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1

Cohen, Jessica, Liron Sinvani, Jason Wang, et al. "Warfarin Quality Metrics for Hospitalized Older Adults." TH Open 02, no. 03 (2018): e242-e249. http://dx.doi.org/10.1055/s-0038-1667138.

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Background Warfarin's adverse drug events are dangerous, common, and costly. While outpatient warfarin management tools exist, there is a dearth of guidance for inpatients. Objectives We sought to describe a health system's chronic warfarin quality metrics in older inpatients, defined by international normalized ratio (INR) control, explore associations between INR overshoots and clinical outcomes, and identify factors associated with overshoots. Patients/Methods Data on patients 65 years and older who were prescribed chronic warfarin and admitted during January 1, 2014, to June 30, 2016, were
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2

Dauhut, Thibaut, Jean-Pierre Chaboureau, Peter H. Haynes, and Todd P. Lane. "The Mechanisms Leading to a Stratospheric Hydration by Overshooting Convection." Journal of the Atmospheric Sciences 75, no. 12 (2018): 4383–98. http://dx.doi.org/10.1175/jas-d-18-0176.1.

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Abstract Overshoots are convective air parcels that rise beyond their level of neutral buoyancy. A giga-large-eddy simulation (100-m cubic resolution) of “Hector the Convector,” a deep convective system that regularly forms in northern Australia, is analyzed to identify overshoots and quantify the effect of hydration of the stratosphere. In the simulation, 1507 individual overshoots were identified, and 46 of them were tracked over more than 10 min. Hydration of the stratosphere occurs through a sequence of mechanisms: overshoot penetration into the stratosphere, followed by entrainment of str
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3

Arens, J., J. Stabel, and U. Heinemann. "Pharmacological properties of excitatory amino acid induced changes in extracellular calcium concentration in rat hippocampal slices." Canadian Journal of Physiology and Pharmacology 70, S1 (1992): S194—S205. http://dx.doi.org/10.1139/y92-263.

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We have studied extracellular ionic changes induced by iontophoretic application of excitatory amino acids in rat hippocampal slices. In contrast to kinetics of changes in [Ca2+]o, kinetics of changes in [K+]o, [Na+]o, [Cl−]o as well as in extracellular space size were comparable for different glutamate receptor agonists. Thus, α-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA), quisqualate (quis), and kainate caused reductions in [Ca2+]o followed by an increase of [Ca2+]o above baseline, whereas glutamate, aspartate, N-methyl-D-aspartate (NMDA), and DL-homocysteic acid caused only reduc
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4

Mellott, M. M., and W. A. Livesey. "Shock overshoots revisited." Journal of Geophysical Research 92, A12 (1987): 13661. http://dx.doi.org/10.1029/ja092ia12p13661.

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5

Doney, R. A., and P. S. Griffin. "Overshoots over curved boundaries." Advances in Applied Probability 35, no. 02 (2003): 417–48. http://dx.doi.org/10.1017/s0001867800012325.

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We consider the asymptotic behaviour of a random walk when it exits from a symmetric region of the form {(x, n) :|x| ≤ rn b } as r → ∞. In order to be sure that this actually occurs, we treat only the case where the power b lies in the interval [0,½), and we further assume a condition that prevents the probability of exiting at either boundary tending to 0. Under these restrictions we establish necessary and sufficient conditions for the pth moment of the overshoot to be O(r q ), and for the overshoot to be tight, as r → ∞.
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6

Filippov, Leonid K., and Nadezhda L. Filippova. "Overshoots of Adsorption Kinetics." Journal of Colloid and Interface Science 178, no. 2 (1996): 571–80. http://dx.doi.org/10.1006/jcis.1996.0153.

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7

Doney, R. A., and P. S. Griffin. "Overshoots over curved boundaries." Advances in Applied Probability 35, no. 2 (2003): 417–48. http://dx.doi.org/10.1239/aap/1051201655.

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We consider the asymptotic behaviour of a random walk when it exits from a symmetric region of the form {(x, n) :|x| ≤ rnb} as r → ∞. In order to be sure that this actually occurs, we treat only the case where the power b lies in the interval [0,½), and we further assume a condition that prevents the probability of exiting at either boundary tending to 0. Under these restrictions we establish necessary and sufficient conditions for the pth moment of the overshoot to be O(rq), and for the overshoot to be tight, as r → ∞.
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8

Johnson, Harry E., Stephen J. Clarson, and Steve Granick. "Overshoots as polymers adsorb." Polymer 34, no. 9 (1993): 1960–62. http://dx.doi.org/10.1016/0032-3861(93)90443-e.

