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Journal articles on the topic 'Overdrive mechanism'

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Published: 3 June 2025
Last updated: 31 July 2025

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1

Chechekhin, Vadim, Anastasia Ivanova, Konstantin Kulebyakin, et al. "Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension." Cells 12, no. 4 (2023): 585. http://dx.doi.org/10.3390/cells12040585.

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Hypertension is a major risk factor for cardiovascular diseases, such as strokes and myocardial infarctions. Nearly 70% of hypertension onsets in adults can be attributed to obesity, primarily due to sympathetic overdrive and the dysregulated renin-angiotensin system. Sympathetic overdrive increases vasoconstriction via α1-adrenoceptor activation on vascular cells. Despite the fact that a sympathetic outflow increases in individuals with obesity, as a rule, there is a cohort of patients with obesity who do not develop hypertension. In this study, we investigated how adrenoceptors’ expression a
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Kunysz, A. M., A. Shrier, and L. Glass. "Bursting behavior during fixed-delay stimulation of spontaneously beating chick heart cell aggregates." American Journal of Physiology-Cell Physiology 273, no. 1 (1997): C331—C346. http://dx.doi.org/10.1152/ajpcell.1997.273.1.c331.

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Spontaneously beating embryonic chick atrial heart cell aggregates were stimulated with depolarizing current pulses delivered at a fixed delay after each action potential. This preparation is an experimental model of a reentrant tachycardia. During fixed-delay stimulation, bursting behavior was typically observed for a wide range of delays. Episodes of bursting at a rate faster (slower) than control were followed by overdrive suppression (underdrive acceleration). We use a simple nonlinear model, based on the interaction between excitability and overdrive suppression, to describe these dynamic
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Arnar, David O., Dezhi Xing, and James B. Martins. "Overdrive pacing of early ischemic ventricular tachycardia: evidence for both reentry and triggered activity." American Journal of Physiology-Heart and Circulatory Physiology 288, no. 3 (2005): H1124—H1130. http://dx.doi.org/10.1152/ajpheart.01162.2003.

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Entrainment can be a useful method to identify reentry as a mechanism of ventricular tachycardia (VT). In this study, we evaluated the effect of gradually decreasing cycle lengths of overdrive pacing for stable VT induced in a canine model 1–3 h after coronary occlusion. Intact dogs underwent anterior descending coronary artery occlusion after instrumentation of the risk zone with 21 multipolar plunge needles, each recording 6 bipolar electrograms. Overdrive pacing was attempted if the animals had sustained hemodynamically stable VT, looking for evidence of entrainment. Subsequent three-dimens
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4

Kedar, Pimparkar. "AUTOMATIC KINEMATIC LINKAGE TRANSMISSION USING OVERDRIVE." International Journal of Advances In Scientific Research and Engineering (IJASRE) 3, no. 4 (2017): 145–49. https://doi.org/10.5281/zenodo.583839.

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<em>In this paper we have tried to explain combined use of lesteran’s concept of automatic transmission and overdrive mechanism. In lesteran’s concept he replaced gearbox with automatic mechanical torque convertor assembly. While overdrive consists of an electrically or hydraulically operated </em><em>epicycle gear</em><em> train bolted behind the </em><em>transmission</em><em> unit which allows the engine to operate at a lower RPM for a given road speed. This allows the vehicle to achieve better fuel efficiency, and often quieter operation on the highway</em>
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Mohanan Nair, Krishna Kumar, Narayanan Namboodiri, Hiren Kevadiya, and Ajitkumar Valaparambil. "Atrial overdrive pacing during LBBB tachycardia: What is the mechanism?" Pacing and Clinical Electrophysiology 41, no. 4 (2018): 411–13. http://dx.doi.org/10.1111/pace.13302.

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6

Gorev, M. V., Sh G. Nardaia та F. G. Rzaev. "Pacing maneuvers for supraventricular tachycardia differential diagnosis: ventricular overdrive pacing". Journal of Arrhythmology 29, № 3 (2022): 54–70. http://dx.doi.org/10.35336/va-2022-3-08.

