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Daly, Caroline A. "Stable angina Europe - A survey of presentation to cardiologists, management, and clinical outcome over one year." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542943.
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Welburn, Kenneth. "Expectancies, perceptions and beliefs associated with the generalization of criticism skills over a one year interval." Thesis, University of Ottawa (Canada), 1989. http://hdl.handle.net/10393/5670.
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This study was designed to assess post-program cognitions and experiences which were hypothesized to play a role in the generalization of social skills over time. In particular, self-efficacy perceptions, outcome expectancies, outcome values, and anxiety were assessed through a Biographical Inventory before participation in a social skills program. The Inventory was then used to assess the subjects' experiences once a month for three months after the program, and one year following the program. Subjects who demonstrated generalization on in-vivo, role-play, or self-report measures of giving and receiving criticism over the one year were contrasted, on their responses to the Biographical Inventory, with those who showed little or no generalization. Results from the in-vivo and self-report measures indicated that the high generalization group differed from the low generalization group in their post-program experiences with giving and receiving criticism. Higher self-efficacy perceptions and the perception of positive consequences were evident for the high generalization group for experiences involving criticism. The results are discussed in relation to self-efficacy theory.
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Trohatos, Emily. "An evaluation of changes to the referral base of one orthodontic specialist over a 24-year period." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0005/MQ41641.pdf.
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Ragan, Gay A. "Teachers' perceptions and practices regarding the use of calculators in one district over a twenty-year period /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9998503.
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Paquette, Elizabeth. "Comparison of adaptation processes of parents with high-risk versus low-risk neonates over a one year interval." Thesis, University of Ottawa (Canada), 1988. http://hdl.handle.net/10393/5207.
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Gardner-Ray, Janet. "The impact of social groups and content on the maintenance of health behavior practices over a one-year period." Virtual Press, 1996. http://liblink.bsu.edu/uhtbin/catkey/1036819.
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During a period from May, 1993 to July of 1993, 309 employees of a large telecommunication's company selfselected to participate in an eight-week health promotion program designed to assist them in changing health behaviors. The program participants were then surveyed at the end of one-year to determine if they had maintained the health behavior changes practiced during the eight-week program and the impact of family, friends and coworkers on the level the participant was practicing the health behavior changes at the end of one-year.A growing body of evidence suggests ongoing research in the area of health behavior change because health related medical claims, absenteeism and decreased productivity continue to have serious financial consequences for American business. In Corporate America, health education programs have been organized to give employees the opportunity to change negative health habits and replace them with positive health habits. The assumption being, that healthier employees': (1) use less medical benefits (2) report fewer absent sick days and (3) are more productive employees.In addition, prior research indicates that being part of a social network or having access to social group support can help individuals decrease the level they practice negative health habits and increase the level they practice positive health habits. Thus, an understanding of social group support on the behavior change process is important to education professionals evaluating the effectiveness of health education programs within the corporate setting.This research study was designed to examine a health promotion program offered to employees of a large telecommunication company and the impact social groups andcontent had on the level participants changed their health related behaviors. The research assumed that examining encouragement and discouragement provided by: (1) family, (2) friends, and (3) coworkers would lead to a greater understanding of the impact social groups had on the level a participant practiced health behavior changes at the end of one year.This research indicated that social group participation played a significant role in the level a program participant was practicing health behavior changes at the end of one year. The analysis further indicated that support from family and friends were significant factors in the behavioral change process.In addition, organizational support prior to and during the "Health Habits Challenge" program had no significant impact on the level participants were practicing health behavior changes at the end of one year. However, participants receiving organizational support prior to and during the "Health Habits Challenge" program perceived their health as having improved during the one-year maintenance phase, while participants who did not receive organizational support reported their health status had declined.Relationships reported by this research study are sufficiently strong enough to warrant further research both qualitative and quantitative, to provide health educators with a better understanding of how social groups and organizational content influence health behavior changes. The factors are potentially important, not only for theoretical and research purposes but also for making practice and policy decisions appropriate to health promotion and health education.Department of Educational Leadership
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Cooper, Curtis. "Impact of highly active antiretroviral therapy on hepatitis C virus RNA levels over one year in HIV-HCV co-infected individuals." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6169.