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9

Koncz, Viktória, Zoltán Noszticzius, and Kristóf Kály-Kullai. "Transient Response of the Acid-base Diode for Polarity Change." Periodica Polytechnica Chemical Engineering 65, no. 4 (2021): 559–66. http://dx.doi.org/10.3311/ppch.17821.

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An application of the so-called acid-base diode would be the sensitive detection of nonhydrogen cations in an acidic medium based on salt-effects. For diode purposes different connecting elements between the acidic and aqueous reservoirs of the diode were developed, namely a polyvinyl alcohol (PVA) hydrogel cylinder, and a polyvinyl butyral (PVB) membrane. During the measurement of the voltage – current characteristic (VCC) of the diode, it was found, that in the case of PVA gel cylinder an overshoot (a local maximum followed by a local minimum) appeared in the time vs. current curve, while th
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10

Kump, David S., Matthew J. Laye, and Frank W. Booth. "Increased mitochondrial glycerol-3-phosphate acyltransferase protein and enzyme activity in rat epididymal fat upon cessation of wheel running." American Journal of Physiology-Endocrinology and Metabolism 290, no. 3 (2006): E480—E489. http://dx.doi.org/10.1152/ajpendo.00321.2005.

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Triacylglycerol synthesis in rat epididymal fat overshoots sedentary levels at 10, 29, and 53 h of physical inactivity after 21 days of wheel running. The purposes of the present study were to determine 1) whether this effect is also observed after an acute bout of physical activity and 2) what enzymatic changes might contribute to this effect. We show that more than one bout of physical activity, such as that which occurs with 21 days of wheel running, is necessary for palmitic acid incorporation into triacylglyceride (triglyceride synthesis) to overshoot sedentary values, which suggests that
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11

Doney, R. A., and P. S. Griffin. "Overshoots over curved boundaries. II." Advances in Applied Probability 36, no. 04 (2004): 1148–74. http://dx.doi.org/10.1017/s0001867800013343.

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We continue the study of the asymptotic behaviour of a random walk when it exits from a symmetric region of the form {(x, n): |x| ≤ rn b } as r → ∞ which was begun in Part I of this work. In contrast to that paper, we are interested in the case where the probability of exiting at the upper boundary tends to 1. In this scenario we treat the case where the power b lies in the interval [0, 1), and we establish necessary and sufficient conditions for the overshoot to be relatively stable in probability (except for the case ), and for the pth moment of the overshoot to be O(r q ) as r → ∞.
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12

Banks, Michael. "Japanese mission overshoots Venus orbit." Physics World 24, no. 01 (2011): 9. http://dx.doi.org/10.1088/2058-7058/24/01/15.

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13

Doney, R. A., and P. S. Griffin. "Overshoots over curved boundaries. II." Advances in Applied Probability 36, no. 4 (2004): 1148–74. http://dx.doi.org/10.1239/aap/1103662961.

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We continue the study of the asymptotic behaviour of a random walk when it exits from a symmetric region of the form {(x, n): |x| ≤ rnb} as r → ∞ which was begun in Part I of this work. In contrast to that paper, we are interested in the case where the probability of exiting at the upper boundary tends to 1. In this scenario we treat the case where the power b lies in the interval [0, 1), and we establish necessary and sufficient conditions for the overshoot to be relatively stable in probability (except for the case ), and for the pth moment of the overshoot to be O(rq) as r → ∞.
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14

KOBAYASHI, Fuminori. "Time-Optimal PLL without Response Overshoots." Transactions of the Society of Instrument and Control Engineers 21, no. 4 (1985): 397–402. http://dx.doi.org/10.9746/sicetr1965.21.397.

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15

Poole, Robert J., and Manuel A. Alves. "Velocity overshoots in gradual contraction flows." Journal of Non-Newtonian Fluid Mechanics 160, no. 1 (2009): 47–54. http://dx.doi.org/10.1016/j.jnnfm.2009.03.005.

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16

Doney, R. A., and A. E. Kyprianou. "Overshoots and undershoots of Lévy processes." Annals of Applied Probability 16, no. 1 (2006): 91–106. http://dx.doi.org/10.1214/105051605000000647.