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The accurate tachycardia mechanism verification is the most important condition for high effectiveness and safety of the supraventricular tachycardia ablation. Ventricular overdrive pacing - is a simple and useful diagnostic maneuver, frequently used in the supraventricular tachycardia diagnosis. The conditions for its performance and interpretation in the standard and rare situations are described in this review.
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7

Ye, Hui, Zhi Fang, Prabhakar Tamirisa, Gaurav Jain, and Erik Scott. "(Digital Presentation) Thermal Acceleration Model for the Capacity Fade of a Rechargeable Li Ion Battery and Its Validation with 10+ Years of Testing Data." ECS Meeting Abstracts MA2022-01, no. 2 (2022): 388. http://dx.doi.org/10.1149/ma2022-012388mtgabs.

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Rechargeable Li ion batteries have become not only a major power source for consumer electronics, but also a critical power source for high demanding applications like electrical vehicles, portable military devices and medical devices. Medtronic, one of the leading medical device companies has developed a breakthrough rechargeable Li ion battery technology-OverdriveTM to power implantable neurostimulators such as Intellis and Interstim Micro. OverdriveTM batteries have exceptional stable performance and fast charging capability. Figure 1 shows design verification test of capacity stability und
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8

Greenberg, Yisachar J., and Mario Vassalle. "On the mechanism of overdrive suppression in the guinea pig sinoatrial node." Journal of Electrocardiology 23, no. 1 (1990): 53–67. http://dx.doi.org/10.1016/0022-0736(90)90151-q.

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9

Grace, Anthony A., and Daniela L. Uliana. "Insights into the Mechanism of Action of Antipsychotic Drugs Derived from Animal Models: Standard of Care versus Novel Targets." International Journal of Molecular Sciences 24, no. 15 (2023): 12374. http://dx.doi.org/10.3390/ijms241512374.

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Therapeutic intervention for schizophrenia relies on blockade of dopamine D2 receptors in the associative striatum; however, there is little evidence for baseline overdrive of the dopamine system. Instead, the dopamine system is in a hyper-responsive state due to excessive drive by the hippocampus. This causes more dopamine neurons to be in a spontaneously active, hyper-responsive state. Antipsychotic drugs alleviate this by causing depolarization block, or excessive depolarization-induced dopamine neuron inactivation. Indeed, both first- and second-generation antipsychotic drugs cause depolar
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10

CLAVIN, PAUL, and FORMAN A. WILLIAMS. "Multidimensional stability analysis of gaseous detonations near Chapman–Jouguet conditions for small heat release." Journal of Fluid Mechanics 624 (April 10, 2009): 125–50. http://dx.doi.org/10.1017/s0022112008005387.

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Multidimensional instability of planar detonations, leading to cellular structures, is studied analytically near Chapman–Jouguet conditions, in the limit of small heat release, with small (Newtonian) differences between heat capacities, by using an expansion in a small parameter representing the ratio of the heat release to the thermal enthalpy of the fresh mixture. In this limit, the dynamics of detonations is governed by the interaction between the acoustic waves and the heat-release rate inside the inner detonation structure, the entropy–vorticity wave playing a negligible role at leading o
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11

Kaneko, Yoshiaki, Tadashi Nakajima, Tadanobu Irie, et al. "Mechanism of alternans of diastolic potential cycles during overdrive pacing of ventricular tachycardia." Journal of Arrhythmia 29, no. 1 (2013): 47–49. http://dx.doi.org/10.1016/j.joa.2012.09.003.

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12

Majumdar, Suchit, Krishna Kumar Mohanan Nair, Narayanan Namboodiri, and Ajitkumar Valaparambil. "Response to atrial overdrive pacing during narrow QRS tachycardia. What is the mechanism?" Indian Pacing and Electrophysiology Journal 20, no. 5 (2020): 203–5. http://dx.doi.org/10.1016/j.ipej.2020.07.002.

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13

Mohanan Nair, Krishna Kumar, Narayanan Namboodiri, Suji Karunakaran, Priya Giridhara, Abhilash Sreevilasam Pushpangadhan, and Ajitkumar Valaparambil. "Atrial overdrive pacing during wide QRS tachycardia with RBBB morphology. What is the mechanism?" Pacing and Clinical Electrophysiology 40, no. 8 (2017): 962–65. http://dx.doi.org/10.1111/pace.13134.