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The effect of highly active antiretroviral therapy (HAART) on plasma HCV RNA level in HIV-HCV co-infected individuals is uncertain. This issue was investigated over 12 months in HIV-HCV co-infected subjects HAART-treated for at least six months and achieving HIV RNA suppression below 500 copies/mL. It was predicted that HCV RNA would initially increase from baseline, decline thereafter, and fall below baseline by 12 months. Frozen plasma specimens were used to measure quantitative HCV RNA levels in 50 HAART-treated co-infected subjects at baseline, 3, 6, and 12 months. A 0.5 logo increase in HCV RNA at 3 months was observed. This was followed by a decline below baseline. As low HCV RNA is a predictor of virologic response to HCV therapy, it may be advantageous to first achieve suppression of plasma HIV RNA level, gain immune reconstitution with HAART, and then initiate HCV antiviral treatment in HIV-HCV co-infected individuals.
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Archibald, Timothy, and Stacy Brown. "One year monitoring of potency change in commercial ibuprofen products stored in a household setting exposed to normal day-to-day temperature and humidity fluctuations." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/161.
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Introduction.Most over the counter (OTC) medications are labeled for storage in a room temperature environment (68 – 77oF) under dry conditions, i.e. kept away from moisture. Despite this, many households store medications in the bathroom, where both temperature and humidity extremes may be experienced during the course of the day. In this project, we sought to investigate the effect that long-term storage in a household bathroom had on potency of OTC ibuprofen (IBU) products. One degradation product, 4-isobutylacetophenone (4-IBP), has been shown to possess toxic properties. As such, the emergence of this breakdown product was also monitored.
Methods. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for the quantitative determination of IBU and 4-IBP in aqueous samples. The assay utilized a UCT C18 column (2.1 x 100 mm; 1.8 micron) with acetonitrile as the organic phase and water as the aqueous phase, run in isocratic mode (15% A: 85% B). Ibuprofen was ionized in negative electrospray mode (-ESI) using m/z 205.09 and 4-IBU in +ESI mode at m/z 177.15. Calibration curves were created in the ranges of 0.1 – 2 mg/mL (IBU) and 2 – 100 mg/mL. Three brands each of IBU tablets (200mg) and suspensions (100mg/5mL) were purchased and assayed for IBU concentration at the initiation of the study. The samples were stored in a household bathroom, while temperature and humidity were continuously recorded using Extech Instruments RHT10 data-logger. Three tablets were removed from each bottle, and three 5-mL aliquots were removed from each suspension, for analysis each month. The samples were digested in 0.1M HCl for 1hr using sonication, and diluted to assay concentration (2 mg/mL for tablets; 0.2 mg/mL for suspensions) using acetonitrile. Each sample was assayed in triplicate and percent recovery was calculated against freshly prepared standards of IBU.
Results. Acceptable potency range was defined as 90 – 110% of the labeled concentration. All tablets maintained acceptable average strength through three months, and a statistically significant change from initial concentration (as determined by a 2-way ANOVA, p = 0.05) was detected after 6 – 7 months. After ten months of storage, the average tablet strength was 74% of initial potency. All suspensions maintained acceptable average strength through five months, with statistically significant changes from initial concentration emerging after seven months storage. After 10 months of storage, the average suspension strength was 84% of initial potency. During the duration of the study, the average storage temperature was (20.9° C) and the average relative humidity was (65.7). The 4-IBU was not detected in any of the product samples during the duration of the study.
Conclusions.These data indicate that, while the toxic degradation product, 4-IBU, has not been detected following bathroom storage of commercial IBU products, significant changes in product potency can negatively affect product efficacy. The container-closure systems used in OTC ibuprofen products do not protect against the effects of ongoing fluctuations in environmental temperature and humidity. Data indicate that suspension products are more resistant to temperature and humidity fluctuations, at least to the degree that would be present in a household bathroom.
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Ballyram, T. "Prevalence and predictors of new episodes in patients with bipolar disorder at Dr George Mukhari hospital over a one year period (June 2007-June 2008)." Thesis, University of Limpopo (Medunsa), 2010. http://hdl.handle.net/10386/394.
