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1

Hsueh, Aaron J. W., and David W. Schomberg, eds. Ovarian Cell Interactions. Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-8336-9.

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2

W, Hsueh Aaron J., Schomberg David W, and Ovarian Workshop on Ovarian Cell Interactions: Genes to Physiology (1992 : University of North Carolina-Chapel Hill), eds. Ovarian cell interactions: Genes to physiology. Springer-Verlag, 1993.

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3

Schatten, Heide, ed. Cell and Molecular Biology of Ovarian Cancer. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-58311-7.

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4

Weinstein, Ellen Michele. Inhibition of CA 125, a novel high molecular weight glycoprotein expressed by an ovarian carcinoma cell line: 0VCA 433, is related to glucocorticoid effects of altered cell growth, morphology, and growth pattern. s.n.], 1988.

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5

Linda, Giudice, Santa Eileen, Pool Robert, Institute of Medicine (U.S.). Board on Health Sciences Policy, and National Research Council (U.S.). Board on Life Sciences., eds. Assessing the medical risks of human oocyte donation for stem cell research: Workshop report. National Academies Press, 2007.

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6

Freedman, Jeri. Ovarian cancer: Current and emerging trends in detection and treatment. Rosen Pub. Group, 2009.

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7

Orr, Tamra. Ovarian tumors and cysts. Rosen Pub. Group, 2009.

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8

Nin, Gerardo Vázquez. Cell death in mammalian ovary. Springer, 2011.

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9

Byrne, Karen. Targeting of radiolabelled antibodies to ovarian carcinoma cells and spheroids. University of Manchester, 1994.

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10

Kubrakiewicz, Janusz. Struktura i funkcja zespołów komórek płciowych w politroficznych owariolach sieciarek (Insecta:Neuroptera). Wydawn. Uniwersytetu Wrocławskiego, 1998.

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11

universitet, Göteborgs, ed. Ovarian cells in superfusion: Temporal studies on cyclic AMP and steroid release in response to gonadotrophins. Department of Physiology, University of Göteborg, 1988.

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12

Jacobsen, G. Krag. Atlas of germ cells tumours. Munksgaard, 1989.

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13

Thalmann, Beat. Identification of novel modulators towards high cell density and high-producing Chinese hamster ovary suspension cell cultures as well as their application in biopharmaceutical protein production. Logos Verlag, 2015.

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14

K, Woodruff Teresa, and Snyder Karrie Ann, eds. Oncofertility: Fertility preservation for cancer survivors. Springer Verlag, 2007.

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15

1963-, Woodruff Teresa K., and Snyder Karrie Ann, eds. Oncofertility: Fertility preservation for cancer survivors. Springer, 2007.

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16

Stashwick, Caitlin, Brian J. Czerniecki, and Janos L. Tanyi. Dendritic Cell Vaccine Therapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0008.

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Dendritic cell vaccine therapy has emerged as an exciting new field in immunotherapy in ovarian cancer over the past two decades. This chapter reviews the biology of dendritic cells, including dendritic cell subsets, development, activation, and maturation as well as strategies for clinical use of dendritic cell vaccines. While there is encouraging data in preclinical work for dendritic cell vaccine, the outcomes of clinical trials have not shown robust responses. A summary of the clinical trials using dendritic cell vaccines in ovarian cancer is reviewed. Treatment-related toxicities and pote
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17

Hsueh, Aaron J. W., and David W. Schomberg. Ovarian Cell Interactions: Genes to Physiology. Springer, 2011.

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18

Hsueh, Aaron J. W., and David W. Schomberg. Ovarian Cell Interactions: Genes to Physiology. Springer, 2012.

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19

Ovarian Cell Interactions: Genes to Physiology. Springer, 2011.

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20

Farghaly, Samir A. Adoptive Cell Immunotherapy for Epithelial Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0005.

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The standard management for epithelial ovarian cancer (EOC) is a combination of aggressive debulking surgery with residual tumor of less than 1 cm and platinum-based chemotherapy. However, a high percentage of patients experience disease recurrence. Extensive efforts to find new therapeutic options have been made, albeit cancer cells develop drug resistance and malignant progression occurs. Novel therapeutic strategies are needed to enhance progression-free survival and overall survival of patients with advanced EOC. Several preclinical and clinical studies investigated feasibility and efficac
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21

Farghaly, Samir A., ed. Ovarian Cancer Immunotherapy. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.001.0001.

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Ovarian Cancer Immunotherapy provides a broad overview of several aspects of basic sciences and clinical and therapeutic aspects of immunotherapy for ovarian cancer, as well as state-of-the-art information on molecular genetics and biology. Chapters are written by a team of expert contributors from around the world and explore topics such as antibody therapeutics for ovarian carcinoma, emerging serum biomarkers, ovarian cancer immunity, adoptive cell immunotherapy, the biology of dendritic cells, the role of growth factors, and more. Readers will also gain a better understanding of the molecul
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22

Chapman, Hannah, and Christine Elwell. Ovarian and testicular cancer. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0328.

