral density is clear. However, the incidence of fractures in patients with hemophilia is inconclusive, and no research has yet explored repeated fractures among PWH. In this study, we investigated the incidence of all-site fractures, repeated fractures and osteoporotic fractures amongst PWH. The study compared the incidence of all-site fractures, repeated fractures and osteoporotic fractures occurring in all PWH who were enrolled in Taiwan’s National Health Insurance

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Issayeva, Samal M., Olga M. Lesnyak, Bakytsholpan G. Issayeva, Dina S. Dilmanova, Meruyert A. Bissembay, and Gaukhar A. Burakhanova. "Comparative analysis of risk factors for hip fracture in patients of different nationalities living in Kazakhstan." Russian Family Doctor 26, no. 2 (2022): 13–22. http://dx.doi.org/10.17816/rfd108304.

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BACKGROUND: Osteoporosis is a multifactorial systemic skeletal disease characterized by a decrease in bone strength leading to an increased risk of fractures. Hip fracture is a serious complication of osteoporosis. It is expected in Kazakhstan by 2050 the annual number of hip fracture will increase by 140% compared to 2015 data and will amount to 28,048 cases. There are differences in the incidence of fractures and low bone mineral density in different ethnic groups. However, low bone mineral density is only one of many risk factors for osteoporotic fractures. AIM: To study the risk fact

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Muratore, Maurizio, Francesco Conversano, Maria Daniela Renna, Paola Pisani, Valeria Villani, and Sergio Casciaro. "Social Impact of Osteoporotic Fractures." International Journal of Measurement Technologies and Instrumentation Engineering 4, no. 2 (2014): 39–53. http://dx.doi.org/10.4018/ijmtie.2014040104.

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Osteoporosis affects about 200 million subjects in the world and is responsible for 8.9 million fractures each year. The frequency of osteoporotic fractures is rising in many countries, due to the increased longevity of the population. In Europe, the annual cost of all osteoporotic fractures has been estimated to be 30 billion of Euros. In this paper, after an overview of the socioeconomic impact of osteoporosis in the world and in Italy, with particular focus on Apulia region, the most important techniques used to assess the fracture risk are briefly described. Moreover, the most commonly use

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Hollensteiner, Marianne, Sabrina Sandriesser, Emily Bliven, Christian von Rüden, and Peter Augat. "Biomechanics of Osteoporotic Fracture Fixation." Current Osteoporosis Reports 17, no. 6 (2019): 363–74. http://dx.doi.org/10.1007/s11914-019-00535-9.

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Abstract Purpose of Review Fractures of osteoporotic bone in elderly individuals need special attention. This manuscript reviews the current strategies to provide sufficient fracture fixation stability with a particular focus on fractures that frequently occur in elderly individuals with osteoporosis and require full load-bearing capacity, i.e., pelvis, hip, ankle, and peri-implant fractures. Recent Findings Elderly individuals benefit immensely from immediate mobilization after fracture and thus require stable fracture fixation that allows immediate post-operative weight-bearing. However, ost

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Abishev, Nurzhan. "Surgical Treatment of a Fracture of the Lumbar Spine Associated with Systemic Osteoporosis. Clinical case." Traumatology and Orthopаedics of Kazakhstan 64, no. 3 (2022): 29–34. http://dx.doi.org/10.52889/1684-9280-2022-3-64-29-34.

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Fractures in osteoporosis are typically for all bones of skeleton, except for cranial bones. Most often, fractures of bodies of the thoracic and lumbar vertebrae, carpal bones and femoral bone are developed. Osteoporosis is the fourth among the most common diseases leading to disability, after diseases of the cardiovascular system, diabetes mellitus, and oncological neoplasms.Hybrid stabilization is a common surgical strategy for unstable osteoporotic fractures of thoracolumbar vertebrae, leading to good clinical outcomes in most patients.This article describes an experience of successful surg

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Xu, Jixi, Mingbo Li, Wei Pei, et al. "Reduced Circulating Levels of miR-491-5p and miR-485-3p Are Associated with the Occurrence of Vertebral Fractures in Postmenopausal Women with Osteoporosis." Genetics Research 2022 (March 7, 2022): 1–8. http://dx.doi.org/10.1155/2022/3838126.

