Academic literature on the topic 'OTKO'

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Journal articles on the topic "OTKO"

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Michelini, Lisete C., Marialuisa C. Marcelo, Janet Amico, and Mariana Morris. "Oxytocinergic regulation of cardiovascular function: studies in oxytocin-deficient mice." American Journal of Physiology-Heart and Circulatory Physiology 284, no. 6 (2003): H2269—H2276. http://dx.doi.org/10.1152/ajpheart.00774.2002.

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Oxytocin (OT) has been implicated in the cardiovascular responses to exercise, stress, and baroreflex adjustments. Studies were conducted to determine the effect of genetic manipulation of the OT gene on blood pressure (BP), heart rate (HR), and autonomic/baroreflex function. OT knockout (OTKO −/−) and control +/+ mice were prepared with chronic arterial catheters. OTKO −/− mice exhibited a mild hypotension (102 ± 3 vs. 110 ± 3 mmHg). Sympathetic and vagal tone were tested using β1-adrenergic and cholinergic blockade (atenolol and atropine). Magnitude of sympathetic and vagal tone to the heart and periphery was not significantly different between groups. However, there was an upward shift of sympathetic tone to higher HR values in OTKO −/− mice. This displacement combined with unchanged basal HR led to larger responses to cholinergic blockade (+77 ± 25 vs. +5 ± 15 beats/min, OTKO −/− vs. control +/+ group). There was also an increase in baroreflex gain (−13.1 ± 2.5 vs. −4.1 ± 1.2 beats · min−1 · mmHg−1, OTKO −/− vs. control +/+ group) over a smaller BP range. Results show that OTKO −/− mice are characterized by 1) hypotension, suggesting that OT is involved in tonic BP maintenance; 2) enhanced baroreflex gain over a small BP range, suggesting that OT extends the functional range of arterial baroreceptor reflex; and 3) shift in autonomic balance, indicating that OT reduces the sympathetic reserve.
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Larreta, Juantxo. "MEIN FREUND OTTO." mAGAzin Revista intercultural e interdisciplinar, no. 23 (2015): 52–53. http://dx.doi.org/10.12795/magazin.2015.i23.07.

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Bosniak, Stephen, and Marian Cantisano-Zilkha. "An introduction to the first issue of Volume 4." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 1. http://dx.doi.org/10.1076/otoo.4.1.1.8489.

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Lasudry, Jacques, Paul Jonckheere, Pierre-Yves Robert, and Jean-Paul Adenis. "Dermis-fat graft in orbital surgery." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 15–24. http://dx.doi.org/10.1076/otoo.4.1.15.8491.

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Adenis, J. P. "Introduction." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 2. http://dx.doi.org/10.1076/otoo.4.1.2.8498.

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Adenis, J. P., J. Y. Rulfi, and P. Y. Robert. "Surgical technical note: Evisceration using the Russian-doll technique and the parachute technique." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 25–29. http://dx.doi.org/10.1076/otoo.4.1.25.8496.

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Hintschich, Christoph, Frans Zonneveld, and Leo Koornneef. "Normal orbital volumes and its pathology in orbital socket surgery." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 3–14. http://dx.doi.org/10.1076/otoo.4.1.3.8497.

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Rulfi, J. Y., and J. P. Adenis. "Past and present trends in intraorbital biointegrated macroporous material implants." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 30–35. http://dx.doi.org/10.1076/otoo.4.1.30.8494.

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Mourgues, T., and J. P. Adenis. "Repair of hydroxyapatite orbital implant exposure with a conjunctival Muller muscle flap." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 36–38. http://dx.doi.org/10.1076/otoo.4.1.36.8493.

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Jordan, D. R. "Problems associated with porous orbital implants." Operative Techniques in Oculoplastic, Orbital and Reconstructive Surgery 4, no. 1 (2001): 39–47. http://dx.doi.org/10.1076/otoo.4.1.39.8492.

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Dissertations / Theses on the topic "OTKO"

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Peruzatto, Josi Maria Zimmermmann. "Comportamento sexual e expressão gênica de receptores em áreas encefálicas de fêmeas nocaute para o gene da ocitocina." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/122349.

