Academic literature on the topic 'Oxazoles'

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Journal articles on the topic "Oxazoles"

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Murata, Yuki, Masato Kawakubo, Ayumi Maruyama, Mio Matsumura, and Shuji Yasuike. "Synthesis and Optical Properties of N-Arylnaphtho- and Anthra[2,3-d]oxazol-2-amines." Molecules 30, no. 2 (2025): 319. https://doi.org/10.3390/molecules30020319.

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Oxazole, a versatile and significant heteroarene, serves as a bridge between synthetic organic chemistry and applications in the medicinal, pharmaceutical, and industrial fields. Polycyclic aromatic compounds with amino groups substituted at the 2-position of an oxazole, such as 2-aminonaphthoxazoles, are expected to be functional probes, but their synthetic methods are extremely limited. Herein, we describe electrochemical reactions of 3-amino-2-naphthol or 3-amino-2-anthracenol and isothiocyanates in DMSO, using a graphite electrode as an anode and a platinum electrode as a cathode in the pr
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Yoshimura, Akira, Akio Saito, Viktor V. Zhdankin, and Mekhman S. Yusubov. "Synthesis of Oxazoline and Oxazole Derivatives by Hypervalent-Iodine-Mediated Oxidative Cycloaddition Reactions." Synthesis 52, no. 16 (2020): 2299–310. http://dx.doi.org/10.1055/s-0040-1707122.

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Organohypervalent iodine reagents are widely used for the preparation of various oxazolines, oxazoles, isoxazolines, and isoxazoles. In the formation of these heterocyclic compounds, hypervalent iodine species can serve as the activating reagents for various substrates, as well as the heteroatom donor reagents. In recent research, both chemical and electrochemical approaches toward generation of hypervalent iodine species have been utilized. The in situ generated active species can react with appropriate substrates to give the corresponding heterocyclic products. In this short review, we summa
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Yamada, Kohei, Naoto Kamimura, and Munetaka Kunishima. "Development of a method for the synthesis of 2,4,5-trisubstituted oxazoles composed of carboxylic acid, amino acid, and boronic acid." Beilstein Journal of Organic Chemistry 13 (July 27, 2017): 1478–85. http://dx.doi.org/10.3762/bjoc.13.146.

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A novel method for the synthesis of trisubstituted oxazoles via a one-pot oxazole synthesis/Suzuki–Miyaura coupling sequence has been developed. One-pot formation of 5-(triazinyloxy)oxazoles using carboxylic acids, amino acids and a dehydrative condensing reagent, DMT-MM, followed by Ni-catalyzed Suzuki–Miyaura coupling with boronic acids provided the corresponding 2,4,5-trisubstituted oxazoles in good yields.
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Ochędzan-Siodłak, Wioletta, Dawid Siodłak, Karolina Banaś, Katarzyna Halikowska, Sławomir Wierzba, and Karel Doležal. "Naturally Occurring Oxazole Structural Units as Ligands of Vanadium Catalysts for Ethylene-Norbornene (Co)polymerization." Catalysts 11, no. 8 (2021): 923. http://dx.doi.org/10.3390/catal11080923.

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1,3-Oxazole and 4,5-dihydro-1,3-oxazole are common structural motifs in naturally occurring peptides. A series of vanadium complexes were synthesized using VCl3(THF)3 and methyl substituted (4,5-dihydro-1,3-oxazol-2-yl)-1,3-oxazoles as ligands and analyzed using NMR and MS methods. The complexes were found to be active catalysts both in ethylene polymerization and ethylene-norbornene copolymerization. The position of methyl substituent in the ligand has considerable impact on the performance of (co)polymerization reaction, as well as on the microstructure, and thus physical properties of the o
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Chiacchio, Maria A., Giuseppe Lanza, Ugo Chiacchio, et al. "Oxazole-Based Compounds As Anticancer Agents." Current Medicinal Chemistry 26, no. 41 (2020): 7337–71. http://dx.doi.org/10.2174/0929867326666181203130402.

