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Dissertations / Theses on the topic 'Oxidation des lipides'

Author: Grafiati

Published: 8 June 2024

Last updated: 31 July 2025

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1

Garcia, Darras Carolina. "Conception et développement d'un microcalorimètre pour l'étude de l'oxydation d'une huile végétale." Thesis, Bordeaux 1, 2012. http://www.theses.fr/2012BOR14517/document.

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L’oxydation des lipides est un phénomène complexe qui génère de nombreux produits qu’il est nécessaire de caractériser de manière précise afin de prévenir leur apparition. Parmi les méthodes pour analyser les produits d’oxydation, l’analyse thermique différentielle, basée sur la mesure différentielle du flux de chaleur dissipé au cours des réactions d’oxydation, est intéressante car elle n’utilise pas de solvant organique. De plus, elle peut être corrélée à l’apparition de produits primaires ou secondaires d’oxydation. Dans ce contexte, nous avons conçu et développé un microcalorimètre basé su

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2

Al-Sayed, Mahmoud Kassem. "Extraction, fractionnement et caractérisation des lipides polyinsaturés d'oeufs de la truite arc-en-ciel (Oncorhynchus mykiss)." Thesis, Vandoeuvre-les-Nancy, INPL, 2007. http://www.theses.fr/2007INPL087N/document.

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Parmi les œufs de poisson, qui sont une ressource aquatique nutritionnelle intéressante, ceux de la truite arc-en-ciel (Oncorhynchus mykiss) contiennent une quantité élevée de protéines et une huile riche en acides gras polyinsaturés (AGPI), avec une proportion très importante de phospholipides. Cependant, l’œuf de poisson présente une capacité élevée d’auto-protection contre les contraintes extérieures, qui limite la destructuration de son réseau protéique par attaque enzymatique. Ainsi, le degré d’hydrolyse des œufs de la truite l’Alcalase®, la Neutrase® et la Protamex® varie entre 3 et 7 %,

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3

Pernin, Aurélia. "Action antioxydante et antimicrobienne de composés phénoliques dans des milieux modèles et des émulsions riches en lipides insaturés." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLA033/document.

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Les composés phénoliques pourraient être de bons candidats pour assurer la qualité et la sécurité des produits périssables tels que les aliments prêts-à-consommer. Très répandus dans les plantes et les co-produits agro-industriels, ils peuvent limiter l’oxydation de lipides insaturés d’intérêt nutritionnel (omega-3, dont DHA et EPA) et le développement de bactéries pathogènes alimentaires telles que Listeria monocytogenes.L'objectif de cette thèse est d'évaluer la double activité antioxydante et antimicrobienne de ces composés phénoliques dans des milieux alimentaires complexes et de mieux com

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4

Socrier, Larissa. "Influence de la localisation d’antioxydants sur la peroxydation des lipides membranaires : étude du mode d’action de dérivés PBN et de composés phénoliques." Thesis, Compiègne, 2017. http://www.theses.fr/2017COMP2382/document.

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Les espèces réactives de l’oxygène (EROs) sont essentielles à la survie des cellules car elles interviennent dans divers processus physiologiques comme la défense immunitaire ou encore la régulation de voies de signalisation cellulaires. Cependant, un excès d’EROs peut créer un déséquilibre de la balance EROs/antioxydants appelé « stress oxydant ». Le stress oxydant étant impliqué dans l’étiologie de plus de 200 pathologies, l’action des antioxydants est cruciale pour limiter les effets délétères des EROs. Les antioxydants utilisés par les cellules peuvent être de nature chimique. Parmi ceux-c

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5

Roman, Olesea. "Mesure et prédiction de la réactivité des lipides au cours du chauffage d'huiles végétales à haute température." Phd thesis, AgroParisTech, 2012. http://pastel.archives-ouvertes.fr/pastel-00806186.

