Academic literature on the topic 'Oxidative synthesis'

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Journal articles on the topic "Oxidative synthesis"

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S., CHANDRASEKARAN. "Substituent Directed Oxidative Cyclisation. Application to the Synthesis of Natural Products." Journal Of India Chemical Society Vol.66, April 1989 (1989): 219–25. https://doi.org/10.5281/zenodo.5939981.

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Capperucci, Antonella, and Damiano Tanini. "Synthesis of Nitroarenes by Oxidation of Aryl Amines." Chemistry 4, no. 1 (2022): 77–97. http://dx.doi.org/10.3390/chemistry4010007.

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Nitro compounds are an important class of organic molecules with broad application in organic synthesis, medicinal chemistry, and materials science. Among the variety of methodologies available for their synthesis, the direct oxidation of primary amines represents an attractive alternative route. Efforts towards the development of oxidative procedures for the synthesis of nitro derivatives have spanned over the past decades, leading to a wide variety of protocols for the selective oxidative conversion of amines to nitro derivatives. Methods for the synthesis of nitroarenes via oxidation of ary
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Guo, Bin, Devasier Bennet, Daniel J. Belcher, Hyo-Gun Kim, and Gustavo A. Nader. "Chemotherapy agents reduce protein synthesis and ribosomal capacity in myotubes independent of oxidative stress." American Journal of Physiology-Cell Physiology 321, no. 6 (2021): C1000—C1009. http://dx.doi.org/10.1152/ajpcell.00116.2021.

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Chemotherapeutic agents (CAs) are first-line antineoplastic treatments against a wide variety of cancers. Despite their effectiveness in halting tumor progression, side effects associated with CAs promote muscle loss by incompletely understood mechanisms. To address this problem, we first identified how oxidative stress impairs protein synthesis in C2C12 myotubes. Transient elevations in reactive oxygen species (ROS) resulted in protein synthesis deficits and reduced ribosomal (r)RNA levels. Oxidative stress did not reduce rRNA gene (rDNA) transcription, but it caused an increase in rRNA and p
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Qin, Bei, Kuan Yang, and Ruijun Cao. "Synthesis and Antioxidative Activity of Piperine Derivatives Containing Phenolic Hydroxyl." Journal of Chemistry 2020 (July 21, 2020): 1–9. http://dx.doi.org/10.1155/2020/2786359.

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Piperine was used in this study in its raw form, and different steps, such as amide hydrolysis and amidation, were used to synthesize piperine derivatives containing a phenolic hydroxyl group. DPPH and ABTS free radical scavenging assays were used to assess piperine derivative antioxidant activities. We constructed an AAPH oxidative stress erythrocyte model to study the effect of piperine derivatives on the hemolysis rate of oxidatively damaged erythrocytes as well as the hemoglobin oxidation rate. This AAPH model was also used to determine piperine derivative effects on antioxidant enzyme act
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Kiss, Loránd, Melinda Nonn, Lamiaa Ouchakour, and Attila M. Remete. "Application of Oxidative Ring Opening/Ring Closing by Reductive Amination Protocol for the Stereocontrolled Synthesis of Functionalized Azaheterocycles." Synlett 33, no. 04 (2021): 307–28. http://dx.doi.org/10.1055/s-0040-1719850.

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AbstractThe current Account gives an insight into the synthesis of some N-heterocyclic β-amino acid derivatives and various functionalized saturated azaheterocycles accessed from substituted cycloalkenes via ring C=C bond oxidative cleavage followed by ring closing across double reductive amination. The ring-cleavage protocol has been accomplished according to two common approaches: a) Os-catalyzed dihydroxylation/NaIO4 vicinal diol oxidation and b) ozonolysis. A comparative study on these methodologies has been investigated. Due to the everincreasing relevance of organofluorine chemistry in d
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Lepine, Allan J., Malcolm Watford, R. Dean BOYD, Deborah A. Ross, and Dana M. Whitehead. "Relationship between hepatic fatty acid oxidation and gluconeogenesis in the fasting neonatal pig." British Journal of Nutrition 70, no. 1 (1993): 81–91. http://dx.doi.org/10.1079/bjn19930106.

