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Journal articles on the topic 'Outer Root Sheath Melanocytes'

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1

Peters, Eva M. J., Desmond J. Tobin, Natasha Botchkareva, Marcus Maurer, and Ralf Paus. "Migration of Melanoblasts into the Developing Murine Hair Follicle Is Accompanied by Transient c-Kit Expression." Journal of Histochemistry & Cytochemistry 50, no. 6 (2002): 751–66. http://dx.doi.org/10.1177/002215540205000602.

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Disruption of the c-Kit/stem cell factor (SCF) signaling pathway interferes with the survival, migration, and differentiation of melanocytes during generation of the hair follicle pigmentary unit. We examined c-Kit, SCF, and S100 (a marker for precursor melanocytic cells) expression, as well as melanoblast/melanocyte ultrastructure, in perinatal C57BL/6 mouse skin. Before the onset of hair bulb melanogenesis (i.e., stages 0–4 of hair follicle morphogenesis), strong c-Kit immunoreactivity (IR) was seen in selected non-mela-nogenic cells in the developing hair placode and hair plug. Many of thes
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2

Li, Hanluo, Jule Kristin Michler, Alexander Bartella, et al. "Culturing of Melanocytes from the Equine Hair Follicle Outer Root Sheath." Processes 9, no. 1 (2021): 177. http://dx.doi.org/10.3390/pr9010177.

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Hair follicles harbor a heterogeneous regenerative cell pool and represent a putative low-to-non-invasively available source of stem cells. We previously reported a technology for culturing human melanocytes from the hair follicle outer root sheath (ORS) for autologous pigmentation of tissue engineered skin equivalents. This study translated the ORS technology to horses. We de-veloped a culture of equine melanocytes from the ORS (eMORS) from equine forelock hair follicles cultured by means of an analogue human hair follicle-based in vitro methodology. The procedure was adjusted to equine physi
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3

Na, G. Y., S. H. Paek, B. C. Park, et al. "Isolation and characterization of outer root sheath melanocytes of human hair follicles." British Journal of Dermatology 155, no. 5 (2006): 902–9. http://dx.doi.org/10.1111/j.1365-2133.2006.07502.x.

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4

Takada, Koji, Keikichi Sugiyama, Ikuo Yamamoto, Kenkichi Óba, and Takuji Takeuchi. "Presence of Amelanotic Melanocytes Within the Outer Root Sheath in Senile White Hair." Journal of Investigative Dermatology 99, no. 5 (1992): 629–33. http://dx.doi.org/10.1111/1523-1747.ep12668031.

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5

Vanscheidt, Wolfgang, and Thomas Hunziker. "Repigmentation by Outer-Root-Sheath-Derived Melanocytes: Proof of Concept in Vitiligo and Leucoderma." Dermatology 218, no. 4 (2009): 342–43. http://dx.doi.org/10.1159/000197467.

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6

Randall, Valerie A., Tracey J. Jenner, Nigel A. Hibberts, Isabel O. De Oliveira, and Tayyebeh Vafaee. "Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles." Journal of Endocrinology 197, no. 1 (2008): 11–23. http://dx.doi.org/10.1677/joe-07-0522.

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Androgens stimulate many hair follicles to alter hair colour and size via the hair growth cycle; in androgenetic alopecia tiny, pale hairs gradually replace large, pigmented ones. Since stem cell factor (SCF) is important in embryonic melanocyte migration and maintaining adult rodent pigmentation, we investigated SCF/c-Kit signalling in human hair follicles to determine whether this was altered in androgenetic alopecia. Quantitative immunohistochemistry detected three melanocyte-lineage markers and c-Kit in four focus areas: the epidermis, infundibulum, hair bulb (where pigment is formed) and
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7

Forrest, JW, MR Fleet, and GE Rogers. "Characterization of Melanocytes in Wool-bearing Skin of Merino Sheep." Australian Journal of Biological Sciences 38, no. 3 (1985): 245. http://dx.doi.org/10.1071/bi9850245.