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17

Cornille, Henri. "Temperature overshoots for multispeed discrete Boltzmann models." Physics Letters A 154, no. 7-8 (1991): 339–45. http://dx.doi.org/10.1016/0375-9601(91)90029-8.

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18

Narmadha, T. Velayudham, Chackaravarthy Baskaran, and K. Sivakumar. "Comparison of Performance Measures of Speed Control for a DC Motor Using Hybrid Intelligent Controller and Optimal LQR." Applied Mechanics and Materials 622 (August 2014): 23–31. http://dx.doi.org/10.4028/www.scientific.net/amm.622.23.

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-In this paper , performance of fuzzy PD , fuzzy PI , fuzzy PD+I , fuzzy PID controllers are evaluated and compared. This paper also describes the speed control based on Linear Quadratic Regulator (LQR) technique. The comparison is based on their ability of controlling the speed of DC motor, which merely focuses on performance index of the controllers, and also time domain specifications such as rise time, settling time and peak overshoot. The controller is modelled using MATLAB software, the simulation results shows that the fuzzy PID controllers are the best performing candidates in all aspe
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19

Atia, Khaled R., and M. P. Cartmell. "A New Methodology for Designing PD Controllers." Robotica 19, no. 3 (2001): 267–73. http://dx.doi.org/10.1017/s0263574700003088.

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It is known that it is impossible to select fixed gains for a PD controller that will critically damp the response to disturbances for all configurations of a given robot system. Because of this the potential for overshoot is always present and cannot be avoided unless the system is severely overdamped. This is not necessarily a practical solution and can be an economically unacceptable approach. On the other hand, however, if overshoot is permissible to some degree for some systems in the case of conventional Serial robots it is still prohibited in the case of Parallel robots as it may easily
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20

Cao, Hongli, Ye He, Xiaoan Chen, and Xue Zhao. "Smooth adaptive hybrid impedance control for robotic contact force tracking in dynamic environments." Industrial Robot: the international journal of robotics research and application 47, no. 2 (2020): 231–42. http://dx.doi.org/10.1108/ir-09-2019-0191.

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Purpose The purpose of this paper is to take transient contact force response, overshoots and steady-state force tracking error problems into account to form an excellent force controller. Design/methodology/approach The basic impedance function with a pre-PID tuner is designed to improve the force response. A dynamic adaptive adjustment function that combines the advantages of hybrid impedance and adaptive hybrid impedance control is presented to achieve both force overshoots suppressing and tracking ability. Findings The introduced pre-PID tuner impedance function can achieve more than the p
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21

Bertoin, Jean. "On overshoots and hitting times for random walks." Journal of Applied Probability 36, no. 02 (1999): 593–600. http://dx.doi.org/10.1017/s0021900200017344.

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Consider an oscillating integer valued random walk up to the first hitting time of some fixed integer x > 0. Suppose there is a fee to be paid each time the random walk crosses the level x, and that the amount corresponds to the overshoot. We determine the distribution of the sum of these fees in terms of the renewal functions of the ascending and descending ladder heights. The proof is based on the observation that some path transformation of the random walk enables us to translate the problem in terms of the intersection of certain regenerative sets.
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22

Tátrallyay, M., G. Gévai, I. Apáthy, et al. "Magnetic field overshoots in the Martian bow shock." Journal of Geophysical Research: Space Physics 102, A2 (1997): 2157–63. http://dx.doi.org/10.1029/96ja00073.

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23

Brooks, F. J., and A. E. Carlsson. "Actin polymerization overshoots induced by plus-end capping." Physical Biology 7, no. 1 (2010): 016008. http://dx.doi.org/10.1088/1478-3975/7/1/016008.

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24

Bertoin, Jean. "On overshoots and hitting times for random walks." Journal of Applied Probability 36, no. 2 (1999): 593–600. http://dx.doi.org/10.1239/jap/1032374474.

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Consider an oscillating integer valued random walk up to the first hitting time of some fixed integer x > 0. Suppose there is a fee to be paid each time the random walk crosses the level x, and that the amount corresponds to the overshoot. We determine the distribution of the sum of these fees in terms of the renewal functions of the ascending and descending ladder heights. The proof is based on the observation that some path transformation of the random walk enables us to translate the problem in terms of the intersection of certain regenerative sets.
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25

Zhang, Huaibao, and Fan Zhang. "On the numerical overshoots of shock‐capturing schemes." International Journal for Numerical Methods in Fluids 93, no. 10 (2021): 3151–59. http://dx.doi.org/10.1002/fld.5023.