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Si les lipides contribuent à la valeur nutritionnelle et sensorielle de nombreux aliments, ils sont particulièrement sensibles aux réactions d'oxydation. Les principaux mécanismes mis en jeu lors de l'oxydation des acides gras insaturés sont relativement bien connus. En revanche, il est aujourd'hui quasiment impossible de prédire l'avancement des réactions et souvent nécessaire de recommencer une nouvelle étude de stabilité oxydative pour tout nouveau couple produit alimentaire / procédé de transformation. L'objectif de la thèse est donc de construire un modèle mécanistique couplé à un modèle

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6

Du, Zhen-Yu. "Consequences of fat feeding on growth and body lipids in a herbivorous fish (Grass carp, Ctenopharyngodon idella) : mechanisms related to fatty acid oxidation." Dijon, 2005. http://www.theses.fr/2005DIJOS019.

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L'objectif de cette thèse est d'évaluer si des régimes riches en graisse peuvent être donnés en élevage aux poissons herbivores. La carpe d'herbe prise comme modèle présente des capacités limitées à utiliser les lipides, avec, sur le long terme, de l'anorexie, une croissance diminuée et une accumulation de lipides dans plusieurs organes. Les capacités du foie à oxyder les acides gras, via les mitochondries et peroxysomes, sont faibles et associées à une accumulation d'acides gras polyinsaturés (PUFA) dans les liquides corporels. L'ingestion en excès d'huile de poisson aboutit à une peroxydatio

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7

Ayoub, Pierre. "Molecular dynamics study of pyrene excimer formation and oxidation in lipid bilayer models." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAE038/document.

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Nous proposons une nouvelle approche pour déterminer le coefficient de diffusion dans des membranes lipidiques se basant sur la formation d'excimères. Alors que les autres modèles statistiques considèrent le système comme un ensemble de points sur un réseau, nous utilisons un modèle à gros grain afin d'étudier des bicouches lipidiques simulées à l'aide du champs de force Martini. Nous déterminons le taux de réaction dépendant du temps à partir des probabilités de survie obtenues a posteriori à l'aide des trajectoires numeriques des bicouches symétriques de DOPC (1,2-Dioleoyl-sn-glycero-3-phosp

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8

Garcia, Mendoza Maria del Pilar. "Enrichissement d’huiles végétales par des antioxydants de type phenolique en vue d’applications alimentaires." Thesis, Bordeaux, 2020. http://www.theses.fr/2020BORD0196.

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Les huiles végétales comme les huiles de cameline et tournesol sont des sources d’acides gras polyinsaturés bon pour la santé mais également très sensibles à la dégradation oxydative. Ce travail vise à améliorer la stabilité oxydative d’huiles alimentaires (principalement l’huile de cameline) via l’incorporation de composés phénoliques antioxydants soit comme composé pur (quercétine) soit comme un mélange plus complexe extrait à partir d’un coproduit de la noix. La faible solubilité de la quercétine dans l’huile a été contournée avec succès par le développement d’une voie d’enrichissement sans

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9

Masoud, Rawand. "Modulating the activity of NADPH oxidase by oxidative stress participants ; lipids and nanoparticles A cell-free system study." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS028/document.

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La NADPH oxydase de phagocyte est un complexe enzymatique impliqué dans la défense immunitaire contre les pathogènes. Elle est constituée du flavocytochrome b558 membranaire (Cyt b558), composé de deux sous-unités (gp91phox et p22phox) et de quatre sous-unités cytosolubles, p47phox, p67phox, p40phox, et Rac. Sa fonction est de produire au niveau de la paroi des pathogènes des ions superoxyde (O2•−) qui sont transformés en d'autres espèces réactives de l'oxygène (ROS) qui attaquent les lipides, les protéines et l’ADN environnants. Après activation du phagocyte, les sous-unités cytosoliques subi

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10

Kaleem, Muhammad. "Effets des produits d'oxydation de l'acide linoléique sur sa biohydrogénation ruminale." Thesis, Toulouse, INPT, 2013. http://www.theses.fr/2013INPT0042/document.