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Hepatocytes were isolated from sixteen fasting neonatal pigs and used in two experiments: (1) to determine the effect of various factors on the ability for hepatic oxidation of fatty acids and (2) to clarify the relationship between fatty acid oxidation and glucose synthesis. In Expt 1, newborn pigs were either fasted from birth for 24 h or allowed to suck ad lib. for 3 d followed by a 24 h fast. In the presence of pyruvate, oxidation of octanoate (2 mM) was about 30-fold greater than oleate (1 mM) regardless of age, but glucose synthesis was not enhanced beyond that observed for pyruvate alon
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Canesi, Sylvain. "Rapid Formation of Advanced Scaffolds from Phenols and Anilines." Synlett 30, no. 06 (2018): 647–64. http://dx.doi.org/10.1055/s-0037-1610340.

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This article is an account of our efforts over the last decade to functionalize phenols and anilines at any position and to use these compounds to generate substituted aromatic systems and advanced unsaturated cyclohexanone moieties, enabling the rapid formation of complex structures. Total syntheses of numerous natural products involving such intermediates were achieved.1 Introduction2 ortho-Functionalization of Phenols and Aniline Derivatives Mediated by Iodanes (III) and Synthesis of Panacene2.1 Cross-Coupling with Aniline Derivatives2.2 Dearomative Cycloaddition of Arenes and Heteroarenes2
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Faisal, Muhammad, Mukhtiar Ahmed, Sarwat Hussain, Fayaz Ali Larik, and Aamer Saeed. "Investigating the effectiveness of classical and eco-friendly approaches for synthesis of dialdehydes from organic dihalides." Green Processing and Synthesis 8, no. 1 (2019): 635–48. http://dx.doi.org/10.1515/gps-2019-0034.

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Abstract Monoaldehydes and dialdehydes are parts of millions of compounds and are extremely versatile intermediates. For the synthesis of monoaldehydes, one impressive approach to date, because of its excellent selectivity, high yield and stability towards over-oxidation and over-reduction, is the oxidation of organic monohalides. Numerous monohalides oxidation based methodologies to afford monoaldehydes are disclosed in literature. In this research work, twelve well-known approaches (well-documented for synthesis of monoaldehydes from monohalides) are investigated for their effectiveness towa
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Savina, Luisa, and Aleksandr Sokolov. "Synthesis of condensed morpholine-containing systems by reductive or oxidative heterocyclisation." From Chemistry Towards Technology Step-By-Step 4, no. 3 (2023): 69–75. http://dx.doi.org/10.52957/2782-1900-2024-4-3-69-75.

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The article examines the reduction of N (2,4 dinitrophenyl)morpholine in acidic medium by tin (II) chloride. Under these conditions there is a formation of a mixture of products of reduction, chlorination and heterocyclisation reactions. The authors developed a method for the preparation of condensed 3,4 dihydro-1H-benzo[4,5]imidazo[2,1-c][1,4]oxazines by reduction of (2-nitro-4-R-phenyl)morpholine into 5-R-2-piperidin-1-ylanilines followed by oxidative heterocyclisation with supramuravic acid.
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Baklagin, Vladimir, Vyacheslav Baklagin, and Igor Abramov. "Synthesis of substituted 2,2'- and 4,4'-biphenyldiols using oxidative coupling reaction." From Chemistry Towards Technology Step-By-Step 4, no. 4 (2023): 131–37. http://dx.doi.org/10.52957/2782-1900-2024-4-4-131-137.

