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Journal articles on the topic 'Oxidative hair dye'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Yin, Jun, and Ying Hu. "Study on Hair Dyeing Wastewater Treatment by the Union Process of Adsorption Coagulation and Potassium Permanganate Oxide." Applied Mechanics and Materials 675-677 (October 2014): 638–42. http://dx.doi.org/10.4028/www.scientific.net/amm.675-677.638.

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The amount of hair dye wastewater largest stage formed by oxidative hair dye in terms of quantity and quality, there is a serious pollution problem in the aquatic environment. Through analysis of the main component of hair dye to verify the use of activated carbon adsorption - Coagulation - potassium permanganate oxidation technology of wastewater treatment which is effective measures.According to different types of hair dye,about 80% of the market demand oxidative hair dye brown was selected to study. The results showed that the COD of 2427mg / L, the chromaticity of the hair 1000 times wastewater using 1300mg / L activated carbon adsorption treatment alone, the removal rates were 37.79%, 18.29%; in this condition and 140mg / L of mixed PAC condensate combined treatment, removal rates were 90.09%, 90.56%; potassium permanganate solution 70mg / L continues oxidation treatment, the removal rate reached 90.34 %, 97.37 %.

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2

Gama, Robson M., Simone A. França‐Stefoni, Tânia C. Sá‐Dias, Valcinir Bedin, André R. Baby, and Maria Valéria R. Velasco. "Protective effect of conditioner agents on hair treated with oxidative hair dye." Journal of Cosmetic Dermatology 17, no. 6 (January 7, 2018): 1090–95. http://dx.doi.org/10.1111/jocd.12484.

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3

Burnett, Christina L., Bart Heldreth, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, et al. "Safety Assessment of 6-Hydroxyindole as Used in Cosmetics." International Journal of Toxicology 33, no. 3_suppl (September 2014): 24S—35S. http://dx.doi.org/10.1177/1091581814533972.

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The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of 6-hydroxyindole, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that 6-hydroxyindole is safe for use in oxidative hair dye formulations.

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4

Becker, Lillian C., Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, et al. "Safety Assessment of Hydroxypropyl Bis(N-Hydroxyethyl-p-Phenylenediamine) HCl as Used in Cosmetics." International Journal of Toxicology 35, no. 2_suppl (August 11, 2016): 5S—11S. http://dx.doi.org/10.1177/1091581816659258.

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The Cosmetic Ingredient Review Expert Panel (CIR Panel) reviewed the safety of hydroxypropyl bis( N-Hydroxyethyl- p-Phenylenediamine) HCl, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that hydroxypropyl bis( N-hydroxyethyl- p-phenylenediamine) HCl is safe for use in oxidative hair dye formulations as described in this safety assessment.

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5

Burnett, Christina L., Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, et al. "Safety Assessment of 2-Amino-3-Hydroxypyridine as Used in Cosmetics." International Journal of Toxicology 39, no. 2_suppl (September 2020): 91S—97S. http://dx.doi.org/10.1177/1091581820952376.

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The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 2-Amino-3-Hydroxypyridine, which is reported to function as an oxidative hair dye ingredient. The Panel reviewed relevant animal and human data provided in this safety assessment, and concluded that 2-Amino-3-Hydroxypyridine is safe in the present practices of use and concentration for use in oxidative hair dye formulations.

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6

da Gama, Robson Miranda, Tatiana Santana Balogh, Simone França, Tânia Cristina Sá Dias, Valcinir Bedin, André Rolim Baby, Jivaldo do Rosário Matos, and Maria Valéria Robles Velasco. "Thermal analysis of hair treated with oxidative hair dye under influence of conditioners agents." Journal of Thermal Analysis and Calorimetry 106, no. 2 (March 27, 2011): 399–405. http://dx.doi.org/10.1007/s10973-011-1463-3.

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7

Murata, M. "J211 Oxidative DNA damage by hair dye meta-phenylenediamine derivatives." SANGYO EISEIGAKU ZASSHI 41, Special (1999): 541. http://dx.doi.org/10.1539/sangyoeisei.kj00001991297.