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As relações sociais são construídas e mantidas a partir da interação entre os indivíduos. A ocitocina (OT), vasopressina (AVP), estrogênios (EST) e dopamina (DOPA), bem como seus respectivos receptores estão envolvidos na modulação do comportamento sexual de fêmeas. Estruturas do sistema nervoso central (SNC), tais como o bulbo olfatório (BO), o hipotálamo (HPT), o córtex pré-frontal (CPF) e o hipocampo (HPC) exercem importantes funções relacionadas à motivação sexual, reconhecimento de odores, memória e respostas emocionais. Em camundongos fêmeas, a OT é essencial para o comportamento de lordose e para estabelecer a preferência pelo parceiro. Este estudo teve como objetivo analisar o impacto do nocauteamento no gene da OT (OTKO) no comportamento sexual de camundongos fêmeas, na síntese hipotalâmica de AVP e na expressão gênica dos receptores de OT (OTR), AVP (AVPR1a), EST alfa (ERα), EST beta (ERβ) e DOPARD2 no BO, HPT, CPF e HPC. Foram utilizados 11 camundongos fêmeas (C57BL/6J) para o grupo controle (WT) e o mesmo número para o grupo OTKO. A detecção do transgene no genoma foi realizada pela técnica de reação em cadeia da polimerase (PCR) e os animais foram classificados como: WT (OT+/+), heterozigoto (OT+/-) e OTKO (OT-/-). O teste do comportamento sexual da fêmea foi realizado na noite do proestro e os parâmetros comportamentais avaliados foram: frequência, duração e latência de lordose, além da frequência de montas, bem como as posturas não receptivas e a locomoção. A coleta das estruturas encefálicas (BO, HPT, CPF e HPC) aconteceu na manhã seguinte do teste comportamental. Os cDNAs foram sintetizados por transcrição reversa seguida de reação em cadeia da polimerase (RT-PCR). A expressão gênica de cada receptor foi calculada a partir da fórmula 2-ΔΔCt. Os dados do registro comportamental e da expressão gênica foram expressos pela média, erro padrão da média (±EPM), analisados pelo teste de Mann-Whitney e o nível de significância aceito foi de p<0,05. Nossos resultados mostraram aumento significativo da latência e diminuição significativa da frequência e da duração do comportamento de lordose em fêmeas OTKO. Em relação às posturas não receptivas, fêmeas OTKO apresentaram diminuição significativa da latência e aumento significativo da frequência e da duração destas posturas. No que concerne à expressão gênica dos diferentes receptores, fêmeas OTKO apresentaram diminuição significativa da expressão gênica do OTR apenas no HPC em relação ao grupo WT. Verificamos que o grupo OTKO apresentou diminuição significativa da expressão gênica do AVPR1a apenas no HPT, mas aumento da expressão no HPC quando comparadas ao grupo WT. Também, fêmeas OTKO apresentaram diminuição significativa da expressão gênica do ERα e ERβ apenas no CPF quando comparadas ao grupo WT. Não foram encontradas diferenças significativas na expressão gênica do DOPARD2 em nenhuma das estruturas estudadas quando comparados os dois grupos estudados. No que diz respeito ao nocauteamento no gene da OT, nossos resultados mostraram que este não promove diferença significativa na síntese de RNAm de AVP no HPT do grupo OTKO quando ao grupo WT. Nossos principais achados nos permitem inferir que a ausência da OT dentro do SNC, bem como a importante alteração da expressão dos genes estudados (OTR, AVPR1a, ERα e ERβ) principalmente no CPF estão relacionados com a diminuição do comportamento sexual observada nas fêmeas OTKO.<br>Social relations are built and maintained from the interaction between individuals. Oxytocin (OT), vasopressin (AVP), estrogens (EST), dopamine (DOPA) and their receptors are involved in the modulation of sexual behavior in females. Structures of the central nervous system (CNS), such as the olfactory bulb (OB), hypothalamus (HPT), medial amygdale, prefrontal cortex (PFC) and hippocampus (HPC) have important functions related to sexual motivation, odor recognition, memory, and emotional responses. In mice, OT is essential for lordosis behavior and to establish the female preference for her partner. The experimental model using knockout animals for OT allows evaluating the physiological and behavioral changes generated from this genetic manipulation. This study aimed to analyze the impact of OT gene knockout (OTKO) in sexual behavior of female mice, in the synthesis hypothalamic of AVP and gene expression of OT receptors (OTR), AVP (AVPR1a), EST alpha (ERα), EST beta (ERβ) and DOPARD2 in OB, HPT, PFC and HPC. We used 11 female mice (C57BL/6J) for the control group (WT) and the same number for the OTKO group. Detection of the transgene in the genome was performed by polymerase chain reaction (PCR) and the animals were classified as: WT (OT+/+), heterozygous (+/-OT) and OTKO (OT-/-). The female sexual behavior test was performed on the evening of proestrus and these behavioral parameters were evaluated: frequency, duration and latency lordosis, frequency of mounts, as well as non-receptive positions and locomotion. The collection of brain structures (OB, HPT, PFC and HPC) happened the next morning the behavioral test. The CDNAs were synthesized by reverse transcription followed by polymerase chain reaction (RT-PCR). The gene expression of each receptor was calculated from the 2-ΔΔCt formula. Data from the behavioral record and gene expression were expressed as mean, standard error of the mean (±SEM) and analyzed by the Mann-Whitney test. In all cases, P<0.05 was considered statistically significant. Our results showed significant increase in latency and decrease in the frequency and duration of lordosis behavior in OTKO females. For non-receptive postures, OTKO females were significantly reduced latency and increased frequency and duration of these postures. Regarding the gene expression of different receptors, OTKO females showed significant decrease in OTR gene expression only in the HPC compared to WT group. We found that the OTKO group showed a significant decrease in gene expression of AVPR1a only in HPT, but increased expression in HPC as compared to WT group. Also, OTKO females showed significant decrease in gene expression of ERα and ERβ only the PFC when compared to the WT group. There were no significant differences in gene expression DOPARD2 in any of the studied structures when comparing the two groups. Regarding knockout in OT gene, our results showed that this does not promote significant difference in AVP mRNA synthesis in HPT of OTKO group when the WT group. Our main findings allow us to infer that the absence of OT within the CNS, as well as a significant changes in expression of the genes studied (OTR, AVPR1a, ERα and ERβ) mainly in the PFC are related to decreased sexual behavior observed in OTKO females.
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Müller-Kelwing, Karin. "Otto Fiebiger." Böhlau Verlag, 2020. https://slub.qucosa.de/id/qucosa%3A75044.