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La biohydrogénation (BH) ruminale des acides gras polyinsaturés (AGPI) est à l’origine de la production d’AG trans pouvant se retrouver dans les productions de ruminants, dont le lait. Parmi ceux-ci, les isomères t11 auraient des effets bénéfiques pour la santé des consommateurs alors que les isomères t10 sont potentiellement défavorables. En élevage, l’apport de graines oléagineuses dans la ration des vaches permet d’augmenter la teneur du lait en ces acides gras. Or ces graines sont souvent distribuées chauffées pour améliorer leur valeur nutritionnelle. Expérimentalement, les effets des gra

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11

MEBARKI, SLIMANE. "Contribution a l'etude de l'utilisation metabolique de divers acides gras par l'adipocyte de rat : effets de l'age et des lipides alimentaires." Paris 7, 1987. http://www.theses.fr/1987PA077225.

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12

Guzun-Cojocaru, Tatiana. "Peroxydation des lipides émulsionnés et transfert d'ions fer à l'interface huile / eau stabilisée par des protéines de lait : influence des résidus phosphates et de la stabilité du chélate de fer." Thesis, Dijon, 2010. http://www.theses.fr/2010DIJOS012/document.

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Le fer ajouté dans des systèmes complexes tels que les aliments induit divers problèmes comme l'oxydation des lipides ou la précipitation d’autres composés présents dans la matrice. Il s’en suit une diminution de sa biodisponibilité et des défauts de goût. L'utilisation de chélates de fer, comme le bisglycinate de fer ou l’EDTA de fer, constitue une voie intéressante : le fer ainsi protégé n’interagirait pas avec la matrice alimentaire. La stabilité des chélates de fer (bisglycinate de fer et NaFe EDTA), supposés peu réactif pour l’initiation de peroxydation, a été attestée sur des modèles d’é

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13

Musigamart, Natedao. "Study of the role of lipids from maturated coagula from Hevea brasiliensis latex on natural rubber behavior in oxidative conditions." Thesis, Montpellier, SupAgro, 2015. http://www.theses.fr/2015NSAM0004/document.

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Le caoutchouc naturel (CN), un produit dérivé du latex d'Hevea brasiliensis, est connu pour ses propriétés mécaniques supérieures pour certaines à celles de ses concurrents synthétiques. Néanmoins, le haut degré d'insaturation du poly(cis-1,4-isoprene) le rend susceptible à la thermo-oxydation. Heureusement, le CN est doté de composés non-isoprènes dont certains ont des propriétés antioxydantes. Les lipides sont les plus importants non-isoprènes retenus dans le caoutchouc et contiennent des molécules à activité antioxydante en particulier les tocotriènols. Il est connu que durant la maturation

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14

Škrabalová, Lada. "Hemoglobin-mediated oxidation of marine liposomes." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2012. http://www.nusl.cz/ntk/nusl-216833.

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Cílem této práce bylo studium mechanismu oxidace lipidů katalyzované hovězím methemoglobinem a zhodnocení účinků různých experimentálních podmínek a antioxidantů (EDTA, askorbová kyselina, kávová kyselina, a-tokoferol, d-tokoferol, astaxanthin a L-askorbyl-6-palmitát) na methemoglobinem zprostředkovanou oxidaci lipidů v modelovém systému liposomů připravených z fosfolipidů. K monitorování oxidace lipidů při pH 5,5 a teplotě 30 °C bylo použito spotřeby kyslíku. Pro zhodnocení antioxidační aktivity v modelovém systému liposomů se ukázaly být důležitými faktory typ prooxidantu a koncentrace proox

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15

Janani, Tahereh. "Herbs as antioxidants in oxidation of marine lipids." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for biologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-23597.

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Marine lipids have beneficial health effects due to the high content of long chain polyunsaturated omega-3-fatty acids (LC-PUFA), especially EPA (eicosapentanoic acid) and DHA (docosahexanoic acid) and they aretherefore of interest to use in products for human consumption.Marine phospholipids are very susceptible to lipid oxidation, due to the high amount of n-3 PUFAs, which cause loss of sensory and nutritional value in foods.In order to prevent the oxidation reactions, it is important to find out more on how different factors and compounds, such as pro- and antioxidants in the food, affect t

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16

Sparks, Darrell Lynn. "Oxidation of lipids in a supercritical-fluid medium." Diss., Mississippi State : Mississippi State University, 2008. http://library.msstate.edu/etd/show.asp?etd=etd-03252008-162949.