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8

Antelmi, Annarita, Magnus Bruze, Erik Zimerson, Malin Engfeldt, Ewa Young, Lena Persson, Caterina Foti, Östen Sörensen, and Cecilia Svedman. "Evaluation of concordance between labelling and content of 52 hair dye products: overview of the market of oxidative hair dye." European Journal of Dermatology 27, no. 2 (March 2017): 123–31. http://dx.doi.org/10.1684/ejd.2016.2934.

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9

., Mohammad A. M. Wadaan. "Blood Chemistry of Domestic Rabbits Exposed to an Oxidative Hair Dye." International Journal of Pharmacology 2, no. 4 (June 15, 2006): 431–34. http://dx.doi.org/10.3923/ijp.2006.431.434.

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10

ZUO, Xue, Zheng DI, Rong ZHANG, and Guoqing WU. "Simultaneous determination of 33 hair dyes in oxidative hair dye products by high performance liquid chromatography." Chinese Journal of Chromatography 37, no. 7 (2019): 759. http://dx.doi.org/10.3724/sp.j.1123.2019.01043.

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11

Burnett, Christina L., Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel Liebler, James G. Marks, et al. "Safety Assessment of 2-Amino-4-Hydroxyethylaminoanisole and 2-Amino-4-Hydroxyethylaminoanisole Sulfate as Used in Cosmetics." International Journal of Toxicology 32, no. 3_suppl (May 2013): 25S—35S. http://dx.doi.org/10.1177/1091581813486301.

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2-Amino-4-hydroxyethylaminoanisole and its salt, 2-amino-4-hydroxyethylaminoanisole sulfate, are used as coupling agents in oxidative hair dyes. The Cosmetic Ingredient Review Expert Panel reviewed relevant animal and human data related to the ingredient. The Expert Panel concluded that 2-amino-4-hydroxyethylaminoanisole and 2-amino-4-hydroxyethylaminoanisole sulfate are safe for use in oxidative hair dye formulations. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed.

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12

Kim, Hyunji, and Kisok Kim. "Prevalence of potent skin sensitizers in oxidative hair dye products in Korea." Cutaneous and Ocular Toxicology 35, no. 3 (August 24, 2015): 204–7. http://dx.doi.org/10.3109/15569527.2015.1076434.

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13

., Mohammad A. M. Wadaan, and Mohammad Mubarak . "Effect of an Oxidative Hair Dye on the Skin of Domestic Rabbits." Journal of Biological Sciences 5, no. 6 (October 15, 2005): 809–12. http://dx.doi.org/10.3923/jbs.2005.809.812.

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14

Yazar, Kerem, Anders Boman, and Carola Lidén. "Potent skin sensitizers in oxidative hair dye products on the Swedish market." Contact Dermatitis 61, no. 5 (November 2009): 269–75. http://dx.doi.org/10.1111/j.1600-0536.2009.01612.x.

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15

Iwata, Jun-ichi, Naoko Inomata, Megumi Sato, Mami Miyakawa, Toshiko Kawaguchi, and Michiko Aihara. "Contact dermatitis with concomitant contact urticaria syndrome due to multiple ingredients of oxidative hair dye." Allergology International 68, no. 1 (January 2019): 114–16. http://dx.doi.org/10.1016/j.alit.2018.05.005.

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16

Hedberg, Yolanda S., Wolfgang Uter, Piu Banerjee, Marie-Louise Lind, Sanne Skovvang Steengaard, Ying Teo, and Carola Lidén. "Non-oxidative hair dye products on the European market: What do they contain?" Contact Dermatitis 79, no. 5 (July 20, 2018): 281–87. http://dx.doi.org/10.1111/cod.13074.

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17

Bracher, Max, Claudine Faller, Wolfgang Grötsch, Richard Marshall, and Jochen Spengler. "Studies on the potential mutagenicity of p-phenylenediamine in oxidative hair dye mixtures." Mutation Research/Genetic Toxicology 241, no. 3 (July 1990): 313–23. http://dx.doi.org/10.1016/0165-1218(90)90030-6.