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Müller-Kelwing, Karin. "Otto Kleemann." Böhlau Verlag, 2020. https://slub.qucosa.de/id/qucosa%3A75103.

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Uhlig, Alexander. "Otto Kuhlmann (1873-1948) Architekt zwischen Tradition und Moderne /." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=970637233.

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Linnemannstöns, Karen [Verfasser], Andreas [Akademischer Betreuer] Wodarz, and Annette [Akademischer Betreuer] Borchers. "The transmembrane receptors Otk and Otk2 function redundantly in Drosophila Wnt signal transduction / Karen Linnemannstöns. Gutachter: Andreas Wodarz ; Annette Borchers. Betreuer: Andreas Wodarz." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044361360/34.

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Böhm, Hermann. "Die Tragödie des Austromarxismus am Beispiel von Otto Bauer : ein Beitrag zur Geschichte des österreichischen Sozialismus /." Frankfurt am Main [u.a.] : Lang, 2000. http://www.gbv.de/dms/sub-hamburg/314684638.pdf.

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Scholze, Bettina. "Otto Stobbe (1831 - 1887) : ein Leben für die Rechtsgermanistik /." Berlin : Duncker & Humblot, 2002. http://www.gbv.de/dms/sbb-berlin/343094614.pdf.

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Terhalle, Maximilian. "Deutschnational in Weimar : die politische Biographie des Reichstagsabgeordneten Otto Schmidt(-Hannover) 1888-1971 /." Köln : Böhlau Verlag, 2009. http://deposit.d-nb.de/cgi-bin/dokserv?id=3227718&prov=M&dok_var=1&dok_ext=htm.

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Sardón, José Luis. "Universidades: ¿hacia otro despojo?" Universidad Peruana de Ciencias Aplicadas (UPC), 2013. http://hdl.handle.net/10757/285450.

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Haack, Thomas. "Otto von Gierkes Kritik am ersten Entwurf des Bürgerlichen Gesetzbuches /." Frankfurt am Main ;Berlin [u.a.] : Lang, 1997. http://www.gbv.de/dms/spk/sbb/recht/toc/271840560.pdf.

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Books on the topic "OTKO"

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Castelnuovo, Juan R. Otro tiempo, otro héroe. s.n.], 2002.

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LeReau, Kara. Otto. Roaring Brook Press, 2011.

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Miklós, Hernádi. Otto. Magvető, 1990.

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Otto. Virago Press, 2005.

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Otoko. Media Fakutorī, 2000.

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Yū, Miri. Otoko. Shinchōsha, 2002.

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Dunn, Charlotte V. Lund. Otto. Charlotte's Precious Memories, 1998.

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1963-, Vukmir Janka, and Soros centar za suvremenu umjetnost--Zagreb., eds. Simpozij OTOK =: Symposium Otok Island. SCCA--Zagreb, 1997.

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Sáinz, Javier. Otro día: Memorias de otro preso. Manuscritos, 2010.