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Objective. Postmenopausal women experiences osteoporotic structural damage and bone fragility resulting from reduced bone formation and increased bone resorption. Osteoporosis frequently affects the vertebral column and causes compression fractures. This study aims to characterize roles of miRNAs in osteoporosis and subsequent incidence risk of vertebral fractures for postmenopausal women. Methods. Differentially expressed miRNAs between osteoporotic patients with vertebral fractures and osteoporotic patients without fracture were identified. This retrospective study included 78 osteoporotic p

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Dionyssiotis, Yannis, Grigorios Skarantavos, and Panayiotis Papagelopoulos. "Modern Rehabilitation in Osteoporosis, Falls, and Fractures." Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 7 (January 2014): CMAMD.S14077. http://dx.doi.org/10.4137/cmamd.s14077.

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In prevention and management of osteoporosis, modern rehabilitation should focus on how to increase muscular and bone strength. Resistance exercises are beneficial for muscle and bone strength, and weight-bearing exercises help maintain fitness and bone mass. In subjects at higher risk for osteoporotic fractures, particular attention should be paid to improving balance – the most important element in falls prevention. Given the close interaction between osteoporosis and falls, prevention of fractures should be based on factors related to bone strength and risk factors for falls. Fractures are

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Abdel-Wanis, Mohamed El-Sayed, Mohamed Tharwat Mahmoud Solyman, and Nahla Mohamed Ali Hasan. "MRI PATTERN OF VERTEBRAL FRACTURES DUE TO OSTEOPOROSIS, INFECTION, AND MALIGNANT TUMORS." Journal of Musculoskeletal Research 13, no. 02 (2010): 57–63. http://dx.doi.org/10.1142/s0218957710002491.

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No previous studies discussed the significance of the MRI pattern of vertebral collapse in differentiation between vertebral compression fractures due to malignancy, osteoporosis, and infections. MRI was used in the evaluation of 152 atraumatic vertebral compression fractures in 80 patients: 85 malignant, 34 osteoporotic, and 33 infective. Central collapse of the fractured vertebral body was the commonest pattern in malignant fractures (57 vertebrae, 67%), followed by uniform collapse (21 vertebrae, 24.7%), then anterior wedging (5 vertebrae, 5.9%), and finally posterior wedging (2 vertebrae,

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Larsson, S. "Treatment of Osteoporotic Fractures." Scandinavian Journal of Surgery 91, no. 2 (2002): 140–46. http://dx.doi.org/10.1177/145749690209100202.

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Fractures are the most common problem associated with osteoporosis and despite advances in prevention and treatment of osteoporosis the number of fractures continue to increase. Along with the three classic locations hip, spine and wrist, there are several other fractures that commonly are related to osteoporosis. The weak bone makes it difficult to achieve a stable bone-implant construct and general weakness of the patient often prevents reduction of load on the injured extremity during healing. The main treatment goal should be preservation of function even at the expense of restoration of e

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Murillo, Bernardo, Christian Antonio Allende Nores, and Orlando Rodríguez. "Incidencia de diagnóstico y tratamiento de la osteoporosis en pacientes con fractura de radio distal. [Diagnosis and treatment incidence of osteoporosis in patients with distal radius fractures]." Revista de la Asociación Argentina de Ortopedia y Traumatología 84, no. 2 (2019): 99–104. http://dx.doi.org/10.15417/issn.1852-7434.2019.84.2.664.

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Introducción: Las fracturas de radio distal en pacientes mayores son un indicador de osteoporosis. El objetivo de este estudio fue determinar el diagnóstico y el tratamiento de la osteoporosis en pacientes con fractura de radio distal, operados en nuestra institución, entre 2012 y 2014.Materiales y Métodos: Los datos se obtuvieron de entrevistas telefónicas a 41 pacientes mayores, operados por fracturas de radio distal. Las variables evaluadas fueron: sexo, edad, enfermedades asociadas, tabaquismo, fracturas previas, tratamiento antiosteoporótico previo o posterior a la fractura en cuestión, e

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Zhou, Hongfa, Jinyuan Chen, Xuan Zhang, et al. "Exploring the Application of Graphene Oxide-Based Nanomaterials in the Repair of Osteoporotic Fractures." Nanomaterials 14, no. 6 (2024): 553. http://dx.doi.org/10.3390/nano14060553.