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: Heterocyclic compounds represent a significant target for anti-cancer research and drug discovery, due to their structural and chemical diversity. Oxazoles, with oxygen and nitrogen atoms present in the core structure, enable various types of interactions with different enzymes and receptors, favoring the discovery of new drugs. Aim of this review is to describe the most recent reports on the use of oxazole-based compounds in anticancer research, with reference to the newly discovered iso/oxazole-based drugs, to their synthesis and to the evaluation of the most biologically active derivative
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Regalla, Venkata Reddy, Rama Krishnam Raju Addada, Venkat Swamy Puli, Abhishek S. Saxena, and Anindita Chatterjee. "HIGHLY EFFICIENT SYNTHESIS OF 2,4-DISUBSTITUTED OXAZOLES THROUGH PALLADIUM/COPPER COMEDIATED DIRECT ARYLATION REACTION." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 511. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.26125.

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Objective: The aim of the present study is to synthesize 2,4-disubstituted oxazoles through palladium/copper comediated direct arylation reaction.Methods: 2,4-disubstituted oxazoles (3a-i) have been synthesized by the reaction of 4-substituted oxazole with aryl bromide in the presence of KOH , CuI and Pd(PPh3)4 in dimethoxyethane. Titled compounds (3a-i) were obtained in good yields using an expedient two-step synthesis of 2,4-disubstituted oxazoles from commercially available starting materialsResults: The structures of the newly synthesized compounds were characterized by Fourier-transform i
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Zanakhov, Timur O., Ekaterina E. Galenko, Mariya A. Kryukova, Mikhail S. Novikov, and Alexander A. Khlebnikov. "Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles." Molecules 26, no. 7 (2021): 1881. http://dx.doi.org/10.3390/molecules26071881.

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An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles. The latter were prepared by Rh2(oct)4 catalyzed reaction of 2-(3-aryl/heteroaryl)-2-diazoacetyl-2H-azirines with a set of substituted acetonitriles, benzonitriles, acrylonitrile and fumaronitrile. According to DFT calculations the transformation of 5-(2H-azirin-2-yl)oxazole to 4H-pyrrolo[2,3-d]oxazole occurs through the nitrenoid-like transition state to give a 3aH-pyrrolo[2,3-d]oxazole intermediate, followed by 1,5-
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He, Yuan, Ting Zheng, Yin-Hui Huang, and Lin Dong. "Rh(iii)-Catalyzed olefination to build diverse oxazole derivatives from functional alkynes." Organic & Biomolecular Chemistry 19, no. 22 (2021): 4937–42. http://dx.doi.org/10.1039/d1ob00507c.

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Clark, Adrian D., Uyen T. Ha, Rolf H. Prager, and Jason A. Smith. "High-Temperature Rearrangements of 2-Acylisoxazol-5(2H)-ones and Related Oxazoles." Australian Journal of Chemistry 52, no. 11 (1999): 1029. http://dx.doi.org/10.1071/ch99075.

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2-Acyl-3-arylisoxazol-5(2H)-ones give 2-alkyl(aryl)-4-aryloxazoles in good yields at 540°C under flash vacuum pyrolysis conditions, but at higher temperatures the expected oxazoles are accompanied by increasing amounts of isomeric 2,5-disubstituted oxazoles, as well as anilides and decomposition products of the 2,4-disubstituted oxazole. The rearrangement mechanisms have been studied by the use of 13C labelled substrates and p-substituted 3-arylisoxazolones. The 2,5-disubstituted oxazoles are considered to arise from 1H-azirines, and the anilides from the nitrone ketene isomer of the acylisoxa
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Šagud, Ivana, Simona Božić, Željko Marinić, and Marija Šindler-Kulyk. "Photochemical approach to functionalized benzobicyclo[3.2.1]octene structures via fused oxazoline derivatives from 4- and 5-(o-vinylstyryl)oxazoles." Beilstein Journal of Organic Chemistry 10 (September 18, 2014): 2222–29. http://dx.doi.org/10.3762/bjoc.10.230.