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Thesis (MMed in Psychiatry) -- University of Limpopo, 2010Background: Bipolar disorder is a lifelong illness typically presenting with frequent relapses and/or recurrences. Bipolar disorder carries a high morbidity and mortality and can cause significant functional impairment. In understanding the relapsing course of the illness, chronicity may be reduced by preventing or delaying the occurrence of new episodes. Objectives: The objectives of this study were to establish the prevalence of new episodes in patients with bipolar I disorder and to determine predictors of new episodes. Methods: This was a retrospective, descriptive study based on the review of medical records of patients with bipolar I disorder seen at Dr. George Mukhari Hospital – psychiatry unit between the period of 1 June 2007 to 1 June 2008. Data concerning sociodemographic parameters of the patients and psychiatric information was collected using a data collection sheet. Results: Data was extracted and analysed from a total of 143 patient records. Ninety (63%) experienced new episodes and fifty-three patients (37%) did not have any new episodes. Seventy-nine patients (55%) had one or more manic episodes (mean=0.64) and nineteen (13.38 %) had one or more depressive episodes. (Mean=0.14). The maximum number of new episodes was 2 and the mean was 0.78. The most recent episode was manic in seventy-six patients (84%). The mean number of hospital admissions was 0.88. Of the patients that had new episodes, the age ranged from 18 to more than 55 years, the vast majority were black (94%) and of Christian faith (97%). More than half were female (58%) and single (49%), with 1-2 children (48%). The majority achieved high school education (60%), and were unemployed (70%). Only 47% were receiving a disability grant. New episodes were more prevalent in patients who experienced a younger age of onset of illness (41% in the 18-24 year age group) and who were ill for more than ten years (43%). Less than half had a positive family history of mental illness (43%), 39% had a history of substance use, the most common substance being alcohol (54%), and 39% suffered from one or more comorbid medical illnesses. 78% of the patients who had new episodes were on antipsychotics, 93% were on mood stabilisers, and 69% were on a xii combination of mood stabilisers and antipsychotics. The only factor that was significantly predictive of new episodes was poor compliance. Conclusion: There is a high prevalence of relapse in patients with bipolar I disorder, particularly to the manic pole. Compliance with medication remains a serious problem and is associated with the occurrence of new episodes. Improved treatments should include biopsychosocial strategies, identification of risk factors for relapse/recurrence and early and consistent intervention.
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Ballyram, Theona. "Prevalence and predictors of new episodes in patients with bipolar 1 disorder at Dr George Mukhari Hospital over a one year period (June 2007-June 2008)." Thesis, University of Limpopo (Medunsa Campus), 2010. http://hdl.handle.net/10386/454.
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Thesis (M Med (Psychiatry))University of Limpopo (Medunsa Campus), 2010.Background: Bipolar disorder is a lifelong illness typically presenting with frequent relapses and/or recurrences. Bipolar disorder carries a high morbidity and mortality and can cause significant functional impairment. In understanding the relapsing course of the illness, chronicity may be reduced by preventing or delaying the occurrence of new episodes. Objectives: The objectives of this study were to establish the prevalence of new episodes in patients with bipolar I disorder and to determine predictors of new episodes. Methods: This was a retrospective, descriptive study based on the review of medical records of patients with bipolar I disorder seen at Dr. George Mukhari Hospital – psychiatry unit between the period of 1 June 2007 to 1 June 2008. Data concerning sociodemographic parameters of the patients and psychiatric information was collected using a data collection sheet. Results: Data was extracted and analysed from a total of 143 patient records. Ninety (63%) experienced new episodes and fifty-three patients (37%) did not have any new episodes. Seventy-nine patients (55%) had one or more manic episodes (mean=0.64) and nineteen (13.38 %) had one or more depressive episodes. (Mean=0.14). The maximum number of new episodes was 2 and the mean was 0.78. The most recent episode was manic in seventy-six patients (84%). The mean number of hospital admissions was 0.88. Of the patients that had new episodes, the age ranged from 18 to more than 55 years, the vast majority were black (94%) and of Christian faith (97%). More than half were female (58%) and single (49%), with 1-2 children (48%). The majority achieved high school education (60%), and were unemployed (70%). Only 47% were receiving a disability grant. New episodes were more prevalent in patients who experienced a younger age of onset of illness (41% in the 18-24 year age group) and who were ill for more than ten years (43%). Less than half had a positive family history of mental illness (43%), 39% had a history of substance use, the most common substance being alcohol (54%), and 39% suffered from one or more comorbid medical illnesses. 78% of the patients who had new episodes were on antipsychotics, 93% were on mood stabilisers, and 69% were on a xii combination of mood stabilisers and antipsychotics. The only factor that was significantly predictive of new episodes was poor compliance. Conclusion: There is a high prevalence of relapse in patients with bipolar I disorder, particularly to the manic pole. Compliance with medication remains a serious problem and is associated with the occurrence of new episodes. Improved treatments should include biopsychosocial strategies, identification of risk factors for relapse/recurrence and early and consistent intervention.