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18

Schuh, Verner. "8 Safety assessment of oxidative hair dye products - the challenge of evaluating reactive mixtures." Toxicology Letters 144 (September 2003): s3. http://dx.doi.org/10.1016/s0378-4274(03)90007-5.

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19

Tokuda, Hajime, Yukio Kimura, and Satoshi Takano. "Determination of dye intermediates in oxidative hair dyes by fused-silica capillary gas chromatography." Journal of Chromatography A 367 (January 1986): 345–56. http://dx.doi.org/10.1016/s0021-9673(00)94855-6.

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20

Pel, E., G. Bordin, and A. R. Rodriguez. "HPLC Candidate Reference Method for Oxidative Hair Dye Analysis. I. Separation and Stability Testing." Journal of Liquid Chromatography & Related Technologies 21, no. 6 (March 1998): 883–901. http://dx.doi.org/10.1080/10826079808000516.

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21

Velasco, Maria Valéria Robles, Simone Rachid Pfannemüller de Abreu, Anderson Zanardi de Freitas, Valcinir Bedin, André Rolim Baby, and Robson Miranda da Gama. "Optical coherence tomography to evaluate the effects of oxidative hair dye on the fiber." Skin Research and Technology 22, no. 4 (January 21, 2016): 430–36. http://dx.doi.org/10.1111/srt.12283.

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22

Uehara, Saori, Naoko Inomata, Aki Suzuki, Midori Matsuura, and Michiko Aihara. "Severe contact urticarial syndrome due to oxidative hair dye containing para-aminophenol and sodium-methyl-oleoyl-taurate." Journal of Dermatology 41, no. 6 (June 2014): 560–61. http://dx.doi.org/10.1111/1346-8138.12489.

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23

Lewis, David, John Mama, and Jamie Hawkes. "A Review of Aspects of Oxidative Hair Dye Chemistry with Special Reference to N-Nitrosamine Formation." Materials 6, no. 2 (February 13, 2013): 517–34. http://dx.doi.org/10.3390/ma6020517.

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24

Murata, Mariko, Tomoko Nishimura, Fang Chen, and Shosuke Kawanishi. "Oxidative DNA damage induced by hair dye components ortho-phenylenediamines and the enhancement by superoxide dismutase." Mutation Research/Genetic Toxicology and Environmental Mutagenesis 607, no. 2 (September 2006): 184–91. http://dx.doi.org/10.1016/j.mrgentox.2006.04.014.

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25

Li, D., Y. Huang, and J. Su. "Dyeing behaviours of amino heterocyclic compounds as blue oxidative hair dye precursors applied to keratin fibres." International Journal of Cosmetic Science 33, no. 2 (January 25, 2011): 183–89. http://dx.doi.org/10.1111/j.1468-2494.2010.00615.x.

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26

King, Thomas, Ruth Sabroe, and Catherine Holden. "Allergic contact dermatitis caused by 1-naphthol, a red coupler, in a purple permanent oxidative hair dye." Contact Dermatitis 79, no. 2 (March 25, 2018): 99–100. http://dx.doi.org/10.1111/cod.12997.

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27

Wang, Lai-Hao, and Shu-Jen Tsai. "Simultaneous determination of oxidative hair dye p-phenylenediamine and its metabolites in human and rabbit biological fluids." Analytical Biochemistry 312, no. 2 (January 2003): 201–7. http://dx.doi.org/10.1016/s0003-2697(02)00501-8.

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28

Lee, Jae Kwon, Hye Eun Lee, Gabsik Yang, Kyu-Bong Kim, Seung Jun Kwack, and Joo Young Lee. "Para-phenylenediamine, an oxidative hair dye ingredient, increases thymic stromal lymphopoietin and proinflammatory cytokines causing acute dermatitis." Toxicological Research 36, no. 4 (February 21, 2020): 329–36. http://dx.doi.org/10.1007/s43188-020-00041-6.

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29

Andersen, F. Alan. "Final Report On the Safety Assessment of 2-Amino-6-Chloro-4-Nitrophenol and 2-Amino-6-Chloro-4-Nitrophenol Hydrochloride1." International Journal of Toxicology 16, no. 1_suppl (January 1997): 131–43. http://dx.doi.org/10.1177/109158189701600108.