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17

Reid, Vanessa Claire. "Macrophage toxicity of lipid oxidation." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308384.

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18

Nogueira, Marina Sayuri. "Avaliação do consumo de lipídios oxidados na indução do estresse oxidativo associado à aterosclerose em modelo animal." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-22122015-091244/.

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Estudos envolvendo cultura de células, animais e humanos tem sido extensivamente aplicados no monitoramento da aterosclerose, visando seu controle ou mesmo reversão. Entre os modelos animais atualmente utilizados, tem-se observado uma resposta adequada à indução de dislipidemia e inflamação, porém elevada resistência à indução de estresse oxidativo. Uma alternativa para superar essa limitação seria a ingestão de dietas contendo ácidos graxos oxidados. Entretanto, os estudos que investigaram o efeito do consumo de peróxidos e produtos secundários da oxidação lipídica na progressão da ateroscler

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19

Ma, Yanshan. "Factors Influencing the Oxidation of Lipoproteins and Plasma Lipids." Digital Commons @ East Tennessee State University, 1994. https://dc.etsu.edu/etd/2724.

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The hypothesis that antioxidant vitamins (ascorbate and tocopherols) along with urate protect blood plasma lipids from oxidation was tested. Dietary fat is also an important factor influencing plasma lipid peroxidation. The purpose of this study was to investigate the role of plasma antioxidants and dietary fat on low density lipoprotein (LDL) and plasma lipid oxidation. In the first part of this study, we compared the ability of urate and ascorbate to protect human LDL from in vitro oxidation. LDL oxidation was initiated by 15 mM of a water soluble azo-initiator in the presenc

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20

Anderson, Richard Anthony. "Lipids, oxidative stress and endothelial function." Thesis, King's College London (University of London), 2004. https://kclpure.kcl.ac.uk/portal/en/theses/lipids-oxidative-stress-and-endothelial-function(ca261d48-d716-4156-9a38-dbb72775b36a).html.

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21

Fogaça, Fabíola Helena dos Santos [UNESP]. "Efeito do tocoferol no desempenho e na estabilidade lipidica da tilápia nilotica (Oreochromis niloticus)." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/86711.

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Made available in DSpace on 2014-06-11T19:22:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-01-27Bitstream added on 2014-06-13T19:48:40Z : No. of bitstreams: 1 fogaca_fhs_me_jabo.pdf: 596326 bytes, checksum: 558f30e4e45f55982f56059d2fab70b4 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Universidade Estadual Paulista (UNESP)<br>A vitamina E é usada nas dietas com a finalidade de melhorar o crescimento, a resistência ao estresse e a doenças, assim como a sobrevivência de peixes. Também pode ser eficiente na conservação do pescado durante o processam

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22

Ng, Su Chuen. "Effects of accelerated aging on lipid oxidation in quinoa (Chenopodium quinoa)." Online version, 2003. http://www.uwstout.edu/lib/thesis/2003/2003ngs.pdf.

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23

Telles, Scott Gerard. "Change in zinc permeability of lipid bilayers as a function of fluidity and oxidation." Virtual Press, 1997. http://liblink.bsu.edu/uhtbin/catkey/1061869.

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The main goal in my project was find out if the rate of zinc crossing the bilayer was either due to the fluidity of vesicles or the level of oxidation of the vesicles.To measure the oxidation a simple procedure called the TBA Test was used to measure each PC tested. The fluidity measurement was a calculation using the temperature the vesicles went from gel to liquid crystalline phase and the experimental temperature.Measuring the rate at which zinc crossed the bilayer was done using spectral changes that occur as zinc binds with APIII, a metal chelator entrapped inside the vesicles. To measure

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24

Chido, Chakanya. "Fatty acid composition, colour stability and lipid oxidation of mince produced from fresh and frozen/thawed fallow deer meat." Thesis, University of Fort Hare, 2016. http://hdl.handle.net/10353/2479.