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Ovarian cancer is the fifth most common cancer in females in the UK. In contrast, testicular cancer is a rare disease: there were 2138 new cases of testicular cancer diagnosed in 2008 in the UK, and only 70 deaths. Ninety per cent of all ovarian cancers are of epithelial origin, although germ cell and sex cord–stromal cell tumours also occur. In contrast, 95% of testicular cancers are germ cell tumours, with stromal cell tumours and lymphomas making up the remaining 5%. This chapter discusses ovarian cancer and testicular cancer, including definitions of the diseases and their etiologies, typi
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23

Hsueh, Aaron J. W. Ovarian Cell Interactions: Genes to Physiology (Serono Symposia, USA). Springer, 1993.

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24

Monaco, Alexia. Living in Legacy: Ovarian Cancer from Cell to Soul. Lulu Press, Inc., 2024.

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25

Lavoué, Vincent, Patrick Legembre, Jean Levêque, Fabrice Foucher, Sébastien Henno, and Florian Cabillic. Ovarian Cancer Immunity. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0003.

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Epithelial ovarian cancer (EOC) is a significant cause of cancer-related mortality in women, and there has been no substantial decrease in the death rates due to EOC in the past three decades. Thus, basic knowledge regarding ovarian tumor cell biology is urgently needed to allow the development of innovative treatments for EOC. Traditionally, EOC has not been considered an immunogenic tumor, but there is evidence of an immune response to EOC in patients. Clinical data demonstrate that an anti-tumor immune response and immune evasion mechanisms are correlated with a better and lower survival, r
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26

Harnden, Patricia. Germ Cell Tumours V. Edited by Patricia Harnden. Springer-Verlag New York, Inc., 2002.

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27

Josephs, Debra H., Heather J. Bax, Giulia Pellizzari, James F. Spicer, Ana Montes, and Sophia N. Karagiannis. Antibody Therapeutics for Ovarian Carcinoma and Translation to the Clinic. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0001.

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Despite improvements over the past decade in the treatment of ovarian cancer, many patients are at risk of recurrent disease and emerging drug resistance. The increased selectivity and reduced toxicity of molecularly targeted anti-cancer agents renders them attractive for development in ovarian cancer, and monoclonal antibodies targeting ovarian cancer-specific tumor antigens represent the largest such group investigated in this clinical setting. This chapter describes examples of monoclonal antibodies clinically evaluated for efficacy in ovarian cancer. These agents recognize molecular target
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28

Alharbi, Yousef, Manish S. Patankar, and Rebecca J. Whelan. Antibody-Based Therapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0006.

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With their role in connecting disease-associated antigens to the cellular immune response, antibodies hold considerable promise as therapeutic agents. This chapter discusses three classes of therapeutic antibodies that have been developed for use in ovarian cancer therapy. The first includes antibodies selected against tumor-associated antigens such as MUC16/CA125, mesothelin, epithelial cell adhesion molecule, and folate receptor α‎. Antibodies in the second class target proteins such as CTLA-4 and PD1 that act as immune response checkpoint receptors. The third class of antibodies target secr
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29

Cell and Molecular Biology of Ovarian Cancer: Updates, Insights and New Frontiers. Springer International Publishing AG, 2024.

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30

Abe, Hiroyuki, Amane Sasada, Shigeki Tabata, and Minako Abe. Heat Shock Protein Vaccine Therapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0009.

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Despite advances in chemotherapeutic regimens, ovarian cancer has a poor prognosis. Therefore important effective treatments are urgently needed. Many studies have reported that the immune system plays a critical role in disease progression and overall survival. One known effective immunotherapy is the dendritic cell (DC)-based vaccine pulsed with tumor-associated antigens. This chapter reports on a method of production of a novel DC-based vaccine. The key technologies are (a) monocyte collection without leukapheresis, (b) monocyte expansion, (c) production of dendritic cells, (d) multiple ove
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31

Moerdler, Scott, and Xingxing Zang. PD-1/PDL-1 Inhibitors as Immunotherapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0010.

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Programmed death 1 (PD-1), a member of the B7-CD28 immunoglobulin superfamily, and its ligands PD-L1/PD-L2 inhibit T-cell activation. They also play a key role in the tumor microenvironment, allowing for cancer immune escape. PD-1 is induced on a variety of immune cells, including tumor-infiltrating lymphocytes (TILs), while PD-L1 is found on many types of solid tumors including ovarian cancer and some TILs. The use of immunocheckpoint inhibitors like anti-PD-1 and anti-PD-L1 therapies has been shown to reactivate the immune system to attack tumor cells. Ovarian cancers have been shown to be r
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32

Harnden, Patricia, William G. Jones, and Jonathan K. Joffe. Germ Cell Tumours V: The Proceedings of the Fifth Germ Cell Tumour Conference Devonshire Hall, University of Leeds, 13th-15th September 2001. Springer London, Limited, 2012.

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33

Harnden, Patricia, William G. Jones, and Jonathan K. Joffe. Germ Cell Tumours V: The Proceedings of the Fifth Germ Cell Tumour Conference Devonshire Hall, University of Leeds, 13th 15th September, 20. Springer London, Limited, 2013.