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The distribution and character of melanocytes in the wool-bearing skin of Merino sheep of known genotypes were examined by light and electron microscopy. In black Merino sheep (ww, homozygous recessive), melanocytes were localized within three regions of the skin: epidermal-dermal border, outer root sheath and follicle bulb. Melanocytes within these regions were found to be actively producing melanin, had numerous dendritic extensions and were able to transfer melanin to adjacent keratinocytes. In a black Merino sheep whose fibres were white due to an experimentally induced copper deficiency t
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8

Limat, A., Denis Salomon, Pierre Carraux, Jean-Hilaire Saurat, and Thomas Hunziker. "Human melanocytes grown in epidermal equivalents transfer their melanin to follicular outer root sheath keratinocytes." Archives of Dermatological Research 291, no. 6 (1999): 325–32. http://dx.doi.org/10.1007/s004030050417.

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9

Horikawa, T., J. G. Morelli, D. A. Norris, and M. Ichihashi. "135 Inactive melanocytes in the outer root sheath of the hair follicle and the sebaceous gland." Journal of Dermatological Science 12, no. 2 (1996): 204. http://dx.doi.org/10.1016/0923-1811(96)89536-3.

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10

Forrest, JW, and MR Fleet. "Pigmented Spots in the WoolBearing Skin of White Merino Sheep Induced by Ultraviolet Light." Australian Journal of Biological Sciences 39, no. 2 (1986): 125. http://dx.doi.org/10.1071/bi9860125.

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Black-grey pigmented skin spots, some of which contained pigmented wool fibres, were observed in a flock of 8� 5-year-old white Merino ewes. The spots were concentrated along the backline and increased in number following shearing, suggesting exposure to sunlight to be of importance in the development of these non-congenital pigmented skin spots in genetically white Merino sheep. To test the effect of ultraviolet light, white Merino sheep, ranging in age from 3 to 8 years, had a closely clipped mid side area of wool-bearing skin irradiated on each of 28 consecutive days. Pigmented skin spots d
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11

Gad, HebaA, MarwaS El Hawary, HamdyH Swelim, YomnaI Mahmoud, and ShereenM Shawky. "Treatment of stable vitiligo using cultured and non-cultured autologous melanocytes from hair follicle outer root sheath cell suspension." Journal of the Egyptian Women's Dermatologic Society 17, no. 2 (2020): 104. http://dx.doi.org/10.4103/jewd.jewd_12_20.

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12

Cunliffe, William J., Susan P. Macdonald Hull, Michael Nutbrown, and Valerie A. Randall. "Abnormalities in the Ultrastructure of Melanocytes and the Outer Root Sheath of Clinically Normal Hair Follicles from Alopecia Areata Scalps." Journal of Investigative Dermatology 104, no. 5 (1995): 12–13. http://dx.doi.org/10.1038/jid.1995.34.

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13

Sülflow, Katharina, Marie Schneider, Tina Loth, et al. "Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel." Journal of Biomedical Materials Research Part A 104, no. 12 (2016): 3115–26. http://dx.doi.org/10.1002/jbm.a.35832.

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14

Savkovic, Vuk, Franziska Flämig, Marie Schneider, et al. "Polycaprolactone fiber meshes provide a 3D environment suitable for cultivation and differentiation of melanocytes from the outer root sheath of hair follicle." Journal of Biomedical Materials Research Part A 104, no. 1 (2015): 26–36. http://dx.doi.org/10.1002/jbm.a.35536.

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15

Commo, S., O. Gaillard, and B. A. Bernard. "Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath." British Journal of Dermatology 150, no. 3 (2004): 435–43. http://dx.doi.org/10.1046/j.1365-2133.2004.05787.x.

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16

Guo, Haiying, Yizhan Xing, Fang Deng, Ke Yang, and Yuhong Li. "Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles." PeerJ 6 (January 4, 2019): e6153. http://dx.doi.org/10.7717/peerj.6153.