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The aim of the study was to determine the fatty acid composition, colour stability and lipid oxidation of fresh mince produced from fallow deer and to evaluate the effect of frozen storage duration on the retail display shelf life of the mince. A total of 31 fallow deer carcasses were used in the study. After cooling for 24hrs, the carcasses were deboned, external fat from the fore and hindquarter muscles removed and individually vacuum packed. For the first trial, seven fallow deer carcasses were used. Meat from the hind and fore-quarters of each carcass was divided into two equal batches per

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25

Mahachi, Leo Nyikadzino. "Physiochemical, fatty acids, lipid oxidation, sensory characteristics and consumer acceptance of warthog cabanossi produced with pork backfat and fat-tailed sheep backfat." Thesis, University of Fort Hare, 2017. http://hdl.handle.net/10353/6259.

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The objective of this study was to determine the effect of different fat inclusion levels and fat types on the physical and chemical attributes, lipid oxidation, fatty acid composition and sensory characteristics of warthog cabanossi. To achieve this, three types of cabanossi with different pork backfat levels (10 percent, 20 percent and 30 percent) were produced for the first experiment. The results from the study showed that different inclusion levels of pork backfat had an influence (P ≤ 0.05) on the physicochemical and fatty acid composition of warthog cabanossi but did not influence lipid

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26

Prado-Barragan, Lilia Arely. "Lipid oxidation in a meat fibre system." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294811.

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27

Walters, Louise. "Lipid oxidation in salt-dried pelagic fish." Thesis, University of Lincoln, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262195.

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28

McMoneagle, Andrew. "Antioxidant behaviour in photo-oxidation studies of model lipid compounds." Thesis, University of the West of Scotland, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311777.

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29

Pradhan, Arati S. "Diffusion of zinc through oxidized lipid bilayers." Virtual Press, 2000. http://liblink.bsu.edu/uhtbin/catkey/1166400.

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Egg phosphatidylcholine was oxidized by atmospheric oxygen under UV light for 16 hours, and the oxidized products formed were fractionated with high-pressure liquid chromatography in reverse phase. Three fractions that appeared at retention times of 19 minutes, 21 minutes and 24 minutes respectively (fraction 19, fraction 21 and fraction 24) were isolated and stabilized by reduction with triphenylphosphine. Zinc diffusion across 1-palmitoyl-2 oleoyl-sn-glycero-3-phosphocholine (POPC) liposome bilayers mixed with the isolated oxidized fractions was measured. The rate constant for zinc diffusion

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30

Noble, Ronald. "Sensory methods used in meat lipid oxidation studies." Kansas State University, 2018. http://hdl.handle.net/2097/38563.

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Master of Science<br>Food Science Institute<br>Kadri Koppel<br>Oxidation of meat decreases consumer acceptance and reduces market value making it an important problem for the meat industry. Odor and flavor of meat are significantly affected by lipid oxidation and researchers continue to explore new ways to control meat oxidation. Natural antioxidants, irradiation and oxygen treatments are major areas of research in meat lipid oxidation. In recent studies researchers have been exploring ways to extend shelf life of meat and in many case rely on sensory results. This report deals with sensory m

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31

Hoyland, David Vernon. "Chemical methods for assessing lipid oxidation in food." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254588.

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Smith, G. "Lipid oxidation in S.E. Asian salted-dried fish." Thesis, University of Lincoln, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380661.

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Jenkins, Benjamin John. "The role of alpha oxidation in lipid metabolism." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/278025.

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Recent findings have shown an inverse association between the circulating levels of pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) with the risk of pathological development in type 2 diabetes, cardio vascular disease and neurological disorders. From previously published research, it has been said that both these odd chain fatty acids are biomarkers of their dietary intake and are significantly correlated to dietary ruminant fat intake. However, there are profound studies that show the contrary where they do not display this biomarker correlation. Additionally, several astute studies

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Vereb, Heather A. "Biomarkers of Lipid Oxidation in the Oral Cavity." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/76887.