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Based on the oxidative coupling reaction, methods for the synthesis of substituted 2,2'- and 4,4'-biphenyldiols have been developed. These biphenyldiols were not described in the literature. The article presents the potential applications and limitations of the method using potassium ferricyanide and iron (III) chloride hexahydrate.
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Dissertations / Theses on the topic "Oxidative synthesis"

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Ferrara, Steven. "Oxidative radical cyclisations for total synthesis." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:f91dbfcd-4e9a-41f6-8e16-b86855930c3f.

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Manganese(III) acetate mediated radical cyclisations provide a mild and powerful tool in the construction of complex bicyclic systems. This thesis focuses on the formation of a number of alkenyl substituted [3.3.0]-bicyclic γ-lactones utilising a manganese(III) acetate/copper(II) triflate induced radical cyclisation. The methodology was then applied to a short catalytic and enantioselective synthesis of (+)-aphanamol I and related natural products. Chapter 1 presents a summary of the theories and methodology which will be utilised in this work. In particular, a key focus will revolve around ox
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Palaty, Jan. "Oxidative coupling of dibenzylbutanolides catalyzed by plant cell culture extracts." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29710.

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This thesis aims to develop a new and inexpensive synthetic route to the anti-cancer drug etoposide (6) via 4'-demethylpodophyllotoxin (4) or 4'-demethylepipodophyllotoxin (5) involving the oxidative coupling of a dibenzylbutanolide catalyzed by a cell-free extract (CFE) from plant cell culture. This step was studied in depth using the Catharanthus roseus CFE-catalyzed biotransformation of frans-2-(3,5-dimethoxy-4-hydroxybenzyl)-3-(3-hydroxy-4-methoxybenzyl)butanolide (58) to 1-(3,5-dimethoxy-4-hydroxyphenyl)-6-hydroxy-3-hydroxymethyl-7-methoxy-1,2,3,4-tetrahydro-2-naphthoic acid γ lactone (5
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Hughes, D. D. "The synthesis and oxidative cyclisation of lignans." Thesis, Swansea University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637339.

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The work described in this thesis outlines the achiral synthesis of lignans and their oxidation. Chapter one classifies lignans and examines their natural occurrence and biological activities. The biosynthesis and synthesis of lignans is also reviewed. Chapter two describes the selective synthesis of <I>trans</I>-dibenzylbutyrolactone lignans. Tandem conjugate addition to 2(5<I>H</I>)-furanone utilising diphenyl thioacteals as acyl anion equivalents, followed by <I>in situ</I> trapping with aromatic benzyl bromides, afforded the adducts in good yields. Desulfurisation yielded the <I>trans</I>-
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Martinez, Sandra Ainsua. "Oxidative radical cyclisations for the synthesis of lactones." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:4a8185e5-41fb-409c-9856-88f51b71912c.

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The object of study of this thesis lies on the optimisation of the oxidative radical cyclisation methodology for the preferential formation of gamma-lactones from unsaturated alkyl malonate derivatives. <strong>Chapter 1</strong> introduces the concept of free-radical cyclisation; more extensive explanations are given for the intramolecular oxidative radical cyclisation using manganese(III) and copper(II) salts as oxidants. An overview of the contribution of the Burton group in the field is given, in which both the applicability and the limitations of the transformation are showcased. <strong>
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Allott, Keith. "The oxidative elimination and ring expansion expansions of heterocyclic nitromethyl compounds." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329598.

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Dunlop, Robert. "Synthesis, stereochemistry and metabolism of small ring heterocycles." Thesis, Queen's University Belfast, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317057.

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ametsetor, ebenezer, Emmanuel Onobun, and Ismail Kady. "Synthesis of Hydroxytyrosol Derivatives." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/64.

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Hydroxytyrosol is one of the most powerful known antioxidants. It is a naturally occurring polyphenol, most commonly produced in Olive tree, (Olea europaea). The remarkable antioxidant and pharmacological properties of hydroxytyrosol has made it an outstanding compound in the polyphenol family and of great interest to many researchers. Hydroxytyrosol has the ability to scavenge free radicals produced during cellular oxidative stress and helps to protect the integrity of cells in living systems. Despite its numerous biological and pharmacological uses, it is found in very low concentration in o
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Head, Geoffrey Douglas. "Oxidative approaches to the synthesis of bis-tetrahydrofuran Annonaceous acetogenins." Thesis, University of Southampton, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401826.