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14

Itoh, Taihei, Masaomi Kimura, Shogo Hamaura, et al. "Unusual response to overdrive pacing during a postinfarction ventricular tachycardia: What is the mechanism?" Journal of Cardiovascular Electrophysiology 31, no. 8 (2020): 2243–45. http://dx.doi.org/10.1111/jce.14639.

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15

Arias, Miguel A., and Ana M. Sánchez. "Response to overdrive pacing during regular paroxysmal supraventricular tachycardia: What is the tachycardia mechanism?" Heart Rhythm 4, no. 11 (2007): 1464–66. http://dx.doi.org/10.1016/j.hrthm.2007.02.016.

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16

Mohanan Nair, Krishna Kumar, Narayanan Namboodiri, Debasish Das, and Ajitkumar Valaparambil. "Interesting response of regular narrow QRS tachycardia to atrial overdrive pacing. What is the mechanism?" Pacing and Clinical Electrophysiology 42, no. 10 (2019): 1398–99. http://dx.doi.org/10.1111/pace.13788.

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17

Mohanan Nair, Krishna Kumar, Narayanan Namboodiri, Sreevilasam Pushpangadhan Abhilash, Mukund Prabhu, Debasish Das, and Ajitkumar Valaparambil. "Interesting response to ventricular overdrive pacing during regular narrow QRS tachycardia. What is the mechanism?" Indian Pacing and Electrophysiology Journal 20, no. 1 (2020): 39–40. http://dx.doi.org/10.1016/j.ipej.2019.12.003.

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18

Chen, Yan-song, I.-Ming Chen, and Tyng Liu. "A design approach for multi-configuration hybrid transmission mechanisms." Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering 234, no. 12 (2020): 2744–58. http://dx.doi.org/10.1177/0954407020924981.

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Several hybrid architectures have been widely used in hybrid electric vehicles. For example, power-split architecture brings seamless operation, while parallel architecture makes the internal combustion engine directly drive the wheel. To combine the advantages of various architectures, this study aims to develop a design approach to create a transmission mechanism that has multiple configurations and uses these configurations to achieve several hybrid architectures. First, this study standardized hybrid transmission mechanisms using the Function Power Graph; this powerful and intuitive tool i
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19

Garner, E. Michelle, Michael W. Kelly, and Dennis F. Thompson. "Tricyclic Antidepressant Withdrawal Syndrome." Annals of Pharmacotherapy 27, no. 9 (1993): 1068–72. http://dx.doi.org/10.1177/106002809302700912.

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OBJECTIVE: To examine the evidence pointing to a withdrawal syndrome associated with the discontinuation of tricyclic antidepressants (TCAs). DATA SOURCES: MEDLINE searches were conducted. References used in relevant articles were screened for additional published information. STUDY SELECTION: Emphasis was placed on human trials and individual case reports. DATA SYNTHESIS: Symptoms of gastrointestinal and somatic distress, sleep disturbance, and movement disorders and mania have been temporally linked to withdrawal of TCAs. Cholinergic and adrenergic overdrive after TCA discontinuation have be
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20

CHEN, Zhuoying, Huaimin CHEN, and Yongkang WANG. "Study on tolerance control of flying-wing layout vectored thrust UAV." Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University 40, no. 5 (2022): 990–96. http://dx.doi.org/10.1051/jnwpu/20224050990.

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The flying-wing layout vectored thrust UAV often uses multiple sets of aerodynamic rudder surfaces and vector nozzles to jointly generate the required control force and torque, which belongs to a typical overdrive system. Multiple sets of rudder surfaces give UAV a higher redundancy configuration, but also result in multiplying the rudder surface failure rate. Especially for the statically unstable flying-wing UAV in lateral direction, the moment imbalance caused by the failure of the executive rudder will seriously affect the flight safety. Therefore, this paper takes the failure of elevator
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Mohanan Nair, Krishna Kumar, Narayanan Namboodiri, and Ajitkumar Valaparambil. "Interesting response of wide QRS tachycardia with LBBB morphology to atrial overdrive pacing: What is the mechanism?" Pacing and Clinical Electrophysiology 43, no. 7 (2020): 754–55. http://dx.doi.org/10.1111/pace.13972.