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Novel cis/trans-4- and cis/trans-5-(2-vinylstyryl)oxazoles have been synthesized by Wittig reactions from the diphosphonium salt of α,α’-o-xylene dibromide, formaldehyde and 4- and 5-oxazolecarbaldehydes, respectively. In contrast, trans-5-(2-vinylstyryl)oxazole has been synthesized by the van Leusen reaction from trans-3-(2-vinylphenyl)acrylaldehyde which is prepared from o-vinylbenzaldehyde and (formylmethylene)triphenylphosphorane. The 4- and 5-(2-vinylstyryl)oxazoles afford, by photochemical intramolecular cycloaddition, diverse fused oxazoline-benzobicyclo[3.2.1]octadienes, which are iden
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Dissertations / Theses on the topic "Oxazoles"

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Wills, Andrew Jonathan. "Studies on oxazolidines, oxazolines and oxazoles." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616146.

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Flegeau, Emmanuel Ferrer. "Palladium cross-couplings of oxazoles." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/3171.

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A review covering the literature until April 2008 concerning organometallic reactions to funcionalise oxazoles is described. A protocol for the functionalisation of the oxazole 2- and 4-positions using the Suzuki coupling reaction is described. 2- Aryl-4-trifloyloxazoles undergo rapid, microwave-assisted coupling with a range of aryl and heteroaryl boronic acids in good to excellent yields. The methodology is similarly effective using 4-aryl-2-chlorooxazoles as the coupling partner and has been extended to the synthesis of a novel class of homo- and heterodimeric 4,4- linked dioxazoles. In add
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Doyle, Kevin James. "Rhodium carbenoid route to oxazoles." Thesis, Loughborough University, 1994. https://dspace.lboro.ac.uk/2134/33073.

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This thesis describes investigations by the author into the preparation of the oxazole heterocyclic system, by the use of rhodium carbenoid methodology. Chapter 1 is a review of the literature on the formation of oxazoles, by the reaction between diazocarbonyl compounds and nitrites. The various conditions that have been employed in the reaction are detailed, as well as developments into the understanding of its mechanism. Chapter 2 reports the study into the preparation of 4-functionalised oxazoles. A series of 4- benzenesulfonyloxazoles, oxazole-4-phosphates and oxazole-4-carbonitriles were
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Gillie, Andrew Duncan. "Synthesis and applications of 4N-substituted oxazoles." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/6374/.

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This thesis describes the advancement of a flexible and convergent gold-catalysed synthesis of trisubstituted oxazoles, and its application to the synthesis of novel polycyclic compounds. Following on from the initial discovery of this reaction, its scope and limitations have been have been explored, leading to a significant increase in the range of functionality which can be incorporated into the products. This reaction, and the novel structure of the 4-amido oxazole products, was then exploited to allow the construction of other complex molecules. A one-pot reaction cascade has been develope
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Adetchessi, Ouro-Sama. "Conception et synthèse de 2-Amino-2-Oxazolines : contribution à l'étude de leur réactivité." Bordeaux 2, 1996. http://www.theses.fr/1996BOR2B003.

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Kozlik, Roza Maria. "The chemistry of palladacycles derived from phenyl-oxazolines /." abstract and full text PDF (UNR users only), 2007. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3279641.

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Thesis (Ph. D.)--University of Nevada, Reno, 2007.<br>"May, 2007." Includes bibliographical references. Library also has microfilm. Ann Arbor, Mich. : ProQuest Information and Learning Company, [2008]. 1 microfilm reel ; 35 mm. Online version available on the World Wide Web.
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Pertler, Stephanie L. "Synthesis of 3-arylisoxazoles and 5-arylisoxazoles." Virtual Press, 2006. http://liblink.bsu.edu/uhtbin/catkey/1348869.