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Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing osteoporotic fractures. It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages in tissue engineering due to their excellent biocompatibility, mechanical properties, and osteoinductive abilities. Based on that, GO-nanocomp

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Nowakowska-Płaza, Anna, Jakub Wroński, Iwona Sudoł-Szopińska, and Piotr Głuszko. "Clinical Utility of Trabecular Bone Score (TBS) in Fracture Risk Assessment of Patients with Rheumatic Diseases Treated with Glucocorticoids." Hormone and Metabolic Research 53, no. 08 (2021): 499–503. http://dx.doi.org/10.1055/a-1528-7261.

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AbstractChronic glucocorticoid therapy is associated with osteoporosis and can cause fractures in up to 50% of patients. Increased risk of fractures in patients with glucocorticoid-induced osteoporosis does not result only from the decreased bone mineral density (BMD) but also bone microarchitecture deterioration. Trabecular bone score (TBS) is a method complementary to DXA, providing additional information about trabecular bone structure. The aim of this study was to assess the clinical utility of TBS in fracture risk assessment of patients treated with glucocorticoids. Patients with rheumati

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Jehn, Ulrich, Anja Kortenhorn, Katharina Schütte-Nütgen, et al. "The Influence of Parathyroidectomy on Osteoporotic Fractures in Kidney Transplant Recipients: Results from a Retrospective Single-Center Trial." Journal of Clinical Medicine 11, no. 3 (2022): 654. http://dx.doi.org/10.3390/jcm11030654.

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Kidney transplant (KTx) recipients are a high-risk population for osteoporotic fractures. We herein aim to identify the role of pre-transplant parathyroidectomy (PTX) and other modifiable factors associated with osteoporotic fractures in KTx recipients. We conducted a retrospective study involving 711 adult patients (4608 patient-years) who were transplanted at our center between January 2007 and June 2015. Clinical data were extracted from patients’ electronic medical records. Different laboratory and clinical parameters for mineral bone disease (MBD) and osteoporosis, including medication, w

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Ning, Shenghua, Yushan Guo, Jinsheng Cai, et al. "Effects of kidney nourishing and bone strengthening decoction on re-fracture after percutaneous vertebral augmentation in osteoporotic compression fractures." Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 24, no. 3 (2025): 354–67. https://doi.org/10.37360/blacpma.25.24.3.26.

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Kidney Nourishing and Bone Strengthening Decoction, a traditional Chinese herbal formula, has been known for its role in regulating bone metabolism and enhancing bone density (BD). Osteoporotic compression fractures are common clinical complications in patients with osteoporosis, and percutaneous vertebral augmentation is a commonlyused treatment method. This work aimed to investigate the preventive effect of the Kidney Nourishing and Bone Strengthening Decoction combined with conventional Western medicine treatment on the occurrence of vertebral re-fracture after percutaneous vertebral augmen

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Choi, Sang, Seong-Ryul Kwon, Ju-Yang Jung, et al. "Prevalence and Fracture Risk of Osteoporosis in Patients with Rheumatoid Arthritis: A Multicenter Comparative Study of the FRAX and WHO Criteria." Journal of Clinical Medicine 7, no. 12 (2018): 507. http://dx.doi.org/10.3390/jcm7120507.

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(1) Background: We evaluated the prevalence and fracture risk of osteoporosis in patients with rheumatoid arthritis (RA), and compared the fracture risk assessment tool (FRAX) criteria and bone mineral density (BMD) criteria established by the World Health Organization (WHO). (2) Methods: This retrospective cross-sectional study, which included 479 RA patients in 5 hospitals, was conducted between January 2012 and December 2016. The FRAX criteria for high-risk osteoporotic fractures were calculated including and excluding the BMD values, respectively. The definition of high risk for fracture b

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Lems, Willem F., and Hennie G. Raterman. "Critical issues and current challenges in osteoporosis and fracture prevention. An overview of unmet needs." Therapeutic Advances in Musculoskeletal Disease 9, no. 12 (2017): 299–316. http://dx.doi.org/10.1177/1759720x17732562.