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Secreted Frizzled-related Protein 4 (sFRP4) belongs to Wnt inhibitors. Previously, we reported that sFRP4 inhibited the differentiation of melanocyte. Here, by using of immunostaining, we showed that sFRP4 is expressed in both human and mouse hair follicles, especially in the outer root sheath and inner root sheath. To reveal the role of sFRP4 in hair follicle growth and hair cycle, we induced synchronized hair cycle in the dorsal skin of mice by depilation, and injected sFRP4 intradermally into the skin. By hematoxylin and eosin staining, we found that the regeneration of hair follicles was i
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17

Xiao, Lei, Xia Zhang, Zhiyi Chen, Yuting Li, Bing Li, and Lin Li. "ERK1/2 Pathway Is Involved in the Enhancement of Fatty Acids from Phaeodactylum tricornutum Extract (PTE) on Hair Follicle Cell Proliferation." BioMed Research International 2020 (October 30, 2020): 1–11. http://dx.doi.org/10.1155/2020/2916104.

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Extractions from Phaeodactylum tricornutum have been widely studied and evaluated to various biological effects. The aim of this study was to investigate the promotional effect of P. tricornutum extract (PTE) on the ERK1/2 signaling pathway involved in hair follicle cell proliferation. In order to illuminate the enhancement of PTE on hair growth by promoting proliferation of hair follicle cells, the activities of human hair follicle outer root sheath cell (HFORSC), human hair follicle germinal matrix cells (HFGMC), and hair epithelial melanocytes (HEM) were observed under PET treatment. Levels
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18

Horikawa, Tatsuya, David A. Norris, Thomas W. Johnson, et al. "DOPA-Negative Melanocytes in the Outer Root Sheath of Human Hair Follicles Express Premelanosomal Antigens But Not a Melanosomal Antigen or the Melanosome-Associated Glycoproteins Tyrosinase, TRP-1, and TRP-2." Journal of Investigative Dermatology 106, no. 1 (1996): 28–35. http://dx.doi.org/10.1111/1523-1747.ep12326989.

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19

Schneider, Marie, Andrea Lohrenz, Michael Cross, Michael C. Hacker, Jan C. Simon, and Vuk Savkovic. "A human serum-enriched medium formulation supports high viability and marker expression in primary melanocyte cultures from the outer root sheath and epidermis." Experimental Dermatology 27, no. 1 (2017): 87–90. http://dx.doi.org/10.1111/exd.13435.

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20

Reichel, Martin, and Edward R. Heilman. "Outer root sheath acanthoma." Journal of Cutaneous Pathology 26, no. 9 (1999): 441–43. http://dx.doi.org/10.1111/j.1600-0560.1999.tb01872.x.

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21

ITO, Masaaki. "Trichilemmoma.Cell biology of the normal human outer root sheath." Skin Cancer 10, no. 1 (1995): 33–39. http://dx.doi.org/10.5227/skincancer.10.33.

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22

Niderla-Bielinska, Justyna, Ewa Jankowska-Steifer, and Stanislaw Moskalewski. "Keratinization of outer root sheath cells is prevented by contact with inner root sheath of rat hair follicles." Archives of Dermatological Research 301, no. 5 (2008): 337–45. http://dx.doi.org/10.1007/s00403-008-0876-8.

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23

Satoh, T., Y. Mitoh, M. Katsumata, Y. Tokura, and M. Takigawa. "Follicular cyst derived from hair matrix and outer root sheath." Journal of Cutaneous Pathology 16, no. 2 (1989): 106–8. http://dx.doi.org/10.1111/j.1600-0560.1989.tb00019.x.

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24

ARASE, SEIJI, and NAOYUKI UCHIDA. "Culture of human outer root sheath cells from plucked hairs." Juntendo Medical Journal 37, no. 4 (1992): 542–49. http://dx.doi.org/10.14789/pjmj.37.542.