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Buckley, Leonard. Sir Ninian Comper, 1864-1960 and Howard Martin Otto (Otho) Travers, 1886-1948: A belated tribute. Ecclesiological Society, 1994.

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Book chapters on the topic "OTKO"

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Otto, Michael, and Johannes Merck. "Otto." In Deutsche Standards. Gabler Verlag, 2005. http://dx.doi.org/10.1007/978-3-322-82497-4_55.

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Christophersen, Paul. "Otto Jespersen." In Otto Jespersen. John Benjamins Publishing Company, 1989. http://dx.doi.org/10.1075/sihols.52.03chr.

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Villani, Cédric. "Otto calculus." In Grundlehren der mathematischen Wissenschaften. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-71050-9_15.

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Pahucki, John. "Rank, Otto." In Encyclopedia of Psychology and Religion. Springer US, 2014. http://dx.doi.org/10.1007/978-1-4614-6086-2_781.

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Korte, Hermann. "Flake, Otto." In Kindlers Literatur Lexikon (KLL). J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_6334-1.

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Weber, Wolfgang E. J. "Otto Brunner." In Kindler Kompakt Klassiker der Geschichtsschreibung. J.B. Metzler, 2016. http://dx.doi.org/10.1007/978-3-476-05530-9_49.

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Beighton, Peter, and Greta Beighton. "ULLRICH, Otto." In The Person Behind the Syndrome. Springer London, 1997. http://dx.doi.org/10.1007/978-1-4471-0925-9_84.

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Lorenz, Robert. "Otto Hahn." In Göttinger Köpfe. Vandenhoeck & Ruprecht, 2019. http://dx.doi.org/10.13109/9783666352140.89.

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Hargittai, István. "Otto Bastiansen." In Mosaic of a Scientific Life. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-34766-6_1.

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Halligan, Fredrica R., Nicholas Grant Boeving, John Pahucki, et al. "Rank, Otto." In Encyclopedia of Psychology and Religion. Springer US, 2010. http://dx.doi.org/10.1007/978-0-387-71802-6_781.

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Conference papers on the topic "OTKO"

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Salminen, Jukka, Seppo Eva, and Tom Ekegren. "Icebreaker OTSO Conversion." In Arctic Technology Conference. Offshore Technology Conference, 2016. http://dx.doi.org/10.4043/27459-ms.

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"OThO - PSK systems." In 2005 Optical Fiber Communications Conference Technical Digest. IEEE, 2005. http://dx.doi.org/10.1109/ofc.2005.192981.

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Kim, Tiffany Hyun-Jin, Payas Gupta, Jun Han, et al. "OTO." In the 2012 ACM conference. ACM Press, 2012. http://dx.doi.org/10.1145/2382196.2382239.

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Lastres, Luiz Fernando Martins, José Roberto De Souza Rocha, Marco Antonio Gonzalez De Almeida, and Leandro H. Benvenutti. "Sludge Formation in OTTO Cycle Engines." In 2005 SAE Brasil Fuels & Lubricants Meeting. SAE International, 2005. http://dx.doi.org/10.4271/2005-01-2173.

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Welty, Stephen. "Hybrid Stirling/Otto Cycle for CCHP." In ASME 2015 9th International Conference on Energy Sustainability collocated with the ASME 2015 Power Conference, the ASME 2015 13th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2015 Nuclear Forum. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/es2015-49048.

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The use of a novel thermodynamic cycle combined with a high efficiency expander and compressor provides a unique product opportunity for residential, commercial and industrial Combined Cooling, Heating and Power (CCHP) applications. The cycle can be described as a combination between a Stirling Cycle and an Otto Cycle with isothermal compression followed by constant volume heat addition then by isentropic expansion with the final process being heat addition or heat reject in either a constant volume or constant pressure process. The cycle can be run in an open cycle or a closed cycle with the closed cycle providing a more compact device for a given capacity while the open cycle provides an opportunity to get rid of one of the heat exchangers and cool or heat the air directly.
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Achleitner, E., H. Bäcker, and A. Funaioli. "Direct Injection Systems for Otto Engines." In SAE World Congress & Exhibition. SAE International, 2007. http://dx.doi.org/10.4271/2007-01-1416.

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Castro, Adriano C., Carlos H. Koster, and Erwin K. Franieck. "Flexible Ethanol Otto Engine Management System." In SAE Brasil '94. SAE International, 1994. http://dx.doi.org/10.4271/942400.

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Trevisan, Amarildo Luiz, Catia Piccolo Viero Devechi, and Gionara Tauchen. "A figura do otro na educação comparada." In Congreso Nacional de Educación Comparada. Universidad de La Laguna, 2018. http://dx.doi.org/10.25145/c.educomp.2018.16.100.