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Machingaidze, Pamela Rudo. "The clinical use and indications for head computed tomography scans in paediatric ambulatory care (short stay ward and medical emergencies) at a children’s hospital over a one-year period, 1st January-31st December 2013." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29345.
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Background: Computed tomography (CT) imaging is an indispensable tool in the management of acute paediatric illness. It offers quick answers, allowing timely lifesaving decision-making. Clinical evidence is required to maximise its benefits against radiation-exposure risks to patients and cost to the healthcare system.
Aims: The study aimed to retrospectively investigate clinical presentation and indications of head CT at a tertiary paediatric hospital.
Methods: Records of children presenting with acute illness to the medical emergency unit, excluding trauma, of Red Cross War Memorial Children’s Hospital, Cape Town, over one year (2013) were retrospectively reviewed. Participants were included if they underwent head CT scan within 24 hours of presentation. Clinical data were extracted from records and CT findings reported by a paediatric radiologist.
Results: Inclusion criteria were met by 311 patients; 188 (60.5%) were boys. The median age was 39.2 (IQR 12.6-84.0) months. Commonest indications were seizures (n=169;54.3%), reduced level of consciousness (n=140;45.0%), headache (n=74;23.8%) and suspected ventriculoperitoneal shunt (VPS) malfunction (n=61;19.7%). In 217 (69.8%) patients CT showed no adverse findings. In the 94 (30.2%) patients in whom CT abnormalities were detected, the predominant findings were hydrocephalus (n=54;57.4%) and cerebral oedema (n=29;30.9%). Abnormal CT findings were commoner in patients with nausea or vomiting (n=21;9.3%, p=0.05) papilloedema (n=3;1.3%, p=0.015) and long tract signs (n=23;10.2%, p=0.02). Forty-seven patients (15.1%) required surgical intervention after CT of which 40 (85.1%) needed a ventricular drainage procedure. A larger proportion of patients with VPS (25/62;40.3%) required surgical intervention compared to patients without VPS (22/249;8.8%, p <0.001)
Conclusion: Most children presenting with acute illness (excluding trauma) and undergoing emergency head CT have normal findings. Patients with ventriculoperitoneal shunts constituted a large proportion of patients requiring intervention after CT. Considerations should be made to use clinical presentation to select patients most likely to benefit from CT.
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Ejaz, Bushra. "Tick-Borne Encephalitis In Sweden : What Is Happening In My County Over The Past 35 Years?" Thesis, Linnéuniversitetet, Institutionen för hälso- och vårdvetenskap (HV), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-104632.
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Tick-borne encephalitis is a vector-borne zoonotic disease with more than 12,000 annual clinical reported cases globally (WHO, 2021). Tick-borne encephalitis is caused by the flavivirus and transferred by Ixodes ricinus from roe deer to human and affects the central Nervous system. Climate change also increases tick-borne encephalitis incidences in Sweden and fluctuated considerably from year to year. A quantitative study design with secondary data was conducted to analyze the spatial and temporal pattern of Tick-borne encephalitis in Sweden from 1986-2020. The distribution of Tick-borne encephalitis within age and sex, along with other factors were also analyzed. The results showed that Tick-borne encephalitis with passing each year spread across the country. Male and age group, 50-59, have more incidence of Tick-borne encephalitis. Incidents were associated with climate conditions such as temperature and precipitation, which provided a favorable environment for Ixodes ricinus for its lifecycle activities, host searching, and disease transmission. Roe deer population, other vertebrates abundance, vaccination, population interest, economy, and land change are the critical factors that facilitate the disease incidence or control. People who visit forests for hunting, trekking, leisure, and professional activities without proper immunity and preventive measures are at risk to infect with Tick-borne encephalitis. The theory One health approach showed suitable performance for the control of this vulnerable climate zoonotic disease.