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22

Agladze, Konstantin, Matthew W. Kay, Valentin Krinsky, and Narine Sarvazyan. "Interaction between spiral and paced waves in cardiac tissue." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 1 (2007): H503—H513. http://dx.doi.org/10.1152/ajpheart.01060.2006.

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For prevention of lethal arrhythmias, patients at risk receive implantable cardioverter-defibrillators, which use high-frequency antitachycardia pacing (ATP) to convert tachycardias to a normal rhythm. One of the suggested ATP mechanisms involves paced-induced drift of rotating waves followed by their collision with the boundary of excitable tissue. This study provides direct experimental evidence of this mechanism. In monolayers of neonatal rat cardiomyocytes in which rotating waves of activity were initiated by premature stimuli, we used the Ca2+-sensitive indicator fluo 4 to observe propaga
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23

ARIAS, MIGUEL A., ALBERTO PUCHOL, EDUARDO CASTELLANOS, MARTA PACHÓN, IRENE VALVERDE, and LUIS RODRÍGUEZ-PADIAL. "Atrial Overdrive Pacing Inducing QRS Complexes of Varying Duration in a Patient with Recurrent Syncope. What is the Mechanism?" Pacing and Clinical Electrophysiology 31, no. 2 (2008): 229–31. http://dx.doi.org/10.1111/j.1540-8159.2007.00973.x.

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24

Sun, Wei-Wei, Xue-Feng Zheng, Shuang Fan, et al. "Degradation mechanism of enhancement-mode AlGaN/GaN HEMTs using fluorine ion implantation under the on-state gate overdrive stress." Chinese Physics B 24, no. 1 (2015): 017303. http://dx.doi.org/10.1088/1674-1056/24/1/017303.

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25

Maruyama, Mitsunori, Seiji Takatsuki, and Wataru Shimizu. "Disproportionate delay in ventricular capture during atrial overdrive pacing in a long RP supraventricular tachycardia: What is the mechanism?" Heart Rhythm 13, no. 7 (2016): 1563–64. http://dx.doi.org/10.1016/j.hrthm.2016.03.052.

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26

Rengo, Giuseppe, Dario Leosco, Carmela Zincarelli, et al. "Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure." American Journal of Physiology-Heart and Circulatory Physiology 298, no. 6 (2010): H2032—H2038. http://dx.doi.org/10.1152/ajpheart.00702.2009.

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Exercise training has been reported to exert beneficial effects on cardiac function and to reduce morbidity and mortality of chronic heart failure (HF). Augmented sympathetic nervous system (SNS) activity, leading to elevated circulating catecholamine (CA) levels, is a hallmark of chronic HF that significantly aggravates this disease. Exercise training has been shown to also reduce SNS overactivity in HF, but the underlying molecular mechanism(s) remain unidentified. We recently reported that adrenal G protein-coupled receptor kinase-2 (GRK2), an enzyme that regulates the sympathoinhibitory α2
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Mohanan Nair, Krishna Kumar, Narayanan Namboodiri, Hiren Kevadiya, Das Debasish, and Ajitkumar Valaparambil. "Response of narrow QRS tachycardia in a patient with surgical closure of atrial septal defect to atrial overdrive pacing: What is the mechanism?" Journal of Cardiovascular Electrophysiology 30, no. 10 (2019): 2130–33. http://dx.doi.org/10.1111/jce.14099.

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28

Viamonte, V. A., and M. R. Rosen. "Premature escape beats induced by overdrive pacing in canine Purkinje fibers. Evidence for the role of normal automaticity as an underlying cellular mechanism." Circulation 82, no. 1 (1990): 234–43. http://dx.doi.org/10.1161/01.cir.82.1.234.

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29

Nadaud, Sophie, Mathilde Flamant, Wilfried Le Goff, Elise Balse, and Catherine Pavoine. "Transcriptomic and Lipidomic Mapping of Macrophages in the Hub of Chronic Beta-Adrenergic-Stimulation Unravels Hypertrophy-, Proliferation-, and Lipid Metabolism-Related Genes as Novel Potential Markers of Early Hypertrophy or Heart Failure." Biomedicines 10, no. 2 (2022): 221. http://dx.doi.org/10.3390/biomedicines10020221.