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25

Suhr, Ki Beom, and Jang Kyu Park. "Explant culture of outer root sheath cells from human hair." Journal of Dermatological Science 6, no. 1 (1993): 65. http://dx.doi.org/10.1016/0923-1811(93)91088-c.

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26

Tatsuta, Nazuko, and Tadashi Tezuka. "A novel monoclonal antibody to the outer root sheath cells." Journal of Dermatological Science 8, no. 2 (1994): 111–18. http://dx.doi.org/10.1016/0923-1811(94)90004-3.

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27

LIMAT, A., D. BREITKREUTZ, T. HUNZIKER, G. THIEKOETTER, and N. FUSENIG. "Environmental influences on outer root sheath cells from human hair follicle." Cell Biology International Reports 14 (September 1990): 54. http://dx.doi.org/10.1016/0309-1651(90)90323-q.

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28

Kurata, Sotaro, Satoshi Itami, Hiroto Terashi, and Susumu Takayasu. "Successful Transplantation of Cultured Human Outer Root Sheath Cells as Epithelium." Annals of Plastic Surgery 33, no. 3 (1994): 290–94. http://dx.doi.org/10.1097/00000637-199409000-00009.

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29

Pena, J. C. "Manipulation of outer root sheath cell survival perturbs the hair-growth cycle." EMBO Journal 18, no. 13 (1999): 3596–603. http://dx.doi.org/10.1093/emboj/18.13.3596.

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30

Kumaresan, M., R. Rai, and V. Sandhya. "Immunofluorescence of the outer root sheath: an aid to diagnosis in pemphigus." Clinical and Experimental Dermatology 36, no. 3 (2010): 298–301. http://dx.doi.org/10.1111/j.1365-2230.2010.03981.x.

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31

Mohanty, S., A. Kumar, J. Dhawan, V. Sreenivas, and S. Gupta. "Noncultured extracted hair follicle outer root sheath cell suspension for transplantation in vitiligo." British Journal of Dermatology 164, no. 6 (2011): 1241–46. http://dx.doi.org/10.1111/j.1365-2133.2011.10234.x.

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32

Sonoda, T., S. Itami, S. Kurata, and S. Takayasu. "Testosterone metabolism by cultured human epidermal keratinocytes and beard outer root sheath cells." Journal of Dermatological Science 4, no. 2 (1992): 137. http://dx.doi.org/10.1016/0923-1811(92)90236-5.

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33

Nessa, Mst Sayedatun, Nurul AKMN Kabir, Ashim Ranjan Barua, and Harasit Kumar Paul. "Role of direct immunofluorescence on outer root sheath of hair follicle in monitoring disease activity of pemphigus vulgaris." Journal of Pathology of Nepal 7, no. 2 (2017): 1162–67. http://dx.doi.org/10.3126/jpn.v7i2.17994.

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Background: Since the outer root sheath of hair follicle is structurally analogous to epidermal keratinocytes, direct immunofluorescence of hair may be an alternate method for monitoring disease activity of pemphigus vulgaris. Our objective was to find the effectiveness of direct immunofluorescence of outer root sheath as an alternate method in monitoring patients with pemphigus vulgaris. Materials and methods: Sixteen diagnosed cases of pemphigus vulgaris and in clinical remission for at least three months were enrolled. Skin biopsy sample and five plucked scalp hair samples of each patient w
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34

Braekevelt, Charlie R. "Fine structure of the pecten oculi of the mallard (Anas platyrhynchos)." Canadian Journal of Zoology 68, no. 3 (1990): 427–32. http://dx.doi.org/10.1139/z90-063.