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Measuring lipid oxidation is useful as a means of monitoring oxidative stress, such as that induced by clinical conditions or environmental exposure. Characteristic volatile compounds, often with low threshold odors, are secondary products of lipid oxidation reactions. Metallic flavor in food and beverages has been linked with oxidation of lipids in the oral cavity. Breath, an emerging medium for analysis of internal condition, is one means of measuring the metal-induced lipid oxidation responsible for this flavor. This project analyzes the breath of human subjects, as well as lipid oxidat

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Saeed, Suhur. "Lipid oxidation mechanisms and lipid-protein interactions in frozen mackerel (Scomber scombrus)." Thesis, University of Surrey, 1998. http://epubs.surrey.ac.uk/843251/.

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Atlantic mackerel (Scomber scombrus) is a pelagic fish widely distributed along the Northern coast of Great Britain. The lipid content of mackerel was found to be about 13% of the total body weight and 50% of total fatty acids were eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (fatty acids which are reported to reduce the concentration of plasma triglycerides, LDL (low density lipoproteins) and cholesterol in humans and animals). The proximate analysis also showed that mackerel is a good source of protein (20% w/w). The poly unsaturated fatty acids (PUFA) are prone to oxidation du

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de, Miguel Pastor Cristina. "Lípidos de la dieta y cáncer de mama experimental: efectos sobre el estrés oxidativo." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399983.

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El cáncer de mama es el más frecuente en mujeres de todo el mundo. Además de los factores genéticos, epigenéticos y hormonales, existen evidencias epidemiológicas y experimentales de que los factores nutricionales y ambientales tienen un papel en la etiología y el desarrollo de esta enfermedad. Los lípidos de la dieta se han relacionado directamente con el cáncer, fundamentalmente, el de mama. Resultados previos demostraron que las dietas hiperlipídicas de aceite de maíz, rico en ácidos grasos poliinsaturados (PUFA) n-6, y el aceite de oliva virgen extra, rico en ácidos grasos monoinsaturados

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Ingram, Katherine Heimburger. "Skeletal Muscle Lipid Peroxidation and its Relationships with Intramyocellular Lipids and Insulin Sensitivity in Obese Subjects." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/kin_health_diss/6.

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Intramyocellular lipid (IMCL), an ectopic fat depot found within skeletal muscle fibers, is highly associated with obesity and strongly correlated with insulin resistance. IMCL accumulation in sedentary individuals may contribute to insulin resistance by interfering with insulin signaling in skeletal muscle, leading to inadequate glucose uptake by the cell. Lipid peroxidation is also associated with both obesity and insulin resistance, and with IMCL, but a relationship has yet to be established among all of these variables. The purpose of this project is to study for the first time the relati

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Bôas, Eloísa Aparecida Vilas. "Tratamento crônico com ácido palmítico aumenta o conteúdo de superóxido e a apoptose de células BRIN-BD11com participação da NADPH oxidase, sem envolvimento do GPR40." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/42/42137/tde-18062014-132020/.

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A exposição crônica a ácidos graxos (AG) saturados leva à disfunção da célula beta pancreática com redução da secreção de insulina e apoptose, fenômeno conhecido como lipotoxicidade, que está relacionado a: estresse de retículo endoplasmático (RE), estimulação crônica do receptor de AG GPR40 e aumento de espécies reativas de oxigênio (ERO) provenientes, entre outras fontes, da enzima NADPH oxidase. Pretendeu-se explorar como mecanismos de lipotoxicidade: o estresse de RE, a estimulação crônica do GPR40 e a geração de ERO pela NADPH oxidase, bem como relações entre NADPH oxidase e estresse de R

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Oliveira, Patrícia Martinez. "Avaliação dos efeitos hipolipêmico e antioxidante in vivo dos extratos hidroalcoólicos da folha e raíz do yacon (smallanthus sonchifolius)." Universidade Federal do Pampa, 2015. http://dspace.unipampa.edu.br:8080/xmlui/handle/riu/261.