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26

DiFranco, Marino, and Julio L. Vergara. "The Na conductance in the sarcolemma and the transverse tubular system membranes of mammalian skeletal muscle fibers." Journal of General Physiology 138, no. 4 (2011): 393–419. http://dx.doi.org/10.1085/jgp.201110682.

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Na (and Li) currents and fluorescence transients were recorded simultaneously under voltage-clamp conditions from mouse flexor digitorum brevis fibers stained with the potentiometric dye di-8-ANEPPS to investigate the distribution of Na channels between the surface and transverse tubular system (TTS) membranes. In fibers rendered electrically passive, voltage pulses resulted in step-like fluorescence changes that were used to calibrate the dye response. The effects of Na channel activation on the TTS voltage were investigated using Li, instead of Na, because di-8-ANEPPS transients show anomali
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27

Sentjabrskaja, T., M. Hermes, W. C. K. Poon, et al. "Transient dynamics during stress overshoots in binary colloidal glasses." Soft Matter 10, no. 34 (2014): 6546–55. http://dx.doi.org/10.1039/c4sm00577e.

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Caging transitions determine changes in the yield strain, the magnitude of the stress overshoots and the transient single-particle dynamics of binary glasses under an imposed shear rate of deformation.
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28

Krishna, Rajamani. "Tracing the origins of transient overshoots for binary mixture diffusion in microporous crystalline materials." Physical Chemistry Chemical Physics 18, no. 23 (2016): 15482–95. http://dx.doi.org/10.1039/c6cp00132g.

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29

Letwimolnun, W., B. Vergnes, G. Ausias, and P. J. Carreau. "Stress overshoots of organoclay nanocomposites in transient shear flow." Journal of Non-Newtonian Fluid Mechanics 141, no. 2-3 (2007): 167–79. http://dx.doi.org/10.1016/j.jnnfm.2006.11.003.

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30

Vesipa, Riccardo, and Luca Ridolfi. "Overshoots in the water-level control of hydropower plants." Renewable Energy 131 (February 2019): 800–810. http://dx.doi.org/10.1016/j.renene.2018.07.090.

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31

Borodkova, N. L., O. V. Sapunova, V. G. Eselevich, G. N. Zastenker, and Yu I. Yermolaev. "Comparison of Magnetic and Plasma Overshoots of Interplanetary Shocks." Cosmic Research 58, no. 6 (2020): 450–59. http://dx.doi.org/10.1134/s0010952520060015.

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32

Hawke, L. G. D., Q. Huang, O. Hassager, and D. J. Read. "Modifying the pom-pom model for extensional viscosity overshoots." Journal of Rheology 59, no. 4 (2015): 995–1017. http://dx.doi.org/10.1122/1.4922060.

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33

Robinett, Joel C., Laurin M. Hanft, and Kerry S. McDonald. "Step Stretches and Shortenings Elicit Similar Transient Force Overshoots." Biophysical Journal 118, no. 3 (2020): 279a. http://dx.doi.org/10.1016/j.bpj.2019.11.1595.

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34

Cahill, Alison G., Anthony Odibo, Kimberly Roehl, and George Macones. "612: Slow returns and overshoots: do they mean anything?" American Journal of Obstetrics and Gynecology 206, no. 1 (2012): S275. http://dx.doi.org/10.1016/j.ajog.2011.10.630.

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35

RASTOGI, A., and R. K. GUPTA. "PERFORMANCE OF SHORT JOURNAL BEARINGS: ROLE OF STRESS OVERSHOOTS." Chemical Engineering Communications 156, no. 1 (1997): 75–88. http://dx.doi.org/10.1080/00986449708936670.

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36

Yang and Choi. "Power Efficiency Improvement of Three-Phase Split-Output Inverter Using Magnetically Coupled Inductor Switching." Electronics 8, no. 9 (2019): 969. http://dx.doi.org/10.3390/electronics8090969.