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The pecten oculi of the mallard duck (Anas platyrhynchos) has been examined by light and electron microscopy. In this species, the pecten is of the pleated type and 12–14 accordion folds are joined apically by a heavily pigmented bridge of tissue which holds the pecten in a fanlike shape, widest at the base. It is situated over the optic nerve head and extends out into the vitreous. The entire pecten is enclosed by a fine basal lamina and hyalocytes are often present on its outer surface. Within each fold are numerous capillaries, larger blood vessels, and melanocytes. The capillaries are surr
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35

LIMAT, A., T. WYSS-CORAY, T. HUNZIKER, and L. R. BRAATHEN. "Comparative analysis of surface antigens in cultured human outer root sheath cells and epidermal keratinocytes: persistence of low expression of class I MHC antigens in outer root sheath cells in vitro." British Journal of Dermatology 131, no. 2 (2006): 184–90. http://dx.doi.org/10.1111/j.1365-2133.1994.tb08489.x.

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36

Kürşat Evrenos, Mustafa, Hakan Kerem, Peyker Temiz, Aylin Türel Ermertcan, and Levent Yoleri. "Malignant tumor of outer root sheath epithelium, trichilemmal carcinoma. Clinical presentations, treatments and outcomes." Saudi Medical Journal 39, no. 2 (2018): 213–16. http://dx.doi.org/10.15537/smj.2018.2.21085.

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37

Gupta, Somesh, Anil Kumar, Sujata Mohanty, Kanika Sahni, and Rajesh Kumar. "Extracted hair follicle outer root sheath cell suspension for pigment cell restoration in vitiligo." Journal of Cutaneous and Aesthetic Surgery 6, no. 2 (2013): 121. http://dx.doi.org/10.4103/0974-2077.112679.

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38

Miyauchi, Shunji, Ken Hashimoto, and Yoshiharu Miki. "The Innermost Cell Layer of the Outer Root Sheath Is Positive with Ki-67." Journal of Investigative Dermatology 95, no. 4 (1990): 393–96. http://dx.doi.org/10.1111/1523-1747.ep12555483.

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39

Jeschke, Marc G., Wolfgang Richter, and Stefan G. Ruf. "Cultured Autologous Outer Root Sheath Cells: A New Therapeutic Alternative for Chronic Decubitus Ulcers." Plastic and Reconstructive Surgery 107, no. 7 (2001): 1803–6. http://dx.doi.org/10.1097/00006534-200106000-00027.

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40

NAKAMURA, Fumio, Kunihiro KAJI, Shigeharu FUKUNAGA, Kaoru KOHNO, and Keiji KONDO. "The Structure Anchoring Underfur in Outer Root Sheath Cells of Telogen Mink Hair Follicles." Nihon Chikusan Gakkaiho 62, no. 8 (1991): 714–16. http://dx.doi.org/10.2508/chikusan.62.714.

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41

Zhang, Ying, Lulu Chen, Yu-Qing Jin, Fanfan Chen, and Wei Wu. "Enhanced Cultivation of Hair Follicle Outer Root Sheath Cells with K + M Culture Medium." Journal of Biomaterials and Tissue Engineering 9, no. 7 (2019): 890–97. http://dx.doi.org/10.1166/jbt.2019.2082.

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Hair follicle stem cells are vital seed cells for hair follicle and tissue engineering skin. However, there is no valid approach to obtain abundant cells within short times in vitro. The purpose of this study was to establish a new medium for culture and expansion of hair follicle outer root sheath (ORS) cells. ORS cells were harvested from human samples and cultured with a medium mixed with keratinocyte serum free medium and mouse embryonic fibroblasts suspension. The proliferation and vitality of ORS cells were evaluated. The cells exhibited typical cobblestone morphology with good adhesion
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42

CUI, Z. "Urokinase plasminogen activator (uPA) is a positive regulator of outer root sheath keratinocyte proliferation." Cell Biology International 28, no. 8-9 (2004): 571–75. http://dx.doi.org/10.1016/j.cellbi.2004.04.012.

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43

Cui, Zhifeng, Yanxia Hu, Hui Wang, et al. "Establishment and characterization of outer root sheath (ORS) cell line from Jining grey goat." Biotechnology Letters 34, no. 3 (2011): 433–40. http://dx.doi.org/10.1007/s10529-011-0799-x.