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Submitted by Marcos Anselmo (marcos.anselmo@unipampa.edu.br) on 2015-11-18T19:21:29Z No. of bitstreams: 1 Patricia Martinez.pdf: 1740129 bytes, checksum: 2e78fca15b7342e0463a1eb9c89b943a (MD5)<br>Made available in DSpace on 2015-11-18T19:21:30Z (GMT). No. of bitstreams: 1 Patricia Martinez.pdf: 1740129 bytes, checksum: 2e78fca15b7342e0463a1eb9c89b943a (MD5) Previous issue date: 2015-08-14<br>As doenças cardiovasculares (DCV) lideram as causas de morte em todo o mundo, sendo a dislipidemia o principal fator de risco. A alimentação é reconhecida como a intervenção mais importante na preven

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Kristinova, Vera. "Oxidation of marine lipids in liposomes and emulsions mediated by iron and methemoglobin." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for bioteknologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-25022.

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Long chain omega-3 polyunsaturated fatty acids (LC omega-3 PUFA) are vital for physiological functions and have therapeutic and health benefits. The consumption of LC PUFA in the Western world has been below recommended intake levels the past decades, despite promotion of seafood and omega-3 supplements. Incorporation of the LC PUFA into processed food consumed on a daily basis might therefore bridge the gap between the recommended and actual consumption of LC omega-3 PUFA. Unfortunately, the development of omega-3 enriched food is hampered by a very high susceptibility of LC PUFA to oxidative

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Filho, Adriano de Britto Chaves. "Eventos redox na biologia dos lipídios: modificação de tióis e alterações do lipidoma em ALS." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-20072018-085559/.

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Os lipídeos abrangem uma ampla gama de moléculas hidrofóbicas presentes nas células. As características moleculares dos lipídios determinam sua localização celular e função biológica. Em geral, os lipídios são considerados componentes essenciais de membranas, reservatórios de energia e moduladores de vias de sinalização ligadas ao metabolismo celular, sobrevivência, entre outros. Em mamíferos, grande parte dos lipídios é esterificada em ácidos graxos poli-insaturados (PUFAs), especialmente os ácidos docosahexaenóico (DHA) e araquidônico (ARA), essenciais para vários processos fisiológicos, inc

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Bothma, Karien. "The involvement of lipid and protein oxidation in hypertension : the SABPA study / Karien Bothma." Thesis, North-West University, 2012. http://hdl.handle.net/10394/8652.

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Oxidative stress, caused by increased levels of reactive oxygen species (ROS)and reactive nitrogen species (RNS) and/or a decrease in antioxidant capacity, can result in the oxidation of various bio-molecules, such as proteins, lipids and deoxyribonucleic acid (DNA). These oxidized bio-molecules may contribute to pathologies such as cardiovascular diseases, neurodegenerative disorders and cancer. The Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA) study was initiated in 2008 to investigate the coping styles and catecholamine metabolic markers of Africans, contributing to

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Turner, Rufus. "Lipid oxidation by denatured haemproteins in heat-processed vegetables." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365990.

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Arnold, Andrew Richard. "Lipid oxidation in a model system and in meat." Thesis, University of St Andrews, 1989. http://hdl.handle.net/10023/14168.

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Lipid oxidation is the main factor which limits the shelf-life of meat when held under frozen storage. Research undertaken used pork phospholipid liposomes as a model for studying lipid oxidation in meat. Oxidation was followed by monitoring the decrease in the phospholipid unsaturated fatty acyl chains. It was found that the greater the level of unsaturation of the phospholipid fatty acyl chain the greater was their susceptibility to peroxidation. However, the results were not consistent and several reasons for the variation in rate are provided. At ambient temperatures copper (II) was found

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Sickler, Marsha Lynn. "Inhibition of Lipid Oxidation with Phosphates in Muscle Foods." Thesis, Virginia Tech, 2000. http://hdl.handle.net/10919/9866.

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Lipid oxidation degrades the quality and decreases the shelf-stability of muscle foods. The depletion of phosphates prior to cooking may be a major factor in this undesirable reaction. Thus, the effects on lipid oxidation with the use of an encapsulate to protect the phosphates during raw storage was investigated. Unencapsulated and encapsulated sodium tripolyphosphate (STP) and sodium acid pyrophosphate (SAPP), at a level of 0.5%, were compared to control samples in cooked, ground beef patties at 0 and 6 days. The unencapsulated and encapsulated treated samples were different (P<0.05) from th

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Romain, Cindy. "Effets et recherche de mécanismes d'action d'un extrait de sarments de vigne et de vins rouges riches en resvératrol et ses oligomères : Quel rôle dans la prévention des maladies cardio-vasculaires ?" Thesis, Montpellier 2, 2013. http://www.theses.fr/2013MON20199/document.