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Mohammed, Azzam. "Diastereo- and chemoselective oxidative monocyclisations of trienes : application of permanganate mediated oxidative cyclisation to the synthesis of eurylene." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/384993/.

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A formal synthesis of eurylene (1.1) has been achieved where both trans- and cis-THF fragments were synthesised using diastereo- and chemoselective oxidative monocyclisations of triene systems. Synthesis of the trans-THF aldehyde fragment 1.50 of eurylene was accomplished starting from nerol, using (+)-trans tritylcyclohexanol (TTC) as a chiral auxiliary to direct the stereosfacial selectivity during the oxidative cyclisation of 1,5,9-triene 1.185 by sodium permanganate. The oxidative cyclisation used the new chiral auxiliary (TTC) as a highly effective chiral controller for the formation of t
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Akram, Sadia. "Synthesis of Dibenzofurans via a Palladium Catalyzed Oxidative Ring Closure Reaction." ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/honors_theses/29.

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The cannabinoid partial agonist BAY 59-3704 has been identified as an attractive target to explore structure-activity relationships at cannabinoid receptors for the development of a therapeutic agent for psychostimulant addiction. This thesis will describe the studies associated with the optimization of a palladium-catalyzed oxidative ring closure reaction for the synthesisof dibenzofuran analogues from substituted diaryl ethers. These dibenzofurans are viewed as rigid analogues of BAY 59-3704 and will provide useful information about molecular interactions at cannabinoid receptors. The scope
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Books on the topic "Oxidative synthesis"

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Holland, H. L. Organic synthesis with oxidative enzymes. VCH, 1992.

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Holland, Herbert L. Organic synthesis with oxidative enzymes. VCH, 1991.

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J, Mijs W., and Jonge, Cornelis R. H. I. de, 1940-, eds. Organic syntheses by oxidation with metal compounds. Plenum Press, 1986.

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Yang, Li. Synthesis and characterisation of oligomer distributions of alkanol ethoxylates and characterisationof structural changes during oxidative thermal degradation of poly(alkylene glycols) by high resolution 1H and 13C NMR. University of Manchester, 1994.

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Muirhead-Hofmann, K. M. Science of synthesis: Reagents : oxidation. Georg Thieme, 2010.

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E, Wolf Eduardo, ed. Methane conversion by oxidative processes: Fundamental and engineering aspects. Van Nostrand Reinhold, 1992.

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M, De Pontes, ed. Natural gas conversion IV: Proceedings of the 4th International Natural Gas Conversion Symposium, Kruger Park, South Africa, November 19-23, 1995. Elsevier, 1997.

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Mahrwald, Rainer. Enantioselective Organocatalyzed Reactions I: Enantioselective Oxidation, Reduction, Functionalization and Desymmetrization. Springer Science+Business Media B.V., 2011.

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Mijs, W. J., and C. R. H. I. de Jonge, eds. Organic Syntheses by Oxidation with Metal Compounds. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2109-5.

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M, Roberts Stanley, and Poignant Geraldine, eds. Hydrolysis, oxidation and reduction. Wiley, 2002.

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Book chapters on the topic "Oxidative synthesis"

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Mashiko, Tomoya, Yuta Shingai, Jun Sakai, et al. "Enantioselective Total Syntheses of (−)-Cochlearol B and (+)-Ganocin A." In Modern Natural Product Synthesis. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1619-7_16.