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2-Amino-6-Chloro-4-Nitrophenol and its hydrochloride salt are substituted aromatic compounds that function as colorants in hair dyes. Only the hydrochloride salt is currently reported to be used. 2-Amino-6-Chloro-4-Nitrophenol is poorly absorbed through the skin. Less than 0.25% of 2-Amino-6-Chloro-4-Nitrophenol found in a nonoxidative hair dye was absorbed. Less than 0.2% of 2-Amino-6-Chloro-4-Nitrophenol found in an oxidative hair dye was absorbed. In subchronic oral studies in rats, a no observable adverse effect level of 30 mg / kg / day for 2-Amino-6-Chloro-4-Nitrophenol was determined; at higher doses, increased organ weights were seen. A 2% solution of 2-Amino-6-Chloro-4-Nitrophenol applied under occlusive conditions was found to be nonirritating to rabbits. At 0.1%, 2-Amino-6-Chloro-4-Nitrophenol was nonsensitizing; at 2%, there was sufficient skin coloration from the dye that assessment of sensitization was difficult; but no obviously sensitized areas were reported. An oral teratogenicity study in rats showed no birth defects. In one Ames test, Salmonella strains TA97, TA98, and TA100 showed an increase in mutations, with and without metabolic activations. Strain TA1535 was negative, however. In another Ames test, Salmonella strains TA97 and TA100 showed no increase in mutations upon treatment with 2-Amino-6-Chloro-4-Nitrophenol, diluted in dimethylsulfoxide, with and without metabolic activation. Strain TA98 was negative with metabolic activation but positive without activation. In follow-up testing with strain TA98-NR, there was no increase in mutations in the absence of activation. Mutagenicity assays in mammalian systems were negative. The poor absorption through the skin, lack of any teratogenic effect, and negative mutagenesis data in certain Ames test strains and in mammalian systems suggested that any systemic effects from the use of actual products were unlikely. It was possible to conclude that the highest concentration of 2-Amino-6-Chloro-4-Nitrophenol tested (2%) is safe for use in hair dye formulations.

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30

Suzuki, T., Y. Masui, A. Ito, and R. Abe. "354 Consumer self-testing of coloring mixtures is not useful for prediction of oxidative hair dye-related contact allergy." Journal of Investigative Dermatology 137, no. 5 (May 2017): S61. http://dx.doi.org/10.1016/j.jid.2017.02.371.

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31

Nohynek, Gerhard J., Julie A. Skare, Wim J. A. Meuling, David W. Hein, Albert Th H. J. de Bie, and Herve Toutain. "Urinary acetylated metabolites and N-acetyltransferase-2 genotype in human subjects treated with a para-phenylenediamine-containing oxidative hair dye." Food and Chemical Toxicology 42, no. 11 (November 2004): 1885–91. http://dx.doi.org/10.1016/j.fct.2004.07.009.

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32

Abdelmoniem, Amr M., Mohamed H. Elnagdi, Mohamed S. Elsehemy, Hesham R. El-Seedi, and Ismail A. Abdelhamid. "Synthesis, Chemistry and Utilities of Diaminoazoles with Special Reference to 3,5-diaminopyrazoles." Current Organic Synthesis 15, no. 4 (June 12, 2018): 487–514. http://dx.doi.org/10.2174/1570179415666180403120140.