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Osteoporosis is a silent disease with increasing prevalence due to the global ageing population. Decreased bone strength and bone quality is the hallmark of osteoporosis which leads to an increased risk of fragility fractures in elderly. It has been estimated that approximately ~50% of women will suffer during their lifetime from an osteoporotic fracture. This must be considered as a major health concern, as it has previously been established that fragility fracture has been associated with decreased quality of life due to increased disability, more frequent hospital admission and most importa

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Kwon, Mi Jung, Jae Yong Park, Sung Gyun Kim, et al. "Potential Association of Osteoporosis and Not Osteoporotic Fractures in Patients with Gout: A Longitudinal Follow-Up Study." Nutrients 15, no. 1 (2022): 134. http://dx.doi.org/10.3390/nu15010134.

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Health issues associated with gout and increased occurrence of osteoporosis or fractures have been raised; however, the results are elusive. Herein, we explored the possible link between gout and incident osteoporosis/osteoporotic fractures based on long-term follow-up nationwide data. This study enrolled 16,305 patients with gout and 65,220 controls who were matched by propensity score at a 1:4 ratio on the basis of sex, age, income, and residence from the Korean National Health Insurance Service-Health Screening Cohort database (2002–2015). A Cox proportional hazard model was employed to ide

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Thành Toàn, Võ, Đặng Phan Vĩnh Toàn та Nguyễn Trọng Sỹ. "ĐÁNH GIÁ THỜI GIAN LIỀN XƯƠNG SAU PHẪU THUẬT KẾT HỢP XƯƠNG Ở BỆNH NHÂN GÃY XƯƠNG CÓ LOÃNG XƯƠNG". Tạp chí Sức khỏe và Lão hóa 1, № 1 (2025): 52–56. https://doi.org/10.63947/bvtn.v1i1.7.

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To evaluate the impact of osteoporosis on bone union time. The study involved 405 fracture patients divided into two groups: Group A, consisting of 242 patients with fractures and osteoporosis; and Group B, consisting of 163 patients with corresponding fractures but without osteoporosis, from January 2020 to January 2024. The osteoporotic patient group was older, with a majority being female (p < 0.05). The most common fracture type was intertrochanteric, with 81 cases accounting for 20% of all fractures. Of these, the majority were in patients with osteoporosis (52 patients, 64.2%). Osteop

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Binkley, Neil. "Osteoporosis in men." Arquivos Brasileiros de Endocrinologia & Metabologia 50, no. 4 (2006): 764–74. http://dx.doi.org/10.1590/s0004-27302006000400021.

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Osteoporosis is defined as "a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture". Approximately 4050% of women sustain osteoporotic fractures in their lifetime; as such, it is appropriate that studies initially focused upon females. Despite an increased recognition of osteoporotic fractures in men, there continues to be neglect of this disease in males. This ongoing neglect is inappropriate as 2533% of men in some populations will sustain osteoporotic fractures

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Link, Thomas M. "Radiology of Osteoporosis." Canadian Association of Radiologists Journal 67, no. 1 (2016): 28–40. http://dx.doi.org/10.1016/j.carj.2015.02.002.

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The radiologist has a number of roles not only in diagnosing but also in treating osteoporosis. Radiologists diagnose fragility fractures with all imaging modalities, which includes magnetic resonance imaging (MRI) demonstrating radiologically occult insufficiency fractures, but also lateral chest radiographs showing asymptomatic vertebral fractures. In particular MRI fragility fractures may have a nonspecific appearance and the radiologists needs to be familiar with the typical locations and findings, to differentiate these fractures from neoplastic lesions. It should be noted that radiologis

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Kim, Hyojune, Wonhee Lee, SeungHyun Choi, et al. "Role of Additional Inferomedial Supporting Screws in Osteoporotic 3-Part Proximal Humerus Fracture: Finite Element Analysis." Geriatric Orthopaedic Surgery & Rehabilitation 11 (January 1, 2020): 215145932095695. http://dx.doi.org/10.1177/2151459320956958.