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Sympathetic nervous system overdrive with chronic release of catecholamines is the most important neurohormonal mechanism activated to maintain cardiac output in response to heart stress. Beta-adrenergic signaling behaves first as a compensatory pathway improving cardiac contractility and maladaptive remodeling but becomes dysfunctional leading to pathological hypertrophy and heart failure (HF). Cardiac remodeling is a complex inflammatory syndrome where macrophages play a determinant role. This study aimed at characterizing the temporal transcriptomic evolution of cardiac macrophages in mice
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30

Lee, H. I., and D. S. Stewart. "Calculation of linear detonation instability: one-dimensional instability of plane detonation." Journal of Fluid Mechanics 216 (July 1990): 103–32. http://dx.doi.org/10.1017/s0022112090000362.

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The detonation stability problem is studied by a normal mode approach which greatly simplifies the calculation of linear instability of detonation in contrast to the Laplace transform procedure used by Erpenbeck. The method of solution, for an arbitrary parameter set, is a shooting method which can be automated to generate easily the required information about instability. The condition on the perturbations applied at the end of the reaction zone is shown to be interpreted as either a boundedness condition or an acoustic radiation condition. Continuous and numerically exact neutral stability c
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Bruno, Rosa Maria, and Lorenzo Ghiadoni. "Polyphenols, Antioxidants and the Sympathetic Nervous System." Current Pharmaceutical Design 24, no. 2 (2018): 130–39. http://dx.doi.org/10.2174/1381612823666171114170642.

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Background: A high dietary intake of polyphenols has been associated with a reduced cardiovascular mortality, due to their antioxidant properties. However, growing evidence suggests that counteracting oxidative stress in cardiovascular disease might also reduce sympathetic nervous system overactivity. Methods: This article reviews the most commonly used techniques to measure sympathetic activity in humans; the role of sympathetic activation in the pathophysiology of cardiovascular diseases; current evidence demonstrating that oxidative stress is involved in the regulation of sympathetic activi
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Gronda, E., V. Dusi, E. D’Elia, M. Iacoviello, E. Benvenuto, and E. Vanoli. "Sympathetic activation in heart failure." European Heart Journal Supplements 24, Supplement_E (2022): E4—E11. http://dx.doi.org/10.1093/eurheartjsupp/suac030.

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Abstract Sympathetic activation has been long appreciated exclusively as a fundamental compensatory mechanism of the failing heart and, thus, welcome and to be supported. In the initial clinical phases of heart failure (HF), the sympathetic nervous system overdrive plays a compensatory function aimed at maintaining an adequate cardiac output despite the inotropic dysfunction affecting the myocardium. However, when the sympathetic reflex response is exaggerated it triggers a sequence of unfavourable remodelling processes causing a further contractile deterioration that unleashes major adverse c
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Lin, Chun-Yu, Shih-Han Kao, Ling-Chien Hung, et al. "Lipopolysaccharide-Induced Nitric Oxide and Prostaglandin E2 Production Is Inhibited by Tellimagrandin II in Mouse and Human Macrophages." Life 11, no. 5 (2021): 411. http://dx.doi.org/10.3390/life11050411.

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Sepsis develops from a serious microbial infection that causes the immune system to go into overdrive. The major microorganisms that induce sepsis are Gram-negative bacteria with lipopolysaccharide (LPS) in their cell walls. Nitric oxide (NO) and cyclooxygenase-2 (COX-2) are the key factors involved in the LPS-induced pro-inflammatory process. This study aimed to evaluate the effects of polyphenol Tellimagrandin II (TGII) on anti-inflammatory activity and its underlying basic mechanism in murine macrophage cell line RAW 264.7 and human monocyte-derived macrophages. Macrophages with more than 9
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34

Cerghit, Andreea Paler, Amalia Făgărășan, Iolanda Muntean, et al. "Atrial Flutter in a Newborn: a Case Report." Journal Of Cardiovascular Emergencies 6, no. 3 (2020): 67–71. http://dx.doi.org/10.2478/jce-2020-0010.