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Background: Although the chemistry of heteroaromatic monoamino azoles has been surveyed more than once in the last decade, the chemistry of the di- and triaminoazoles has not been reviewed. In this article we will survey the synthesis, chemistry and utility of the diaminoazoles. In this review, the chemistry of the diaminoazoles as well as their most important utilities will be surveyed. Objective: The review focuses on recent progress in diaminoazoles (i.e. diaminopyrazoles, diaminoimidazoles, diaminotriazoles and diaminothiazole) with especial references to diaminopyrazoles. The synthesis as well as pharmaceutical utilities are reported. There are several methods for synthesis of diaminopyrazoles. 3,5- Diaminopyrazole and its derivatives are prepared through the reaction of malononitrile or arylhydrazononitrile with hydrazine derivatives. 3,4-Diaminopyrazoles are prepared via nitration of 3-aminopyrazole with subsequent reduction of the produced compound. The diaminopyrazoles have several applications in cosmetic and pharmaceutical industries. They also have useful utilities as a constituent in oxidative hair dyes. Conclusion: We managed to report the common methods for the synthesis of diaminoazoles with especial reference to aminopyrazoles that are prepared through the reaction of malononitrile or hydrazononitriles with hydrazine derivatives. Some important applications that include pharmaceutical utilities such as hair dye constituents are reported.

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33

Goebel, C., E. M. Gargano, A. A. Gaspari, and B. Blömeke. "Reduced risk of allergy induction for hairdressers? An occupational risk assessment for the new oxidative hair dye 2-methoxymethyl-p-phenylenediamine." Toxicology Letters 295 (October 2018): S184—S185. http://dx.doi.org/10.1016/j.toxlet.2018.06.842.

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34

Kojima, T., H. Yamada, Y. Saito, T. Nawa, M. Isobe, T. Yamamoto, D. Aoki, Y. Matsushita, and K. Fukushima. "Investigation of dyeing behavior of oxidative dye in fine structures of the human hair cuticle by nanoscale secondary ion mass spectrometry." Skin Research and Technology 21, no. 3 (October 17, 2014): 295–301. http://dx.doi.org/10.1111/srt.12192.

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35

Park, Hanseul, Jee-hyun Hwang, Ji-Seok Han, Byoung-Seok Lee, Yong-Bum Kim, Kyung-Mi Joo, Min-Seok Choi, Sun-A. Cho, Bae-Hwan Kim, and Kyung-Min Lim. "Skin irritation and sensitization potential of oxidative hair dye substances evaluated with in vitro, in chemico and in silico test methods." Food and Chemical Toxicology 121 (November 2018): 360–66. http://dx.doi.org/10.1016/j.fct.2018.09.017.

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36

Martini, Mary C. "Spengler J, Bracher M: Toxicological tests and health risk assessment of oxidative hair dye mixtures. Cosmetics & Toiletries 105:67-76, 1990." Dermatitis 1, no. 4 (December 1990): 256. http://dx.doi.org/10.1097/01206501-199012000-00017.

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37

Martini, Mary C. "Spengler J, Bracher M: Toxicological tests and health risk assessment of oxidative hair dye mixtures. Cosmetics & Toiletries 105:67-76, 1990." American Journal of Contact Dermatitis 1, no. 4 (December 1990): 256. http://dx.doi.org/10.1097/01634989-199012000-00017.

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38

Oh, Jae-Young, Bo-Mi Ryu, Hye-Won Yang, Eun-A. Kim, Jung-Suck Lee, and You-Jin Jeon. "Protective effects of Ecklonia cava extract on the toxicity and oxidative stress induced by hair dye in in-vitro and in-vivo models." Journal of Oceanology and Limnology 37, no. 3 (May 2019): 909–17. http://dx.doi.org/10.1007/s00343-019-8148-3.

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39

Ávila, Renato I., Thaisângela L. Rodrigues, and Marize C. Valadares. "Effects of hair dye ingredients on the oxidative stress response: Modulation of the mRNA expressions of NRF2 , HO‐1 , and FOS in HaCaT keratinocytes." Contact Dermatitis 82, no. 5 (February 6, 2020): 332–34. http://dx.doi.org/10.1111/cod.13478.

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40

Hueber-Becker, Frédérique, Gerhard J. Nohynek, Wim J. A. Meuling, Florence Benech-Kieffer, and Hervé Toutain. "Human systemic exposure to a [14C]-para-phenylenediamine-containing oxidative hair dye and correlation with in vitro percutaneous absorption in human or pig skin." Food and Chemical Toxicology 42, no. 8 (August 2004): 1227–36. http://dx.doi.org/10.1016/j.fct.2004.02.020.

