Academic literature on the topic 'Oxidative modulation'

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Journal articles on the topic "Oxidative modulation"

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Janero, D. R., and C. Yarwood. "Oxidative modulation and inactivation of rabbit cardiac adenylate deaminase." Biochemical Journal 306, no. 2 (1995): 421–27. http://dx.doi.org/10.1042/bj3060421.

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Oxidative stress and adenine nucleotide catabolism occur concomitantly in several disease states, such as cardiac ischaemia-reperfusion, and may act as synergistic determinants of tissue injury. However, the mechanisms underlying this potential interaction remain ill-defined. We examined the influence of oxidative stress on the molecular, kinetic and regulatory properties of a ubiquitous AMP-catabolizing enzyme, adenylate deaminase (AMPD) (EC 3.5.4.6). To this intent, rabbit heart AMPD and an H2O2/ascorbate/iron oxidation system were employed. Enzyme exposure to the complete oxidation system a
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Santos, Leonardo, Carlos Escande, and Ana Denicola. "Potential Modulation of Sirtuins by Oxidative Stress." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/9831825.

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Sirtuins are a conserved family of NAD-dependent protein deacylases. Initially proposed as histone deacetylases, it is now known that they act on a variety of proteins including transcription factors and metabolic enzymes, having a key role in the regulation of cellular homeostasis. Seven isoforms are identified in mammals (SIRT1–7), all of them sharing a conserved catalytic core and showing differential subcellular localization and activities. Oxidative stress can affect the activity of sirtuins at different levels: expression, posttranslational modifications, protein-protein interactions, an
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da Palma, Renata K., Ivana C. Moraes-Silva, Danielle da Silva Dias, et al. "Resistance or aerobic training decreases blood pressure and improves cardiovascular autonomic control and oxidative stress in hypertensive menopausal rats." Journal of Applied Physiology 121, no. 4 (2016): 1032–38. http://dx.doi.org/10.1152/japplphysiol.00130.2016.

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We investigated whether resistance training (RT) vs. aerobic training (AT) differentially impacts on arterial pressure and related mechanisms in ovariectomized spontaneously hypertensive rats (SHRs). Female SHRs were ovariectomized and assigned to one of the following groups: sedentary, AT, or RT; sham sedentary SHR were used as control group. AT was performed on a treadmill, whereas RT was performed on a vertical ladder. Both exercise protocols were performed for 8 wk, 5 days/wk. Arterial pressure, baroreflex sensitivity, autonomic modulation, and cardiac oxidative stress parameters (lipid pe
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Hondorp, Elise R., and Rowena G. Matthews. "Oxidation of Cysteine 645 of Cobalamin-Independent Methionine Synthase Causes a Methionine Limitation in Escherichia coli." Journal of Bacteriology 191, no. 10 (2009): 3407–10. http://dx.doi.org/10.1128/jb.01722-08.

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ABSTRACT Cobalamin-independent methionine synthase (MetE) catalyzes the final step in Escherichia coli methionine biosynthesis but is inactivated under oxidative conditions, triggering a methionine deficiency. This study demonstrates that the mutation of MetE cysteine 645 to alanine completely eliminates the methionine auxotrophy imposed by diamide treatment, suggesting that modulation of MetE activity via cysteine 645 oxidation has significant physiological consequences for oxidatively stressed cells.
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Lawlor, Susan M., та Nora M. O'brien. "Modulation of oxidative stress by β-carotene in chicken embryo fibroblasts". British Journal of Nutrition 73, № 6 (1995): 841–50. http://dx.doi.org/10.1079/bjn19950089.

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The ability of β-carotene to protect against oxidative stressin vitrowas assessed. Primary cultures of chicken embryo fibroblasts (CEF) were oxidatively stressed by exposure to paraquat (PQ). Activities of the antioxidant enzymes superoxide dismutase (SOD;EC1.15.1.1), catalase (CAT;EC1.11.1.6) and glutathione peroxidase (GSH-Px;EC1.11.1.9) were measured as indices of oxidative stress. CEF incubated with 0·25 mM-PQ for 18 h exhibited increased SOD and CAT activities and decreased GSH-Px activity compared with the control (P< 0·001). Incorporation of added β-carotene (0·1 μM) into 0·25 mM-PQ-
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Singh, Prabhakar, and Syed Ibrahim Rizvi. "Modulation Effects of Curcumin on Erythrocyte Ion-Transporter Activity." International Journal of Cell Biology 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/630246.