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AbstractHerein, we describe the first total synthesis of (±)-cochlearol B and the enantioselective total syntheses of (−)-cochlearol and (+)-ganocin A. The key steps include Corey-Bakshi-Shibata reduction, oxidative phenolic cyclization, intramolecular [2+2] photocycloaddition, and intramolecular radical cyclization-benzylic oxidative cyclization, enabling efficient access to 4/5/6/6/6 and 5/5/6/6/6-fused pentacyclic frameworks of these natural products.
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Williamson, Alice E., and Matthew J. Gaunt. "Oxidative Dearomatization and Organocatalytic Desymmetrization." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch48.

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Moeller, Kevin D., and Luzviminda V. Tinao. "Oxidative Organic Electrochemistry: Intramolecular Enol Ether Coupling Reactions." In Electroorganic Synthesis. Routledge, 2023. http://dx.doi.org/10.1201/9780203758571-22.

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Magyar, K., M. Pálfi, V. Jenei, and É. Szökő. "Deprenyl: from chemical synthesis to neuroprotection." In Oxidative Stress and Neuroprotection. Springer Vienna, 2006. http://dx.doi.org/10.1007/978-3-211-33328-0_16.

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Ingwall, Joanne S. "ATP Synthesis Pathways: Oxidative Phosphorylation." In Basic Science for the Cardiologist. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-1093-2_10.

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Basso, Andrea, Lisa Moni, and Renata Riva. "Multicomponent Reactions under Oxidative Conditions." In Multicomponent Reactions in Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2014. http://dx.doi.org/10.1002/9783527678174.ch10.

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Odagi, Minami, and Kazuo Nagasawa. "Oxidative Phenolic Coupling Reaction/Aza-Michael Reaction Strategy for the Synthesis of Complex Polycyclic Alkaloids." In Modern Natural Product Synthesis. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-1619-7_10.

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AbstractThe synthesis of alkaloids featuring fused polycyclic frameworks has long attracted the interest of synthetic organic communities, owing to their great structural complexity and wide variety of biological activities. Indeed, a variety of strategies for synthesizing these alkaloids have been investigated over the years. Here, we present our innovative strategy for tahe construction of complex fused polycyclic frameworks via oxidative phenolic coupling reaction and subsequent regioselective intramolecular aza-Michael reaction. We illustrate its practical application in synthetic studies
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Jackson, Stephen K., Kun-Liang Wu, and Thomas R. R. Pettus. "Sequential Reactions Initiated by Oxidative Dearomatization. Biomimicry or Artifact?" In Biomimetic Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634606.ch20.

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Utley, James H. P., and Gregor G. Rozenberg. "Useful Electro-Oxidative Conversions of Aromatic Compounds." In Novel Trends in Electroorganic Synthesis. Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_13.

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Xing, Qi, and Fuwei Li. "Synthesis of Functionalized Heterocycles via Oxidative Carbonylation." In Topics in Heterocyclic Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_156.

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Conference papers on the topic "Oxidative synthesis"

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Nunes, Felipe G., Elber V. Bendinelli, Mark D. Soucek, and Idalina V. Aoki. "Synthesis of High Solids Alkyds Modified with Reactive Diluents for Encapsulation and Use in Self-healing Coatings." In LatinCORR 2023. AMPP, 2023. https://doi.org/10.5006/lac23-20430.

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A great effort has been devoted to the research of self-healing coatings, as they provide anticorrosive protection even when the painting is damaged [1]. The encapsulation of drying oils is an established strategy to promote self-healing. Microcapsules release the seed oil upon mechanical damage, which triggers self-healing in the coating defect as the oil undergoes oxidative polymerization [2]. Alkyds are also a great candidate for microencapsulation due to their green nature, oxidative-driven polymerization, and better anticorrosive properties than seed oils [3]. However, the high viscosity
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Shirley, Harry J., and Christopher D. Bray. "A New Method of Spiroketalization via Cascade Oxidative Dearomatization." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_20138255339.

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Lisboa, Cinthia da Silva, Gustavo dos Santos, Nanci C. de Lucas, and Simon J. Garden. "Benzocarbazolquinones and Benzonaphthofurandiones by Palladium Catalyzed Oxidative C-H Functionalization." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013819114414.