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41

Motz-Schalck, Laurence, and Jacques Lemaire. "Fading modelling of a hair oxidation dye: aminoindamine." Journal of Photochemistry and Photobiology A: Chemistry 147, no. 3 (April 2002): 233–39. http://dx.doi.org/10.1016/s1010-6030(01)00616-5.

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42

Nishikawa, S., and F. Sasaki. "Internalization of styryl dye FM1-43 in the hair cells of lateral line organs in Xenopus larvae." Journal of Histochemistry & Cytochemistry 44, no. 7 (July 1996): 733–41. http://dx.doi.org/10.1177/44.7.8675994.

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We used a fluorescent dye, FM1-43 to investigate mechanotransduction mechanisms in the hair cells of lateral line organs of Xenopus larvae. FM1-43 specifically labeled the hair cells. The photo-oxidation technique was performed with election microscopy to examine the labeling sites and their mechanisms. The results showed that the labeling sites were mitochondria and rough endoplasmic reticulum throughout the cytoplasm. Endocytic activity of the hair cells was limited to endosomes and small granules located at the apical part of the cells. Blockers of the mechanosensitive cation channel (neomycin, gentamicin, streptomycin, and amiloride) effectively inhibited FM1-43 labeling. One of the blockers, amiloride, was found to bind to hair cells when its fluorescence was examined. Divalent cations such as Mg2+ and Ca2+, but not monovalent cations such as Na+ and K+, inhibited FM1-43 labeling when they were added in excess amounts. These results suggest that FM1-43 internalizes hair cells via the putative mechanosensitive cation channel in the plasma membrane.

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43

Venkatesan, Gopalakrishnan, Yuri Dancik, Arup Sinha, Mei Bigliardi, Ramasamy Srinivas, Thomas Dawson, Suresh Valiyaveettil, Paul Bigliardi, and Giorgia Pastorin. "Facile synthesis of oligo anilines as permanent hair dyes: how chemical modifications impart colour and avoid toxicity." New Journal of Chemistry 43, no. 41 (2019): 16188–99. http://dx.doi.org/10.1039/c9nj03362a.

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44

Waqas, Muhammad, Song Gao, Iram-us-Salam, Muhammad Kazim Ali, Yongming Ma, and Wenyan Li. "Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage." Neural Plasticity 2018 (July 15, 2018): 1–9. http://dx.doi.org/10.1155/2018/3170801.

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Inner ear hair cells are mechanosensory receptors that perceive mechanical sound and help to decode the sound in order to understand spoken language. Exposure to intense noise may result in the damage to the inner ear hair cells, causing noise-induced hearing loss (NIHL). Particularly, the outer hair cells are the first and the most affected cells in NIHL. After acoustic trauma, hair cells lose their structural integrity and initiate a self-deterioration process due to the oxidative stress. The activation of different cellular death pathways leads to complete hair cell death. This review specifically presents the current understanding of the mechanism exists behind the loss of inner ear hair cell in the auditory portion after noise-induced trauma. The article also explains the recent hair cell protection strategies to prevent the damage and restore hearing function in mammals.

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45

ARAI, Yasuhiro, Kimio OHNO, and Uhei TAMURA. "Effect of oils in oxidation Hair Dye on Its Dyeing Ability." Journal of the Japan Society of Colour Material 72, no. 1 (1999): 19–24. http://dx.doi.org/10.4011/shikizai1937.72.19.

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46

Park, Dong Jun, Sunmok Ha, Jin Sil Choi, Su Hoon Lee, Jeong-Eun Park, and Young Joon Seo. "Induced Short-Term Hearing Loss due to Stimulation of Age-Related Factors by Intermittent Hypoxia, High-Fat Diet, and Galactose Injection." International Journal of Molecular Sciences 21, no. 19 (September 25, 2020): 7068. http://dx.doi.org/10.3390/ijms21197068.