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Les maladies cardiovasculaires (MCV) sont en augmentation au niveau mondial et sont désormais un problème de santé publique coûteux. La suralimentation et le manque d'activité physique sont des facteurs clé dans le développement pathologique. Ces dernières années, les études sur la pathogenèse des MCV ont mis en évidence de nombreux facteurs contribuant au développement de ces pathologies complexes, notamment le surpoids, l'obésité centrale, le stress oxydant, l'inflammation vasculaire et systémique, la résistance à l'insuline ou encore la dysfonction endothéliale. La prévention de ces désordr

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Zopyrus, Nadia. "On the Origin of Secosterols Upon Oxidation of Cholesterol." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35885.

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Cholesterol is one of the most abundant lipids in the body, and like all unsaturated lipids, it can be oxidized by a variety of reactive oxygen species (ROS). Lipid peroxidation is one of the main pathways by which ROS induce oxidative damage, and has been linked to neurodegenerative and cardiovascular diseases. In 2003, Wentworth et al. detected both 3β-hydroxy-5-oxo-5,6-secocholestan-6-al (secosterol-A) and its intramolecular aldolization product 3β-hydroxy-5β-hydroxy-B-norcholestane-6β-carboxaldehyde (secosterol-B) in human atherosclerotic plaques – compounds which, at the time, were only k

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Irankunda, Rachel. "Nickel Chelating Peptides & Chromatography : From Peptides Separation Simulation up to their Antioxidant Activities - related Applications." Electronic Thesis or Diss., Université de Lorraine, 2023. http://www.theses.fr/2023LORR0213.

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Les peptides chélateurs de métaux (PCMs), issus d'hydrolysats de protéines, présentent diverses applications dans les domaines de la nutrition, de la pharmacie, des cosmétiques, etc. Cependant, l'approche empirique généralement utilisée pour découvrir des peptides bioactifs à partir d'hydrolysats est longue et coûteuse en raison de nombreuses étapes de fractionnement, de séparation et d'évaluation des activités biologiques. Cette thèse a donc pour but de développer une nouvelle approche pour la prédiction de la séparation des PCMs en utilisant la modélisation et la simulation chromatographique

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Afonso, Milessa da Silva. "Avaliação do efeito do extrato aquoso e da fração fenólica livre do Alecrim (Rosmarinus officinalis L.) sobre o estado antioxidante e o perfil lipídico em ratos com hipercolesterolemia induzida pela dieta." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-17012011-163651/.

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A hipercolesterolemia é considerada um importante fator de risco para as doenças cardiovasculares, já que a hiperlipidemia associada ao estresse oxidativo é um dos fatores para estabelecimento destas doenças. Neste contexto, antioxidantes presentes em alimentos como vitaminas, compostos fenólicos, entre outros têm recebido crescente atenção devido sua função quimiopreventiva contra danos oxidativos. O alecrim (Rosmarinus officinalis L.) é um membro da família Labiatae, cujas propriedades antioxidantes têm sido atribuídas a uma variedade de compostos fenólicos capazes de finalizar as reações de

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Costa, Inês Henriques da Silva e. "Nanotoxicologia: métodos para avaliação do perfil toxicológico de sistemas nanoparticulares." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4085.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>A nanotecnologia é uma ciência promissora em diversas áreas, incluindo a indústria farmacêutica, na qual o seu principal objetivo é o desenvolvimento de novas terapias. As nanopartículas lipídicas sólidas (SLN) foram desenvolvidas com o objetivo de ultrapassar os limites dos sistemas coloidais tradicionais como lipossomas, emulsões e as nanopartículas poliméricas. São partículas com tamanhos inferiores ao mícron, entre 50-1000nm,

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