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The goal of this research project was to synthesize a small library of 3- and 5-arylisoxazoles. These compounds are of interest because of potential biological activity similar to Fipronil. Fipronil is used commercially in the agrochemical industry and exhibits pesticidal activity as a noncompetitive inhibitor of the GABA receptor. By deleting the amino group normally at the 5-position and the cyano group normally at the 3-position and changing the atoms in the heterocyclic ring from containing two nitrogen atoms to one nitrogen and one oxygen atom, we hope to create changes in the binding so
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Muir, James C. "The total synthesis of curacin A and muscoride A." Thesis, University of Nottingham, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285632.

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Gaulon-Nourry, Catherine. "Les N-vinyl-2-oxazolidinones, nouveaux diénophiles en hétérocycloaddition [4+2] : application à la synthèse asymétrique de N-glucosides originaux." Le Mans, 2003. http://cyberdoc.univ-lemans.fr/theses/2003/2003LEMA1010.pdf.

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Notre travail a consisté à étudier la réactivité inédite des N-vinyl-2-oxazolidinones en tant que diénophiles en hétérocycloaddition [4+2] à demande inverse. Après avoir mis au point une méthode simple et efficace pour synthétiser les N-vinyl-2-oxazolidinones, leur réactivité a été étudiée vis-à-vis de divers hétérodiènes activés de type a-cétoester ß,?-insaturé. En présence d'une quantité catalytique d'Eu(fod)3 et au reflux du cyclohexane, les cycloadditions ont conduit à des dihydropyranes fonctionnalisés originaux avec un rendement élevé, une endo-sélectivité quasiment totale et une diastér
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Perry, Martin Harold. "The synthesis of novel nitrogen heterocycles in the field of phthalocyanines and oxazoles." Thesis, Keele University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320249.

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Books on the topic "Oxazoles"

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J, Turchi I., ed. Oxazoles. Wiley, 1986.

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Palmer, David C., ed. Oxazoles: Synthesis, Reactions, and Spectroscopy. John Wiley & Sons, Inc., 2004. http://dx.doi.org/10.1002/0471649295.

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C, Palmer David, ed. Oxazoles: Synthesis, reactions, and spectroscopy. Wiley, 2003.

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Palmer, David C., ed. Oxazoles: Synthesis, Reactions, and Spectroscopy, Part A. John Wiley & Sons, Inc., 2003. http://dx.doi.org/10.1002/0471428035.

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Lapkin, I. I. Slozhnye ėfiry [alʹfa]-okso- i [alʹfa]-oksikislot. UrO AN SSSR, 1990.

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Grünanger, Paolo. Isoxazoles. Wiley, 1991.

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Schwarzenbach, Elmar. Kationische ringöffnende Polymerisation von bicyclischen Acetalen und von 2-Phenyl-2-Oxazolin [Phenyl-Oxazolin]. [s.n.], 1987.

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Muzanila, Charles Nobert. Heterocyclic transformations involving 2 oxazolines and 1.2-benzisoxazoles. University of Salford, 1989.

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Trethewey, Andrew Nicholas. Synthesis and evaluation of perhydro-oxazolo [3,4-a] pyridines as fungicides. Portsmouth Polytechnic, 1985.

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Hohn, Ida Marcia. Kinetic studies of the metathesis of 1-hexene using Re2O7/y-Al2O3 and the synthesis and metathesis of oxazolines. Aston University. Department of Chemical Engineering and Applied Chemistry., 1991.

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Book chapters on the topic "Oxazoles"

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Rauf, Abdul, and Nida Nayyar Farshori. "Oxazoles." In SpringerBriefs in Molecular Science. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-1485-4_2.

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Turchi, Ignatius J. "Oxazoles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187289.ch1.

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Maryanoff, Bruce E. "Oxazoles and Oxazolines in Organic Synthesis." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187289.ch5.

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Gingrich, Henry L., and Jonathan S. Baum. "Mesoionic Oxazoles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187289.ch4.