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Age-related hearing loss (ARHL) is the most common sensory disorder among the elderly, associated with aging and auditory hair cell death due to oxidative-stress-induced mitochondrial dysfunction. Although transgenic mice and long-term aging induction cultures have been used to study ARHL, there are currently no ARHL animal models that can be stimulated by intermittent environmental changes. In this study, an ARHL animal model was established by inducing continuous oxidative stress to promote short-term aging of cells, determined on the basis of expression of hearing-loss-induced phenotypes and aging-related factors. The incidence of hearing loss was significantly higher in dual- and triple-exposure conditions than in intermittent hypoxic conditions, high-fat diet (HFD), or d-galactose injection alone. Continuous oxidative stress and HFD accelerated cellular aging. An increase in Ucp2, usually expressed during mitochondrial dysfunction, was observed. Expression of Cdh23, Slc26a4, Kcnq4, Myo7a, and Myo6, which are ARHL-related factors, were modified by oxidative stress in the cells of the hearing organ. We found that intermittent hypoxia, HFD, and galactose injection accelerated cellular aging in the short term. Thus, we anticipate that the development of this hearing loss animal model, which reflects the effects of intermittent environmental changes, will benefit future research on ARHL.

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47

Kamin, Dirk, Natalia H. Revelo, and Silvio O. Rizzoli. "FM Dye Photo-Oxidation as a Tool for Monitoring Membrane Recycling in Inner Hair Cells." PLoS ONE 9, no. 2 (February 5, 2014): e88353. http://dx.doi.org/10.1371/journal.pone.0088353.

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48

Lee, Jun-Uk, Yong-Won Ma, Sung-Yeob Jeong, and Bo-Sung Shin. "Direct Fabrication of Ultra-Sensitive Humidity Sensor Based on Hair-Like Laser-Induced Graphene Patterns." Micromachines 11, no. 5 (April 30, 2020): 476. http://dx.doi.org/10.3390/mi11050476.

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Three-dimensional (3-D) porous graphitic structures have great potential for sensing applications due to their conductive carbon networks and large surface area. In this work, we present a method for facile fabrication of hair-like laser induced graphene (LIG) patterns using a laser scribing system equipped with a 355 nm pulsed laser. The polyimide (PI) film was positioned on a defocused plane and irradiated at a slow scanning speed using a misaligned laser beam. These patterns have the advantages of a large surface area and abundant oxidation groups. We have applied the hair-like LIG patterns to a humidity sensor. The humidity sensor showed good sensitivity characteristics and a large amount of electronic carriers can be stored.

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Tanada, Norihiko, Seiichi Kashimura, Mitsuyoshi Kageura, and Kenji Hara. "Practical GC/MS Analysis of Oxidation Dye Components in Hair Fiber as a Forensic Investigative Procedure." Journal of Forensic Sciences 44, no. 2 (March 1, 1999): 14454J. http://dx.doi.org/10.1520/jfs14454j.

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Nam, Youn Hee, Isabel Rodriguez, Seo Yeon Jeong, Thu Nguyen Minh Pham, Wanlapa Nuankaew, Yun Hee Kim, Rodrigo Castañeda, et al. "Avocado Oil Extract Modulates Auditory Hair Cell Function through the Regulation of Amino Acid Biosynthesis Genes." Nutrients 11, no. 1 (January 8, 2019): 113. http://dx.doi.org/10.3390/nu11010113.

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Sensorineural hearing loss (SNHL) is one of the most common causes of disability, affecting over 466 million people worldwide. However, prevention or therapy of SNHL has not been widely studied. Avocado oil has shown many health benefits but it has not yet been studied in regards to SNHL. Therefore, we aimed to investigate the efficacy of avocado oil on SNHL in vitro and in vivo and elucidate its mode of action. For the present study, we used enhanced functional avocado oil extract (DKB122). DKB122 led to recovery of otic hair cells in zebrafish after neomycin-induced otic cell damage. Also, DKB122 improved auditory sensory transmission function in a mouse model of noise induced-hearing loss and protected sensory hair cells in the cochlea. In addition, RNA sequencing was performed to elucidate the mechanism involved. KEGG pathway enrichment analysis of differentially expressed genes showed that DKB122 protected House Ear Institute-Organ of Corti 1 (HEI-OC1) cells against neomycin-related alterations in gene expression due to oxidative stress, cytokine production and protein synthesis.

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