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AbstractIntroduction: The incidence of cardiac arrhythmia is approximately 1% in the neonatal period and 1–3% in late pregnancy. Atrial flutter (AF), a rhythm disorder based on the mechanism of reentry, represents approximately 32% of all neonatal cardiac arrhythmias. In the majority of cases, the flutter is converted to sinus rhythm using antiarrhythmic drugs, transesophageal overdrive pacing, or synchronized electrical cardioversion.Case presentation: We present a case of a born on term, female infant who was noted to be tachycardic on the fetal monitor. Clinical examination revealed tachypn
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Hohberger, Bettina, Harald Prüss, Christian Mardin, Robert Lämmer, Johannes Müller, and Gerd Wallukat. "Glaucoma and Alzheimer: Neurodegenerative disorders show an adrenergic dysbalance." PLOS ONE 17, no. 10 (2022): e0272811. http://dx.doi.org/10.1371/journal.pone.0272811.

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Glaucoma disease is characterized by an increased intraocular pressure (IOP), glaucomatous alterations of the optic disc and corresponding visual field defects. Even lowering the main risk factor IOP until an individual target level does not prevent this neurodegenerative disorder from proceeding. Several autoimmune mechanisms were discovered, partly showing a functionality. One of these autoimmune phenomena targets the ß2-adrenergic receptor (ß2-AR; i.e. agonistic autoantibodies; ß2-agAAb) and is linked to an elevated IOP and an impaired retinal microcirculation. As neurodegenerative disorder
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36

Dai, Jian, and Linyuan Peng. "Numerical Investigation on Detonation Initiation and Propagation with a Symmetric-Jet in Supersonic Combustible Gas." Aerospace 9, no. 9 (2022): 501. http://dx.doi.org/10.3390/aerospace9090501.

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In this study, supersonic gaseous detonation initiation and propagation by single- and symmetric-jets are compared, and the effects of symmetric-jets of different intensities on the detonation are further investigated to obtain a more comprehensive understanding of the initiation mechanism of hot jet in supersonic mixtures. The two-dimensional reactive Navier–Stokes equations, together with a one-step Arrhenius chemistry model, are adopted to analyze the flow field structure. The results show that the bow shocks induced by symmetric-jets interacting with each other will achieve local detonatio
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Guild, Sarah-Jane, Utkarsh A. Saxena, Fiona D. McBryde, Simon C. Malpas, and Rohit Ramchandra. "Intracranial pressure influences the level of sympathetic tone." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 315, no. 5 (2018): R1049—R1053. http://dx.doi.org/10.1152/ajpregu.00183.2018.

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Sympathetic overdrive is associated with many diseases, but its origin remains an enigma. An emerging hypothesis in the development of cardiovascular disease is that the brain puts the utmost priority on maintaining its own blood supply; even if this comes at the “cost” of high blood pressure to the rest of the body. A critical step in making a causative link between reduced brain blood flow and cardiovascular disease is how changes in cerebral perfusion affect the sympathetic nervous system. A direct link between decreases in cerebral perfusion pressure and sympathetic tone generation in a co
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SHORT, MARK, and D. SCOTT STEWART. "Cellular detonation stability. Part 1. A normal-mode linear analysis." Journal of Fluid Mechanics 368 (August 10, 1998): 229–62. http://dx.doi.org/10.1017/s0022112098001682.

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A detailed investigation of the hydrodynamic stability to transverse linear disturbances of a steady, one-dimensional detonation in an ideal gas undergoing an irreversible, unimolecular reaction with an Arrhenius rate constant is conducted via a normal-mode analysis. The method of solution is an iterative shooting technique which integrates between the detonation shock and the reaction equilibrium point. Variations in the disturbance growth rates and frequencies with transverse wavenumber, together with two-dimensional neutral stability curves and boundaries for all unstable low- and higher fr
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Obokata, Masaru, Tatsuya Iso, Yoshiaki Ohyama, et al. "Early increase in serum fatty acid binding protein 4 levels in patients with acute myocardial infarction." European Heart Journal: Acute Cardiovascular Care 7, no. 6 (2016): 561–69. http://dx.doi.org/10.1177/2048872616683635.