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Vincze, Szilvia [Verfasser]. "Microevolution of S. pseudintermedius isolated from one canine patient over a time span of seven years / Szilvia Vincze." Berlin : Freie Universität Berlin, 2017. http://d-nb.info/114004348X/34.
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Wasilewski, Benjamin. "Geochronology, Petrogenesis and Crustal Evolution of the Saglek-Hebron Complex (Northern Labrador): Over One Billion Years of Archean Geological History." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39617.
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The Saglek-Hebron Complex (SHC) in Northern Labrador represents one of the oldest terrains on Earth and it is closely related to the Archean Itsaq Gneiss Complex (IGC) in Greenland. The SHC is a typical granite-greenstone terrain that recorded over one billion years of magmatic history between ~3900 Ma and ~2700 Ma. Our geochronological and geochemical study shows that the SHC includes five generations of trondhjemite-tonalite-granodiorite suites (TTG): the ~3870 Ma Iqaluk gneiss, the ~3750 Ma Uivak I gneiss, the ~3600 Ma Uivak II gneiss, the newly described ~3300 Ma Iluilik gneiss, and the ~3220 Ma Lister gneiss. These granitoid units are mostly consist of trondhjemite and tonalite with only rare granodiorites that appear to define a distinct unit formed at ~3330 Ma and newly defined as the Iluilik gneiss. The Iluilik granodiorite appears to be derived from a Hadean mafic crust as supported by its combined whole-rock geochemical composition, its positive µ142Nd value of +6, and its low εHf= -6 and εNd= -3, at 3300 Ma. SHC granites were emplaced throughout the Archean, from 3800 to 2700 Ma, but are predominant in the Neoarchean. They appear to have been mainly formed from the reworking of the SHC TTG, as supported by their low εHf and εNd initial values of respectively -16 and -11 at 2700 Ma. The granitoids include numerous enclaves of supracrustal rocks from various size, up to a few kilometers in scale, consisting of metavolcanic metasedimentary rocks. Previous work has suggested that they were formed at two different ages, with the younger Upernavik supracrustal unit deposited around 3400 Ma and the older Nulliak supracrustal assemblage deposited at around 3750 Ma. We show that both units are comparatively geochemically homogeneous with no distinction between the mafic and ultramafic rocks from both supracrustal assemblages. They mainly consist of mafic metavolcanic amphibolites with tholeiitic affinities, consistent with more depleted mafic and more enriched compositions produced by magmatic differentiation. Their complementary Eu anomaly and whole-rock geochemistry suggest that they formed from fractional crystallization of gabbroic assemblage that derived from similar if not the same parental magma. The mafic metavolcanic rocks are also often associated with ultramafic rocks that we divided into two distinct units, respectively referred as the high-Fe and the low-Fe ultramafic rocks, characterized by different FeO contents and Al/Ti ratio. They both represent olivine-rich cumulative rocks derived from distinct parental komatiitic basalt magmas. Our interpretation contrasts with previous work suggesting that the SHC ultramafic rocks were komatiites and slivers of residual lithospheric mantle. Most SHC TTG exhibit a positive 142Nd anomaly, as high as µ142Nd = +15, suggesting a source formed by differentiation in the Hadean. This 142Nd isotopic composition is similar to the Nulliak supracrustal rocks that exhibit on average a µ142Nd of +10. TTG is generally considered to derive from a mafic precursor. This study therefore shows that mafic crustal source of the SHC Eoarchean TTG, potentially the Nulliak metabasalts, derives from an ancient highly depleted mantle, described as the Saglek mantle, sharing a similar early history as the mantle reservoir involved in the formation of the ancient Itsaq terrane of southwest Greenland. The Saglek depleted mantle is interpreted to have formed at ~4400 Ma, exhibit highly depleted signature with a 147Sm/144Nd ratio of 0.221-0.240.