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The conventional three-phase split-output inverter (SOI) has been used for grid-connected applications because it does not require dead time and has no shoot-through problems. Recently, the conventional inverter uses the silicon carbide (SiC) schottky diodes for the freewheeling diodes because of its no reverse-recovery problem. Nevertheless, in a practical design, the SiC schottky diodes suffer from current overshoots and voltage oscillations. These overshoots and oscillations result in switching-power losses, decreasing the power efficiency of the inverter. To alleviate this drawback, we pre
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37

Li, Jian Wen, Bing Xin Zhang, and Jian Ping Xing. "An Improved Compensation Alternating Voltage Regulator Using Bidirectional-Thyristor Bridge." Applied Mechanics and Materials 148-149 (December 2011): 556–60. http://dx.doi.org/10.4028/www.scientific.net/amm.148-149.556.

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High power alternating voltage regulators commonly use few isolation transformers to compensate the variation of the input voltage or output load, and use a bidirectional-thyistor bridge with multiple arms to adjust the direction and magnitude of the compensation voltage . This kind of voltage regulator has been widely used for its simplicity, low cost, and high efficiency. But its compensation voltage adjustment process often accompanies with deep output voltage sags or high input current overshoots. An improved topology is proposed---adding one more circuit unit to help the adjustment of com
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38

Nakayama, Hideaki, Curtis A. Smith, Joshua R. Rodman, James B. Skatrud, and Jerome A. Dempsey. "Carotid body denervation eliminates apnea in response to transient hypocapnia." Journal of Applied Physiology 94, no. 1 (2003): 155–64. http://dx.doi.org/10.1152/japplphysiol.00722.2002.

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We determined the effects on breathing of transient ventilatory overshoots and concomitant hypocapnia, as produced by pressure support mechanical ventilation (PSV), in intact and carotid body chemoreceptor denervated (CBX) sleeping dogs. In the intact dog, PSV-induced transient increases in tidal volume and hypocapnia caused apnea within 10–11 s, followed by repetitive two-breath clusters separated by apneas, i.e., periodic breathing (PB). After CBX, significant expiratory time prolongation did not occur until after 30 s of PSV-induced hypocapnia, and PB never occurred. Average apneas of 8.4 ±
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39

Monjezi, Behnam, and Hamidreza Heidari. "Active vibration control of rotor-bearing system by virtual dynamic absorber." European Physical Journal Applied Physics 86, no. 3 (2019): 30901. http://dx.doi.org/10.1051/epjap/2019190073.

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The main sources of the vibration in rotor dynamic systems are unbalanced masses and manufacturing defects of bearings used in the rotor system. In this study, magnetic absorber as a new method brings the rotor system out of resonance state by applying a dynamic absorber system force and creating two new natural frequencies. This study virtually reconstructed magnetic absorber controller software as a combined active and passive dynamic absorber to reduce vibration amplitude, efficiently. In this approach, combined routes are defined for the rotor frequency response, so that the optimal values
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40

Feder, Katya, and Robert Kerr. "Aspects of Motor Performance and Preacademic Learning." Canadian Journal of Occupational Therapy 63, no. 5 (1996): 293–303. http://dx.doi.org/10.1177/000841749606300505.

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This study examined preschool children's performance on a pursuit tracking task in relation to specific performance on motor and cognitive measures of preacademic skill development. Fifty children, ages 4.3 to 5.8 years were tested using the Miller Assessment for Preschoolers (MAP)and number/counting items. High and low performance groups were designated based on performance on the MAP, individual MAP spatial items as well as number/counting items. Groups were compared based on their performance on a pursuit tracking task. Results indicated that the low performance number/counting concept grou
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Hu, Chi Bing, Ya Zhou Wang, Shan Shan Chen, Jia Li Zhao, and Jun Gong. "On the Basis of Double Fuzzy Control of Honing Machine Reciprocating Motion." Applied Mechanics and Materials 226-228 (November 2012): 820–24. http://dx.doi.org/10.4028/www.scientific.net/amm.226-228.820.

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This paper mainly researches the control system of honing machine spindle reciprocating motion. On the basis of brief introduction to the processing of honing machines, its mathematic models were established, and design the double control system on the base of fuzzy control .Two fuzzy controllers were used separately according to actual error signal of the system output to improve the system rapidity and overshot .so that make the designed control system of honing machines spindle reciprocating motion can satisfy the design requirements better. Finally the control system was conducted by using
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42

Campbell, Kenneth S. "Filament Compliance Effects Can Explain Tension Overshoots during Force Development." Biophysical Journal 91, no. 11 (2006): 4102–9. http://dx.doi.org/10.1529/biophysj.106.087312.