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Pérez Suárez, Ventura Alejandro. "El globo fraccionado." In III Congreso Internacional de Investigación en Artes Visuales :: ANIAV 2017 :: GLOCAL. Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/aniav.2017.4880.

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El presente documento trata de establecer una relación entre la globalidad y espacialidad, proponiendo un recorrido en las obras de Boullée, Buckminster Fuller, Frei Otto, Michael Webb y Prada Poole como puntos clave a la hora de entender el binomio goblal-local desde la creación del espacio y su dialéctica del límite (Sloterdijk, 2014).Por un lado, comprendemos globalidad bajo el prisma teórico de Peter Sloterdijk, en cuanto enuncia una teoría morfológica de la esfera. Esta última como aquella forma recurrente a lo largo de la historia de Occidente y su expansión. Por consiguiente, lo global será definido de su derivado y motivo "Globo" en paralelo a una la evolución arquitectónica o de Macroesferología(Vásquez, 2009).Por otro lado, lo local será encontrado en la misma teoría esferológica. Concretamente, desde la Microesferología como estudio de la unidad básica que son compuestas las sociedades: el individuo que coexiste. Ciencia proxémica, la Microesferología centrará su objeto de estudio en el espacio íntimo (Sloterdijk, 2004).Como conclusión, el baremo entre microesfera y macroesfera es posicionado según un cambio de escala y límite, ejemplificado en el recorrido de obra propuesta anteriormente. En paralelo, la consecuente transformación de lo global a lo local y viceversa se ve ayudada desde esta construcción del límite y escala.http://dx.doi.org/10.4995/ANIAV.2017.4880
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Garcia, Alvaro Cesar, and Cleber William Gomes. "Conceptual Analysis of Turbocompressor on Otto Cycle Engines." In 26th SAE BRASIL Inernational Congress and Display. SAE International, 2017. http://dx.doi.org/10.4271/2017-36-0167.

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Reports on the topic "OTKO"

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Posada, Carlos Esteban. Otro costo de una inflación perfectamente prevista. Banco de la República, 1997. http://dx.doi.org/10.32468/be.77.

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Trettin, H. P., and U. Mayr. Geology, Otto Fiord, District of Franklin, Northwest Territories. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1996. http://dx.doi.org/10.4095/208959.

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González-Gómez, Andrés, Luis Fernando Melo-Velandia, and Carlos Esteban Posada. Inflación y dinero en Colombia: otro modelo P-estrella. Banco de la República, 2006. http://dx.doi.org/10.32468/be.418.

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Giral, Francesc. Al otro lado del Aqueronte. Las monedas de las necrópolis altoimperiales de Empúries. Edicions de la Universitat de Lleida, 2017. http://dx.doi.org/10.21001/rap.2017.27.7.

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Arely Donis, C., and TG Martín Casado. Representación del Otro en publicidad social: Análisis publicidad gráfica en redes sociales de ONGD. Revista Latina de Comunicación Social, 2017. http://dx.doi.org/10.4185/rlcs-2017-1172.

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Mayr, U., J. C. Harrison, and B. Beauchamp. Geological map, parts of Cape Stallworthy and Otto Fiord map sheets (Hvitland Peninsula) Nunavut. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1999. http://dx.doi.org/10.4095/210942.

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Coutts, Lewis. Performance Oriented Packaging Testing of OTTO Fuel Drum for Packing Group II Liquid Hazardous Materials. Defense Technical Information Center, 1993. http://dx.doi.org/10.21236/ada265440.

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Suárez Bustamante, Gina Marcela, Dianys María Mercado Salgado, and Diana Ester Salgado Ruiz. “El Otro Soy Yo”: guía práctica para la atención integral a personas víctimas de violencia sociopolítica con énfasis solidario. Ediciones Universidad Cooperativa de Colombia, 2020. http://dx.doi.org/10.16925/gcgp.19.

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Suárez Bustamante, Gina Marcela, Dianys María Mercado Salgado, and Diana Ester Salgado Ruiz. “El Otro Soy Yo”: guía práctica para la atención integral a personas víctimas de violencia sociopolítica con énfasis solidario. Universidad Cooperativa de Colombia, 2020. http://dx.doi.org/10.16925/gcgp.20.

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Alvarado, Nathalie, and Viviana Vélez-Grajales. Dentro de las prisiones de América Latina y el Caribe: Una primera mirada al otro lado de las rejas. Inter-American Development Bank, 2019. http://dx.doi.org/10.18235/0001858.

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