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44

Fujie, T., N. Uchida, T. Shikiji, Y. Urano, and S. Arase. "The interaction between human dermal papilla cells and outer root sheath cells in vitro." Journal of Dermatological Science 4, no. 2 (1992): 112. http://dx.doi.org/10.1016/0923-1811(92)90087-r.

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45

Savkovic, Vuk, Hanluo Li, Danilo Obradovic, et al. "The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath." Journal of Clinical Medicine 10, no. 5 (2021): 911. http://dx.doi.org/10.3390/jcm10050911.

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Neovascularization is regarded as a pre-requisite in successful tissue grafting of both hard and soft tissues alike. This study considers mesenchymal stem cells from hair follicle outer root sheath (MSCORS) as powerful tools with a neat angiogenic potential that could in the future have wide scopes of neo-angiogenesis and tissue engineering. Autologous MSCORS were obtained ex vivo by non-invasive plucking of hair and they were differentiated in vitro into both endothelial cells and vascular smooth muscle cells (SMCs), two crucial cellular components of vascular grafts. Assessment was carried o
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46

Hirai, Y., A. Nose, S. Kobayashi, and M. Takeichi. "Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesis." Development 105, no. 2 (1989): 271–77. http://dx.doi.org/10.1242/dev.105.2.271.

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Expression and the role of E- and P-cadherin in the histogenesis of the surface epidermis and hair follicles were examined using the upper lip skin of the mouse. P-cadherin is expressed exclusively in the proliferating region of these tissues, that is in the germinative layer of the surface epidermis, the outer root sheath and the hair matrix. E-cadherin is coexpressed in these layers but this molecule was also detected in non-proliferating regions such as the intermediate layer of the surface epidermis and the immature regions of the inner root sheath. Neither P- nor E-cadherin was detected i
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47

Nixon, A. J., L. Broad, D. P. Saywell, and A. J. Pearson. "Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets." Journal of Histochemistry & Cytochemistry 44, no. 4 (1996): 377–87. http://dx.doi.org/10.1177/44.4.8601697.

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Transforming growth factor-alpha (TGF-alpha) has been associated with cell proliferation of keratinocytes and implicated in hair growth. We therefore examined changes in the immunocytochemical localization of TGF-alpha and cell proliferation markers in the skin of two unrelated species in which hair cycles could be induced, to elucidate the role of this growth factor in the control of fiber growth. Skin was collected from melatonin-treated ferrets (Mustela putorius furo), untreated Romney sheep (Ovis aries), and New Zealand Wiltshire sheep in which interruption of wool growth had been photoper
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48

Onishi, Masazumi, Kazuhiro Takahashi, Fumihiko Maeda, and Toshihide Akasaka. "A Case of Basal Cell Carcinoma with Outer Hair Follicle Sheath Differentiation." Case Reports in Dermatology 7, no. 3 (2015): 352–57. http://dx.doi.org/10.1159/000442704.

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A 70-year-old Japanese man presented at our hospital with an asymptomatic, blackish, irregularly shaped plaque with a gray nodule in the periphery on his left lower leg. The lesion had been present for 10 years and had recently enlarged, associated with bleeding. Histopathologically, the tumor consisted of three distinct parts: The first part showed massive aggregation of basophilic basaloid cells with peripheral palisading and abundant melanin granules, and was diagnosed as solid-type basal cell carcinoma. The second part showed aggregation of clear cells with squamous eddies, and was diagnos
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49

Wu, Wei, Xiao-Li Wu, Yu-Qing Ji, and Zhen Gao. "Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro." Molecular Medicine Reports 16, no. 1 (2017): 95–100. http://dx.doi.org/10.3892/mmr.2017.6585.

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50

Fujie, Takeshi, Shoji Katoh, Hajimu Oura, Yoshio Urano, and Seiji Arase. "The chemotactic effect of a dermal papilla cell-derived factor on outer root sheath cells." Journal of Dermatological Science 25, no. 3 (2001): 206–12. http://dx.doi.org/10.1016/s0923-1811(00)00130-4.

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