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Introduction: Importance of inferomedial supporting screws in preventing varus collapse has been investigated for the proximal humerus fracture. However, few studies reported the results of osteoporotic complex fracture. This study aimed to demonstrate the stress distribution pattern, particularly in osteoporotic 3-part proximal humerus fractures involving greater tuberosity (GT) with different screw configurations. Materials and methods: Using the computed tomography (CT) images of 2 patients, who had osteoporosis and the other had normal bone density, 3-part fractures involving the GT, witho

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Laffaire, M., M. Caroline, E. Allado, E. Bauer, I. Chary Valckenaere, and D. Loeuille. "AB0948 Osteoporotic screening and prevalence of severe osteoporotic fractures in a population of psoriatic arthritis initiating a biologic treatment." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1602.2–1603. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3871.

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BackgroundOsteoporosis is a common complication of Rheumatic diseases. The association between osteoporosis and rheumatoid arthritis is clearly demonstrated while this association is still debated as well as for the screening of osteoporosis by Dual-Energy X-Ray Absorptiometry (DEXA) or to demonstrate an increased risk of fracture on radiography in a population of Psoriatic Arthritis (PsA). The prevalence of fragility fractures reported on medical reports ranged between 12% and 40% in PsA patients. Only a few studies evaluated the prevalence of vertebral fracture (VF) on spine radiographs. To

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Kozhevnikova, P., P. Kovalenko, S. Glukhova, I. Dydykina, and A. Lila. "POS1108 THE ACCURACY OF OSTEOPOROTIC FRACTURE RISK PREDICTION IN PATIENTS WITH RHEUMATOID ARTHRITIS USING THE PREDICTIVE MODEL DEVELOPED AT V.A. NASONOVA REASEARCH INSTITUTE OF RHEUMATOLOGY (RUSSIA) AND FRACTURE RISK ASSESSMENT TOOL (FRAX)." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 834.2–835. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1717.

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Background:FRAX is a computer-based algorithm that calculates the 10-year probability of a major osteoporotic fracture and the 10-year probability of hip fracture. However, FRAX has several limitations in assessing the risk of fracture in patients with rheumatoid arthritis (RA).In 2013 V.A. Nasonova Reasearch Institute of Rheumatology (Russia) developed a predictive mathematical model for assessing the risk of osteoporotic fractures in RA, which includes 2 main risk factors: cumulative glucocorticoid dose (GC), decrease in BMD in the femoral neck to osteoporosis, and 2 additional factors: for

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Zamboni, Caio, Marina Sousa Carvalho, Eduardo Araujo Pires, Jorge Rafael Durigan, Patrícia Maria de Moraes Barros Fucs, and Marcelo Tomanik Mercadante. "ARE TRAUMATOLOGISTS TREATING OSTEOPOROSIS TO PREVENT NEW FRACTURES IN BRAZIL?" Acta Ortopédica Brasileira 26, no. 6 (2018): 384–87. http://dx.doi.org/10.1590/1413-785220182606202125.

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ABSTRACT Objectives: To determine the proportion of traumatologists who investigate osteoporosis in elderly patients with fractures and recommend secondary prevention of osteoporotic fractures. Methods: We distributed questionnaires to 244 physicians attending the 2015 Brazilian Congress of Orthopedic Trauma. We determined the respondents’ profiles and assessed how they investigated and treated osteoporosis in elderly patients with fractures. Results: Overall, 32% of the respondents reported that their knowledge level regarding osteoporosis ranged from 0-5 (out of 0-10). In total, 42% of the p

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Olarte, Carlos M., Ana M. López, Jonathan Tihanyi Feldman, et al. "Impact of a Secondary Prevention Program for Fragility Fractures at the Orthogeriatric Clinical Care Center at the Fundación Santa Fe de Bogotá, 2014-2020." Geriatric Orthopaedic Surgery & Rehabilitation 13 (January 2022): 215145932211181. http://dx.doi.org/10.1177/21514593221118182.