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Ayoola, Omolola. "The effect of maternal malaria during pregnancy on birth size, early childhood growth and blood pressure in Nigerian children." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/the-effect-of-maternal-malaria-during-pregnancy-on-birth-size-early-childhood-growth-and-blood-pressure-in-nigerian-children(04d1c812-8fff-41b7-9db6-8f9243882de1).html.
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Background: In Nigeria, there is an escalating incidence of hypertension, its complications and other cardiovascular risks, likely to have their origins in early life. Malaria is still hyperendemic, with pregnant women at increased risk, with associated consequences of maternal anemia and high rates of delivering low birth-weight babies. Aims and Hypothesis: In this study, we have tested the hypothesis that malaria in pregnancy will not only enhance the risk of small birth size and poor infant growth, but will also generate higher blood pressures in infancy and beyond. We also tested the hypothesis that metabolic markers in pregnant mothers affected by malaria would relate to infant birth size. Thus the aims of this project were: 1) to define relationships between the type of malaria exposure and birth size, 2) to characterize the association between maternal and cord metabolic biomarkers and birth size on the background of prenatal malaria exposure and 3) to examine the effect prenatal malaria exposure on first year growth and whether higher blood pressure (BP) is generated. Methods: Healthy pregnant women were recruited and followed at Adeoyo Maternity Hospital, Ibadan. Anthropometric, BP, and biomarkers (lipids, glucose, insulin and TNFα) measurements were obtained in the mothers at booking. Birth size and growth at 3 and 12 months along with biomarkers (as above) and IGF-I measures in cord blood were assessed in the infants. Blood films for malaria parasites were taken throughout pregnancy including delivery and in all babies. Women were grouped to distinguish between the timing of malaria parasitaemia (either during pregnancy only or during pregnancy and at delivery) and the severity of malaria infection (low vs high parasite load). At birth, 436 mother-baby pairs were measured. 467 maternal samples were obtained for metabolic profile and 187 cord blood samples. 318 babies were all followed from birth to 3 and 12 months. Results: Malaria parasitaemia was found in 48% of the women, associated with younger maternal age, being primigravid and a lower haematocrit. Babies of mothers with high parasitaemia through pregnancy had the smallest birth growth parameters compared with those without malaria (weight, length, and head circumference were smaller by 300g, 1.1cm and 0.7cm respectively, all p≤0.005) but their systolic BP (SBP) and diastolic BP (DBP) adjusted for weight were higher than those with low parasitaemia by 1.7 and 1.4 mmHg/kg respectively. SBPs were lowest in babies of mothers with malaria at delivery implying an acute effect on the babies’ circulation. Mothers with malaria had significantly lower lipids (except triglycerides) but higher TNFa, effect not seen in cord blood. Cord IGF-I was significantly lower in babies whose mothers had malaria. Significant determinants of birth size were maternal total cholesterol, LDL- cholesterol, insulin, malarial status and cord insulin and IGF-I. Babies exposed to maternal malaria remained smaller at 1 year, most marked in boys, whose SBP adjusted for weight at 3 and 12 months was higher than those not exposed. Change in SBP over the first year was greater in boys than girls while the change in girls was greater in those exposed to maternal malaria than those not exposed (18.7 vs 12.7 mmHg, 95% CI 1-11, p=0.02). 11% of boys ( > twice expected) had BP >95th percentile (hypertensive, US criteria) of whom 68% had maternal malaria exposure. Gender, maternal malaria exposure and weight change were all independently associated with increased change in BP to 1 year. Conclusion: Intrauterine exposure to malaria appears not only to have an important impact on birth size but also gender-dependent effects on growth and changes in infant BP. These findings have potential implications for cardiovascular health in sub-Saharan Africa and may contribute to the global burden of hypertension.
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Barclay-Goddard, Ruth. "Health related quality of life over one year post stroke: identifying response shift susceptible constructs." 2008. http://hdl.handle.net/1993/3072.