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Curcumin ((1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), the yellow biphenolic pigment isolated from turmeric (Curcuma longa), has various medicinal benefits through antioxidation, anti-inflammation, cardiovascular protection, immunomodulation, enhancing of the apoptotic process, and antiangiogenic property. We explored the effects of curcuminin vitro(10−5 M to 10−8 M) andin vivo(340 and 170 mg/kg b.w., oral) on Na+/K+ATPase (NKA), Na+/H+exchanger (NHE) activity, and membrane lipid hydroperoxides (ROOH) in control and experimental oxidative stress erythrocytes of Wistar
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Carlesi, C., E. Caldarazzo Ienco, S. Piazza, et al. "Oxidative stress modulation in neurodegenerative diseases." Mediterranean Journal of Nutrition and Metabolism 4, no. 3 (2011): 219–25. http://dx.doi.org/10.3233/s12349-011-0053-z.

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Zima, Tom??&OV0165;, Emanuele Albano, Magnus Ingelman-Sundberg, et al. "Modulation of Oxidative Stress by Alcohol." Alcoholism: Clinical & Experimental Research 29, no. 6 (2005): 1060–65. http://dx.doi.org/10.1097/01.alc.0000168168.43419.54.

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Alamdari, Daryoush Hamidi, Malektaj Honarmand, Abdolfattah Sarrafnejad, et al. "Oxidative Stress Modulation Immediately After Hemodialysis." Dialysis & Transplantation 38, no. 9 (2009): 354–58. http://dx.doi.org/10.1002/dat.20345.

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Da Costa, Laura A., Alaa Badawi, and Ahmed El-Sohemy. "Nutrigenetics and Modulation of Oxidative Stress." Annals of Nutrition and Metabolism 60, s3 (2012): 27–36. http://dx.doi.org/10.1159/000337311.

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Dissertations / Theses on the topic "Oxidative modulation"

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Qiao, Shuxi. "Pharmacological Modulation of Oxidative and Proteotoxic Stress for Antimelanoma Intervention." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/311348.

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Cumulative evidence suggests that constitutively elevated levels of proteotoxic stress represent a specific vulnerability of malignant cells that can be targeted by pharmacological modulation of the intracellular proteotoxic stress response. According to this emerging mechanism, small molecule stress modulators may induce deviations from protein homeostasis causing cytotoxicity confined to malignant cells already at a high set point of constitutive proteotoxic stress leading to functional impairment and even cell death. In contrast, normal cells with sufficient protein degradation capacity can
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Harris, Jessica Lynn. "INVESTIGATIONS INTO MODULATION OF BRAIN OXIDATIVE STRESS BY VARIOUS INTERVENTIONS." UKnowledge, 2012. http://uknowledge.uky.edu/chemistry_etds/12.

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In this thesis study we examined glycogen synthase kinase-3β (GSK-3β) and its effects over Nrf2 and Pin 1 as it relates to Alzheimer’s disease (AD). AD is a neurodegenerative disease characterized by a prolonged high oxidative environment. Transcription factor Nrf2 is vital in the brain’s defense against oxidative insults through its up-regulation of over 100 antioxidants. Depletion of the brain’s antioxidant defense system results in intolerance to an oxidative environment, contributing to the progression of AD. The regulatory Pin 1 protein promotes cellular homeostasis, and when down-regulat
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Bunyard, Peter Robert. "Modulation of dendritic cell maturation by ribotoxic and oxidative stress." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271744.

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Khaper, Neelam. "Modulation of oxidative stress and antioxidants by losartan in heart failure." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ62645.pdf.

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De, Haaij Yolanda. "Modulation of oxidative stress parameters in healthy volunteers by strenuous exercise." Diss., Pretoria : [s.n.], 2006. http://upetd.up.ac.za/thesis/available/etd-07312007-153855.

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Sarna, Lindsei. "Regulation of oxidative stress and its modulation by natural health products." NRC Research Press, 2010. http://hdl.handle.net/1993/30624.

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Oxidative stress is characterized by the cellular accumulation of reactive oxygen species (ROS). Increased production of ROS, such as the superoxide anion (O2.-), or a deficiency in their clearance by antioxidant defenses, mediates the cellular pathology. Non-alcoholic fatty liver disease (NAFLD) is a broad spectrum liver disorder commonly manifesting in milieu of the metabolic syndrome. Oxidative stress is an important pathogenic mediator in NAFLD, and in its associated morbidities like atherosclerosis. The objective of my research was to investigate the regulation of oxidative stress and the
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Nagam, Satya Mohan Babu. "Effect of Thyroid Modulation on Arsenic-Induced Oxidative Stress in Zebrafish." Thesis, Southern Illinois University at Edwardsville, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1549814.