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Cavinatto, Susiane, Jussara Navarini, Carson W. Wiethan, et al. "Selective oxidative aromatization of polyfunctionalized trifluoromethyl substituted chromenones by microwave irradiation." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201361017598.

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Navarini, Jussara, Helio G. Bonacorso, Carson W. Wiethan, Rosália Andrighetto, Marcos A. P. Martins, and Nilo Zanatta. "Molecular Iodine - An Efficient Oxidative Reagent for Aromatization of Trifluoromethyl Substituted Chromenones." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0009-2.

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Ishikawa, Eloisa E., André Fogaça, Andréa T. Faccio, et al. "Fluoroalcohols: Efficient Solvents for the Iodine(III)-Promoted Oxidative Rearrangement of 1,2-Dihydronaphthalenes." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0212-1.

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Kamalulazmy, Nurulain, and Nurul Izzaty Hassan. "Synthesis of novel symmetrical macrocycle via oxidative homocoupling of bisalkyne." In THE 2014 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4895213.

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Ziadan, Kareema M., Ghufran M. Shabeeb, and Safa Nasar. "Synthesis of polyaniline nano fibers by facile rapid oxidative method." In PROCEEDINGS OF THE III INTERNATIONAL CONFERENCE ON ADVANCED TECHNOLOGIES IN MATERIALS SCIENCE, MECHANICAL AND AUTOMATION ENGINEERING: MIP: Engineering-III – 2021. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0066793.

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Shaari, Helyati Abu Hassan, Mohd Nazim Mohtar, Norizah Abdul Rahman, and Muhammad Mahyiddin Ramli. "Synthesis and functional characterization of conducting polyaniline by oxidative polymerization method." In Special Issue of the 4th International Symposium on Advanced Materials and Nanotechnology (iSAMN 2020). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0084374.

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Rzaev, Ramil, Ion Geru, Natalia Sucman, and Fliur Macaev. "Synthesis - (1,4-diaminonaphthalene) by oxidative polymerization and study of its properties." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.94.

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The aim of this study was to synthesize free of metals polymeric organic materials that possess electrical conductivity. The nanoscale poly-(1,4-diaminonaphthalene) was synthesized using the oxidative polymerization method. The reaction was carried out in a hydrochloric acid solution at 0C, with potassium persulfate used as the oxidizing agent. The polymers were characterized using various techniques, including FT-IR, UV-Vis, TGA, NMR, EPR and SEM. It was found that the polymerization of 1,4-diaminonaphthalene occurs through the formation of N-C and N=C. UV studies revealed differences in the
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Reports on the topic "Oxidative synthesis"

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Bazan, Guillermo C. Ring Walking/Oxidative Addition Reactions for the Controlled Synthesis of Conjugated Polymers. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1037865.

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Amir, Rachel, David J. Oliver, Gad Galili, and Jacline V. Shanks. The Role of Cysteine Partitioning into Glutathione and Methionine Synthesis During Normal and Stress Conditions. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699850.bard.

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The objective of this research is to study the nature of the competition for cysteine (Cys), the first organic sulfur-containing compound, between its two main metabolites, glutathione (GSH) and methionine (Met). GSH plays a central role in protecting plants during various stresses, while Met, an essential amino acid, regulates essential processes and metabolites in plant cells through its metabolite S-adenosyl-Met. Our results, which are based on flux analysis and measurements of Met- metabolites, show that the flux towards Met synthesis is high during non-stress conditions, however the flux
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Horwitz, Benjamin A., and Barbara Gillian Turgeon. Fungal Iron Acquisition, Oxidative Stress and Virulence in the Cochliobolus-maize Interaction. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7709885.bard.