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Introduction: The presence of a fragility fracture increases the risk of new fractures. The timely and prompt initiation of treatment for osteoporosis can reduce the incidence of new fractures, for which adherence to management is a determining factor. The main objective of the study was to characterize the secondary prevention program for fragility hip fractures in patients older than 65 years, determine adherence to treatment and its effect on the appearance of new fractures in the established follow-up period. Materials and Methods: A descriptive retrospective cohort study was carried out.

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Azibte, Gebeyehu, Theodros Aberra, Zekarias Ayalew, et al. "Risk Factors for Ten-Year Risk of Osteoporosis in Type 2 DM Patients Attending Tikur Anbessa Specialized Hospital Diabetic Center Cross-sectional Study." International Journal of Diabetes and Endocrinology 9, no. 2 (2024): 46–55. http://dx.doi.org/10.11648/j.ijde.20240902.13.

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&lt;i&gt;Background&lt;/i&gt;: Type 2 diabetes mellitus (T2DM) is a major contributing factor to osteoporotic fractures via different mechanisms. This study assessed the ten-year risk of osteoporosis and associated factors for osteoporotic fractures in T2DM patients. &lt;i&gt;Methods&lt;/i&gt;: Data from 175 type diabetes mellites (T2DM) patients over 40 years attending a diabetes clinic at Tikur Anbessa Specialized Hospital (TASH) were collected. Demographic information, diabetic complications, blood sugar levels, and other medical illnesses were collected by a

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Jang, Min Uk, Young-Min Kwon, Jihyun Hwang, et al. "Analysis of Preventive Effect of Bisphosphonate for Osteoporotic Fracture in Patients with Alzheimer’s Disease and Patient Mortality." Journal of Clinical Medicine 14, no. 2 (2025): 300. https://doi.org/10.3390/jcm14020300.

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Background: Alzheimer’s disease (AD) is the most common neurodegenerative disease in the older adult population and is often associated with reduced physical activity. Reduced activity and mechanical loading subsequently reduce bone mineral density and increase risk of osteoporosis. Bisphosphonates (BPs) offer preventative effects on osteoporotic fractures in the general population, but their effects on patients with AD are less known. This study aimed to assess the impact of BPs on osteoporotic fractures and survival in patients with AD. Methods: In this nationwide retrospective cohort study,

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Baccichetti, A., P. L. Nguyen-Thi, A. Blum, et al. "SAT0459 EVALUATION OF THE PREVALENCE AND THE MANAGEMENT OF OSTEOPOROTIC FRACTURES IN PATIENTS HOSPITALIZED AT NANCY UNIVERSITY HOSPITAL (FRANCE) IN 2017." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1187.1–1187. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3366.

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Background:Osteoporotic fractures are a major public health concern because of their consequences in morbidity, costs and mortality. In the meantime, historically postfracture osteoporosis medication use rates have been poor.Objectives:The aim is to analyze the management of osteoporosis in patients hospitalized for osteoporotic fractures (OF) at Nancy University Hospital (France) in 2017.Methods:Total number of hospitalized patients and hospital stays were extracted by the Department of Medical Information (DIM) which selected departments with at least forty hospitalizations with Medical Unit

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Sonnabend, Hajerah, Vishnu Priya Pulipati, Sanford Baim, Todd Beck, Ethan M. Ritz, and J. Alan Simmons. "Fracture Rates in Men With Non-Metastatic Prostate Cancer on Androgen Deprivation Therapy With or Without Anti-Osteoporosis Treatment." Journal of the Endocrine Society 5, Supplement_1 (2021): A246—A247. http://dx.doi.org/10.1210/jendso/bvab048.501.

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Abstract Introduction: Androgen deprivation therapy (ADT) decreases bone mineral density and increases osteoporotic fracture (OsteoFx) risk. Hypothesis: To assess OsteoFx incidence most predictive of future OsteoFx among men with prostate cancer on ADT. Methods: 4370 electronic medical records were reviewed of adult men with prostate cancer on cancer therapy +/- anti-osteoporotic therapy (Anti-OsteoRx) from 2011–2019. Cancer therapy included ADT (anti-androgens, GnRH agonists & antagonists, orchiectomy) and supplemental cancer therapy (SupplRx) (prostatectomy, brachytherapy, radiation, imm

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