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<p> It is well known that environmental contaminants such as arsenic can induce oxidative stress in fish. It is also known that thyroid hormone status affects susceptibility to oxidative stress. However, the effect of thyroid hormone status on pollutant- induced oxidative stress is unknown. This is significant, because such knowledge would help to assess the risk of xenobiotics such as arsenate, a prevalent contaminant in the environment. The interaction between arsenate- induced oxidative stress and altered thyroid hormones has not been elucidated thoroughly in previous studies. In order to a
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Ward, Nathan Patrick. "Therapeutic Modulation of Cancer Metabolism with Dichloroacetate and Metformin." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6778.

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The robust glycolytic metabolism of glioblastoma multiforme (GBM) has proven them susceptible to increases in oxidative metabolism induced by the pyruvate mimetic dichloroacetate (DCA). Recent reports demonstrate that the anti-diabetic drug metformin enhances the damaging oxidative stress associated with DCA treatment in cancer cells. We sought to elucidate the role of metformin’s reported activity as a mitochondrial complex I inhibitor in the enhancement of DCA cytotoxicity in the VM-M3 model of GBM. We demonstrated that metformin potentiated DCA-induced superoxide production and that this wa
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Elizalde, Violeta Serra. "Modulation of telomere length by oxidative stress in vitro and in vivo." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366579.

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Francisco, Ngiambudulu Mbandu. "Modulation of postprandial oxidative stress by rooibos (aspalathus linearis) in normolipidaemic individuals." Thesis, Cape Peninsula University of Technology, 2010. http://hdl.handle.net/20.500.11838/1469.

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Thesis (MTech (Biomedical Technology))--Cape Peninsula University of Technology, 2010<br>Consumption of sucrose with a meal containing oxidised and oxidisable lipids cause an increase in oxidative stress which is referred to as postprandial oxidative stress. The modulating effect on postprandial oxidative stress by an antioxidant-rich beverage, fermented rooibos (Aspalathus linearis) was compared to that of a commercial soft drink (soda). Both study beverages contained sucrose and were consumed with a standardised fat meal. The study consisted of two parts, a pilot study (Phase On
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Books on the topic "Oxidative modulation"

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Bansal, Mohinder, and Naveen Kaushal. Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9.

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Chakraborti, Sajal, Naranjan S. Dhalla, Madhu Dikshit, and Nirmal K. Ganguly, eds. Modulation of Oxidative Stress in Heart Disease. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-8946-7.

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Singh, Ranji. The modulation of NADPH, NADH, and a-ketoglutarate in Pseudomonas fluorescens exposed to oxidative stress. Laurentian University, School of Graduate Studies, 2005.

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Geoghegan, Susan M. Modulating the redox propertoes of a flavoprotein; cloning, expression and site-directed mutagenesis of flavodoxin from M. elsdenii. University College Dublin, 1997.

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Dhalla, Naranjan S., Nirmal K. Ganguly, Sajal Chakraborti, and Madhu Dikshit. Modulation of Oxidative Stress in Heart Disease. Springer, 2019.

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(Editor), Young-Joon Surh, Zigang Dong (Editor), Enrique Cadenas (Editor), and Lester Packer (Editor), eds. Dietary Modulation of Cell Signaling Pathways (Oxidative Stress and Disease). CRC, 2008.

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Zilliox, Lindsay, and James W. Russell. Diabetic and Prediabetic Neuropathy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0115.

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Impaired glucose regulation (IGR) constitutes a spectrum of impaired glucose and metabolic regulation that can result in neuropathy. Several different pathways of injury in the diabetic peripheral nervous system that include metabolic dysregulation induced by metabolic syndrome induce oxidative stress, failure of nitric oxide regulation, and dysfunction of certain key signaling pathways. Oxidative stress can directly injure both dorsal route ganglion neurons and axons. Modulation of the nitric oxide system may have detrimental effects on endothelial function and neuronal survival. Reactive oxi
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Book chapters on the topic "Oxidative modulation"

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Bansal, Mohinder, and Naveen Kaushal. "Introduction to Oxidative Stress." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_1.

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Bansal, Mohinder, and Naveen Kaushal. "Oxidative Stress in Pathogenesis." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_2.

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Bansal, Mohinder, and Naveen Kaushal. "Oxidative Stress and Carcinogenesis." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_4.

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Bansal, Mohinder, and Naveen Kaushal. "Managing Oxidative Stress/Targeting ROS." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_6.

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Bansal, Mohinder, and Naveen Kaushal. "Oxidative Stress in Metabolic Disorders/Diseases." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_3.

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Jugdutt, Bodh I., and Bernadine A. Jugdutt. "Oxidative Stress and Heart Failure." In Modulation of Oxidative Stress in Heart Disease. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-8946-7_11.

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Bansal, Mohinder, and Naveen Kaushal. "Cell Signaling and Gene Regulation by Oxidative Stress." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_5.