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43

Cornille, Henri, and Yue-Hong Qian. "Temperature overshoots for a 4-velocity unidimensional discrete Boltzmann model." Journal of Statistical Physics 61, no. 3-4 (1990): 683–712. http://dx.doi.org/10.1007/bf01027297.

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44

PARK, Sehwan, Jihoon LIM, Wonil YANG, et al. "Turn-Off Electroluminescence Overshoots in Doped Alq Single-Layer Devices." New Physics: Sae Mulli 67, no. 3 (2017): 301–6. http://dx.doi.org/10.3938/npsm.67.301.

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45

Petrovskaya, N. B. "Two Types of Solution Overshoots in Discontinuous Galerkin Discretization Schemes." Communications in Mathematical Sciences 3, no. 2 (2005): 235–49. http://dx.doi.org/10.4310/cms.2005.v3.n2.a9.

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46

Klüppelberg, Claudia, Andreas E. Kyprianou, and Ross A. Maller. "Ruin probabilities and overshoots for general Lévy insurance risk processes." Annals of Applied Probability 14, no. 4 (2004): 1766–801. http://dx.doi.org/10.1214/105051604000000927.

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47

Spence, A., and Y. Altintas. "CAD Assisted Adaptive Control for Milling." Journal of Dynamic Systems, Measurement, and Control 113, no. 3 (1991): 444–50. http://dx.doi.org/10.1115/1.2896430.

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A milling process adaptive control method, which prevents force overshoots during sudden part geometry changes, has been developed by providing online information to the controller from the part’s CAD representation. A first-order discrete model structure to represent the milling process for adaptive control was analytically developed and experimentally identified. Provided with geometric information obtained from the part’s CAD model, and utilizing the milling force model, the adaptive controller predicts the maximum cutting force expected in advance of dangerous immersion changes. The techni
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48

Tamura, K., K. Ogata, and P. N. Nikiforuk. "Design of Nonovershoot MRACS With Application to D.C. Servo Motor System." Journal of Dynamic Systems, Measurement, and Control 113, no. 1 (1991): 75–81. http://dx.doi.org/10.1115/1.2896363.

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Excessive overshoots in a transient response are undesirable in a model reference adaptive control system (MRACS) and have to be avoided in practical applications. This paper discusses the design of an MRACS with no overshoot. In this design a d-step ahead estimator is introduced to evaluate the expected maximum and minimum values of the plant output. According to these estimates, the adaptive control input is adjusted so that the output has no overshoot. For the estimator and the input adjustment an existence region of the unknown plant parameters must be known. It is obvious that the smaller
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49

Meier, C. F., G. M. Briggs, and W. C. Claycomb. "Electrophysiological properties of cultured adult rat ventricular cardiac muscle cells." American Journal of Physiology-Heart and Circulatory Physiology 250, no. 5 (1986): H731—H735. http://dx.doi.org/10.1152/ajpheart.1986.250.5.h731.

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Action and resting potential characteristics of isolated adult rat myocardial cells maintained in culture for 10–28 days are described. Resting potentials averaged -76.3 +/- 2 mV in 5 mM extracellular [K+] ([K+]o). Resting potentials changed by 54.3 mV/decade change in [K+]o for concentrations greater than 5 mM. The average maximum rate of rise of action potential (Vmax) was 117.7 +/- 10 V/s with overshoots of 34.6 +/- 2.5 mV. Action potential durations (APD) to 0 and -40 mV and full repolarization were 21.8 +/- 3.9, 36.3 +/- 6.0, and 206 +/- 16.9 ms respectively. Action potential configuratio
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Nero, A. C., J. H. Schwartz, and M. R. Furtado. "Characteristics of H+ current transients induced by adverse H+ gradient pulses in toad bladder." American Journal of Physiology-Renal Physiology 253, no. 4 (1987): F606—F612. http://dx.doi.org/10.1152/ajprenal.1987.253.4.f606.

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Abstract:
Acidification in the toad bladder occurs as a result of electrogenic H+ secretion (JH). When a pH gradient is applied in a stepwise fashion in the absence of exogenous CO2, JH decreases linearly with the mucosal (M) solution pH and is null when pHm is approximately 4.5. When pHm is returned to initial values (7.4) in a stepwise fashion, JH increases linearly with pHm. However, on this return, higher values of JH are initially obtained. To investigate this hysteresis, hemibladders mounted in chambers were used to measure the change in the H+ current before and after acid pulses were applied to
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