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Problem: Many individuals with chronic illnesses such as stroke and ongoing activity limitations report self-perceived health related quality of life (HRQL) that is similar to that of healthy individuals. This phenomenon is termed response shift (RS). RS describes how people change: internal standards in assessing HRQL (recalibration), values (reprioritization), or how they define HRQL (reconceptualization), after an event such as stroke. Changes in HRQL post stroke may be inaccurate if RS is not taken into account. Increased knowledge of RS may affect the way in which HRQL measures are used, both clinically and in research. The overall objective was to assess RS in construct specific HRQL models post stroke: physical function, mental health, and participation.
Methods: Data were analysed from the longitudinal study “Understanding Quality of Life Post-Stroke: A Study of Individuals and their Caregivers”. Six-hundred and seventy- eight persons with stroke at 1, 3, 6, and 12 months post stroke participated. Generic and stroke specific HRQL measures were collected. Descriptive analysis was completed with SAS, and identification of RS utilized structural equation modeling with LISREL.
Results: Mean age of participants was 67 years (SD 14.8), and 45% were female. RS was identified in mental health using a framework which was developed for identifying RS statistically with multiple time points. RS was also identified in physical function where it had not been expected, possibly due to the self perceived nature of the response options. The effect size of change in physical function was affected by the presence of RS. The timing of RS in mental health and physical function was primarily around the 12 month time period, and predominantly recalibration RS. RS was also identified in participation.
Conclusions: The framework that was developed was useful in identifying RS and incorporated important issues such as multiple testing and validation of the model. The presence of RS affects measurement of HRQL constructs post stroke; recalibration RS can be measured clinically with specific methods to account for RS. RS should also be measured in research studies to ensure accurate measurement of change. Future research should evaluate additional models in stroke and other populations.October 2008
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Segerhammar, Ivan. "Anaplastic carcinoma of the thyroid: treatment and outcome over a 13 year-period at one institution." Thesis, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-215627.
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Gentry, Jennifer B. "Quantification and distribution of human noroviruses from oyster, water, and plankton samples over a one-year period from two Georgia estuaries." 2008. http://purl.galileo.usg.edu/uga%5Fetd/gentry%5Fjennifer%5Fb%5F200805%5Fms.
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Chao, Yu-Hsien, and 趙玉嫻. "Tempo-spatial change of Pushihge - The migration of ethnic groups and its land reclamation around the middle section of the East Rift Valley over the past one hundred year." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/uxnrt3.
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碩士國立東華大學
臺灣文化學系
100
Studies of eastern Taiwan related to its regional characteristics, population and industrial development often took the concept that it is extremely different from the western by its natural environment, the population composed of a high rate of Aboriginal people, the land development was dominant by the national power, but the lack of management made it became a wretched border area. However, the area of Yuli located in the middle of East rift valley had an extremely development experience from above-mentioned characteristics, but few researchers discuss the reasons. The study chose the area of the middle section of the East Rift Valley (Yuli sub-prefecture, an administrative boundary during the Japanese colonial period, roughly today’s Yuli, Fuli and Jhuosi Township) to examine the tempo-spatial change over the past one hundred year. This study use the relevant historical documents, statistics, previous studies to show the historical context of ethnic migration in the region and local population structure change; on the other hand, with the help of digitized historical maps provided by the National Digital Archives Program, the study will compare the land use change using Geographic Information System(GIS) to present the spatial heterogeneity in the area. The result shows that the study area not only dominated by the national power, but also strongly driven by the local ethic groups presented in its dynamic relationships between the people and the land. During the Ching dynasty, they faced the threaten of Bunun that resulted the development of settlement and land use concentrated in the eastern side of river; after the occupation of Japan colonial government, with the affect of group relocation, the land reclamation show the pattern of expansion-convergence-expansion. After the WW2, the development followed the traffic line and obtained from the mountain and river. The above-mentioned background caused the uneven sex ratio and population structure in present Yuli county, and continued the spatial heterogeneity.
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Sjögren, Tuulikki. "Effect of a workplace physical exercise intervention on the functioning, work ability, and subjective well-being of office workers a cluster randomized controlled cross-over trial with a one-year follow-up in the workplace /." 2006. http://www.oregonpdf.org.
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Thesis ([Ph. D.])--University of Jyväskylä, 2006.Originally issued in series: Studies in sport, physical education and health ; 118 Includes bibliographical references (leaves 81-91). Also available online (PDF file) by a subscription to the set or by purchasing the individual file.