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34

Harnden, Patricia, William G. Jones, and Jonathan K. Joffe. Germ Cell Tumours V: The Proceedings of the Fifth Germ Cell Tumour Conference Devonshire Hall, University of Leeds, 13th-15th September, 2001. Springer, 2014.

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35

Jindal, Sangita Kathleen. Interaction and endocrine regulation of transforming growth factor-[alpha] and -[beta] systems in an ovarian cell model. 1995.

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36

Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Clinical management of cancer: flowcharts. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0021.

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Bladder cancer 670Breast cancer 671Cervical cancer 672Colon cancer 673Endometrial cancer 674Epithelial ovarian cancer 675Hepatocellular cancer 676Small-cell lung cancer 677Non-small cell lung cancer 678Oesophageal cancer 679Pancreatic cancer 680Prostate cancer 681Rectal cancer 682Stomach cancer ...
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37

Publications, ICON Health. The Official Patient's Sourcebook on Ovarian Germ Cell Tumors: A Revised and Updated Directory for the Internet Age. Icon Health Publications, 2002.

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38

Evangelou, Andreas Ioannou. Androgens reverse ovarian epithelial cell growth suppression by TGF-[beta]1 and regulate the expression of TGF-[beta] receptors and steroid receptor co-activators. 2003.

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39

Katabuchi, Hidetaka, Takashi Ohba, and Takeshi Motohara. Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects. Springer, 2018.

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40

Katabuchi, Hidetaka, Takashi Ohba, and Takeshi Motohara. Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects. Springer, 2018.

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41

Katabuchi, Hidetaka, Takashi Ohba, and Takeshi Motohara. Cell Biology of the Ovary: Stem Cells, Development, Cancer, and Clinical Aspects. Springer, 2018.

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42

Tworoger, Shelley S., Amy L. Shafrir, and Susan E. Hankinson. Ovarian Cancer. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0046.

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Worldwide, ovarian cancer is the seventh most commonly diagnosed cancer and the eighth most common cause of death from cancer. In 2012, 239,000 women were diagnosed with ovarian cancer and 152,000 women died of the disease worldwide. In the United States in 2015, an estimated 21,290 women were newly diagnosed with ovarian cancer and 14,180 died from the disease. Both incidence and mortality have decreased over time in the United States, with a 1.6% and 2.1% annual decrease, respectively, from 2003 to 2012. Ovarian cancers can arise from epithelial, germ, or stromal cells, although about 90% ar
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43

Reader, Jocelyn, Sarah Lynam, Amy Harper, Gautam Rao, Maya Matheny, and Dana M. Roque. Ovarian Tumor Microenvironment and Innate Immune Recognition. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0004.

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Ovarian adenocarcinoma is typified by detection at late stages with dissemination of cancer cells into the peritoneal cavity and frequent acquisition of chemoresistance. A number of studies show the importance of the tumor microenvironment and innate immune recognition in tumor progression. Ovarian cancer cells can regulate the composition of their stroma to promote the formation of ascitic fluid rich in cytokines and bioactive lipids such as PGE2, and to stimulate the differentiation of stromal cells into a pro-tumoral phenotype. In response, cancer-associated fibroblasts, cancer-associated m
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44

Footmarks of Innate Immunity in the Ovary and CytokeratinPositive Cells as Potential Dendritic Cells Advances in Anatomy Embyrology and Cell Biology Paperback. Springer, 2010.

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45

Brinton, Louise A., Mia M. Gaudet, and Gretchen L. Gierach. Breast Cancer. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0045.

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Breast cancer is the most frequently diagnosed cancer in women worldwide, with annual estimates of 1.7 million newly diagnosed cases and 522,000 deaths. Although more breast cancers are diagnosed in economically developed than in developing countries, the reverse is true for mortality, reflecting limited screening and less effective treatments in the latter. Breast cancer incidence has been on the rise in the United States for many years, but in recent years this is restricted to certain subgroups, while internationally there have been continued generalized increases, likely reflecting adoptio
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46

Vázquez-Nin, Gerardo H., María Luisa Escobar, M. De Felici, Olga Margarita Echeverría, and Francesca Gioia Klinger. Cell Death in Mammalian Ovary. Springer, 2014.

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47

Vázquez-Nin, Gerardo H., María Luisa Escobar, M. De Felici, Olga Margarita Echeverría, and Francesca Gioia Klinger. Cell Death in Mammalian Ovary. Springer London, Limited, 2011.

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48

Silverberg, Steven G., Junzo Kigawa, Tsunehisa Kaku, and Toru Sugiyama. Atlas of Clear Cell Carcinoma of the Ovary: A Pathological Guide. Springer, 2015.

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49

Silverberg, Steven G., Junzo Kigawa, Tsunehisa Kaku, and Toru Sugiyama. Atlas of Clear Cell Carcinoma of the Ovary: A Pathological Guide. Springer Japan, 2015.

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50

Silverberg, Steven G., Junzo Kigawa, Tsunehisa Kaku, and Toru Sugiyama. Atlas of Clear Cell Carcinoma of the Ovary: A Pathological Guide. Springer Japan, 2016.

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