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Background: Acute myocardial infarction (AMI) induces marked activation of the sympathetic nervous system. Fatty acid binding protein 4 (FABP4) is not only an intracellular protein, but also a secreted adipokine that contributes to obesity-related metabolic complications. Here, we examined the role of serum FABP4 as a pathophysiological marker in patients with AMI. Methods and results: We studied 106 patients presenting to the emergency unit with a final diagnosis of AMI, including 12 patients resuscitated from out-of-hospital cardiac arrest (OHCA) caused by ventricular fibrillation. FABP4 lev
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40

Timbol, Edgar Wilson G., and Giselle G. Gervacio. "Inducible Focal Atrial Tachycardia of Coronary Sinus Origin Masquerading as Ventricular Tachycardia." Philippine Journal of Cardiology 42, no. 1 (2014): 1–5. http://dx.doi.org/10.69944/pjc.6b3817b183.

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CASE: This is the case of a 35-year old male physician presenting with a 12-year history of palpitations despite oral metoprolol. He had reversible left hemiparesis with right hemispheric lacunar infarctions on computerized tomography scan. The 12-lead electrocardiogram (ECG) recorded during an episode of palpitations revealed wide QRS (0.16 s) tachycardia (heart rate=214 beats per minute) with left bundle branch block (LBBB) QRS morphology; no identifiable P waves; QS pattern in leads V1 to V4; RS pattern in leads V5 and V6; and a QRS axis at -1300. There were no AV dissociation; fusion and c
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Grace, *Anthony A., and Daniela Uliana. "POSTPUBERTAL STRESS SELECTIVELY ACTIVATES DOPAMINE NEURONS PROJECTING TO THE VENTRAL STRIATUM VIA DISRUPTION OF RETICULAR THALAMIC NUCLEUS-NUCLEUS REUNIENS-VENTRAL HIPPOCAMPAL ACTIVITY." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i28—i29. https://doi.org/10.1093/ijnp/pyae059.050.

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Abstract Background Stress is a major risk factor for psychiatric disorders, particularly when occuring during the sensitive period of adolescence. We showed previously that male rats exposed to major stressors during prepuberty exhibit amygdala-driven loss of parvalbumin neurons in the ventral hippocampus, hippocampal hyperactivity, and an increase in ventral tegmental area (VTA) dopamine (DA) neuron activity. In contrast, we now find that female rats are resilient to the effects of prepubertal stress, but are uniquely sensitive to postpubertal (PostP) stress that impacts the system via a uni
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Clavin, Paul, and Longting He. "Stability and nonlinear dynamics of one-dimensional overdriven detonations in gases." Journal of Fluid Mechanics 306 (January 10, 1996): 353–78. http://dx.doi.org/10.1017/s0022112096001334.

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The purpose of this analytical work is twofold: first, to clarify the physical mechanisms triggering the one-dimensional instabilities of plane detonations in gases; secondly to provide a nonlinear description of the longitudinal dynamics valid even far from the bifurcation. The fluctuations of the rate of heat release result from the temperature fluctuations of the shocked gas with a time delay introduced by the propagation of entropy waves. The motion of the shock is governed by a mass conservation resulting from the gas expansion across the reaction zone whose position fluctuates relative t
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43

Kunysz, A., L. Glass, and A. Shrier. "Overdrive suppression of spontaneously beating chick heart cell aggregates: experiment and theory." American Journal of Physiology-Heart and Circulatory Physiology 269, no. 3 (1995): H1153—H1164. http://dx.doi.org/10.1152/ajpheart.1995.269.3.h1153.

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In spontaneously beating chick heart cell aggregates, sustained periodic stimulation at a rate faster than the intrinsic frequency is generally followed by a transient slowing of the automatic rhythm called "overdrive suppression." We characterize the qualitative aspects of overdrive suppression using three sets of experimental protocols: 1) stimulation at a fixed frequency with various numbers of stimuli, 2) stimulation at different frequencies, 3) stimulation with different intensities. We develop a mathematical model based on a system of nonlinear ordinary differential equations to account
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44

Perina, Welder, Joao Martino, and Paula Agopian. "(Digital Presentation) Analysis of MIS-HEMT Kink Effect in Saturation Region." ECS Meeting Abstracts MA2023-01, no. 33 (2023): 1873. http://dx.doi.org/10.1149/ma2023-01331873mtgabs.