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Our project focused on genes for high affinity iron acquisition in Cochliobolus heterostrophus, a necrotrophic pathogen of maize, and their intertwined relationship to oxidative stress status and virulence of the fungus on the host. An intriguing question was why mutants lacking the nonribosomal peptide synthetase (NRPS) gene (NPS6) responsible for synthesis of the extracellular siderophore, coprogen, are sensitive to oxidative stress. Our overall objective was to understand the mechanistic connection between iron stress and oxidative stress as related to virulence of a plant pathogen to its h
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Pavlova, Svetlana, Aleksandr Gorkusha, Sergey Tsybulya, Anna Nartova, Vladimir Rogov, and Lubov Isupova. Ln/Fe-doped Sr2TiO4 layered perovskites: Effect of synthesis method and composition on physical-chemical and catalytic properties in oxidative coupling of methane. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2306p9583566.

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Elmann, Anat, Orly Lazarov, Joel Kashman, and Rivka Ofir. therapeutic potential of a desert plant and its active compounds for Alzheimer's Disease. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7597913.bard.

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We chose to focus our investigations on the effect of the active forms, TTF and AcA, rather than the whole (crude) extract. 1. To establish cultivation program designed to develop lead cultivar/s (which will be selected from the different Af accessions) with the highest yield of the active compounds TTF and/or achillolide A (AcA). These cultivar/s will be the source for the purification of large amounts of the active compounds when needed in the future for functional foods/drug development. This task was completed. 2. To determine the effect of the Af extract, TTF and AcA on neuronal vulnerabi
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Sionov, Edward, Nancy Keller, and Shiri Barad-Kotler. Mechanisms governing the global regulation of mycotoxin production and pathogenicity by Penicillium expansum in postharvest fruits. United States Department of Agriculture, 2017. http://dx.doi.org/10.32747/2017.7604292.bard.

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The original objectives of the study, as defined in the approved proposal, are: To characterize the relationship of CreA and LaeA in regulation of P T production To understand how PacC modulates P. expansumpathogenicity on apples To examine if other secondary metabolites are involved in virulence or P. expansumfitness To identify the signaling pathways leading to PAT synthesis Penicilliumexpansum, the causal agent of blue mould rot, is a critical health concern because of the production of the mycotoxinpatulin (PAT) in colonized apple fruit tissue. Although PAT is produced by many Penicilliums
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Delmer, Deborah P., Douglas Johnson, and Alex Levine. The Role of Small Signal Transducing Gtpases in the Regulation of Cell Wall Deposition Patterns in Plants. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570571.bard.

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The combined research of the groups of Delmer, Levine and Johnson has led to a number of interesting findings with respect to the function of the small GTPase Rac in plants and also opened up new leads for future research. The results have shown: 1) The Rac13 protein undergoes geranylgeranlyation and is also translocated to the plasma membrane as found for Rac in mammals; 2) When cotton Rac13 is highly- expressed in yeast, it leads to an aberrant phenotype reminiscent of mutants impaired in actin function, supporting a role for Rac13 in cytoskeletal organization; 3) From our searches, there is
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Prusky, Dov, Noel Keen, and John Browse. Modulation of the synthesis of the main preformed antifungal compound as abasis for the prevention of postharvest disease of C. gloeosporioides in avocado fruits. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7575273.bard.

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The most important pathological factor limiting fruit life after harvest in subtropical fruits are quiescent infections of anthracnose caused by Colletotrichum gloeosporioides. Prusky and Keen elucidated the mechanism of resistance in avocado fruits to quiescent infections of C. gloeosporioides and determined that the major biocide involved is the preformed compound,1-acetoxy-2-hydroxy-4-oxo-heneicosa-13, 15 diene. Two possibilities exist for maintaining fungitoxic levels of antifungal compounds in the tissue of ripening fruits: (i). Prevention of catabolism (ii). Induction of synthesis. Previ
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Chacon, L. C. The synthesis, characterization and reactivity of high oxidation state nickel fluorides. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/335167.

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Edward H. Robey, Jr, and Randall S. Gemmen. A Partial Oxidation Technique for Fuel-Cell Anode Exhaust-Gas Synthesis. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/1658.

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