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Maryanoff, Cynthia A. "Spectroscopic Properties of Oxazoles." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187289.ch2.

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Li, Jie Jack. "Hodges-Vedejs metallation of oxazoles." In Name Reactions. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05336-2_143.

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Fu, Liangfeng. "Metalation of Oxazoles and Benzoxazoles." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_81.

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Yurovskaya, M. A. "Fluorinated Oxazoles, Thiazoles and Selenazoles." In Fluorine in Heterocyclic Chemistry Volume 1. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04346-3_10.

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Li, Jie Jack. "Hodges—Vedejs metallation of oxazoles." In Name Reactions. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_133.

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Kunieda, Takehisa, and Hirofumi Matsunaga. "2(3H )-Oxazolones and 2(5H )-Oxazolones." In Oxazoles: Synthesis, Reactions, and Spectroscopy. John Wiley & Sons, Inc., 2004. http://dx.doi.org/10.1002/0471649295.ch5.

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Conference papers on the topic "Oxazoles"

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Abegão, Luis M. G., Ruben D. Fonseca, Francisco A. Santos, et al. "First Molecular Electronic Hyperpolarizability of Two Oxazoles Dyes in Solution." In Latin America Optics and Photonics Conference. OSA, 2018. http://dx.doi.org/10.1364/laop.2018.th4a.10.

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Sreenivasulu, T., G. Mallikarjuna Reddy, G. Sravya, A. Padmaja, and Grigory V. Zyryanov. "Synthesis, characterization and antimicrobial activity of pyridine linked hydrazinyl oxazoles/imidazoles." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087387.

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Sravya, G., N. Bakthavatchala Reddy, and Grigory V. Zyryanov. "Synthesis, structural elucidation and bioassay of morpholine/thiomorpholine and piperidine containing oxazoles." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018089.

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Gonçalves, M. Sameiro, Susana Costa, and Ana Soares. "Novel fused oxobenzopyrano[6,7-d]oxazoles as light-triggered protecting groups for carboxylic acids." In The 14th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00440.

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Shablykin, O., O. Kobzar, Ya Prostota, et al. "Topological Index of Electronic Structure of Conjugated Substituted Bis-Oxazoles and Their Spectral-Luminescent Properties." In 2018 IEEE 38th International Conference on Electronics and Nanotechnology (ELNANO). IEEE, 2018. http://dx.doi.org/10.1109/elnano.2018.8477468.

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Semenyuta, Ivan. "5-AMINO-4-CYANO-1,3-OXAZOLES AS NEW ANTIBACTERIALS AGAINST ANTIBIOTIC-RESISTANT ESCHERICHIA COLI STRAINS." In SCIENTIFIC PRACTICE: MODERN AND CLASSICAL RESEARCH METHODS, chair Diana Hodyna, Vasily Kovalishin, Bohdan Demydchuk, Stepan Pilyo, and Larysa Metelytsia. European Scientific Platform, 2023. http://dx.doi.org/10.36074/logos-26.05.2023.030.

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Spanò, Virginia, Daniele Giallombardo, Alessandra Montalbano, et al. "Abstract C097: Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles: A new class of antimitotic agents." In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c097.

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González-Zamora, Eduardo, Rocío Gámez-Montaño, Alejandro Islas-Jácome, et al. "Ultrasound-assisted synthesis of eight novel and highly functionalized 2-aminonitrile oxazoles via Ugi-3CR." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04818.

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Kobayashi, Kaori, and Shozo Tsunekawa. "MICROWAVE SPECTROSCOPY OF OXAZOLE AND ISOXAZOLE." In 74th International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2019. http://dx.doi.org/10.15278/isms.2019.ti07.

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Princival, Cleverson R., Alfredo R. M. de Oliveira, João V. Comasseto, and Jefferson L. Princival. "Enzimatyc Kinetic Resolution of Hydroxy Oxazolines." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0339-1.

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