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The High Electron Mobility Transistor (HEMT) has been widely used in the field of power electronics and high frequency operation since 1983 (1), while presenting a simple circuit design for analog applications (2, 3), and for extreme harsh environments as well (3, 4). However, HEMTs presents a problem with gate leakage and current collapse which can be solved by introducing an insulator between the gate and semiconductor while maintaining the high performance, hence the Metal Insulator Semiconductor High Electron Mobility Transistor (MIS-HEMT) appears as a solution. The AlGaN/GaN heterostructu
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45

Krykhtin, Yu I., and V. I. Karlov. "Analyzing Operations of a Torsion Shaft Installed in an ICE and in an Overdrive Gearbox at the Inlet of a Transmission Torque Converter and Turning Mechanism Installed in a Lightweight Caterpillar Machine to Improve Reliability." Journal of Machinery Manufacture and Reliability 50, no. 4 (2021): 357–63. http://dx.doi.org/10.3103/s1052618821040051.

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46

SHORT, MARK, and D. SCOTT STEWART. "Low-frequency two-dimensional linear instability of plane detonation." Journal of Fluid Mechanics 340 (June 10, 1997): 249–95. http://dx.doi.org/10.1017/s0022112097005120.

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An analytical dispersion relation describing the linear stability of a plane detonation wave to low-frequency two-dimensional disturbances with arbitrary wavenumbers is derived using a normal mode approach and a combination of high activation energy and Newtonian limit asymptotics, where the ratio of specific heats γ→1. The reaction chemistry is characterized by one-step Arrhenius kinetics. The analysis assumes a large activation energy in the plane steady-state detonation wave and a characteristic linear disturbance wavelength which is longer than the fire-zone thickness. Newtonian limit asym
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47

Habuchi, Yoshizumi, Akihiko Miyakawa, Masao Nishimura, and Yoshio Watanabe. "-175-IONIC MECHANISMS UNDERLYING OVERDRIVE SUPPRESSION OF THE RABBIT SINUS NODE." Japanese Circulation Journal 50, no. 6 (1986): 510. http://dx.doi.org/10.1253/jcj.50.510_3.

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48

Grande, Mike. "Understanding Thermal Overdrive in Industrial Ovens." AM&P Technical Articles 175, no. 6 (2017): 82–83. http://dx.doi.org/10.31399/asm.amp.2017-06.p082.

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49

Hamada, Toru, Yuichi Nakamura, and Shigeru Itoh. "The Performance of Pressure Vessel Using Concentric Double Cylindrical High Explosive." Journal of Pressure Vessel Technology 126, no. 4 (2004): 409–13. http://dx.doi.org/10.1115/1.1804201.

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The detonation pressure from the steady detonation of high explosives is a characteristic. Nevertheless, in materials processing using high explosives, there are cases when the detonation pressure does not match the intended pressure. In this investigation, as a new method of generating the overdriven detonation effectively, a double cylindrical high explosive set up using two kinds of explosives was developed, and its basic performance is analyzed. The concentric double cylindrical high explosive set up was composed of a high velocity explosive and a low velocity explosive, and the overdriven
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50

Ohmori, Kenji, Kenji Shiraishi, and Keisaku Yamada. "Influences of Carrier Transport on Drain-Current Variability of MOSFETs." Key Engineering Materials 470 (February 2011): 184–87. http://dx.doi.org/10.4028/www.scientific.net/kem.470.184.

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We have investigated the static variability of p-MOSFETs by evaluating the drain current under various conditions of gate and drain voltages. The value of drain current variability (σId/Id) is proportional to (LW)-1/2 before the short channel effect appears, being similar to that of Vt variability. The magnitude of σId/Id decreases as the gate overdrive (Vg-Vt) decreases, and it is classified into two regimes that correspond to the carrier conduction mechanisms, namely diffusion and drift transports. This result strongly suggests that the dominant factors for determining σId/Id values are rela
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