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Bansal, Mohinder, and Naveen Kaushal. "Selenium: A Potent Natural Antioxidant." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_7.

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Bansal, Mohinder, and Naveen Kaushal. "Future Perspective." In Oxidative Stress Mechanisms and their Modulation. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-2032-9_8.

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Djuric, Zora, Silvana Martino, Lance K. Heilbrun, and Ronald W. Hart. "Dietary Modulation of Oxidative DNA Damage." In Advances in Experimental Medicine and Biology. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-0939-8_5.

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Conference papers on the topic "Oxidative modulation"

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Bocchino, Marialuisa, Serena Zanotta, Gaetano Rea, Giorgio Emanuele Polistina, Antonietta Coppola, and Domenico Galati. "Peripheral oxidative burst correlates with VEGF serum levels in IPF: modulation by anti-fibrotic treatments." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3712.

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Leung, Man Hong, Ho Tsoi, Ellen Pui Sum Man, Eric Wing-Fai Lam, and Ui Soon Khoo. "Abstract B38: The role of BQ323636.1, a novel splice variant of NCOR2, in modulation of oxidative stress in breast cancer." In Abstracts: AACR Special Conference: Advances in Breast Cancer Research; October 7-10, 2017; Hollywood, CA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1557-3125.advbc17-b38.

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IKEYI, ADACHUKWU, INNOCENT UZOCHUKWU OKAGU, and CHRISTIANA NONYE IGWE. "Modulation of oxidative stress associated with experimentally-induced benign prostatic hyperplasia in rats by Zapoteca portoricensis root extracts." In The 1st International E-Conference on Antioxidants in Health and Disease. MDPI, 2020. http://dx.doi.org/10.3390/cahd2020-08931.

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Huang, Qing, You-Tong Wu, Hui-Ling Tan, Choon-Nam Ong, and Han-Ming Shen. "Abstract PR-3: A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress." In Abstracts: Frontiers in Cancer Prevention Research 2008. American Association for Cancer Research, 2008. http://dx.doi.org/10.1158/1940-6207.prev-08-pr-3.

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Daly, G., C. M. Francis, V. M. Pastukh, D. Absher, R. J. Langley, and M. N. Gillespie. "Rapid Redistribution of Oxidative Base Damage in DNA Regulatory Sequences Accompanies Transcriptional Modulation by Hypoxia in the Human Endothelial Cell Genome." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4191.

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Kapur, Arvinder, Mildred Felder, Lucas Fass, et al. "Abstract AP15: MODULATION OF OXIDATIVE STRESS AND SUBSEQUENT INDUCTION OF APOPTOSIS AND ENDOPLASMIC RETICULUM STRESS ALLOWS CITRAL TO DECREASE CANCER CELL PROLIFERATION." In Abstracts: 11th Biennial Ovarian Cancer Research Symposium; September 12-13, 2016; Seattle, WA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1557-3265.ovcasymp16-ap15.

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Okagu, Innocent, Joseph Ndefo, Christian Chibwuogwu, Emmanuel Aham, and Amarachukwu Onoh. "Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Rats by Deep Root Herbal Mixture®—A Nigerian Branded Polyherbal Drug." In The 1st International E-Conference on Antioxidants in Health and Disease. MDPI, 2020. http://dx.doi.org/10.3390/cahd2020-08562.

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Leick, Edna A., Luciana Aristoteles, Fabiana Reis, et al. "Modulation Of Peripheral Lung Tissue Of Mechanical And Oxidative Stress Response By Inhibiting Arginase And INOS In An Experimental Model Of Chronic Pulmonary Inflammation." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4158.

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Shiau, Jeng-Yuan, Kyoko Nakagawa-Goto, Kuo-Hsiung Lee, Wai-Leng Lee, Jacquelyn Gervay-Hague, and Lie-Fen Shyur. "Abstract A74: Modulation of oxidative stress and exosome activity by phytoagent deoxyelephantopin (DET) and its derivative treatment in suppressing triple negative breast cancer cell functions." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-a74.

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"Voltage Modulation Scanned Probe Oxidation." In Microprocesses and Nanotechnology '98. 1998 International Microprocesses and Nanotechnology Conference. IEEE, 1998. http://dx.doi.org/10.1109/imnc.1998.730080.

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Reports on the topic "Oxidative modulation"

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DeWeese, Theodore L. Biomarkers of Oxidative Injury and Their Modulation in Prostatic Tissue from Patients With Prostate Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada407245.

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Huang, Haifeng, Christopher Carlen, Brandon Rotavera, and Craig Taatjes. Time-Resolved, NIR Two-Tone Frequency Modulation Spectroscopy for Quantitative Measurement of HO2 Radical in Fuel Oxidation Reactions. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1810048.

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